CN105213421A - A kind of rinsing the mouth medicated bag for the treatment of buccal cavity fungal infection and preparation method thereof - Google Patents
A kind of rinsing the mouth medicated bag for the treatment of buccal cavity fungal infection and preparation method thereof Download PDFInfo
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- CN105213421A CN105213421A CN201510666341.7A CN201510666341A CN105213421A CN 105213421 A CN105213421 A CN 105213421A CN 201510666341 A CN201510666341 A CN 201510666341A CN 105213421 A CN105213421 A CN 105213421A
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Abstract
The invention discloses a kind of rinsing the mouth medicated bag for the treatment of buccal cavity fungal infection and preparation method thereof, belong to health technology field.It comprises the tablet being used for the treatment of buccal cavity fungal infection, and described tablet is wrapped with the medicated bag for extend tablet time of staying in the oral cavity, and described medicated bag is made up of degreasing cotton gauze, and by linear sealing, described medicated bag is also connected with the spun yarn rope being convenient to pull.Rinsing the mouth medicated bag of the present invention, the problem of oral cavity muscle sleepiness when can solve rinsing the mouth, prolong drug action time in the oral cavity, prevent medicine from being removed by saliva in oral cavity, and can cleaning oral cavity, reach the effect of effectively treatment buccal cavity fungal infection, can use in different environments, both be applicable to the patient of Consciousness, and be also applicable to the patient of unconsciousness, there is the advantages such as efficient, safe, easy to operate, convenient, comfortable.
Description
Technical field
The present invention relates to a kind of rinsing the mouth medicated bag for the treatment of buccal cavity fungal infection and preparation method thereof, belong to health technology field.
Background technology
The optimum growth conditions of fungus is temperature 22 ~ 36 DEG C, humidity 95 ~ 100%, pH5 ~ 6.5.Chemicotherapy is while killing tumor cell, and can directly destroy oral mucosa barrier, oral cavity self-cleaning action weakens, and causes the impaired formation ulcer of oral mucosa and causes infection.For a long time, Reusability high-efficiency broad spectrum antibiotic, hormone, and the easily secondary buccal cavity fungal infection (Xu Lili such as the body constitution of patient and nutriture difference, what monarch of Wu Qiong, 4 kinds of collutory suppress the experimentation of oral cavity bacterium effect. Chinese Quotation Analysis [J], 2012,28 (34): 79-81).
Nystatin and sodium bicarbonate is often adopted to treat buccal cavity fungal infection (Song Hongyan at present clinically, Wang Yu, He Rongrong. the observation of curative effect [J] of Chinese medicine external treatment infant thrush. Practical oral medical journal, 2015,31 (1): 125-126).Sodium bicarbonate can improve oral environment pH value, ergosterol effect in nystatin and fungal cell membrane, make ionic pump dysfunction and the reversible lesion of film, low concentration is bacteriostasis, and high concentration is bactericidal action (Liu new people, Xu Taoyuan, Zhang Keyi etc. practical clinical treatment medicine [M]. Liaoning science and technology goes out society, 2003,1st edition, 708-709).
Mouth care comprises the multiple methods such as rinsing the mouth, scouring, flushing, and sanity person is rinsing the mouth, and stupor person is for cleaning, wherein rinsing the mouth is the most conventional, adopt collutory 10 ~ 15mL rinsing the mouth, 2 ~ 3min/ time, then spue, 2 ~ 3 times repeatedly, 4 times/d, respectively at 30min after the meal and rinsing the mouth 5min before sleeping (Li Xiaojuan. Novel dental nursing liquid application clinically [J]. Chinese Quotation Analysis, 2011,4,27th volume supplementary issue).
Malaise symptoms main manifestations during patient's mouth nursing is felt sick, cough, oral cavity muscle is tired, and according to statistics, the tolerance time of patient per's rinsing the mouth is 2.30 ± 0.316min.There are the following problems for existing mouth care: during patient's mouth rinsing the mouth, muscle is easily tired, and the rinsing the mouth time is short, and drug treating time is short, does not reach therapeutic effect; Medicine is removed by saliva in oral cavity; Need frequently to tell collutory, be not suitable for implementing at multiple environment; The patient being confined to Consciousness uses.
In sum, in the urgent need to a kind of both can cosily prolong drug action time in the oral cavity, to reduce oral cavity muscle tired, there is cleaning action again, be both applicable to conscious patient, be also applicable to the effective ways of the treatment buccal cavity fungal infection of the patient of unconsciousness.
Summary of the invention
The object of the invention is to solve the deficiencies in the prior art, a kind of rinsing the mouth medicated bag for the treatment of buccal cavity fungal infection and preparation method thereof is provided.Rinsing the mouth medicated bag of the present invention, the problem of oral cavity muscle sleepiness when can solve rinsing the mouth, prolong drug action time in the oral cavity, prevent medicine from being removed by saliva in oral cavity, and can cleaning oral cavity, reach the effect of effectively treatment buccal cavity fungal infection, can use in different environments, both be applicable to the patient of Consciousness, and be also applicable to the patient of unconsciousness, there is the advantages such as efficient, safe, easy to operate, convenient, comfortable.
The technical scheme that the present invention solves the problems of the technologies described above is as follows: a kind of rinsing the mouth medicated bag for the treatment of buccal cavity fungal infection, comprise the tablet being used for the treatment of buccal cavity fungal infection, described tablet is wrapped with the medicated bag for extend tablet time of staying in the oral cavity, described medicated bag is made up of degreasing cotton gauze, and by linear sealing, described medicated bag is also connected with the spun yarn rope being convenient to pull.
On the basis of technique scheme, the present invention can also do following improvement.
Further, described medicated bag (1) is made up of degreasing cotton gauze (3) doubling, described tablet (2) is positioned at the centre of described medicated bag (1), and respectively there are 8 layers of degreasing cotton gauze (3) described tablet (2) both sides.
Further, the length of described spun yarn rope (4) is greater than the half of the transverse width of described degreasing cotton gauze (3).
Further, described tablet comprises the raw material of following dosage: the nystatin sheet half of 500,000 units and the Sodium Bicarbonate Tablets half of 0.5g.
Treat a manufacture method for the rinsing the mouth medicated bag of buccal cavity fungal infection, comprise the steps:
(1) medicated bag is prepared: get 1 piece of rectangular degreasing cotton gauze (3), vertical along midline doubling 1 time, launch, by two edge center lines respectively to interior doubling, then laterally along midline doubling, launch, by two edge center lines respectively to interior doubling, put a spun yarn rope (4) in the midline of transverse direction, pass as frenulum, more laterally along midline doubling 1 time, finally vertical along midline doubling 1 time, sew up the both sides of 2 wireless openings with line (5), obtain medicated bag (1), sterilizing;
(2) tablet taking (2), loads in the medicated bag after step (1) sterilizing, by spun yarn rope (4) two ends to drawing, and tightening pocket opening;
(3) with the medicated bag (1) of water-soaked step (2) tightening pocket opening, patient oral cavity is put into, by outside spun yarn rope (4) indwelling oral cavity, rinsing the mouth.
On the basis of technique scheme, the present invention can also do following improvement.
Further, the length of step (1) described spun yarn rope (4) is greater than the half of the transverse width of described degreasing cotton gauze (3).
Further, step (2) described tablet comprises the raw material of following dosage: the nystatin sheet half of 500,000 units and the Sodium Bicarbonate Tablets half of 0.5g.
Further, the time of step (3) described rinsing the mouth is 10 ~ 30 minutes/time, 3 ~ 5 times/day.
In the present invention, during rinsing the mouth, the medicated bag that tablet is housed can be changed in oral cavity different parts and rotate containing changing, also can adjust the rinsing the mouth time according to patient tolerance; Not tolerant saliva can be spued during rinsing the mouth, also medicinal liquid can be swallowed health without impact; Frenulum can be placed on outside oral cavity by patient, also frenulum can be wiped out again containing changing; The patient that unconsciousness, oral cavity muscle are unable, then soak with warm boiled water, increases tablet dissolution velocity, and be advisable gently to twist not water outlet, the frenulum of medicated bag ties up to clothes button place and fixes, and prevents from swallowing.
The invention has the beneficial effects as follows:
1. rinsing the mouth medicated bag of the present invention, the problem of oral cavity muscle sleepiness when can solve rinsing the mouth, prolong drug action time in the oral cavity, prevents medicine from being removed by saliva in oral cavity, and can cleaning oral cavity, reaches the effect of effectively treatment buccal cavity fungal infection.
2. rinsing the mouth medicated bag of the present invention, can use in different environments, is both applicable to the patient of Consciousness, is also applicable to the patient of unconsciousness, has the advantages such as efficient, safe, easy to operate, convenient, comfortable.
3. the medicated bag of rinsing the mouth medicated bag of the present invention is when making, and adopts inwardly folding mode, the limit yarn of degreasing cotton gauze can be avoided to be shed in oral cavity, safety and sanitation more.
4. preparation method of the present invention is simple, and cost is low, the market demand is extensive.
Accompanying drawing explanation
Fig. 1 is overall structure schematic diagram of the present invention.
Fig. 2 is the structural representation of degreasing cotton gauze of the present invention.
Fig. 3 is the structural representation of Fig. 2 vertically after midline doubling 1 time.
Fig. 4 is that Fig. 3 launches rear two edge center lines respectively to the structural representation after interior doubling.
Fig. 5 is the structural representation of Fig. 4 laterally after midline doubling 1 time.
Fig. 6 is the structural representation of two edge center lines respectively to interior doubling and after placing spun yarn rope after Fig. 5 launches.
Fig. 7 is the structural representation that Fig. 6 to place after spun yarn rope more laterally after midline doubling 1 time.
Fig. 8 is the structural representation of Fig. 7 vertically after midline doubling 1 time.
In accompanying drawing, the list of parts representated by each label is as follows:
1, medicated bag, 2, tablet, 3, degreasing cotton gauze, 4, spun yarn rope, 5, line.
Detailed description of the invention
Be described principle of the present invention and feature below in conjunction with accompanying drawing, example, only for explaining the present invention, is not intended to limit scope of the present invention.
Embodiment 1
As shown in Figure 1, a kind of rinsing the mouth medicated bag for the treatment of buccal cavity fungal infection, comprise the tablet 2 being used for the treatment of buccal cavity fungal infection, described tablet is wrapped with the medicated bag 1 for extend tablet 2 time of staying in the oral cavity, described medicated bag 1 is made up of degreasing cotton gauze 3, and sealed by line 5, described medicated bag 1 is also connected with the spun yarn rope 4 being convenient to pull.
Described medicated bag 1 is made up of degreasing cotton gauze 3 doubling, and described tablet 2 is positioned at the centre of described medicated bag 1, and respectively there are 8 layers of degreasing cotton gauze 3 described tablet 2 both sides.
The length of described spun yarn rope 4 is greater than the half of the transverse width of described degreasing cotton gauze 3.
Described tablet 2 comprises the raw material of following dosage: the nystatin sheet half of 500,000 units and the Sodium Bicarbonate Tablets half of 0.5g.
Treat a manufacture method for the rinsing the mouth medicated bag of buccal cavity fungal infection, comprise the steps:
(1) medicated bag is prepared: the rectangular degreasing cotton gauze 3 (as shown in Figure 2) getting 1 piece of 12 × 10cm, vertical along midline doubling 1 time (as shown in Figure 3), launch, by two edge center lines respectively to interior doubling (as shown in Figure 4), then laterally along midline doubling (as shown in Figure 5), launch, by two edge center lines respectively to interior doubling, a spun yarn rope 4 is put in the midline of transverse direction, pass as frenulum (as shown in Figure 6), again laterally along midline doubling 1 time (as shown in Figure 7), finally vertical along midline doubling 1 time (as shown in Figure 8), the both sides of 2 wireless openings are sewed up with line 5, obtain the small gauze bag medicated bag 1 of 3 × 2.5cm of 16 thickness, sterilizing,
(2) get the nystatin sheet half 2 of 500,000 units and the Sodium Bicarbonate Tablets half 2 of 0.5g, load in the medicated bag after step (1) sterilizing, by spun yarn rope 4 two ends to drawing, tightening pocket opening (as shown in Figure 1);
(3) with the medicated bag 1 of warm water soaking step (2) tightening pocket opening, be advisable gently to twist not water outlet, put into the patient oral cavity that unconsciousness, oral cavity muscle are unable, by outside cord indwelling oral cavity, frenulum is tied up to clothes button place to fix, prevent from medicated bag 1 to swallow, rinsing the mouth, the rinsing the mouth time is 10 ~ 30 minutes/time, 3 ~ 5 times/day.
Embodiment 2
As shown in Figure 1, a kind of rinsing the mouth medicated bag for the treatment of buccal cavity fungal infection, comprise the tablet 2 being used for the treatment of buccal cavity fungal infection, described tablet is wrapped with the medicated bag 1 for extend tablet 2 time of staying in the oral cavity, described medicated bag 1 is made up of degreasing cotton gauze 3, and sealed by line 5, described medicated bag 1 is also connected with the spun yarn rope 4 being convenient to pull.
Described medicated bag 1 is made up of degreasing cotton gauze 3 doubling, and described tablet 2 is positioned at the centre of described medicated bag 1, and respectively there are 8 layers of degreasing cotton gauze 3 described tablet 2 both sides.
The length of described spun yarn rope 4 is greater than the half of the transverse width of described degreasing cotton gauze 3.
Described tablet 2 comprises the raw material of following dosage: the nystatin sheet half of 500,000 units and the Sodium Bicarbonate Tablets half of 0.5g.
Treat a manufacture method for the rinsing the mouth medicated bag of buccal cavity fungal infection, comprise the steps:
(1) medicated bag is prepared: the rectangular degreasing cotton gauze 3 (as shown in Figure 2) getting 1 piece of 18 × 12cm, vertical along midline doubling 1 time (as shown in Figure 3), launch, by two edge center lines respectively to interior doubling (as shown in Figure 4), then laterally along midline doubling (as shown in Figure 5), launch, by two edge center lines respectively to interior doubling, a spun yarn rope 4 is put in the midline of transverse direction, pass as frenulum (as shown in Figure 6), again laterally along midline doubling 1 time (as shown in Figure 7), finally vertical along midline doubling 1 time (as shown in Figure 8), the both sides of 2 wireless openings are sewed up with line 5, obtain the small gauze bag medicated bag 1 of 4.5 × 3cm of 16 thickness, sterilizing,
(2) get the nystatin sheet half 2 of 500,000 units and the Sodium Bicarbonate Tablets half 2 of 0.5g, load in the medicated bag after step (1) sterilizing, by spun yarn rope 4 two ends to drawing, tightening pocket opening (as shown in Figure 1);
(3) with the medicated bag 1 of cold water soaking step (2) tightening pocket opening, be advisable gently to twist not water outlet, cord knotting cut off, medicated bag is put into the patient oral cavity of Consciousness, rinsing the mouth, the rinsing the mouth time is 10 ~ 30 minutes/time, 3 ~ 5 times/day.
Experimental example
Clinical experiment, suffers from severe drug rash because there are 80 routine patients of buccal cavity fungal infection with heavy dose of hormone therapy, random point experimental group and each 40 examples of matched group.Experimental group adopts rinsing the mouth medicated bag of the present invention to carry out rinsing the mouth, and matched group adopts traditional antifungal collutory to carry out rinsing the mouth, and matched group is the rinsing the mouth frequency of experimental group 2 ~ 3 times, two groups of healing times: experimental group 4 ± 1.50 days, matched group 12+3.50 days.As can be seen here, adopt rinsing the mouth medicated bag of the present invention, the treatment time of buccal cavity fungal infection can be shortened, there is the effect of significantly treatment buccal cavity fungal infection.
The foregoing is only preferred embodiment of the present invention, not in order to limit the present invention, within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (8)
1. treat the rinsing the mouth medicated bag of buccal cavity fungal infection for one kind, it is characterized in that, comprise the tablet (2) being used for the treatment of buccal cavity fungal infection, described tablet is wrapped with the medicated bag (1) for extend tablet (2) time of staying in the oral cavity, described medicated bag (1) is made up of degreasing cotton gauze (3), and by line (5) sealing, described medicated bag (1) is also connected with the spun yarn rope (4) being convenient to pull.
2. a kind of rinsing the mouth medicated bag for the treatment of buccal cavity fungal infection according to claim 1, it is characterized in that, described medicated bag (1) is made up of degreasing cotton gauze (3) doubling, described tablet (2) is positioned at the centre of described medicated bag (1), and respectively there are 8 layers of degreasing cotton gauze (3) described tablet (2) both sides.
3. a kind of rinsing the mouth medicated bag for the treatment of buccal cavity fungal infection according to claim 1, is characterized in that, the length of described spun yarn rope (4) is greater than the half of the transverse width of described degreasing cotton gauze (3).
4. a kind of rinsing the mouth medicated bag for the treatment of buccal cavity fungal infection according to claim 1, it is characterized in that, described tablet (2) comprises the raw material of following dosage: the nystatin sheet half of 500,000 units and the Sodium Bicarbonate Tablets half of 0.5g.
5. treat a manufacture method for the rinsing the mouth medicated bag of buccal cavity fungal infection, it is characterized in that, comprise the steps:
(1) medicated bag is prepared: get 1 piece of rectangular degreasing cotton gauze (3), vertical along midline doubling 1 time, launch, by two edge center lines respectively to interior doubling, then laterally along midline doubling, launch, by two edge center lines respectively to interior doubling, put a spun yarn rope (4) in the midline of transverse direction, pass as frenulum, more laterally along midline doubling 1 time, finally vertical along midline doubling 1 time, sew up the both sides of 2 wireless openings with line (5), obtain medicated bag (1), sterilizing;
(2) tablet taking (2), loads in the medicated bag after step (1) sterilizing, by spun yarn rope (4) two ends to drawing, and tightening pocket opening;
(3) with the medicated bag (1) of water-soaked step (2) tightening pocket opening, patient oral cavity is put into, by outside spun yarn rope (4) indwelling oral cavity, rinsing the mouth.
6. a kind of manufacture method for the treatment of the rinsing the mouth medicated bag of buccal cavity fungal infection according to claim 5, it is characterized in that, the length of step (1) described spun yarn rope (4) is greater than the half of described degreasing cotton gauze (3) transverse width.
7. a kind of manufacture method for the treatment of the rinsing the mouth medicated bag of buccal cavity fungal infection according to claim 5, it is characterized in that, step (2) described tablet (2) comprises the raw material of following dosage: the nystatin sheet half of 500,000 units and the Sodium Bicarbonate Tablets half of 0.5g.
8. a kind of manufacture method for the treatment of the rinsing the mouth medicated bag of buccal cavity fungal infection according to claim 5, is characterized in that, the time of step (3) described rinsing the mouth is 10 ~ 30 minutes/time, 3 ~ 5 times/day.
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| CA2658638A1 (en) * | 2008-04-07 | 2009-10-07 | Tsukioka Co., Ltd. | Formulation for oral administration |
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| CN102125501A (en) * | 2010-01-14 | 2011-07-20 | 董黎 | Quick buccal medicine administration method |
| CN102362878A (en) * | 2011-10-25 | 2012-02-29 | 徐柔云 | Sustained-release flaky medicine package for treating gingivitis and toothache caused by gingivitis |
| CN102362933A (en) * | 2011-10-25 | 2012-02-29 | 徐柔云 | Sustained-release tablet-shaped cachets used for treating toothache caused by excessive internal heat |
| CN205031578U (en) * | 2015-10-15 | 2016-02-17 | 桂林医学院附属医院 | Cartridge bag is gargled in containing of treatment oral cavity fungal infection |
-
2015
- 2015-10-15 CN CN201510666341.7A patent/CN105213421A/en active Pending
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1213537A (en) * | 1998-07-26 | 1999-04-14 | 曾德惠 | Novel oral cavity medicine |
| WO2001005352A1 (en) * | 1999-07-19 | 2001-01-25 | Andrew John Ashworth | Apparatus and method for administration of medication |
| CN1964896A (en) * | 2004-04-08 | 2007-05-16 | 马丁·威廉·德雷森 | Chewing bag containing herbal material, is made of non-toxic textile to hold pulp of herbal material |
| CA2658638A1 (en) * | 2008-04-07 | 2009-10-07 | Tsukioka Co., Ltd. | Formulation for oral administration |
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| CN102362933A (en) * | 2011-10-25 | 2012-02-29 | 徐柔云 | Sustained-release tablet-shaped cachets used for treating toothache caused by excessive internal heat |
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Application publication date: 20160106 |