CN105194382A - Preparation for treating urethritis and preparation method thereof - Google Patents
Preparation for treating urethritis and preparation method thereof Download PDFInfo
- Publication number
- CN105194382A CN105194382A CN201510653410.0A CN201510653410A CN105194382A CN 105194382 A CN105194382 A CN 105194382A CN 201510653410 A CN201510653410 A CN 201510653410A CN 105194382 A CN105194382 A CN 105194382A
- Authority
- CN
- China
- Prior art keywords
- parts
- herba
- radix
- minute
- concentrated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Abstract
The invention discloses a preparation for treating acute urethritis. The preparation is prepared from the following main raw materials in parts by weight: 6-10 parts of caulis akebiae, 9-14 parts of miquel maqzus, 10-15 parts of nauclea officinalis, 8-16 parts of glossogyne tenuifolia, 9-15 parts of cherry leaves, 11-16 parts of lotus petiole petiolus, 7-14 parts of fructus kochiae, 9-13 parts of helleborus thibetanus, 8-14 parts of colysis digitata, 7-13 parts of obscured homalomena rhizome, 11-17 parts of lophatherum gracile, 9-16 parts of Japanese nanocnide herb, 7-15 parts of fortune microsorium herb with root, 6-14 parts of pogostemon auricularius and 8-15 parts of bambooleaf pricklyash root. The preparation is prepared from compatible medicinal materials, accords with traditional Chinese medicine and modern medicine theories, has the effects of clearing heat, removing toxicity, nourishing yin, reducing internal fire, diminishing swelling, relieving pain, inducing diuresisand dredging stranguria, has the advantages of remarkable curative effect, quick response and relapse prevention after healing when being used for treating urethritis, and is safe and reliable.
Description
Technical field
The invention belongs to traditional Chinese medicine field, especially relate to a kind of preparation and the method for making of curing acute urethritis.
Background technology
Acute urethritis can be divided into bacterial urethritis, gonococcal urethritis and nongonococcal urethritis.The overweight conditions of acute urethritis in Aeg has more urethral secretions, and prelude is mucus, graduates into purulence, and in aeg, urethral secretions is unique.No matter men and women, when urinating, urethra all has burning pain, frequent micturition and urgent micturition, and severe one urethrospasm can occur.Uroscopy has pus cell and erythrocyte.Slow urethritis urethral secretions is reduced gradually, or when only first time urinates in the morning, can have a small amount of serosity secretions by apparent urethral orifice.Irritation of urinating understands work unlike acute stage, and some patients can be asymptomatic.Urethritis can cause cystitis or prostatitis to bladder or prostate by direct extension.If acute urethritis is mishandling, can the other abscess of concurrent urethra, abscess can wear out skin of penis becomes urethral fistula.In urinary tract inflammation agglutination, it is narrow that fibrosis then can cause urethra.At present, nongonococcal urethritis is higher than gonococcal urethritis sickness rate, walks caused by unclean property conduct pollution primarily of chlamydia trachomatis amiable urine mycoplasma.
A kind of genital infection disease that acute urethritis right and wrong are usually shown in, because pathogenic bacterium difference is also divided into the urethritis of many types.Different types of urethritis has different pathogenic factors.1. bacterial urethritis is caused by various bacterial invasion urethra (such as: escherichia coli etc.).2. gonococcal urethritis is via antihygienic sexual life, is caused by Neisser gonorrhea diplococcus.Main manifestations is: after infecing gonococcal urethritis, usually have 2 ~ 5 days dodge the phase, when just having started to fall ill, symptom is urethral orifice redness, itches, there is slight twinge, and then just occur urethral orifice purulent secretion, and gradually aggravate, patient's urethral orifice often secreted thing seals, if this time does not take special treatment, can be changed into chronic gonococcal urethritis, a part of patient can secondary prostatitis, seminal vesiculitis, epididymitis etc.3. urethritis kind also has nongonococcal urethritis.
The Measures compare of existing Chinese traditional treatment acute urethritis is many, publication number CN104771662A(application number 201510110765.5) patent discloses a kind of Chinese medicine composition for the treatment of urethritis, the weight portion of its constitutive material is: Radix Rehmanniae 5-10, Herba Dianthi 4-6, Cortex Lycii 6-8, Flos Lonicerae 15-20, Caulis Akebiae 4-5, Rhizoma Smilacis Glabrae 7-9, Fructus Toosendan 4-5, Radix Ephedrae 2-4, Herba Ixeritis polycephalae 1-3, Rhizoma Anemarrhenae 6-8, Radix Platycodonis 5-8, Herba Sarcandrae 4-5, Cortex Phellodendri 8-10, Rhizoma Polygoni Cuspidati 2-4, Herba Violae 6-8, Flos Lonicerae 20-25, Cortex Moutan 8-10, Scorpio 6-8, Radix Scutellariae 3-5, Fructus Gardeniae 2-4, Radix Seu Caulis Mucunae Sempervirentis 1-3, Radix Crataevae Unilocularis 2-4.Publication number CN104147431A(application number 201410442525.0) patent discloses a kind of medicament for the treatment of chronic urethritis and preparation method thereof, crude drug comprises major ingredient and adjuvant, described major ingredient by weight component meter is made up of following crude drug: cup chrysanthemum 80-140 part, Herba Christiae Obcordatae 55-85 part, Caulis Achnatheri Splendentis 20-40 part, Folium Salicis Babylonicae 36-56 part, red autumnal leaves Radix clematidis floridae 27-45 part, soil Radix Glycyrrhizae 34-50 part, great Ye Rohdea japonica Roth 28-42 part, Semen Benincasae 60-84 part, Folium Vaccinii vitis-idaeae 35-65 part, Poria 60-80 part, Rhizoma Alismatis 26-40 part, Rhizoma Atractylodis Macrocephalae 50-75 part, Herba Lophatheri 35-60 part, fresh Rhizoma Phragmitis 76-100 part, Semen Abutili 30-50 part, described adjuvant by weight component meter is made up of following crude drug: Radix Et Caulis Acanthopanacis Senticosi 26-48 part, Habenria petelotii Gagnep. 25-65 part, Pericarpium Vignae sinensis 12-60 part, Flos Rosae Chinensis 10-30 part, Radix Buddlejae Butterflybush 15-35 part.Publication number CN103479816A(application number 201310464774.5) patent discloses a kind of Chinese medicine for the treatment of nongonococcal urethritis, it is made up of following raw material medicaments: Drymoglossum Herba Drymoglossi 30-50 part, Cortex Phellodendri 30-50 part, Herba Andrographis 30-50 part, Fructus Schisandrae Chinensis 20-30 part, Rhizoma Alismatis 20-30 part, Rhizoma Menispermi 20-30 part, Herba Dianthi 20-30 part, Fructus Gardeniae 10-20 part, Radix Rehmanniae 10-20 part, Rhizoma Atractylodis Macrocephalae 10-20 part, Radix Glycyrrhizae 10-20 part.
Current treatment acute urethritis many employings western medical treatment, normal employing antibiotic and chemicals use in conjunction, although curative effect is better, abuse of antibiotics is induced renal damage not only, also easily causes dysbacteriosis, and acute urethritis repeatedly.And life-time service easily produces drug resistance, do not have good effect to acute urethritis, easily recur, outcome is poor.Though the Chinese medicine of more existing treatment acute urethritiss at present, most uncertain therapeutic efficacy is cut.
Summary of the invention
For the deficiencies in the prior art, an object of the present invention is to provide a kind of preparation of curing acute urethritis, selected medical material compatibility is suitable, meet Chinese medicine and pharmacy and modern medicine theory, there is heat-clearing and toxic substances removing, effect of nourishing YIN to lower pathogenic fire, reducing swelling and alleviating pain, relieving stranguria by diuresis, treatment urethritis is evident in efficacy, instant effect, cures and does not recur, safe and reliable.Another object of the present invention is to provide above-mentioned a kind of preparation method curing the preparation of acute urethritis.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
Cure a preparation for acute urethritis, take off the primary raw material stating weight proportion and be prepared from: Caulis Akebiae 6-10 part; Herba mazi japonici 9-14 part; Lignum et Radix Naucleae 10-15 part; Herba bidentis parviflorae 8-16 part; Folium Pruni pseudocerasi 9-15 part; Petiolus nelumbinis 11-16 part; Fructus Kochiae 7-14 part; Radix Chimonanthi praecocis 9-13 part; Cliff lotus 8-14 part; Rhizoma Homalomenae 7-13 part; Herba Lophatheri 11-17 part; Herba Nanocnides Japonicae 9-16 part; Microsorium fortunei (Moore) ching 7-15 part; Water hair penetrates 6-14 part; Radix Zanthoxyli Planispini 8-15 part.
Cure a preparation for acute urethritis, preferred scheme is, takes off the primary raw material stating weight proportion and is prepared from: Caulis Akebiae 7-9 part; Herba mazi japonici 11-13 part; Lignum et Radix Naucleae 12-14 part; Herba bidentis parviflorae 11-13 part; Folium Pruni pseudocerasi 11-13 part; Petiolus nelumbinis 13-15 part; Fructus Kochiae 10-12 part; Radix Chimonanthi praecocis 10-12 part; Cliff lotus 10-12 part; Rhizoma Homalomenae 9-11 part; Herba Lophatheri 13-15 part; Herba Nanocnides Japonicae 12-14 part; Microsorium fortunei (Moore) ching 10-12 part; Water hair penetrates 9-11 part; Radix Zanthoxyli Planispini 11-13 part.
Cure a preparation for acute urethritis, the scheme be more preferably is, takes off the primary raw material stating weight proportion and is prepared from: Caulis Akebiae 8 parts; Herba mazi japonici 12 parts; Lignum et Radix Naucleae 13 parts; Herba bidentis parviflorae 12 parts; Folium Pruni pseudocerasi 12 parts; Petiolus nelumbinis 14 parts; The Fructus Kochiae 11 parts; Radix Chimonanthi praecocis 11 parts; 11 parts, cliff lotus; Rhizoma Homalomenae 10 parts; Herba Lophatheri 14 parts; Herba Nanocnides Japonicae 13 parts; Microsorium fortunei (Moore) ching 11 parts; Water hair penetrates 10 parts; Radix Zanthoxyli Planispini 12 parts.
Present invention also offers the preparation method above-mentioned a kind of preparation of curing acute urethritis being made pharmaceutically acceptable decoction, granule, concentrated pill, Tablet and Capsula.
Described a kind of preparation method curing the preparation decoction of acute urethritis, step is as follows:
(1) be placed in pot by Caulis Akebiae and the Fructus Kochiae, slow fire fries 20-30 minute, mechanical activation comminution, excessively 130-150 mesh sieve (preferred 136-144 mesh sieve excessively, was more preferably 140 mesh sieves);
(2) Folium Pruni pseudocerasi, Petiolus nelumbinis and Herba Lophatheri are cleaned, be placed in container, add water, moistening 3-5 hour, is placed in juicer, and strand juice, filters;
(3) Rhizoma Homalomenae, Microsorium fortunei (Moore) ching and Radix Zanthoxyli Planispini are cut into slices, be placed in glass container, add white vinegar, moistening 4-6 hour, take out, dry;
(4) Herba mazi japonici, Lignum et Radix Naucleae, Herba bidentis parviflorae, Radix Chimonanthi praecocis, cliff lotus, Herba Nanocnides Japonicae and water hair are penetrated clean, be placed in container, add water and cover powder 2-3cm, soak 40-60 minute, take out, be placed in multi-function extractor, add step (3) gains, extracting in water twice, each extraction 40-50 minute (preferably each extraction 43-47 minute, be more preferably each extraction 45 minutes), merge extractive liquid, concentrated juice relative density is 1.00-1.10(25 DEG C) concentrated solution;
(5) step (1) gained fine powder is joined in step (4) gained concentrated solution, mixing, filter, add step (2) gained medicinal liquid, stir 2-3 minute, filter, sterile packaged.
According to preparation method recited above, the consumption of the preferred white vinegar of step (3) is 30%40% of Rhizoma Homalomenae, Microsorium fortunei (Moore) ching and Radix Zanthoxyli Planispini gross mass, and the consumption being more preferably white vinegar is 35% of Rhizoma Homalomenae, Microsorium fortunei (Moore) ching and Radix Zanthoxyli Planispini gross mass.
Instructions of taking: each 100-150ml, every day 2 times, 2 days courses for the treatment of.
Described a kind of preparation method curing the preparation granules agent of acute urethritis, step is as follows:
(1) be placed in pot by Caulis Akebiae and the Fructus Kochiae, slow fire fries 20-30 minute, mechanical activation comminution, excessively 130-150 mesh sieve (preferred 136-144 mesh sieve excessively, was more preferably 140 mesh sieves);
(2) Folium Pruni pseudocerasi, Petiolus nelumbinis and Herba Lophatheri are cleaned, be placed in container, add water, moistening 3-5 hour, is placed in juicer, and strand juice, filters;
(3) Rhizoma Homalomenae, Microsorium fortunei (Moore) ching and Radix Zanthoxyli Planispini are cut into slices, be placed in glass container, (consumption of preferred white vinegar is 30%40% of Rhizoma Homalomenae, Microsorium fortunei (Moore) ching and Radix Zanthoxyli Planispini gross mass to add white vinegar, the consumption being more preferably white vinegar is 35% of Rhizoma Homalomenae, Microsorium fortunei (Moore) ching and Radix Zanthoxyli Planispini gross mass), moistening 4-6 hour, take out, dry;
(4) Herba mazi japonici, Lignum et Radix Naucleae, Herba bidentis parviflorae, Radix Chimonanthi praecocis, cliff lotus, Herba Nanocnides Japonicae and water hair are penetrated clean, be placed in container, add water and cover powder 2-3cm, soak 40-60 minute, take out, be placed in multi-function extractor, add step (3) gains, extracting in water twice, each extraction 40-50 minute (preferably each extraction 43-47 minute, be more preferably each extraction 45 minutes), merge extractive liquid, concentrated juice relative density is 1.00-1.10(25 DEG C) concentrated solution;
(5) step (1) gained fine powder is joined in step (4) gained concentrated solution, mixing, filter, add step (2) gained medicinal liquid, stir 2-3 minute, filter, be concentrated into relative density 1.10-1.20(25 DEG C) thick paste, make uniform fine particle, be aided with pharmaceutically acceptable carrier package, the quality of every parcel is 6g.
According to preparation method recited above, step (5) is preferably concentrated into the thick paste of relative density 1.13-1.17, is more preferably the thick paste being concentrated into relative density 1.15.
Instructions of taking: each 1 bag, takes after melting, every day 2 times, 2 days courses for the treatment of by warm water.
Described a kind of preparation method curing the preparation concentrated pill of acute urethritis, step is as follows:
(1) be placed in pot by Caulis Akebiae and the Fructus Kochiae, slow fire fries 20-30 minute, mechanical activation comminution, excessively 130-150 mesh sieve (preferred 136-144 mesh sieve excessively, was more preferably 140 mesh sieves);
(2) Folium Pruni pseudocerasi, Petiolus nelumbinis and Herba Lophatheri are cleaned, be placed in container, add water, moistening 3-5 hour, is placed in juicer, and strand juice, filters;
(3) Rhizoma Homalomenae, Microsorium fortunei (Moore) ching and Radix Zanthoxyli Planispini are cut into slices, be placed in glass container, (consumption of preferred white vinegar is 30%40% of Rhizoma Homalomenae, Microsorium fortunei (Moore) ching and Radix Zanthoxyli Planispini gross mass to add white vinegar, the consumption being more preferably white vinegar is 35% of Rhizoma Homalomenae, Microsorium fortunei (Moore) ching and Radix Zanthoxyli Planispini gross mass), moistening 4-6 hour, take out, dry;
(4) Herba mazi japonici, Lignum et Radix Naucleae, Herba bidentis parviflorae, Radix Chimonanthi praecocis, cliff lotus, Herba Nanocnides Japonicae and water hair are penetrated clean, be placed in container, add water and cover powder 2-3cm, soak 40-60 minute, take out, be placed in multi-function extractor, add step (3) gains, extracting in water twice, each extraction 40-50 minute (preferably each extraction 43-47 minute, be more preferably each extraction 45 minutes), merge extractive liquid, concentrated juice relative density is 1.00-1.10(25 DEG C) concentrated solution;
(5) step (1) gained fine powder is joined in step (4) gained concentrated solution, mixing, filter, add step (2) gained medicinal liquid, stir 2-3 minute, filter, be concentrated into relative density 1.10-1.20(25 DEG C) thick paste (be preferably concentrated into the thick paste of relative density 1.13-1.17, be more preferably the thick paste being concentrated into relative density 1.15), (preferred diameter is 3-5mm to make concentrated pill by standard pharmaceutically, being more preferably diameter is 4mm), sterile packaged.
Using method: each 6-10 ball, with warm water delivery service, every day 2 times, 2 days courses for the treatment of.
Described a kind of preparation method curing the formulation tablet of acute urethritis, step is as follows:
(1) be placed in pot by Caulis Akebiae and the Fructus Kochiae, slow fire fries 20-30 minute, mechanical activation comminution, excessively 130-150 mesh sieve (preferred 136-144 mesh sieve excessively, was more preferably 140 mesh sieves);
(2) Folium Pruni pseudocerasi, Petiolus nelumbinis and Herba Lophatheri are cleaned, be placed in container, add water, moistening 3-5 hour, is placed in juicer, and strand juice, filters;
(3) Rhizoma Homalomenae, Microsorium fortunei (Moore) ching and Radix Zanthoxyli Planispini are cut into slices, be placed in glass container, (consumption of preferred white vinegar is 30%40% of Rhizoma Homalomenae, Microsorium fortunei (Moore) ching and Radix Zanthoxyli Planispini gross mass to add white vinegar, the consumption being more preferably white vinegar is 35% of Rhizoma Homalomenae, Microsorium fortunei (Moore) ching and Radix Zanthoxyli Planispini gross mass), moistening 4-6 hour, take out, dry;
(4) Herba mazi japonici, Lignum et Radix Naucleae, Herba bidentis parviflorae, Radix Chimonanthi praecocis, cliff lotus, Herba Nanocnides Japonicae and water hair are penetrated clean, be placed in container, add water and cover powder 2-3cm, soak 40-60 minute, take out, be placed in multi-function extractor, add step (3) gains, extracting in water twice, each extraction 40-50 minute (preferably each extraction 43-47 minute, be more preferably each extraction 45 minutes), merge extractive liquid, concentrated juice relative density is 1.00-1.10(25 DEG C) concentrated solution;
(5) step (1) gained fine powder is joined in step (4) gained concentrated solution, mixing, filter, add step (2) gained medicinal liquid, stir 2-3 minute, filter, be concentrated into relative density 1.10-1.20(25 DEG C) thick paste (be preferably concentrated into the thick paste of relative density 1.13-1.17, be more preferably the thick paste being concentrated into relative density 1.15), become tablet by metric system pharmaceutically, sugar coating.
Instructions of taking: each 2-3 sheet, every day 2 times, 2 days courses for the treatment of.
Described a kind of preparation method curing the preparation capsule of acute urethritis, step is as follows:
(1) be placed in pot by Caulis Akebiae and the Fructus Kochiae, slow fire fries 20-30 minute, mechanical activation comminution, excessively 130-150 mesh sieve (preferred 136-144 mesh sieve excessively, was more preferably 140 mesh sieves);
(2) Folium Pruni pseudocerasi, Petiolus nelumbinis and Herba Lophatheri are cleaned, be placed in container, add water, moistening 3-5 hour, is placed in juicer, and strand juice, filters;
(3) Rhizoma Homalomenae, Microsorium fortunei (Moore) ching and Radix Zanthoxyli Planispini are cut into slices, be placed in glass container, (consumption of preferred white vinegar is 30%40% of Rhizoma Homalomenae, Microsorium fortunei (Moore) ching and Radix Zanthoxyli Planispini gross mass to add white vinegar, the consumption being more preferably white vinegar is 35% of Rhizoma Homalomenae, Microsorium fortunei (Moore) ching and Radix Zanthoxyli Planispini gross mass), moistening 4-6 hour, take out, dry;
(4) Herba mazi japonici, Lignum et Radix Naucleae, Herba bidentis parviflorae, Radix Chimonanthi praecocis, cliff lotus, Herba Nanocnides Japonicae and water hair are penetrated clean, be placed in container, add water and cover powder 2-3cm, soak 40-60 minute, take out, be placed in multi-function extractor, add step (3) gains, extracting in water twice, each extraction 40-50 minute (preferably each extraction 43-47 minute, be more preferably each extraction 45 minutes), merge extractive liquid, concentrated juice relative density is 1.00-1.10(25 DEG C) concentrated solution;
(5) step (1) gained fine powder is joined in step (4) gained concentrated solution, mixing, filters, adds step (2) gained medicinal liquid, stir 2-3 minute, filter, be concentrated into relative density 1.20-1.30(25 DEG C) thick paste (be preferably concentrated into the thick paste of relative density 1.23-1.27, be more preferably the thick paste being concentrated into relative density 1.25), dry, pulverize, make capsule (preferred 0.4-0.6g/ grain, is more preferably 0.5g/ grain).
Instructions of taking: each 2-3 grain, every day 2 times, 2 days courses for the treatment of.
The pharmacological effect of each crude drug is respectively:
Caulis Akebiae: bitter in the mouth, cold nature.GUIXIN, small intestinal, urinary bladder channel.For the dry rattan of plants of Lardizabalaceae Caulis Akebiae, threeleaf akebia or Caulis Akebiae.There is clearing away heart-fire, diuresis, the effect of stimulating milk secretion of stimulating the menstrual flow.For irritable feverish sensation in the chest, larynx disease pharyngalgia, dark coloured urine, five types of stranguria, edema, whole body spasm and pain, amenorrhea breast is few.
Herba mazi japonici: bitter in the mouth, micro-sweet, cool in nature.For the herb of goatweed Mazus japonicus.Have heat-clearing and toxic substances removing, dampness removing is treating stranguria, effect of spleen invigorating removing food stagnancy.For pyretic toxicity carbuncle, impetigo, furuncle, burn and scald, urinary tract infection, ascites, icterohepatitis, aquation is bad, infantile malnutrition.
Lignum et Radix Naucleae: bitter in the mouth, cold in nature.Return lung, large intestine, gallbladder, urinary bladder channel.For branch, the bark of Maguireothamnus speciosus Lignum et Radix Naucleae.Containing alkaloids and glycoalkaloids.There is heat-clearing and toxic substances removing, effect of reducing swelling and alleviating pain.For cold, fever, bronchitis, pneumonia, acute tonsillitis, pharyngolaryngitis, mastitis, enteritis, bacillary dysentery, urinary tract infection, cholecystitis, ulcer of the lower limb, tinea pedis infects, furuncle and phyma pus infections, dermatitis and eczema.
Herba bidentis parviflorae: mildly bitter flavor, micro-pungent.Cool in nature.For the herb of feverfew Herba bidentis parviflorae.Containing luteolin-7-O-β-D-glucopyanoside, luteolin.There is clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling, effect of promoting blood circulation and hemostasis.For dysentery, edema of having loose bowels, cough, asthma, tonsillitis, hemoptysis, hematuria, carbuncle furuncle and phyma poison, herpes zoster, treating swelling and pain by traumatic injury, traumatic hemorrhage.
Folium Pruni pseudocerasi: sweet in the mouth, hardship, warm in nature.Return liver, spleen, lung meridian.For the leaf of rosaceous plant Fructus Pruni pseudocerasi.Have warming middle-JIAO and strengthening the spleen, cough-relieving is stopped blooding, effect of removing toxic substances parasite killing.For cold syndrome of the stomach food stagnation, diarrhoea, cough, spits blood, and skin infection swells carbuncle, snake bite and insect sting, trichomonas vaginitis.
Petiolus nelumbinis: bitter in the mouth, property is put down.Return spleen, urinary bladder channel.For petiole or the anthocaulus of nymphaeaceae plant lotus.Containing speckle Asia papaverine, the alkaloids such as miltanthin, flavonoid glycoside, agedoite, resin and tannin.There is expelling summer-heat heat clearing away, effect of regulating QI to expel dampness.Do not relax for heat-damp in summer is uncomfortable in chest, have loose bowels, dysentery, gonorrhea, leukorrhagia.
The Fructus Kochiae: acrid in the mouth, hardship, cold in nature.Return kidney, urinary bladder channel.For the dry mature fruit of Li Ke plant Fructus Kochiae.There is clearing away heat-damp and promoting diuresis, effect of dispelling wind for relieving itching.For difficulty and pain in micturition, pudendal pruritus leukorrhagia, rubella, eczema, skin pruritus.
Radix Chimonanthi praecocis: bitter in the mouth, cool in nature.For the root of cohosh Radix Chimonanthi praecocis.Containing cardiotonic glycoside hellebrigenin glucorhamnoside., bufotalidin, Helleborus poison glycoside, helleborin.There is heat-clearing and toxic substances removing, promoting blood circulation to remove blood stasis, effect of reducing swelling and alleviating pain.For cystitis, urethritis, furuncle toxic swelling, traumatic injury, impairment caused by overstrain.
Cliff lotus: mildly bitter flavor, cool in nature.For the leaf of Plants of Polypodiaceae Colysis digitata (Bak) Ching..There is promoting blood circulation to remove blood stasis, removing toxic substances pain relieving, effect of inducing diuresis for treating stranguria syndrome.For traumatic injury, rheumatalgia, venom, pyretic stranguria, stranguria caused by urinary stone.
Rhizoma Homalomenae: bitter in the mouth, pungent, warm in nature.Return liver, kidney channel.For the dry rhizome of Rhizoma Arisaematis kind of plant Rhizoma Homalomenae.There is wind-damp dispelling, effect of muscle reinforcing and bone strengthening.For anemofrigid-damp arthralgia, chills and pain of the waist and kness, lower limb contracture is numb.
Herba Lophatheri: sweet in the mouth, light, cold in nature.GUIXIN, stomach, small intestine meridian.For the dry stem and leaf of grass Herba Lophatheri.There is clearing heat and relieving fidgetness, effect of diuresis.For calentura excessive thirst, hot urination drenches pain, aphtha of the mouth and tongue.
Herba Nanocnides Japonicae: lightly seasoned, cool in nature.For the herb of contrayerva flower point grass.There is heat-clearing and toxic substances removing, cough-relieving, effect of hemostasis.For jaundice, pulmonary tuberculosis hemoptysis, hectic fever, hemorrhoid, miliaria.
Microsorium fortunei (Moore) ching: bitter in the mouth, cold in nature.Return liver, spleen, the heart, lung meridian.For the rhizome of Tie Jiao swallow section plant Asplenium Griffthianum Hook..There is heat clearing away, removing toxic substances, effect of dampness removing.For jaundice, stranguria with turbid discharge, high heat, burn and scald.
Water hair is penetrated: mildly bitter flavor, pungent, cool in nature.For the herb of labiate water Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis).Containing Auricled Hedyotis Herb acid, 7-hydroxyl Cleistanthus sumafranus (Miq) Muell-Arg-C. Saichikii Merr wood-13,15-diene-18-hydroxy acids, 7-acetoxyl group Cleistanthus sumafranus (Miq) Muell-Arg-C. Saichikii Merr wood-13,15-diene-18-hydroxy acids.Have loose wind heat clearing away, damp eliminating is detoxified, effect of reducing swelling and alleviating pain.For cold, fever, infantile convulsion, rheumatalgia, ileotyphus, hernia, skin ulcer is swollen wet rotten, eczema, infantile carbuncle, venom.
Radix Zanthoxyli Planispini: acrid in the mouth, hardship, warm in nature.Return lung meridian.For root bark or the root of rutaceae Fructus Zanthoxyli Plansipini.Containing .gamma.-fagarine, Flos Magnoliae Liliflorae subtracts, xanthoplanine, dictamine .beta.-fagarine, magnoflorine, Radix Zanthoxyli Bungeani alkali.Have expelling wind and cold, warming middle-JIAO is regulated the flow of vital energy, effect of promoting blood circulation and stopping pain.For rheumatic arthralgia, stomachache with cool feeling, has loose bowels, dysentery, headache due to common cold, and toothache, traumatic injury, dysmenorrhea, knife injury is hemorrhage, stubborn dermatitis, venom.
Technical advantage of the present invention is mainly reflected in:
1, selected by invention formulation preparation, medical material compatibility is suitable, meets Chinese medicine and pharmacy and modern medicine theory, has heat-clearing and toxic substances removing, effect of nourishing YIN to lower pathogenic fire, reducing swelling and alleviating pain, relieving stranguria by diuresis, treatment acute urethritis is evident in efficacy, instant effect, cure and do not recur, safe and reliable.
2, invention formulation is based on the principle for the treatment of acute urethritis, effectively improves autoimmunity, plays the object for the treatment of, instant effect, cure rate are high, the treatment phase is short, has no side effect, can reach the object for the treatment of both the principal and secondary aspects of a disease.
3, this pharmaceutical preparation selected materials great majority are Chinese medicine material, and medical material is easy to get, and cost is low, safe and reliable, wide popularization and application on clinic.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
embodiment 1cure a preparation for acute urethritis, take off and state primary raw material and be prepared from (getting 70g for every part): Caulis Akebiae 6 parts; Herba mazi japonici 9 parts; Lignum et Radix Naucleae 10 parts; Herba bidentis parviflorae 8 parts; Folium Pruni pseudocerasi 9 parts; Petiolus nelumbinis 11 parts; The Fructus Kochiae 7 parts; Radix Chimonanthi praecocis 9 parts; 8 parts, cliff lotus; Rhizoma Homalomenae 7 parts; Herba Lophatheri 11 parts; Herba Nanocnides Japonicae 9 parts; Microsorium fortunei (Moore) ching 7 parts; Water hair penetrates 6 parts; Radix Zanthoxyli Planispini 8 parts.
Above-mentioned a kind of preparation method curing the preparation decoction of acute urethritis, step is as follows:
(1) be placed in pot by Caulis Akebiae and the Fructus Kochiae, slow fire fries 25 minutes, mechanical activation comminution, crosses 140 mesh sieves;
(2) Folium Pruni pseudocerasi, Petiolus nelumbinis and Herba Lophatheri are cleaned, be placed in container, add water, moistening 4 hours, is placed in juicer, and strand juice, filters;
(3) Rhizoma Homalomenae, Microsorium fortunei (Moore) ching and Radix Zanthoxyli Planispini are cut into slices, be placed in glass container, add white vinegar (consumption is 35% of Rhizoma Homalomenae, Microsorium fortunei (Moore) ching and Radix Zanthoxyli Planispini gross mass), moistening 5 hours, take out, dry;
(4) Herba mazi japonici, Lignum et Radix Naucleae, Herba bidentis parviflorae, Radix Chimonanthi praecocis, cliff lotus, Herba Nanocnides Japonicae and water hair are penetrated clean, be placed in container, add water and cover powder 3cm, soak 50 minutes, take out, be placed in multi-function extractor, add step (3) gains, extracting in water twice, each extraction 45 minutes, merge extractive liquid, concentrated juice relative density is 1.05(25 DEG C) concentrated solution;
(5) step (1) gained fine powder is joined in step (4) gained concentrated solution, mixing, filter, add step (2) gained medicinal liquid, stir 3 minutes, filter, sterile packaged.
Instructions of taking: each 100-150ml, every day 2 times, 2 days courses for the treatment of.
embodiment 2cure a preparation for acute urethritis, take off and state primary raw material and be prepared from (getting 30g for every part): Caulis Akebiae 10 parts; Herba mazi japonici 14 parts; Lignum et Radix Naucleae 15 parts; Herba bidentis parviflorae 16 parts; Folium Pruni pseudocerasi 15 parts; Petiolus nelumbinis 16 parts; The Fructus Kochiae 14 parts; Radix Chimonanthi praecocis 13 parts; 14 parts, cliff lotus; Rhizoma Homalomenae 13 parts; Herba Lophatheri 17 parts; Herba Nanocnides Japonicae 16 parts; Microsorium fortunei (Moore) ching 15 parts; Water hair penetrates 14 parts; Radix Zanthoxyli Planispini 15 parts.
Above-mentioned a kind of preparation method curing the preparation granules agent of acute urethritis, step is as follows:
(1) be placed in pot by Caulis Akebiae and the Fructus Kochiae, slow fire fries 25 minutes, mechanical activation comminution, crosses 140 mesh sieves;
(2) Folium Pruni pseudocerasi, Petiolus nelumbinis and Herba Lophatheri are cleaned, be placed in container, add water, moistening 4 hours, is placed in juicer, and strand juice, filters;
(3) Rhizoma Homalomenae, Microsorium fortunei (Moore) ching and Radix Zanthoxyli Planispini are cut into slices, be placed in glass container, add white vinegar (consumption is 35% of Rhizoma Homalomenae, Microsorium fortunei (Moore) ching and Radix Zanthoxyli Planispini gross mass), moistening 5 hours, take out, dry;
(4) Herba mazi japonici, Lignum et Radix Naucleae, Herba bidentis parviflorae, Radix Chimonanthi praecocis, cliff lotus, Herba Nanocnides Japonicae and water hair are penetrated clean, be placed in container, add water and cover powder 3cm, soak 50 minutes, take out, be placed in multi-function extractor, add step (3) gains, extracting in water twice, each extraction 45 minutes, merge extractive liquid, concentrated juice relative density is 1.05(25 DEG C) concentrated solution;
(5) step (1) gained fine powder is joined in step (4) gained concentrated solution, mixing, filter, add step (2) gained medicinal liquid, stir 3 minutes, filter, be concentrated into relative density 1.15(25 DEG C) thick paste, make uniform fine particle, be aided with pharmaceutically acceptable carrier package, the quality of every parcel is 6g.
Instructions of taking: each 1 bag, takes after melting, every day 2 times, 2 days courses for the treatment of by warm water.
model case onesong XX, man, 41 years old, people from Jining City in Shandong Province.Usually occur that uncomfortable, the slight pruritus of urethra, frequent micturition, urgent micturition, urethra burn the symptoms such as sample pain without starting under obvious inducement, thought originally and oneself obtained sexually transmitted disease (STD), be reluctant examination in hospital, oneself has bought some classes of anti-infective antibiotic medicine to pharmacy, and having taken symptom after a week, without improvement, has on the contrary and increase the weight of, often urethral orifice adularescent mucous secretions is found, so remove hospital admission, being nongonococcal urethritis by checkout and diagnosis, infusing after 4 days without obviously alleviating.
After taking the present invention a kind of 2 courses for the treatment of of preparation (embodiment 2) of curing acute urethritis, the symptom of urine urgency-frequency is obviously alleviated, the little adularescent mucus secretion of urethral orifice.After continuing to take 2 courses for the treatment of, all malaise symptoms are all obviously alleviated, and pruritis disappears.Later stage learns and fully recovers in following up a case by regular visits to, and does not occur the phenomenon of recurrent exerbation.
embodiment 3cure a preparation for acute urethritis, take off and state primary raw material and be prepared from (getting 50g for every part): Caulis Akebiae 7 parts; Herba mazi japonici 11 parts; Lignum et Radix Naucleae 12 parts; Herba bidentis parviflorae 11 parts; Folium Pruni pseudocerasi 11 parts; Petiolus nelumbinis 13 parts; The Fructus Kochiae 10 parts; Radix Chimonanthi praecocis 10 parts; 10 parts, cliff lotus; Rhizoma Homalomenae 9 parts; Herba Lophatheri 13 parts; Herba Nanocnides Japonicae 12 parts; Microsorium fortunei (Moore) ching 10 parts; Water hair penetrates 9 parts; Radix Zanthoxyli Planispini 11 parts.
Above-mentioned a kind of preparation method curing the preparation concentrated pill of acute urethritis, step is as follows:
(1) be placed in pot by Caulis Akebiae and the Fructus Kochiae, slow fire fries 25 minutes, mechanical activation comminution, crosses 140 mesh sieves;
(2) Folium Pruni pseudocerasi, Petiolus nelumbinis and Herba Lophatheri are cleaned, be placed in container, add water, moistening 4 hours, is placed in juicer, and strand juice, filters;
(3) Rhizoma Homalomenae, Microsorium fortunei (Moore) ching and Radix Zanthoxyli Planispini are cut into slices, be placed in glass container, add white vinegar (consumption is 35% of Rhizoma Homalomenae, Microsorium fortunei (Moore) ching and Radix Zanthoxyli Planispini gross mass), moistening 5 hours, take out, dry;
(4) Herba mazi japonici, Lignum et Radix Naucleae, Herba bidentis parviflorae, Radix Chimonanthi praecocis, cliff lotus, Herba Nanocnides Japonicae and water hair are penetrated clean, be placed in container, add water and cover powder 3cm, soak 50 minutes, take out, be placed in multi-function extractor, add step (3) gains, extracting in water twice, each extraction 45 minutes, merge extractive liquid, concentrated juice relative density is 1.05(25 DEG C) concentrated solution;
(5) step (1) gained fine powder is joined in step (4) gained concentrated solution, mixing, filter, add step (2) gained medicinal liquid, stir 3 minutes, filter, be concentrated into relative density 1.15(25 DEG C) thick paste, the concentrated pill that diameter is 4mm is made, sterile packaged by standard pharmaceutically.
Using method: each 8 balls, with warm water delivery service, every day 2 times, 2 days courses for the treatment of.
embodiment 4cure a preparation for acute urethritis, take off and state primary raw material and be prepared from (getting 20g for every part): Caulis Akebiae 9 parts; Herba mazi japonici 13 parts; Lignum et Radix Naucleae 14 parts; Herba bidentis parviflorae 13 parts; Folium Pruni pseudocerasi 13 parts; Petiolus nelumbinis 15 parts; The Fructus Kochiae 12 parts; Radix Chimonanthi praecocis 12 parts; 12 parts, cliff lotus; Rhizoma Homalomenae 11 parts; Herba Lophatheri 15 parts; Herba Nanocnides Japonicae 14 parts; Microsorium fortunei (Moore) ching 12 parts; Water hair penetrates 11 parts; Radix Zanthoxyli Planispini 13 parts.
Above-mentioned a kind of preparation method curing the formulation tablet of acute urethritis, step is as follows:
(1) be placed in pot by Caulis Akebiae and the Fructus Kochiae, slow fire fries 25 clocks, mechanical activation comminution, crosses 140 mesh sieves;
(2) Folium Pruni pseudocerasi, Petiolus nelumbinis and Herba Lophatheri are cleaned, be placed in container, add water, moistening 4 hours, is placed in juicer, and strand juice, filters;
(3) Rhizoma Homalomenae, Microsorium fortunei (Moore) ching and Radix Zanthoxyli Planispini are cut into slices, be placed in glass container, add white vinegar (consumption is 35% of Rhizoma Homalomenae, Microsorium fortunei (Moore) ching and Radix Zanthoxyli Planispini gross mass), moistening 5 hours, take out, dry;
(4) Herba mazi japonici, Lignum et Radix Naucleae, Herba bidentis parviflorae, Radix Chimonanthi praecocis, cliff lotus, Herba Nanocnides Japonicae and water hair are penetrated clean, be placed in container, add water and cover powder 3cm, soak 50 minutes, take out, be placed in multi-function extractor, add step (3) gains, extracting in water twice, each extraction 45 minutes, merge extractive liquid, concentrated juice relative density is 1.05(25 DEG C) concentrated solution;
(5) step (1) gained fine powder is joined in step (4) gained concentrated solution, mixing, filter, add step (2) gained medicinal liquid, stir 3 minutes, filter, be concentrated into relative density 1.15(25 DEG C) thick paste, become tablet by metric system pharmaceutically, sugar coating.
Using method: each 2-3 sheet, every day 2 times, 2 days courses for the treatment of.
model case twobusiness XX, man, 24 years old, people from Suzhou City of Jiangsu Province.When occurred urgent micturition, dysurea symptom not knowing specifically from, urethra has burning sensation, play urethral orifice morning and usually have a small amount of viscous secretion, be in from taking medicine thing after 3 days, urgent micturition, frequent micturition are alleviated, but but find urethral orifice stream yellow pus sample secretions, and have gargalesthesia.So remove examination in hospital, be diagnosed as nongonococcal urethritis.After the treatment of a week, the remission of urgent micturition frequent micturition dysurea, urethral orifice still has a small amount of secretions to flow out, and perineum swelling sense disappears.But crossed less than one month, occurred discomfort again, and serious comparatively before.
The diseases such as after taking gained of the present invention a kind of 2 courses for the treatment of of preparation (embodiment 4) of curing acute urethritis, urethra is uncomfortable, itch, burn feeling, urodynamic, urethral orifice are red and swollen are obviously alleviated.After continuing to take 2 courses for the treatment of, every physical signs recovers normal, and all malaise symptoms disappear.Follow up a case by regular visits to so far nearly in year non-pouring do not recur so far.
embodiment 5cure a preparation for acute urethritis, take off and state primary raw material and be prepared from (getting 40g for every part): Caulis Akebiae 8 parts; Herba mazi japonici 12 parts; Lignum et Radix Naucleae 13 parts; Herba bidentis parviflorae 12 parts; Folium Pruni pseudocerasi 12 parts; Petiolus nelumbinis 14 parts; The Fructus Kochiae 11 parts; Radix Chimonanthi praecocis 11 parts; 11 parts, cliff lotus; Rhizoma Homalomenae 10 parts; Herba Lophatheri 14 parts; Herba Nanocnides Japonicae 13 parts; Microsorium fortunei (Moore) ching 11 parts; Water hair penetrates 10 parts; Radix Zanthoxyli Planispini 12 parts.
Above-mentioned a kind of preparation method curing the preparation capsule of acute urethritis, step is as follows:
(1) be placed in pot by Caulis Akebiae and the Fructus Kochiae, slow fire fries 25 minutes, mechanical activation comminution, crosses 140 mesh sieves;
(2) Folium Pruni pseudocerasi, Petiolus nelumbinis and Herba Lophatheri are cleaned, be placed in container, add water, moistening 4 hours, is placed in juicer, and strand juice, filters;
(3) Rhizoma Homalomenae, Microsorium fortunei (Moore) ching and Radix Zanthoxyli Planispini are cut into slices, be placed in glass container, add white vinegar (consumption is 35% of Rhizoma Homalomenae, Microsorium fortunei (Moore) ching and Radix Zanthoxyli Planispini gross mass), moistening 5 hours, take out, dry;
(4) Herba mazi japonici, Lignum et Radix Naucleae, Herba bidentis parviflorae, Radix Chimonanthi praecocis, cliff lotus, Herba Nanocnides Japonicae and water hair are penetrated clean, be placed in container, add water and cover powder 3cm, soak 50 minutes, take out, be placed in multi-function extractor, add step (3) gains, extracting in water twice, each extraction 45 minutes, merge extractive liquid, concentrated juice relative density is 1.05(25 DEG C) concentrated solution;
(5) step (1) gained fine powder is joined in step (4) gained concentrated solution, mixing, filter, add step (2) gained medicinal liquid, stir 3 minutes, filter, be concentrated into relative density 1.25(25 DEG C) thick paste, dry, pulverize, make capsule (0.5g/ grain).
Instructions of taking: each 2-3 grain, every day 2 times, 2 days courses for the treatment of.
test example:in order to verify a kind of curative effect curing the preparation (embodiment 5) of acute urethritis of the present invention, do contrast test in June ,-2011 in August, 2010:
General data: screening 260 routine acute urethritis patient, wherein minimal ages 18 years old, max age 66 years old, 39.6 years old mean age.Be divided into experimental group and matched group two groups (wherein experimental group 160 people, matched group 100 people) at random, two groups are compared there was no significant difference, have comparability in sex, age, the course of disease, state of an illness scoring etc.
Diagnostic criteria: 1. urethral stimulant symptom, urethral orifice is red and swollen, has purulent secretion, can have tenderness along urethra.2. have volume erythrocyte, leukocyte in urine, three-glass test first glass urine is obviously abnormal.3. the inspection of urethral secretions smear staining or antibacterial culturing have pathogenic bacterium.4., during urethra acute inflammation, external orifice of urethra is red and swollen, and edge turns up, mucomembranous surface often by serosity or purulent secretion bond, sometimes have fester.5. visible myxedema under mirror, wherein has leukocyte, plasma cell and lymphocytic infiltration, telangiectasis, paraurethral gland body congested or clog by pus cell in heaps.
Usage and dosage: experimental group takes a kind of preparation of curing acute urethritis of the present invention, each serving with 2, every day 2 times, 2 days courses for the treatment of; Matched group takes other medicine (example hydrochloric acid doxycycline tablet, erythromycin tablets), wherein, and doxycycline hydrochloride sheet a: 100mg, 2 times on the one, at least 7 days courses for the treatment of.Erythromycin tablets: oral, be grown up 0.75-2g on the one, divides 3-4 time, and child divides 3-4 time by body weight 20-40mg/kg every day.
Criterion of therapeutical effect: cure: subjective symptoms disappears, and urethral orifice is without rheuminess thing, and the symptoms such as frequent micturition, dysurea, urgent micturition, hematuria disappear completely, secretions smear negative.Effective: subjective symptoms alleviates, secretion of urethral orifice is a little, and the symptoms such as frequent micturition, dysurea, urgent micturition, hematuria are obviously alleviated, secretions smear negative.Invalid: symptom, without improvement, has no that sb.'s illness took a favorable turn.
Adopt the matched group of other drug and take a kind of Comparison of therapeutic curing the experimental group of the preparation of acute urethritis of the present invention, result is as shown in table 1:
Table 1
efficacy analysis:as can be seen from Table 1, take a kind of inefficiency curing the preparation of acute urethritis of the present invention and be only 2.5%, cure rate is up to 71.88%, effective percentage is up to 97.5%, and adopting the inefficiency had up to 18% of other treatment scheme, cure rate only reaches 38%, and effective percentage is also only 82%.Experiment shows that a kind of preparation of curing acute urethritis of the present invention is compared with other drug, and evident in efficacy, cure rate is high, and inefficiency is low, and be the more desirable medicament for the treatment of acute urethritis, clinic is extensively promoted the use of.
Finally it should be noted that, embodiment is the detailed description of the invention of optimum of the present invention, be not limited to the present invention, although with reference to previous embodiment to invention has been detailed description, for a person skilled in the art, it still can be modified to the technical scheme described in foregoing embodiments, or carries out equivalent replacement to wherein portion of techniques feature.Within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (10)
1. cure a preparation for acute urethritis, it is characterized in that, take off the primary raw material stating weight proportion and be prepared from: Caulis Akebiae 6-10 part; Herba mazi japonici 9-14 part; Lignum et Radix Naucleae 10-15 part; Herba bidentis parviflorae 8-16 part; Folium Pruni pseudocerasi 9-15 part; Petiolus nelumbinis 11-16 part; Fructus Kochiae 7-14 part; Radix Chimonanthi praecocis 9-13 part; Cliff lotus 8-14 part; Rhizoma Homalomenae 7-13 part; Herba Lophatheri 11-17 part; Herba Nanocnides Japonicae 9-16 part; Microsorium fortunei (Moore) ching 7-15 part; Water hair penetrates 6-14 part; Radix Zanthoxyli Planispini 8-15 part.
2. a kind of preparation according to claim 1, is characterized in that, takes off the primary raw material stating weight proportion and is prepared from: Caulis Akebiae 7-9 part; Herba mazi japonici 11-13 part; Lignum et Radix Naucleae 12-14 part; Herba bidentis parviflorae 11-13 part; Folium Pruni pseudocerasi 11-13 part; Petiolus nelumbinis 13-15 part; Fructus Kochiae 10-12 part; Radix Chimonanthi praecocis 10-12 part; Cliff lotus 10-12 part; Rhizoma Homalomenae 9-11 part; Herba Lophatheri 13-15 part; Herba Nanocnides Japonicae 12-14 part; Microsorium fortunei (Moore) ching 10-12 part; Water hair penetrates 9-11 part; Radix Zanthoxyli Planispini 11-13 part.
3. a kind of preparation according to claim 1, is characterized in that, takes off the primary raw material stating weight proportion and is prepared from: Caulis Akebiae 8 parts; Herba mazi japonici 12 parts; Lignum et Radix Naucleae 13 parts; Herba bidentis parviflorae 12 parts; Folium Pruni pseudocerasi 12 parts; Petiolus nelumbinis 14 parts; The Fructus Kochiae 11 parts; Radix Chimonanthi praecocis 11 parts; 11 parts, cliff lotus; Rhizoma Homalomenae 10 parts; Herba Lophatheri 14 parts; Herba Nanocnides Japonicae 13 parts; Microsorium fortunei (Moore) ching 11 parts; Water hair penetrates 10 parts; Radix Zanthoxyli Planispini 12 parts.
4., according to the arbitrary described preparation of claim 1-3, it is characterized in that: the preparation method of described decoction, step is as follows:
(1) be placed in pot by Caulis Akebiae and the Fructus Kochiae, slow fire fries 20-30 minute, mechanical activation comminution, excessively 130-150 mesh sieve (preferred 136-144 mesh sieve excessively, was more preferably 140 mesh sieves);
(2) Folium Pruni pseudocerasi, Petiolus nelumbinis and Herba Lophatheri are cleaned, be placed in container, add water, moistening 3-5 hour, is placed in juicer, and strand juice, filters;
(3) Rhizoma Homalomenae, Microsorium fortunei (Moore) ching and Radix Zanthoxyli Planispini are cut into slices, be placed in glass container, add white vinegar, moistening 4-6 hour, take out, dry;
(4) Herba mazi japonici, Lignum et Radix Naucleae, Herba bidentis parviflorae, Radix Chimonanthi praecocis, cliff lotus, Herba Nanocnides Japonicae and water hair are penetrated clean, be placed in container, add water and cover powder 2-3cm, soak 40-60 minute, take out, be placed in multi-function extractor, add step (3) gains, extracting in water twice, each extraction 40-50 minute (preferably each extraction 43-47 minute, be more preferably each extraction 45 minutes), merge extractive liquid, concentrated juice relative density is the concentrated solution of 1.00-1.10;
(5) step (1) gained fine powder is joined in step (4) gained concentrated solution, mixing, filter, add step (2) gained medicinal liquid, stir 2-3 minute, filter, sterile packaged.
5. the preparation method of preparation according to claim 4, it is characterized in that: the consumption of the preferred white vinegar of step (3) is 30%40% of Rhizoma Homalomenae, Microsorium fortunei (Moore) ching and Radix Zanthoxyli Planispini gross mass, and the consumption being more preferably white vinegar is 35% of Rhizoma Homalomenae, Microsorium fortunei (Moore) ching and Radix Zanthoxyli Planispini gross mass.
6., according to the arbitrary described preparation of claim 1-3, it is characterized in that: the preparation method of described granule, step is as follows:
(1) be placed in pot by Caulis Akebiae and the Fructus Kochiae, slow fire fries 20-30 minute, mechanical activation comminution, excessively 130-150 mesh sieve (preferred 136-144 mesh sieve excessively, was more preferably 140 mesh sieves);
(2) Folium Pruni pseudocerasi, Petiolus nelumbinis and Herba Lophatheri are cleaned, be placed in container, add water, moistening 3-5 hour, is placed in juicer, and strand juice, filters;
(3) Rhizoma Homalomenae, Microsorium fortunei (Moore) ching and Radix Zanthoxyli Planispini are cut into slices, be placed in glass container, (consumption of preferred white vinegar is 30%40% of Rhizoma Homalomenae, Microsorium fortunei (Moore) ching and Radix Zanthoxyli Planispini gross mass to add white vinegar, the consumption being more preferably white vinegar is 35% of Rhizoma Homalomenae, Microsorium fortunei (Moore) ching and Radix Zanthoxyli Planispini gross mass), moistening 4-6 hour, take out, dry;
(4) Herba mazi japonici, Lignum et Radix Naucleae, Herba bidentis parviflorae, Radix Chimonanthi praecocis, cliff lotus, Herba Nanocnides Japonicae and water hair are penetrated clean, be placed in container, add water and cover powder 2-3cm, soak 40-60 minute, take out, be placed in multi-function extractor, add step (3) gains, extracting in water twice, each extraction 40-50 minute (preferably each extraction 43-47 minute, be more preferably each extraction 45 minutes), merge extractive liquid, concentrated juice relative density is the concentrated solution of 1.00-1.10;
(5) step (1) gained fine powder is joined in step (4) gained concentrated solution, mixing, filter, add step (2) gained medicinal liquid, stir 2-3 minute, filter, be concentrated into the thick paste of relative density 1.10-1.20, make uniform fine particle, be aided with pharmaceutically acceptable carrier package, the quality of every parcel is 6g.
7. the preparation method of preparation according to claim 6, is characterized in that: step (5) is preferably concentrated into the thick paste of relative density 1.13-1.17, is more preferably the thick paste being concentrated into relative density 1.15.
8., according to the arbitrary described preparation of claim 1-3, it is characterized in that: the preparation method of described concentrated pill, step is as follows:
(1) be placed in pot by Caulis Akebiae and the Fructus Kochiae, slow fire fries 20-30 minute, mechanical activation comminution, excessively 130-150 mesh sieve (preferred 136-144 mesh sieve excessively, was more preferably 140 mesh sieves);
(2) Folium Pruni pseudocerasi, Petiolus nelumbinis and Herba Lophatheri are cleaned, be placed in container, add water, moistening 3-5 hour, is placed in juicer, and strand juice, filters;
(3) Rhizoma Homalomenae, Microsorium fortunei (Moore) ching and Radix Zanthoxyli Planispini are cut into slices, be placed in glass container, (consumption of preferred white vinegar is 30%40% of Rhizoma Homalomenae, Microsorium fortunei (Moore) ching and Radix Zanthoxyli Planispini gross mass to add white vinegar, the consumption being more preferably white vinegar is 35% of Rhizoma Homalomenae, Microsorium fortunei (Moore) ching and Radix Zanthoxyli Planispini gross mass), moistening 4-6 hour, take out, dry;
(4) Herba mazi japonici, Lignum et Radix Naucleae, Herba bidentis parviflorae, Radix Chimonanthi praecocis, cliff lotus, Herba Nanocnides Japonicae and water hair are penetrated clean, be placed in container, add water and cover powder 2-3cm, soak 40-60 minute, take out, be placed in multi-function extractor, add step (3) gains, extracting in water twice, each extraction 40-50 minute (preferably each extraction 43-47 minute, be more preferably each extraction 45 minutes), merge extractive liquid, concentrated juice relative density is the concentrated solution of 1.00-1.10;
(5) step (1) gained fine powder is joined in step (4) gained concentrated solution, mixing, filter, add step (2) gained medicinal liquid, stir 2-3 minute, filter, be concentrated into the thick paste (be preferably concentrated into the thick paste of relative density 1.13-1.17, be more preferably the thick paste being concentrated into relative density 1.15) of relative density 1.10-1.20, (preferred diameter is 3-5mm to make concentrated pill by standard pharmaceutically, being more preferably diameter is 4mm), sterile packaged.
9., according to the arbitrary described preparation of claim 1-3, it is characterized in that: the preparation method of described tablet, step is as follows:
(1) be placed in pot by Caulis Akebiae and the Fructus Kochiae, slow fire fries 20-30 minute, mechanical activation comminution, excessively 130-150 mesh sieve (preferred 136-144 mesh sieve excessively, was more preferably 140 mesh sieves);
(2) Folium Pruni pseudocerasi, Petiolus nelumbinis and Herba Lophatheri are cleaned, be placed in container, add water, moistening 3-5 hour, is placed in juicer, and strand juice, filters;
(3) Rhizoma Homalomenae, Microsorium fortunei (Moore) ching and Radix Zanthoxyli Planispini are cut into slices, be placed in glass container, (consumption of preferred white vinegar is 30%40% of Rhizoma Homalomenae, Microsorium fortunei (Moore) ching and Radix Zanthoxyli Planispini gross mass to add white vinegar, the consumption being more preferably white vinegar is 35% of Rhizoma Homalomenae, Microsorium fortunei (Moore) ching and Radix Zanthoxyli Planispini gross mass), moistening 4-6 hour, take out, dry;
(4) Herba mazi japonici, Lignum et Radix Naucleae, Herba bidentis parviflorae, Radix Chimonanthi praecocis, cliff lotus, Herba Nanocnides Japonicae and water hair are penetrated clean, be placed in container, add water and cover powder 2-3cm, soak 40-60 minute, take out, be placed in multi-function extractor, add step (3) gains, extracting in water twice, each extraction 40-50 minute (preferably each extraction 43-47 minute, be more preferably each extraction 45 minutes), merge extractive liquid, concentrated juice relative density is the concentrated solution of 1.00-1.10;
(5) step (1) gained fine powder is joined in step (4) gained concentrated solution, mixing, filter, add step (2) gained medicinal liquid, stir 2-3 minute, filter, the thick paste being concentrated into relative density 1.10-1.20 (is preferably concentrated into the thick paste of relative density 1.13-1.17, be more preferably the thick paste being concentrated into relative density 1.15), become tablet by metric system pharmaceutically, sugar coating.
10., according to the arbitrary described preparation of claim 1-3, it is characterized in that: the preparation method of described capsule, step is as follows:
(1) be placed in pot by Caulis Akebiae and the Fructus Kochiae, slow fire fries 20-30 minute, mechanical activation comminution, excessively 130-150 mesh sieve (preferred 136-144 mesh sieve excessively, was more preferably 140 mesh sieves);
(2) Folium Pruni pseudocerasi, Petiolus nelumbinis and Herba Lophatheri are cleaned, be placed in container, add water, moistening 3-5 hour, is placed in juicer, and strand juice, filters;
(3) Rhizoma Homalomenae, Microsorium fortunei (Moore) ching and Radix Zanthoxyli Planispini are cut into slices, be placed in glass container, (consumption of preferred white vinegar is 30%40% of Rhizoma Homalomenae, Microsorium fortunei (Moore) ching and Radix Zanthoxyli Planispini gross mass to add white vinegar, the consumption being more preferably white vinegar is 35% of Rhizoma Homalomenae, Microsorium fortunei (Moore) ching and Radix Zanthoxyli Planispini gross mass), moistening 4-6 hour, take out, dry;
(4) Herba mazi japonici, Lignum et Radix Naucleae, Herba bidentis parviflorae, Radix Chimonanthi praecocis, cliff lotus, Herba Nanocnides Japonicae and water hair are penetrated clean, be placed in container, add water and cover powder 2-3cm, soak 40-60 minute, take out, be placed in multi-function extractor, add step (3) gains, extracting in water twice, each extraction 40-50 minute (preferably each extraction 43-47 minute, be more preferably each extraction 45 minutes), merge extractive liquid, concentrated juice relative density is the concentrated solution of 1.00-1.10;
(5) step (1) gained fine powder is joined in step (4) gained concentrated solution, mixing, filters, adds step (2) gained medicinal liquid, stir 2-3 minute, filter, be concentrated into the thick paste (be preferably concentrated into the thick paste of relative density 1.23-1.27, be more preferably the thick paste being concentrated into relative density 1.25) of relative density 1.20-1.30, dry, pulverize, make capsule (preferred 0.4-0.6g/ grain, is more preferably 0.5g/ grain).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510653410.0A CN105194382A (en) | 2015-10-12 | 2015-10-12 | Preparation for treating urethritis and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510653410.0A CN105194382A (en) | 2015-10-12 | 2015-10-12 | Preparation for treating urethritis and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105194382A true CN105194382A (en) | 2015-12-30 |
Family
ID=54942567
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510653410.0A Withdrawn CN105194382A (en) | 2015-10-12 | 2015-10-12 | Preparation for treating urethritis and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105194382A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114246868A (en) * | 2021-12-24 | 2022-03-29 | 中国人民解放军军事科学院军事医学研究院 | Inhibitor of urinary tract infection pathogen uropathogenic escherichia coli |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101537137A (en) * | 2009-04-28 | 2009-09-23 | 徐樊 | Chinese material medical preparation for treating urinary infection |
| CN101954011A (en) * | 2010-10-09 | 2011-01-26 | 曹峻岭 | Chinese medicinal preparation for treating urethritis |
| CN102743663A (en) * | 2012-07-24 | 2012-10-24 | 广州海博特医药科技有限公司 | Chinese medicinal preparation for treating urinary infection and preparation method thereof |
| CN103977296A (en) * | 2014-06-02 | 2014-08-13 | 张玮玮 | Traditional Chinese medicine oral solution for treating urethritis and preparation method thereof |
-
2015
- 2015-10-12 CN CN201510653410.0A patent/CN105194382A/en not_active Withdrawn
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101537137A (en) * | 2009-04-28 | 2009-09-23 | 徐樊 | Chinese material medical preparation for treating urinary infection |
| CN101954011A (en) * | 2010-10-09 | 2011-01-26 | 曹峻岭 | Chinese medicinal preparation for treating urethritis |
| CN102743663A (en) * | 2012-07-24 | 2012-10-24 | 广州海博特医药科技有限公司 | Chinese medicinal preparation for treating urinary infection and preparation method thereof |
| CN103977296A (en) * | 2014-06-02 | 2014-08-13 | 张玮玮 | Traditional Chinese medicine oral solution for treating urethritis and preparation method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 罗武: "《家庭常用中药 药性与处方》", 31 March 1995 * |
| 蔡玉华等: "《实用男女病性病临床手册》", 31 July 1996 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114246868A (en) * | 2021-12-24 | 2022-03-29 | 中国人民解放军军事科学院军事医学研究院 | Inhibitor of urinary tract infection pathogen uropathogenic escherichia coli |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101347594B (en) | Method for preparing Chinese medicine for treating kidney-yang deficiency type diarrhea | |
| CN105194382A (en) | Preparation for treating urethritis and preparation method thereof | |
| CN104056242A (en) | Traditional Chinese medicine composition for treating acute cholecystitis and preparation method thereof | |
| CN103877457B (en) | Chinese medicinal preparation for treating renal calculus and preparation method thereof | |
| CN104225344A (en) | Chinese herbal preparation for treating chronic nephropyelitis and preparation method thereof | |
| CN104758705A (en) | Traditional Chinese medicine composition for treating chronic glomerulo nephritis and preparation method thereof | |
| CN103989836A (en) | Traditional Chinese medicine preparation for treating appendicitis and preparation method thereof | |
| CN104771585A (en) | Traditional Chinese medicine composition for treating acute nephritis and preparation method thereof | |
| CN104225569A (en) | Chinese medicinal composition for treating chronic enteritis | |
| CN104324201A (en) | Traditional Chinese medicine preparation for treating urinary system infection and production method | |
| CN104096103A (en) | Traditional Chinese medicine agent for treating uroschesis | |
| CN103845718A (en) | Medicine for treating cough and asthma and preparation method thereof | |
| CN103432335B (en) | Medicament for treating chyluria and preparation method thereof | |
| CN106491949A (en) | A kind of Chinese medicine formula for treating chronic pharyngitiss | |
| CN105770354A (en) | Medicament for treating chronic nephritis and preparation method thereof | |
| CN104622983A (en) | Traditional Chinese medicine composition for treating proctitis and preparation method thereof | |
| CN104784406A (en) | Traditional Chinese medicine composition for treating rectal cancer and preparation method | |
| CN104784563A (en) | Traditional Chinese medicine preparation for treating amygdalitis and preparation method thereof | |
| CN105267732A (en) | Oral prescription for treatment of urethritis and preparation method | |
| CN104857255A (en) | Traditional Chinese medicine preparation for treating suppurative otitis media and preparation method | |
| CN104825980A (en) | Traditional Chinese medicine preparation for treating diarrhea | |
| CN104771705A (en) | Traditional Chinese medicine preparation for treating chronic nephritis | |
| CN104721670A (en) | TCM (traditional Chinese medicine) composition for treating Laryngopharyngitis and preparing method thereof | |
| CN105194027A (en) | Composition for treating urethritis and preparation method thereof | |
| CN105288129A (en) | Traditional Chinese medicine composition for preventing and treating nephrotic syndrome and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| CB02 | Change of applicant information |
Address after: 037000 Shanxi City, Datong East Road, No. 3, building 2, unit 302, 43 Applicant after: Chen Yun Address before: 250000 Shandong Province Flyover District of Ji'nan City shadowless Hill Road No. 102 Applicant before: Chen Yun |
|
| CB02 | Change of applicant information | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20151230 |
|
| WW01 | Invention patent application withdrawn after publication |