CN105079030A - Decontamination liquid for protecting human bodies from being burned by chemical substances - Google Patents

Decontamination liquid for protecting human bodies from being burned by chemical substances Download PDF

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Publication number
CN105079030A
CN105079030A CN201410193029.6A CN201410193029A CN105079030A CN 105079030 A CN105079030 A CN 105079030A CN 201410193029 A CN201410193029 A CN 201410193029A CN 105079030 A CN105079030 A CN 105079030A
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CN
China
Prior art keywords
decontamination solution
present
human body
acid
decontamination liquid
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Pending
Application number
CN201410193029.6A
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Chinese (zh)
Inventor
周卫平
唐翔宇
颜邦民
张勇
冉万春
符颖
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CHONGQING CITY CHEMICAL ENGINEERING INST
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CHONGQING CITY CHEMICAL ENGINEERING INST
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Priority to CN201410193029.6A priority Critical patent/CN105079030A/en
Publication of CN105079030A publication Critical patent/CN105079030A/en
Pending legal-status Critical Current

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Abstract

The invention relates to human body decontamination liquid in the field of industrial safety protection. The human body decontamination liquid can protect human bodies from being burned by chemical substances. The human body decontamination liquid comprises chelating agents, sugar, alcohol, complexing agents, univalent metal salt and water. The human body decontamination liquid which is a composition has the advantages that chemical hazardous articles such as acid, alkali, oxidizing agents, reducing agents, complexing agents and solvents can be converted into products which are harmless to the human bodies and environments, and accordingly secondary injury and pollution can be prevented; the composition has merits and potential in the aspects of chemical hazardous article decontamination potency, safety and the like as compared with products with single corrosion-resistant components on markets; the human body decontamination liquid is suitable for emergency protection and rescue during industrial production, so that burning and erosion on the human bodies due to the chemical substances can be relieved.

Description

A kind of decontamination solution of being burnt by chemical substance for protecting human bodies
Technical field
The present invention relates to a kind of for industrial safety protection field human body decontamination solution, be specially adapted to protecting human bodies burn by chemical substance.
Background technology
In modern production with life, people use increasing chemicals.According to statistics, at present at the chemical species of international chemicals protocol registration more than 3,500 ten thousand, and also to increase at a terrific speed.How prevention and corntrol chemicals application risk, and adopting remedial measures, the damage to people brought of reducing risks is that people are devoted to the problem that solves for a long time.In chemical risk, chemical burn is one of risk that is the most common, that the most generally occur.It makes human body molecule, cell or skin histology be subject to stimulation or the corrosion of chemicals, is partly or entirely destroyed.When the eyes of people or contact skin are to having corrosivity or irritating hazardous chemical, chemical burn will be caused.Current chemical burn is reacted by 6 kinds of aggressive chemistry and is caused: chelation and the solution chemical of acid reaction, alkaline reaction, oxidation, reduction, calcium or magnesium react.Once generation chemical burn, to take action as early as possible, make chemicals end at human body.Clean water is used in people's first reaction after generation chemical burn in the past.The chemical substances such as acid, alkali can be removed from human body surface by a large amount of water, thus alleviate infringement degree, prevent third-degree burn.Can say, at this moment water have the effect removing all harmful chemicals, and without any risk.But burn with chemistry in water treatment, its effectiveness is subject to the restriction of two factors.One is the time, must within generation ten second of burning with water cleaning, otherwise, still likely cause injury in various degree.And this condition proves to be difficult to meet in a lot of accident; Two is need a large amount of water, and this just requires after chemical burn occurs, and continue 15 minutes water and rinse.When cold water flush, body temperature rapid drawdown can be caused.In addition, as fruit acid, alkali are splashed into eyes, eyes cannot be opened, and water developing result will be had a greatly reduced quality.So we need a kind of material, the place that burns can either be applied at short notice, well can prevent chemical burn again, this substance spray on skin after, can rapidly and the acid-base reaction of splash on skin, chemical penetration skin can be stoped, with the aminoacid effect in the protein in subcutaneous tissue, the effect of disinfection can also be played.
Summary of the invention
The object of the invention is for overcome the deficiencies in the prior art face provide a kind of for protecting human bodies by chemical substance the decontamination solution of burning, when human body be subject to chemical substance particularly strong acid alkaline matter burn corrode time, the present invention can act on human body and to burn attack sites, to alleviate the burn erosion of chemical substance to human body.
According to a kind of decontamination solution of being burnt by chemical substance for protecting human bodies that the present invention proposes, its feature comprises chelating agen, sugar, alcohol, aminoacid, disinfectant, univalent metal salt and water.The present invention's component is by weight ratio: chelating agen 0.5-20%, sugar 0.2-4%, alcohol 0.2-3%, aminoacid 0.5-7%, chelating agent 0.2-3%, univalent metal salt 0.2-4%, all the other are water, are supplemented to 100%.Chelating agen in proportioning component of the present invention is one or more in TEPA oxalic acid, TEPA triacetic acid or diethylene triamine pentacetic acid (DTPA), plays the effect of reacting with Hazardous Chemical Substances such as acid, alkali, oxidant, reducing agents in decontamination solution of the present invention; Sugar in proportioning component of the present invention is one or both in glucose or sucrose, plays the effect of water suction moisturizing in decontamination solution of the present invention; Alcohol in proportioning component of the present invention is one or both in Polyethylene Glycol or glycerol, plays the effect of adjusting viscosity and water conservation, prevent skin from coming to harm because of dehydration in decontamination solution of the present invention; Disinfectant in proportioning component of the present invention is boric acid, plays sterilization, antibacterial effect in decontamination solution of the present invention; Aminoacid in proportioning component of the present invention is one or more in glutamic acid, cysteine, aspartic acid, glycine or leucine, plays the effect detoxifying and provide nutrition in decontamination solution of the present invention; Univalent metal salt in proportioning component of the present invention is the water soluble salt of potassium or sodium, plays the effect of the osmotic pressure regulating product in decontamination solution of the present invention.By constituent water dissolution in said ratio component, decontamination solution product of the present invention can be obtained through fully mixing.
The present invention has following feature: first, the present invention increases the permeability of decontamination solution by univalent metal salt, the chemical substance corroded into human body can be extracted out in tissue, alleviate strong acid alkaline matter to corrode to the infiltration of tissue, have good repairing effect to human body attack sites of being burnt.The second, chelating agen of the present invention is both sexes chelating agen, can reach multi-point and catch acid, alkali, oxidation, reduction, solvation, chelatropic reaction, eliminates the chemical substance of human body of burning, protection human-body safety.3rd, the present invention not only emergent protection sues and labours effective, and preparation cost is low, is specially adapted to industrial safety protection.4th, stable performance of the present invention, is convenient to backlog control.The present invention is applicable to the emergent protection of chemical substance to human body bum accidents in industrial safety protection field and sues and labours.
Accompanying drawing explanation
The wound surface after 10min is rinsed through chemical burn medicine (enemy fluorine Trane) after Fig. 1 rabbit skin is damaged by concentrated sulphuric acid.
The wound surface after 24h is rinsed through chemical burn medicine (enemy fluorine Trane) after Fig. 2 rabbit skin is damaged by concentrated sulphuric acid.
Fig. 3 rabbit skin is rinsed the wound surface after 10min by after the damage of the NaOH solution of mass concentration 50% through chemical burn medicine (enemy fluorine Trane).
Fig. 4 rabbit skin is rinsed the wound surface after 24h by after the damage of the NaOH solution of mass concentration 50% through chemical burn medicine (enemy fluorine Trane).
The wound surface after 10min is rinsed through decontamination solution obtained in the present invention after Fig. 5 rabbit skin is damaged by concentrated sulphuric acid.
The wound surface after 24h is rinsed through decontamination solution obtained in the present invention after Fig. 6 rabbit skin is damaged by concentrated sulphuric acid.
Fig. 7 rabbit skin is rinsed the wound surface after 10min by after the damage of the NaOH solution of mass concentration 50% through decontamination solution obtained in the present invention.
Fig. 8 rabbit skin is rinsed the wound surface after 24h by after the damage of the NaOH solution of mass concentration 50% through decontamination solution obtained in the present invention.
Fig. 9 decontamination solution and water respectively with 5mlH 2sO 4the corresponding pH change of 0.5mol/L mixing.
Figure 10 decontamination solution and water mix corresponding pH respectively to be changed with 5mlNaOH1mol/L.
Detailed description of the invention
Below in conjunction with embodiment and accompanying drawing, the specific embodiment of the present invention is described in further detail.
According to a kind of decontamination solution of being burnt by chemical substance for protecting human bodies that the present invention proposes, its feature comprises chelating agen, sugar, alcohol, aminoacid, disinfectant, univalent metal salt and water.The present invention's component is by weight ratio: chelating agen 0.5-20%, sugar 0.2-4%, alcohol 0.2-3%, aminoacid 0.5-7%, chelating agent 0.2-3%, univalent metal salt 0.2-4%, all the other are water, are supplemented to 100%.
Embodiment 1 decontamination solution of the present invention is to the cushioning effect of soda acid
(1) decontamination solution of the present invention is to the cushioning effect of strong acid
The H of accurate configuration 0.5mol/l 2sO 4solution.The H of configuration is added respectively in the beaker of 2 50ml 2sO 4solution 5ml, then adds decontamination solution and pure water that 0,5,10,15,20,30ml the present invention obtains respectively, fully measures its pH value after mixing, often criticizes experiment repetition 3 times.
Decontamination solution of the present invention is to H 2sO 4the cushioning effect of solution is in table 1.Result shows, and the decontamination solution that the present invention obtains is to H 2sO 4solution has obvious buffering effect.
The decontamination solution that table 1 the present invention obtains is to H 2sO 4the cushioning effect of solution
(2) decontamination solution of the present invention is to the cushioning effect of highly basic
The NaOH solution of accurate configuration 1.0mol/l.In the beaker of 2 50ml, add the NaOH solution 5ml of configuration respectively, then add decontamination solution and pure water that 0,5,10,15,20,30ml the present invention obtains respectively, fully measure its pH value after mixing, often criticize experiment repetition 3 times.
The decontamination solution that the present invention obtains to the cushioning effect of NaOH solution in table 2.Result shows, and the decontamination solution that the present invention obtains has obvious buffering effect to NaOH solution.
The decontamination solution that table 2 the present invention obtains is to the cushioning effect of NaOH solution
Embodiment 2 skin irritation test
Rabbit: 8, male and female half and half, body weight 1.5-2.5Kg.
Observe the irritation effect of decontamination solution of the present invention to rabbit intact skin and damaged skin.Erythema and edema judgment criteria are carried out according to " skin irritation reaction scoring and the skin irritation intensity " in " the clinical front guideline compilation of new drug ".
Result shows, decontamination solution of the present invention to no skin irritation in table 3.
Table 3 rabbit skin irritation test result
Embodiment 3 animal skin decontaminating effect is tested
(1) preparation of decontamination solution
Decontamination solution weight proportion is: TEPA oxalic acid 7%, glucose 1%, Polyethylene Glycol 0.3%, glycerol 1.5%, boric acid 0.4%, glutamic acid 0.3%, cysteine 1.5%, aspartic acid 0.5%, sodium chloride 1%, water 86.5%.Decontamination solution pH value is 6.5.
(2) decontaminating effect test
Rabbit test antedorsal unhairing, then be attached on the exposed skin of a rabbit back with the filter paper soaking concentrated sulphuric acid and sodium hydroxide solution respectively, after being detained 30s, rinse burned skin respectively with same speed with decontamination solution of the present invention and chemical burn medicine (enemy fluorine Trane), the wound healing actual effect contrast of burned skin refers to photo schematic diagram.Result shows: decontamination solution of the present invention all has good protective effect to skin acid damage, and burn wound is little, and healing is very fast, effective.Decontamination solution of the present invention has the decontamination effect suitable with chemical burn medicine (opposing fluorine Trane).
Fig. 1 rinses the wound surface after 10min through chemical burn medicine (enemy fluorine Trane) after rabbit skin is damaged by concentrated sulphuric acid, and wound tissue is without the phenomenon of damage further;
Fig. 2 rinses the wound surface after 24h through chemical burn medicine (enemy fluorine Trane) after rabbit skin is damaged by concentrated sulphuric acid, and decontamination wound surface area reduces, and healing in order;
Fig. 3 is that rabbit skin is rinsed the wound surface after 10min by after the damage of the NaOH solution of mass concentration 50% through chemical burn medicine (enemy fluorine Trane), and wound tissue is without the phenomenon of damage further;
Fig. 4 is that rabbit skin is rinsed the wound surface after 24h by after the damage of the NaOH solution of mass concentration 50% through chemical burn medicine (enemy fluorine Trane), and decontamination wound surface area reduces, and healing in order;
Fig. 5 rinses the wound surface after 10min through decontamination solution of the present invention after rabbit skin is damaged by concentrated sulphuric acid, and wound tissue is without the phenomenon of damage further;
Fig. 6 rinses the wound surface after 24h through decontamination solution of the present invention after rabbit skin is damaged by concentrated sulphuric acid, and decontamination wound surface area reduces, healing in order, its effect and chemical burn medicine (opposing fluorine Trane) similar;
Fig. 7 is that rabbit skin is rinsed the wound surface after 10min by after the damage of the NaOH solution of mass concentration 50% through decontamination solution of the present invention, and wound tissue is without the phenomenon of damage further;
To be rabbit skin rinsed the wound surface after 24h by after the damage of the NaOH solution of mass concentration 50% through decontamination solution of the present invention to Fig. 8, and decontamination wound surface area reduces, healing in order, its effect and chemical burn medicine (opposing fluorine Trane) similar.
The present invention, through experimental verification repeatedly, achieves satisfied effect.

Claims (8)

1., for the decontamination solution that protecting human bodies is burnt by chemical substance, its feature comprises chelating agen, sugar, alcohol, aminoacid, disinfectant, univalent metal salt and water.
2. decontamination solution according to claim 1, it is characterized in that the composition by weight of proportioning is: chelating agen 0.5-20%, sugar 0.2-4%, alcohol 0.2-3%, aminoacid 0.5-7%, chelating agent 0.2-3%, univalent metal salt 0.2-4%, all the other for water, be supplemented to 100%.
3. the decontamination solution according to right 1,2, is characterized in that chelating agen is one or more in TEPA oxalic acid, TEPA triacetic acid or diethylenetriamine triacetic acid.
4. the decontamination solution according to right 1,2, is characterized in that sugar is for one or both in glucose or sucrose.
5. the decontamination solution according to right 1,2, is characterized in that alcohol is one or both in Polyethylene Glycol or glycerol.
6. the decontamination solution according to right 1,2, is characterized in that disinfectant is boric acid.
7. the decontamination solution according to right 1,2, is characterized in that aminoacid is one or more in glutamic acid, cysteine, aspartic acid, glycine or leucine.
8. the decontamination solution according to right 1,2, is characterized in that univalent metal salt is the water soluble salt of potassium or sodium.
CN201410193029.6A 2014-05-08 2014-05-08 Decontamination liquid for protecting human bodies from being burned by chemical substances Pending CN105079030A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201410193029.6A CN105079030A (en) 2014-05-08 2014-05-08 Decontamination liquid for protecting human bodies from being burned by chemical substances

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201410193029.6A CN105079030A (en) 2014-05-08 2014-05-08 Decontamination liquid for protecting human bodies from being burned by chemical substances

Publications (1)

Publication Number Publication Date
CN105079030A true CN105079030A (en) 2015-11-25

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106214686A (en) * 2016-07-01 2016-12-14 吉林大学珠海学院 A kind of bionical tissue fluid with resist chemical
CN107343873A (en) * 2016-05-05 2017-11-14 王雷雷 It is a kind of to be used to alleviate cleaning fluid of hydrofluoric acid burn and preparation method thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107343873A (en) * 2016-05-05 2017-11-14 王雷雷 It is a kind of to be used to alleviate cleaning fluid of hydrofluoric acid burn and preparation method thereof
CN107343873B (en) * 2016-05-05 2020-09-01 王雷雷 Cleaning liquid for relieving hydrofluoric acid burn and preparation method thereof
CN106214686A (en) * 2016-07-01 2016-12-14 吉林大学珠海学院 A kind of bionical tissue fluid with resist chemical

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Application publication date: 20151125

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