CN105122051B - 分析系统 - Google Patents

分析系统 Download PDF

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Publication number
CN105122051B
CN105122051B CN201480020182.7A CN201480020182A CN105122051B CN 105122051 B CN105122051 B CN 105122051B CN 201480020182 A CN201480020182 A CN 201480020182A CN 105122051 B CN105122051 B CN 105122051B
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China
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mentioned
ion
analysis
mass
information
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Chinese (zh)
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CN105122051A (zh
Inventor
佐竹宏之
桥本雄郎
桥本雄一郎
管正男
长谷川英树
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Hitachi Ltd
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Hitachi Ltd
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    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/0027—Methods for using particle spectrometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G01N30/7233—Mass spectrometers interfaced to liquid or supercritical fluid chromatograph
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/62—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
    • G01N27/622—Ion mobility spectrometry
    • G01N27/624—Differential mobility spectrometry [DMS]; Field asymmetric-waveform ion mobility spectrometry [FAIMS]
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn

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  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
CN201480020182.7A 2013-04-15 2014-04-10 分析系统 Active CN105122051B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2013-084950 2013-04-15
JP2013084950A JP5997650B2 (ja) 2013-04-15 2013-04-15 分析システム
PCT/JP2014/060397 WO2014171390A1 (ja) 2013-04-15 2014-04-10 分析システム

Publications (2)

Publication Number Publication Date
CN105122051A CN105122051A (zh) 2015-12-02
CN105122051B true CN105122051B (zh) 2017-07-04

Family

ID=51731333

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201480020182.7A Active CN105122051B (zh) 2013-04-15 2014-04-10 分析系统

Country Status (6)

Country Link
US (1) US10036737B2 (enExample)
JP (1) JP5997650B2 (enExample)
CN (1) CN105122051B (enExample)
DE (1) DE112014001182B4 (enExample)
GB (1) GB2527441B (enExample)
WO (1) WO2014171390A1 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6278658B2 (ja) * 2013-10-24 2018-02-14 アトナープ株式会社 分析方法
US9500624B2 (en) * 2014-06-13 2016-11-22 Thermo Finnigan Llc System comprising a mass spectrometer coupled to a FAIMS apparatus and methods of operation
US10041907B2 (en) * 2014-09-26 2018-08-07 Micromass Uk Limited Accurate mobility chromatograms
WO2016125061A1 (en) * 2015-02-05 2016-08-11 Dh Technologies Development Pte. Ltd. Rapid scanning of wide quadrupole rf windows while toggling fragmentation energy
EP3254301B1 (en) * 2015-02-06 2021-03-31 DH Technologies Development Pte. Ltd. Lipid screening platform allowing a complete solution for lipidomics research
JP6575384B2 (ja) * 2016-02-05 2019-09-18 株式会社島津製作所 液体クロマトグラフ装置
EP3425387B1 (en) * 2016-03-01 2023-08-23 Shimadzu Corporation Chromatograph device
CN105738463A (zh) * 2016-05-11 2016-07-06 北京化工大学 一种快速分析离子迁移谱出峰物质组成的方法
EP3508843B1 (en) * 2016-09-01 2022-11-02 Shimadzu Corporation Mass spectrometry data processing device
JP7105049B2 (ja) * 2017-10-02 2022-07-22 日本電子株式会社 質量分析データ処理装置、及び質量分析データ処理方法
US11162922B2 (en) 2018-08-03 2021-11-02 Shimadzu Corporation Liquid chromatograph device
WO2021122784A1 (en) * 2019-12-17 2021-06-24 Roche Diagnostics Gmbh Method and device for multiple transition monitoring
JP7335449B2 (ja) * 2020-01-10 2023-08-29 エフ． ホフマン－ラ ロシュ アーゲー 質量分析システムの較正
US20250258132A1 (en) * 2022-04-14 2025-08-14 Dh Technologies Development Pte. Ltd. Systems and Methods for Sync of Instrument Voltages with Orthogonal Ion Pulsing
US11978619B2 (en) 2022-07-20 2024-05-07 Infineon Technologies Austria Ag Ion shuttling system with compensation electrodes for ion trap
CN116359320B (zh) * 2023-03-20 2025-11-28 中国科学院合肥物质科学研究院 一种离子迁移谱快速扫描及谱图修正方法和装置
WO2025058677A2 (en) * 2023-04-27 2025-03-20 Board Of Regents, The University Of Texas System Compositions and methods for encrypting, storing, and decrypting information in oligomers
CN120221382A (zh) * 2023-12-26 2025-06-27 株式会社岛津制作所 串联离子迁移谱仪及离子迁移率分析方法

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1585666A (zh) * 2001-04-17 2005-02-23 查尔斯斯塔克布料实验室公司 用于电喷雾增强的高电场非对称离子淌度光谱测定仪的方法和装置
CN101151705A (zh) * 2005-03-29 2008-03-26 萨默费尼根有限公司 关于质谱仪的改进
CN101335177A (zh) * 2007-06-29 2008-12-31 株式会社日立制作所 离子阱、质量分析计、离子迁移率分析计
US20090266983A1 (en) * 2008-04-25 2009-10-29 Shimadzu Corporation Method for processing mass analysis data and mass spectrometer
CN101907614A (zh) * 2010-07-26 2010-12-08 中国科学院长春应用化学研究所 超高效液相色谱和质谱联用筛选组织蛋白酶b抑制剂的方法
CN102308361A (zh) * 2009-02-05 2012-01-04 株式会社岛津制作所 Ms/ms型质谱分析装置
CN202172060U (zh) * 2008-05-30 2012-03-21 珀金埃尔默健康科学股份有限公司 用于电离化学种的设备

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6498342B1 (en) * 1997-06-02 2002-12-24 Advanced Research & Technology Institute Ion separation instrument
US6815668B2 (en) * 1999-07-21 2004-11-09 The Charles Stark Draper Laboratory, Inc. Method and apparatus for chromatography-high field asymmetric waveform ion mobility spectrometry
JP2005513414A (ja) 2001-06-30 2005-05-12 シオネックス・コーポレーション 電界中におけるデータ収集および未知イオン種識別のためのシステム
US7473892B2 (en) 2003-08-13 2009-01-06 Hitachi High-Technologies Corporation Mass spectrometer system
JP4491299B2 (ja) * 2004-08-11 2010-06-30 株式会社日立ハイテクノロジーズ 質量分析装置
JP4654087B2 (ja) * 2005-03-18 2011-03-16 株式会社日立ハイテクノロジーズ 質量分析計及び質量分析方法
JP5542433B2 (ja) 2006-05-26 2014-07-09 ウオーターズ・テクノロジーズ・コーポレイシヨン イオン検出およびｎ次元データのパラメータ推定
US7550717B1 (en) * 2006-11-30 2009-06-23 Thermo Finnigan Llc Quadrupole FAIMS apparatus
JP5125248B2 (ja) * 2007-06-22 2013-01-23 株式会社日立製作所 イオンモビリティ分光計
US7884318B2 (en) 2008-01-16 2011-02-08 Metabolon, Inc. Systems, methods, and computer-readable medium for determining composition of chemical constituents in a complex mixture
EP2409315B1 (en) * 2009-03-17 2019-08-14 DH Technologies Development Pte. Ltd. Ion optics drain for ion mobility
GB201100301D0 (en) 2011-01-10 2011-02-23 Micromass Ltd Method of processing multidmensional mass spectrometry data

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1585666A (zh) * 2001-04-17 2005-02-23 查尔斯斯塔克布料实验室公司 用于电喷雾增强的高电场非对称离子淌度光谱测定仪的方法和装置
CN101151705A (zh) * 2005-03-29 2008-03-26 萨默费尼根有限公司 关于质谱仪的改进
CN101335177A (zh) * 2007-06-29 2008-12-31 株式会社日立制作所 离子阱、质量分析计、离子迁移率分析计
US20090266983A1 (en) * 2008-04-25 2009-10-29 Shimadzu Corporation Method for processing mass analysis data and mass spectrometer
CN202172060U (zh) * 2008-05-30 2012-03-21 珀金埃尔默健康科学股份有限公司 用于电离化学种的设备
CN102308361A (zh) * 2009-02-05 2012-01-04 株式会社岛津制作所 Ms/ms型质谱分析装置
CN101907614A (zh) * 2010-07-26 2010-12-08 中国科学院长春应用化学研究所 超高效液相色谱和质谱联用筛选组织蛋白酶b抑制剂的方法

Also Published As

Publication number Publication date
US10036737B2 (en) 2018-07-31
DE112014001182T5 (de) 2015-11-26
CN105122051A (zh) 2015-12-02
GB201515881D0 (en) 2015-10-21
JP5997650B2 (ja) 2016-09-28
WO2014171390A1 (ja) 2014-10-23
GB2527441A (en) 2015-12-23
US20160025692A1 (en) 2016-01-28
JP2014206497A (ja) 2014-10-30
DE112014001182B4 (de) 2022-03-17
GB2527441B (en) 2021-02-03

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