JP5997650B2 - 分析システム - Google Patents

分析システム Download PDF

Info

Publication number
JP5997650B2
JP5997650B2 JP2013084950A JP2013084950A JP5997650B2 JP 5997650 B2 JP5997650 B2 JP 5997650B2 JP 2013084950 A JP2013084950 A JP 2013084950A JP 2013084950 A JP2013084950 A JP 2013084950A JP 5997650 B2 JP5997650 B2 JP 5997650B2
Authority
JP
Japan
Prior art keywords
analysis
mass
ion
ions
measurement target
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2013084950A
Other languages
English (en)
Japanese (ja)
Other versions
JP2014206497A5 (enExample
JP2014206497A (ja
Inventor
宏之 佐竹
宏之 佐竹
橋本 雄一郎
雄一郎 橋本
管 正男
正男 管
長谷川 英樹
英樹 長谷川
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hitachi High Tech Corp
Original Assignee
Hitachi High Technologies Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to JP2013084950A priority Critical patent/JP5997650B2/ja
Application filed by Hitachi High Technologies Corp filed Critical Hitachi High Technologies Corp
Priority to CN201480020182.7A priority patent/CN105122051B/zh
Priority to DE112014001182.7T priority patent/DE112014001182B4/de
Priority to PCT/JP2014/060397 priority patent/WO2014171390A1/ja
Priority to GB1515881.9A priority patent/GB2527441B/en
Priority to US14/782,424 priority patent/US10036737B2/en
Publication of JP2014206497A publication Critical patent/JP2014206497A/ja
Publication of JP2014206497A5 publication Critical patent/JP2014206497A5/ja
Application granted granted Critical
Publication of JP5997650B2 publication Critical patent/JP5997650B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/62Detectors specially adapted therefor
    • G01N30/72Mass spectrometers
    • G01N30/7233Mass spectrometers interfaced to liquid or supercritical fluid chromatograph
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/62Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating the ionisation of gases, e.g. aerosols; by investigating electric discharges, e.g. emission of cathode
    • G01N27/622Ion mobility spectrometry
    • G01N27/624Differential mobility spectrometry [DMS]; Field asymmetric-waveform ion mobility spectrometry [FAIMS]
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/0027Methods for using particle spectrometers
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/004Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn

Landscapes

  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Electrochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
JP2013084950A 2013-04-15 2013-04-15 分析システム Active JP5997650B2 (ja)

Priority Applications (6)

Application Number Priority Date Filing Date Title
JP2013084950A JP5997650B2 (ja) 2013-04-15 2013-04-15 分析システム
DE112014001182.7T DE112014001182B4 (de) 2013-04-15 2014-04-10 Analysesystem
PCT/JP2014/060397 WO2014171390A1 (ja) 2013-04-15 2014-04-10 分析システム
GB1515881.9A GB2527441B (en) 2013-04-15 2014-04-10 Analysis system
CN201480020182.7A CN105122051B (zh) 2013-04-15 2014-04-10 分析系统
US14/782,424 US10036737B2 (en) 2013-04-15 2014-04-10 Analysis system

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2013084950A JP5997650B2 (ja) 2013-04-15 2013-04-15 分析システム

Publications (3)

Publication Number Publication Date
JP2014206497A JP2014206497A (ja) 2014-10-30
JP2014206497A5 JP2014206497A5 (enExample) 2016-03-31
JP5997650B2 true JP5997650B2 (ja) 2016-09-28

Family

ID=51731333

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013084950A Active JP5997650B2 (ja) 2013-04-15 2013-04-15 分析システム

Country Status (6)

Country Link
US (1) US10036737B2 (enExample)
JP (1) JP5997650B2 (enExample)
CN (1) CN105122051B (enExample)
DE (1) DE112014001182B4 (enExample)
GB (1) GB2527441B (enExample)
WO (1) WO2014171390A1 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6278658B2 (ja) * 2013-10-24 2018-02-14 アトナープ株式会社 分析方法
EP2955515B1 (en) * 2014-06-13 2017-12-27 Thermo Finnigan LLC Methods for operating a system comprising a mass spectrometer, ion mobility spectrometer and chromatograph
EP3198627B1 (en) * 2014-09-26 2025-10-29 Micromass UK Limited Accurate mobility chromatograms
JP6698668B2 (ja) * 2015-02-05 2020-05-27 ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド 断片化エネルギーを切り替えながらの幅広い四重極rf窓の高速スキャニング
WO2016125120A1 (en) * 2015-02-06 2016-08-11 Dh Technologies Development Pte. Ltd. Lipid screening platform allowing a complete solution for lipidomics research
JP6575384B2 (ja) * 2016-02-05 2019-09-18 株式会社島津製作所 液体クロマトグラフ装置
US10746709B2 (en) * 2016-03-01 2020-08-18 Shimadzu Corporation Chromatograph device
CN105738463A (zh) * 2016-05-11 2016-07-06 北京化工大学 一种快速分析离子迁移谱出峰物质组成的方法
US11232935B2 (en) * 2016-09-01 2022-01-25 Shimadzu Corporation Mass spectrometry data processing device
JP7105049B2 (ja) * 2017-10-02 2022-07-22 日本電子株式会社 質量分析データ処理装置、及び質量分析データ処理方法
US11162922B2 (en) 2018-08-03 2021-11-02 Shimadzu Corporation Liquid chromatograph device
WO2021122784A1 (en) * 2019-12-17 2021-06-24 Roche Diagnostics Gmbh Method and device for multiple transition monitoring
CN114930497B (zh) * 2020-01-10 2025-07-15 豪夫迈·罗氏有限公司 质谱系统的校准
WO2023199275A1 (en) * 2022-04-14 2023-10-19 Dh Technologies Development Pte. Ltd. Systems and methods for sync of instrument voltages with orthogonal ion pulsing
US11978619B2 (en) 2022-07-20 2024-05-07 Infineon Technologies Austria Ag Ion shuttling system with compensation electrodes for ion trap
CN116359320B (zh) * 2023-03-20 2025-11-28 中国科学院合肥物质科学研究院 一种离子迁移谱快速扫描及谱图修正方法和装置
WO2025058677A2 (en) * 2023-04-27 2025-03-20 Board Of Regents, The University Of Texas System Compositions and methods for encrypting, storing, and decrypting information in oligomers
CN120221382A (zh) * 2023-12-26 2025-06-27 株式会社岛津制作所 串联离子迁移谱仪及离子迁移率分析方法

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6498342B1 (en) * 1997-06-02 2002-12-24 Advanced Research & Technology Institute Ion separation instrument
US6815668B2 (en) * 1999-07-21 2004-11-09 The Charles Stark Draper Laboratory, Inc. Method and apparatus for chromatography-high field asymmetric waveform ion mobility spectrometry
WO2002083276A1 (en) * 2001-04-17 2002-10-24 The Charles Stark Draper Laboratory, Inc. Methods and apparatus for electrospray-augmented high field asymmetric ion mobility spectrometry
IL159590A0 (en) 2001-06-30 2004-06-01 Sionex Corp System for collection of data and identification of unknown ion species in an electric field
US7473892B2 (en) * 2003-08-13 2009-01-06 Hitachi High-Technologies Corporation Mass spectrometer system
JP4491299B2 (ja) * 2004-08-11 2010-06-30 株式会社日立ハイテクノロジーズ 質量分析装置
JP4654087B2 (ja) * 2005-03-18 2011-03-16 株式会社日立ハイテクノロジーズ 質量分析計及び質量分析方法
GB0506288D0 (en) * 2005-03-29 2005-05-04 Thermo Finnigan Llc Improvements relating to mass spectrometry
WO2007140327A2 (en) 2006-05-26 2007-12-06 Waters Investments Limited Ion detection and parameter estimation for n-dimensional data
US7550717B1 (en) * 2006-11-30 2009-06-23 Thermo Finnigan Llc Quadrupole FAIMS apparatus
JP5125248B2 (ja) * 2007-06-22 2013-01-23 株式会社日立製作所 イオンモビリティ分光計
JP4905270B2 (ja) * 2007-06-29 2012-03-28 株式会社日立製作所 イオントラップ、質量分析計、イオンモビリティ分析計
US7884318B2 (en) 2008-01-16 2011-02-08 Metabolon, Inc. Systems, methods, and computer-readable medium for determining composition of chemical constituents in a complex mixture
JP5251232B2 (ja) * 2008-04-25 2013-07-31 株式会社島津製作所 質量分析データ処理方法及び質量分析装置
CA2725612C (en) * 2008-05-30 2017-07-11 Perkinelmer Health Sciences, Inc. Single and multiple operating mode ion sources with atmospheric pressure chemical ionization
WO2010089798A1 (ja) * 2009-02-05 2010-08-12 株式会社島津製作所 Ms/ms型質量分析装置
WO2010107666A1 (en) * 2009-03-17 2010-09-23 Dh Technologies Development Pte. Ltd Ion optics drain for ion mobility
CN101907614B (zh) * 2010-07-26 2012-05-23 中国科学院长春应用化学研究所 超高效液相色谱和质谱联用筛选组织蛋白酶b抑制剂的方法
GB201100301D0 (en) 2011-01-10 2011-02-23 Micromass Ltd Method of processing multidmensional mass spectrometry data

Also Published As

Publication number Publication date
JP2014206497A (ja) 2014-10-30
GB201515881D0 (en) 2015-10-21
CN105122051B (zh) 2017-07-04
GB2527441A (en) 2015-12-23
DE112014001182B4 (de) 2022-03-17
WO2014171390A1 (ja) 2014-10-23
US20160025692A1 (en) 2016-01-28
CN105122051A (zh) 2015-12-02
US10036737B2 (en) 2018-07-31
GB2527441B (en) 2021-02-03
DE112014001182T5 (de) 2015-11-26

Similar Documents

Publication Publication Date Title
JP5997650B2 (ja) 分析システム
CN108982729B (zh) 用于提取质量迹线的系统和方法
JP7325421B2 (ja) Msms信頼度を改良するためのdm-swath取り込み
US11823882B2 (en) Mass correction
EP3155638B1 (en) Analysis of complex biological matrices through targeting and advanced precursor and product ion alignment
US7485853B2 (en) Mass spectrometric mixture analysis
US20170299558A1 (en) Techniques for display and processing of mass spectral data
EP2499655A1 (en) Detection and/or quantification of a compound in a sample
EP4099362A2 (en) Mass spectrometer utilizing mass spectral database search for compound identification
JP4959713B2 (ja) 質量分析計
EP3155639B1 (en) System and method for enhancing charge-state determination in electrospray mass spectrometry
EP3745407A1 (en) Operating a mass spectrometer utilizing a promotion list
EP3355339B1 (en) Detecting low level lcms components by chromatographic reconstruction
CN113574629A (zh) 不可知化合物洗脱测定
US9881776B2 (en) Monitoring liquid chromatography elution to determine when to perform a lockmass calibration
CN111257401B (zh) 用于测定离子种类的质量的系统和方法
CN114616645A (zh) 利用正交碎裂方法的质量分析-swath方法
CN114365258A (zh) 用cid-ecd进行ida的方法
GB2525709A (en) Optimized multiple reaction monitoring or single ion recording method
EP3152778B1 (en) Method to remove ion interferences
CN116324403A (zh) 通过质谱法进行的化合物识别

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20160212

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20160212

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20160816

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20160826

R150 Certificate of patent or registration of utility model

Ref document number: 5997650

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

S531 Written request for registration of change of domicile

Free format text: JAPANESE INTERMEDIATE CODE: R313531

S533 Written request for registration of change of name

Free format text: JAPANESE INTERMEDIATE CODE: R313533

R350 Written notification of registration of transfer

Free format text: JAPANESE INTERMEDIATE CODE: R350