CN105168944A - Traditional Chinese medicinal composition for treating breast cancer and application thereof - Google Patents

Traditional Chinese medicinal composition for treating breast cancer and application thereof Download PDF

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Publication number
CN105168944A
CN105168944A CN201510686245.9A CN201510686245A CN105168944A CN 105168944 A CN105168944 A CN 105168944A CN 201510686245 A CN201510686245 A CN 201510686245A CN 105168944 A CN105168944 A CN 105168944A
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parts
radix
herba
fructus
chinese medicine
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王传秀
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Qingdao Yuntian Biotechnology Co Ltd
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Qingdao Yuntian Biotechnology Co Ltd
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Abstract

The invention relates to a traditional Chinese medicinal composition for treating breast cancer and an application thereof. The traditional Chinese medicinal composition for treating the breast cancer comprises the following components in parts by weight: 10-60 parts of ginseng, 10-30 parts of astragalus, 20-35 parts of edible tulip, 4-10 parts of scorpio, 8-12 parts of trogopterus dung, 5-20 parts of costus root, 5-15 parts of sculellaria barbata, 10-30 parts of oldenlandia diffusa, 10-20 parts of golden silkworm, 6-10 parts of bighead atractylodes rhizome, 4-10 parts of Chinese rhubarb, 15-30 parts of cortex phellodendri, 5-15 parts of fructus lycii, 5-20 parts of glossy privet fruit, 5-20 parts of dandelion, 5-25 parts of radix pseudostellariae, 15-18 parts of fritillaria cirrhosa, 10-30 parts of selfheal, 5-17 parts of cynomorium songaricum, 7-23 parts of fructus forsythiae, 5-16 parts of fructus aurantii immaturus, 4-10 parts of pangolin scales, 15-30 parts of cowherb seeds and 5-16 parts of aloe. The traditional Chinese medicinal composition for treating the breast cancer is scientifically prepared and has obvious effects of activating blood and removing stasis, strengthening body resistance to dispel pathogenic factors, repairing and improving an immune system, inhibiting division of cancer cells, discharging out necrosis cells and restoring and improving physique of a patient, so that no operation or chemotherapy needs to be carried out on the breast cancer, curative ratio is more than 99%, repetition rate is less than 2%, and the patient is avoided from pain in operation and chemotherapy; besides, capsules are easy in operation, so that the traditional Chinese medicinal composition for treating the breast cancer is applicable to large-scale industrial production.

Description

A kind of Chinese medicine composition for the treatment of breast carcinoma and uses thereof
Technical field
The invention belongs to breast cancer treatment field, particularly relate to a kind of Chinese medicine composition for the treatment of breast carcinoma and uses thereof.
Background technology
Breast carcinoma is definitely society women " the second killer ", and the sickness rate of breast carcinoma is only second to cervical cancer in China, and crowd's morbidity is 23/,100,000; Account for the 7-10% of the various malignant tumor of whole body, so breast carcinoma has become the great public health problem of current social.Early stage mastocarcinoma patient is without any discomfort, and in breast, only have the lump that smaller, not bitterly, nipple is also unchanged; Breast carcinoma is developed to late period, and surface skin is invaded, and can occur callosity, and notably skin ulceration forms ulcer.The cause of disease of breast carcinoma does not still understand, how front relevant with postmenopausal estrogen with menopause after deliberation, another inherited genetic factors, dietary factor and some breast benign disease and breast carcinoma have certain relation.
At present, western medical treatment breast carcinoma mainly adopts hands art, radiotherapy, the methods such as chemotherapy, but the equal defectiveness of these methods, one is only have early stage patient just can carry out operative treatment, although mammary gland is not the important organ of human life activity, healing can be reached by surgical resection, but because mammary glandular cell just loses Normocellular characteristic after undergoing mutation, organizational structure is disorderly, cell connects loose, cancerous cell is easy to come off free, whole body is sent out with blood or lymph fluid etc., form early stage far-end transfer, very large difficulty is added to the clinical cure of breast carcinoma, two is that radiation and chemotherapy can only the misery of respite patient, thoroughly can not eradicate disease, have obvious limitation, three be patient after excision, radiation and chemotherapy, easily cause sequela, the injury of operative treatment to patient body and soul is all huge in addition, has a strong impact on quality of life of patients.In recent years, China's Chinese medicine creates very large progress in treatment breast carcinoma, occurred diversified medicine, but effect is all undesirable.The present invention, by above-mentioned all medicine compatibilities, has circulation of qi promoting and blood, dissolves the stasis of blood stagnant, and detumescence is driven pain, played softening the hard mass to cure cancer.
The Drug therapy of existing market still with excision, Western medicine, chemotherapy, radiotherapy for Main Means, although Chinese medicine preparation also has much, effective effect can be played little.
Summary of the invention:
For the defect of prior art, the present invention be directed to the present situation of current Therapeutic cancer, provide that one need not be excised, chemotherapy, just can reach the Chinese medicine composition of therapeutic effect, and have no side effect, effective.Specifically, the present invention realizes like this.
First, inventor expects the large mistake of the vigour of patient with breast cancer, does not think appetite, spirit depressing, hypoimmunity, lean body mass, and therefore inventor reaches raising body immunity, facilitating digestion, invigorating the spleen to benefit the lung, the object of promoting the production of body fluid and inducing sedation of the mind with Radix Ginseng, Radix Pseudostellariae for monarch drug; Further, inventor considers and will remove tumor, repair body, excreted by histiocyte downright bad in body, inventor filters out Fructus Forsythiae, Herba Scutellariae Barbatae, Herba Hedyotidis Diffusae etc. and dominates outside tumor lead body for ministerial drug from numerous Chinese medicine, and Fructus Aurantii Immaturus, Radix Aucklandiae (Radix Vladimiriae) etc. make ministerial drug arrival lesions position play a role for making medicine, Pseudobulbus Cremastrae Seu Pleiones, Fructus Ligustri Lucidi etc. are condiment, assist a ruler in governing a country ministerial drug eliminating evil, and promote monarch drug curative effect, reach the object removing tumor, healthy energy internal memory.Above drug matching strongly invigorating primordial QI, improve immunity, anticancer, toxin expelling of invigorating blood circulation, except tumor eliminating carbuncle, physique is strengthened in bone and muscle strengthening.
Then, inventor provides a kind of prescriptions of Chinese medicine for the treatment of breast carcinoma according to drug matching experience, each raw material dosage of prescription all has good curative effect in weight portion scope of the present invention, described formula and weight portion are: Radix Ginseng 10-60 part, Radix Astragali 10-30 part, Pseudobulbus Cremastrae Seu Pleiones 20-35 part, Scorpio 4-10 part, Oletum Trogopterori 8-12 part, Radix Aucklandiae (Radix Vladimiriae) 5-20 part, Herba Scutellariae Barbatae 5-15 part, Herba Hedyotidis Diffusae 10-30 part, gold silkworm 10-20 part, Rhizoma Atractylodis Macrocephalae 6-10 part, Radix Et Rhizoma Rhei 4-10 part, Cortex Phellodendri 15-30 part, Fructus Lycii 5-15 part, Fructus Ligustri Lucidi 5-20 part, Herba Taraxaci 5-20 part, Radix Pseudostellariae 5-25 part, Bulbus Fritillariae Cirrhosae 15-18 part, Spica Prunellae 10-30 part, Herba Cynomorii 5-17 part, Fructus Forsythiae 7-23 part, Fructus Aurantii Immaturus 5-16 part, Squama Manis 4-10 part, Semen Vaccariae 15-30 part, Aloe 5-16 part.
Carry out preferably to the formula of above-mentioned weight portion, reach better technique effect, preferred formula is: Radix Ginseng 20-50 part, Radix Astragali 15-25 part, Pseudobulbus Cremastrae Seu Pleiones 25-30 part, Scorpio 6-10 part, Oletum Trogopterori 10-12 part, Radix Aucklandiae (Radix Vladimiriae) 10-15 part, Herba Scutellariae Barbatae 10-15 part, Herba Hedyotidis Diffusae 15-25 part, gold silkworm 15-20 part, Rhizoma Atractylodis Macrocephalae 8-10 part, Radix Et Rhizoma Rhei 6-8 part, Cortex Phellodendri 20-25 part, Fructus Lycii 10-15 part, Fructus Ligustri Lucidi 15-20 part, Herba Taraxaci 15-20 part, Radix Pseudostellariae 15-20 part, Bulbus Fritillariae Cirrhosae 15-18 part, Spica Prunellae 15-25 part, Herba Cynomorii 10-12 part, Fructus Forsythiae 10-17 part, Fructus Aurantii Immaturus 8-12 part, Squama Manis 8-10 part, Semen Vaccariae 20-30 part, Aloe 9-13 part.
Carry out preferably to the formula of above-mentioned weight portion, reach better technique effect, most preferred formula is: Radix Ginseng 35 parts, the Radix Astragali 20 parts, Pseudobulbus Cremastrae Seu Pleiones 27 parts, Scorpio 9 parts, Oletum Trogopterori 10 parts, Radix Aucklandiae (Radix Vladimiriae) 10 parts, Herba Scutellariae Barbatae 15 parts, Herba Hedyotidis Diffusae 20 parts, golden silkworm 20 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, Radix Et Rhizoma Rhei 7 parts, Cortex Phellodendri 25 parts, Fructus Lycii 12 parts, Fructus Ligustri Lucidi 18 parts, Herba Taraxaci 20 parts, Radix Pseudostellariae 15 parts, Bulbus Fritillariae Cirrhosae 18 parts, Spica Prunellae 25 parts, Herba Cynomorii 10 parts, Fructus Forsythiae 13 parts, Fructus Aurantii Immaturus 11 parts, Squama Manis 9 parts, Semen Vaccariae 25 parts, Aloe 10 parts.
The function of each taste Chinese crude drug used in the Chinese medicine composition for the treatment of breast carcinoma of the present invention is as follows:
Radix Ginseng: sweet in the mouth, property is put down.
Gui Jing: return spleen, lung, heart channel.
Function cures mainly: strongly invigorating primordial QI, and multiple arteries and veins takes off admittedly, invigorating the spleen to benefit the lung, promoting the production of body fluid and inducing sedation of the mind, and for weak body and prostration, cold extremities faint pulse, insufficiency of the spleen lack of appetite, the deficiency of the lung is breathed with cough, and Tianjin wound is thirsty, and interior-heat is quenched one's thirst, prolonged illness weakness with emaciation.
The Radix Astragali: sweet in the mouth, warm in nature.
Gui Jing: return lung, spleen channel.
Function cures mainly: invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation, weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle difficulty is burst, burst for a long time and do not hold back, blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst, and is the composition being commonly used to treat various cancer clinically.
Pseudobulbus Cremastrae Seu Pleiones: sweet in the mouth, cool in nature.
Gui Jing: return liver, spleen channel.
Function cures mainly: heat-clearing and toxic substances removing, dissipating phlegm and resolving masses, for carbuncle furunculosis, and scrofula sucutaneous nodule, tuberculous lymphadenitis, snake bite and insect sting.
Scorpio: acrid in the mouth, poisonous.
Gui Jing: return Liver Channel.
Function cures mainly: endogenous wind stopping spasmolytic, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain, and for infantile convulsion, tic spasm, middle air port is askew, hemiplegia, migraine and general headache, skin infection, scrofula.
Oletum Trogopterori: sweet in the mouth, warm in nature.
Function cures mainly: promoting blood circulation to remove blood stasis, parch to black stop blooding, have a pain for trusted subordinate's congestion, dysmenorrhea, blood stasis amenorrhea, puerperal abdominalgia with blood stasis; Parch to black controls metrostaxis; Traumatic injury is controlled in external.
Radix Aucklandiae (Radix Vladimiriae): sweet in the mouth, warm in nature.
Gui Jing: return spleen, stomach, large intestine, gallbladder meridian.
Function cures mainly: can lead to manner, easing stomach-QI, row irritability, loose stagnant gas, and broken stagnation of QI is only distressed, and by cold air, peace cholera is vomited and diarrhoea, and vomiting regurgitation of food from the stomach, except painful abdominal mass addiction disease block, umbilicus abdominal distention and pain, antiabortive loose poison, controls dysentery required, and wards off pestilential pathogen miasma.
Herba Scutellariae Barbatae: acrid in the mouth, cold in nature.
Gui Jing: return lung, liver, kidney channel.
Function cures mainly: heat-clearing and toxic substances removing, blood stasis dispelling diuresis, and for furuncle swelling toxin, laryngopharynx swelling and pain, venom, falls and flutter the pain of injury, edema.
Herba Hedyotidis Diffusae: sweet in the mouth, cool in nature.
Gui Jing: enter stomach, large intestine, small intestine meridian.
Function cures mainly: heat-clearing and toxic substances removing, inducing diuresis to remove edema, promoting blood circulation and stopping pain.For acute appendicitis (appendicitis), furuncle toxic swelling, jaundice due to damp-heat, the diseases such as dysuria; Furuncle carbuncle is controlled in external, venom.
Gold silkworm: sweet in the mouth, property is put down.
Gui Jing: return liver,spleen,kidney warp.
Function cures mainly: clearing away heat and cooling blood, removing dampness and detoxicating.For hemoptysis of pulmonary tuberculosis, diabetes, nephritis, cystitis, myasthenia gravis, rheumatic and rheumatoid arthritis, venom.
The Rhizoma Atractylodis Macrocephalae: bitter in the mouth, warm in nature.
Gui Jing: return spleen, stomach warp.
Function cures mainly: invigorating the spleen and benefiting QI, dampness diuretic, and for insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.
Radix Et Rhizoma Rhei: bitter in the mouth, cold in nature.
Gui Jing: return spleen, stomach, large intestine, liver, pericardium channel.
Function cures mainly: purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation.For excess-heat constipation, stagnant stomachache, dysentery is not well, jaundice due to damp-heat, and heat in blood tells nosebleed, conjunctival congestion, pharyngeal swelling, abdominalgia with intestinal abscess, carbuncle furuncle, blood stasis amenorrhea, traumatic injury, external treatment burn due to hot liquid or fire; Upper gastrointestinal hemorrhage.Radix et Rhizoma Rhei (stir-fried with wine) is apt to clear part of the body cavity above the diaphragm housing the heart and lungs noxious heat in the blood system.For conjunctival congestion pharyngeal swelling, gingivitis.Radix Et Rhizoma Rhei rushes down exerts oneself to delay, eliminating fire and detoxication.For pathogenic fire,toxin and furuncles.Charred Radix Et Rhizoma Rhei cooling blood and removing stasis stops blooding.Stasis of blood hemorrhage is had for heat in blood.
Cortex Phellodendri: bitter in the mouth, cold in nature.
Gui Jing: return kidney, urinary bladder channel.
Function cures mainly: heat clearing and damp drying, and pathogenic fire purging removes steams, detoxification sore treatment, sore swollen toxin, eczema pruritus, for hyperactivity of fire caused by deficiency of YIN, and night sweat hectic fever due to YIN-deficiency.
Fructus Lycii: sweet in the mouth, property is put down.
Gui Jing: return liver, kidney channel.
Function cures mainly: nourishing the liver and kidney, replenishing vital essence to improve eyesight.For asthenia damage of essence, soreness of waist and knee joint, vertigo and tinnitus, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, and blurred vision is failed to understand.
Fructus Ligustri Lucidi: sweet in the mouth, cool in nature.
Gui Jing: return liver, kidney channel.
Function cures mainly: nourishing the liver and kidney, improving eyesight black hair.For vertigo and tinnitus, soreness of the waist and knees, early whitening of beard and hair, poor vision.
Herba Taraxaci: bitter in the mouth, cold in nature.
Gui Jing: return liver, stomach warp.
Function cures mainly: heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, inducing diuresis for treating stranguria syndrome.For furuncle swelling toxin, acute mastitis, scrofula, conjunctival congestion, pharyngalgia, lung abscess, acute appendicitis, jaundice due to damp-heat, the puckery pain of pyretic stranguria.
Radix Pseudostellariae: sweet in the mouth, property is put down.
Gui Jing: return spleen, lung meridian.
Function cures mainly: replenishing QI to invigorate the spleen, promoting the production of body fluid for nourishing the lung, tired for insufficiency of the spleen body, inappetence, and weak after being ill, deficiency of both vital energy and Yin, spontaneous perspiration is thirsty, dryness of the lung dry cough.
Bulbus Fritillariae Cirrhosae: bitter in the mouth, cold in nature.
Gui Jing: return lung, heart channel.
Function cures mainly: clearing heat and moistening lung, preventing phlegm from forming and stopping coughing, for lung-heat type cough, and the few expectorant of dry cough, deficiency of YIN chronic cough, sputum with blood
Spica Prunellae: acrid in the mouth, cold in nature.
Gui Jing: return liver, gallbladder meridian.
Function cures mainly: relieve inflammation or internal heat, improving eyesight, eliminating stagnation, detumescence.For conjunctival congestion and swelling pain, order pearl nyctalgia, has a headache dizzy, scrofula, goiter, and acute mastitis swells and ache; Thyromegaly, tuberculous lymphadenitis, cyclomastopathy.
Herba Cynomorii: sweet in the mouth, warm in nature.
Gui Jing: return spleen, kidney, large intestine channel.
Function cures mainly: kidney-replenishing, benefiting essence-blood, loosening bowel to relieve constipation.Soft for waist knee joint flaccidity, sexual impotence spermatorrhea, dryness of the intestine constipation.
Fructus Forsythiae: bitter in the mouth, is slightly cold.
Gui Jing: return lung, the heart, small intestine meridian.
Function cures mainly: heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.For carbuncle, scrofula, acute mastitis, erysipelas, anemopyretic cold, epidemic febrile disease from the beginning of, warmly join the army, high hot excessive thirst, coma sends out speckle, pyretic stranguria urine retention.
Fructus Aurantii Immaturus: bitter in the mouth, warm in nature.
Gui Jing: return spleen, stomach warp.
Function cures mainly: dispelling the stagnated QI removing food stagnancy, loose painful abdominal mass of reducing phlegm.Stop in stagnant, feeling of fullness distending pain, heavy after dysentery, constipation, the stagnant vapour lock thoracic obstruction of expectorant.
Squama Manis: salty in the mouth, cold in nature,
Gui Jing: return Liver Channel, stomach warp.
Function cures mainly: can blood circulation promoting and dispersing pathogen accumulation, stimulating milk secretion of stimulating the menstrual flow, the routed heavily fortified point of eliminating carbuncle.Main blood stasis amenorrhea, lump in the abdomen, rheumatic arthralgia, agalactia, carbuncle, scrofula etc.
Semen Vaccariae: bitter in the mouth, property is put down.
Gui Jing: return liver, stomach warp.
Function cures mainly: promoting blood circulation to restore menstrual flow, and stimulating milk secretion is subsided a swelling.For agalactia, amenorrhea, dysmenorrhea, acute mastitis swells and ache
Aloe: bitter in the mouth, cold in nature.
Gui Jing: return liver, stomach, large intestine channel.
Function cures mainly: the dizziness of Liver Channel excess-heat, headache, tinnitus, agitation, constipation, pediatric epilepsy scared, infantile malnutrition, catharsis and toxin expelling.
The present invention is to above prescription through conscientious research, and according to the reasonability of middle medical drugs, invention proposes concrete a kind of preparation method for the treatment of the Chinese medicine composition of breast carcinoma, and concrete steps are for I;
1) Radix Ginseng, Radix Pseudostellariae, the Radix Astragali are broken into fine powder and cross 60 mesh sieves, for subsequent use;
2) by Pseudobulbus Cremastrae Seu Pleiones, Radix Aucklandiae (Radix Vladimiriae), Herba Scutellariae Barbatae, Herba Hedyotidis Diffusae, the Rhizoma Atractylodis Macrocephalae, Scorpio, Oletum Trogopterori, Radix Et Rhizoma Rhei, Fructus Forsythiae, golden silkworm, Cortex Phellodendri, Fructus Lycii, Fructus Ligustri Lucidi, Herba Taraxaci, Radix Pseudostellariae, Bulbus Fritillariae Cirrhosae, Spica Prunellae, Herba Cynomorii, Fructus Aurantii Immaturus, Squama Manis, Semen Vaccariae, Aloe remove impurity, for subsequent use;
3) by Scorpio, Oletum Trogopterori, Radix Et Rhizoma Rhei, Fructus Forsythiae, golden silkworm, with soak by water 1 time, fast baked wheaten cake is opened, slow fire 1-2h;
4) then Pseudobulbus Cremastrae Seu Pleiones, Radix Aucklandiae (Radix Vladimiriae), Herba Scutellariae Barbatae, Herba Hedyotidis Diffusae, the Rhizoma Atractylodis Macrocephalae, Cortex Phellodendri, Fructus Lycii, Fructus Ligustri Lucidi, Herba Taraxaci, Radix Pseudostellariae, Bulbus Fritillariae Cirrhosae, Spica Prunellae, Herba Cynomorii, Fructus Aurantii Immaturus, Squama Manis, Semen Vaccariae, Aloe are integrated with step 3) in, 2-4h is decocted at slow fire, filter, heating is concentrated, obtains concentrated solution;
5) by 1) fine powder and 4 of step) concentrated solution of step mixs homogeneously, and obtains mixed liquor;
6) to 5) add pharmaceutically acceptable adjuvant in the mixed liquor of step, make capsule.
Pharmaceutical preparation of the present invention be ointment by weight part ratio be 1: 0.5-10.0 mixture and pharmaceutically acceptable adjuvant make, be more preferably that the Chinese medicine composition of 1:1-5 and pharmaceutically acceptable adjuvant are made by weight part ratio.
Described Chinese medicine composition can be used for treating various cancer, is particluarly suitable for treating the application in breast carcinoma.
Pharmaceutical preparation of the present invention, through the continuous research of inventor, can also make water decoction, and better effects if, concrete preparation technology is as follows:
1) each crude drug is filtered out according to each proportioning raw materials, for subsequent use after remove impurity;
2) by Scorpio, Oletum Trogopterori, Radix Et Rhizoma Rhei, Fructus Forsythiae, golden silkworm, with the decoction 1 time of 2000ml water, slow fire is boiled, then slow fire 1-2h; Add Pseudobulbus Cremastrae Seu Pleiones, Radix Aucklandiae (Radix Vladimiriae), Herba Scutellariae Barbatae, Herba Hedyotidis Diffusae, the Rhizoma Atractylodis Macrocephalae, Cortex Phellodendri, Fructus Lycii, Fructus Ligustri Lucidi, Herba Taraxaci, Radix Pseudostellariae, Bulbus Fritillariae Cirrhosae, Spica Prunellae, Herba Cynomorii, Fructus Aurantii Immaturus, Squama Manis, Semen Vaccariae, Aloe, Radix Ginseng, Radix Pseudostellariae, the Radix Astragali wherein again, pour out decocting liquid 500ml
3) to step 2) in add water 500ml water, all pour out decocting liquid after continuing slow fire 2-4h;
4) combining step 2) and step 3) decocting liquid.
In the therapeutic process of the present invention in treatment breast carcinoma, take medicine of the present invention and have positive effect through 1 course for the treatment of, after taking 2-3 course for the treatment of continuously, tumor disappears substantially, appetite increases, the mental status is good, is almost recovered, the effective percentage 100% of patient, through call-on back by phone after 1 year, rebound rate is 0%, and have obvious advantage compared with existing invention technology, the present invention adopts pure Chinese traditional medicine dispensing, effectively can treat breast carcinoma, and not easily recur, have no side effect, preparation technology of the present invention comparatively simply can carry out suitability for industrialized production.
Specific embodiment
Embodiment 1:
Radix Ginseng 10g, Radix Astragali 10g, Pseudobulbus Cremastrae Seu Pleiones 20g, Scorpio 4g, Oletum Trogopterori 8g, Radix Aucklandiae (Radix Vladimiriae) 5g, Herba Scutellariae Barbatae 5g, Herba Hedyotidis Diffusae 10g, golden silkworm 10g, Rhizoma Atractylodis Macrocephalae 6g, Radix Et Rhizoma Rhei 4g, Cortex Phellodendri 15g, Fructus Lycii 5g, Fructus Ligustri Lucidi 5g, Herba Taraxaci 5g, Radix Pseudostellariae 5g, Bulbus Fritillariae Cirrhosae 15g, Spica Prunellae 10g, Herba Cynomorii 5g, Fructus Forsythiae 7g, Fructus Aurantii Immaturus 5g, Squama Manis 4g, Semen Vaccariae 15g, Aloe 5g.
Preparation technology:
1) Radix Ginseng, Radix Pseudostellariae, the Radix Astragali are broken into fine powder and cross 60 mesh sieves, for subsequent use;
2) by Pseudobulbus Cremastrae Seu Pleiones, Radix Aucklandiae (Radix Vladimiriae), Herba Scutellariae Barbatae, Herba Hedyotidis Diffusae, the Rhizoma Atractylodis Macrocephalae, Scorpio, Oletum Trogopterori, Radix Et Rhizoma Rhei, Fructus Forsythiae, golden silkworm, Cortex Phellodendri, Fructus Lycii, Fructus Ligustri Lucidi, Herba Taraxaci, Radix Pseudostellariae, Bulbus Fritillariae Cirrhosae, Spica Prunellae, Herba Cynomorii, Fructus Aurantii Immaturus, Squama Manis, Semen Vaccariae, Aloe remove impurity, for subsequent use;
3) by Scorpio, Oletum Trogopterori, Radix Et Rhizoma Rhei, Fructus Forsythiae, golden silkworm, with soak by water 1 time, fast baked wheaten cake is opened, slow fire 1-2h;
4) then Pseudobulbus Cremastrae Seu Pleiones, Radix Aucklandiae (Radix Vladimiriae), Herba Scutellariae Barbatae, Herba Hedyotidis Diffusae, the Rhizoma Atractylodis Macrocephalae, Cortex Phellodendri, Fructus Lycii, Fructus Ligustri Lucidi, Herba Taraxaci, Radix Pseudostellariae, Bulbus Fritillariae Cirrhosae, Spica Prunellae, Herba Cynomorii, Fructus Aurantii Immaturus, Squama Manis, Semen Vaccariae, Aloe are integrated with step 3) in, 2-4h is decocted at slow fire, filter, heating is concentrated, obtains concentrated solution;
5) by 1) fine powder and 4 of step) concentrated solution of step mixs homogeneously, and obtains mixed liquor;
6) to 5) add pharmaceutically acceptable adjuvant in the mixed liquor of step, make capsule.
Embodiment 2:
Radix Ginseng 60g, Radix Astragali 30g, Pseudobulbus Cremastrae Seu Pleiones 35g, Scorpio 10g, Oletum Trogopterori 12g, Radix Aucklandiae (Radix Vladimiriae) 20g, Herba Scutellariae Barbatae 15g, Herba Hedyotidis Diffusae 30g, golden silkworm 20g, Rhizoma Atractylodis Macrocephalae 10g, Radix Et Rhizoma Rhei 10g, Cortex Phellodendri 30g, Fructus Lycii 15g, Fructus Ligustri Lucidi 20g, Herba Taraxaci 20g, Radix Pseudostellariae 25g, Bulbus Fritillariae Cirrhosae 18g, Spica Prunellae 30g, Herba Cynomorii 17g, Fructus Forsythiae 23g, Fructus Aurantii Immaturus 16g, Squama Manis 10g, Semen Vaccariae 30g, Aloe 16g.
Preparation technology:
1) Radix Ginseng, Radix Pseudostellariae, the Radix Astragali are broken into fine powder and cross 60 mesh sieves, for subsequent use;
2) by Pseudobulbus Cremastrae Seu Pleiones, Radix Aucklandiae (Radix Vladimiriae), Herba Scutellariae Barbatae, Herba Hedyotidis Diffusae, the Rhizoma Atractylodis Macrocephalae, Scorpio, Oletum Trogopterori, Radix Et Rhizoma Rhei, Fructus Forsythiae, golden silkworm, Cortex Phellodendri, Fructus Lycii, Fructus Ligustri Lucidi, Herba Taraxaci, Radix Pseudostellariae, Bulbus Fritillariae Cirrhosae, Spica Prunellae, Herba Cynomorii, Fructus Aurantii Immaturus, Squama Manis, Semen Vaccariae, Aloe remove impurity, for subsequent use;
3) by Scorpio, Oletum Trogopterori, Radix Et Rhizoma Rhei, Fructus Forsythiae, golden silkworm, with soak by water 1 time, fast baked wheaten cake is opened, slow fire 1-2h;
4) then Pseudobulbus Cremastrae Seu Pleiones, Radix Aucklandiae (Radix Vladimiriae), Herba Scutellariae Barbatae, Herba Hedyotidis Diffusae, the Rhizoma Atractylodis Macrocephalae, Cortex Phellodendri, Fructus Lycii, Fructus Ligustri Lucidi, Herba Taraxaci, Radix Pseudostellariae, Bulbus Fritillariae Cirrhosae, Spica Prunellae, Herba Cynomorii, Fructus Aurantii Immaturus, Squama Manis, Semen Vaccariae, Aloe are integrated with step 3) in, 2-4h is decocted at slow fire, filter, heating is concentrated, obtains concentrated solution;
5) by 1) fine powder and 4 of step) concentrated solution of step mixs homogeneously, and obtains mixed liquor;
6) to 5) add pharmaceutically acceptable adjuvant in the mixed liquor of step, make capsule.
Embodiment 3:
Radix Ginseng 20g, Radix Astragali 15g, Pseudobulbus Cremastrae Seu Pleiones 25g, Scorpio 6g, Oletum Trogopterori 10g, Radix Aucklandiae (Radix Vladimiriae) 10g, Herba Scutellariae Barbatae 10g, Herba Hedyotidis Diffusae 15g, golden silkworm 15g, Rhizoma Atractylodis Macrocephalae 8g, Radix Et Rhizoma Rhei 6g, Cortex Phellodendri 20g, Fructus Lycii 10g, Fructus Ligustri Lucidi 15g, Herba Taraxaci 15g, Radix Pseudostellariae 15g, Bulbus Fritillariae Cirrhosae 15g, Spica Prunellae 15g, Herba Cynomorii 10g, Fructus Forsythiae 10-17g, Fructus Aurantii Immaturus 8g, Squama Manis 8g, Semen Vaccariae 20g, Aloe 9g.
Preparation technology:
1) Radix Ginseng, Radix Pseudostellariae, the Radix Astragali are broken into fine powder and cross 60 mesh sieves, for subsequent use;
2) by Pseudobulbus Cremastrae Seu Pleiones, Radix Aucklandiae (Radix Vladimiriae), Herba Scutellariae Barbatae, Herba Hedyotidis Diffusae, the Rhizoma Atractylodis Macrocephalae, Scorpio, Oletum Trogopterori, Radix Et Rhizoma Rhei, Fructus Forsythiae, golden silkworm, Cortex Phellodendri, Fructus Lycii, Fructus Ligustri Lucidi, Herba Taraxaci, Radix Pseudostellariae, Bulbus Fritillariae Cirrhosae, Spica Prunellae, Herba Cynomorii, Fructus Aurantii Immaturus, Squama Manis, Semen Vaccariae, Aloe remove impurity, for subsequent use;
3) by Scorpio, Oletum Trogopterori, Radix Et Rhizoma Rhei, Fructus Forsythiae, golden silkworm, with soak by water 1 time, fast baked wheaten cake is opened, slow fire 1-2h;
4) then Pseudobulbus Cremastrae Seu Pleiones, Radix Aucklandiae (Radix Vladimiriae), Herba Scutellariae Barbatae, Herba Hedyotidis Diffusae, the Rhizoma Atractylodis Macrocephalae, Cortex Phellodendri, Fructus Lycii, Fructus Ligustri Lucidi, Herba Taraxaci, Radix Pseudostellariae, Bulbus Fritillariae Cirrhosae, Spica Prunellae, Herba Cynomorii, Fructus Aurantii Immaturus, Squama Manis, Semen Vaccariae, Aloe are integrated with step 3) in, 2-4h is decocted at slow fire, filter, heating is concentrated, obtains concentrated solution;
5) by 1) fine powder and 4 of step) concentrated solution of step mixs homogeneously, and obtains mixed liquor;
6) to 5) add pharmaceutically acceptable adjuvant in the mixed liquor of step, make capsule.
Embodiment 4:
Radix Ginseng 50 parts, the Radix Astragali 25 parts, Pseudobulbus Cremastrae Seu Pleiones 30 parts, Scorpio 10 parts, Oletum Trogopterori 12 parts, Radix Aucklandiae (Radix Vladimiriae) 15 parts, Herba Scutellariae Barbatae 15 parts, Herba Hedyotidis Diffusae 25 parts, golden silkworm 20 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, Radix Et Rhizoma Rhei 8 parts, Cortex Phellodendri 25 parts, Fructus Lycii 15 parts, Fructus Ligustri Lucidi 20 parts, Herba Taraxaci 20 parts, Radix Pseudostellariae 20 parts, Bulbus Fritillariae Cirrhosae 18 parts, Spica Prunellae 25 parts, Herba Cynomorii 12 parts, Fructus Forsythiae 17 parts, Fructus Aurantii Immaturus 12 parts, Squama Manis 10 parts, Semen Vaccariae 30 parts, Aloe 13 parts.
Preparation technology:
1) Radix Ginseng, Radix Pseudostellariae, the Radix Astragali are broken into fine powder and cross 60 mesh sieves, for subsequent use;
2) by Pseudobulbus Cremastrae Seu Pleiones, Radix Aucklandiae (Radix Vladimiriae), Herba Scutellariae Barbatae, Herba Hedyotidis Diffusae, the Rhizoma Atractylodis Macrocephalae, Scorpio, Oletum Trogopterori, Radix Et Rhizoma Rhei, Fructus Forsythiae, golden silkworm, Cortex Phellodendri, Fructus Lycii, Fructus Ligustri Lucidi, Herba Taraxaci, Radix Pseudostellariae, Bulbus Fritillariae Cirrhosae, Spica Prunellae, Herba Cynomorii, Fructus Aurantii Immaturus, Squama Manis, Semen Vaccariae, Aloe remove impurity, for subsequent use;
3) by Scorpio, Oletum Trogopterori, Radix Et Rhizoma Rhei, Fructus Forsythiae, golden silkworm, with soak by water 1 time, fast baked wheaten cake is opened, slow fire 1-2h;
4) then Pseudobulbus Cremastrae Seu Pleiones, Radix Aucklandiae (Radix Vladimiriae), Herba Scutellariae Barbatae, Herba Hedyotidis Diffusae, the Rhizoma Atractylodis Macrocephalae, Cortex Phellodendri, Fructus Lycii, Fructus Ligustri Lucidi, Herba Taraxaci, Radix Pseudostellariae, Bulbus Fritillariae Cirrhosae, Spica Prunellae, Herba Cynomorii, Fructus Aurantii Immaturus, Squama Manis, Semen Vaccariae, Aloe are integrated with step 3) in, 2-4h is decocted at slow fire, filter, heating is concentrated, obtains concentrated solution;
5) by 1) fine powder and 4 of step) concentrated solution of step mixs homogeneously, and obtains mixed liquor;
6) to 5) add pharmaceutically acceptable adjuvant in the mixed liquor of step, make capsule.
Embodiment 5:
Radix Ginseng 35g, Radix Astragali 20g, Pseudobulbus Cremastrae Seu Pleiones 27g, Scorpio 9g, Oletum Trogopterori 10g, Radix Aucklandiae (Radix Vladimiriae) 10g, Herba Scutellariae Barbatae 15g, Herba Hedyotidis Diffusae 20g, golden silkworm 20g, Rhizoma Atractylodis Macrocephalae 10g, Radix Et Rhizoma Rhei 7g, Cortex Phellodendri 25g, Fructus Lycii 12g, Fructus Ligustri Lucidi 18g, Herba Taraxaci 20g, Radix Pseudostellariae 15g, Bulbus Fritillariae Cirrhosae 18g, Spica Prunellae 25g, Herba Cynomorii 10g, Fructus Forsythiae 13g, Fructus Aurantii Immaturus 11g, Squama Manis 9g, Semen Vaccariae 25g, Aloe 10g.
Preparation technology:
1) Radix Ginseng, Radix Pseudostellariae, the Radix Astragali are broken into fine powder and cross 60 mesh sieves, for subsequent use;
2) by Pseudobulbus Cremastrae Seu Pleiones, Radix Aucklandiae (Radix Vladimiriae), Herba Scutellariae Barbatae, Herba Hedyotidis Diffusae, the Rhizoma Atractylodis Macrocephalae, Scorpio, Oletum Trogopterori, Radix Et Rhizoma Rhei, Fructus Forsythiae, golden silkworm, Cortex Phellodendri, Fructus Lycii, Fructus Ligustri Lucidi, Herba Taraxaci, Radix Pseudostellariae, Bulbus Fritillariae Cirrhosae, Spica Prunellae, Herba Cynomorii, Fructus Aurantii Immaturus, Squama Manis, Semen Vaccariae, Aloe remove impurity, for subsequent use;
3) by Scorpio, Oletum Trogopterori, Radix Et Rhizoma Rhei, Fructus Forsythiae, golden silkworm, with soak by water 1 time, fast baked wheaten cake is opened, slow fire 1-2h;
4) then Pseudobulbus Cremastrae Seu Pleiones, Radix Aucklandiae (Radix Vladimiriae), Herba Scutellariae Barbatae, Herba Hedyotidis Diffusae, the Rhizoma Atractylodis Macrocephalae, Cortex Phellodendri, Fructus Lycii, Fructus Ligustri Lucidi, Herba Taraxaci, Radix Pseudostellariae, Bulbus Fritillariae Cirrhosae, Spica Prunellae, Herba Cynomorii, Fructus Aurantii Immaturus, Squama Manis, Semen Vaccariae, Aloe are integrated with step 3) in, 2-4h is decocted at slow fire, filter, heating is concentrated, obtains concentrated solution;
5) by 1) fine powder and 4 of step) concentrated solution of step mixs homogeneously, and obtains mixed liquor;
6) to 5) add pharmaceutically acceptable adjuvant in the mixed liquor of step, make capsule.
Embodiment 6:
Radix Ginseng 35g, Radix Astragali 20g, Pseudobulbus Cremastrae Seu Pleiones 27g, Scorpio 9g, Oletum Trogopterori 10g, Radix Aucklandiae (Radix Vladimiriae) 10g, Herba Scutellariae Barbatae 15g, Herba Hedyotidis Diffusae 20g, golden silkworm 20g, Rhizoma Atractylodis Macrocephalae 10g, Radix Et Rhizoma Rhei 7g, Cortex Phellodendri 25g, Fructus Lycii 12g, Fructus Ligustri Lucidi 18g, Herba Taraxaci 20g, Radix Pseudostellariae 15g, Bulbus Fritillariae Cirrhosae 18g, Spica Prunellae 25g, Herba Cynomorii 10g, Fructus Forsythiae 13g, Fructus Aurantii Immaturus 11g, Squama Manis 9g, Semen Vaccariae 25g, Aloe 10g.
Preparation technology:
1) each crude drug is filtered out according to each proportioning raw materials, for subsequent use after remove impurity;
2) by Scorpio, Oletum Trogopterori, Radix Et Rhizoma Rhei, Fructus Forsythiae, golden silkworm, with the decoction 1 time of 2000ml water, slow fire is boiled, then slow fire 1-2h; Add Pseudobulbus Cremastrae Seu Pleiones, Radix Aucklandiae (Radix Vladimiriae), Herba Scutellariae Barbatae, Herba Hedyotidis Diffusae, the Rhizoma Atractylodis Macrocephalae, Cortex Phellodendri, Fructus Lycii, Fructus Ligustri Lucidi, Herba Taraxaci, Radix Pseudostellariae, Bulbus Fritillariae Cirrhosae, Spica Prunellae, Herba Cynomorii, Fructus Aurantii Immaturus, Squama Manis, Semen Vaccariae, Aloe, Radix Ginseng, Radix Pseudostellariae, the Radix Astragali wherein again, pour out decocting liquid 500ml
3) to step 2) in add water 500ml water, all pour out decocting liquid after continuing slow fire 2-4h;
4) combining step 2) and step 3) decocting liquid.
Embodiment 7: clinical trial
7.1, clinical observation
Clinical data: the outpatient service and inpatient totally 117 examples that are selected from June, 2011 to 2014 year JIUYUE.Age is 31-61 year, average 46 years old.
7.2, diagnostic criteria:
Tcm diagnosis standard:
Patient has pain mid-term, the existing Shen Chi of arteries and veins, the pain touched, and multipotency activist easily control, and the person that do not move pushed away takes effect extremely slow for the later stage.
Western medicine diagnose standard:
Can pusher be benign tumor; What push away does not move person for cancer, and chemotherapy can not ensure not shift with operation.
7.3, Therapeutic Method:
Take medicine of the present invention, water decoction, sooner or later take at twice.It within 15 days, is 1 course for the treatment of.
7.4, efficacy assessment standard:
Effective: tumor reduces obviously, and even disappear, pain alleviates comparatively obvious.
Take a turn for the better: pain alleviates, and tumor reduces to some extent.
Invalid: not reach treatment standard person or sb.'s illness took a turn for the worse.
Effective percentage: (effective+to take a turn for the better)/patient populations.
Bounce-back is individual: the effective individuality recurred again with taking a turn for the better after 1 year.
Rebound rate: the effective recurrence again with taking a turn for the better after 1 year.
7.5, therapeutic outcome:
After the treatment of 2 courses for the treatment of, obvious effective rate is 97.4%, and effective percentage is 100%.Follow up a case by regular visits to after 1 year, relapse rate only has 2 examples, and rebound rate is 1.7%.Detailed results is in table 1.
7.6, toxic and side effects analysis
In the 117 routine patients observed, only have 1 routine laxativeness, occur that the probability of side reaction is only 0.8% after taking Chinese medicine of the present invention, dispose side reaction through suiting the medicine to the illness and disappear, all the other are without any side effects.
In sum, the present invention is used for the treatment of the medicine of breast carcinoma, through clinical trial, show that it effectively can suppress breast cancer development, improve patients symptomatic, sign, and without obvious toxic-side effects, rebound rate is little.
Embodiment 8: the classic and clinical case
Case 1: Mrs Qi, female, 46 years old, Shandong Tancheng people, within 2005, suffer from breast cancer, be diagnosed as mastitis through county people's hospital, long-time treatment still recurrent exerbation, within 2012, be diagnosed as breast carcinoma through local county people's hospital, carried out my institute's treatment afterwards upon somebody's introduction, with the water decoction taking the embodiment of the present invention 5 after diagnosis, entirely healed after treating a course for the treatment of, recover normal 1 year call-on back by phone afterwards, do not recur so far.
Case 2: Mrs Qin, 36 years old, people from Xuzhou, 2012 in women's checking process of locality, check that left breast touches the tumor having " Fructus Fragariae Ananssae " size, have a strong impact on Working Life, arrive when districts and cities' hospitalize subsequently, the state of an illness does not take a turn for the better, and worsen further, introduce my institute through friend and check treatment, the capsule of the embodiment of the present invention 6 is taken after diagnosis, after treating a course for the treatment of, the tumor of patient obviously reduces, after taking 1 course for the treatment of of medicine of the present invention, Quan Yu, recover normal, tumor disappearance, recover normal Working Life, call-on back by phone after 1 year, so far do not recur.
Case 3: Mrs Yang, 52 years old, people from Linshu, Shandong, 2013 when working in farmland, suddenly think that the right hand is unable, touch the lump having soybean grain size, to the People's Hospital under the accompanying of layman immediately, right side breast cancer is diagnosed as through ultrasound diagnosis, axillary lymphatic metastasis, carry out resection operation afterwards, and note paclitaxel injection, then chemotherapy, with serious side reaction, side reaction is serious, feel sick, vomiting, leukocyte declines, family is absorbed in misery, I treated at institute afterwards, start the capsule taking the present embodiment 6, after 1 course for the treatment of, the state of an illness takes a turn for the better to some extent, then have and then take two courses for the treatment of, be almost recovered, side effect disappears, life can take care of oneself, call-on back by phone after 1 year, live very happy.
Case 4: Mrs Li, 44 years old, people from Linyi, Shandong, because of parents divorce, live in extremely gloomy environment for a long time, in January, 2014 feels that left breast has sense of discomfort, do not take notice of, after more and more serious, in May, 2014 checks through the People's Hospital of city, be diagnosed as left breast cancer, excision both sides breast, post-surgical chemotherapy one-period, the side effect such as alopecia, live in depression for a long time, in painful life, after hear pharmaceutical preparation of the present invention, come my institute to check, after taking a course for the treatment of of this formula, the state of an illness takes a turn for the better to some extent, depressive emotion disappears, after find second half, patient is made to obtain second time life, fully recover after continuing to take a course for the treatment of, call-on back by phone after 1 year, live very happy.
Case 5: Mrs Tian, 35 years old, Nanyang, henan people, in January, 2015 felt that breast is not suitable for, and come my institute and check, have the lump of 8cm × 8cm through CT examination right breast, learn by inquiry, field during suckling, thinks it is normal phenomenon.Through the suggestion excision of too much household people hospital, come my institute's demand remedial measure, take the capsule preparations of the embodiment of the present invention 6, after the course for the treatment of, tumor regression, only has 4cm × 2.5cm through CT examination, pain disappears, and then take 2 cycles, tumor obviously disappears.Call-on back by phone after 1 year, not recurrence.
Case 6: Mrs Ma, 44 years old, people from Linyi, Shandong, in June, 2015 health check-up finds that the newborn pain in left side has a lump to do breast left and right resection operation immediately, then chemotherapy 1 week, and side effect is very big, physical distress, appetite reduces, sleep extreme difference, myasthenia of limbs, adopt western medicines in treatment all not have obvious therapeutic effect, after adopting two courses for the treatment of of medicine of the present invention, pain fades away, appetite increases, and sleep takes a turn for the better, and muscle power increases, the mental status improves, call-on back by phone after 1 year, not recurrence.

Claims (8)

1. treat the Chinese medicine composition of breast carcinoma for one kind, it is characterized in that, be made up of the crude drug of following weight portion: Radix Ginseng 10-60 part, Radix Astragali 10-30 part, Pseudobulbus Cremastrae Seu Pleiones 20-35 part, Scorpio 4-10 part, Oletum Trogopterori 8-12 part, Radix Aucklandiae (Radix Vladimiriae) 5-20 part, Herba Scutellariae Barbatae 5-15 part, Herba Hedyotidis Diffusae 10-30 part, gold silkworm 10-20 part, Rhizoma Atractylodis Macrocephalae 6-10 part, Radix Et Rhizoma Rhei 4-10 part, Cortex Phellodendri 15-30 part, Fructus Lycii 5-15 part, Fructus Ligustri Lucidi 5-20 part, Herba Taraxaci 5-20 part, Radix Pseudostellariae 5-25 part, Bulbus Fritillariae Cirrhosae 15-18 part, Spica Prunellae 10-30 part, Herba Cynomorii 5-17 part, Fructus Forsythiae 7-23 part, Fructus Aurantii Immaturus 5-16 part, Squama Manis 4-10 part, Semen Vaccariae 15-30 part, Aloe 5-16 part.
2. Chinese medicine composition according to claim 1, it is characterized in that, be made up of the crude drug of following weight portion: Radix Ginseng 20-50 part, Radix Astragali 15-25 part, Pseudobulbus Cremastrae Seu Pleiones 25-30 part, Scorpio 6-10 part, Oletum Trogopterori 10-12 part, Radix Aucklandiae (Radix Vladimiriae) 10-15 part, Herba Scutellariae Barbatae 10-15 part, Herba Hedyotidis Diffusae 15-25 part, gold silkworm 15-20 part, Rhizoma Atractylodis Macrocephalae 8-10 part, Radix Et Rhizoma Rhei 6-8 part, Cortex Phellodendri 20-25 part, Fructus Lycii 10-15 part, Fructus Ligustri Lucidi 15-20 part, Herba Taraxaci 15-20 part, Radix Pseudostellariae 15-20 part, Bulbus Fritillariae Cirrhosae 15-18 part, Spica Prunellae 15-25 part, Herba Cynomorii 10-12 part, Fructus Forsythiae 10-17 part, Fructus Aurantii Immaturus 8-12 part, Squama Manis 8-10 part, Semen Vaccariae 20-30 part, Aloe 9-13 part.
3. Chinese medicine composition according to claim 1, it is characterized in that, be made up of the crude drug of following weight portion: Radix Ginseng 35 parts, the Radix Astragali 20 parts, Pseudobulbus Cremastrae Seu Pleiones 27 parts, Scorpio 9 parts, Oletum Trogopterori 10 parts, Radix Aucklandiae (Radix Vladimiriae) 10 parts, Herba Scutellariae Barbatae 15 parts, Herba Hedyotidis Diffusae 20 parts, golden silkworm 20 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, Radix Et Rhizoma Rhei 7 parts, Cortex Phellodendri 25 parts, Fructus Lycii 12 parts, Fructus Ligustri Lucidi 18 parts, Herba Taraxaci 20 parts, Radix Pseudostellariae 15 parts, Bulbus Fritillariae Cirrhosae 18 parts, Spica Prunellae 25 parts, Herba Cynomorii 10 parts, Fructus Forsythiae 13 parts, Fructus Aurantii Immaturus 11 parts, Squama Manis 9 parts, Semen Vaccariae 25 parts, Aloe 10 parts.
4. prepare a Chinese medicine composition according to claim 1, it is characterized in that, concrete step is:
1) Radix Ginseng, Radix Pseudostellariae, the Radix Astragali are broken into fine powder and cross 60 mesh sieves, for subsequent use;
2) by Pseudobulbus Cremastrae Seu Pleiones, Radix Aucklandiae (Radix Vladimiriae), Herba Scutellariae Barbatae, Herba Hedyotidis Diffusae, the Rhizoma Atractylodis Macrocephalae, Scorpio, Oletum Trogopterori, Radix Et Rhizoma Rhei, Fructus Forsythiae, golden silkworm, Cortex Phellodendri, Fructus Lycii, Fructus Ligustri Lucidi, Herba Taraxaci, Radix Pseudostellariae, Bulbus Fritillariae Cirrhosae, Spica Prunellae, Herba Cynomorii, Fructus Aurantii Immaturus, Squama Manis, Semen Vaccariae, Aloe remove impurity, for subsequent use;
3) by Scorpio, Oletum Trogopterori, Radix Et Rhizoma Rhei, Fructus Forsythiae, golden silkworm, with soak by water 1 time, fast baked wheaten cake is opened, slow fire 1-2h;
4) then Pseudobulbus Cremastrae Seu Pleiones, Radix Aucklandiae (Radix Vladimiriae), Herba Scutellariae Barbatae, Herba Hedyotidis Diffusae, the Rhizoma Atractylodis Macrocephalae, Cortex Phellodendri, Fructus Lycii, Fructus Ligustri Lucidi, Herba Taraxaci, Radix Pseudostellariae, Bulbus Fritillariae Cirrhosae, Spica Prunellae, Herba Cynomorii, Fructus Aurantii Immaturus, Squama Manis, Semen Vaccariae, Aloe are integrated with step 3) in, 2-4h is decocted at slow fire, filter, heating is concentrated, obtains concentrated solution;
5) by 1) fine powder and 4 of step) concentrated solution of step mixs homogeneously, and obtains mixed liquor;
6) to 5) add pharmaceutically acceptable adjuvant in the mixed liquor of step, make capsule.
5. the preparation method of Chinese medicine composition according to claim 4, is characterized in that: described capsule by weight part ratio be 1: 0.5-10.0 mixture and pharmaceutically acceptable adjuvant make.
6. the preparation method of Chinese medicine composition according to claim 5, is characterized in that: described capsule by weight part ratio be 1: 1-5 mixture and pharmaceutically acceptable adjuvant make.
7. prepare a preparation method for Chinese medicine composition according to claim 1, it is characterized in that, concrete step can also be:
1) each crude drug is filtered out according to each proportioning raw materials, for subsequent use after remove impurity;
2) by Scorpio, Oletum Trogopterori, Radix Et Rhizoma Rhei, Fructus Forsythiae, golden silkworm, with the decoction 1 time of 2000ml water, slow fire is boiled, then slow fire 1-2h; Add Pseudobulbus Cremastrae Seu Pleiones, Radix Aucklandiae (Radix Vladimiriae), Herba Scutellariae Barbatae, Herba Hedyotidis Diffusae, the Rhizoma Atractylodis Macrocephalae, Cortex Phellodendri, Fructus Lycii, Fructus Ligustri Lucidi, Herba Taraxaci, Radix Pseudostellariae, Bulbus Fritillariae Cirrhosae, Spica Prunellae, Herba Cynomorii, Fructus Aurantii Immaturus, Squama Manis, Semen Vaccariae, Aloe, Radix Ginseng, Radix Pseudostellariae, the Radix Astragali wherein again, pour out decocting liquid 500ml;
3) to step 2) in add water 500ml water, all pour out decocting liquid after continuing slow fire 2-4h;
4) combining step 2) and step 3) decocting liquid.
8. the Chinese medicine composition according to any one of claim 1-7, is characterized in that: the application of described Chinese medicine composition in treatment breast carcinoma.
CN201510686245.9A 2015-10-20 2015-10-20 Traditional Chinese medicinal composition for treating breast cancer and application thereof Pending CN105168944A (en)

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Application publication date: 20151223