CN105106042A - Scalp massaging cream composition capable of strengthening hair roots and consolidating hair - Google Patents
Scalp massaging cream composition capable of strengthening hair roots and consolidating hair Download PDFInfo
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Abstract
The invention provides a scalp massaging cream composition capable of strengthening hair roots and consolidating hair. The scalp massaging cream composition comprises: (A) massaging essential oil accounting for 3.0 to 20.0% of the weight of the composition; (B) a polyoxyethylene group-free non-ionic emulsifier accounting for 1.5 to 5.0% of the weight of the composition; and (C) a hair root follicle activating composition composed of (i) sialic acid accounting for 0.01 to 0.5% of the weight of the composition, (ii) taraxacum mongolicum extract accounting for 0.5 to 5.0% of the weight of the composition, (iii) a heat sensitizer accounting for 0.1 to 1.0% of the weight of the composition, (iv) organic germanium accounting for 0.001 to 0.008% of the weight of the composition and (v) organic zinc accounting for 0.01 to 0.5% of the weight of the composition; with the balance being (D) a water-containing carrier applicable to common cosmetics. The scalp massaging cream composition is applicable to daily scalp care of people with hair dryness, alopecia and hair breakage caused by microcirculation disturbance of hair papillae and stagnant metabolism of hair follicle cells.
Description
Technical field
The present invention relates to a kind of scalp care compositions, the scalp massage dairy compositions of particularly hair follicle root of hair activation.
Background technology
The hair normally come off is all the hair being in catagen and resting stage, and being constantly in dynamic equilibrium owing to entering catagen with the hair newly entering trophophase, therefore can maintaining the hair of normal quantity, is exactly more than normal physiologic alopecia.Pathologic alopecia refers to hair exception or excessive coming off, and its reason is a lot: modal is that stress is excessive, cryptorrhea, body malnutrition and pathobolism.Nervous alopecia be due to stress excessive time, human body arrectores pilorum shrink, hair is upright, vegetative nerve or nervus centralis function get muddled, hair follicle hair papilla changes and malnutrition, thus causes hair growth function inhibitio, and hair enters resting stage and occurs alopecia.Also have trophism alopecia to be the change that body malnutrition and pathobolism may cause hair quality and color development, severe malnutrition causes alopecia generalisata.In a word, physiologic alopecia or common pathologic alopecia all with the metabolism of scalp hair follicles cell and blood circulation closely related.Therefore focus has dry conditioning to transfer to scalp care by hair nursing product.These hair care products are divided into washing-off type and retention type; The drawback of washing-off type care product is that action time is short, not remarkable to effect of scalp care; Existing retention type product then still takes the formula system of hair products on the market, and the zest of its surfactant, conditioner and antiseptic brings side effect.Scalp massage product is then suitable for because of action time and model of action, be more suitable for hair loss patient or.A kind of pure Chinese medicinal anti-hair loss scalp massage cream of CN10416689A application protection, mainly for pathologic alopecia control, its action period is longer.And for the physiological feature of scalp; adopt cosmetics that development of raw materials can be used to meet " cosmetics health specification " safety, instant effect and the scalp massage compositions that has no side effect as the personal daily care product of strong root hair care, the blank in scalp care market can be filled up.
Summary of the invention
The object of this invention is to provide scalp massage compositions, adopt the reasonable combination of chemical-biological activities function raw material and Chinese medicinal plant extract, realize scalp care, hair maintenance effect of activating hair-root hair follicle, strong root hair care.The composition of the chafes such as anion surfactant, cationic surfactant and conditioner that its formula system of scalp massage of the present invention breast is not commonly used containing hair care product.
A scalp massage dairy compositions for strong root hair strengthening, comprises:
(A) the massage quintessence oil of composition weight 3.0% to 20.0% is accounted for;
(B) nonionic emulsifier not containing polyoxyethylene groups of composition weight 1.5% to 5.0% is accounted for;
(C) root of hair hair follicle activated compositions composed of the following components, accounts for the 0.62%-7.0%:(i of composition weight) account for the sialic acid of composition weight 0.01% to 0.5%; (ii) Herba Taraxaci (TARAXACUMMONGOLICUM) the root ethanol extraction of composition weight 0.5% to 5.0% is accounted for; (iii) heat sensitizer of composition weight 0.1% to 1.0% is accounted for; (IV) accounts for the organic germanium of composition weight 0.001% to 0.008%; (V) accounts for the organic zinc of composition weight 0.01% to 0.5%;
(D) surplus is the aqueous carrier of applicable vague generalization cosmetic;
Wherein said massage quintessence oil is that natural virtue treats quintessence oil and plant base oil mixture;
The following formula I of its general structure of described sialic acid:
In formula, R is at least one in galactose, N-acetyl glucosamine, GalNAc, NeuGc ALPHA2-3Gal;
Described heat sensitizer is at least one in Fructus Capsici (CAPSICUMFRUTESCENS) extract, cephrol butyl ether, glycyrrhizic acid dipotassium;
Described organic germanium is Ge-132, and molecular formula is GeCH2COOH;
Described organic zinc is at least one in zinc gluconate, zinc lactate, zinc stearate.
In technical solution of the present invention: it is that Rhizoma Zingiberis Recens folk prescription quintessence oil is or/and Herba thymi vulgaris folk prescription quintessence oil that natural virtue treats quintessence oil, described plant base oil is at least one in American Avocado Tree oil, Jojoba oil, Oleum Vitis viniferae, Semen pruni armeniacae oil, and the volume ratio that natural virtue treats quintessence oil and plant base oil is 2.5:97.5 to 20:80.
Natural virtue treats the composite quintessence oil that quintessence oil can also be ginger essential oil, Geranium Essential, camellia oleosa seed quintessence oil 5:3:3 by volume.
In technical solution of the present invention: the nonionic emulsifier not containing polyoxyethylene groups is at least one in alkyl polyglucoside, sucrose fatty acid ester, polyglyceryl fatty acid ester.
In technical solution of the present invention: alkyl polyglucoside is molecular formula is (C
6o
5h
6)
noR, wherein fatty alcohol carbochain R is C8-C16, and average degree of polymerization n is 1.3-1.6.; Sucrose fatty acid ester general molecular formula is (RCOO)
nc
12h
12o
3(OH)
8-n, the sucrose hydroxyl value n of esterification is 1,2,3; The carbon number of fatty acid alkyl R is 11-17; The general molecular formula of fatty acid glyceride is (C
3h
7o
2)
n-COOR, the polymerization degree n of polyglycereol group is wherein 2-10, and the carbon number of fatty acid alkyl R is 11-17, and the quantity of polyglycereol free hydroxyl group is 5-20 times of fatty acid residue.
In the present invention, sialic acid optimum selection is N-acetyl-neuraminate.
The massage cream compositions of the strong root hair strengthening of the present invention, best component is:
(1) the natural virtue accounting for composition weight 0.075% to 4.0% treats quintessence oil;
(2) the plant base oil of composition weight 2.4% to 19.5% is accounted for;
(3) composition weight 1.5% to 5.0% is accounted for containing at least one in the nonionic emulsifier alkyl polyglucoside of polyoxyethylene groups, sucrose fatty acid ester, polyglyceryl fatty acid ester;
(4) N-acetyl-neuraminate of composition weight 0.01% to 0.5% is accounted for;
(5) Herba Taraxaci (TARAXACUMMONGOLICUM) the root ethanol extraction of composition weight 0.5% to 5.0% is accounted for;
(6) at least one in heat sensitizer Fructus Capsici (CAPSICUMFRUTESCENS) extract of composition weight 0.1% to 1.0%, cephrol butyl ether, glycyrrhizic acid dipotassium is accounted for;
(7) the organic germanium Ge-132 of composition weight 0.001% to 0.008% is accounted for;
(8) at least one in the organic zinc zinc gluconate of composition weight 0.01% to 0.5%, zinc lactate, zinc stearate is accounted for;
(9) surplus is the aqueous carrier of applicable vague generalization cosmetic.
Beneficial effect of the present invention: scalp massage dairy compositions of the present invention is according to scalp physiological structure feature, around the model of action of massage, to invigorate blood circulation effect of skin protection, tough hair quality to massage quintessence oil, in conjunction with the reasonable combination of chemical-biological activities function raw material sialic acid and Chinese medicinal plant extract, and the ageing and sense organ auxiliaring effect of heat sensitizer.Relative to the anti-hair loss products of pure Chinese medicinal preparation, have hair care hair strengthening Be very effective, take effect comparatively faster advantage; And relative to the hormonal medicaments such as minoxidil, finasteride type product for improving hair-growing, then can not produce the side effect of bounce-back after stopping using; Secondly massage cream of the present invention breaks through the conditioner system of hair products completely, compositions does not contain cationic surfactant, the conditioner of scalp irritation and is easy to block the mineral oil of hair follicle, various synthesis silicone oil series, safe to use on scalp or skin, form disposable resident type product, realize maintenance scalp as skin protection.Massage cream of the present invention is cosmetic composition again, meets cosmetics health code requirement, and the product type of massage cream is easy to use, can be used alone and scalp massage instrument also can be coordinated to use.
Detailed description of the invention
To be described in detail to compositional selecting of the present invention and effect below.
The present invention is a kind of scalp root of hair vigor massage cream compositions, comprises: (A) accounts for the massage quintessence oil of composition weight 3.0% to 20.0%; Wherein said massage quintessence oil is natural essential oil and plant base oil mixture; Described natural essential oil is at least one of Rhizoma Zingiberis Recens folk prescription quintessence oil, Herba thymi vulgaris folk prescription quintessence oil; Described natural essential oil is the composite quintessence oil of ginger essential oil, Geranium Essential, cinnamon essential oil 5:3:3 by volume.Quintessence oil is the list-position of particular types plant, as flower, stem, cry, really, root, seed, bark or resin.Extract the plant essence with peat-reek through specific process, great majority are in a liquid state. and be that there is higher volatile organic mixture, be soluble in ethanol, emulsifying agent, fat.This makes them very easily permeate in skin, thus rapid permeability blood capillary arrives each organ in body by blood circulation, and its effective ingredient is by Cell uptake.The remaining composition of quintessence oil can not remain in vivo, its can by urinating, perspire, breathing and being excreted.In addition, natural essential oil also has the effect of killing antibacterial, suppressing flora growth, insect pest.
Quintessence oil in the present invention be have warm property, blood circulation invigorating efficacies natural essential oil if the natural essential oil of ginger essential oil, thyme oil or Bergamot Mint Extract, anti-inflammation and sterilization effect is as Geranium Essential, camellia oleosa seed quintessence oil.Described ginger essential oil is faint yellow to yellow volatile essential oil, there is the distinctive aromatic odor of Rhizoma Zingiberis Recens: eucalyptole (l, 8-cineole), linalool (linalool), geraniol acetate (citronellylacetate), Borneolum Syntheticum (borneol), geranial (geranial) and geraniol (geraniol) are the topmost in fragrant component of fresh ginger fragrance; Relative density (25/25 DEG C): 0.870 ~ 0.882, refraction index (20 DEG C): 1.488 ~ 1.494, optical rotation (20 DEG C) :-28 ° ~-45 °, heavy metal (in Pb)/(mg/kg) :≤10.Described ginger essential oil has antioxidation, and the traditional Chinese medical science confirms to have wind syndrome of head of dispelling, only headache, promotes scalp blood circulation, Anti-hair loss effect.Oneself finds there are 100 various ingredients in oil of ginger, be mainly: sesquiterpene carbohydrate (Sesquiterpenehydrocarbons, account for 50%-66%), next is oxidation sesquiterpene (Oxygenatedsesquiterpenes, account for 17%), remaining is monoterpene class carbohydrate (Monoterpenehydrocarbons) and oxidation monoterpene class (Oxygenatedmonoterpenes) mainly.
The thyme oil that the present invention selects also is yellow volatile essential oil, has fragrant and sweet and strong medicinal herbs taste, and can propagate far away; Its significant physiology curative effect is for stimulating blood circulation, enhancing immunity, activating brain cell; Also be the strongest active inhibiting bacteria and diminishing inflammation quintessence oil simultaneously; Therefore suppress dandruff and suppression to be shaved one's head very effective, be considered to the tonic of scalp.The main active of thyme oil is thymol, linalool, fragrant chaste tree nationality phenol, Borneolum Syntheticum, linalool, nopinene, Flos Caryophylli hydrocarbon; The preferred linalool composition of thyme oil of the present invention is compared with the linalool thyme oil of horn of plenty, and its effect is relatively gentle.
The Geranium Essential that the present invention selects is by distilling floral leaf, and taste slightly like Flos Rosae Rugosae, can be distinguished with lemon, is also that typical virtue treats quintessence oil.Containing citronellol, citronellyl formate, loose alkene, gemic acid, Geraniol, terpineol, citral, menthone and lot of trace mineral element in Geranium Essential.Its major function is to adjust skin, Bergamot Mint Extract, the pore of unimpeded obstruction, blood circulation promoting, is almost applicable to various skin; Effective ingredient in Geranium Essential and natural alicyclic organic have very strong affinity, therefore also have skin clean effect.
The camellia oleosa seed quintessence oil color that the present invention selects is transparent, and volatility is extremely strong, can volatilize, can not cause any harm, namely to the non-stimulated type of skin to tissue if drip in body surface in 24 hours.The topmost chemical composition of camellia oleosa seed quintessence oil is ethylene (terpinene), dipentene (pinene), limonene (limonene), cineol (cineole), Oleum sesami brain (terpineol), anisoxide (cumene) its sterilization effect be the strongest in all quintessence oils, the experiment of Leipzig, Germany university finds, Camellia sinensis effectively can resist 26 kinds of dermatophytes, 32 kinds of Candida albicans and 22 kinds of little sporeformer.
Base oil during the present invention selects is be the non-volatile oils and fats extracted from the seed of plant, flower, rhizome or fruit, Castor Oil skin, can be directly used in skin massage, be also oil at the bottom of the best base of dilution quintessence oil, as American Avocado Tree oil, Jojoba oil, Oleum Vitis viniferae, Semen pruni armeniacae oil.Described plant base oil is containing enriching vitamin composition, mineral, protein; Wherein Oleum Vitis viniferae is comparatively salubrious, is applicable to oiliness skin quality; Semen pruni armeniacae oil, American Avocado Tree oil, dryness in being applicable to, sensitivity skin quality, Jojoba oil is moisturizing more, and all skin quality can be used.
The volume ratio of natural essential oil of the present invention and plant base oil is 2.5:97.5 to 20:80.Namely in massage cream compositions of the present invention, described natural virtue is treated quintessence oil and is accounted for composition weight 0.075% to 4.0%, is good to account for the addition of composition weight 0.5%-2.0%; Described plant base oil accounts for composition weight 2.4% to 19.5%, is good to account for composition weight 5.0%-15%.Natural essential oil composition is very complicated, not only containing the composition useful to human body, and comprises some allergen.Therefore, massage quintessence oil GB GB/T26515-2011 and be recommended as one or more quintessence oils or/and the effective ingredient of absolute oil or this quintessence oil adds appropriate solvent uses together with base oil with antioxidant.
Massage cream compositions of the present invention is also containing the nonionic emulsifier not containing polyoxyethylene backbone accounting for composition weight 1.5% to 5.0%; The wherein said nonionic emulsifier not containing polyoxyethylene groups is at least one in alkyl polyglucoside, sucrose fatty acid ester, polyglyceryl fatty acid ester.
Alkyl polyglucoside (AlkylPolyglycoside) emulsifier molecules formula in the present invention is (C
6o
5h
6)
noR, wherein fatty alcohol carbochain R is C8-C16, and average degree of polymerization n is 1.3-1.6, preferred 1.5-1.6; Alkyl polyglucoside with starch or glucose and natural fatty alcohol for raw material.Obtain through chemosynthesis, fatty alcohol is on average combined with more than one glucose molecule, the average degree of polymerization of this statistical average so-called APG.Described alkyl polyglucoside HLB value changes greatly because the degree of polymerization is different, preferably selects the alkyl polyglucoside product that HLB value is greater than 8.0.Described alkyl polyglucoside can be the APG1214 of Plantacare1200UP, Plantacare2000UP of BASF AG, Shanghai Fa Kai company.Described alkyl polyglucoside bio-toxicity is very little, LD
50=10000 ~ 15000mg/kg, its production process is without the three wastes, and ultimate biodegradation (20 ~ 30 days) is all more than 90%, and environmental sound, can be rated as green surface activity.
Sucrose fatty acid ester emulsifier molecules formula of the present invention is (ROO)
nc
12h
12o
3(OH)
8-nwherein R is the alkyl of fatty acid, and n is the hydroxy esterification number of sucrose; The Ester that on sucrose, 8 OH hydrophilic groups and lipophilic group fatty acid are combined into.Described sucrose fatty acid ester to human body have high safety, to skin and mucosa all non-stimulated, and being easy to biodegradation, is food grade emulsifier.Described sucrose fatty acid ester is according to the kind of fatty acid and esterification degree, colourless to micro-yellow thick gel, soft solid or white to yellowish-brown powder, odorless or micro-smelly.Weak acid, weak base conditional stability, below pH4.2 is unstable, and more than 145 DEG C are easily decomposed, and stablizes for less than 120 DEG C; Sucrose-fatty HLB value 1 ~ 16, wherein monoesters HLB value 10 ~ 16, diester 7 ~ 10, three esters 3 ~ 7.According to the mixed proportion of monoesters to three ester, can be made into the series of products of HLB value 3 ~ 15.Sucrose fatty acid ester of the present invention preferably selects then monoesters or dibasic acid esters, as at least one in sucrose stearate (HLB11,15,19), sucrose palmitate (HLB16), Sucrose myristate (HLB16), Surfhope SE Cosme C 1216 (HLB16), sucrose oleate (HLB15), sucrose distearate (HLB6,8).
Polyglyceryl fatty acid ester molecular formula of the present invention is (C
3h
7o
2)
n-COOR, the polymerization degree n of polyglycereol group is wherein 2-10, fatty acid residue R preferably has the fatty acid residue of 12-18 carbon atom for lauric acid residue, myristic acid residue, oleic acid residues, stearic acid residue, isostearic acid residue etc., the quantity of polyglycereol free hydroxyl group be described fatty acid residue 5-20 times.Preferably for adopting hydrophilic nonionic surfactant, the quantity of free hydroxyl group as above is more than 5 times of the quantity of fatty acid residue, can be: two polyglyceryl laurate (HLB9.2), two polyglyceryl myristate (HLB8.6), three polyglyceryl laurate (HLB9.36), three polyglyceryl myristate (HLB8.94), four polyglycereol monolaurates (HLB10.0), four polyglycerol monooleate (HLB8.0), four polyglycereol monostearates (HLB8.0), five polyglycereol monostearates (HLB11.0), five polyglycereol list isostearates (HLB11.0), six polyglycereol mono laurate fat (HLB13.0), six polyglycerol monooleate (HLB11.0), six polyglycereol monostearates (HLB11.0) ten polyglycereol monostearate (HLB13.5), ten polyglyceryl-isostearate (HLB13.5), ten polyglycerol monooleate (HLB13.0) etc.
(C) root of hair hair follicle activated compositions composed of the following components: (i) accounts for the sialic acid of composition weight 0.01% to 0.5%; (ii) Herba Taraxaci (TARAXACUMMONGOLICUM) root extract of composition weight 0.1% to 1.0% is accounted for; (iii) heat sensitizer of composition weight 0.3% to 1.0% is accounted for; (IV) accounts for the organic germanium of composition weight 0.001% to 0.008%; (V) accounts for the organic zinc of composition weight 0.01% to 0.5%.
The derivant that sialic acid of the present invention (Sialicacids) is gang's neuraminic acid, usually with oligosaccharide, the form of glycolipid or glycoprotein exists, and modal is N-acetyl-neuraminate (N-acetylneuraminicacid, NANA).Namely R is galactose, N-acetyl glucosamine, GalNAc, NeuGc ALPHA2-3Gal, preferred N-acetyl-neuraminate.Germany's common saying " milch cow licks head and controls bald head ", wherein main active and sialic acid in cattle saliva; China also has edible Nidus collocaliae to take good care of the tradition of health, and the main active of Nidus collocaliae is also sialic acid.Sialic acid, for being positioned at glycoprotein side chain terminal, is the important component part of cell membrane surface receptors.At present, sialic acid obtains industrialization by number of ways such as fermentable, enzymatic clarification, chemosynthesis.The EscherichiacoliC-8 fermenting and producing Polysialic acid such as institute of microbiology of Chinese Academy of Sciences Guo Liang, output is 1.200g/L; CN102271535B application protection bacterial fermentation produces sialic method; CN1014668298 then proposes one sialic acid synthetase in plant, realizes the method that industrialization is produced.
Radix Taraxaci extract of the present invention for feverfew Herba Taraxaci TaraxacummongolicumHand.-Mazz., alkali ground Herba Taraxaci TaraxacumsinicumKitag. or can belong to several plants China's Herba Taraxaci (TARAXACUMSINICUM), Europe Herba Taraxaci (TARAXACUMOFFICINALE) root extract together.Adopt to spend spring to autumn when just opening and excavate, removing impurity, cleans, dries, pulverizes; .By feeding intake 1 kilogram, 50% ethanol 2-20L reflux, extract, 3 times, each 1.5 hours; It is 1.13 that outer circulation is evaporated to proportion.Containing multiple health-nutrition compositions such as taraxol, taraxacin, choline, organic acid, inulin in Herba Taraxaci plant, simultaneously containing protein, fat, carbohydrate, trace element and vitamin etc.Radix Taraxaci extract promotes the effect that hepatocyte growth factor HGF produces, and HGF can guide hair follicle to be transformed to trophophase by resting stage, thus activating hair-root hair follicle cell, the effect occurring to send out is educated in display.Radix Taraxaci active component is confirmed as chicoric acid by Amada Co., Ltd. BATHCLIN, and verifies that it has the effect improving the keratin of hair and protein (repetin, tricholhyalin, involucrin) gene expression of hair follicle by molecular biology experiment.
Heat sensitizer of the present invention is at least one in Fructus Capsici (CAPSICUMFRUTESCENS) extract, cephrol butyl ether, glycyrrhizic acid dipotassium.Described heat sensitizer is under the exciting of body temperature, and by shifting the effect of catalyst, physical reactions releases heat.Under the amplification of heat energy, by blood vessel dilating, blood circulation promoting, activating cell, excitor nerve.Described heat sensitizer can provide a kind of instant sensory effects for massage products, improves scalp blood circulation and metabolism, strong root hair strengthening from learning angle and angle of physiology at heart.Wherein Fructus Capsici extract is water-soluble, molten two types of oil, and cephrol butyl ether is that oil is molten, and glycyrrhizic acid dipotassium is water-soluble.Glycyrrhizic acid dipotassium has compatibility widely, can accelerate skin potentiation to their absorption, can be used for sun-proof, assist whitening, antiallergic, antipruritic, regulate sebum, moisturizing and hair-growing and hair care etc.
Organic germanium of the present invention is Ge-132, and molecular formula is GeCH2COOH, and molecular weight is 132.Organic germanium participates in internal metabolism, containing multiple Ge-O key, can catch the hydrogen in metabolite due to his contained negatively charged oxygen atom, play Partial cleansing blood effect; Organic germanium also has hemopoietic stimulation, shows and increases erythrocyte and amount of hemoglobin.
Organic zinc of the present invention is at least one in zinc gluconate, zinc lactate, zinc stearate.Described organic zinc belongs to weak acid and mild base salt together, absorption rate about 14%, is 2 times of inorganic zinc; Zinc is the ingredient of more than 200 kind of enzyme in human organism, participates in the composition of many metalloenzyme in human body; Zinc is that namely regulator gene regulates DNA replication dna, the archaeal dna polymerase of translating and transcribing must form portion, promote root of hair hair follicle cell activating and regenerating.
In massage cream of the present invention, the aqueous carrier being applicable to vague generalization cosmetic comprises appropriate viscosity-controlling agent, wetting agent, chelating agen, pH adjusting agent, antiseptic, pigment etc.Choosing of described antiseptic, essence, pigment, meets the regulation of hygienic standards for cosmetics, selects safe raw material.Described viscosity-controlling agent is carbomer, hydroxyethyl-cellulose, HANSHENGJIAO etc.; Described wetting agent is glycerol, butanediol etc.; Described chelating agen is disodiumedetate, tetrasodium ethylenediamine tetraacetate etc.; Described pH adjusting agent is citric acid, triethanolamine, and pH regulator is 5.0-8.0; Described antiseptic preferred Sensiva SC50 caprylyl glycol compound sensivaSC10, phenoxyethanol Sensiva SC50 compound euxylPE9010.
Using method
Massage cream compositions of the present invention can be used alone and scalp massage instrument also can be coordinated to use, and mainly comprises following step:
(1) with water by hair moistening;
(2) on described hair, use the massage cream compositions of the aforementioned any one claim of effective dose, the scope of described effective dose is generally 5 grams to 50 grams, preferably 10 grams to 20 grams;
(3) with hands or massage instrument, massage 5 minutes to 30 minutes gently along hair direction, until sensation massage cream scalp slight fever, fully absorb.
(4) then massage cream is cleaned with shampoo; Or hair dried by direct dry towel.
These steps can repeatedly repeatedly, to reach effect of sought hair care hair strengthening.
Here is the non-limiting example of elastin composition of the present invention.The providing of these embodiments is only used to the object illustrated, can not be interpreted as limitation of the invention, because without departing from the spirit and scope of the present invention, can carry out many changes to the present invention.In these embodiments, unless stated otherwise, all concentration is all percentage by weight.
Preparation embodiment I-Ⅹ V
Elastin composition of the present invention can by any known or other be effectively applicable to provide the technology of hair setting composition to prepare, the method preparing massage cream compositions of the present invention comprises conventional preparation and hybrid technology.The suitable method preparing massage cream described in embodiment I-Ⅹ V is as follows: suitable quantity of water joined in retort, add emulsifying agent, thickening agent, wetting agent successively, water solublity hair follicle root of hair active component sialic acid, Radix Taraxaci extract, organic germanium, organic zinc, mix homogeneously, this is aqueous phase; In another retort, add plant base oil mix homogeneously, this is oil phase; Then aqueous phase is added in oil phase, add natural fragrant essence, antiseptic, pigment after stirring, stir.
Embodiment I-V
Embodiment VI-Ⅹ
Embodiment Ⅺ-Ⅹ V
Described safety evaluatio method adopts patch test: by 15 embodiment samples and commercially available 2 sections of washing-off type massage product for improving hair-growing S1, S2, issue 30 testers respectively and contrast use.Choose the normal skin of inboard arm.Ready sample is about 25mg to be placed in order in aluminum speckle examination device.Speckle examination thing rehearsal order be from upper → under, also make marks from left → right side.The patch test time is 48 hours, removes speckle examination device observed result after at least 30 minutes: (?)---suspicious reaction; (+)---weak (without bleb) positive reaction; Erythema, infiltration, little erythema may be had; (++);---strong (vesicle) positive reaction; Erythema, infiltration, the non-phlysis of pimple; (+++)---positive reaction extremely; Redness also has bulla; (-)---reactionless; (IR)---dissimilar irritant reaction.
Safety testing result shows that 15 embodiment samples of the present invention are negative reaction, and all weak positive reactions in erythema of commercially available 2 sections of washing-off type massage products.
The animal experiment method of described efficacy assessments is the hair of rejecting 30 mouse backs, and with mice spinal column for boundary, half smears embodiment sample, and half smears commercially available scalp massage product S1; Observe after 4 weeks, according to the original mao state of covering of recovery by significantly to not significantly being recorded as (+++), (++), (+), (±), (-) successively.
Result of the test shows, and only has embodiment I and Ⅺ result not significantly to be recorded as (-), (±) respectively in embodiment I-Ⅹ V; Other embodiments are all recorded as (+) to (+++).
The sensory evaluation method of described efficacy assessments is: 15 embodiments and commercially available scalp massage product S1 are issued respectively 30 testers that alopecia every day amount is greater than 100 and carry out half a head test.Tester uses during massage cream sample and uses according to identical massage time, cleaning method, and often kind of a massage cream uses 8 weeks.Result of use by tested personnel according to suppression alopecia, disconnected send out quantity and strengthen hair toughness effect, and the comfort level of scalp is marked.Standards of grading adopt 7 points of systems, and 0 point completely to no effect, and to no effect, 3-4 portions is effective, and 5-6 divides effective, and 6-7 divides Be very effective for 1-2.
Claims (9)
1. a scalp massage dairy compositions for strong root hair strengthening, comprises:
(A) the massage quintessence oil of composition weight 3.0% to 20.0% is accounted for;
(B) nonionic emulsifier not containing polyoxyethylene groups of composition weight 1.5% to 5.0% is accounted for;
(C) root of hair hair follicle activated compositions composed of the following components, accounts for the 0.62%-7.0%:(i of composition weight) account for the sialic acid of composition weight 0.01% to 0.5%; (ii) Herba Taraxaci (TARAXACUMMONGOLICUM) the root ethanol extraction of composition weight 0.5% to 5.0% is accounted for; (iii) heat sensitizer of composition weight 0.1% to 1.0% is accounted for; (IV) accounts for the organic germanium of composition weight 0.001% to 0.008%; (V) accounts for the organic zinc of composition weight 0.01% to 0.5%;
(D) surplus is the aqueous carrier of applicable vague generalization cosmetic;
Wherein said massage quintessence oil is that natural virtue treats quintessence oil and plant base oil mixture;
The following formula I of its general structure of described sialic acid:
In formula, R is at least one in galactose, N-acetyl glucosamine, GalNAc, NeuGc ALPHA2-3Gal;
Described heat sensitizer is at least one in Fructus Capsici (CAPSICUMFRUTESCENS) extract, cephrol butyl ether, glycyrrhizic acid dipotassium;
Described organic germanium is Ge-132, and molecular formula is GeCH2COOH;
Described organic zinc is at least one in zinc gluconate, zinc lactate, zinc stearate.
2. massage cream compositions according to claim 1, it is that Rhizoma Zingiberis Recens folk prescription quintessence oil is or/and Herba thymi vulgaris folk prescription quintessence oil that wherein said natural virtue treats quintessence oil, described plant base oil is at least one in American Avocado Tree oil, Jojoba oil, Oleum Vitis viniferae, Semen pruni armeniacae oil, and the volume ratio that natural virtue treats quintessence oil and plant base oil is 2.5:97.5 to 20:80.
3. massage cream compositions according to claim 1, wherein said natural virtue treats the composite quintessence oil that quintessence oil is ginger essential oil, Geranium Essential, camellia oleosa seed quintessence oil 5:3:3 by volume.
4. massage cream compositions according to claim 1, the wherein said nonionic emulsifier not containing polyoxyethylene groups is at least one in alkyl polyglucoside, sucrose fatty acid ester, polyglyceryl fatty acid ester.
5. massage cream compositions according to claim 4, wherein said alkyl polyglucoside is molecular formula is (C
6o
5h
6)
noR, wherein fatty alcohol carbochain R is C8-C16, and average degree of polymerization n is 1.3-1.6.
6. massage cream compositions according to claim 4, wherein said sucrose fatty acid ester general molecular formula is (RCOO)
nc
12h
12o
3(OH)
8-n, the sucrose hydroxyl value n of esterification is 1,2,3; The carbon number of fatty acid alkyl R is 11-17.
7. massage cream compositions according to claim 4, the general molecular formula of wherein said polyglyceryl fatty acid ester is (C
3h
7o
2)
n-COOR, the polymerization degree n of polyglycereol group is wherein 2-10, and the carbon number of fatty acid alkyl R is 11-17, and the quantity of polyglycereol free hydroxyl group is 5-20 times of fatty acid residue.
8. massage cream compositions according to claim 1, described sialic acid is N-acetyl-neuraminate.
9. a massage cream compositions for strong root hair strengthening, composed of the following components:
(1) the natural virtue accounting for composition weight 0.075% to 4.0% treats quintessence oil;
(2) the plant base oil of composition weight 2.4% to 19.5% is accounted for;
(3) composition weight 1.5% to 5.0% is accounted for containing at least one in the nonionic emulsifier alkyl polyglucoside of polyoxyethylene groups, sucrose fatty acid ester, polyglyceryl fatty acid ester;
(4) N-acetyl-neuraminate of composition weight 0.01% to 0.5% is accounted for;
(5) Herba Taraxaci (TARAXACUMMONGOLICUM) the root ethanol extraction of composition weight 0.5% to 5.0% is accounted for;
(6) at least one in heat sensitizer Fructus Capsici (CAPSICUMFRUTESCENS) extract of composition weight 0.1% to 1.0%, cephrol butyl ether, glycyrrhizic acid dipotassium is accounted for;
(7) the organic germanium Ge-132 of composition weight 0.001% to 0.008% is accounted for;
(8) at least one in the organic zinc zinc gluconate of composition weight 0.01% to 0.5%, zinc lactate, zinc stearate is accounted for;
(9) surplus is the aqueous carrier of applicable vague generalization cosmetic.
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| CN109044936A (en) * | 2018-10-26 | 2018-12-21 | 广州市白云区大荣精细化工有限公司 | A kind of hair nursing cream and preparation method thereof |
| CN116407460A (en) * | 2021-12-30 | 2023-07-11 | 嘉必优生物技术（武汉）股份有限公司 | Skin external composition and application of sialic acid in preparation of antiallergic preparation |
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| CN109044936A (en) * | 2018-10-26 | 2018-12-21 | 广州市白云区大荣精细化工有限公司 | A kind of hair nursing cream and preparation method thereof |
| CN116407460A (en) * | 2021-12-30 | 2023-07-11 | 嘉必优生物技术（武汉）股份有限公司 | Skin external composition and application of sialic acid in preparation of antiallergic preparation |
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