CN105168761A - Traditional Chinese medicine treating damp-heat havoc endometritis and preparation method therefor - Google Patents

Abstract

The invention provides a traditional Chinese medicine treating damp-heat havoc endometritis and a preparation method therefor. The traditional Chinese medicine comprises raw materials: centella, calendula officinalis, smilax microphylla, astilbe chinensis, uraria crinite, root or leaf of tree beautyberry, ramie root, calamint, evolvulus alsinoides, lamium amplexicaule, starwort, marsdenia tinctoria, gelidium amansii, brassica campestris and medulla stachyuri. The traditional Chinese medicine has definite curative effects on damp-heat havoc endometritis and has low toxic and side effects, the treatment course is short and relapse is difficult.

Description

A kind ofly treat damp and hot Chinese medicine and preparation method of wreaking havoc type endometritis

Technical field

The present invention relates to the medicinal preparation containing deriving from plant, animal or mineral component, particularly relating to and a kind ofly treating damp and hot Chinese medicine and preparation method of wreaking havoc type endometritis.

Background technology

Endometritis is endometrial inflammation, is commonly encountered disease.According to the length of the course of disease, acute endometritis and chronic endometritis two kinds can be divided into.Acute inflammation likely causes the serious consequences such as diffuse peritonitis, septicemia so that septic shock.

Acute endometritis: (1) symptom: onset is comparatively anxious, have extreme aversion to cold to shiver with cold, fever (38 ~ 40 DEG C), pulse is accelerated, general weakness, and perspire, hypogastralgia is very acute, tenesmus, the soreness of waist.A large amount of courage and uprightness, purulence or water sample leucorrhea, and frowziness.Puerperal infection then lochia is earth color.(2) sign: patient's hypogastric region tenderness.The visible orifice of uterus of specula inspection have a large amount of purulence or filthy courageous and upright stink secretions excessive.During bimanual examination, cervix uteri lifts pain.Palace body swells because of congestion and edema, and soft, tenderness is obvious.Chemically examine then total white blood cells and neutrophilia.The cause of disease of acute endometritis: unhygienic, sexual intercourse in menstrual period in (1) menstrual period or sexual life disorder bring external or vagina, intracervical pathogen into uterine cavity.(2) inner membrance of low-grade infection only has hyperemia, edema, polymorphonuclear leukocyte and round cell to infiltrate.Infection is seriously then suppurated, extensive necrosis, and the muscle layer can involved under it forms acute myometritis.

Chronic endometritis: (1) symptom: 1. pelvic region pain: about have that 40% patient main suit has lower abdomen falling pain at menstruation tempus intercalare, lumbosacral region is ached.2. leucorrhoea grow in quantity: caused by inner membrance glandular secretion increases.Be generally thin water sample, faint yellow, be sanguinous leukorrhea sometimes.3. menorrhagia: menstrual period are still regular, but through amount multiplication, phase also significant prolongation of bleeding.Only a few patient is only had to cause anemia owing to bleeding in a large number, may caused by intimal thickening and inflammatory congestion.Irregular bleeding person is rare, sometimes even can hemorrhage a few hours or continue namely to stop for 1 ~ 2 day.4. dysmenorrhea: morely betide nullipara, but severe dysmenorrhea person is few, may thicken due to Excessive intimal, hinders and organizes normal regression downright bad, stimulate caused by the excessive spasmodic contraction in uterus.(2) sign: 1. mild inflammation patient, bimanual examination can situation without exception find, therefore is clinically often diagnosed as dysfunctional uterine bleeding.Someone makes pathologic diagnosis in 1000 routine dysfunctional uterine bleeding people, finds that 11% is endometritis.If 2. have pyometra, then uterus is spherical increase, soft, even above pubic symphysis, midline can lay one's hand on lump, tenderness.As secretions can be discharged by neck tube discontinuously, when specula checks, courageous and upright pus can be seen, cacosmia.Often there is acute vaginitis and deposit.The cause of disease of chronic endometritis: (1), though endometrium has periodicity to strip off, and its basal layer does not strip off thereupon, once basal layer has chronic inflammatory disease to get final product the functional layer of Long-term Infection inner membrance, causes chronic endometritis.The existence herewith mechanism of tuberculous endometritis.(2) long-standing adnexitis or serious cervicitis can cause chronic endometritis.(3) contraceptive device can cause chronic endometritis.(4) give a birth or have a small amount of Placenta remnants puerperal, or the subinvolution of Placenta Hominis facies posterior hepatis is often the reason causing chronic endometritis.(5) women after menopause, significantly low due to body inner estrogen level, endometrium and vaginal mucosa all become poor, are easily subject to the invasion and attack of pathogenic bacteria, cause the generation of inflammation.Senile endometrium is scorching with vaginitis often and deposit clinically.(6) submucosal myoma of uterus, mucosal polyp also may cause chronic endometritis.(7) chronic endometritis without obvious inducement also may exist.Pathogen is many from intravaginal flora.

Summary of the invention

Technical problem to be solved by this invention is, provide a kind of and treat damp and hot Chinese medicine and preparation method of wreaking havoc type endometritis, Chinese medicine of the present invention has definite curative effect to damp and hot type endometritis of wreaking havoc, and toxic and side effects is little.

In order to solve the problems of the technologies described above, the invention provides and a kind ofly treat damp and hot Chinese medicine of wreaking havoc type endometritis, its raw medicinal material comprises: Herba Centellae, Calendula officinalis flower, Radix Smilacis nanae, Herba Eupatorii Heterophylli, Herba Urariae crinitae, Radix seu Folium callicarpae arboreae, Radix Boehmeriae, Herba Clinopodii Polycephali, Herba Evolvuli Alsinoides, Herba Lamii Amplexicaulis, Herba stellariae mediae, Caulis Marsdeniae tinctoriae, Eucheuma gelatinosum, Caulis et Folium Brassicae campestris and Medulla Stachyuri (Medulla Helwingiae).

In described Chinese medicine, the ratio of weight and number of each raw medicinal material is as follows: Herba Centellae 10 ~ 20 parts, and Calendula officinalis spends 8 ~ 18 parts, Radix Smilacis nanae 20 ~ 30 parts, Herba Eupatorii Heterophylli 10 ~ 20 parts, Herba Urariae crinitae 5 ~ 15 parts, Radix seu Folium callicarpae arboreae 20 ~ 30 parts, Radix Boehmeriae 20 ~ 30 parts, Herba Clinopodii Polycephali 28 ~ 38 parts, 15 ~ 25 parts, Herba Evolvuli Alsinoides, Herba Lamii Amplexicaulis 20 ~ 30 parts, Herba stellariae mediae 10 ~ 20 parts, Caulis Marsdeniae tinctoriae 22 ~ 32 parts, Eucheuma gelatinosum 15 ~ 25 parts, Caulis et Folium Brassicae campestris 23 ~ 33 parts and Medulla Stachyuri (Medulla Helwingiae) 10 ~ 20 parts.

In described Chinese medicine, the ratio of weight and number of each raw medicinal material can be preferably: Herba Centellae 15 ~ 20 parts, and Calendula officinalis spends 10 ~ 15 parts, Radix Smilacis nanae 22 ~ 27 parts, Herba Eupatorii Heterophylli 13 ~ 18 parts, Herba Urariae crinitae 8 ~ 13 parts, Radix seu Folium callicarpae arboreae 25 ~ 30 parts, Radix Boehmeriae 20 ~ 25 parts, Herba Clinopodii Polycephali 30 ~ 35 parts, 17 ~ 22 parts, Herba Evolvuli Alsinoides, Herba Lamii Amplexicaulis 23 ~ 28 parts, Herba stellariae mediae 12 ~ 17 parts, Caulis Marsdeniae tinctoriae 24 ~ 29 parts, Eucheuma gelatinosum 17 ~ 22 parts, Caulis et Folium Brassicae campestris 25 ~ 30 parts and Medulla Stachyuri (Medulla Helwingiae) 13 ~ 18 parts.

In described Chinese medicine, the ratio of weight and number of each raw medicinal material also can be preferably: Herba Centellae 18 parts, and Calendula officinalis spends 12 parts, Radix Smilacis nanae 26 parts, Herba Eupatorii Heterophylli 14 parts, Herba Urariae crinitae 12 parts, Radix seu Folium callicarpae arboreae 27 parts, Radix Boehmeriae 24 parts, Herba Clinopodii Polycephali 32 parts, 20 parts, Herba Evolvuli Alsinoides, Herba Lamii Amplexicaulis 24 parts, Herba stellariae mediae 16 parts, Caulis Marsdeniae tinctoriae 25 parts, Eucheuma gelatinosum 21 parts, Caulis et Folium Brassicae campestris 26 parts and Medulla Stachyuri (Medulla Helwingiae) 17 parts.

In described Chinese medicine, the ratio of weight and number of each raw medicinal material also can be preferably: Herba Centellae 16 parts, and Calendula officinalis spends 14 parts, Radix Smilacis nanae 23 parts, Herba Eupatorii Heterophylli 16 parts, Herba Urariae crinitae 10 parts, Radix seu Folium callicarpae arboreae 28 parts, Radix Boehmeriae 22 parts, Herba Clinopodii Polycephali 33 parts, 18 parts, Herba Evolvuli Alsinoides, Herba Lamii Amplexicaulis 26 parts, Herba stellariae mediae 14 parts, Caulis Marsdeniae tinctoriae 28 parts, Eucheuma gelatinosum 18 parts, Caulis et Folium Brassicae campestris 28 parts and Medulla Stachyuri (Medulla Helwingiae) 15 parts.

Present invention also offers the preparation method of above-mentioned Chinese medicine, the dosage form of described Chinese medicine is capsule, and its preparation method comprises the following steps:

The first step, is mixed in proportion each for described Chinese medicine raw medicinal material, and adding relative to the determining alcohol of mixture quality 2 ~ 4 times is the ethanol of 85 ~ 95%, reflux 1 ~ 3 hour, extracts, and filters acquisition first extracting solution; It is the ethanol of 85 ~ 95% that the medicinal residues that filtration obtains add relative to the determining alcohol of described medicinal residues quality 1 ~ 2 times again, reflux 1 ~ 3 hour, extracts, and filters acquisition second extracting solution; First extracting solution and the second extracting solution are merged, concentrating under reduced pressure removing alcohol solvent, dry, obtain and get dry extract;

Second step, is placed on the dry cream that the first step obtains in super micron mill and pulverizes 1 ~ 2 hour, pulverize, sieve, obtain 300 order ~ 400 object micropowders;

3rd step, adds Pulvis Talci, magnesium stearate successively in the micropowders that second step obtains, and carries out mixing process, obtains capsule 's content; Described micropowders, magnesium stearate and talcous weight ratio are 100: 0.15 ~ 0.5:0.15 ~ 0.5, incapsulate in housing by described capsule 's content, obtain capsule finished product.

Present invention also offers the preparation method of above-mentioned Chinese medicine, the dosage form of described Chinese medicine is powder, and its preparation method comprises the following steps:

The first step, is mixed in proportion described raw medicinal material, is ground into powder;

Second step, the first step is obtained powder and add in cold water and soak 6 hours ~ 12 hours, with slow fire boiling, decocting time is 3 hours ~ 5 hours, decoction liquor is filtered, obtains the first filtrate, and the quality of the water added is 2 ~ 4 times of the powder quality that the first step obtains;

3rd step, filters second step the filtering residue obtained and again adds in cold water, with slow fire boiling 2 hours ~ 4 hours, filters acquisition second filtrate, and the quality of the water added is 2 ~ 4 times of the powder quality that second step obtains;

4th step, the second filtrate mixing that the first filtrate obtain second step and the 3rd step obtain, concentrating under reduced pressure, except anhydrating, dry, pulverize powdered, and granularity is 80 ~ 120 orders;

5th step, in the powder that described 4th step obtains, add starch, the percentage by weight of described starch in described powder is 15% ~ 30%, and by the material pouch after mixing or packing box subpackage, every 5 ~ 10 grams is one bag or a box subpackage.

Beneficial effect of the present invention: Chinese medicine of the present invention has definite curative effect to damp and hot type endometritis of wreaking havoc, and toxic and side effects is little, short treating period, not easily recurs.

Detailed description of the invention

The invention provides and a kind ofly treat damp and hot Chinese medicine of wreaking havoc type endometritis, its raw medicinal material comprises: Herba Centellae, Calendula officinalis flower, Radix Smilacis nanae, Herba Eupatorii Heterophylli, Herba Urariae crinitae, Radix seu Folium callicarpae arboreae, Radix Boehmeriae, Herba Clinopodii Polycephali, Herba Evolvuli Alsinoides, Herba Lamii Amplexicaulis, Herba stellariae mediae, Caulis Marsdeniae tinctoriae, Eucheuma gelatinosum, Caulis et Folium Brassicae campestris and Medulla Stachyuri (Medulla Helwingiae).

In described Chinese medicine, the pharmacology of each raw medicinal material is as follows:

Herba Centellae: [another name] Herba Glechomae, marchantia grass, Herba Calthae Membranaceae, Gotu Kola, certain herbaceous plants with big flowers Penglai, chipping bowl, Herba sambuci chinensis, Chinese bush cherry grass, large Herba Calthae Membranaceae, TUXIXIN, collapse jorum, Gotu Kola, the Congo dragon, Herba Centellae taro grass, something that gives the game away mark, bud Dendrobium denneanum Kerr., careless as one wishes, Carnis Arca inflata shell is careless, determine containing shell grass, bowl of begging for food, old jackal bowl, flood money, Hydrocotyle sibthorpioides lam.Var.Batvachium (Hand.-Mazz.) et shan. grass, Hydrocotyle vulgaris L., old duck, bowl is broken in ferrum oil lamp, half of bowl, Herba speranskiae tuberculatae, jumping, Thunder God bowl, Herba Asari, Herba lysimachiae capillipedis.[source] medical material Ji Yuan: be the herb of samphire Herba Centellae.[nature and flavor] bitter in the mouth; Pungent; Cold in nature.[return through] returns lung; Spleen; Kidney; Urinary bladder channel.[function cures mainly] clearing away heat-damp and promoting diuresis; Promoting blood circulation and hemostasis; Removing toxic substances and promoting subsidence of swelling.Main heating; Cough with asthma; Laryngopharynx swelling and pain; Dysentery; Jaundice due to damp-heat; Edema; Stranguria; Hematuria; Epistaxis; Dysmenorrhea; Metrorrhagia; Erysipelas; Scrofula; Parent's pyogenic infections from tumour or sore; Herpes zoster; Treating swelling and pain by traumatic injury; Traumatic hemorrhage; Snake bite and insect sting.[extracts] " China's book on Chinese herbal medicine "

Calendula officinalis flower: [source] medical material Ji Yuan: be the flower of feverfew Calendula officinalis.Latin plant animal mineral name: CalendulaOfficinalisL.Gather and store: spring, summer gather, using fresh herb or dry in the shade.[nature and flavor] are lightly seasoned; Property is put down.[function cures mainly] cooling blood for hemostasis; Clearing away heat-fire.Main discharging fresh blood stool; Conjunctival congestion and swelling pain.[extracts] " China's book on Chinese herbal medicine "

Radix Smilacis nanae: [another name] Ci Suoluo, Rhizoma Smilacis microphyllae.[source] medical material Ji Yuan: be the root of liliaceous plant lobule Rhizoma Smilacis Chinensis.Latin plant animal mineral name: SmilaxmicrophyllaC.H.Wright.[nature and flavor] toil; Cool.[function cures mainly] dispels the wind; Heat clearing away; Dampness removing.Main air damp-heat arthralgia; Hot urination; Leucorrhea; Furuncle.[extracts] " China's book on Chinese herbal medicine "

Herba Eupatorii Heterophylli: [another name] Huang Lihua, Rhizoma seu Herba Elatostematis stewardii, Herba Lycopi, little Rhizoma Cimicifugae, golden hair Radix Notoginseng, the pellet that helps digestion, three angular bits, water Rhizoma Cimicifugae, Rhizoma Schizocapsae Plantagineae, Cibotium barometz (L.) J. Sm., black sufficient Rhizoma Cimicifugae.[source] medical material Ji Yuan: be the rhizome of saxifragaceae plant Herba astilbes chinensis and large Herba astilbes chinensis.[nature and flavor] acrid in the mouth, hardship, warm in nature.[return through] Liver Channel.[function cures mainly] promoting blood circulation and stopping pain, expelling wind and removing dampness, strengthening the tendons and bones, removing toxic substances.Main amenorrhea; Lump in the abdomen; Traumatic injury; Orchitis; Venom.[extracts] " China's book on Chinese herbal medicine " " Chinese medicine voluminous dictionary "

Herba Urariae crinitae: [another name] Herba Urariae Lagopodioidis, timothy grass, tiger tail, system sky grass, university degree mountain green grass or young crops, ancient coin window grass, the golden mace of ferrum, Canis familiaris L. tail are penetrated.[source] medical material Ji Yuan: the herb penetrated for leguminous plant cat tail.[nature and flavor] are sweet; Micro-hardship; Flat.[return through] heart; Lung; Liver Channel.[function cures mainly] clearing away lung-heat to relieve cough; Dissipating blood stasis stops blooding.Main cough due to lung-heat; Lung abscess; Gather; Acute mastitis; Proctoptosis; Uterine prolapse; Spit blood; Hematuria; Traumatic hemorrhage.[extracts] " China's book on Chinese herbal medicine "

Radix seu Folium callicarpae arboreae: [another name] Folium Callicarpae Formosanae, greatly set Folium Callicarpae Formosanae, Lindera playfairii tree.[source] medical material Ji Yuan: be root, the leaf of dicotyledon medicine Verbenaceae Nan Yang Folium Callicarpae Formosanae.[nature and flavor] micro-bitterness; Flat.[return through] Liver Channel.[function cures mainly] astringing to arrest bleeding; Heat-clearing and toxic substances removing.Main epistaxis; Spitting of blood; Gastrointestinal hemorrhage; Woman uterine bleeding; Laryngopharynx swelling and pain; Traumatic hemorrhage; Burn.[extracts] " China's book on Chinese herbal medicine "

Radix Boehmeriae: [another name] ramie root, wild ramie root, Boehmeria are eaten.[source] medical material Ji Yuan: be the root welding technology of contrayerva Boehmeria.[nature and flavor] are sweet; Cold in nature.[return through] liver; The heart; Urinary bladder channel.[function cures mainly] cooling blood for hemostasis; Clearing heat and preventing abortion; Diuresis; Removing toxic substances.Spitting of blood caused by main bleeding due to blood-heat; Spit blood; Epistaxis; Stranguria with blood; Have blood in stool; Metrorrhagia; Purpura; Frequent fetal movement; Vaginal bleeding during pregnancy hematochezia; Dribbling urination; Carbuncle pyogenic infections from tumour or sore; Worm venom.[extracts] " China's book on Chinese herbal medicine "

Herba Clinopodii Polycephali: [another name] Herba leucadis zeylanicae, Herba Clinopodii Polycephali, JIUCENGTA, Herba Elephantopi scaberis, bear gall grass, nine towers grass, land Flos Mume, Herba Clinopodii, bitter cutter grass.[source] medical material Ji Yuan: be the herb of labiate Herba Clinopodii Polycephali.[nature and flavor] acrid in the mouth; Bitter; Cool in nature.[function cures mainly] wind and heat dispersing; Removing toxic substances and promoting subsidence of swelling; Hemostasis.Main cold, fever; Heatstroke; Laryngopharynx swelling and pain; Diphtheria; Acute cholecystitis; Hepatitis; Intestinal is scorching; Dysentery is scorching; Dysentery; Rib adenitis; Mastitis; Furuncle swelling toxin; Allergic dermatitis; Acute conjunctivitis; Hematuria; Metrorrhagia; Gingival hemorrhage; Traumatic hemorrhage.[extracts] " China's book on Chinese herbal medicine "

Herba Evolvuli Alsinoides: the peppery flower of [another name] hair, filamentary silver grass, careless, the fawn rank of starvation, Herba Pyrolae, small capital Pemisetum flaccidum Griseb, heath bell, dysentery grass, Flos Lonicerae are careless, radix euphorbiae, Herba Stenosolenii saxatilis, Bai Maolian, white hair general, pigeon grass, Bai Toumei, sudden and violent smelly Serpentis, ree-oil be colored.[source] medical material Ji Yuan: be the herb of dicotyledon scammonia section plant Herba Evolvuli Alsinoides.Latin plant animal mineral name: EvolvulusalsinoidesL.[nature and flavor] sweetness and bitterness; Cool.[return through] liver; Spleen; Kidney channel.[function cures mainly] heat clearing away; Dampness removing; Removing toxic substances.Main jaundice; Dysentery; Stranguria with turbid discharge; Leukorrhagia; Treat swollen; Scabies.[extracts] " China's book on Chinese herbal medicine "

Herba Lamii Amplexicaulis: [another name] Rhizoma seu Herba Elatostematis stewardii, the lotus throne summer is withered, Mao Yexia is withered, the imperial grass of lamp, Radix Thalictri Trichopi, Buddhist seat, wind small cup, Herba Glechomae, large copper coin seven, wax candle skewer grass.[source] medical material Ji Yuan: be the herb of labiate Herba Lamii Amplexicaulis.[nature and flavor] acrid in the mouth; Bitter; Slightly warm in nature.[function cures mainly] promoting blood circulation to remove obstruction in the collateral; Removing toxic substances and promoting subsidence of swelling.Main traumatic injury; Bones and muscles pain; Numb limbs and tense tendons; Hemiplegia; Face is completed; Jaundice; Nasal sinusitis; Scrofula; Toxic swelling; Impetigo.[extracts] " China's book on Chinese herbal medicine "

Herba stellariae mediae: [another name] numerous beach wormwood, taste grass, Herba malachii aquatici, goose intestinal dish, Herba Ipomoeae Cairicae, dog flea dish, goose wonton, circle sauerkraut, wild black dish, Adenocaulon himalaicum Edgew Maxim, black clouds grass.[source] medical material Ji Yuan: be the herb of pinkwort Herba stellariae mediae.[nature and flavor] micro-hardship; Sweet; Acid; Cool in nature.[return through] liver; Large intestine channel.[function cures mainly] heat-clearing and toxic substances removing; Removing heat from blood eliminating carbuncle; Promoting blood circulation and stopping pain; Stimulating milk secretion.Main dysentery; Intestinal carbuncle; Lung abscess; Acute mastitis; Furuncle swelling toxin; Swelling and pain of hemorrhoid; Hemorrhage; Traumatic pain; The stagnant stomachache of the stasis of blood in puerperal; Agalactia.[extracts] " China's book on Chinese herbal medicine "

Caulis Marsdeniae tinctoriae: [another name] Xiao the ears of an ox or cow rattan, swordweed, dyeing Marsdenia, crow mouth.[source] medical material Ji Yuan: be the fruit of dicotyledon medicine asclepiadaceae plant Caulis Marsdeniae tinctoriae.[nature and flavor] acrid in the mouth, hardship, warm in nature.[return through] liver, stomach two warp.[function cures mainly] expelling wind and removing dampness; Blood stasis-eliminating and stagnation-dissipating.Main rheumatic ostalgia; Hepatomegaly.[each discussion] " Xinhua's book on Chinese herbal medicine outline ": really: control heart peratodynia.[extracts] " China's book on Chinese herbal medicine "

Eucheuma gelatinosum: [another name] Eucheuma gelatinosum, ox hair Parmelia saxatilis Ach., Parmelia saxatilis Ach. grass, freeze dish, red filament, snowflake dish, ox hair dish, Eucheuma gelatinosum, phoenix tail, onyx, Ottelia acuminata (Gagnep.) Dandy, Herba Pileae Scriptae.[source] medical material Ji Yuan: be the frond of Gelidiaceae phytobezoar Herba Astragali Sinici, fine, soft fur Eucheuma gelatinosum, pacific gelidium etc.[nature and flavor] are sweet; Salty; Cold; Sliding; Nontoxic.[return through] liver; Lung meridian.[function cures mainly] heat-clearing and toxic substances removing; Blood stasis-eliminating and stagnation-dissipating; Laxation; Drive ascarid.Main enteritis, diarrhea; Pyelonephritis; Goiter; Tumor; Bleeding hemorrhoids; Chronic constipation; Ascarid is disease early.[extracts] " China's book on Chinese herbal medicine " " Chinese medicine voluminous dictionary "

Caulis et Folium Brassicae campestris: [another name] Caulis et Folium Brassicae campestris, cold dish, a kind of sedge dish, Caulis et Folium Brassicae campestris dish, a kind of sedge mustard, green vegetable, chilli oil dish.[source] medical material Ji Yuan: be the root of crucifer Brassica campestris L, stem and leaf.[nature and flavor] are pungent; Sweet; Property is put down.[return through] lung; Liver; Spleen channel.[function cures mainly] removing pathogenic heat from blood and dissipating blood stasis; Removing toxic substances and promoting subsidence of swelling.Main dysentery; Erysipelas; Hot carbuncle toxin; Acute mastitis; Rubella; Spit blood.[extracts] " China's book on Chinese herbal medicine "

Medulla Stachyuri (Medulla Helwingiae): [another name] little logical flower, fish bubble is logical, Himalaya ancient type of banner hoisted on a featherdecked mast joint is spent, Medulla Tetrapanacis is set, poker tree.[source] medical material Ji Yuan: be the stem pith of Stachyuraceae plant Himalaya ancient type of banner hoisted on a featherdecked mast joint flower, Chinese ancient type of banner hoisted on a featherdecked mast joint flower, Acanthopanax obovatus Hoo ancient type of banner hoisted on a featherdecked mast joint flower, Folium Salicis Babylonicae ancient type of banner hoisted on a featherdecked mast joint flower, Sichuan ancient type of banner hoisted on a featherdecked mast joint flower, Yunnan ancient type of banner hoisted on a featherdecked mast joint flower.[nature and flavor] sweet in the mouth; Light; Cool in nature; Return lung; Stomach; Urinary bladder channel.[return through] lung; Stomach warp.[function cures mainly] heat clearing away; Diuretic; Lactogenesis.Main calentura excessive thirst, yellowish or reddish urine, oliguria or urine retention, acute cystitis; Nephritis; Edema; Dysuria; Galactostasis.[extracts] " China's book on Chinese herbal medicine "

In described Chinese medicine, the ratio of weight and number of each raw medicinal material is as follows: Herba Centellae 10 ~ 20 parts, and Calendula officinalis spends 8 ~ 18 parts, Radix Smilacis nanae 20 ~ 30 parts, Herba Eupatorii Heterophylli 10 ~ 20 parts, Herba Urariae crinitae 5 ~ 15 parts, Radix seu Folium callicarpae arboreae 20 ~ 30 parts, Radix Boehmeriae 20 ~ 30 parts, Herba Clinopodii Polycephali 28 ~ 38 parts, 15 ~ 25 parts, Herba Evolvuli Alsinoides, Herba Lamii Amplexicaulis 20 ~ 30 parts, Herba stellariae mediae 10 ~ 20 parts, Caulis Marsdeniae tinctoriae 22 ~ 32 parts, Eucheuma gelatinosum 15 ~ 25 parts, Caulis et Folium Brassicae campestris 23 ~ 33 parts and Medulla Stachyuri (Medulla Helwingiae) 10 ~ 20 parts.

In described Chinese medicine, the ratio of weight and number of each raw medicinal material can be preferably: Herba Centellae 15 ~ 20 parts, and Calendula officinalis spends 10 ~ 15 parts, Radix Smilacis nanae 22 ~ 27 parts, Herba Eupatorii Heterophylli 13 ~ 18 parts, Herba Urariae crinitae 8 ~ 13 parts, Radix seu Folium callicarpae arboreae 25 ~ 30 parts, Radix Boehmeriae 20 ~ 25 parts, Herba Clinopodii Polycephali 30 ~ 35 parts, 17 ~ 22 parts, Herba Evolvuli Alsinoides, Herba Lamii Amplexicaulis 23 ~ 28 parts, Herba stellariae mediae 12 ~ 17 parts, Caulis Marsdeniae tinctoriae 24 ~ 29 parts, Eucheuma gelatinosum 17 ~ 22 parts, Caulis et Folium Brassicae campestris 25 ~ 30 parts and Medulla Stachyuri (Medulla Helwingiae) 13 ~ 18 parts.

In described Chinese medicine, the ratio of weight and number of each raw medicinal material also can be preferably: Herba Centellae 18 parts, and Calendula officinalis spends 12 parts, Radix Smilacis nanae 26 parts, Herba Eupatorii Heterophylli 14 parts, Herba Urariae crinitae 12 parts, Radix seu Folium callicarpae arboreae 27 parts, Radix Boehmeriae 24 parts, Herba Clinopodii Polycephali 32 parts, 20 parts, Herba Evolvuli Alsinoides, Herba Lamii Amplexicaulis 24 parts, Herba stellariae mediae 16 parts, Caulis Marsdeniae tinctoriae 25 parts, Eucheuma gelatinosum 21 parts, Caulis et Folium Brassicae campestris 26 parts and Medulla Stachyuri (Medulla Helwingiae) 17 parts.

In described Chinese medicine, the ratio of weight and number of each raw medicinal material also can be preferably: Herba Centellae 16 parts, and Calendula officinalis spends 14 parts, Radix Smilacis nanae 23 parts, Herba Eupatorii Heterophylli 16 parts, Herba Urariae crinitae 10 parts, Radix seu Folium callicarpae arboreae 28 parts, Radix Boehmeriae 22 parts, Herba Clinopodii Polycephali 33 parts, 18 parts, Herba Evolvuli Alsinoides, Herba Lamii Amplexicaulis 26 parts, Herba stellariae mediae 14 parts, Caulis Marsdeniae tinctoriae 28 parts, Eucheuma gelatinosum 18 parts, Caulis et Folium Brassicae campestris 28 parts and Medulla Stachyuri (Medulla Helwingiae) 15 parts.

Present invention also offers the preparation method of above-mentioned Chinese medicine, the dosage form of described Chinese medicine is capsule, and its preparation method comprises the following steps:

The first step, is mixed in proportion each for described Chinese medicine raw medicinal material, and adding relative to the determining alcohol of mixture quality 2 ~ 4 times is the ethanol of 85 ~ 95%, reflux 1 ~ 3 hour, extracts, and filters acquisition first extracting solution; It is the ethanol of 85 ~ 95% that the medicinal residues that filtration obtains add relative to the determining alcohol of described medicinal residues quality 1 ~ 2 times again, reflux 1 ~ 3 hour, extracts, and filters acquisition second extracting solution; First extracting solution and the second extracting solution are merged, concentrating under reduced pressure removing alcohol solvent, dry, obtain and get dry extract;

Second step, is placed on the dry cream that the first step obtains in super micron mill and pulverizes 1 ~ 2 hour, pulverize, sieve, obtain 300 order ~ 400 object micropowders;

3rd step, adds Pulvis Talci, magnesium stearate successively in the micropowders that second step obtains, and carries out mixing process, obtains capsule 's content; Described micropowders, magnesium stearate and talcous weight ratio are 100: 0.15 ~ 0.5:0.15 ~ 0.5, incapsulate in housing by described capsule 's content, obtain capsule finished product.

Present invention also offers the preparation method of above-mentioned Chinese medicine, the dosage form of described Chinese medicine is powder, and its preparation method comprises the following steps:

The first step, is mixed in proportion described raw medicinal material, is ground into powder;

Second step, the first step is obtained powder and add in cold water and soak 6 hours ~ 12 hours, with slow fire boiling, decocting time is 3 hours ~ 5 hours, decoction liquor is filtered, obtains the first filtrate, and the quality of the water added is 2 ~ 4 times of the powder quality that the first step obtains;

3rd step, filters second step the filtering residue obtained and again adds in cold water, with slow fire boiling 2 hours ~ 4 hours, filters acquisition second filtrate, and the quality of the water added is 2 ~ 4 times of the powder quality that second step obtains;

4th step, the second filtrate mixing that the first filtrate obtain second step and the 3rd step obtain, concentrating under reduced pressure, except anhydrating, dry, pulverize powdered, and granularity is 80 ~ 120 orders;

5th step, in the powder that described 4th step obtains, add starch, the percentage by weight of described starch in described powder is 15% ~ 30%, and by the material pouch after mixing or packing box subpackage, every 5 ~ 10 grams is one bag or a box subpackage.

Below adopt embodiment to describe embodiments of the present invention in detail, fully understand how application technology means solve technical problem in the present invention whereby, reach technique effect and implement according to this.

Embodiment 1: capsule

Get Herba Centellae 160g, Calendula officinalis flower 140g, Radix Smilacis nanae 230g, Herba Eupatorii Heterophylli 160g, Herba Urariae crinitae 100g, Radix seu Folium callicarpae arboreae 280g, Radix Boehmeriae 220g, Herba Clinopodii Polycephali 330g, Herba Evolvuli Alsinoides 180g, Herba Lamii Amplexicaulis 260g, Herba stellariae mediae 140g, Caulis Marsdeniae tinctoriae 280g, Eucheuma gelatinosum 180g, Caulis et Folium Brassicae campestris 280g and Medulla Stachyuri (Medulla Helwingiae) 150g;

Prepare according to the following steps:

The first step, is mixed in proportion each for described Chinese medicine raw medicinal material, and adding relative to the determining alcohol of mixture quality 4 times is the ethanol of 85%, reflux 2 hours, extracts, and filters acquisition first extracting solution; It is the ethanol of 95% that the medicinal residues that filtration obtains add relative to the determining alcohol of described medicinal residues quality 2 times again, reflux 3 hours, extracts, and filters acquisition second extracting solution; First extracting solution and the second extracting solution are merged, concentrating under reduced pressure removing alcohol solvent, dry, obtain and get dry extract;

Second step, is placed on the dry cream that the first step obtains in super micron mill and pulverizes 2 hours, pulverize, sieve, obtain 400 object micropowders;

3rd step, adds Pulvis Talci, magnesium stearate successively in the micropowders that second step obtains, and carries out mixing process, obtains capsule 's content; Described micropowders, magnesium stearate and talcous weight ratio are 100: 0.2:0.3, incapsulate in housing by described capsule 's content, obtain capsule finished product.

Embodiment 2: powder

Get Herba Centellae 180g, Calendula officinalis flower 120g, Radix Smilacis nanae 260g, Herba Eupatorii Heterophylli 140g, Herba Urariae crinitae 120g, Radix seu Folium callicarpae arboreae 270g, Radix Boehmeriae 240g, Herba Clinopodii Polycephali 320g, Herba Evolvuli Alsinoides 200g, Herba Lamii Amplexicaulis 240g, Herba stellariae mediae 160g, Caulis Marsdeniae tinctoriae 250g, Eucheuma gelatinosum 210g, Caulis et Folium Brassicae campestris 260g and Medulla Stachyuri (Medulla Helwingiae) 170g;

Prepare according to the following steps:

The first step, is mixed in proportion described raw medicinal material, is ground into powder;

Second step, the first step is obtained powder and add in cold water and soak 8 hours, with slow fire boiling, decocting time is 4 hours, decoction liquor is filtered, obtains the first filtrate, and the quality of the water added is 3 times of the powder quality that the first step obtains;

3rd step, filters second step the filtering residue obtained and again adds in cold water, with slow fire boiling 4 hours, filters acquisition second filtrate, and the quality of the water added is 3 times of the powder quality that second step obtains;

4th step, the second filtrate mixing that the first filtrate obtain second step and the 3rd step obtain, concentrating under reduced pressure, except anhydrating, dry, pulverize powdered, and granularity is 100 orders;

5th step, in the powder that described 4th step obtains, add starch, the percentage by weight of described starch in described powder is 20%, and by the material pouch subpackage after mixing, every 10 grams is one bag of subpackage.

Toxicity test:

Acute toxicity testing: application mice 60, male and female half and half, body weight 20-34g, carries out acute toxicity test.Mice is divided into two groups at random, i.e. matched group and administration group, before experiment, fasting 12 hours, is dissolved in water by Chinese medicine capsules prepared by embodiments of the invention 1, (concentration is 7.98g crude drug/ml, maximum concentration) gavage, gavage volume is 5ml/kg (namely unit dosage form is 39.9 crude drugs/kg), and matched group gives normal saline, administration in one day 2 times, delivery time 6 hours, Continuous Observation 14 days after administration, and record mice toxic reaction and death toll.Experimental result shows: compare with matched group, and after administration, mice has no notable difference, and experiment Continuous Observation 14 days, mouse systemic situation, diet, drinking-water, body weight increase all normal.Mouse oral gavage capsule LD50>39.9 crude drug/kg of the present invention, every day, maximum dosage-feeding was 79.8 crude drugs/kg/ day.Chinese medicine clinical application amount of the present invention be 8.0g crude drug/day/people, adult body weight in 60KG, average dosage is 0.133g crude drug/kg/ day.By weighing machine: the dosis tolerata of mice (average weight is in 27g) oral administration gavage Chinese medicine of the present invention is 600 times of quantity.Therefore Chinese medicine acute toxicity of the present invention is extremely low, clinical drug safety.

Long term toxicity test: Chinese medicine embodiment 1 capsule of the present invention presses 14.24,20.66 and 40.87g crude drug/kg continuous use 15 weeks (1.0ml/100g body weight to mice, every day 2 times) and drug withdrawal after 3 weeks, result shows: the index such as hair, behavior, defecation, body weight, organ weights, hemogram, hepatic and renal function, blood glucose, blood fat of Chinese medicine of the present invention to mice all has no significant effect, internal organs naked eyes do not find that difference change and histological indications show, medication 15 weeks and drug withdrawal are after 3 weeks, and Organs of Mice is all without obviously changing.Illustrate that Chinese medicine of the present invention is little to toxicity after mice long-term prescription, also there is no difference reaction after drug withdrawal, application safety.

Clinical data:

Case selection: whole 88 routine cases are my Out-patient Department patient of in July, 2012 ~ 2014 year October.Patient is divided into treatment group and matched group at random, wherein treatment group 48 people, 23 ~ 49 years old age, the course of disease 3 days ~ 4 years; Acute endometritis 18 example, chronic endometritis 30 example.Matched group 40 people, 28 ~ 53 years old age, the course of disease 4 days ~ 4 years; Acute endometritis 15 example, chronic endometritis 25 example.Two groups in age, the course of disease, symptom, coincident with severity degree of condition and laboratory checking index etc. through statistical analysis there was no significant difference (p>0.05).

Diagnostic criteria:

Western medicine diagnose standard: 1, unexpected hypogastralgia, or often lower abdomen dull pain and falling inflation sense.2, waist and sacrum pain, leucorrhoea grow in quantity yellow skin has taste.3, generate heat, body temperature 38 ~ 40 DEG C, pulse speeds to 120 ~ 140 times/min.4, cervical orifice has a large amount of purulent secretion excessive.5, cervix uteri lifts pain, and body of uterus increases tenderness.6, irregular vagina bleeding or menostaxis, dysmenorrhea, amenorrhea is had.7, lab testing: leukocyte raises, middle granulocyte is more than 0.80, and cervical secretions is cultivated has pathogenic bacterium to grow.

Tcm syndrome differentiation and typing: damp and hotly wreak havoc type: leucorrhea with yellow discharge amount is how smelly dirty, lower abdomen pendant pain or tenderness, can accompany waist and sacrum pain, or lower abdominal distention pain, or extremity dysphoria with smothery sensation, or oliguria, or it is not well etc. to defecate, bitter taste greasy taste in the mouth, red tongue, yellow and greasy fur or thick, slippery and rapid pulse.

Therapeutic Method:

Matched group: 5% glucose injection adds Radix Salviae Miltiorrhizae Injection 20ml, metronidazole liquid 500ml.Quiet once a day.A course for the treatment of one Monday, be used in conjunction four courses for the treatment of.

Treatment group: treatment group: give the embodiment of the present invention 1 capsule, every day 3 times, each 4.It within one week, was 1 course for the treatment of, continuously with four courses for the treatment of.

Curative effect judging standard: cure: menstruation recovery is normal, and vaginal secretions increases transference cure, ultrasound diagnosis finds that the congested adhesion of endometrium and inflammatory reaction disappear, and patient uterine's inner membrance suitably thickens.Effective: menstruation recovery is better, and vaginal secretions obviously reduces, and congested adhesion and inflammatory reaction take a turn for the better.Invalid: clinical symptoms is unchanged and worsen.

Therapeutic outcome: in table 1 and table 2.

A table 1 liang group patient total effects compares:

Group	n	Cure	Effectively	Invalid	Effectively total
						Treatment group	48	30	15	3	45(93.8％)
Matched group	40	17	16	7	33(82.5％)

Known by table 1, treatment group curative effect is better than matched group.

A table 2 liang group is cured patient and is compared onset time:

Group	n	Medication 1 week	Medication 2 weeks	Medication 3 weeks	Medication 4 weeks
						Treatment group	30	5(10.4％)	12(25％)	21(43.8％)	30(62.5％)
Matched group	17	2(5％)	6(15％)	12(30％)	17(42.5％)

Known by table 2, treatment group onset time is obviously better than matched group.

Two groups of relapse rates compare: choose treatment group and matched group and cure case and follow up a case by regular visits to half a year respectively and carry out relapse rate, treatment group 30 example, have 0 people's recurrence, relapse rate is 0; Matched group has 3 people's recurrences, and relapse rate is 17.6% (3/17); Difference has statistical significance (p<0.05), and treatment group relapse rate is starkly lower than matched group.

Concrete case: high certain, women, 38 years old, see a doctor because the symptoms such as unexpected hypogastralgia enter other hospitals, be diagnosed as acute endometritis, after treating one week, effect was undesirable, sees a doctor to my institute.Disease sees that leucorrhea with yellow discharge amount is how smelly dirty, lower abdomen pendant pain, waist and sacrum pain, and extremity dysphoria with smothery sensation, defecates not well, bitter taste greasy taste in the mouth, red tongue, thick fur, slippery and rapid pulse, in conjunction with other gynecologial examinations, is diagnosed as and damp and hotly wreaks havoc type acute endometritis.Give Chinese medicine embodiment 1 capsule of the present invention, each 4, every day 3 times, treat healing in 1 week, follow up a case by regular visits to and do not recur half a year.

Claims (9)

1. treat a damp and hot Chinese medicine of wreaking havoc type endometritis, it is characterized in that, each raw medicinal material of described Chinese medicine comprises: Herba Centellae, Calendula officinalis flower, Radix Smilacis nanae, Herba Eupatorii Heterophylli, Herba Urariae crinitae, Radix seu Folium callicarpae arboreae, Radix Boehmeriae, Herba Clinopodii Polycephali, Herba Evolvuli Alsinoides, Herba Lamii Amplexicaulis, Herba stellariae mediae, Caulis Marsdeniae tinctoriae, Eucheuma gelatinosum, Caulis et Folium Brassicae campestris and Medulla Stachyuri (Medulla Helwingiae).

2. Chinese medicine as claimed in claim 1, it is characterized in that, the ratio of weight and number of each raw medicinal material of described Chinese medicine is as follows: Herba Centellae 10 ~ 20 parts, Calendula officinalis spends 8 ~ 18 parts, Radix Smilacis nanae 20 ~ 30 parts, Herba Eupatorii Heterophylli 10 ~ 20 parts, Herba Urariae crinitae 5 ~ 15 parts, Radix seu Folium callicarpae arboreae 20 ~ 30 parts, Radix Boehmeriae 20 ~ 30 parts, Herba Clinopodii Polycephali 28 ~ 38 parts, 15 ~ 25 parts, Herba Evolvuli Alsinoides, Herba Lamii Amplexicaulis 20 ~ 30 parts, Herba stellariae mediae 10 ~ 20 parts, Caulis Marsdeniae tinctoriae 22 ~ 32 parts, Eucheuma gelatinosum 15 ~ 25 parts, Caulis et Folium Brassicae campestris 23 ~ 33 parts and Medulla Stachyuri (Medulla Helwingiae) 10 ~ 20 parts.

3. Chinese medicine as claimed in claim 1 or 2, it is characterized in that, the ratio of weight and number of each raw medicinal material of described Chinese medicine is as follows: Herba Centellae 15 ~ 20 parts, Calendula officinalis spends 10 ~ 15 parts, Radix Smilacis nanae 22 ~ 27 parts, Herba Eupatorii Heterophylli 13 ~ 18 parts, Herba Urariae crinitae 8 ~ 13 parts, Radix seu Folium callicarpae arboreae 25 ~ 30 parts, Radix Boehmeriae 20 ~ 25 parts, Herba Clinopodii Polycephali 30 ~ 35 parts, 17 ~ 22 parts, Herba Evolvuli Alsinoides, Herba Lamii Amplexicaulis 23 ~ 28 parts, Herba stellariae mediae 12 ~ 17 parts, Caulis Marsdeniae tinctoriae 24 ~ 29 parts, Eucheuma gelatinosum 17 ~ 22 parts, Caulis et Folium Brassicae campestris 25 ~ 30 parts and Medulla Stachyuri (Medulla Helwingiae) 13 ~ 18 parts.

4. the Chinese medicine as described in claims 1 to 3, is characterized in that, the ratio of weight and number of each raw medicinal material of described Chinese medicine is as follows: Herba Centellae 18 parts, Calendula officinalis spends 12 parts, Radix Smilacis nanae 26 parts, Herba Eupatorii Heterophylli 14 parts, Herba Urariae crinitae 12 parts, Radix seu Folium callicarpae arboreae 27 parts, Radix Boehmeriae 24 parts, Herba Clinopodii Polycephali 32 parts, 20 parts, Herba Evolvuli Alsinoides, Herba Lamii Amplexicaulis 24 parts, Herba stellariae mediae 16 parts, Caulis Marsdeniae tinctoriae 25 parts, Eucheuma gelatinosum 21 parts, Caulis et Folium Brassicae campestris 26 parts and Medulla Stachyuri (Medulla Helwingiae) 17 parts.

5. the Chinese medicine as described in Claims 1-4, is characterized in that, the ratio of weight and number of each raw medicinal material of described Chinese medicine is as follows: Herba Centellae 16 parts, Calendula officinalis spends 14 parts, Radix Smilacis nanae 23 parts, Herba Eupatorii Heterophylli 16 parts, Herba Urariae crinitae 10 parts, Radix seu Folium callicarpae arboreae 28 parts, Radix Boehmeriae 22 parts, Herba Clinopodii Polycephali 33 parts, 18 parts, Herba Evolvuli Alsinoides, Herba Lamii Amplexicaulis 26 parts, Herba stellariae mediae 14 parts, Caulis Marsdeniae tinctoriae 28 parts, Eucheuma gelatinosum 18 parts, Caulis et Folium Brassicae campestris 28 parts and Medulla Stachyuri (Medulla Helwingiae) 15 parts.

6. the Chinese medicine as described in claim 1 to 5, is characterized in that, the dosage form of described Chinese medicine is capsule, and its preparation method comprises the following steps:

The first step, is mixed in proportion each for described Chinese medicine raw medicinal material, and adding relative to the determining alcohol of mixture quality 2 ~ 4 times is the ethanol of 85 ~ 95%, reflux 1 ~ 3 hour, extracts, and filters acquisition first extracting solution; It is the ethanol of 85 ~ 95% that the medicinal residues that filtration obtains add relative to the determining alcohol of described medicinal residues quality 1 ~ 2 times again, reflux 1 ~ 3 hour, extracts, and filters acquisition second extracting solution; First extracting solution and the second extracting solution are merged, concentrating under reduced pressure removing alcohol solvent, dry, obtain and get dry extract;

Second step, is placed on the dry cream that the first step obtains in super micron mill and pulverizes 1 ~ 2 hour, pulverize, sieve, obtain 300 order ~ 400 object micropowders;

3rd step, adds Pulvis Talci, magnesium stearate successively in the micropowders that second step obtains, and carries out mixing process, obtains capsule 's content; Described micropowders, magnesium stearate and talcous weight ratio are 100: 0.15 ~ 0.5:0.15 ~ 0.5, incapsulate in housing by described capsule 's content, obtain capsule finished product.

7. the Chinese medicine as described in claim 1 to 5, is characterized in that, the dosage form of described Chinese medicine is powder, and its preparation method comprises the following steps:

The first step, is mixed in proportion described raw medicinal material, is ground into powder;

Second step, the first step is obtained powder and add in cold water and soak 6 hours ~ 12 hours, with slow fire boiling, decocting time is 3 hours ~ 5 hours, decoction liquor is filtered, obtains the first filtrate, and the quality of the water added is 2 ~ 4 times of the powder quality that the first step obtains;

3rd step, filters second step the filtering residue obtained and again adds in cold water, with slow fire boiling 2 hours ~ 4 hours, filters acquisition second filtrate, and the quality of the water added is 2 ~ 4 times of the powder quality that second step obtains;

4th step, the second filtrate mixing that the first filtrate obtain second step and the 3rd step obtain, concentrating under reduced pressure, except anhydrating, dry, pulverize powdered, and granularity is 80 ~ 120 orders;

5th step, in the powder that described 4th step obtains, add starch, the percentage by weight of described starch in described powder is 15% ~ 30%, and by the material pouch after mixing or packing box subpackage, every 5 ~ 10 grams is one bag or a box subpackage.

8. a preparation method for Chinese medicine described in claim 1 to 5, is characterized in that, the dosage form of described Chinese medicine is capsule, and its preparation method comprises the following steps:

The first step, is mixed in proportion each for described Chinese medicine raw medicinal material, and adding relative to the determining alcohol of mixture quality 2 ~ 4 times is the ethanol of 85 ~ 95%, reflux 1 ~ 3 hour, extracts, and filters acquisition first extracting solution; It is the ethanol of 85 ~ 95% that the medicinal residues that filtration obtains add relative to the determining alcohol of described medicinal residues quality 1 ~ 2 times again, reflux 1 ~ 3 hour, extracts, and filters acquisition second extracting solution; First extracting solution and the second extracting solution are merged, concentrating under reduced pressure removing alcohol solvent, dry, obtain and get dry extract;

Second step, is placed on the dry cream that the first step obtains in super micron mill and pulverizes 1 ~ 2 hour, pulverize, sieve, obtain 300 order ~ 400 object micropowders;

3rd step, adds Pulvis Talci, magnesium stearate successively in the micropowders that second step obtains, and carries out mixing process, obtains capsule 's content; Described micropowders, magnesium stearate and talcous weight ratio are 100: 0.15 ~ 0.5:0.15 ~ 0.5, incapsulate in housing by described capsule 's content, obtain capsule finished product.

9. a preparation method for Chinese medicine described in claim 1 to 5, is characterized in that, the dosage form of described Chinese medicine is powder, and its preparation method comprises the following steps:

The first step, is mixed in proportion described raw medicinal material, is ground into powder;

Second step, the first step is obtained powder and add in cold water and soak 6 hours ~ 12 hours, with slow fire boiling, decocting time is 3 hours ~ 5 hours, decoction liquor is filtered, obtains the first filtrate, and the quality of the water added is 2 ~ 4 times of the powder quality that the first step obtains;

3rd step, filters second step the filtering residue obtained and again adds in cold water, with slow fire boiling 2 hours ~ 4 hours, filters acquisition second filtrate, and the quality of the water added is 2 ~ 4 times of the powder quality that second step obtains;

4th step, the second filtrate mixing that the first filtrate obtain second step and the 3rd step obtain, concentrating under reduced pressure, except anhydrating, dry, pulverize powdered, and granularity is 80 ~ 120 orders;

5th step, in the powder that described 4th step obtains, add starch, the percentage by weight of described starch in described powder is 15% ~ 30%, and by the material pouch after mixing or packing box subpackage, every 5 ~ 10 grams is one bag or a box subpackage.