CN102125501A - Quick buccal medicine administration method - Google Patents
Quick buccal medicine administration method Download PDFInfo
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- CN102125501A CN102125501A CN2010100049522A CN201010004952A CN102125501A CN 102125501 A CN102125501 A CN 102125501A CN 2010100049522 A CN2010100049522 A CN 2010100049522A CN 201010004952 A CN201010004952 A CN 201010004952A CN 102125501 A CN102125501 A CN 102125501A
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- medicine
- buccal
- bag
- medicated bag
- absorption
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Abstract
At present, tablets and granules are mainly adopted in sublingual buccal medicine administration for emergent rescue. Buccal medicine administration requires the whole tablet (or granule) to be dissolved before the active ingredients are absorbed effectively, and the speed of buccal medicine administration is thus affected. The invention provides a method for improving the speed of buccal medicine administration by a special buccal medicine administration bag. The medicine bag (2) is made of cotton or other rolling-resistance and water-absorbing fiber products with proper woven mesh size; the size and shape (like a small long strip or a crescent) of the medicine bag are proper for the medicine bag to be placed under the tongue and contain a plurality of tablets; and the tablets (1) are conventional buccal tablets or granules. When the method is used, the tablets (1) in the medicine bag (2) can be extruded into powder by rolling with a tool or biting with teeth and the powder does not scatter. When the medicine is placed under tongue, the absorption speed and effect of the medicine are improved completely due to the high water absorbability of the medicine bag (2), a large absorption surface area and a high medicine dissolution speed. On the basis of the method provided by the invention, absorption efficiency can be further increased by methods such as promoting mucosa absorption, using a shell and using after the medicine dips water.
Description
Affiliated technical field
The present invention relates to the medical medicine field, be specifically a kind of can be with sheet (or granule) the agent medicine medication of containing fast.
Background technology
Patient's disease sublingual administration administration (especially saving oneself before the institute) of bursting is one of rapid emergency treatment medication.Owing to must consider in the pharmaceutical technology to take and store conveniently; usually can a small amount of active drug composition in (mostly being the milligram level) add a large amount of excipient (as starch) extruding (or granule) shape in flakes; said method has made things convenient for the conventional oral administration that gastrointestinal absorbs that passes through; but when first aid needs the quick administration of sublingual administration, then must dissolve whole tablet (or granule) can be with it in a small amount of active drug composition absorb, influence speed of delivery.For improving speed of delivery, clinical normal employing grinds tablet in advance and inserts the sublingual administration method again in the medicine ware, but this method is ground unavoidable remaining more medicated powder on the tablet utensil at stone roller; Medicated powder is all accurately inserted difficulty of Sublingual; Insert the Sublingual again and take certain hour by the grinding of medicine ware, taking-up; Patient is difficult to implement to grind containing of tablet voluntarily and saves oneself under no medical care or other personnel help.In addition, may need several medicines in the first aid, take out one by one by taking dose in the packings such as different medicine bottle medicine boxs respectively and also stop over certain hour, in the burst emergency case of some person in middle and old age's cardiovascular and cerebrovascular vessel, incur loss through delay the most valuable treatment opportunity owing to patient at short notice loses ability to act.If can provide a kind of the first aid medicine is left concentratedly in advance, can grind and conveniently insert the Sublingual fast when needing and have the containing method of higher absorption efficiency will improve first aid speed and effect.
Summary of the invention
(especially saving oneself before the institute) improves containing of tablet speed, effect, convenient feasible quick medication when the purpose of this invention is to provide a kind of first aid.
Realize that technical scheme of the present invention is: design the special medicated bag of containing that a size and shape can conveniently be inserted the human body Sublingual, can put into the fibre of several tablets in advance.This medicated bag can using appliance grind or tooth not damaged when biting inner tablet into pieces, keep medicated powder not leak; Water absorption and to knit the hole trafficability characteristic better can receive moisture content that inner active drug meal component is absorbed by the hypoglossis mucous membrane blood vessel fast by knitting the hole infiltration when containing into the Sublingual; It is direct or accurately insert the Sublingual with tongue that medicated bag is convenient to the hand-held oral cavity of putting into; Simultaneously, the more single tablet surface area multiplication of medicated bag whole surface area increases medicine at the hypoglossis mucous membrane absorption area; In addition, as bite into pieces after the medicated bag that includes tablet may being got wet containing or earlier with apparatus with the inner tablet of medicated bag grind into powder again integral body get wet directly that containing can further improve containing infiltration rate and effect.This use can also expand on the special medicated bag method basis derive a kind of special specialize in first aid fast containing with new pharmaceutical dosage form, promptly do not use excipient and will use the former medicated powder of first aid always and directly insert in the fibre medicated bag, the outer parcel of medicated bag is easily pinched, is bitten into pieces or the rapidly-soluble can of containing (as sugar-coat).But this dosage form fiber interliner shell figuration becomes the class capsule shape, inner airtightly be beneficial to inner former medicine composition and guarantee the quality, and pinches during use, bites into pieces or contain outside the pale of civilization shell to place the Sublingual to get final product.Quicken Transdermal absorption as the ancillary drug that on medicated bag, immerses a small amount of short mucosa absorption, also can further improve absorption efficiency.
Beneficial effect of the present invention is with a speed and an effect simple, reliable, the easily raising sublingual administration administration of row, safe method maximal efficiency, improves the burst disease patient and realizes the probability of saving oneself.
Description of drawings
Below in conjunction with accompanying drawing the present invention is further narrated:
Fig. 1 uses the tablet sketch map for now sucking
1, tablet 2, ingredient
Fig. 2 is a sketch map one of the present invention
1, tablet 2, special medicated bag
Fig. 3 is a sketch map two of the present invention
1, medicated powder 2, special medicated bag 3, shell
Specific embodiments
Fig. 1 uses the tablet sketch map for now sucking: add the ingredient (2) that contains a small amount of performance therapeutical effect in the tablet (1) of a large amount of excipient.If must the long period dissolve whole tablet when being used to containing administration, ingredient could all absorb.
Fig. 2 is a structure chart one of the present invention: constitute by sucking with tablet (1) and special medicated bag (2).Medicated bag (2) is made of the suitable fibre of cotton or other rolling resistance, water absorption and slot size, and size and shape are suitable for inserting the Sublingual and put into several tablets (as little rectangular, ellipse or selenodont).Tablet (1) then can be sucked medication (or granule) for existing.Roll with utensil during use or the interior tablet of medicated bag (2) (1) can be squeezed into powdery and not be scattered with dental articulation, medicated bag when inserting the Sublingual (2) and powdery medicine have than single tablet (1) better water absorption, bigger sorbent surface is long-pending and dissolution velocity faster, thereby promote drug absorption speed and effect comprehensively.Can insert used several types of drugs of first aid and medicated bag in advance and extract than the more easy-to-use finger of tablet, will be originally must be respectively from medicine bottle number action such as get it filled be reduced to disposable finishing, and containing after can getting wet smoothly, delivery rate and effect further improve.Quicken Transdermal absorption as go up the ancillary drug that immerses a small amount of short mucosa absorption at medicated bag (2), also can further improve absorption efficiency.
Fig. 3 is a sketch map two of the present invention: be made of medicated powder (1), fibre medicated bag (2) and shell (3).Medicated powder (1) can be former medicine composition, and anti-medicated powder directly leaks outside fibre medicated bag (2) except that keeping, suction, medicine trafficability characteristic and to increase effect such as absorption area to shell (3) liner reinforcement effect in addition.To the suitable power extruding of shell (3) or containing rear casing (3) breaks or fast instantizing loses seal, place Sublingual medicated powder (1) to pass through fibre medicated bag (2) rapid osmotic during use, through mucous membrane can absorb.
Claims (3)
1. containing medication (Fig. 2 shows) fast, form by sucking with special medicated bag (2) and tablet that first aid is used or drug particles (1), it is characterized in that: medicated bag (2) size shape is made into not only suitable several common tablets but also the rectangular or crescent shape suitable with human body Sublingual spatial form of inserting; Material selection rolling resistance or interlock are not broken, and water absorption is cotton or other fibre preferably; The weaving compactness forms knits hole size and is controlled at and can prevents that powdery medicated powder from leaking and can guarantee that medicated powder dissolves the back rapid osmotic and goes out.
2. a kind of medication of containing fast according to claim 1 (Fig. 3 shows) is characterized in that: the outer sealing shell (3) that increases on special medicated bag (2) basis, and this shell (3) easily breaks when less external force or containing or dissolves rapidly; Former medicine powder (1) is directly inserted in the medicated bag (2), and shell (3) forms airtight inner space can play anti-leak and the effect of guaranteeing the quality to former medicine powder (1); Squeeze broken or dissolve shell (3) the former medicine powder in back (1) and can ooze out fast from special medicated bag (2).
3. a kind of medication of containing fast according to claim 1 (Fig. 2,3 shows) is characterized in that: the ancillary drug that can add or immerse a small amount of short mucosa absorption on medicated bag (2) quickens Transdermal absorption, further improves absorption efficiency.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010100049522A CN102125501A (en) | 2010-01-14 | 2010-01-14 | Quick buccal medicine administration method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010100049522A CN102125501A (en) | 2010-01-14 | 2010-01-14 | Quick buccal medicine administration method |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102125501A true CN102125501A (en) | 2011-07-20 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2010100049522A Pending CN102125501A (en) | 2010-01-14 | 2010-01-14 | Quick buccal medicine administration method |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102125501A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105213421A (en) * | 2015-10-15 | 2016-01-06 | 桂林医学院附属医院 | A kind of rinsing the mouth medicated bag for the treatment of buccal cavity fungal infection and preparation method thereof |
-
2010
- 2010-01-14 CN CN2010100049522A patent/CN102125501A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105213421A (en) * | 2015-10-15 | 2016-01-06 | 桂林医学院附属医院 | A kind of rinsing the mouth medicated bag for the treatment of buccal cavity fungal infection and preparation method thereof |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| ASS | Succession or assignment of patent right |
Owner name: LANZHOU WENHE MEDICAL EQUIPMENT RESEARCH + DEVELOP Free format text: FORMER OWNER: DONG LI Effective date: 20110920 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20110920 Address after: 730050, No. 1, South Street, LAN Gong, Qilihe District, Gansu, Lanzhou Applicant after: Lanzhou Wenhe Medical Device Research Development Co., Ltd. Address before: 730050 Gansu province Qilihe District, Lanzhou City, 1 South Street, Lanzhou medical equipment research and Development Co., Ltd. Applicant before: Dong Li |
|
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20110720 |