CN105169270A - Medicine for promoting NSCLC (non-small-cell lung cancer) postoperative recovery, preparation method and application method - Google Patents

Medicine for promoting NSCLC (non-small-cell lung cancer) postoperative recovery, preparation method and application method Download PDF

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CN105169270A
CN105169270A CN201510648893.5A CN201510648893A CN105169270A CN 105169270 A CN105169270 A CN 105169270A CN 201510648893 A CN201510648893 A CN 201510648893A CN 105169270 A CN105169270 A CN 105169270A
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parts
radix
medicine
decoct
lung cancer
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郑晨昭
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Abstract

The invention provides a medicine for promoting NSCLC (non-small-cell lung cancer) postoperative recovery, a preparation method and an application method. The medicine comprises components in parts by weight as follows: 20-40 parts of coastal glehnia root, 10-20 parts of dwarf lilyturf tuber, 10-15 parts of schisandra chinensis, 28-32 parts of astragalus, 25-33 parts of hairyvein agrimonia herb, 8-12 parts of atractylodes rhizome, 17-25 parts of poria cocos, 10-15 parts of costazia bone, 22-40 parts of salvia miltiorrhiza, 9-15 parts of rhizoma curcumae, 9-18 parts of rhizoma sparganii, 28-35 parts of dried rehmannia and 2-10 parts of liquorice, water is added to the components for decoction, and the medicine is prepared. The medicine is prepared from traditional Chinese medicines, is low in cost, has good curative effect for NSCLC postoperative recovery and overcomes the defects of palliatives and undesirable effects in the prior art; the decocted medicine can be divided into two parts including a medicine soup part and a medicine residue part, the medicine soup is divided into a direct drinking part and a spraying part, the direct drinking part is taken before or after a meal within 30 min, the spraying part is sprayed into the oral cavity every 20-30 min at ordinary times, and the medicine residue part is used for external application for coordination treatment.

Description

A kind of medicine, preparation method and using method promoting nonsmall-cell lung cancer post-operative recovery
Technical field
The present invention relates to medical oncology technical field, particularly relate to a kind of treat Excision of Malignant Tumors after contribute to the Chinese patent medicine that recovers, specifically refer to a kind of medicine, preparation method and the using method that promote nonsmall-cell lung cancer post-operative recovery.
Background technology
Nonsmall-cell lung cancer is the malignant tumor that M & M is the highest, in the cause of death caused by tumor, ranked first position.At present, the primary treatments of nonsmall-cell lung cancer remains chemotherapy.But the side effect of chemotherapy is very large, because it also has stronger lethal effect to normal cell while killing tumor cell, a lot of tumor patient cannot tolerate the chemotherapy of larger dose and cause treatment to continue and dead.
The basic reason producing pulmonary carcinoma is that human righteousness is not enough, the evil poison of impression, and invade lung in evil poison, mechanism of qi is obstructed, the turbid interior life of expectorant, and blood vessels are stopped up stagnant, forms lump for a long time, sends out for this reason sick.Its pathogenesis many genus Primary Asthenia-Secondary Sthenia Syndrome, mark is real in pyretic toxicity, stagnation of phlegm, blood stasis, and deficiency in origin is based on insufficiency of vital energy and blood.Current pulmonary carcinoma is main mainly with chemotherapy greatly, and the large and weak curative effect of toxic and side effects, the effective ingredient rate of transform of decocting medicine is low, and weak curative effect, takes inconvenience.
Mostly be for current pulmonary carcinoma suggestion and early find, early treatment, hands art in advance, the development again of containment morbid state as early as possible, as a Cardiac surgeon, find in the clinical practice for the treatment of pulmonary carcinoma, postoperative patients with lung cancer shows as deficiency of qi and yin more, the internal resistance of the expectorant stasis of blood is demonstrate,proved, pathogenesis is complicated, although have some Western medicine for present situation, but Western medicine has the pathology treatment method of Western medicine, for the people of the different state of an illness, if blindly used, can have side effects, great disease is brought to health, such drug price is relatively high besides, for ordinary people, a kind of economic pressures, but, lack easy the to be honest and clean Chinese medicine preparation tested for this type of patient at present, the Chinese medicine formula of more existing treatment nonsmall-cell lung cancers can not directly use again at present.
Summary of the invention
The technical problem to be solved in the present invention is for the weak point existing for prior art, a kind of medicine promoting nonsmall-cell lung cancer post-operative recovery is provided, this medicine adopts Chinese medicine to make, cheap, good curative effect is had to nonsmall-cell lung cancer post-operative recovery, overcome in prior art cure the symptoms, not the disease, defect that effect is undesirable, nonsmall-cell lung cancer post-operative recovery is fast to adopt gained medicine of the present invention to promote, effective.
In addition, although this medicine composition is Chinese medicine formula, its preparation method is also innovative point of the present invention with taking mode, make drug effect maximize release, and maximization is used for the treatment of, good effect.
After this drug decocting, medicine can be divided into two parts, medicine soup part and medicinal residues part, medicine soup is divided into again straight drink part and blowing portion, straight drink part is used for taking in ante cibum or 30 minutes after meal, blowing portion at ordinary times every 20 ~ 30 minutes mouthsprays once, medicinal residues part then for external application, partner treatment.
Technical solution of the present invention is, following a kind of medicine promoting nonsmall-cell lung cancer post-operative recovery is provided, calculate by weight, comprise: Radix Glehniae 20 ~ 40 parts, Radix Ophiopogonis 10 ~ 20 parts, Fructus Schisandrae Chinensis 10 ~ 15 parts, the Radix Astragali 28 ~ 32 parts, Herba Agrimoniae 25 ~ 33 parts, Rhizoma Atractylodis 8 ~ 12 parts, 17 ~ 25 parts, Poria, Pumex 10 ~ 15 parts, Radix Salviae Miltiorrhizae 22 ~ 40 parts, Rhizoma Curcumae 9 ~ 15 parts, Rhizoma Sparganii 9 ~ 18 parts, 28 ~ 35 parts, the Radix Rehmanniae and 2 ~ 10 parts, Radix Glycyrrhizae, decoct with water and form.
As preferably, a kind of medicine promoting nonsmall-cell lung cancer post-operative recovery, calculate by weight, also comprise: Radix Fissistigmatis Glaucescentis 20 ~ 45 parts, Radix Platycodonis 8 ~ 16 parts, Radix Ginseng 10 ~ 13 parts, 18 ~ 40 parts, Nidus Vespae, queen bee breast 9 ~ 15 parts, 3 ~ 9 parts, Bulbus Allii, Corm Eleocharitis 12 ~ 17 parts, Germinatus Phragmitis 3 ~ 9 parts, 9 ~ 17 parts, Fructus Citri Limoniae, Fructus Jujubae 3 ~ 9 parts, Scolopendra 7 ~ 18 parts, Gekko Swinhonis 12 ~ 19 parts, arsenicum 0.01 ~ 0.1 part, Radix Semiaquilegiae 12 ~ 18 parts, Herba Scutellariae Barbatae 18 ~ 35 parts, Radix Notoginseng 12 ~ 19 parts, Herba Selaginellae Doederleinii 13 ~ 19 parts, the Radix Astragali 20 ~ 26 parts, Pseudobulbus Cremastrae Seu Pleiones 11 ~ 16 parts, Folium Digitalis Lanatae 15 ~ 30 parts, Concha Ostreae 1 ~ 10 part, Spica Prunellae 2 ~ 9 parts, JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata) 8 ~ 17 parts, Radix Patriniae heterophyllae 20 ~ 22 parts, Rhizoma Paridis 12 ~ 17 parts, Herba Solani Lyrati 12 ~ 19 parts, saponin 12 ~ 24 parts, Herba Hedyotidis Diffusae 20 ~ 30 parts, Borneolum Syntheticum 8 ~ 12 parts, the Radix Angelicae Dahuricae 6 ~ 10 parts, Pheretima 5 ~ 10 parts, Radix Et Rhizoma Rhei 2 ~ 9 parts of Flos Carthami 3 ~ 10 parts.
As preferably, a kind of medicine promoting nonsmall-cell lung cancer post-operative recovery, calculate by weight, comprise: Radix Glehniae 30 parts, Radix Ophiopogonis 15 parts, Fructus Schisandrae Chinensis 12 parts, the Radix Astragali 30 parts, Herba Agrimoniae 30 parts, Rhizoma Atractylodis 9 parts, 20 parts, Poria, Pumex 12 parts, Radix Salviae Miltiorrhizae 30 parts, Rhizoma Curcumae 12 parts, Rhizoma Sparganii 12 parts, 30 parts, the Radix Rehmanniae, 6 parts, Radix Glycyrrhizae, Radix Fissistigmatis Glaucescentis 30 parts, Radix Platycodonis 10 parts, Radix Ginseng 12 parts, 28 parts, Nidus Vespae, queen bee breast 11 parts, 5 parts, Bulbus Allii, Corm Eleocharitis 16 parts, Germinatus Phragmitis 5 parts, 15 parts, Fructus Citri Limoniae, Fructus Jujubae 6 parts, Scolopendra 10 parts, Gekko Swinhonis 15 parts, arsenicum 0.05 part, Radix Semiaquilegiae 13 parts, Herba Scutellariae Barbatae 22 parts, Radix Notoginseng 15 parts, Herba Selaginellae Doederleinii 17 parts, the Radix Astragali 24 parts, Pseudobulbus Cremastrae Seu Pleiones 13 parts, Folium Digitalis Lanatae 28 parts, Concha Ostreae 6 parts, Spica Prunellae 4 parts, JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata) 15 parts, Radix Patriniae heterophyllae 21 parts, Rhizoma Paridis 15 parts, Herba Solani Lyrati 16 parts, saponin 18 parts, Herba Hedyotidis Diffusae 25 parts, Borneolum Syntheticum 10 parts, the Radix Angelicae Dahuricae 8 parts, Pheretima 6 parts, Radix Et Rhizoma Rhei 4 parts, 7 parts, Flos Carthami, decoct with water and form.
Promote a preparation method for the medicine of nonsmall-cell lung cancer post-operative recovery, comprise drug decocting.
Described drug decocting step is:
(1) Radix Glehniae 20 ~ 40 parts, Radix Ophiopogonis 10 ~ 20 parts, Fructus Schisandrae Chinensis 10 ~ 15 parts, the Radix Astragali 28 ~ 32 parts, Herba Agrimoniae 25 ~ 33 parts, Rhizoma Atractylodis 8 ~ 12 parts, 17 ~ 25 parts, Poria, Pumex 10 ~ 15 parts, Radix Salviae Miltiorrhizae 22 ~ 40 parts, Rhizoma Curcumae 9 ~ 15 parts, Rhizoma Sparganii 9 ~ 18 parts, 28 ~ 35 parts, the Radix Rehmanniae and 2 ~ 10 parts, Radix Glycyrrhizae are put into decoction vessel, and put into the clear water of 3L, spacious lid utilizes intense fire to decoct to seething with excitement latter 10 minutes;
(2) cover decoction vessel cover, utilize slow fire to keep the intrinsic pressure power of decoction vessel to decoct 5 minutes higher than the pressure durations of normal atmosphere 1.3 ~ 1.5 times;
(3) in time decocting vessel inside residue 1L medicine soup, stop heating, pressure to be released, open wide and decoct vessel cover, medicine soup is separated with medicinal residues.
Promote that the using method of the medicine of nonsmall-cell lung cancer post-operative recovery is as follows: a when medicine soup is cooled to 30 ~ 50 DEG C, a point morning and evening takes for twice, each 0.5L.
Detailed description of the invention
For ease of illustrating, below the medicine of promotion nonsmall-cell lung cancer post-operative recovery of the present invention, preparation method and using method are elaborated.
Embodiment 1:
A kind of medicine promoting nonsmall-cell lung cancer post-operative recovery, calculate by weight, comprise: Radix Glehniae 20 ~ 40 parts, Radix Ophiopogonis 10 ~ 20 parts, Fructus Schisandrae Chinensis 10 ~ 15 parts, the Radix Astragali 28 ~ 32 parts, Herba Agrimoniae 25 ~ 33 parts, Rhizoma Atractylodis 8 ~ 12 parts, 17 ~ 25 parts, Poria, Pumex 10 ~ 15 parts, Radix Salviae Miltiorrhizae 22 ~ 40 parts, Rhizoma Curcumae 9 ~ 15 parts, Rhizoma Sparganii 9 ~ 18 parts, 28 ~ 35 parts, the Radix Rehmanniae and 2 ~ 10 parts, Radix Glycyrrhizae, decoct with water and form.
Specific as follows:
Promote a preparation method for the medicine of nonsmall-cell lung cancer post-operative recovery, comprise drug decocting.
Described drug decocting step is:
(1) Radix Glehniae 20 ~ 40 parts, Radix Ophiopogonis 10 ~ 20 parts, Fructus Schisandrae Chinensis 10 ~ 15 parts, the Radix Astragali 28 ~ 32 parts, Herba Agrimoniae 25 ~ 33 parts, Rhizoma Atractylodis 8 ~ 12 parts, 17 ~ 25 parts, Poria, Pumex 10 ~ 15 parts, Radix Salviae Miltiorrhizae 22 ~ 40 parts, Rhizoma Curcumae 9 ~ 15 parts, Rhizoma Sparganii 9 ~ 18 parts, 28 ~ 35 parts, the Radix Rehmanniae and 2 ~ 10 parts, Radix Glycyrrhizae are put into decoction vessel, and put into the clear water of 3L, spacious lid utilizes intense fire to decoct to seething with excitement latter 10 minutes;
(2) cover decoction vessel cover, utilize slow fire to keep the intrinsic pressure power of decoction vessel to decoct 5 minutes higher than the pressure durations of normal atmosphere 1.3 ~ 1.5 times;
(3) in time decocting vessel inside residue 1L medicine soup, stop heating, pressure to be released, open wide and decoct vessel cover, medicine soup is separated with medicinal residues.
Promote that the using method of the medicine of nonsmall-cell lung cancer post-operative recovery is as follows: a when medicine soup is cooled to 30 ~ 50 DEG C, a point morning and evening takes for twice, each 0.5L.
Embodiment 2:
Promote a medicine for nonsmall-cell lung cancer post-operative recovery, calculate by weight, comprising: Radix Glehniae 20 ~ 40 parts, Radix Ophiopogonis 10 ~ 20 parts, Fructus Schisandrae Chinensis 10 ~ 15 parts, the Radix Astragali 28 ~ 32 parts, Herba Agrimoniae 25 ~ 33 parts, Rhizoma Atractylodis 8 ~ 12 parts, 17 ~ 25 parts, Poria, Pumex 10 ~ 15 parts, Radix Salviae Miltiorrhizae 22 ~ 40 parts, Rhizoma Curcumae 9 ~ 15 parts, Rhizoma Sparganii 9 ~ 18 parts, 28 ~ 35 parts, the Radix Rehmanniae and 2 ~ 10 parts, Radix Glycyrrhizae, Radix Fissistigmatis Glaucescentis 20 ~ 45 parts, Radix Platycodonis 8 ~ 16 parts, Radix Ginseng 10 ~ 13 parts, 18 ~ 40 parts, Nidus Vespae, queen bee breast 9 ~ 15 parts, 3 ~ 9 parts, Bulbus Allii, Corm Eleocharitis 12 ~ 17 parts, Germinatus Phragmitis 3 ~ 9 parts, 9 ~ 17 parts, Fructus Citri Limoniae, Fructus Jujubae 3 ~ 9 parts, Scolopendra 7 ~ 18 parts, Gekko Swinhonis 12 ~ 19 parts, arsenicum 0.01 ~ 0.1 part, Radix Semiaquilegiae 12 ~ 18 parts, Herba Scutellariae Barbatae 18 ~ 35 parts, Radix Notoginseng 12 ~ 19 parts, Herba Selaginellae Doederleinii 13 ~ 19 parts, the Radix Astragali 20 ~ 26 parts, Pseudobulbus Cremastrae Seu Pleiones 11 ~ 16 parts, Folium Digitalis Lanatae 15 ~ 30 parts, Concha Ostreae 1 ~ 10 part, Spica Prunellae 2 ~ 9 parts, JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata) 8 ~ 17 parts, Radix Patriniae heterophyllae 20 ~ 22 parts, Rhizoma Paridis 12 ~ 17 parts, Herba Solani Lyrati 12 ~ 19 parts, saponin 12 ~ 24 parts, Herba Hedyotidis Diffusae 20 ~ 30 parts, Borneolum Syntheticum 8 ~ 12 parts, the Radix Angelicae Dahuricae 6 ~ 10 parts, Pheretima 5 ~ 10 parts, Radix Et Rhizoma Rhei 2 ~ 9 parts of Flos Carthami 3 ~ 10 parts, decoct with water and form.
Specific as follows:
Promote a preparation method for the medicine of nonsmall-cell lung cancer post-operative recovery, comprise drug decocting.
Described drug decocting step is:
(1) Radix Glehniae 20 ~ 40 parts, Radix Ophiopogonis 10 ~ 20 parts, Fructus Schisandrae Chinensis 10 ~ 15 parts, the Radix Astragali 28 ~ 32 parts, Herba Agrimoniae 25 ~ 33 parts, Rhizoma Atractylodis 8 ~ 12 parts, 17 ~ 25 parts, Poria, Pumex 10 ~ 15 parts, Radix Salviae Miltiorrhizae 22 ~ 40 parts, Rhizoma Curcumae 9 ~ 15 parts, Rhizoma Sparganii 9 ~ 18 parts, 28 ~ 35 parts, the Radix Rehmanniae and 2 ~ 10 parts, Radix Glycyrrhizae are put into baking oven;
Utilize applewood stove fire to toast, baking temperature keeps 80 ~ 125 DEG C, curing environment sealing, hypoxia, baking time 15 ~ 20 minutes;
Then the said medicine after baking all put into and decoct vessel, and put into the clear water of 3L, spacious lid utilizes intense fire to decoct to seething with excitement latter 10 minutes;
(2) cover decoction vessel cover, utilize slow fire to keep the intrinsic pressure power of decoction vessel to decoct 5 minutes higher than the pressure durations of normal atmosphere 1.3 ~ 1.5 times;
(3) in time decocting vessel inside residue 2L medicine soup, stop heating, pressure to be released, open wide and decoct vessel cover, medicine soup is separated with medicinal residues;
(4) Radix Fissistigmatis Glaucescentis 20 ~ 45 parts, Radix Platycodonis 8 ~ 16 parts, Radix Ginseng 10 ~ 13 parts, 18 ~ 40 parts, Nidus Vespae, queen bee breast 9 ~ 15 parts, 3 ~ 9 parts, Bulbus Allii, Corm Eleocharitis 12 ~ 17 parts, Germinatus Phragmitis 3 ~ 9 parts, 9 ~ 17 parts, Fructus Citri Limoniae, Fructus Jujubae 3 ~ 9 parts, Scolopendra 7 ~ 18 parts, Gekko Swinhonis 12 ~ 19 parts, arsenicum 0.01 ~ 0.1 part and Radix Semiaquilegiae 12 ~ 18 parts are put into frying pan and carry out slow fire bake and parch;
Described slow fire bake and parch process intermittent adds the vegetable oil that total amount is 8 ~ 12 parts;
The described vegetable oil added is Oleum Ricini, Oleum Helianthi and Testa oryzae oil, and the part by weight of Oleum Ricini, Oleum Helianthi and Testa oryzae oil is 1 ~ 2: 3 ~ 4: 4 ~ 6;
Continue bake and parch after 18 ~ 22 minutes, put into and decoct vessel, put into the 2L medicine soup that the clear water of 1L and step (3) are separated;
(5) cover decoction vessel cover, utilize slow fire to keep the intrinsic pressure power of decoction vessel to decoct 5 minutes higher than the pressure durations of normal atmosphere 1.3 ~ 1.5 times;
(6) in time decocting vessel inside residue 2L medicine soup, stop heating, pressure to be released, open wide and decoct vessel cover, medicine soup is separated with medicinal residues;
(7) Herba Scutellariae Barbatae 18 ~ 35 parts, Radix Notoginseng 12 ~ 19 parts, Herba Selaginellae Doederleinii 13 ~ 19 parts, the Radix Astragali 20 ~ 26 parts, Pseudobulbus Cremastrae Seu Pleiones 11 ~ 16 parts, Folium Digitalis Lanatae 15 ~ 30 parts, Concha Ostreae 1 ~ 10 part, Spica Prunellae 2 ~ 9 parts, JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata) 8 ~ 17 parts, Radix Patriniae heterophyllae 20 ~ 22 parts, Rhizoma Paridis 12 ~ 17 parts, Herba Solani Lyrati 12 ~ 19 parts, saponin 12 ~ 24 parts, Herba Hedyotidis Diffusae 20 ~ 30 parts, Borneolum Syntheticum 8 ~ 12 parts, the Radix Angelicae Dahuricae 6 ~ 10 parts, Pheretima 5 ~ 10 parts, Radix Et Rhizoma Rhei 2 ~ 9 parts of Flos Carthami 3 ~ 10 parts are put into blender, after Homogeneous phase mixing, be divided into by weight three parts stand-by;
Wherein: put into Oleum sesami for first part and fry, frying process is sealed high pressure, and frying oil temperature is 200 ~ 280 DEG C, and frying pressure is 75 ~ 82KPa, and frying time is 11 ~ 14 minutes;
Put into black soybean oil for second part to fry, frying process is sealed high pressure, and frying oil temperature is 200 ~ 280 DEG C, and frying pressure is 70 ~ 80KPa, and frying time is 12 ~ 15 minutes;
Put into Oleum Arachidis hypogaeae semen and fry for 3rd part, frying process is sealed high pressure, and frying oil temperature is 200 ~ 280 DEG C, and frying pressure is 78 ~ 86KPa, and frying time is 10 ~ 13 minutes;
Medicine after finally fried by three parts is pulled out and drains, respectively three parts of drug utilization steel are worn into 600 object powder, and by powder mix homogeneously, all put into and decoct vessel, and add the 2L medicine soup separated in the clear water of 1L and step (6) and be uniformly mixed;
(8) spacious lid utilizes intense fire to decoct to seething with excitement latter 10 minutes, and stop heating, the soup upper strata medicinal liquid 0.5 ~ 0.8L that gets it filled gives over to for subsequent use;
(9) cover decoction vessel cover, utilize slow fire to keep the intrinsic pressure power of decoction vessel to decoct 5 minutes higher than the pressure durations of normal atmosphere 1.3 ~ 1.5 times;
(10) in time decocting vessel inside residue 1L medicine soup, stop heating, pressure to be released, open wide and decoct vessel cover, medicine soup is separated with medicinal residues.
A kind ofly promote that the using method of the medicine of nonsmall-cell lung cancer post-operative recovery is as follows:
(1) get it filled in drug decocting step (8) soup upper strata medicinal liquid 0.5 ~ 0.8L, that this medicine soup is cooled to room temperature, load spray bottle, and in spray bottle, add 0.1L Mel, after mix homogeneously, can directly spray in oral cavity, each fountain height is not more than 0.05L, within every 20 ~ 30 minutes, sprays once;
(2), when in drug decocting step (10), isolated medicine soup is cooled to 30 ~ 50 DEG C, a point morning and evening takes for twice, each 0.5L;
(3) all same gunnysack bag is loaded by after isolated medicinal residues mix homogeneously in drug decocting step (3), (6) and (10), for the external hot compress of thoracic pulmonary when medicinal residues temperature is at 40 ~ 60 DEG C, the hot compress time is forward and backward 30 minutes of medication in morning, forward and backward 30 minutes of medication in evening, one day four times, each 10 ~ 15 minutes.
The present invention boils according to the medicine of the promotion nonsmall-cell lung cancer post-operative recovery described in embodiment 1,2, preparation method, and the use in later stage is carried out according to respective using method, patient was all selected from the age between 45 ~ 60 years old, 60 nonsmall-cell lung cancer post-operative recovery persons that self-recovery ability is stronger, wherein in embodiment 1 30, in embodiment 2 30, after taking medicine, average case carries out data compilation, and concrete condition is as shown in table 1:
Table 1:
As seen from the above table, embodiment 1,2 is all to promoting the effect that nonsmall-cell lung cancer post-operative recovery is certain, but, but there is certain difference in the degree that takes effect over the course for the treatment of, through the recovery follow-up investigation to 60 patients, and the data of patient's feedback in recovery process are arranged, and to data analysis, think that embodiment 2 is technical schemes of a kind of optimum.
In the above-described embodiments, preferred forms of the present invention is described, obviously, under inventive concept of the present invention, still can make a lot of change.At this, should illustrate, any change made under inventive concept of the present invention all will fall within the scope of protection of the present invention.

Claims (10)

1. one kind promotes the medicine of nonsmall-cell lung cancer post-operative recovery, it is characterized in that: calculate by weight, comprise: Radix Glehniae 20 ~ 40 parts, Radix Ophiopogonis 10 ~ 20 parts, Fructus Schisandrae Chinensis 10 ~ 15 parts, the Radix Astragali 28 ~ 32 parts, Herba Agrimoniae 25 ~ 33 parts, Rhizoma Atractylodis 8 ~ 12 parts, 17 ~ 25 parts, Poria, Pumex 10 ~ 15 parts, Radix Salviae Miltiorrhizae 22 ~ 40 parts, Rhizoma Curcumae 9 ~ 15 parts, Rhizoma Sparganii 9 ~ 18 parts, 28 ~ 35 parts, the Radix Rehmanniae and 2 ~ 10 parts, Radix Glycyrrhizae, decoct with water and form.
2. the medicine of promotion nonsmall-cell lung cancer post-operative recovery according to claim 1, it is characterized in that: calculate by weight, also comprise: Radix Fissistigmatis Glaucescentis 20 ~ 45 parts, Radix Platycodonis 8 ~ 16 parts, Radix Ginseng 10 ~ 13 parts, 18 ~ 40 parts, Nidus Vespae, queen bee breast 9 ~ 15 parts, 3 ~ 9 parts, Bulbus Allii, Corm Eleocharitis 12 ~ 17 parts, Germinatus Phragmitis 3 ~ 9 parts, 9 ~ 17 parts, Fructus Citri Limoniae, Fructus Jujubae 3 ~ 9 parts, Scolopendra 7 ~ 18 parts, Gekko Swinhonis 12 ~ 19 parts, arsenicum 0.01 ~ 0.1 part, Radix Semiaquilegiae 12 ~ 18 parts, Herba Scutellariae Barbatae 18 ~ 35 parts, Radix Notoginseng 12 ~ 19 parts, Herba Selaginellae Doederleinii 13 ~ 19 parts, the Radix Astragali 20 ~ 26 parts, Pseudobulbus Cremastrae Seu Pleiones 11 ~ 16 parts, Folium Digitalis Lanatae 15 ~ 30 parts, Concha Ostreae 1 ~ 10 part, Spica Prunellae 2 ~ 9 parts, JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata) 8 ~ 17 parts, Radix Patriniae heterophyllae 20 ~ 22 parts, Rhizoma Paridis 12 ~ 17 parts, Herba Solani Lyrati 12 ~ 19 parts, saponin 12 ~ 24 parts, Herba Hedyotidis Diffusae 20 ~ 30 parts, Borneolum Syntheticum 8 ~ 12 parts, the Radix Angelicae Dahuricae 6 ~ 10 parts, Pheretima 5 ~ 10 parts, Radix Et Rhizoma Rhei 2 ~ 9 parts of Flos Carthami 3 ~ 10 parts.
3. the medicine of promotion nonsmall-cell lung cancer post-operative recovery according to claim 1, it is characterized in that: calculate by weight, comprise: Radix Glehniae 30 parts, Radix Ophiopogonis 15 parts, Fructus Schisandrae Chinensis 12 parts, the Radix Astragali 30 parts, Herba Agrimoniae 30 parts, Rhizoma Atractylodis 9 parts, 20 parts, Poria, Pumex 12 parts, Radix Salviae Miltiorrhizae 30 parts, Rhizoma Curcumae 12 parts, Rhizoma Sparganii 12 parts, 30 parts, the Radix Rehmanniae, 6 parts, Radix Glycyrrhizae, Radix Fissistigmatis Glaucescentis 30 parts, Radix Platycodonis 10 parts, Radix Ginseng 12 parts, 28 parts, Nidus Vespae, queen bee breast 11 parts, 5 parts, Bulbus Allii, Corm Eleocharitis 16 parts, Germinatus Phragmitis 5 parts, 15 parts, Fructus Citri Limoniae, Fructus Jujubae 6 parts, Scolopendra 10 parts, Gekko Swinhonis 15 parts, arsenicum 0.05 part, Radix Semiaquilegiae 13 parts, Herba Scutellariae Barbatae 22 parts, Radix Notoginseng 15 parts, Herba Selaginellae Doederleinii 17 parts, the Radix Astragali 24 parts, Pseudobulbus Cremastrae Seu Pleiones 13 parts, Folium Digitalis Lanatae 28 parts, Concha Ostreae 6 parts, Spica Prunellae 4 parts, JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata) 15 parts, Radix Patriniae heterophyllae 21 parts, Rhizoma Paridis 15 parts, Herba Solani Lyrati 16 parts, saponin 18 parts, Herba Hedyotidis Diffusae 25 parts, Borneolum Syntheticum 10 parts, the Radix Angelicae Dahuricae 8 parts, Pheretima 6 parts, Radix Et Rhizoma Rhei 4 parts, 7 parts, Flos Carthami, decoct with water and form.
4. promote a preparation method for the medicine of nonsmall-cell lung cancer post-operative recovery, it is characterized in that: comprise drug decocting.
5. the preparation method of the medicine of promotion nonsmall-cell lung cancer post-operative recovery according to claim 4, is characterized in that: described drug decocting step is:
(1) Radix Glehniae 20 ~ 40 parts, Radix Ophiopogonis 10 ~ 20 parts, Fructus Schisandrae Chinensis 10 ~ 15 parts, the Radix Astragali 28 ~ 32 parts, Herba Agrimoniae 25 ~ 33 parts, Rhizoma Atractylodis 8 ~ 12 parts, 17 ~ 25 parts, Poria, Pumex 10 ~ 15 parts, Radix Salviae Miltiorrhizae 22 ~ 40 parts, Rhizoma Curcumae 9 ~ 15 parts, Rhizoma Sparganii 9 ~ 18 parts, 28 ~ 35 parts, the Radix Rehmanniae and 2 ~ 10 parts, Radix Glycyrrhizae are put into decoction vessel, and put into the clear water of 3L, spacious lid utilizes intense fire to decoct to seething with excitement latter 10 minutes;
(2) cover decoction vessel cover, utilize slow fire to keep the intrinsic pressure power of decoction vessel to decoct 5 minutes higher than the pressure durations of normal atmosphere 1.3 ~ 1.5 times;
(3) in time decocting vessel inside residue 1L medicine soup, stop heating, pressure to be released, open wide and decoct vessel cover, medicine soup is separated with medicinal residues.
6. the preparation method of the medicine of promotion nonsmall-cell lung cancer post-operative recovery according to claim 4, is characterized in that: described drug decocting step is:
(1) Radix Glehniae 20 ~ 40 parts, Radix Ophiopogonis 10 ~ 20 parts, Fructus Schisandrae Chinensis 10 ~ 15 parts, the Radix Astragali 28 ~ 32 parts, Herba Agrimoniae 25 ~ 33 parts, Rhizoma Atractylodis 8 ~ 12 parts, 17 ~ 25 parts, Poria, Pumex 10 ~ 15 parts, Radix Salviae Miltiorrhizae 22 ~ 40 parts, Rhizoma Curcumae 9 ~ 15 parts, Rhizoma Sparganii 9 ~ 18 parts, 28 ~ 35 parts, the Radix Rehmanniae and 2 ~ 10 parts, Radix Glycyrrhizae are put into baking oven;
Utilize applewood stove fire to toast, baking temperature keeps 80 ~ 125 DEG C, curing environment sealing, hypoxia, baking time 15 ~ 20 minutes;
Then the said medicine after baking all put into and decoct vessel, and put into the clear water of 3L, spacious lid utilizes intense fire to decoct to seething with excitement latter 10 minutes;
(2) cover decoction vessel cover, utilize slow fire to keep the intrinsic pressure power of decoction vessel to decoct 5 minutes higher than the pressure durations of normal atmosphere 1.3 ~ 1.5 times;
(3) in time decocting vessel inside residue 2L medicine soup, stop heating, pressure to be released, open wide and decoct vessel cover, medicine soup is separated with medicinal residues;
(4) Radix Fissistigmatis Glaucescentis 20 ~ 45 parts, Radix Platycodonis 8 ~ 16 parts, Radix Ginseng 10 ~ 13 parts, 18 ~ 40 parts, Nidus Vespae, queen bee breast 9 ~ 15 parts, 3 ~ 9 parts, Bulbus Allii, Corm Eleocharitis 12 ~ 17 parts, Germinatus Phragmitis 3 ~ 9 parts, 9 ~ 17 parts, Fructus Citri Limoniae, Fructus Jujubae 3 ~ 9 parts, Scolopendra 7 ~ 18 parts, Gekko Swinhonis 12 ~ 19 parts, arsenicum 0.01 ~ 0.1 part and Radix Semiaquilegiae 12 ~ 18 parts are put into frying pan and carry out slow fire bake and parch;
Described slow fire bake and parch process intermittent adds the vegetable oil that total amount is 8 ~ 12 parts;
The described vegetable oil added is Oleum Ricini, Oleum Helianthi and Testa oryzae oil, and the part by weight of Oleum Ricini, Oleum Helianthi and Testa oryzae oil is 1 ~ 2: 3 ~ 4: 4 ~ 6;
Continue bake and parch after 18 ~ 22 minutes, put into and decoct vessel, put into the 2L medicine soup that the clear water of 1L and step (3) are separated;
(5) cover decoction vessel cover, utilize slow fire to keep the intrinsic pressure power of decoction vessel to decoct 5 minutes higher than the pressure durations of normal atmosphere 1.3 ~ 1.5 times;
(6) in time decocting vessel inside residue 2L medicine soup, stop heating, pressure to be released, open wide and decoct vessel cover, medicine soup is separated with medicinal residues;
(7) Herba Scutellariae Barbatae 18 ~ 35 parts, Radix Notoginseng 12 ~ 19 parts, Herba Selaginellae Doederleinii 13 ~ 19 parts, the Radix Astragali 20 ~ 26 parts, Pseudobulbus Cremastrae Seu Pleiones 11 ~ 16 parts, Folium Digitalis Lanatae 15 ~ 30 parts, Concha Ostreae 1 ~ 10 part, Spica Prunellae 2 ~ 9 parts, JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata) 8 ~ 17 parts, Radix Patriniae heterophyllae 20 ~ 22 parts, Rhizoma Paridis 12 ~ 17 parts, Herba Solani Lyrati 12 ~ 19 parts, saponin 12 ~ 24 parts, Herba Hedyotidis Diffusae 20 ~ 30 parts, Borneolum Syntheticum 8 ~ 12 parts, the Radix Angelicae Dahuricae 6 ~ 10 parts, Pheretima 5 ~ 10 parts, Radix Et Rhizoma Rhei 2 ~ 9 parts of Flos Carthami 3 ~ 10 parts are put into blender, after Homogeneous phase mixing, be divided into by weight three parts stand-by;
Wherein: put into Oleum sesami for first part and fry, frying process is sealed high pressure, and frying oil temperature is 200 ~ 280 DEG C, and frying pressure is 75 ~ 82KPa, and frying time is 11 ~ 14 minutes;
Put into black soybean oil for second part to fry, frying process is sealed high pressure, and frying oil temperature is 200 ~ 280 DEG C, and frying pressure is 70 ~ 80KPa, and frying time is 12 ~ 15 minutes;
Put into Oleum Arachidis hypogaeae semen and fry for 3rd part, frying process is sealed high pressure, and frying oil temperature is 200 ~ 280 DEG C, and frying pressure is 78 ~ 86KPa, and frying time is 10 ~ 13 minutes;
Medicine after finally fried by three parts is pulled out and drains, respectively three parts of drug utilization steel are worn into 600 object powder, and by powder mix homogeneously, all put into and decoct vessel, and add the 2L medicine soup separated in the clear water of 1L and step (6) and be uniformly mixed;
(8) spacious lid utilizes intense fire to decoct to seething with excitement latter 10 minutes, and stop heating, the soup upper strata medicinal liquid 0.5 ~ 0.8L that gets it filled gives over to for subsequent use;
(9) cover decoction vessel cover, utilize slow fire to keep the intrinsic pressure power of decoction vessel to decoct 5 minutes higher than the pressure durations of normal atmosphere 1.3 ~ 1.5 times;
(10) in time decocting vessel inside residue 1L medicine soup, stop heating, pressure to be released, open wide and decoct vessel cover, medicine soup is separated with medicinal residues.
7. the preparation method of the medicine of promotion nonsmall-cell lung cancer post-operative recovery according to claim 5, it is characterized in that: a kind ofly promote that the using method of the medicine of nonsmall-cell lung cancer post-operative recovery is as follows: when medicine soup is cooled to 30 ~ 50 DEG C, divide and sooner or later take for twice, each 0.5L.
8. the preparation method of the medicine of promotion nonsmall-cell lung cancer post-operative recovery according to claim 6, is characterized in that: a kind ofly promote that the using method of the medicine of nonsmall-cell lung cancer post-operative recovery is as follows:
(1) get it filled in drug decocting step (8) soup upper strata medicinal liquid 0.5 ~ 0.8L, that this medicine soup is cooled to room temperature, load spray bottle, and in spray bottle, add 0.1L Mel, after mix homogeneously, can directly spray in oral cavity, each fountain height is not more than 0.05L, within every 20 ~ 30 minutes, sprays once;
(2), when in drug decocting step (10), isolated medicine soup is cooled to 30 ~ 50 DEG C, a point morning and evening takes for twice, each 0.5L;
(3) all same gunnysack bag is loaded by after isolated medicinal residues mix homogeneously in drug decocting step (3), (6) and (10), for the external hot compress of thoracic pulmonary when medicinal residues temperature is at 40 ~ 60 DEG C, the hot compress time is forward and backward 30 minutes of medication in morning, forward and backward 30 minutes of medication in evening, one day four times, each 10 ~ 15 minutes.
9. the using method of the medicine of promotion nonsmall-cell lung cancer post-operative recovery according to claim 8, is characterized in that: after taking medicine three days, pulse frequency is 85 ~ 105 beats/min, respiratory frequency is 20-22 beat/min, cough and expectoration amount is 10-20ml/ day, Hb numerical value 100-120g/L, leukocyte count are 12-16 × 10 9/ L.
10. the using method of the medicine of promotion nonsmall-cell lung cancer post-operative recovery according to claim 9, is characterized in that: taking medicine, pulse frequency after a week is 80-100 beat/min, respiratory frequency is 18-20 beat/min, cough and expectoration amount is 0-8ml/ day, Hb numerical value 110-130g/L, leukocyte count are 4-10 × 10 9/ L.
CN201510648893.5A 2015-10-08 2015-10-08 Medicine for promoting NSCLC (non-small-cell lung cancer) postoperative recovery, preparation method and application method Pending CN105169270A (en)

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