CN105193861A - Novel softening and cutting method in traditional Chinese medicine preparing process - Google Patents
Novel softening and cutting method in traditional Chinese medicine preparing process Download PDFInfo
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- CN105193861A CN105193861A CN201510659122.6A CN201510659122A CN105193861A CN 105193861 A CN105193861 A CN 105193861A CN 201510659122 A CN201510659122 A CN 201510659122A CN 105193861 A CN105193861 A CN 105193861A
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Abstract
The invention discloses a novel softening and cutting method in the traditional Chinese medicine preparing process, and relates to the field of traditional Chinese medicine decoction piece preparation. According to the method, a traditional Chinese medicinal material is treated by adopting a vacuum sealed decompression softening method, the osmotic pressure inside the tissue of a traditional Chinese medicinal material can be enhanced, and the affinity between the medicinal material and water is improved; the surface color of a medicinal material softened by the method is darker than that of the original medicinal material, no water-injury or sticky phenomenon occurs, the decoction pieces have high softening speed, good effect, appropriate softness and no white or hard core in the section, and the aim that water is used up when a medicine is infiltrated can be achieved. The decoction pieces are convenient to cut, process parameters, such as water addition, moistening time and the like, in the softening step can be easily controlled, and water-soluble ingredients cannot be easily lost.
Description
Technical field
The present invention relates to the prepared slices of Chinese crude drugs and concoct field, particularly softening cutting new method in a kind of Chinese crude drug concocting process.
Background technology
The softening cutting of Chinese crude drug is a link very crucial in process of preparing process.Softening improper, medical material can be caused " to hinder water " or " hard-core ".Medical material is excessively soft, then cutting flap-type is not good, and water soluble ingredient easily runs off or overflow in medical material surface; Medical material is not softening, makes to produce too much chip in cutting process, causes the waste of drug resource, affect the stripping etc. of effective ingredient.Chinese crude drug concocts the quality directly affecting decoction pieces, and the quality of prepared slice quality can be related to again effectiveness and the safety of tcm clinical practice medication.The traditional method that Chinese crude drug softens has moistening method, namely Hui Run and wet mass lid profit point, but it is consuming time longer that traditional Chinese crude drug softens cutting process, technique is loaded down with trivial details, owing to differing to the grasp of amount of water and damp time length in actual mechanical process, its processing procedure is still stagnated in experience level of control, extremely inadaptable with Development of Modern Science level, cause the loss of effective ingredient in Chinese crude drug often to differ greatly, be difficult to ensure its prepared slice quality and clinical efficacy, in all processed products of Chinese crude drug, tcm clinical practice form with the most use is just decoction pieces form, and the form of the various process of preparing Chinese medicine is all carry out on the basis of decoction pieces, the quality of the prepared slices of Chinese crude drugs has vital effect for the quality good or not of its each processed product.The standardized study of process of preparing has very important meaning.
Summary of the invention
The object of the invention is to avoid the deficiencies in the prior art, the new method of softening cutting in a kind of Chinese crude drug concocting process is provided.
A new method for softening cutting in Chinese crude drug concocting process, comprises the following steps:
Get selected Chinese crude drug, remove impurity, silt, for subsequent use, after Chinese crude drug is robbed water washing fast, in neat loading Polythene Bag, add 1-1.5 times of distilled water of Chinese crude drug weight, this packaging decompression (0.5-0.8kpa) vacuum-pumping density is honored as a queen ultrasonic softening, supersonic frequency is 60-100Hz, ultrasonic temperature 25-40 DEG C; Soften to after without the dry heart, hard-core until medical material, take out, cut into the thin slice of 1 ~ 2mm, the prepared slices of Chinese crude drugs good for cutting are dried in the shade under room temperature lucifuge condition.
Further, described Chinese crude drug is: Radix Angelicae Sinensis, the Radix Astragali, Radix Codonopsis, Radix Et Rhizoma Rhei, Radix Glycyrrhizae.
The invention has the beneficial effects as follows: the present invention adopts vacuum tightness decompression tenderizer process Chinese crude drug, not only enhance the osmotic pressure of drug entities inside, and facilitate the affinity of medicine and water, medical material slowly initiatively water absorption course become and suppress the lower passive water suction of impact, make water be obtained for significant increase in the inner speed that distributes of drug entities and the uniformity.The method soften after medical material surface color comparatively crude drug is dark slightly, nothing hinders water, the phenomenon that is clamminess occurs, softening rate is fast, effective, soft or hard is suitable for, and section is without the white heart, hard-core, really reach " medicine is permeable to the greatest extent ", be convenient to cutting, and the technological parameter such as amount of water, profit time processed in softening link is easy to control, and water soluble ingredient not easily runs off.
Detailed description of the invention
Embodiment 1
Get 1.0kg Radix Angelicae Sinensis, remove impurity, silt, for subsequent use, after Radix Angelicae Sinensis is robbed water washing fast, in neat loading Polythene Bag, add 1.5kg distilled water, be honored as a queen ultrasonic softening by this packaging decompression (0.8kpa) vacuum-pumping density, supersonic frequency is 60Hz, ultrasonic temperature 25 DEG C; Soften to after without the dry heart, hard-core until medical material, take out, cut into the thin slice of 1mm, the prepared slices of Chinese crude drugs good for cutting are dried in the shade under room temperature lucifuge condition.
Angelica sinensis extract content detects:
According to 2010 editions official methods, hot dipping is used to measure.Embodiment 1 does 5 groups of parallel tests, and testing result is as shown in table 1.
Table 1
Extract content testing result shows that the stability of the angelica sinensis that the softening cutting method that the present invention adopts is produced obviously is better than the decoction pieces of traditional handicraft production, and extractum output is high.The angelica sinensis prepared by the inventive method makes medicine, and drug quality is ensured, efficacy stability, and patient medication is safer.
Angelica sinensis measurement of the polysaccharide content:
Ultraviolet spectrophotometry is adopted to carry out polysaccharide component detection.Embodiment 1 does 5 groups of parallel tests, and testing result is as shown in table 2.
Table 2
Radix Angelicae Sinensis polysaccharide composition detection result shows that in angelica sinensis prepared by the inventive method, polyoses content is high, and stable content, is suitable for making medicine.
Ferulic acid, ligustilide assay in angelica sinensis:
HPLC method is adopted to carry out ferulic acid, ligustilide assay.Embodiment 1 does 5 groups of parallel tests, and testing result is as table 3
Table 3
Radix Angelicae Sinensis ferulic acid, ligustilide assay testing result show that angelica sinensis active constituent content prepared by the inventive method is high, and stable content, are suitable for making medicine.
Embodiment 2
Get the 1.5kg Radix Astragali, remove impurity, silt, for subsequent use, after the Radix Astragali is robbed water washing fast, in neat loading Polythene Bag, add 2.25kg distilled water, be honored as a queen ultrasonic softening by this packaging decompression (0.5kpa) vacuum-pumping density, supersonic frequency is 80Hz, ultrasonic temperature 30 DEG C; Soften to after without the dry heart, hard-core until medical material, take out, cut into the thin slice of 1.5mm, the prepared slices of Chinese crude drugs good for cutting are dried in the shade under room temperature lucifuge condition.
Embodiment 3
Get 5.0kg Radix Codonopsis, remove impurity, silt, for subsequent use, after the Radix Astragali is robbed water washing fast, in neat loading Polythene Bag, add 5.0kg distilled water, be honored as a queen ultrasonic softening by this packaging decompression (0.6kpa) vacuum-pumping density, supersonic frequency is 70Hz, ultrasonic temperature 35 DEG C; Soften to after without the dry heart, hard-core until medical material, take out, cut into the thin slice of 2mm, the prepared slices of Chinese crude drugs good for cutting are dried in the shade under room temperature lucifuge condition.
Embodiment 4
Get 3.0kg Radix Et Rhizoma Rhei, remove impurity, silt, for subsequent use, after Radix Et Rhizoma Rhei is robbed water washing fast, in neat loading Polythene Bag, add 4.5kg distilled water, be honored as a queen ultrasonic softening by this packaging decompression (0.7kpa) vacuum-pumping density, supersonic frequency is 100Hz, ultrasonic temperature 40 DEG C; Soften to after without the dry heart, hard-core until medical material, take out, cut into the thin slice of 1.5mm, the prepared slices of Chinese crude drugs good for cutting are dried in the shade under room temperature lucifuge condition.
Claims (2)
1. a new method for softening cutting in Chinese crude drug concocting process, is characterized in that: comprise the following steps:
Get selected Chinese crude drug, remove impurity, silt, for subsequent use, after Chinese crude drug is robbed water washing fast, in neat loading Polythene Bag, add 1-1.5 times of distilled water of Chinese crude drug weight, this packaging decompression (0.5-0.8kpa) vacuum-pumping density is honored as a queen ultrasonic softening, supersonic frequency is 60-100Hz, ultrasonic temperature 25-40 DEG C; Soften to after without the dry heart, hard-core until medical material, take out, cut into the thin slice of 1 ~ 2mm, the prepared slices of Chinese crude drugs good for cutting are dried in the shade under room temperature lucifuge condition.
2. the new method of softening cutting in a kind of Chinese crude drug concocting process according to claim 1, is characterized in that: Chinese crude drug Chinese crude drug is: Radix Angelicae Sinensis, the Radix Astragali, Radix Codonopsis, Radix Et Rhizoma Rhei, Radix Glycyrrhizae.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510659122.6A CN105193861A (en) | 2015-10-14 | 2015-10-14 | Novel softening and cutting method in traditional Chinese medicine preparing process |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510659122.6A CN105193861A (en) | 2015-10-14 | 2015-10-14 | Novel softening and cutting method in traditional Chinese medicine preparing process |
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| CN105193861A true CN105193861A (en) | 2015-12-30 |
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| CN201510659122.6A Pending CN105193861A (en) | 2015-10-14 | 2015-10-14 | Novel softening and cutting method in traditional Chinese medicine preparing process |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107582617A (en) * | 2017-10-13 | 2018-01-16 | 河南省三禾药业有限公司 | Radix glycyrrhizae is cut into slices and radix glycyrrhizae fresh-cut technique |
| CN108158813A (en) * | 2017-11-29 | 2018-06-15 | 宁夏百草王药业有限公司 | Tcm and herbal slice processing spraying demulcen softening process |
| CN108703884A (en) * | 2018-08-17 | 2018-10-26 | 湖南药圣堂中药科技有限公司 | A kind of quick demulcen softening sterilizing methods and its device of prepared slices of Chinese crude drugs processing |
| CN109172630A (en) * | 2018-09-10 | 2019-01-11 | 陕西昊源中药饮片有限公司 | A kind of processing procedure of preparing astragalus membranaceus |
| CN109893447A (en) * | 2019-04-04 | 2019-06-18 | 亳州华宇中药饮片有限公司 | A kind of softening method before Chinese medicine cutting |
-
2015
- 2015-10-14 CN CN201510659122.6A patent/CN105193861A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107582617A (en) * | 2017-10-13 | 2018-01-16 | 河南省三禾药业有限公司 | Radix glycyrrhizae is cut into slices and radix glycyrrhizae fresh-cut technique |
| CN108158813A (en) * | 2017-11-29 | 2018-06-15 | 宁夏百草王药业有限公司 | Tcm and herbal slice processing spraying demulcen softening process |
| CN108703884A (en) * | 2018-08-17 | 2018-10-26 | 湖南药圣堂中药科技有限公司 | A kind of quick demulcen softening sterilizing methods and its device of prepared slices of Chinese crude drugs processing |
| CN109172630A (en) * | 2018-09-10 | 2019-01-11 | 陕西昊源中药饮片有限公司 | A kind of processing procedure of preparing astragalus membranaceus |
| CN109893447A (en) * | 2019-04-04 | 2019-06-18 | 亳州华宇中药饮片有限公司 | A kind of softening method before Chinese medicine cutting |
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| C06 | Publication | ||
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| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20151230 |
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| WD01 | Invention patent application deemed withdrawn after publication |