CN105168856B - Treat ischaemia-reperfusion slow arrhythmia Chinese medicine preparation and preparation method thereof - Google Patents
Treat ischaemia-reperfusion slow arrhythmia Chinese medicine preparation and preparation method thereof Download PDFInfo
- Publication number
- CN105168856B CN105168856B CN201510610403.2A CN201510610403A CN105168856B CN 105168856 B CN105168856 B CN 105168856B CN 201510610403 A CN201510610403 A CN 201510610403A CN 105168856 B CN105168856 B CN 105168856B
- Authority
- CN
- China
- Prior art keywords
- radix
- reperfusion
- ischaemia
- chinese medicine
- medicine preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
Ischaemia-reperfusion slow arrhythmia Chinese medicine preparation is treated the invention discloses a kind of, it is formulated by weight by following raw material：9 18 g of cassia twig, 6 15 g of honey-fried licorice root, 36 g of Radix Notoginseng powder, 8 12 g of Radix Aconiti Lateralis Preparata, 6 12 g of ginseng, 12 18 g of Radix Ophiopogonis, 6 12 g of Schisandra chinensis, 15 30 g of Radix Salviae Miltiorrhizae, 10 20 g of Radix Angelicae Sinensis.The present invention is prepared through science, drug safety, can be effectively used for treatment ischaemia-reperfusion slow arrhythmia patient, is the innovation treated on ischaemia-reperfusion slow arrhythmia drug.Abundant raw materials of the present invention, preparation method is simple, easy to produce, convenient to take, and effect is good, and economic and social benefit is huge.
Description
Technical field
The present invention relates to Chinese medicine compositions, particularly with regard to a kind of Chinese patent medicine preparation for treating gestation hypertension disease.
Background technology
Myocardial ischemia-reperfusion injury refers to the coronary flow imaging occluded in coronary heart attack, infarcted region blood perfusion
After reconstruction in a period of time, former ischemic myocardium has occurred restores preceding even more serious damage compared with blood supply, blood pressure rapid drawdown, heart work(occurs
Can not complete, arrhythmia cordis the phenomenon that sb.'s illness took a turn for the worse such as even die suddenly.Reperfusion arrhythmia is myocardial ischemia-reperfusion injury master
One of clinical manifestation wanted, incidence may be up to 80% or more, including slow arrhythmia and tachyarrhythmia, wherein
Slow arrhythmia refers to after myocardial ischemia-reperfusion occurs one characterized by by heart rate, slow, ventricular rate is less than 60 beats/min
Class arrhythmia cordis.Traditional anti-arrhythmia chemicals are by directly or indirectly blocking myocardial cell ion channel or receptor to play
Antiarrhythmic effect, however famous cardiac arrhythmia inhibits experiment（Cardiac Arrhythmia Suppression
Test,CAST）Result query is proposed to its safety.Traditional Chinese medicine prevention myocardial ischemia-reperfusion arrhythmia cordis is either faced
Bed and experimental study all achieve significant curative effect, and adverse reaction is few, have unique advantage.Therefore, new treatment is developed to lack
The drug of blood Reperfu- sion slow arrhythmia is imperative.
Invention content
Present invention aims at a kind of Chinese medicine preparation for treating ischaemia-reperfusion slow arrhythmia is provided, it can subtract
The dosage of few anti-arrhythmia chemicals, effective the problems such as solving patient uncomfortable in chest, palpitaition, shortness of breath.
The present invention is achieved by the following technical solutions：
It is a kind of to treat ischaemia-reperfusion slow arrhythmia Chinese medicine preparation, it prepared by weight by following raw material and
At：
Cassia twig 9-18 g, honey-fried licorice root 6-15 g, Radix Notoginseng powder 3-6 g, Radix Aconiti Lateralis Preparata 8-12 g, ginseng 6-12 g, Radix Ophiopogonis
12-18 g, Schisandra chinensis 6-12 g, Radix Salviae Miltiorrhizae 15-30 g, Radix Angelicae Sinensis 10-20 g.
The present invention best weight ratio be：
Cassia twig 12g, honey-fried licorice root 9g, Radix Notoginseng powder 4g, Radix Aconiti Lateralis Preparata 10g, 9 g of ginseng, 15 g of Radix Ophiopogonis, 9 g of Schisandra chinensis, pellet
Join 22 g, Radix Angelicae Sinensis 15g.
The preparation method of the treatment ischaemia-reperfusion slow arrhythmia Chinese medicine preparation, it includes the following steps：
Said components cassia twig, honey-fried licorice root, Radix Notoginseng powder, Radix Aconiti Lateralis Preparata, ginseng, Radix Ophiopogonis, Schisandra chinensis, Radix Salviae Miltiorrhizae, Radix Angelicae Sinensis are blended in
Together, it adds water to cook twice, the water of 6 to 8 times of its weight is added every time, decoct 1 to 1.5 hour every time, merge decocting liquid twice, mistake
Filter, is concentrated into the 1/4 to 1/6 of amount of water, obtain medical treatment ischaemia-reperfusion slow arrhythmia Chinese medicine preparation.
It is an advantage of the invention that：The present invention is prepared through science, has the effect of warming heart yang, invigorating spleen and kidney, effective for
Ischaemia-reperfusion slow arrhythmia is treated, and achieves satisfied effect through clinical test, related clinical data is as follows：
One, the standard of case is selected
With typical clinical manifestation（Chest distress and palpitation symptoms, shortness of breath and fatigue, four limbs are not warm etc.）It is in dynamic evolution with electrocardiogram（ST
Section is forced down and ventricular rate is less than 60 beats/min）Patient, it is all that there is above-mentioned standard person's alternatively case, be used in combination in the present invention
Medicine, which is given, treats.
Two, diagnostic criteria
It is all that there is chest distress and palpitation symptoms, shortness of breath and fatigue, the typical clinical manifestations such as four limbs are not warm, and electrocardiogram is forced down in ST sections,
Ventricular rate is less than 60 beats/min, and doctor trained in Western medicine is diagnosed as the patient of coronary heart disease.
Three, therapeutic scheme
It is all to make a definite diagnosis the ischaemia-reperfusion slow arrhythmia patient for meeting case selection standard, take the present invention's
Chinese medicine, which is given, treats, early daily, late each primary, each taking 200~300ml, per 15 days as one therapeutic course, is counted after a course for the treatment of
Curative effect.
Four, efficacy assessment standard
It cures：So-called symptom all disappears in diagnostic criteria, and electrocardiogram returns to normal；
It improves：So-called symptom has mitigation or substantially reduced in diagnostic criteria, and ECG examination has improvement；
In vain：So-called symptom and ECG examination are without improvement in diagnostic criteria, or even have the gesture of exacerbation.
Five, statistical procedures
According to the standard of selection case and after making a definite diagnosis to suffer from 122 people of ischaemia-reperfusion slow arrhythmia patient into
Row medication treatment, wherein male 60 people, 62 people of female is the oldest 73 years old, 40 years old minimum；The course of disease 1~20 year.As a result efficient
Reach 95.9%, specific statistics is as follows:
During above-mentioned patient takes medicine, any adverse reaction is not found, shows that curative effect is stablized, drug safety.
Six, conclusion
From the above, it is seen that curative effect of the present invention is high, curative effect is up to 95.9%, and drug safety, can be effectively used for treatment and lacks
Blood Reperfu- sion slow arrhythmia patient is the innovation treated on ischaemia-reperfusion slow arrhythmia drug, this
Invention abundant raw materials, preparation method is simple, easy to produce, convenient to take, and effect is good, and economic and social benefit is huge.
Specific implementation mode
Embodiment 1：The treatment ischaemia-reperfusion slow arrhythmia Chinese medicine preparation of the present invention, it is pressed by following raw material
Parts by weight are formulated：Cassia twig 12g, honey-fried licorice root 9g, Radix Notoginseng powder 4g, Radix Aconiti Lateralis Preparata 10g, 9 g of ginseng, 15 g of Radix Ophiopogonis, Schisandra chinensis
9 g, 22 g of Radix Salviae Miltiorrhizae, Radix Angelicae Sinensis 15g.
The preparation method of the treatment ischaemia-reperfusion slow arrhythmia Chinese medicine preparation, it includes the following steps：
Said components are mixed, are added water to cook twice.The water of 8 times of its weight is added for the first time, it is small to decoct 1.5
When, first time decocting liquid is obtained, second of the water that former 6 times of drug weight is added in the dregs of a decoction decocts 1 hour, obtains second of decocting liquid, closes
And decocting liquid, filtering are concentrated into the 1/4 to 1/6 of amount of water twice, obtain in treatment ischaemia-reperfusion slow arrhythmia
Medicine preparation.
The instructions of taking of Chinese medicine preparation of the present invention is：It is early daily, late each primary, each taking 200~300ml, every 15 days
It is as a treatment course, count curative effect after a course for the treatment of.
Embodiment 2：The treatment ischaemia-reperfusion slow arrhythmia Chinese medicine preparation of the present invention, it is pressed by following raw material
Parts by weight are formulated：9 g of cassia twig, 6 g of honey-fried licorice root, 3 g of Radix Notoginseng powder, 8 g of Radix Aconiti Lateralis Preparata, 6 g of ginseng, 12 g of Radix Ophiopogonis,
6 g of Schisandra chinensis, 15 g of Radix Salviae Miltiorrhizae, 10 g of Radix Angelicae Sinensis.
The preparation method of the treatment ischaemia-reperfusion slow arrhythmia Chinese medicine preparation, it includes the following steps：
Said components are mixed, are added water to cook twice.The water of 8 times of its weight is added for the first time, it is small to decoct 1.5
When, first time decocting liquid is obtained, second of the water that former 6 times of drug weight is added in the dregs of a decoction decocts 1 hour, obtains second of decocting liquid, closes
And decocting liquid, filtering are concentrated into the 1/4 to 1/6 of amount of water twice, obtain in treatment ischaemia-reperfusion slow arrhythmia
Medicine preparation.
The instructions of taking of Chinese medicine preparation of the present invention is：It is early daily, late each primary, each taking 200~300ml, every 15 days
It is as a treatment course, count curative effect after a course for the treatment of.
Embodiment 3：The treatment ischaemia-reperfusion slow arrhythmia Chinese medicine preparation of the present invention, it is pressed by following raw material
Parts by weight are formulated：18 g of cassia twig, 15 g of honey-fried licorice root, 6 g of Radix Notoginseng powder, 12 g of Radix Aconiti Lateralis Preparata, 12 g of ginseng, 18 g of Radix Ophiopogonis, five
12 g of taste, 30 g of Radix Salviae Miltiorrhizae, 20 g of Radix Angelicae Sinensis.
The preparation method of the treatment ischaemia-reperfusion slow arrhythmia Chinese medicine preparation, it includes the following steps：
Said components are mixed, are added water to cook twice.The water of 8 times of its weight is added for the first time, it is small to decoct 1.5
When, first time decocting liquid is obtained, second of the water that former 6 times of drug weight is added in the dregs of a decoction decocts 1 hour, obtains second of decocting liquid, closes
And decocting liquid, filtering are concentrated into the 1/4 to 1/6 of amount of water twice, obtain in treatment ischaemia-reperfusion slow arrhythmia
Medicine preparation.
The instructions of taking of Chinese medicine preparation of the present invention is：It is early daily, late each primary, each taking 200~300ml, every 15 days
It is as a treatment course, count curative effect after a course for the treatment of.
Claims (3)
1. a kind for the treatment of ischaemia-reperfusion slow arrhythmia Chinese medicine preparation, it is characterized in that：It by following raw material by weight
Part is formulated：
Cassia twig 9-18 g, honey-fried licorice root 6-15 g, Radix Notoginseng powder 3-6 g, Radix Aconiti Lateralis Preparata 8-12 g, ginseng 6-12 g, Radix Ophiopogonis 12-
18 g, Schisandra chinensis 6-12 g, Radix Salviae Miltiorrhizae 15-30 g, Radix Angelicae Sinensis 10-20 g.
2. treatment ischaemia-reperfusion slow arrhythmia Chinese medicine preparation according to claim 1, it is characterized in that：It by
Following raw material is formulated by weight：
Cassia twig 12g, honey-fried licorice root 9g, Radix Notoginseng powder 4g, Radix Aconiti Lateralis Preparata 10g, 9 g of ginseng, 15 g of Radix Ophiopogonis, 9 g of Schisandra chinensis, Radix Salviae Miltiorrhizae 22
G, Radix Angelicae Sinensis 15g.
3. treating the system of ischaemia-reperfusion slow arrhythmia Chinese medicine preparation according to claim 1 to 2 any one of them
Preparation Method, it is characterized in that：It includes the following steps：
Said components cassia twig, honey-fried licorice root, Radix Notoginseng powder, Radix Aconiti Lateralis Preparata, ginseng, Radix Ophiopogonis, Schisandra chinensis, Radix Salviae Miltiorrhizae, Radix Angelicae Sinensis are mixed,
It adds water to cook twice, the water of 6 to 8 times of its weight is added every time, decoct 1 to 1.5 hour every time, merge decocting liquid twice, filtering is dense
It is reduced to the 1/4 to 1/6 of amount of water, obtain medical treatment ischaemia-reperfusion slow arrhythmia Chinese medicine preparation.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510610403.2A CN105168856B (en) | 2015-09-23 | 2015-09-23 | Treat ischaemia-reperfusion slow arrhythmia Chinese medicine preparation and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510610403.2A CN105168856B (en) | 2015-09-23 | 2015-09-23 | Treat ischaemia-reperfusion slow arrhythmia Chinese medicine preparation and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105168856A CN105168856A (en) | 2015-12-23 |
| CN105168856B true CN105168856B (en) | 2018-09-07 |
Family
ID=54891606
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510610403.2A Active CN105168856B (en) | 2015-09-23 | 2015-09-23 | Treat ischaemia-reperfusion slow arrhythmia Chinese medicine preparation and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105168856B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106880826A (en) * | 2017-03-15 | 2017-06-23 | 付蓉 | A kind of Chinese medicine preparation of chronic heart failure and preparation method thereof |
| CN109490272B (en) * | 2018-12-28 | 2021-08-27 | 拉德枋斯(广东)生命科学创新研究院有限公司 | Method for observing vessel stem cell wall attachment by using middle artery |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101176751A (en) * | 2006-11-09 | 2008-05-14 | 黄振华 | Pharmaceutical composition of red sage root and cassia twig |
-
2015
- 2015-09-23 CN CN201510610403.2A patent/CN105168856B/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101176751A (en) * | 2006-11-09 | 2008-05-14 | 黄振华 | Pharmaceutical composition of red sage root and cassia twig |
Non-Patent Citations (2)
| Title |
|---|
| 益 气 复 脉 汤 治 疗 室 性 早 搏 临 床 观 察;吴玉玲等;《中国中医药现代远程教育》;20090228;第7卷(第2期);52 * |
| 益气温阳方药对大鼠心肌缺血再灌注心律失常大鼠模型SOD、MDA的影响;孙博;《中国优秀硕士学位论文全文数据库 医药卫生科技辑》;20091115(第11期);6,12,13 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN105168856A (en) | 2015-12-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103071128B (en) | Externally-applied plaster for curing dysmenorrhea | |
| CN102114231B (en) | Medicine for treating arrhythmia | |
| CN105168856B (en) | Treat ischaemia-reperfusion slow arrhythmia Chinese medicine preparation and preparation method thereof | |
| CN103479969B (en) | A kind of medicine for the treatment of manic-depressive psychosis and preparation method thereof | |
| CN103495009B (en) | Traditional Chinese medicine for treating coronary heart disease | |
| CN105055915A (en) | Traditional Chinese medicine composition for treating hypertension | |
| CN100358568C (en) | Medicine for treating high blood pressure and its preparation method | |
| CN106377621A (en) | Preparation method of traditional Chinese medicine composition for treating premature graying of beards and hair | |
| CN102526189A (en) | Chinese medicinal composition for treating angina pectoris | |
| CN102335346A (en) | Traditional Chinese medicinal preparation for treating cerebrovascular disease | |
| CN105920296A (en) | Traditional Chinese medicine preparation for adjuvant treatment of angina pectoris in qi-and-yin-deficiency type coronary heart diseases, and preparation method thereof | |
| CN104117018A (en) | Traditional Chinese medicine composition for treating coronary heart disease | |
| CN104888133A (en) | Traditional Chinese medicine composition for treatment of coronary heart disease | |
| CN101199761B (en) | Drug for treating arteriosclerosis | |
| CN104758835B (en) | A kind of Chinese medicine being used for the treatment of cerebral infarction disease | |
| CN104138565A (en) | Medicine for treating angina pectoris turbid phlegm internal stagnation type coronary heart disease | |
| CN102846910A (en) | Chinese medicine preparation for the treatment of heart premature contraction | |
| CN102836320B (en) | Chinese medicinal pill for treating tachyarrhythmia | |
| CN101322788B (en) | Chinese medicine for treating vitiligo and preparation | |
| CN106389722A (en) | Preparation method of traditional Chinese medicine for reducing white hair and gray hair | |
| CN101176743A (en) | Chinese medicine for curing coronary disease angina pectoris | |
| CN103239620B (en) | Traditional Chinese medicine for treating qi-deficiency heart diseases | |
| CN105641526A (en) | Traditional Chinese medicine for treating cardiac neurosis | |
| CN105079438A (en) | Pharmaceutic preparation for treating viral myocarditis | |
| CN104147386A (en) | Traditional Chinese medicinal preparation for treating migraine and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20190410 Address after: 450000 people's road, Jinshui District, Zhengzhou, Henan Province, No. 19 Patentee after: The First Affiliated Hospital of Henan University of traditional Chinese Medicine Address before: 450000 No. 19 Renmin Road, Zhengzhou City, Henan Province Patentee before: Gao Yuan |
|
| TR01 | Transfer of patent right |