CN105106484A - Medicine for treating sheep flock coccidiosis - Google Patents

Abstract

The invention relates to medicine for treating sheep flock coccidiosis. The medicine comprises, by weight, 30-40 parts of cortex phellodendri, 25-30 parts of radix scutellariae, 15-20 parts of bighead atractylodes rhizome, 20-25 parts of white poria, 15-20 parts of poria with hostwood, 10-15 parts of polyporus umbellatus, 8-10 parts of cassia twig, 15-20 parts of rhizoma alismatis, 5-8 parts of peach kernel, 10-12 parts of raw rhubarb, 5-10 parts of Chinese pulsatilla root, 6-10 parts of liquorice, 4-8 parts of radix dichroa and 0.5-1 part of vitamin K. The medicine has the advantages that Chinese herbal medicine extracted by a percolation method is high in effective component content and good in effect, the medicine has effects of increasing sheep immunity, sterilizing and killing germs, relieving swelling and stopping bleeding, removing heat and diminishing inflammation and improving appetite, symptoms can be relieved after feeding sheep with the medicine for two days, coccidiosis can be cured after feeding the sheep with the medicine for four days, and evident curative effect and low relapse rate are achieved; the medicine does not remain in the sheep or pollute environments due to the fact that the medicine is made of Chinese herbal medicine, and the medicine is convenient in material obtaining and cheap.

Description

A kind of medicament for the treatment of flock of sheep sheep coccidiosis

Technical field

The present invention relates to a kind of medicament, particularly relate to a kind of medicament for the treatment of flock of sheep sheep coccidiosis.

Background technology

Sheep coccidiosis be parasitize sheep or goat by the multiple coccidiosis of Eimeria intestinal epithelial cell in caused by, morbidity can cause acute or chronic enteritis, becomes thin, anemia and dysplasia, and serious caused sheep is only dead, and primary disease is larger to lamb harm.

Sheep infects because of the Sporulated Oocysts of eating coccidiosis, zygoblast invades in enterocyte, first asexual schizogony is carried out, then carry out sexual gametogonia and form egg capsule, egg capsule is discharged extraneous with feces, under suitable temperature, damp condition, complete Sporogony process through 2 ~ 3 days, form Sporulated Oocysts and tool infectivity.The growth of sheep coccidiosis because of kind different, the aspect differences to some extent such as its incubation period, parasitic site, fissiparous algebraically.

Clinical symptoms morbidity according to the Coccidian Species infected, infection intensity, sheep age only, the resistance of body and the difference of feeding and management condition and show acute or chronic process.Acute is more common in the lamb of less than 1 years old.Visible loss of appetite or absolutely useless, lassitude, diarrhoea, is often with blood, stench in feces.Body temperature rises to 40 ~ 41 DEG C sometimes, becomes thin rapidly, anemia, finally dead because of extreme exhaustion.Chronic type performance long-term diarrhea, gradual anemia, becomes thin, hypoevolutism.

Pathological change only small intestinal has obvious pathological changes, and intestinal mucosa is general congested and in mottled, banded hemorrhage, and intestinal mucosa and serosal surface are shown in the foxtail millet grain having quantity not to wait is large to pisiformis pale or yellow coccidiosis tuberosity, normal cluster distributes.Adenomesenteritis enlargement.The heavy damages such as the chorioepithelium lamina propria of small intestinal and gland nest, Intestinal epithelial cells is transparent, degeneration.Visible corpse is become thin, and hind leg and afterbody often have loose stool to pollute.

Current people use a large amount of antibiotic for treating sheep coccidiosis, create certain side effect, easily cause drug residue, and curative effect is not good to the growth of sheep itself.

Summary of the invention

In order to solve the problem, the invention provides a kind of medicament for the treatment of flock of sheep sheep coccidiosis, this medicament not only has good therapeutic effect, and pollution-free, noresidue.

Treat a medicament for flock of sheep sheep coccidiosis, be made up of the material of following weight portion:

30 ~ 40 portions of Cortex Phellodendris, 25 ~ 30 parts of Radix Scutellariaes, 15 ~ 20 parts of Rhizoma Atractylodis Macrocephalaes, 20 ~ 25 parts of Porias, 15 ~ 20 parts of Poria cum Radix Pinis, 10 ~ 15 portions of Polyporus, 8 ~ 10 parts of Ramulus Cinnamomi, 15 ~ 20 portions of Rhizoma Alismatis, 5 ~ 8 parts of Semen Persicaes, 10 ~ 12 parts of Radix Et Rhizoma Rhei, 5 ~ 10 portions of Radix Pulsatillaes, 6 ~ 10 portions of Radix Glycyrrhizaes, 4 ~ 8 parts of Radix Dichroaes, 0.005 ~ 0.01 part of vitamin K;

Its preparation method is as follows:

(1) get 30 ~ 40 portions of Cortex Phellodendris, 25 ~ 30 parts of Radix Scutellariaes, 15 ~ 20 parts of Rhizoma Atractylodis Macrocephalaes, 20 ~ 25 parts of Porias, 15 ~ 20 parts of Poria cum Radix Pinis, 10 ~ 15 parts of Polyporus, 8 ~ 10 parts of Ramulus Cinnamomi, 15 ~ 20 parts of Rhizoma Alismatis, 5 ~ 8 parts of Semen Persicaes, 10 ~ 12 parts of Radix Et Rhizoma Rhei, 5 ~ 10 parts of Radix Pulsatillaes, 6 ~ 10 parts of Radix Glycyrrhizaes, 4 ~ 8 parts of air-dry pulverizing of Radix Dichroae rear mistake 40 orders obtain Chinese medicine powder;

(2) gained Chinese medicine powder is put in percolate pot, carries out percolation operation after adding the alcoholic solution dipping 20 ~ 24h of 75 ~ 80% after compacting evenly again, obtain percolate for subsequent use;

(3) cross 60 orders after being pulverized by 0.005 ~ 0.01 part of vitamin K and add mix homogeneously in gained percolate.

Further, by the sick sheep of feeding after the ratio mixing of this medicament and feedstuff 1:20 by weight when treating sheep coccidiosis.

Composition in the present invention:

Cortex Phellodendri has heat clearing and damp drying, and pathogenic fire purging removes steams, effect of detoxification sore treatment.For damp-heat dysentery, jaundice dark coloured urine, the puckery pain of pyretic stranguria, hectic fever due to YIN-deficiency consumptive fever, eczema eczema.

Radix Scutellariae has the bacterium parasite killing that disappears, heat clearing and damp drying, eliminating fire and detoxication, hemostasis, the effect such as antiabortive.Cure mainly the diseases such as epidemic febrile disease, upper respiratory tract infection, cough due to lung-heat, damp and hot jaundice, pneumonia, dysentery, hemoptysis, conjunctival congestion, frequent fetal movement, hypertension, carbuncle furuncle.

The Rhizoma Atractylodis Macrocephalae has invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive effect, can strengthen sheep body immunity, and has the effect of solution spasm to intestinal smooth.

Poria all has inhibitory action to staphylococcus aureus, escherichia coli, Bacillus proteus etc. and energy mind tranquilizing and the heart calming, and tonifying the lung spleen, controls the deficiency of vital energy.

Poria cum Radix Pini has the functions such as eliminating dampness by diuresis, spleen invigorating, mind calming.For phlegm retention, edema, dysuria, have loose bowels, dizzy.

Polyporus grades containing crude protein 7.89%, ether-soluble extractives 0.24%, crude fibre 46.06%, soluble sugar; Also containing free and conjunction type biotin, 2-hydroxyl-lignoceric acid, biotin, saccharide, protein.There is diuresis, improve the effects such as immunity, anticancer, antidiarrheal.

Ramulus Cinnamomi energy diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation, supporing yang activating QI, dispersing cold for relieving pain.

Rhizoma Alismatis has the effect of hepatoprotective, protection cardiovascular system, hemostasis diuresis.

Semen Persicae has blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation, effect of relieving cough and asthma.

Radix Et Rhizoma Rhei has the effect of attacking stagnant, clearing away damp-heat, pathogenic fire purging, removing heat from blood, blood stasis dispelling, removing toxic substances.

The Radix Pulsatillae has obvious inhibitory action to staphylococcus aureus, bacillus pyocyaneus, anthrax bacillus, Bacillus typhi, alpha streptococcus, group B streptococcus, can be used for treating bleeding.

Radix Glycyrrhizae has treatment inappetence, dyspeptic effect, and has certain antibacterial effect.

Radix Dichroae has vomiting phlegm and saliva by emesis, effect of preventing the attack (or recurrence) of malaria.

Vitamin K has the effect preventing and treating internal hemorrhage and hemorrhoid, the normal freezing of promotion blood.

The present invention has following beneficial effect: the Chinese herbal medicine effective ingredients content that medicament of the present invention is extracted by percolation is high, effective, medicament has raising sheep body immunity, the bacterium parasite killing that disappears, inflation hemostasis, hot antiinflammatory of dispelling, orectic effect, this medicament of feeding gets final product relief of symptoms in two days, within four days, can fully recover, curative effect is remarkable, and relapse rate is low.Again because this medicament is obtained by Chinese herbal medicine, so can not cause residual in sheep body, do not pollute the environment yet, draw materials conveniently, cheap.

Detailed description of the invention

Embodiment 1

Treat a medicament for flock of sheep sheep coccidiosis, be made up of the material of following weight portion:

35 portions of Cortex Phellodendris, 28 parts of Radix Scutellariaes, 20 parts of Rhizoma Atractylodis Macrocephalaes, 23 parts of Porias, 16 parts of Poria cum Radix Pinis, 12 portions of Polyporus, 8 parts of Ramulus Cinnamomi, 15 portions of Rhizoma Alismatis, 6 parts of Semen Persicaes, 10 parts of Radix Et Rhizoma Rhei, 8 portions of Radix Pulsatillaes, 7 portions of Radix Glycyrrhizaes, 4 parts of Radix Dichroaes, 0.006 part of vitamin K;

Its preparation method is as follows:

(1) get 35 portions of Cortex Phellodendris, 28 parts of Radix Scutellariaes, 20 parts of Rhizoma Atractylodis Macrocephalaes, 23 parts of Porias, 16 parts of Poria cum Radix Pinis, 12 parts of Polyporus, 8 parts of Ramulus Cinnamomi, 15 parts of Rhizoma Alismatis, 6 parts of Semen Persicaes, 10 parts of Radix Et Rhizoma Rhei, 8 parts of Radix Pulsatillaes, 7 parts of Radix Glycyrrhizaes, the 4 parts of air-dry pulverizing of Radix Dichroae rear mistake 40 orders obtain Chinese medicine powder;

(2) gained Chinese medicine powder is put in percolate pot, carries out percolation operation after adding the alcoholic solution dipping 22h of 75% after compacting evenly again, obtain percolate for subsequent use;

(3) cross 60 orders after being pulverized by 0.006 part of vitamin K and add mix homogeneously in gained percolate.

Further, by the sick sheep of feeding after the ratio mixing of this medicament and feedstuff 1:20 by weight when treating sheep coccidiosis.

Comparative example 1

Buy the antibiotic medicament of commercially available treatment sheep coccidiosis.

Certain plant is when raising Du Bo goat, find often to be with blood, hyperpyrexia in the young sheep loss of appetite of age in days in 7 ~ August, feces, and solution plane several young sheep find that small intestinals have obvious pathological changes, intestinal mucosa is general congested also in mottled, banded hemorrhage, confirm that flock of sheep infect sheep coccidiosis, immediately 240 ill young sheep are divided equally at random two groups of isolation feedings, one group uses medicament described in embodiment 1, another group uses medicament described in comparative example 1, and following table is two groups of Data Comparisons:

	Embodiment 1	Comparative example 1
			Feeding cures quantity (head) in two days	46	30
Feeding cures quantity (head) in four days	118	90
			Feeding cures quantity (head) in seven days	120	115
Survival rate (%) during feeding seven days	100	98.3
			Relapse rate (%) in feeding 30 days	0	0.8

Table 1.

Embodiment 2

Treat a medicament for flock of sheep sheep coccidiosis, be made up of the material of following weight portion:

35 portions of Cortex Phellodendris, 27 parts of Radix Scutellariaes, 17 parts of Rhizoma Atractylodis Macrocephalaes, 25 parts of Porias, 18 parts of Poria cum Radix Pinis, 13 portions of Polyporus, 8 parts of Ramulus Cinnamomi, 16 portions of Rhizoma Alismatis, 7 parts of Semen Persicaes, 10 parts of Radix Et Rhizoma Rhei, 9 portions of Radix Pulsatillaes, 8 portions of Radix Glycyrrhizaes, 6.5 parts of Radix Dichroaes, 0.008 part of vitamin K.

Embodiment 3

Treat a medicament for flock of sheep sheep coccidiosis, be made up of the material of following weight portion:

34 portions of Cortex Phellodendris, 27 parts of Radix Scutellariaes, 19 parts of Rhizoma Atractylodis Macrocephalaes, 22 parts of Porias, 15 parts of Poria cum Radix Pinis, 14 portions of Polyporus, 8 parts of Ramulus Cinnamomi, 17 portions of Rhizoma Alismatis, 7 parts of Semen Persicaes, 11 parts of Radix Et Rhizoma Rhei, 9 portions of Radix Pulsatillaes, 8.5 portions of Radix Glycyrrhizaes, 6 parts of Radix Dichroaes, 0.01 part of vitamin K.

Claims (3)

1. treat a medicament for flock of sheep sheep coccidiosis, it is characterized in that, be made up of the material of following weight portion:

30 ~ 40 portions of Cortex Phellodendris, 25 ~ 30 parts of Radix Scutellariaes, 15 ~ 20 parts of Rhizoma Atractylodis Macrocephalaes, 20 ~ 25 parts of Porias, 15 ~ 20 parts of Poria cum Radix Pinis, 10 ~ 15 portions of Polyporus, 8 ~ 10 parts of Ramulus Cinnamomi, 15 ~ 20 portions of Rhizoma Alismatis, 5 ~ 8 parts of Semen Persicaes, 10 ~ 12 parts of Radix Et Rhizoma Rhei, 5 ~ 10 portions of Radix Pulsatillaes, 6 ~ 10 portions of Radix Glycyrrhizaes, 4 ~ 8 parts of Radix Dichroaes, 0.005 ~ 0.01 part of vitamin K.

2. a kind of medicament for the treatment of flock of sheep sheep coccidiosis according to claim 1, it is characterized in that, its preparation method is as follows:

(1) get 30 ~ 40 portions of Cortex Phellodendris, 25 ~ 30 parts of Radix Scutellariaes, 15 ~ 20 parts of Rhizoma Atractylodis Macrocephalaes, 20 ~ 25 parts of Porias, 15 ~ 20 parts of Poria cum Radix Pinis, 10 ~ 15 parts of Polyporus, 8 ~ 10 parts of Ramulus Cinnamomi, 15 ~ 20 parts of Rhizoma Alismatis, 5 ~ 8 parts of Semen Persicaes, 10 ~ 12 parts of Radix Et Rhizoma Rhei, 5 ~ 10 parts of Radix Pulsatillaes, 6 ~ 10 parts of Radix Glycyrrhizaes, 4 ~ 8 parts of air-dry pulverizing of Radix Dichroae rear mistake 40 orders obtain Chinese medicine powder;

(2) gained Chinese medicine powder is put in percolate pot, carries out percolation operation after adding the alcoholic solution dipping 20 ~ 24h of 75 ~ 80% after compacting evenly again, obtain percolate for subsequent use;

(3) cross 60 orders after being pulverized by 0.005 ~ 0.01 part of vitamin K and add mix homogeneously in gained percolate.

3. a kind of medicament for the treatment of flock of sheep sheep coccidiosis according to claim 1, is characterized in that, by the sick sheep of feeding after the ratio mixing of this medicament and feedstuff 1:20 by weight during treatment sheep coccidiosis.