CN105130924A - 一种制备4-甲基噻唑-5-甲酸乙酯的方法 - Google Patents
一种制备4-甲基噻唑-5-甲酸乙酯的方法 Download PDFInfo
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- CN105130924A CN105130924A CN201510438249.5A CN201510438249A CN105130924A CN 105130924 A CN105130924 A CN 105130924A CN 201510438249 A CN201510438249 A CN 201510438249A CN 105130924 A CN105130924 A CN 105130924A
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- reaction
- methylthiazole
- carboxylate
- product
- preparation
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Abstract
Description
Claims (3)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN201510438249.5A CN105130924B (zh) | 2015-07-22 | 2015-07-22 | 一种制备4‑甲基噻唑‑5‑甲酸乙酯的方法 |
Applications Claiming Priority (1)
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CN201510438249.5A CN105130924B (zh) | 2015-07-22 | 2015-07-22 | 一种制备4‑甲基噻唑‑5‑甲酸乙酯的方法 |
Publications (2)
Publication Number | Publication Date |
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CN105130924A true CN105130924A (zh) | 2015-12-09 |
CN105130924B CN105130924B (zh) | 2017-03-15 |
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CN201510438249.5A Active CN105130924B (zh) | 2015-07-22 | 2015-07-22 | 一种制备4‑甲基噻唑‑5‑甲酸乙酯的方法 |
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CN (1) | CN105130924B (zh) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106977471A (zh) * | 2017-04-21 | 2017-07-25 | 常州佳德医药科技有限公司 | 一种制备4‑甲基噻唑‑5‑甲酸乙酯的方法 |
CN115925649A (zh) * | 2022-10-09 | 2023-04-07 | 深圳市茵诺圣生物科技有限公司 | 一种连续流制备4-甲基噻唑-5-甲醛的方法 |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002051849A1 (fr) * | 2000-12-26 | 2002-07-04 | Daiichi Pharmaceutical Co., Ltd. | Inhibiteurs cdk4 |
CN101475541A (zh) * | 2009-02-09 | 2009-07-08 | 扬州哈泰克材料有限公司 | 4-甲基噻唑-5-羧酸的一种制备方法 |
CN103232404A (zh) * | 2013-04-27 | 2013-08-07 | 黑龙江大学 | 4-甲基噻唑的制备方法 |
CN103772315A (zh) * | 2014-01-07 | 2014-05-07 | 山东汇海医药化工有限公司 | 一种一步合成4-甲基噻唑-5-甲酸乙酯的方法 |
-
2015
- 2015-07-22 CN CN201510438249.5A patent/CN105130924B/zh active Active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002051849A1 (fr) * | 2000-12-26 | 2002-07-04 | Daiichi Pharmaceutical Co., Ltd. | Inhibiteurs cdk4 |
CN101475541A (zh) * | 2009-02-09 | 2009-07-08 | 扬州哈泰克材料有限公司 | 4-甲基噻唑-5-羧酸的一种制备方法 |
CN103232404A (zh) * | 2013-04-27 | 2013-08-07 | 黑龙江大学 | 4-甲基噻唑的制备方法 |
CN103772315A (zh) * | 2014-01-07 | 2014-05-07 | 山东汇海医药化工有限公司 | 一种一步合成4-甲基噻唑-5-甲酸乙酯的方法 |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106977471A (zh) * | 2017-04-21 | 2017-07-25 | 常州佳德医药科技有限公司 | 一种制备4‑甲基噻唑‑5‑甲酸乙酯的方法 |
CN115925649A (zh) * | 2022-10-09 | 2023-04-07 | 深圳市茵诺圣生物科技有限公司 | 一种连续流制备4-甲基噻唑-5-甲醛的方法 |
Also Published As
Publication number | Publication date |
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CN105130924B (zh) | 2017-03-15 |
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Denomination of invention: A method for preparing 4-methylthiazole-5-carboxylic acid ethyl ester Effective date of registration: 20230328 Granted publication date: 20170315 Pledgee: Bengbu financing guarantee Group Co.,Ltd. Pledgor: CHINA SYNCHEM TECHNOLOGY Co.,Ltd. Registration number: Y2023980036635 |
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Date of cancellation: 20230524 Granted publication date: 20170315 Pledgee: Bengbu financing guarantee Group Co.,Ltd. Pledgor: CHINA SYNCHEM TECHNOLOGY Co.,Ltd. Registration number: Y2023980036635 |
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Denomination of invention: A method for preparing 4-methylthiazole-5-neneneba ethyl formate Effective date of registration: 20230531 Granted publication date: 20170315 Pledgee: Bengbu financing guarantee Group Co.,Ltd. Pledgor: CHINA SYNCHEM TECHNOLOGY Co.,Ltd. Registration number: Y2023980042433 |
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