CN105123706A - Bactericide with epoxiconazole and cinnamyl aldehyde - Google Patents
Bactericide with epoxiconazole and cinnamyl aldehyde Download PDFInfo
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- CN105123706A CN105123706A CN201510697901.5A CN201510697901A CN105123706A CN 105123706 A CN105123706 A CN 105123706A CN 201510697901 A CN201510697901 A CN 201510697901A CN 105123706 A CN105123706 A CN 105123706A
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- bactericide
- epoxiconazole
- cinnamic acid
- cinnamyl aldehyde
- cinnamyl
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Abstract
The invention relates to a bactericide with epoxiconazole and cinnamyl aldehyde. The effective ingredients include epoxiconazole and cinnamyl aldehyde. The weight ratio of epoxiconazole to cinnamyl aldehyde is 1-5 to 1. The application of the bactericide to prevention and control of rice sheath blight disease is further required to be protected. Traditional Chinese medicine, namely, cinnamyl aldehyde, is mixed with ingredients of the bactericide; tests prove that after cinnamyl aldehyde is added to the ingredients of the bactericide, the drug resistance of pathogen to the bactericide can be reversed, and therefore the control effect of the bactericide is improved, drug cost and drug residuals can be greatly reduced, more economic benefits are created for farmers, and meanwhile food safety is ensured.
Description
Technical field
The present invention relates to technical field of pesticide, specifically a kind of bactericide containing epoxiconazole and cinnamic acid.
Background technology
Cinnamic acid is cinnamon spirit main body of oil, and another name is called beautiful osmanthus, is the kind that Lauraceae Chinese cassia tree belongs to.Cinnamic acid is also called cinnaldehydrum, has very strong aromatic odor, and pure cinnamic acid is colourless or faint yellow vigorous thick liquid, and easily oxidized in atmosphere, naturally occurring cinnamic acid mostly is transconfiguration, is present in the plant corpuss such as Chinese cassia tree in a large number.
At present, the research of cinnamyl alcohol is limited to the application of food industry applications and medical industry more, such as, research finds, the mould, aspergillus, Mucor, head mold, the bud branch that obtain are mould, sickle-like bacteria carries out antibacterial activity test to being separated in food to utilize cinnamic acid, minimal inhibitory concentration can reach 6mg/kg, and anti-mold effect is good; Utilize cinnamic acid missible oil to test the fresh-keeping of mango, result shows more remarkable than the control efficiency of conventional sterilants; Suppress the mechanism of aspergillus flavus to be studied to cinnamic acid, think that first cinnamic acid damages its cell membrane, and then change intracellular space structure, as protein, nucleic acid etc.Also own through showing that cinnamic acid all has significant bactericidal action to Escherichia coli, staphylococcus aureus, salmonella, hay bacillus, proteus etc. in medical industry.But, do not retrieve the relevant report being applied to the water prevention rice sheath blight at present.
Epoxiconazole (Epoxiconazole), chemical name: (2RS, 3SR)-3-(2-chlorphenyl)-2-(4-fluorophenyl)-2-[(1H1,2,4-triazol-1-yl) methyl] oxirane, chemical structural formula is:
Epoxiconazole is a kind of interior absorption triazole bactericidal agent, its active component epoxiconazole suppresses the synthesis of germ ergosterol, hinder the formation of germ cell wall, and epoxiconazole molecule has powerful compatibility to a kind of fungal enzyme (14-dencthylase), compared with bactericide known at present, can more effectively suppress germ fungal pathogens.Epoxiconazole can improve all fourth matter enzymic activitys of crop, causes the contraction of fungi haustorium, and suppress germ to invade, this is epoxiconazole unique characteristic in all triazole type products.Epoxiconazole has good preventive effect to the disease such as anthracnose, white rot on leaf spot, powdery mildew, rust and the grape on the crops such as banana, green onion garlic, celery, Kidney bean, melon, asparagus, peanut, beet.In recent years due to its large-area popularization, pathogen is caused to reduce its susceptibility, resistance grow.
Summary of the invention
The technical problem to be solved in the present invention is, for the deficiency that above-mentioned existing bactericide exists, a kind of bactericide containing epoxiconazole and cinnamic acid is provided, overcome that existing bactericide causes due to resistance problems preventive effect reduces, consumption strengthens, residual high and defect that cost is high.
The present invention realizes the technical scheme that above-mentioned purpose takes: a kind of bactericide containing epoxiconazole and cinnamic acid, active ingredient is made up of epoxiconazole and cinnamic acid, and described cinnamic acid and the weight ratio of epoxiconazole are 1-5:1.
The present invention's also application of claimed described bactericide on the water prevention rice sheath blight.
The present invention utilizes Chinese traditional medicine cinnamon aldehyde and microbiocidal composition mixture, test proves, add cinnamic acid in germicide constituent after, the pesticide resistance of pathogen to bactericide can be reversed, thus improve the control efficiency of bactericide, and can significantly reduce drug cost and medicament residue, for peasant household creates higher economic benefit, also ensure that food security simultaneously.
Embodiment
Below in conjunction with test data and embodiment, technical scheme of the present invention and beneficial effect are described further.
One indoor joint toxicity measuring test
For clear and definite bactericide (propiconazole, SYP-3375, carbendazim, epoxiconazole, prochloraz, Fluoxastrobin, thifluzamide, tetraconazole, Tebuconazole, azoles alcohol, jinggangmeisu, Difenoconazole) and cinnamic acid mixture affect the virulence of Rhizoctonia solani Kuhn, mycelial growth rate method is adopted to carry out indoor measurement.
Rhizoctonia solani Kuhn is separated from surrounding area, Guigang, purifying cultivate after through Koch's Postulates verify its pathogenic after by strain inoculation in PDA medium, at 25 DEG C, under 90% damp condition, cultivate 5d, break into bacterium cake with 0.4cm card punch after mycelia covers with culture dish and use.
Cinnamic acid and bactericide are pressed active ingredient part by weight 1:1 respectively, 2:1, 5:1, 10:1 mixing is made into binary built agent as mixture 1-mixture 4, bactericide single dose and mixture 1-mixture 4 are respectively diluted 6 concentration according to geometric ratio gradient from 10ppm, blank is made with clear water process, make PDA flat board, arranging without medicament is contrast, every concentration repeats 3 times, after aseptically the bacterium cake accomplished fluently being inverted in the dull and stereotyped central authorities of each process PDA, flat board is placed in 25 DEG C, cultivate under 90% damp condition, investigation result when mycelial growth diameter reaches culture dish diameter about 50%, calculate inhibiting rate, and the EC of each chemicals treatment is calculated by DPS Software of Data Statistics
50and composite co-toxicity coefficient.Because cinnamic acid single dose does not almost affect for Rhizoctonia solani Kuhn, therefore the present invention calculate composite co-toxicity coefficient time by the EC of cinnamic acid single dose
50be designated as 0, the EC of co-toxicity coefficient=composite
50the EC of/bactericide single dose
50.Statistics is as shown in the table.
As can be known from the above table: cinnamic acid and propiconazole, SYP-3375, carbendazim, epoxiconazole, prochloraz, Fluoxastrobin, thifluzamide, tetraconazole, Tebuconazole, azoles alcohol, jinggangmeisu all has obvious synergistic effect to Rhizoctonia solani Kuhn afterwards in 1-5:1 ratio is composite, and cinnamic acid and propiconazole, SYP-3375, carbendazim, epoxiconazole, prochloraz, Fluoxastrobin, thifluzamide, tetraconazole, Tebuconazole, azoles alcohol, jinggangmeisu shows inhibitory action to Rhizoctonia solani Kuhn afterwards in 10:1 ratio is composite, and cinnamic acid and Difenoconazole are added or inhibitory action in composite rear to show Rhizoctonia solani Kuhn of 1-10:1 ratio.
Two field medicine effect tests
Test medicine
12 single doses: propiconazole, SYP-3375, carbendazim, epoxiconazole, prochloraz, Fluoxastrobin, thifluzamide, tetraconazole, Tebuconazole, azoles alcohol, jinggangmeisu, Difenoconazole;
12 mixed agents: be the weight ratio of 2:1 according to cinnamic acid and bactericide, add cinnamic acid in above-mentioned single dose.
Test establishes 25 process altogether together with blank, and each process repeats for 3 times, 75 communities, each community randomized arrangement.
Test method
By above-mentioned single dose and mixed agent even spraying, the effective ingredient consumption conveniently consumption use of bactericide single dose, the microbiocidal composition consumption in mixture and single dose are together.21 days investigation rice sheath blight disease controlling results after medicine.
Result of the test
Bactericide | Single dose preventive effect (%) | Cinnamic acid and bactericide are 2:1 mixture (%) |
Propiconazole | 75.03 | 88.62 |
SYP-3375 | 69.74 | 85.33 |
Carbendazim | 60.99 | 94.53 |
Epoxiconazole | 75.73 | 90.41 |
Prochloraz | 70.84 | 89.63 |
Fluoxastrobin | 76.33 | 87.30 |
Thifluzamide | 62.02 | 81.72 |
Tetraconazole | 69.17 | 87.13 |
Tebuconazole | 73.17 | 84.29 |
Azoles alcohol | 83.22 | 94.28 |
Jinggangmeisu | 60.79 | 91.94 |
Difenoconazole | 76.02 | 77.11 |
As can be known from the above table: cinnamic acid and propiconazole, SYP-3375, carbendazim, epoxiconazole, prochloraz, Fluoxastrobin, thifluzamide, tetraconazole, Tebuconazole, azoles alcohol well, ridge mycin are more obvious than single dose good in the composite rear preventive effect to rice sheath blight disease of 2:1 ratio, and cinnamic acid and Difenoconazole are more or less the same in the composite rear preventive effect to rice sheath blight disease of 2:1 ratio and single dose.
Claims (2)
1. contain a bactericide for epoxiconazole and cinnamic acid, it is characterized in that, active ingredient is made up of epoxiconazole and cinnamic acid, and described cinnamic acid and the weight ratio of epoxiconazole are 1-5:1.
2. the application of bactericide according to claim 1 on the water prevention rice sheath blight.
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CN201510697901.5A CN105123706A (en) | 2015-10-26 | 2015-10-26 | Bactericide with epoxiconazole and cinnamyl aldehyde |
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Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0094564A2 (en) * | 1982-05-14 | 1983-11-23 | BASF Aktiengesellschaft | Azolyl-methyl oxiranes, their preparation and use as medicaments and plant protecting agents |
CN102388872A (en) * | 2011-11-30 | 2012-03-28 | 江苏省农业科学院 | Bactericide for promoting growth and controlling rice sheath blight and application thereof |
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2015
- 2015-10-26 CN CN201510697901.5A patent/CN105123706A/en active Pending
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0094564A2 (en) * | 1982-05-14 | 1983-11-23 | BASF Aktiengesellschaft | Azolyl-methyl oxiranes, their preparation and use as medicaments and plant protecting agents |
CN102388872A (en) * | 2011-11-30 | 2012-03-28 | 江苏省农业科学院 | Bactericide for promoting growth and controlling rice sheath blight and application thereof |
Non-Patent Citations (2)
Title |
---|
徐伟松: "氟环唑对广东水稻纹枯病的田间防治试验", 《农药科学与管理》 * |
黄秋良: "12.5%氟环唑防治水稻纹枯病药效研究", 《现代农业科技》 * |
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Application publication date: 20151209 |