CN105213862A - A kind of Chinese medicine composition for the treatment of infantile asthma and preparation method thereof - Google Patents

Abstract

The invention belongs to the field of Chinese medicines, relate to a kind of Chinese medicine composition for the treatment of infantile asthma and preparation method thereof.This Chinese medicine composition is prepared from by the raw material of following parts by weight: Folium Mori 12-30 part, Flos Farfarae 10-26 part, Folium Perillae 14-28 part, Pericarpium Citri Reticulatae 8-22 part, Semen Sinapis Albae 10-18 part, Bulbus Lilii 10-16 part, Rhizoma Arisaematis 6-12 part, Bulbus Fritillariae Cirrhosae 8-16 part, Radix Aneurolepidii 8-14 part and Radix Glycyrrhizae 4-8 part.This Chinese medicine composition has diaphoresis cold expelling, depressed lung-energy dispersing, expelling phlegm for arresting cough, effect of soothing the liver dispelling the stagnated QI and clearing heat and moistening lung, also has that preparation technology is simple, good effect, side effect are low, taking convenience and be easy to advantages such as applying.

Description

A kind of Chinese medicine composition for the treatment of infantile asthma and preparation method thereof

Technical field

The invention belongs to the field of Chinese medicines, particularly relate to a kind of Chinese medicine composition for the treatment of infantile asthma and preparation method thereof.

Background technology

The commonly encountered diseases childhood period that infantile asthma being and frequently-occurring disease are the chronic ill reactive disorders of air flue participated in by the inflammation cells such as eosinophilic granulocyte, mastocyte and T lymphocyte and cytokine.Mostly because of physical weakness, or touch following factor and have the infant of latent phlegm to bring out primary disease to lung: meet sense wind and cold, direct stimulation, depressed, environment cataclysm, inhales people's dust and diet etc.Because development in children is not yet ripe, the low lung of premunition is insufficiency of the spleen weak, clinically shows as intermingling cold and heat, deficiency and excess depositing more.Symptom is: rapid breathing, and suddenly, uncomfortable in chest rough, larynx has asked wheezing sound in outbreak, must not pant put down sleeping.The general outbreak in paroxysmal, or occur agitation, perspiration, expectoration, livid purple, pale complexion, weigh the then symptom such as obnubilation.

Current infantile asthma has western medicine method and treatment by Chinese herbs method.Quick-acting cushion can make asthma attack symptom stop, and eliminates tracheospasm, contributes to breathing.The medicines such as albuterol (being also salbutamol) can be used by nebulizer or metered-dose inhaler.Some controlling medicines also show effect for prevention of asthma.Inhaled steroid is exactly one of them, and energy dephlogistication and swelling, avoid baby to pant.Above-mentioned Western medicine in a short time can effective Control of asthma, but life-time service easily produces drug resistance, even may increase the weight of the state of an illness.How Control of asthma, has become the challenge that China and even the whole world face, and Chinese medicine have action temperature and, onset is lasting and from the feature of basic treatment asthma, become the research and development viewpoint that current asthma medications is new.

Chinese patent application 201310440498.9 discloses a kind of pharmaceutical composition for the treatment of infantile asthma, and this pharmaceutical composition comprises following raw materials: Herba Artemisiae Scopariae, Fructus Gardeniae, Radix Sophorae Flavescentis, Bulbus Fritillariae Thunbergii, Radix Glycyrrhizae, Radix Et Rhizoma Rhei, Flos Matricariae chamomillae.This pharmaceutical composition plays certain clearing away heat-damp and promoting diuresis, the effect of preventing phlegm from forming and stopping coughing, but at diaphoresis cold expelling, depressed lung-energy dispersing aspect effect is not very remarkable.

Summary of the invention

The technical problem to be solved in the present invention is to provide a kind of Chinese medicine composition for the treatment of infantile asthma, this Chinese medicine composition has diaphoresis cold expelling, depressed lung-energy dispersing, expelling phlegm for arresting cough, effect of soothing the liver dispelling the stagnated QI and clearing heat and moistening lung, also have that preparation technology is simple, good effect, side effect be low, taking convenience and be easy to advantages such as applying, in addition, the present invention also provides corresponding manufacturing process to be made under the prerequisite ensureing curative effect by this pharmaceutical composition to facilitate easy-to-use preparation.

Chinese medicine composition of the present invention is prepared from by the raw material of following parts by weight:

Folium Mori 12-30 part, Flos Farfarae 10-26 part, Folium Perillae 14-28 part, Pericarpium Citri Reticulatae 8-22 part, Semen Sinapis Albae 10-18 part, Bulbus Lilii 10-16 part, Rhizoma Arisaematis 6-12 part, Bulbus Fritillariae Cirrhosae 8-16 part, Radix Aneurolepidii 8-14 part and Radix Glycyrrhizae 4-8 part.

Further, described Chinese medicine composition is prepared from by the raw material of following parts by weight:

12 parts, Folium Mori, Flos Farfarae 10 parts, Folium Perillae 14 parts, Pericarpium Citri Reticulatae 8 parts, Semen Sinapis Albae 10 parts, Bulbus Lilii 10 parts, Rhizoma Arisaematis 6 parts, Bulbus Fritillariae Cirrhosae 8 parts, Radix Aneurolepidii 8 parts and 4 parts, Radix Glycyrrhizae.

Further, described Chinese medicine composition is prepared from by the raw material of following parts by weight:

30 parts, Folium Mori, Flos Farfarae 26 parts, Folium Perillae 28 parts, Pericarpium Citri Reticulatae 22 parts, Semen Sinapis Albae 18 parts, Bulbus Lilii 16 parts, Rhizoma Arisaematis 12 parts, Bulbus Fritillariae Cirrhosae 16 parts, Radix Aneurolepidii 14 parts and 8 parts, Radix Glycyrrhizae.

Further, described Chinese medicine composition is prepared from by the raw material of following parts by weight:

20 parts, Folium Mori, Flos Farfarae 18 parts, Folium Perillae 20 parts, Pericarpium Citri Reticulatae 16 parts, Semen Sinapis Albae 14 parts, Bulbus Lilii 14 parts, Rhizoma Arisaematis 8 parts, Bulbus Fritillariae Cirrhosae 12 parts, Radix Aneurolepidii 10 parts and 6 parts, Radix Glycyrrhizae.

Further, described Chinese medicine composition is made into capsule, granule, tablet or pill.

Accordingly, the preparation method of described Chinese medicine composition comprises following step:

S1: take Folium Mori, pulverizes, and crosses 40-60 mesh sieve, obtains coarse powder, coarse powder is sucked air-stream type ultrafine pulverizer and carry out micronizing, and pulverize pressure 0.5MPa, charging rate is 30mg/s, carries out micronizing after drying, crosses 800 mesh sieves, obtains Ultra-fine Powder of Mulberry Leaves;

S2: take Flos Farfarae, Folium Perillae, Pericarpium Citri Reticulatae, Semen Sinapis Albae, Bulbus Lilii, Rhizoma Arisaematis, Bulbus Fritillariae Cirrhosae, Radix Aneurolepidii and Radix Glycyrrhizae, pulverizes, and adds the 10-15 water doubly of medical material gross weight, soak 1-2 hour, reflux, extract, 2-3 time, each 1-3 hour, filter, merging filtrate, is evaporated to the extractum that relative density is 1.20-1.30 at 50-60 DEG C, cooling, slowly add ethanol while stirring and reach 40-60% to alcohol content, 4 DEG C of standing 12-24 hour, filter and retain filtering residue, obtain filtrate A;

S3: slowly adding its weight 4-6 times amount volume fraction in the filtering residue that S2 obtains while stirring is the ethanol of 40-60%, 4 DEG C of standing 3-5 hour, filters, obtains liquor B and filtering residue; Filtering residue uses the washing with alcohol 2-3 time of 40-60% again, collects and merges cleaning mixture;

S4: merge described filtrate A, liquor B and cleaning mixture, surveys extractum that relative density be 1.20-1.30 under being evaporated to 60 DEG C of conditions after mixing;

S5: the extractum drying under reduced pressure obtained by S4, pulverize, cross 100-200 mesh sieve, add described Ultra-fine Powder of Mulberry Leaves, mixing, obtains Chinese medicine composition powder.

Source, the nature and flavor of the present invention's component used, return through and effect:

Folium Mori: this product is the dried leaves of moraceae plants Mulberry; Sweet in the mouth, hardship, cold in nature; Return lung, Liver Channel; Dispelling wind and heat pathogens, clearing away lung-heat and moistening for dryness, liver heat removing and eyesight improving.

Flos Farfarae: this product is the dry flower of feverfew coltsfoot; Acrid in the mouth, micro-hardship, warm in nature; Return lung meridian; Nourishing the lung to keep the adverse QI downward, relieving cough and resolving phlegm.

Folium Perillae: this product is the dried leaves of labiate Folium Perillae; Acrid in the mouth, warm in nature; Return lung, spleen channel; Induce sweat cold expelling, relieving QI stagnancy in the stomach.

Pericarpium Citri Reticulatae: this product is the dry peel of rutaceae orange; Bitter in the mouth, pungent, warm in nature; Return lung, spleen channel; Regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.

Semen Sinapis Albae: this product is the seed of crucifer Caulis et Folium Sinapis albee; Acrid in the mouth, warm in nature; Return lung, liver, spleen, stomach, pericardium channel; Reduce phlegm by drink, mass dissipating and swelling eliminating.

Bulbus Lilii: this product is the dry meat scale leaf of liliaceous plant tiger lily, Bulbus Lilii or Lilium tenuifolium; Sweet in the mouth, cold in nature; GUIXIN, lung meridian; Nourishing YIN and moistening the lung, clearing away heart-fire for tranquillization.

Rhizoma Arisaematis: this product is the dry tuber of aroid Rhizoma Arisaematis; Bitter in the mouth, pungent, warm in nature; Return lung, liver, spleen channel; Drying dampness to eliminate phlegm, expellings wind and relieving convulsion, mass dissipating and swelling eliminating.

Bulbus Fritillariae Cirrhosae: this product is the dry bulb of liliaceous plant Bulbus Fritillariae Cirrhosae; Bitter in the mouth, sweet, cold nature; Return lung, heart channel; Clearing heat and moistening lung, preventing phlegm from forming and stopping coughing.

Radix Aneurolepidii: this product is root or the herb that grass relies grass; Sweet in the mouth, micro-hardship, cold in nature; Return lung meridian; Clearing away heat-damp and promoting diuresis, relievings asthma, hemostasis.

Radix Glycyrrhizae: this product is the dry root of glycyrrhizic legume, Glycyrrhiza inflata Bat. or Glycyrrhiza glabra L.; Sweet in the mouth, property is put down; GUIXIN, lung, spleen, stomach warp; Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.

The prescription analysis of Chinese medicine of the present invention:

According to the compatibility theory of the traditional Chinese medical science to the dialectical and Chinese crude drug for the treatment of infantile asthma disease, in conjunction with the body constitution of modern and the feature of modern pharmaceutical technology, the collocation ingredients of reasonable science, forms Chinese prescription of the present invention.Prescription of the present invention is with Folium Mori and Flos Farfarae for monarch drug, clearing away lung-heat and moistening for dryness, relieving cough and resolving phlegm; With Folium Perillae, Bulbus Lilii and Bulbus Fritillariae Cirrhosae for ministerial drug, relieving QI stagnancy in the stomach, nourishing YIN and moistening the lung; With Semen Sinapis Albae, Rhizoma Arisaematis, Pericarpium Citri Reticulatae and Radix Aneurolepidii for adjuvant drug, reduce phlegm by drink, expelling wind and relieving convulsion, drying dampness to eliminate phlegm; With Radix Glycyrrhizae for making medicine, invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, relieving spasm to stop pain; The all medicines of monarch coordinate, and collaborative promotion, complements each other, finally reach preventing phlegm from forming and stopping coughing, clearing heat and moistening lung, the effects such as regulating qi-flowing for strengthening spleen, thus have very significant therapeutic effect to infantile asthma disease.

Compared with prior art, the present invention has following technical advantage:

1, Chinese medicine composition of the present invention is compared with the common drug of existing other treatment infantile asthma, and at diaphoresis cold expelling, depressed lung-energy dispersing, expelling phlegm for arresting cough, the aspects such as soothing the liver dispelling the stagnated QI and clearing heat and moistening lung have more remarkable efficacy.

2, compared with the chemicals of Current therapeutic infantile asthma, Chinese medicine composition of the present invention is natural pure Chinese medicinal preparation, and untoward reaction and side effect significantly reduce, and Chinese medicine composition effect of the present invention is comprehensive, medication effect is better, efficiently solves the morbidity root of infantile asthma.

3, Chinese medicine composition of the present invention also has that compatibility science, preparation technology are simple, good effect, side effect are low, taking convenience and be easy to advantages such as applying.

Detailed description of the invention

It will be understood by those skilled in the art that technology disclosed in following examples represents the technology playing good action in the practice of the invention of the present inventor's discovery.But, many changes can be made in disclosed specific embodiments, and still obtain same or analogous result, and not depart from the spirit and scope of the present invention.

embodiment 1

The embodiment of the present invention 1 Chinese medicine composition is prepared from by the raw material of following parts by weight:

12 parts, Folium Mori, Flos Farfarae 10 parts, Folium Perillae 14 parts, Pericarpium Citri Reticulatae 8 parts, Semen Sinapis Albae 10 parts, Bulbus Lilii 10 parts, Rhizoma Arisaematis 6 parts, Bulbus Fritillariae Cirrhosae 8 parts, Radix Aneurolepidii 8 parts and 4 parts, Radix Glycyrrhizae.

Preparation method is as follows:

S1: take Folium Mori, pulverizes, and crosses 40-60 mesh sieve, obtains coarse powder, coarse powder is sucked air-stream type ultrafine pulverizer and carry out micronizing, and pulverize pressure 0.5MPa, charging rate is 30mg/s, carries out micronizing after drying, crosses 800 mesh sieves, obtains Ultra-fine Powder of Mulberry Leaves;

S2: take Flos Farfarae, Folium Perillae, Pericarpium Citri Reticulatae, Semen Sinapis Albae, Bulbus Lilii, Rhizoma Arisaematis, Bulbus Fritillariae Cirrhosae, Radix Aneurolepidii and Radix Glycyrrhizae, pulverizes, and adds the 10-15 water doubly of medical material gross weight, soak 1-2 hour, reflux, extract, 2-3 time, each 1-3 hour, filter, merging filtrate, is evaporated to the extractum that relative density is 1.20-1.30 at 50-60 DEG C, cooling, slowly add ethanol while stirring and reach 40-60% to alcohol content, 4 DEG C of standing 12-24 hour, filter and retain filtering residue, obtain filtrate A;

S3: slowly adding its weight 4-6 times amount volume fraction in the filtering residue that S2 obtains while stirring is the ethanol of 40-60%, 4 DEG C of standing 3-5 hour, filters, obtains liquor B and filtering residue; Filtering residue uses the washing with alcohol 2-3 time of 40-60% again, collects and merges cleaning mixture;

S4: merge described filtrate A, liquor B and cleaning mixture, surveys extractum that relative density be 1.20-1.30 under being evaporated to 60 DEG C of conditions after mixing;

S5: the extractum drying under reduced pressure obtained by S4, pulverize, cross 100-200 mesh sieve, add described Ultra-fine Powder of Mulberry Leaves, mixing, obtains Chinese medicine composition powder;

S6: get described Chinese medicine composition fine powder 1 part, cane sugar powder 3 parts, 1.25 parts, dextrin and appropriate amount of ethanol, mixing, dry, pulverize into fine powder, incapsulates in shell, obtain the capsule of Chinese medicine composition.

embodiment 2

The embodiment of the present invention 2 Chinese medicine composition is prepared from by the raw material of following parts by weight:

30 parts, Folium Mori, Flos Farfarae 26 parts, Folium Perillae 28 parts, Pericarpium Citri Reticulatae 22 parts, Semen Sinapis Albae 18 parts, Bulbus Lilii 26 parts, Rhizoma Arisaematis 12 parts, Bulbus Fritillariae Cirrhosae 16 parts, Radix Aneurolepidii 14 parts and 8 parts, Radix Glycyrrhizae.

Preparation method is as follows:

S1: take Folium Mori, pulverizes, and crosses 40-60 mesh sieve, obtains coarse powder, coarse powder is sucked air-stream type ultrafine pulverizer and carry out micronizing, and pulverize pressure 0.5MPa, charging rate is 30mg/s, carries out micronizing after drying, crosses 800 mesh sieves, obtains Ultra-fine Powder of Mulberry Leaves;

S2: take Flos Farfarae, Folium Perillae, Pericarpium Citri Reticulatae, Semen Sinapis Albae, Bulbus Lilii, Rhizoma Arisaematis, Bulbus Fritillariae Cirrhosae, Radix Aneurolepidii and Radix Glycyrrhizae, pulverizes, and adds the 10-15 water doubly of medical material gross weight, soak 1-2 hour, reflux, extract, 2-3 time, each 1-3 hour, filter, merging filtrate, is evaporated to the extractum that relative density is 1.20-1.30 at 50-60 DEG C, cooling, slowly add ethanol while stirring and reach 40-60% to alcohol content, 4 DEG C of standing 12-24 hour, filter and retain filtering residue, obtain filtrate A;

S3: slowly adding its weight 4-6 times amount volume fraction in the filtering residue that S2 obtains while stirring is the ethanol of 40-60%, 4 DEG C of standing 3-5 hour, filters, obtains liquor B and filtering residue; Filtering residue uses the washing with alcohol 2-3 time of 40-60% again, collects and merges cleaning mixture;

S4: merge described filtrate A, liquor B and cleaning mixture, surveys extractum that relative density be 1.20-1.30 under being evaporated to 60 DEG C of conditions after mixing;

S5: the extractum drying under reduced pressure obtained by S4, pulverize, cross 100-200 mesh sieve, add described Ultra-fine Powder of Mulberry Leaves, mixing, obtains Chinese medicine composition powder;

S6: get described Chinese medicine composition fine powder 1 part, cane sugar powder 3 parts, 1.25 parts, dextrin and appropriate amount of ethanol, soft material processed, crosses 16 mesh sieve granules, dry, obtains the granule of Chinese medicine composition.

embodiment 3

The embodiment of the present invention 3 Chinese medicine composition is prepared from by the raw material of following parts by weight:

20 parts, Folium Mori, Flos Farfarae 18 parts, Folium Perillae 20 parts, Pericarpium Citri Reticulatae 16 parts, Semen Sinapis Albae 14 parts, Bulbus Lilii 14 parts, Rhizoma Arisaematis 8 parts, Bulbus Fritillariae Cirrhosae 12 parts, Radix Aneurolepidii 10 parts and 6 parts, Radix Glycyrrhizae.

Preparation method is similar to Example 2.

clinical observation on the therapeutic effect

1, case selection: in 360 routine infantile asthma clinical patients volunteers, boy patient 180 example, young girl patient 180 example, age bracket be 4-12 year, all patients all has typical symptoms of asthma, and in sex, age, the course of disease no difference of science of statistics.

2, diagnostic criteria:

(1) tcm diagnosis standard: formulate according to " TCM syndrome diagnostic criteria " content relevant in " Chinese medical disease Standardization of diagnosis and curative effect ", " new Chinese medicine clinical guidance principle " (2002) and " the senior book series Pediatrics of Chinese Medicine of Chinese medicine " (second edition) " asthma " that State Administration of Traditional Chinese Medicine issues:

Primary symptom: cough with asthma is out of breath, wheezing in larynx, expectoration thickness.

Secondary disease: heating, nausea and vomiting, poor appetite, abdominal distention, constipation or sticky, yellowish or reddish urine.

Tongue fur pulse condition: red tongue, thick and greasy fur, slippery and rapid pulse, or fingerprint is purple.

In above-mentioned standard, need possess primary symptom 2, secondary disease more than 2, tongue fur is indispensable, and diagnosable is damp and hot asthma.

(2) Western medicine diagnose standard: " children with asthma diagnosis and treatment guide " according to the revision in 2008 of department of pediatrics branch of Chinese Medical Association pneumatology group:

1. recurrent exerbation pant, cough, tachypnea, uncomfortable in chest, many with contact allergen, cold air, physics, chemical irritation, respiratory tract infection and motion etc. relevant, be everlasting night and (or) early morning show effect or aggravate;

2. during outbreak at two lung audible and be dispersed in or diffusivity, the wheezing sound based on expiratory phase, expiratory phase prolongation;

3. above-mentioned symptom and the sign effective or spontaneous remission through asthma treatment;

Panting 4. caused by other diseases, cough, tachypnea and breast vexed;

5. its atypical clinical manifestations person's (as without obviously panting or wheezing sound), at least should possess following 1: A, brinchial provocation test or motion activated test positive; B, alleged occurrence reversible airflow limitation; C, maximal expiratory flow (PEF) aberration rate every day (monitoring 1 ~ 2 week continuously) are higher than 20%.Meet 1. ~ 4. article or 4., 5. article person, can asthma be diagnosed as.

3, exclusion standard: 1. do not meet diagnostic criteria and inclusive criteria person; 2. the serious heart, liver, kidney, lung disease or congenital diseases are had; 3. severity is the children with bronchial asthma disease of severe and the person that occurs severe attack after including in; 4. to institute medicine allergy sufferers.

4, efficacy assessment standard: according to " new Chinese medicine guideline of clinical investigations ":

Clinic control: symptoms of asthma complete incidence graph, even if there is mild episode not need medication to alleviate once in a while;

Effective: obviously to alleviate before asthma attack comparatively, still need with glucocorticoid or bronchodilator;

Take a turn for the better: symptoms of asthma alleviates to some extent, still needs with glucocorticoid or bronchodilator;

Invalid: clinical symptoms is without improvement or increase the weight of on the contrary;

Total effective rate=(clinic control+effective+improvement)/total number of cases × 100%.

5, instructions of taking: 360 patient volunteers are divided into 3 groups at random, often organize 120 people, be respectively treatment A group, treatment B group and matched group, treatment A group, treatment B component do not take capsule preparations that the embodiment of the present invention 1 prepares and the granular preparation that embodiment 2 prepares, every day 3 times, each 1-2g, serve on 1 month.Matched group takes salbutamol sheet (Shanxi Yun Peng pharmaceutical Co. Ltd), and each 1-2 sheet, 3 times on the one, serve on 1 month.

6, therapeutic outcome: as shown in table 1.

table 1 therapeutic outcome

This test adopts salbutamol sheet as a control group, by comparing with the therapeutic effect of Chinese medicine composition of the present invention, can find out the curative effect of traditional Chinese medicine composition for treating infantile asthma of the present invention.The clinic control rate of Chinese medicine composition of the present invention reaches more than 80%, and total effective rate reaches more than 90%, higher than clinic control rate and the total effective rate of matched group, wherein best with the therapeutic effect for the treatment of A group.Visible, the good effect of Chinese medicine composition of the present invention, clinic control rate is high, can be used as the drug use for the treatment of infantile asthma.

Owing to describing the present invention by above preferred embodiment, in spirit of the present invention and/or scope, any for replacement/of the present invention or combination implement the present invention, be all apparent for a person skilled in the art, and be included among the present invention.

Claims (6)

1. treat a Chinese medicine composition for infantile asthma, it is characterized in that, be prepared from by the raw material of following parts by weight:

Folium Mori 12-30 part, Flos Farfarae 10-26 part, Folium Perillae 14-28 part, Pericarpium Citri Reticulatae 8-22 part, Semen Sinapis Albae 10-18 part, Bulbus Lilii 10-16 part, Rhizoma Arisaematis 6-12 part, Bulbus Fritillariae Cirrhosae 8-16 part, Radix Aneurolepidii 8-14 part and Radix Glycyrrhizae 4-8 part.

2. the Chinese medicine composition for the treatment of infantile asthma as claimed in claim 1, is characterized in that, be prepared from by the raw material of following parts by weight:

12 parts, Folium Mori, Flos Farfarae 10 parts, Folium Perillae 14 parts, Pericarpium Citri Reticulatae 8 parts, Semen Sinapis Albae 10 parts, Bulbus Lilii 10 parts, Rhizoma Arisaematis 6 parts, Bulbus Fritillariae Cirrhosae 8 parts, Radix Aneurolepidii 8 parts and 4 parts, Radix Glycyrrhizae.

3. the Chinese medicine composition for the treatment of infantile asthma as claimed in claim 1, is characterized in that, be prepared from by the raw material of following parts by weight:

30 parts, Folium Mori, Flos Farfarae 26 parts, Folium Perillae 28 parts, Pericarpium Citri Reticulatae 22 parts, Semen Sinapis Albae 18 parts, Bulbus Lilii 16 parts, Rhizoma Arisaematis 12 parts, Bulbus Fritillariae Cirrhosae 16 parts, Radix Aneurolepidii 14 parts and 8 parts, Radix Glycyrrhizae.

4. the Chinese medicine composition for the treatment of infantile asthma as claimed in claim 1, is characterized in that, be prepared from by the raw material of following parts by weight:

20 parts, Folium Mori, Flos Farfarae 18 parts, Folium Perillae 20 parts, Pericarpium Citri Reticulatae 16 parts, Semen Sinapis Albae 14 parts, Bulbus Lilii 14 parts, Rhizoma Arisaematis 8 parts, Bulbus Fritillariae Cirrhosae 12 parts, Radix Aneurolepidii 10 parts and 6 parts, Radix Glycyrrhizae.

5. the Chinese medicine composition of the treatment infantile asthma as described in any one of claim 1-4, is characterized in that, described Chinese medicine composition is made into capsule, granule, tablet or pill.

6. the preparation method of the Chinese medicine composition of the treatment infantile asthma as described in any one of claim 1-4, is characterized in that, comprises following step:

S1: take Folium Mori, pulverizes, and crosses 40-60 mesh sieve, obtains coarse powder, coarse powder is sucked air-stream type ultrafine pulverizer and carry out micronizing, and pulverize pressure 0.5MPa, charging rate is 30mg/s, carries out micronizing after drying, crosses 800 mesh sieves, obtains Ultra-fine Powder of Mulberry Leaves;

S2: take Flos Farfarae, Folium Perillae, Pericarpium Citri Reticulatae, Semen Sinapis Albae, Bulbus Lilii, Rhizoma Arisaematis, Bulbus Fritillariae Cirrhosae, Radix Aneurolepidii and Radix Glycyrrhizae, pulverizes, and adds the 10-15 water doubly of medical material gross weight, soak 1-2 hour, reflux, extract, 2-3 time, each 1-3 hour, filter, merging filtrate, is evaporated to the extractum that relative density is 1.20-1.30 at 50-60 DEG C, cooling, slowly add ethanol while stirring and reach 40-60% to alcohol content, 4 DEG C of standing 12-24 hour, filter and retain filtering residue, obtain filtrate A;

S3: slowly adding its weight 4-6 times amount volume fraction in the filtering residue that S2 obtains while stirring is the ethanol of 40-60%, 4 DEG C of standing 3-5 hour, filters, obtains liquor B and filtering residue; Filtering residue uses the washing with alcohol 2-3 time of 40-60% again, collects and merges cleaning mixture;

S4: merge described filtrate A, liquor B and cleaning mixture, surveys extractum that relative density be 1.20-1.30 under being evaporated to 60 DEG C of conditions after mixing;

S5: the extractum drying under reduced pressure obtained by S4, pulverize, cross 100-200 mesh sieve, add described Ultra-fine Powder of Mulberry Leaves, mixing, obtains Chinese medicine composition powder.