CN105077275A - Shark cartilage powder calcium-supplement capsule for children - Google Patents
Shark cartilage powder calcium-supplement capsule for children Download PDFInfo
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- CN105077275A CN105077275A CN201510433069.8A CN201510433069A CN105077275A CN 105077275 A CN105077275 A CN 105077275A CN 201510433069 A CN201510433069 A CN 201510433069A CN 105077275 A CN105077275 A CN 105077275A
- Authority
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- China
- Prior art keywords
- shark cartilage
- parts
- capsule
- cartilage powder
- spirulina
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- 241000251730 Chondrichthyes Species 0.000 title claims abstract description 48
- 239000002775 capsule Substances 0.000 title claims abstract description 47
- 210000000845 cartilage Anatomy 0.000 title claims abstract description 47
- 239000000843 powder Substances 0.000 title claims abstract description 42
- 229940069978 calcium supplement Drugs 0.000 title abstract 4
- 210000004080 milk Anatomy 0.000 claims abstract description 19
- 235000013336 milk Nutrition 0.000 claims abstract description 19
- 235000016425 Arthrospira platensis Nutrition 0.000 claims abstract description 18
- 240000002900 Arthrospira platensis Species 0.000 claims abstract description 18
- 239000008267 milk Substances 0.000 claims abstract description 18
- 239000002994 raw material Substances 0.000 claims abstract description 18
- 229940082787 spirulina Drugs 0.000 claims abstract description 18
- 230000001954 sterilising effect Effects 0.000 claims abstract description 11
- 239000011575 calcium Substances 0.000 claims description 33
- 229910052791 calcium Inorganic materials 0.000 claims description 31
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims description 29
- 244000144725 Amygdalus communis Species 0.000 claims description 16
- 235000011437 Amygdalus communis Nutrition 0.000 claims description 16
- 235000020224 almond Nutrition 0.000 claims description 16
- 239000000203 mixture Substances 0.000 claims description 11
- GUTLYIVDDKVIGB-OUBTZVSYSA-N Cobalt-60 Chemical compound [60Co] GUTLYIVDDKVIGB-OUBTZVSYSA-N 0.000 claims description 5
- 238000004140 cleaning Methods 0.000 claims description 5
- 238000002372 labelling Methods 0.000 claims description 5
- 238000010298 pulverizing process Methods 0.000 claims description 5
- 230000000694 effects Effects 0.000 abstract description 6
- 238000000034 method Methods 0.000 abstract description 3
- 241000512259 Ascophyllum nodosum Species 0.000 abstract 2
- 235000009827 Prunus armeniaca Nutrition 0.000 abstract 2
- 244000018633 Prunus armeniaca Species 0.000 abstract 2
- 238000002156 mixing Methods 0.000 abstract 2
- 230000002195 synergetic effect Effects 0.000 abstract 1
- 230000037182 bone density Effects 0.000 description 5
- 238000012360 testing method Methods 0.000 description 5
- 239000008280 blood Substances 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 3
- 150000001669 calcium Chemical class 0.000 description 3
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 230000007674 genetic toxicity Effects 0.000 description 2
- 231100000025 genetic toxicology Toxicity 0.000 description 2
- 150000004676 glycans Chemical class 0.000 description 2
- 229920001282 polysaccharide Polymers 0.000 description 2
- 239000005017 polysaccharide Substances 0.000 description 2
- SQDAZGGFXASXDW-UHFFFAOYSA-N 5-bromo-2-(trifluoromethoxy)pyridine Chemical compound FC(F)(F)OC1=CC=C(Br)C=N1 SQDAZGGFXASXDW-UHFFFAOYSA-N 0.000 description 1
- 206010002383 Angina Pectoris Diseases 0.000 description 1
- 229920001287 Chondroitin sulfate Polymers 0.000 description 1
- 102000010834 Extracellular Matrix Proteins Human genes 0.000 description 1
- 108010037362 Extracellular Matrix Proteins Proteins 0.000 description 1
- 229920002683 Glycosaminoglycan Polymers 0.000 description 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 1
- 208000004550 Postoperative Pain Diseases 0.000 description 1
- 230000003187 abdominal effect Effects 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 231100000460 acute oral toxicity Toxicity 0.000 description 1
- 230000004075 alteration Effects 0.000 description 1
- 230000002460 anti-migrenic effect Effects 0.000 description 1
- 230000000259 anti-tumor effect Effects 0.000 description 1
- 230000000840 anti-viral effect Effects 0.000 description 1
- 230000010100 anticoagulation Effects 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 210000003321 cartilage cell Anatomy 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 230000008131 children development Effects 0.000 description 1
- 229940059329 chondroitin sulfate Drugs 0.000 description 1
- 208000029078 coronary artery disease Diseases 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 210000002744 extracellular matrix Anatomy 0.000 description 1
- 235000013402 health food Nutrition 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 210000000987 immune system Anatomy 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- 239000002398 materia medica Substances 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 231100000682 maximum tolerated dose Toxicity 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 231100000350 mutagenesis Toxicity 0.000 description 1
- 238000002703 mutagenesis Methods 0.000 description 1
- 208000010125 myocardial infarction Diseases 0.000 description 1
- 208000004296 neuralgia Diseases 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 239000011574 phosphorus Substances 0.000 description 1
- 229910052698 phosphorus Inorganic materials 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 230000001172 regenerating effect Effects 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 231100000820 toxicity test Toxicity 0.000 description 1
- 238000009602 toxicology test Methods 0.000 description 1
- 210000000623 ulna Anatomy 0.000 description 1
- 235000020795 whole food diet Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/152—Milk preparations; Milk powder or milk powder preparations containing additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention discloses a shark cartilage powder calcium-supplement capsule for children. The capsule is prepared from the following raw materials in parts by mass: 30-50 parts of shark cartilage powder, 10-15 parts of apricot kernels, 5-10 parts of kelp, 3-5 parts of spirulina and 20-30 parts of fresh milk by a process of blending, mixing, sterilizing and filling capsules. The shark cartilage powder calcium-supplement capsule can be used for remarkably improving the effect of calcium supplement for children by means of the synergetic effect among the shark cartilage powder, apricot kernels, kelp, spirulina and fresh milk, is safe, does not have side effect, is convenient to eat, and has a good market application prospect.
Description
Technical field
The present invention relates to a kind of child form shark cartilage powder calcium compensation capsule, particularly a kind of take shark cartilage powder as the calcium compensation capsule that raw material is made, and belongs to field of health care food.
Background technology
Shark is one of ancient, the most long-lived in the world deep-sea marine organisms, and survived on earth 400,000,000 years, it has improves immune system, vitality is extremely strong, infected by the disease hardly, even if be subject to wound, wound also can restore very soon, and the cancered probability of shark is about 1,/00 ten thousand.China shark is medicinal first appeared in Collective Notes to the Canon of Materia medica, its cartilage is formed primarily of cartilage cell with containing collagenous fibres and a large amount of proteoglycan and extracellular matrix, and the polysaccharide extracted from Shark cartilage is mainly used in treatment neuralgia, antimigraine, abdominal postoperative pain etc. clinically.In Europe, the United States, Deng developed country, Shark cartilage polysaccharide as health food or health medicine prolonged application in disease such as control coronary heart diseases and angina pectoris, myocardial infarction etc., without obvious toxic and side effect.Recent study shows in Shark cartilage except being rich in the mineral matters such as calcium, phosphorus, magnesium, and also containing multiple mucopolysaccharide and chondroitin sulfate, having significant anticoagulation, reducing blood lipid, the function such as antiviral and antitumor, is rare wholefood resource.Promote human body regenerating bone or cartilage because shark cartilage powder possesses, suppress the innate efficacy of new vessels, therefore shark cartilage powder is a kind of excellent raw material of replenishing the calcium.
Summary of the invention
For overcoming the deficiencies in the prior art, the object of the present invention is to provide a kind of child form shark cartilage powder calcium compensation capsule.
Above-mentioned purpose of the present invention is achieved by the following technical programs:
The invention provides a kind of child form shark cartilage powder calcium compensation capsule, it is characterized in that calcium compensation capsule raw material composition and quality proportioning are: shark cartilage powder 30 ~ 50 parts, 10 ~ 15 parts, almond, 5 ~ 10 parts, sea-tangle, spirulina 3 ~ 5 parts, fresh milk 20 ~ 30 parts.
The invention provides a kind of child form shark cartilage powder calcium compensation capsule, it is characterized in that being prepared by following steps:
(1) prepare burden: shark cartilage powder, almond, sea-tangle, spirulina, fresh milk are prepared burden according to the above ratio;
(2) pulverize: shark cartilage powder, almond, sea-tangle, the mixed superminiature pulverizer of spirulina are pulverized, crosses 200 mesh sieves;
(3) mix: the raw material milk after pulverizing is mixed, mixture homogeneity >=95%;
(4) dry: mixed raw material is dried to constant weight in microwave vacuum dryer;
(5) sterilizing: with cobalt-60 sterilizing;
(6) filling capsule: filling at indoor No. 0 capsule of cleaning;
(7) shaped article: bottled by the capsule after filling, labeling, namely coding obtains child form shark cartilage powder calcium compensation capsule.
The invention provides a kind of child form shark cartilage powder calcium compensation capsule, carried out toxicology test and the safety evaluatio of calcium compensation capsule by animal experiment.Chmice acute Oral toxicity result of the test shows, this calcium compensation capsule is greater than high dose group 75mg/kgbw to chmice acute per os maximum tolerated dose; Genetic toxicity test mouse marrow cell micro nuclear test and mouse inbred strain two result of the tests are feminine gender, show that this calcium compensation capsule is without mutagenesis; From rat 30d feeding trial, the behavior of rat sign is normal, figure is healthy, blood and blood parameters also change without exception, and therefore the dosage (150 times of human body recommended amounts) of 75mg/kgbw belongs to safe dose; Genetic toxicity test and rat 30d feeding trial result are feminine gender, therefore determine that this calcium compensation capsule belongs to non-toxic type food, and people can be safe relieved edible.
The invention provides a kind of child form shark cartilage powder calcium compensation capsule, it is advantageous that the synergy each other of scientific compatibility shark cartilage powder and multiple raw material of replenishing the calcium, can play is fast effect that children replenish the calcium.There is complicated interaction relationship by Chinese herbal medicines such as shark cartilage powder and almond, sea-tangle, spirulina, fresh milks in the application, rational proportion, achieves unforeseeable technique effect, makes the relation generation material alterations of calcium compensation capsule to each other.Measure calcium compensation capsule and the single impact of raw material on upgrowth and development of children and bone density of replenishing the calcium, height after result shows edible Ca-containing capsule, upgrading amount, sitting height index are significantly higher than single raw material and replenish the calcium group, significant difference (P<0.01); The bone density of two groups of students, radius mean breadth, BMC are all in normal range (NR), but the mean bone density of edible Ca-containing Capsules group, radius mean bone density and ulna mean bone density are significantly higher than simple drink milk group (P<0.01), illustrate that calcium compensation capsule of the present invention significantly can promote child development, shark cartilage powder and other synergies of replenishing the calcium between raw material serve the effect of " 1+1>2 ".
Detailed description of the invention
Below in conjunction with embodiment, the present invention will be further described.
embodiment 1:
A kind of child form shark cartilage powder calcium compensation capsule, prepared by following steps:
(1) prepare burden: by shark cartilage powder, almond, sea-tangle, spirulina, fresh milk in shark cartilage powder 40 parts, 12 parts, almond, 8 parts, sea-tangle, spirulina 4 parts, fresh milk 25 parts of ratio batchings;
(2) pulverize: shark cartilage powder, almond, sea-tangle, the mixed superminiature pulverizer of spirulina are pulverized, crosses 200 mesh sieves;
(3) mix: the raw material milk after pulverizing is mixed, mixture homogeneity >=95%;
(4) dry: mixed raw material is dried to constant weight in microwave vacuum dryer;
(5) sterilizing: with cobalt-60 sterilizing;
(6) filling capsule: filling at indoor No. 0 capsule of cleaning;
(7) shaped article: bottled by the capsule after filling, labeling, namely coding obtains child form shark cartilage powder calcium compensation capsule.
embodiment 2:
A kind of child form shark cartilage powder calcium compensation capsule, prepared by following steps:
(1) prepare burden: by shark cartilage powder, almond, sea-tangle, spirulina, fresh milk in shark cartilage powder 50 parts, 10 parts, almond, 10 parts, sea-tangle, spirulina 3 parts, fresh milk 30 parts of ratio batchings;
(2) pulverize: shark cartilage powder, almond, sea-tangle, the mixed superminiature pulverizer of spirulina are pulverized, crosses 200 mesh sieves;
(3) mix: the raw material milk after pulverizing is mixed, mixture homogeneity >=95%;
(4) dry: mixed raw material is dried to constant weight in microwave vacuum dryer;
(5) sterilizing: with cobalt-60 sterilizing;
(6) filling capsule: filling at indoor No. 0 capsule of cleaning;
(7) shaped article: bottled by the capsule after filling, labeling, namely coding obtains child form shark cartilage powder calcium compensation capsule.
embodiment 3:
A kind of child form shark cartilage powder calcium compensation capsule, prepared by following steps:
(1) prepare burden: by shark cartilage powder, almond, sea-tangle, spirulina, fresh milk in shark cartilage powder 30 parts, 15 parts, almond, 5 parts, sea-tangle, spirulina 5 parts, fresh milk 20 parts of ratio batchings;
(2) pulverize: shark cartilage powder, almond, sea-tangle, the mixed superminiature pulverizer of spirulina are pulverized, crosses 200 mesh sieves;
(3) mix: the raw material milk after pulverizing is mixed, mixture homogeneity >=95%;
(4) dry: mixed raw material is dried to constant weight in microwave vacuum dryer;
(5) sterilizing: with cobalt-60 sterilizing;
(6) filling capsule: filling at indoor No. 0 capsule of cleaning;
(7) shaped article: bottled by the capsule after filling, labeling, namely coding obtains child form shark cartilage powder calcium compensation capsule.
Above embodiment only for illustration of technical scheme of the present invention, but not is limited; Although be described in detail by invention with reference to previous embodiment, for the person of ordinary skill of the art, still the technical scheme described in previous embodiment can be modified, or equivalent replacement has been carried out to wherein portion of techniques feature; And to these amendments or replacement, do not make the essence of appropriate technical solution depart from the spirit and scope of the present invention's technical scheme required for protection.
Claims (1)
1. a child form shark cartilage powder calcium compensation capsule, is characterized in that being prepared by following steps:
(1) prepare burden: by shark cartilage powder, almond, sea-tangle, spirulina, fresh milk in shark cartilage powder 30 ~ 50 parts, 10 ~ 15 parts, almond, 5 ~ 10 parts, sea-tangle, spirulina 3 ~ 5 parts, fresh milk 20 ~ 30 parts of ratio batchings;
(2) pulverize: shark cartilage powder, almond, sea-tangle, the mixed superminiature pulverizer of spirulina are pulverized, crosses 200 mesh sieves;
(3) mix: the raw material milk after pulverizing is mixed, mixture homogeneity >=95%;
(4) dry: mixed raw material is dried to constant weight in microwave vacuum dryer;
(5) sterilizing: with cobalt-60 sterilizing;
(6) filling capsule: filling at indoor No. 0 capsule of cleaning;
(7) shaped article: bottled by the capsule after filling, labeling, namely coding obtains child form shark cartilage powder calcium compensation capsule.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510433069.8A CN105077275A (en) | 2015-07-22 | 2015-07-22 | Shark cartilage powder calcium-supplement capsule for children |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510433069.8A CN105077275A (en) | 2015-07-22 | 2015-07-22 | Shark cartilage powder calcium-supplement capsule for children |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105077275A true CN105077275A (en) | 2015-11-25 |
Family
ID=54559322
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510433069.8A Pending CN105077275A (en) | 2015-07-22 | 2015-07-22 | Shark cartilage powder calcium-supplement capsule for children |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105077275A (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1272366A (en) * | 1999-04-30 | 2000-11-08 | 尹渭元 | Shark calcium tablet |
| CN101317684A (en) * | 2007-06-08 | 2008-12-10 | 张文彪 | Solid beverage and preparation method there of |
-
2015
- 2015-07-22 CN CN201510433069.8A patent/CN105077275A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1272366A (en) * | 1999-04-30 | 2000-11-08 | 尹渭元 | Shark calcium tablet |
| CN101317684A (en) * | 2007-06-08 | 2008-12-10 | 张文彪 | Solid beverage and preparation method there of |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20151125 |
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| RJ01 | Rejection of invention patent application after publication |