CN105164151B - TNFα抑制剂多肽、编码多肽的多核苷酸、表达多肽的细胞和生成多肽的方法 - Google Patents
TNFα抑制剂多肽、编码多肽的多核苷酸、表达多肽的细胞和生成多肽的方法 Download PDFInfo
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- CN105164151B CN105164151B CN201480022865.6A CN201480022865A CN105164151B CN 105164151 B CN105164151 B CN 105164151B CN 201480022865 A CN201480022865 A CN 201480022865A CN 105164151 B CN105164151 B CN 105164151B
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361773401P | 2013-03-06 | 2013-03-06 | |
| US201361773431P | 2013-03-06 | 2013-03-06 | |
| US61/773,431 | 2013-03-06 | ||
| US61/773,401 | 2013-03-06 | ||
| PCT/IL2014/050228 WO2014136114A1 (en) | 2013-03-06 | 2014-03-06 | TNF alpha INHIBITOR POLYPEPTIDES, POLYNUCLEOTIDES ENCODING SAME, CELLS EXPRESSING SAME AND METHODS OF PRODUCING SAME |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105164151A CN105164151A (zh) | 2015-12-16 |
| CN105164151B true CN105164151B (zh) | 2020-01-07 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201480022865.6A Expired - Fee Related CN105164151B (zh) | 2013-03-06 | 2014-03-06 | TNFα抑制剂多肽、编码多肽的多核苷酸、表达多肽的细胞和生成多肽的方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US20160017020A1 (enExample) |
| EP (1) | EP2964668B1 (enExample) |
| JP (1) | JP6454650B2 (enExample) |
| CN (1) | CN105164151B (enExample) |
| AU (1) | AU2014224171B2 (enExample) |
| BR (1) | BR112015021708A2 (enExample) |
| CA (2) | CA2904035A1 (enExample) |
| WO (2) | WO2014136114A1 (enExample) |
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| ES2616728T3 (es) | 2008-05-23 | 2017-06-14 | Siwa Corporation | Procedimientos y composiciones para facilitar la regeneración |
| US8721571B2 (en) | 2010-11-22 | 2014-05-13 | Siwa Corporation | Selective removal of cells having accumulated agents |
| EP2964669B1 (en) | 2013-03-06 | 2018-09-12 | Protalix Ltd. | Use of plant cells expressing a tnfalpha polypeptide inhibitor in therapy |
| BR112015021708A2 (pt) | 2013-03-06 | 2017-08-29 | Protalix Ltd | Inibidor de polipetídeo do tnfa, polinucleotídeo isolado, estrutura de expressão de ácido nucleico, célula de planta, composição farmacêutica e método de produção de um inibidor de polipeptídeo do tnfa |
| US10000551B2 (en) | 2014-09-11 | 2018-06-19 | Protalix Ltd. | Chimeric polypeptides, polynucleotides encoding same, cells expressing same and methods of producing same |
| IL251210B2 (en) * | 2014-09-19 | 2023-12-01 | Siwa Corp | Anti-aging antibodies for the treatment of inflammation and autoimmune disorders |
| US9993535B2 (en) | 2014-12-18 | 2018-06-12 | Siwa Corporation | Method and composition for treating sarcopenia |
| US10358502B2 (en) | 2014-12-18 | 2019-07-23 | Siwa Corporation | Product and method for treating sarcopenia |
| CN109071675A (zh) | 2016-02-19 | 2018-12-21 | Siwa有限公司 | 使用高级糖化终产物(age)的抗体治疗癌症、杀死转移性癌细胞和预防癌症转移的方法和组合物 |
| CA3057829A1 (en) | 2016-04-15 | 2017-10-19 | Siwa Corporation | Anti-age antibodies for treating neurodegenerative disorders |
| EP3475306A1 (en) | 2016-06-23 | 2019-05-01 | Siwa Corporation | Vaccines for use in treating various diseases and disorders |
| US10925937B1 (en) | 2017-01-06 | 2021-02-23 | Siwa Corporation | Vaccines for use in treating juvenile disorders associated with inflammation |
| US10858449B1 (en) | 2017-01-06 | 2020-12-08 | Siwa Corporation | Methods and compositions for treating osteoarthritis |
| US10961321B1 (en) | 2017-01-06 | 2021-03-30 | Siwa Corporation | Methods and compositions for treating pain associated with inflammation |
| US10995151B1 (en) | 2017-01-06 | 2021-05-04 | Siwa Corporation | Methods and compositions for treating disease-related cachexia |
| US10919957B2 (en) | 2017-04-13 | 2021-02-16 | Siwa Corporation | Humanized monoclonal advanced glycation end-product antibody |
| US11518801B1 (en) | 2017-12-22 | 2022-12-06 | Siwa Corporation | Methods and compositions for treating diabetes and diabetic complications |
| EP4661892A1 (en) * | 2023-02-08 | 2025-12-17 | Navigen, Inc. | Tnf-alpha binding agents and methods of using the same |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002012502A2 (en) * | 2000-08-07 | 2002-02-14 | Centocor, Inc. | Anti-tnf antibodies, compositions, methods and uses |
| CN1533438A (zh) * | 2001-06-08 | 2004-09-29 | �����Ŵ��Ƽ���˾ | 在植物生产蛋白质的方法 |
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- 2014-03-06 CA CA2902298A patent/CA2902298A1/en not_active Abandoned
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- 2014-03-06 WO PCT/IL2014/050228 patent/WO2014136114A1/en not_active Ceased
- 2014-03-06 EP EP14716434.7A patent/EP2964668B1/en active Active
- 2014-03-06 CN CN201480022865.6A patent/CN105164151B/zh not_active Expired - Fee Related
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Also Published As
| Publication number | Publication date |
|---|---|
| CA2904035A1 (en) | 2014-09-12 |
| CN105164151A (zh) | 2015-12-16 |
| AU2014224171A1 (en) | 2015-10-22 |
| US20180327476A1 (en) | 2018-11-15 |
| US20160017021A1 (en) | 2016-01-21 |
| JP2016510736A (ja) | 2016-04-11 |
| AU2014224171B2 (en) | 2018-02-01 |
| EP2964668A1 (en) | 2016-01-13 |
| WO2014136113A1 (en) | 2014-09-12 |
| WO2014136114A1 (en) | 2014-09-12 |
| US20160017020A1 (en) | 2016-01-21 |
| JP6454650B2 (ja) | 2019-01-23 |
| US10730925B2 (en) | 2020-08-04 |
| EP2964668B1 (en) | 2019-11-27 |
| CA2902298A1 (en) | 2014-09-12 |
| BR112015021708A2 (pt) | 2017-08-29 |
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