CN105213889A - One treats prostatitic Chinese medicine oral liquid and preparation method - Google Patents
One treats prostatitic Chinese medicine oral liquid and preparation method Download PDFInfo
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Abstract
The open one of the present invention treats prostatitic Chinese medicine oral liquid and preparation method, is made up: Caulis Sargentodoxae 28-32 part, Cortex Phellodendri 18-22 part, Herba Lysimachiae 28-32 part, Herba Patriniae 28-32 part, Rhizoma Atractylodis 13-17 part, Flos Lonicerae 28-32 part, Rhizoma Dioscoreae Septemlobae 18-22 part, Semen Coicis 38-42 part, Rhizoma Dioscoreae 28-32 part, Semen Vaccariae 18-22 part, Semen Euryales 18-22 part, Poria 28-32 part, Herba Plantaginis core 18-22 part, Endoconcha Sepiae 18-22 part, Radix Glycyrrhizae 5-9 part of following raw material.The present invention has effect of clearing away heat-damp and promoting diuresis, promoting flow of QI and blood, stasis-dispelling and pain-killing, and be a kind of safe and reliable, without any side effects, effective ingredient utilization rate is high, the Chinese medicine composition of instant effect.
Description
Technical field
The present invention relates to one and treat prostatitic Chinese medicine oral liquid, belong to the field of Chinese medicines.
Background technology
Prostatitis is the commonly encountered diseases of Urology Surgery, first place is accounted in Urology Surgery male patient the right side of fifty, nineteen ninety-five NIH has formulated a kind of new prostatitis sorting technique, I type: be equivalent to the acute bacterial prostatitis in conventional sorting methods, II type: be equivalent to the chronic bacterial prostatitis in conventional sorting methods, III type: prostatitis chronic Pelvic Pain Syndrome, IV type: silent prostatitis, wherein nonbacterial prostatitis is common far beyond bacterial prostatitis, the cause of disease only has small number of patients to have acute medical history, show as chronic more, recurrent passes through, I type and II type prostatitis main pathogenic are pathogenic infection, pathogen invades prostate with urine, cause infecting, pathological anatomy confirms that prostatitis pathological changes is generally confined to peripheral zone, with urine, glandular tube flows that vertical line is reverse is opened on Posterior urethral herein, easily cause urine reflux, and central zone and transitional zone glandular tube move towards consistent with urine flow path direction, not easily infect, III type pathogenesis is not bright, etiology is very complicated, there is extensively dispute, most scholar thinks that its Etiological may be pathogenic infection, urinary dysfunction, psychologic factors, neuroendocrine factor, immunoreaction abnormity, oxidative stress theory, lower urinary tract epithelium dysfunction etc., IV type lacks relevant pathogenetic research, may be identical with the part cause and onset of disease mechanism of III type, nearest research also finds that the urate of urine not only has stimulation to prostate, also precipitable one-tenth calculus, blocking glandular tube, as the protection place of antibacterial, these discoveries can illustrate the coexpress that prostatitis syndrome is various diseases in fact, and complicated clinical manifestation is changeable, various complication can be produced, the western medical treatment Main Means taked this disease at present uses antiinflammatory, analgesic drug product, but western medicine is temporary transient symptom management mostly, life-time service easily produces dependency and toxic and side effects, Chinese medicine can improve prostate and even urinary system local immunity power, and the state of an illness not easily recurs.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide one and treat prostatitic Chinese medicine oral liquid, it has effect of clearing away heat-damp and promoting diuresis, promoting flow of QI and blood, stasis-dispelling and pain-killing.
The present invention is achieved through the following technical solutions:
One treats prostatitic Chinese medicine oral liquid, is made up of following raw material: Caulis Sargentodoxae 28-32 part, Cortex Phellodendri 18-22 part, Herba Lysimachiae 28-32 part, Herba Patriniae 28-32 part, Rhizoma Atractylodis 13-17 part, Flos Lonicerae 28-32 part, Rhizoma Dioscoreae Septemlobae 18-22 part, Semen Coicis 38-42 part, Rhizoma Dioscoreae 28-32 part, Semen Vaccariae 18-22 part, Semen Euryales 18-22 part, Poria 28-32 part, Herba Plantaginis core 18-22 part, Endoconcha Sepiae 18-22 part, Radix Glycyrrhizae 5-9 part.
Preferably, each parts by weight of raw materials is: Caulis Sargentodoxae 30 parts, Cortex Phellodendri 20 parts, Herba Lysimachiae 30 parts, Herba Patriniae 30 parts, Rhizoma Atractylodis 15 parts, Flos Lonicerae 30 parts of, Rhizoma Dioscoreae Septemlobae 20 parts, Semen Coicis 40 parts, Rhizoma Dioscoreae 30 parts, Semen Vaccariae 20 parts, Semen Euryales 20 parts, 30 parts, Poria, Herba Plantaginis core 20 parts, Endoconcha Sepiae 20 parts, 7 parts, Radix Glycyrrhizae.
Pharmacological action:
Caulis Sargentodoxae: nature and flavor with return through: bitter, flat; Return large intestine, Liver Channel, function with cure mainly: heat-clearing and toxic substances removing, invigorate blood circulation, dispel the wind; For abdominalgia with intestinal abscess, amenorrhea dysmenorrhea, rheumatic arthralgia, tumbling and swelling.
Cortex Phellodendri: nature and flavor with return through: bitter, cold; Return kidney, urinary bladder channel, function with cure mainly: heat clearing and damp drying, pathogenic fire purging except steam, detoxification sore treatment; For damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, beriberi, flaccidity is warded off, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema pruritus; Stir-baked CORTEX PHELLODENDRI with salt solution nourishing YIN to lower pathogenic fire; For hyperactivity of fire caused by deficiency of YIN, night sweat hectic fever due to YIN-deficiency.
Herba Lysimachiae: nature and flavor with return through: sweet, salty, be slightly cold; Return liver, gallbladder, kidney, urinary bladder channel, function with cure mainly: eliminating damp-heat, treating stranguria, detumescence; For pyretic stranguria, Sha Lin, urinates and puckeryly to have a pain, jaundice dark coloured urine, carbuncle furuncle, venom; Liver and bile stone, lithangiuria.
Herba Patriniae: meridian distribution of property and flavor: pungent, bitter, is slightly cold; Return stomach, large intestine, Liver Channel; Effect: heat-clearing and toxic substances removing, eliminating carbuncle evacuation of pus, stasis-dispelling and pain-killing; Function cures mainly: heat-clearing and toxic substances removing, removing blood stasis and expelling pus; For appendicitis, dysentery, enteritis, hepatitis, eye conjunctivitis, postnatal blood stasis stomachache, carbuncle furuncle.
Rhizoma Atractylodis: nature and flavor with return through: pungent, bitter, temperature; Return spleen, stomach, Liver Channel, function with cure mainly: drying damp and strengthening spleen, expelling wind and cold, improving eyesight; For distension and fullness in the abdomen, have loose bowels, edema, beriberi flaccidity of feet with lamenness, rheumatic arthralgia, anemofrigid cold, nyctalopia.
Flos Lonicerae: nature and flavor with return through: sweet, cold; Return lung, the heart, stomach warp, function with cure mainly: heat-clearing and toxic substances removing, wind-heat dissipating; For carbuncle furuncle, sore throat, erysipelas, toxic-heat and blood stasis, anemopyretic cold, epidemic febrile disease is generated heat.
Rhizoma Dioscoreae Septemlobae: nature and flavor are bitter is flat; Gui Jing returns kidney, stomach warp; Effect: dampness removing goes turbid, wind expelling stagnation removing; Cure mainly for stranguria marked by chyluria, nebulousurine, leukorrhagia, rheumatic arthralgia, articular instability, lumbocrural pain.
Semen Coicis: nature and flavor with return through: sweet, light, cool; Return spleen, stomach, lung meridian, function with cure mainly: spleen invigorating eliminating dampness by diuresis, eliminating impediment antidiarrheal, heat clearing away row dense; For edema, beriberi, dysuria, arthralgia chiefly caused by damp pathogen contracture, diarrhea due to hypofunction of the spleen, lung abscess, intestinal carbuncle; Verruca plana.
Rhizoma Dioscoreae: nature and flavor with return through: sweet, flat; Return spleen, lung, kidney channel, function with cure mainly: spleen reinforcing nourishing the stomach, promote the production of body fluid lung benefiting, the kidney invigorating arresting seminal emission; For insufficiency of the spleen lack of appetite, incessant chronic diarrhea, the deficiency of the lung is breathed with cough, emission due to deficiency of the kidney, leukorrhagia, frequent micturition, and deficiency-heat is quenched one's thirst; Rhizoma Dioscoreae (parched with bran) spleen reinforcing stomach invigorating; For insufficiency of the spleen lack of appetite, loose stool of having loose bowels, leukorrhagia.
Semen Vaccariae: nature and flavor with return through: bitter, flat; Return liver, stomach warp, function with cure mainly: promoting blood circulation to restore menstrual flow, stimulating milk secretion subside a swelling; For agalactia, amenorrhea, dysmenorrhea, acute mastitis swells and ache.
Semen Euryales: nature and flavor with return through: sweet, puckery, flat; Return spleen, kidney channel, function with cure mainly: supplementing the kidney to control the nocturnal, spleen reinforcing antidiarrheal, damp eliminating leukorrhagia stopping; For emission, enuresis frequent micturition, insufficiency of the spleen chronic diarrhea, nebulousurine, leukorrhagia.
Poria: nature and flavor with return through: sweet, light, flat; GUIXIN, lung, spleen, kidney channel, function with cure mainly: promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming; For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia;
Herba Plantaginis core: nature and flavor with return through: sweet, be slightly cold; Return liver, kidney, lung, small intestine meridian, function with cure mainly: clearing away heat and promoting diuresis, eliminating dampness by diuresis is treating stranguria, improving eyesight, eliminates the phlegm; For edema distension, the puckery pain of pyretic stranguria, diarrhea due to summer heat and dampness, conjunctival congestion and swelling pain, phlegm-heat cough.
Endoconcha Sepiae: meridian distribution of property and flavor: salty, puckery, temperature; Return spleen, kidney channel, function cures mainly: astringing to arrest bleeding, relieving leukorrhea by astringents, antacid, sore; For acid regurgitation of having a stomachache, hematemesis and epistaxis, metrorrhagia is had blood in stool, emission and spermatorrhea, leucorrhea with red and white discharge; Peptic Ulcers; External treatment bleeding due to trauma, the many pus of skin ulcer.
Radix Glycyrrhizae: nature and flavor with return through: sweet, flat; GUIXIN, lung, spleen, stomach warp, function with cure mainly: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription; For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Another technical problem to be solved by this invention is to provide a kind of preparation method preparing above-mentioned Chinese medicine oral liquid.
Another technical problem to be solved by this invention is achieved through the following technical solutions:
Treat a preparation method for prostatitic Chinese medicine oral liquid, be prepared from by following methods:
(1) get raw material Caulis Sargentodoxae, Cortex Phellodendri, Herba Lysimachiae, Herba Patriniae, Rhizoma Atractylodis, Herba Plantaginis core, Endoconcha Sepiae, Radix Glycyrrhizae put into boiling machine, with cold water soak 30-50 minute, then above-mentioned raw materials volume 5-10 soak by water secondary is doubly added, each 2-4 hour, collecting decoction, filters, and collects filtrate, obtain filtrate, for subsequent use;
(2) get raw material Flos Lonicerae, Rhizoma Dioscoreae Septemlobae, Semen Coicis, Rhizoma Dioscoreae, Semen Vaccariae, Semen Euryales, Poria put into boiling machine, with cold water soak 30-50 minute, then add above-mentioned raw materials volume 5-10 soak by water secondary doubly, each 2-4 hour, collecting decoction, filters, collect filtrate, obtain filtrate, for subsequent use;
(3) gained filtrate in gained filtrate in step (1) and step (2) is put into container to be fully uniformly mixed, agitator revolution is 300-500r/min, then the ethanol of 50-80% is added by volume, leave standstill 24-48 hour, filter, filtrate recycling ethanol, refilters, obtain admixing medical solutions, for subsequent use;
(4) gained admixing medical solutions in step (3) is put into ultrafilter to filter, the average pore size scope of the filter membrane of described ultrafilter is 20-50nm, and the pressure limit crossed in filter fly is 0.1-0.4MPa, and the scope of the crossflow velocity in filter process is 3-6m/s, obtain filtrate, for subsequent use;
(5) gained filtrate in step (4) is sent into receiver, in receiver, be evaporated to the clear paste of relative density 1.01-1.08 during 60-65 DEG C, obtain clear paste, for subsequent use;
(6) by gained clear paste in step (5) by sodium hydroxide solution adjust ph to 6.0-8.0, embedding is in soda-lime glass tubular oral liquid bottle again, and fill is rolled lid and is placed on 95-98 DEG C of condition, sterilizing 15-18min, warehouse-in is finished product, must treat prostatitic Chinese medicine oral liquid.
Preferably, a kind of preparation method for the treatment of prostatitic Chinese medicine oral liquid, is prepared from by following methods:
(1) get raw material Caulis Sargentodoxae, Cortex Phellodendri, Herba Lysimachiae, Herba Patriniae, Rhizoma Atractylodis, Herba Plantaginis core, Endoconcha Sepiae, Radix Glycyrrhizae put into boiling machine, by cold water soak 30 minutes, then add the soak by water secondary of above-mentioned raw materials volume 10 times, each 2 hours, collecting decoction, filtered, collect filtrate, obtain filtrate, for subsequent use;
(2) get raw material Flos Lonicerae, Rhizoma Dioscoreae Septemlobae, Semen Coicis, Rhizoma Dioscoreae, Semen Vaccariae, Semen Euryales, Poria put into boiling machine, by cold water soak 30 minutes, then add the soak by water secondary of above-mentioned raw materials volume 10 times, each 2 hours, collecting decoction, filtered, collect filtrate, obtain filtrate, for subsequent use;
(3) gained filtrate in gained filtrate in step (1) and step (2) is put into container to be fully uniformly mixed, agitator revolution is 400r/min, then adds the ethanol of 70% by volume, leave standstill 48 hours, filter, filtrate recycling ethanol, refilter, obtain admixing medical solutions, for subsequent use;
(4) gained admixing medical solutions in step (3) is put into ultrafilter to filter, the average pore size of the filter membrane of described ultrafilter is 50nm, and the pressure limit crossed in filter fly is 0.4MPa, and the scope of the crossflow velocity in filter process is 5m/s, obtains filtrate, for subsequent use;
(5) gained filtrate in step (4) is sent into receiver, when being evaporated to 65 DEG C in receiver, the clear paste of relative density 1.08, obtains clear paste, for subsequent use;
(6) by gained clear paste sodium hydroxide solution adjust ph to 6.8 in step (5), embedding is in soda-lime glass tubular oral liquid bottle again, and fill is rolled lid and is placed on 98 DEG C of conditions, sterilizing 15min, warehouse-in is finished product, must treat prostatitic Chinese medicine oral liquid.
Beneficial effect: the present invention has effect of clearing away heat-damp and promoting diuresis, promoting flow of QI and blood, stasis-dispelling and pain-killing, be a kind of safe and reliable, without any side effects, effective ingredient utilization rate is high, the Chinese medicine composition of instant effect.
The present invention adopts pure Chinese medicine to be raw material, according to prostatitic pathogenic factor and Clinical symptoms, under instruction of Chinese Medicine theory, carry out prescription be prepared from the basis not being raw-material activity, show through clinical efficacy, this medicine has definite curative effect to prostatitis, is a kind of ideal treatment medication of prostatitis patient.
Model case
Case 1: Mr. Jia, 42 years old, medical history: main suit's frequent micturition, urine retention, urine drip white, without obvious inducement, patient occurred that frequent micturition, urine retention, urine dripped before half a year white, hospital diagnosis is: prostatitis, after taking a course for the treatment of of Drug therapy of the present invention, after treatment, patient's subjective symptoms obviously reduces, then after taking a course for the treatment of of medicine of the present invention, patient's above-mentioned symptom disappears completely.
Case 2: Mr. Cui, 39 years old, medical history: main suit urinates discomfort, burning sensation, urethral orifice adularescent secretions, patient found dampness of scrotum before three months, there is abnormal flavour, occur discomfort of urinating, have burn feeling, companion's urethral orifice adularescent secretions, perineal position falling inflation pain, diagnosis: prostatitis, after taking a course for the treatment of of Drug therapy of the present invention, after treatment, patient's subjective symptoms obviously reduces, then after taking a course for the treatment of of medicine of the present invention, patient's above-mentioned symptom disappears completely.
Case 3: Mr. Fang, 35 years old, medical history: suffer from prostatitis 2 years, separating urine has seminal fluid to flow out often, has most pus cell, with lumbago and backache in urine, the symptoms such as fear of cold, after taking a course for the treatment of of Drug therapy of the present invention, after treatment, patient's subjective symptoms obviously reduces, and after taking two courses for the treatment of of medicine of the present invention, patient's above-mentioned symptom disappears completely.
Case 4: Mr. Gu, man, 27 years old, medical history: occur frequent micturition, stranguria, urine retention sense over one year, perineum and lower abdomen pain are uncomfortable, eventually the white secretions of end urine band, and nearly January goes up disease increasing the weight of afterwards because of fatigue, patient mental is nervous, very painful, diagnosis: prostatitis, after taking a course for the treatment of of Drug therapy of the present invention, after treatment, patient's subjective symptoms obviously reduces, then after taking two courses for the treatment of of medicine of the present invention, patient's above-mentioned symptom disappears completely.
Case 5: Mr. Xiang, 44 years old, there is frequent micturition, dysurea before 3 years, dripping urine, perineum distending pain, distention and pain in the lower abdomen, waist sacrum is aching and tired, insomnia and dreamful sleep, once be prostatitis at hospital diagnosis, after taking a course for the treatment of of Drug therapy of the present invention, after treatment, patient's subjective symptoms obviously reduces, then after taking two courses for the treatment of of medicine of the present invention, patient's above-mentioned symptom disappears completely.
Case 6: Mr. Hou, 25 years old, medical history: frequent micturition, urgent micturition, urinate symptom half a year, perineal position are not to the utmost uncomfortable, recent nocturia increases, nocturia 3-4 time, examination in hospital is diagnosed as prostatitis, after taking a course for the treatment of of Drug therapy of the present invention, after treatment, patient's subjective symptoms obviously reduces, and after taking two courses for the treatment of of medicine of the present invention, patient's above-mentioned symptom disappears completely.
Clinical data
Physical data: prostatitis patient 50 example, the oldest person 59 years old, age reckling 22 years old, 40.5 years old mean age, course of disease 3-36 month, average 19.5 months.
Diagnostic criteria: (1) symptom one frequent micturition, urine heat, urine end not to the utmost, drip white; (2) symptom two waist sacrum, perineum, lower abdomen, groin, testis are not given up or distending pain; (3) symptom three sexual dysfunction: hyposexuality, sexual impotence, premature ejaculation, seminal emission or sterile, prostate touch: the large I of body of gland is normally many or slightly large, and two lateral lobes are asymmetric, surface imperfection, and quality is partially hard or uneven, has tenderness.
Therapeutic Method: take oral liquid of the present invention, every day 2 times, each 30ml 15 days is a course for the treatment of.
Curative effect determinate standard: recovery from illness: damp and hot stasis of blood disease and the sign of holding under the arm disappears, examination of prostatic fluid: leukocyte 2 times or more is normal, effective: damp and hot stasis of blood disease of holding under the arm disappears or alleviates, examination of prostatic fluid: leukopenia 1/2, effective: damp and hot stasis of blood disease of holding under the arm alleviates, examination of prostatic fluid: leukocyte is comparatively front to be improved; Invalid: damp and hot stasis of blood disease of holding under the arm is without improvement, and examination of prostatic fluid leukocyte is comparatively treated front without improving.
Therapeutic outcome: by this side treatment prostatitis patient 50 example, wherein clinical recovery 45 example, effective 3 examples, effective 2 examples, invalid 0 example, effective percentage is 100%.
Detailed description of the invention
Embodiment 1
The present invention treats the preparation of prostatitis Chinese medicine oral liquid, and the weight portion of each raw material is: Caulis Sargentodoxae 32 parts, Cortex Phellodendri 22 parts, Herba Lysimachiae 32 parts, Herba Patriniae 32 parts, Rhizoma Atractylodis 17 parts, Flos Lonicerae 32 parts of, Rhizoma Dioscoreae Septemlobae 22 parts, Semen Coicis 42 parts, Rhizoma Dioscoreae 32 parts, Semen Vaccariae 22 parts, Semen Euryales 22 parts, 32 parts, Poria, Herba Plantaginis core 22 parts, Endoconcha Sepiae 22 parts, 9 parts, Radix Glycyrrhizae;
Be prepared from by following methods:
(1) get raw material Caulis Sargentodoxae, Cortex Phellodendri, Herba Lysimachiae, Herba Patriniae, Rhizoma Atractylodis, Herba Plantaginis core, Endoconcha Sepiae, Radix Glycyrrhizae put into boiling machine, with cold water soak 30-50 minute, then above-mentioned raw materials volume 5-10 soak by water secondary is doubly added, each 2-4 hour, collecting decoction, filters, and collects filtrate, obtain filtrate, for subsequent use;
(2) get raw material Flos Lonicerae, Rhizoma Dioscoreae Septemlobae, Semen Coicis, Rhizoma Dioscoreae, Semen Vaccariae, Semen Euryales, Poria put into boiling machine, with cold water soak 30-50 minute, then add above-mentioned raw materials volume 5-10 soak by water secondary doubly, each 2-4 hour, collecting decoction, filters, collect filtrate, obtain filtrate, for subsequent use;
(3) gained filtrate in gained filtrate in step (1) and step (2) is put into container to be fully uniformly mixed, agitator revolution is 300-500r/min, then the ethanol of 50-80% is added by volume, leave standstill 24-48 hour, filter, filtrate recycling ethanol, refilters, obtain admixing medical solutions, for subsequent use;
(4) gained admixing medical solutions in step (3) is put into ultrafilter to filter, the average pore size scope of the filter membrane of described ultrafilter is 20-50nm, and the pressure limit crossed in filter fly is 0.1-0.4MPa, and the scope of the crossflow velocity in filter process is 3-6m/s, obtain filtrate, for subsequent use;
(5) gained filtrate in step (4) is sent into receiver, in receiver, be evaporated to the clear paste of relative density 1.01-1.08 during 60-65 DEG C, obtain clear paste, for subsequent use;
(6) by gained clear paste in step (5) by sodium hydroxide solution adjust ph to 6.0-8.0, embedding is in soda-lime glass tubular oral liquid bottle again, and fill is rolled lid and is placed on 95-98 DEG C of condition, sterilizing 15-18min, warehouse-in is finished product, must treat prostatitic Chinese medicine oral liquid.
Usage: oral, every day 2 times, each 30ml.
Embodiment 2
The present invention treats the preparation of prostatitis Chinese medicine oral liquid, and the weight portion of each raw material is: Caulis Sargentodoxae 30 parts, Cortex Phellodendri 20 parts, Herba Lysimachiae 30 parts, Herba Patriniae 30 parts, Rhizoma Atractylodis 15 parts, Flos Lonicerae 30 parts of, Rhizoma Dioscoreae Septemlobae 20 parts, Semen Coicis 40 parts, Rhizoma Dioscoreae 30 parts, Semen Vaccariae 20 parts, Semen Euryales 20 parts, 30 parts, Poria, Herba Plantaginis core 20 parts, Endoconcha Sepiae 20 parts, 7 parts, Radix Glycyrrhizae;
Be prepared from by following methods:
(1) get raw material Caulis Sargentodoxae, Cortex Phellodendri, Herba Lysimachiae, Herba Patriniae, Rhizoma Atractylodis, Herba Plantaginis core, Endoconcha Sepiae, Radix Glycyrrhizae put into boiling machine, with cold water soak 30-50 minute, then above-mentioned raw materials volume 5-10 soak by water secondary is doubly added, each 2-4 hour, collecting decoction, filters, and collects filtrate, obtain filtrate, for subsequent use;
(2) get raw material Flos Lonicerae, Rhizoma Dioscoreae Septemlobae, Semen Coicis, Rhizoma Dioscoreae, Semen Vaccariae, Semen Euryales, Poria put into boiling machine, with cold water soak 30-50 minute, then add above-mentioned raw materials volume 5-10 soak by water secondary doubly, each 2-4 hour, collecting decoction, filters, collect filtrate, obtain filtrate, for subsequent use;
(3) gained filtrate in gained filtrate in step (1) and step (2) is put into container to be fully uniformly mixed, agitator revolution is 300-500r/min, then the ethanol of 50-80% is added by volume, leave standstill 24-48 hour, filter, filtrate recycling ethanol, refilters, obtain admixing medical solutions, for subsequent use;
(4) gained admixing medical solutions in step (3) is put into ultrafilter to filter, the average pore size scope of the filter membrane of described ultrafilter is 20-50nm, and the pressure limit crossed in filter fly is 0.1-0.4MPa, and the scope of the crossflow velocity in filter process is 3-6m/s, obtain filtrate, for subsequent use;
(5) gained filtrate in step (4) is sent into receiver, in receiver, be evaporated to the clear paste of relative density 1.01-1.08 during 60-65 DEG C, obtain clear paste, for subsequent use;
(6) by gained clear paste in step (5) by sodium hydroxide solution adjust ph to 6.0-8.0, embedding is in soda-lime glass tubular oral liquid bottle again, and fill is rolled lid and is placed on 95-98 DEG C of condition, sterilizing 15-18min, warehouse-in is finished product, must treat prostatitic Chinese medicine oral liquid.
Usage: oral, every day 2 times, each 30ml.
Embodiment 3
The present invention treats the preparation of prostatitis Chinese medicine oral liquid, and the weight portion of each raw material is: Caulis Sargentodoxae 28 parts, Cortex Phellodendri 18 parts, Herba Lysimachiae 28 parts, Herba Patriniae 28 parts, Rhizoma Atractylodis 13 parts, Flos Lonicerae 28 parts of, Rhizoma Dioscoreae Septemlobae 18 parts, Semen Coicis 38 parts, Rhizoma Dioscoreae 28 parts, Semen Vaccariae 18 parts, Semen Euryales 18 parts, 28 parts, Poria, Herba Plantaginis core 18 parts, Endoconcha Sepiae 18 parts, 5 parts, Radix Glycyrrhizae;
Be prepared from by following methods:
(1) get raw material Caulis Sargentodoxae, Cortex Phellodendri, Herba Lysimachiae, Herba Patriniae, Rhizoma Atractylodis, Herba Plantaginis core, Endoconcha Sepiae, Radix Glycyrrhizae put into boiling machine, with cold water soak 30-50 minute, then above-mentioned raw materials volume 5-10 soak by water secondary is doubly added, each 2-4 hour, collecting decoction, filters, and collects filtrate, obtain filtrate, for subsequent use;
(2) get raw material Flos Lonicerae, Rhizoma Dioscoreae Septemlobae, Semen Coicis, Rhizoma Dioscoreae, Semen Vaccariae, Semen Euryales, Poria put into boiling machine, with cold water soak 30-50 minute, then add above-mentioned raw materials volume 5-10 soak by water secondary doubly, each 2-4 hour, collecting decoction, filters, collect filtrate, obtain filtrate, for subsequent use;
(3) gained filtrate in gained filtrate in step (1) and step (2) is put into container to be fully uniformly mixed, agitator revolution is 300-500r/min, then the ethanol of 50-80% is added by volume, leave standstill 24-48 hour, filter, filtrate recycling ethanol, refilters, obtain admixing medical solutions, for subsequent use;
(4) gained admixing medical solutions in step (3) is put into ultrafilter to filter, the average pore size scope of the filter membrane of described ultrafilter is 20-50nm, and the pressure limit crossed in filter fly is 0.1-0.4MPa, and the scope of the crossflow velocity in filter process is 3-6m/s, obtain filtrate, for subsequent use;
(5) gained filtrate in step (4) is sent into receiver, in receiver, be evaporated to the clear paste of relative density 1.01-1.08 during 60-65 DEG C, obtain clear paste, for subsequent use;
(6) by gained clear paste in step (5) by sodium hydroxide solution adjust ph to 6.0-8.0, embedding is in soda-lime glass tubular oral liquid bottle again, and fill is rolled lid and is placed on 95-98 DEG C of condition, sterilizing 15-18min, warehouse-in is finished product, must treat prostatitic Chinese medicine oral liquid.
Usage: oral, every day 2 times, each 30ml.
Claims (6)
1. treat a prostatitic Chinese medicine oral liquid, it is characterized in that: be made up of following raw material: Caulis Sargentodoxae 28-32 part, Cortex Phellodendri 18-22 part, Herba Lysimachiae 28-32 part, Herba Patriniae 28-32 part, Rhizoma Atractylodis 13-17 part, Flos Lonicerae 28-32 part, Rhizoma Dioscoreae Septemlobae 18-22 part, Semen Coicis 38-42 part, Rhizoma Dioscoreae 28-32 part, Semen Vaccariae 18-22 part, Semen Euryales 18-22 part, Poria 28-32 part, Herba Plantaginis core 18-22 part, Endoconcha Sepiae 18-22 part, Radix Glycyrrhizae 5-9 part.
2. one according to claim 1 treats prostatitic Chinese medicine oral liquid, it is characterized in that: the weight portion of each raw material is: Caulis Sargentodoxae 30 parts, Cortex Phellodendri 20 parts, Herba Lysimachiae 30 parts, Herba Patriniae 30 parts, Rhizoma Atractylodis 15 parts, Flos Lonicerae 30 parts of, Rhizoma Dioscoreae Septemlobae 20 parts, Semen Coicis 40 parts, Rhizoma Dioscoreae 30 parts, Semen Vaccariae 20 parts, Semen Euryales 20 parts, 30 parts, Poria, Herba Plantaginis core 20 parts, Endoconcha Sepiae 20 parts, 7 parts, Radix Glycyrrhizae.
3. one according to claim 1 treats prostatitic Chinese medicine oral liquid, it is characterized in that: the weight portion of each raw material is: Caulis Sargentodoxae 32 parts, Cortex Phellodendri 22 parts, Herba Lysimachiae 32 parts, Herba Patriniae 32 parts, Rhizoma Atractylodis 17 parts, Flos Lonicerae 32 parts of, Rhizoma Dioscoreae Septemlobae 22 parts, Semen Coicis 42 parts, Rhizoma Dioscoreae 32 parts, Semen Vaccariae 22 parts, Semen Euryales 22 parts, 32 parts, Poria, Herba Plantaginis core 22 parts, Endoconcha Sepiae 22 parts, 9 parts, Radix Glycyrrhizae.
4. one according to claim 1 treats prostatitic Chinese medicine oral liquid, it is characterized in that: the weight portion of each raw material is: Caulis Sargentodoxae 28 parts, Cortex Phellodendri 18 parts, Herba Lysimachiae 28 parts, Herba Patriniae 28 parts, Rhizoma Atractylodis 13 parts, Flos Lonicerae 28 parts of, Rhizoma Dioscoreae Septemlobae 18 parts, Semen Coicis 38 parts, Rhizoma Dioscoreae 28 parts, Semen Vaccariae 18 parts, Semen Euryales 18 parts, 28 parts, Poria, Herba Plantaginis core 18 parts, Endoconcha Sepiae 18 parts, 5 parts, Radix Glycyrrhizae.
5. a kind of preparation method for the treatment of prostatitic Chinese medicine oral liquid according to claim 1 and 2, is characterized in that: be prepared from by following methods:
(1) get raw material Caulis Sargentodoxae, Cortex Phellodendri, Herba Lysimachiae, Herba Patriniae, Rhizoma Atractylodis, Herba Plantaginis core, Endoconcha Sepiae, Radix Glycyrrhizae put into boiling machine, with cold water soak 30-50 minute, then above-mentioned raw materials volume 5-10 soak by water secondary is doubly added, each 2-4 hour, collecting decoction, filters, and collects filtrate, obtain filtrate, for subsequent use;
(2) get raw material Flos Lonicerae, Rhizoma Dioscoreae Septemlobae, Semen Coicis, Rhizoma Dioscoreae, Semen Vaccariae, Semen Euryales, Poria put into boiling machine, with cold water soak 30-50 minute, then add above-mentioned raw materials volume 5-10 soak by water secondary doubly, each 2-4 hour, collecting decoction, filters, collect filtrate, obtain filtrate, for subsequent use;
(3) gained filtrate in gained filtrate in step (1) and step (2) is put into container to be fully uniformly mixed, agitator revolution is 300-500r/min, then the ethanol of 50-80% is added by volume, leave standstill 24-48 hour, filter, filtrate recycling ethanol, refilters, obtain admixing medical solutions, for subsequent use;
(4) gained admixing medical solutions in step (3) is put into ultrafilter to filter, the average pore size scope of the filter membrane of described ultrafilter is 20-50nm, and the pressure limit crossed in filter fly is 0.1-0.4MPa, and the scope of the crossflow velocity in filter process is 3-6m/s, obtain filtrate, for subsequent use;
(5) gained filtrate in step (4) is sent into receiver, in receiver, be evaporated to the clear paste of relative density 1.01-1.08 during 60-65 DEG C, obtain clear paste, for subsequent use;
(6) by gained clear paste in step (5) by sodium hydroxide solution adjust ph to 6.0-8.0, embedding is in soda-lime glass tubular oral liquid bottle again, and fill is rolled lid and is placed on 95-98 DEG C of condition, sterilizing 15-18min, warehouse-in is finished product, must treat prostatitic Chinese medicine oral liquid.
6. a kind of preparation method for the treatment of prostatitic Chinese medicine oral liquid according to claim 1 and 2, is characterized in that: be prepared from by following methods:
(1) get raw material Caulis Sargentodoxae, Cortex Phellodendri, Herba Lysimachiae, Herba Patriniae, Rhizoma Atractylodis, Herba Plantaginis core, Endoconcha Sepiae, Radix Glycyrrhizae put into boiling machine, by cold water soak 30 minutes, then add the soak by water secondary of above-mentioned raw materials volume 10 times, each 2 hours, collecting decoction, filtered, collect filtrate, obtain filtrate, for subsequent use;
(2) get raw material Flos Lonicerae, Rhizoma Dioscoreae Septemlobae, Semen Coicis, Rhizoma Dioscoreae, Semen Vaccariae, Semen Euryales, Poria put into boiling machine, by cold water soak 30 minutes, then add the soak by water secondary of above-mentioned raw materials volume 10 times, each 2 hours, collecting decoction, filtered, collect filtrate, obtain filtrate, for subsequent use;
(3) gained filtrate in gained filtrate in step (1) and step (2) is put into container to be fully uniformly mixed, agitator revolution is 400r/min, then adds the ethanol of 70% by volume, leave standstill 48 hours, filter, filtrate recycling ethanol, refilter, obtain admixing medical solutions, for subsequent use;
(4) gained admixing medical solutions in step (3) is put into ultrafilter to filter, the average pore size of the filter membrane of described ultrafilter is 50nm, and the pressure limit crossed in filter fly is 0.4MPa, and the scope of the crossflow velocity in filter process is 5m/s, obtains filtrate, for subsequent use;
(5) gained filtrate in step (4) is sent into receiver, when being evaporated to 65 DEG C in receiver, the clear paste of relative density 1.08, obtains clear paste, for subsequent use;
(6) by gained clear paste sodium hydroxide solution adjust ph to 6.8 in step (5), embedding is in soda-lime glass tubular oral liquid bottle again, and fill is rolled lid and is placed on 98 DEG C of conditions, sterilizing 15min, warehouse-in is finished product, must treat prostatitic Chinese medicine oral liquid.
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| CN106266580A (en) * | 2016-11-11 | 2017-01-04 | 东莞市百替生物科技有限公司 | A kind of Chinese medicine preparation treating chronic prostatitis and preparation method |
| CN106310085A (en) * | 2016-11-11 | 2017-01-11 | 东莞市百替生物科技有限公司 | Traditional Chinese medicine composition for treating chronic prostatitis and preparation method |
| CN114470144A (en) * | 2022-01-13 | 2022-05-13 | 广西中医药大学附属瑞康医院 | Prostate eliminating soup for inhibiting prostate fibrosis and preparation method thereof |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106266580A (en) * | 2016-11-11 | 2017-01-04 | 东莞市百替生物科技有限公司 | A kind of Chinese medicine preparation treating chronic prostatitis and preparation method |
| CN106310085A (en) * | 2016-11-11 | 2017-01-11 | 东莞市百替生物科技有限公司 | Traditional Chinese medicine composition for treating chronic prostatitis and preparation method |
| CN114470144A (en) * | 2022-01-13 | 2022-05-13 | 广西中医药大学附属瑞康医院 | Prostate eliminating soup for inhibiting prostate fibrosis and preparation method thereof |
| CN114470144B (en) * | 2022-01-13 | 2023-03-31 | 广西中医药大学附属瑞康医院 | Prostate eliminating soup for inhibiting prostate fibrosis and preparation method thereof |
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