CN105073179B - 经皮药物递送装置 - Google Patents

经皮药物递送装置 Download PDF

Info

Publication number
CN105073179B
CN105073179B CN201480009137.1A CN201480009137A CN105073179B CN 105073179 B CN105073179 B CN 105073179B CN 201480009137 A CN201480009137 A CN 201480009137A CN 105073179 B CN105073179 B CN 105073179B
Authority
CN
China
Prior art keywords
drug delivery
reservoir
delivery device
transdermal drug
skin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201480009137.1A
Other languages
English (en)
Chinese (zh)
Other versions
CN105073179A (zh
Inventor
R·F·罗斯
L·哈根
A·马尔金
D·哈切特
J·马克斯
T·卢茨欧
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sorrento Therapeutics Inc
Original Assignee
Kimberly Clark Worldwide Inc
Sorrento Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kimberly Clark Worldwide Inc, Sorrento Therapeutics Inc filed Critical Kimberly Clark Worldwide Inc
Priority to CN201910125304.3A priority Critical patent/CN109621083B/zh
Publication of CN105073179A publication Critical patent/CN105073179A/zh
Application granted granted Critical
Publication of CN105073179B publication Critical patent/CN105073179B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142Pressure infusion, e.g. using pumps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142Pressure infusion, e.g. using pumps
    • A61M5/14244Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142Pressure infusion, e.g. using pumps
    • A61M5/14244Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14248Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/158Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/42Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for desensitising skin, for protruding skin to facilitate piercing, or for locating point where body is to be pierced
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/42Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for desensitising skin, for protruding skin to facilitate piercing, or for locating point where body is to be pierced
    • A61M5/425Protruding skin to facilitate piercing, e.g. vacuum cylinders, vein immobilising means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142Pressure infusion, e.g. using pumps
    • A61M5/14244Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14248Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
    • A61M2005/14252Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type with needle insertion means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/158Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
    • A61M2005/1587Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body suitable for being connected to an infusion line after insertion into a patient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023Drug applicators using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046Solid microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0061Methods for using microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Medical Informatics (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
CN201480009137.1A 2013-02-28 2014-02-28 经皮药物递送装置 Active CN105073179B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201910125304.3A CN109621083B (zh) 2013-02-28 2014-02-28 药物递送装置

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361770639P 2013-02-28 2013-02-28
US61/770639 2013-02-28
PCT/IB2014/059345 WO2014132240A1 (en) 2013-02-28 2014-02-28 Transdermal drug delivery device

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN201910125304.3A Division CN109621083B (zh) 2013-02-28 2014-02-28 药物递送装置

Publications (2)

Publication Number Publication Date
CN105073179A CN105073179A (zh) 2015-11-18
CN105073179B true CN105073179B (zh) 2019-03-19

Family

ID=51427583

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201480009137.1A Active CN105073179B (zh) 2013-02-28 2014-02-28 经皮药物递送装置
CN201910125304.3A Active CN109621083B (zh) 2013-02-28 2014-02-28 药物递送装置

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201910125304.3A Active CN109621083B (zh) 2013-02-28 2014-02-28 药物递送装置

Country Status (11)

Country Link
US (3) US10183156B2 (enExample)
EP (1) EP2961471B1 (enExample)
JP (2) JP6522523B2 (enExample)
KR (3) KR102370538B1 (enExample)
CN (2) CN105073179B (enExample)
AU (1) AU2014222308B2 (enExample)
BR (1) BR112015020328B1 (enExample)
CA (1) CA2901568C (enExample)
MX (1) MX360121B (enExample)
RU (1) RU2622605C2 (enExample)
WO (1) WO2014132240A1 (enExample)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3247262A1 (en) * 2015-01-23 2017-11-29 Marcio Marc Abreu Apparatus and method for skin treatment
PL3325080T3 (pl) 2015-07-24 2022-01-24 Sorrento Therapeutics, Inc. Sposoby lepszego dostarczania środków czynnych do guzów
CN107949418B (zh) 2015-07-24 2024-07-02 索伦托治疗有限公司 用于活性剂的淋巴递送的方法
EP3395397B1 (en) * 2015-12-21 2022-10-12 Medrx Co., Ltd. Microneedle patch applicator housing
KR101672671B1 (ko) * 2016-03-03 2016-11-03 김경원 석션 니들 부재와 결합되는 환형 밀착캡을 갖는 오토 인젝터 핸드피스
JP6726512B2 (ja) * 2016-03-31 2020-07-22 コスメディ製薬株式会社 マイクロニードルアプリケータ
EP3831438B8 (en) * 2016-04-29 2025-02-19 Vivasor, Inc. Microneedle array assembly
WO2018017196A1 (en) * 2016-07-18 2018-01-25 Siemens Healthcare Diagnostics Inc. Biofouling prevention of wearable sensors and methods of use and calibration related thereto
KR101933767B1 (ko) * 2016-09-05 2018-12-28 (의료)길의료재단 발기부전 환자를 위한 콘돔
WO2018056584A1 (ko) 2016-09-21 2018-03-29 삼성전자 주식회사 피부 상태 측정 방법 및 이를 위한 전자 장치
EP3544658B1 (en) 2016-11-22 2024-07-03 LTS Device Technologies Ltd Apparatus for delivering a therapeutic substance
WO2018132430A1 (en) * 2017-01-10 2018-07-19 A.T. Still Universiy Fluid infusion system
JP6931217B2 (ja) * 2017-03-28 2021-09-01 コスメディ製薬株式会社 水溶性シート状製剤のアプリケータ
IL301683B2 (en) 2017-05-17 2025-02-01 Massachusetts Inst Technology Self-healing systems and related components and methods
US11541015B2 (en) 2017-05-17 2023-01-03 Massachusetts Institute Of Technology Self-righting systems, methods, and related components
USD895109S1 (en) * 2017-10-18 2020-09-01 Roche Diabetes Care, Inc. Inserter for an infusion set
CN109718421B (zh) * 2017-10-27 2022-04-29 研能科技股份有限公司 穿戴式人体胰岛素注入供液装置
EP3793667A1 (en) 2018-05-17 2021-03-24 Massachusetts Institute of Technology Systems for electrical stimulation
EP3603489A1 (fr) * 2018-08-03 2020-02-05 PKvitality Système de surveillance corporelle avec liaison séparable
WO2020069569A1 (en) * 2018-10-02 2020-04-09 WearOptimo Pty Ltd Actuator system
EP3632487B1 (en) 2018-10-05 2024-06-12 LTS Device Technologies Ltd Triggering sequence
DE102019200563A1 (de) * 2019-01-17 2020-07-23 Lts Lohmann Therapie-Systeme Ag Applikator
CN109966636B (zh) * 2019-04-17 2025-01-24 苏州微亮生物科技有限公司 一种给药导入装置
CA3156411A1 (en) 2019-10-01 2021-04-08 Unomedical A/S An infusion set and a connector assembly for an infusion set that administer multiple fluids
KR20220110273A (ko) 2019-12-05 2022-08-05 소렌토 쎄라퓨틱스, 인코포레이티드 항-pd-1 또는 항-pd-l1 치료제를 림프 전달 장치를 통해 투여하여 암을 치료하는 방법
KR102548189B1 (ko) * 2020-10-20 2023-06-28 이오플로우(주) 약액 주입 장치
CN116348163A (zh) 2020-10-06 2023-06-27 欧弗洛有限公司 药液注射装置
CN117813128A (zh) 2021-01-22 2024-04-02 索伦托药业有限公司 用于微升级淋巴递送冠状病毒疫苗的装置
WO2022192594A2 (en) 2021-03-11 2022-09-15 Sorrento Therapeutics, Inc. Nucleic acid molecules and vaccines comprising same for the prevention and treatment of coronavirus infections and disease
US12178979B2 (en) 2021-10-13 2024-12-31 Satio, Inc. Dermal patch for delivering a pharmaceutical
US12048543B2 (en) 2021-11-08 2024-07-30 Satio, Inc. Dermal patch for collecting a physiological sample with removable vial
US12023156B2 (en) 2021-10-13 2024-07-02 Satio, Inc. Dermal patch for collecting a physiological sample
US11452474B1 (en) 2021-04-14 2022-09-27 Satio, Inc. Dual lever dermal patch system
US12053284B2 (en) 2021-11-08 2024-08-06 Satio, Inc. Dermal patch for collecting a physiological sample
US12214346B2 (en) 2021-10-13 2025-02-04 Satio, Inc. Dermal patch with a diagnostic test strip
US11877848B2 (en) 2021-11-08 2024-01-23 Satio, Inc. Dermal patch for collecting a physiological sample
US11964121B2 (en) 2021-10-13 2024-04-23 Satio, Inc. Mono dose dermal patch for pharmaceutical delivery
CA3221925A1 (en) 2021-06-09 2022-12-15 Sorrento Therapeutics, Inc. Method of treating cancer by administration of an anti-pd-1 or anti-pd-l1 therapeutic agent via a lymphatic microneedle delivery device
EP4373542B1 (en) 2021-07-23 2025-04-30 ConvaTec Limited Port with piercing means
US20250120905A1 (en) 2021-08-18 2025-04-17 Vivasor, Inc Therapeutic agents targeting the lymphatic system
CN116585606A (zh) * 2023-06-15 2023-08-15 徕兄健康科技(威海)有限责任公司 一种可自调节的局部麻醉用微针贴片
WO2025129128A1 (en) 2023-12-15 2025-06-19 Vivasor, Inc. Compositions and methods for non-viral delivery of therapeutic compounds
KR20250136558A (ko) * 2024-03-08 2025-09-16 주식회사 케어메디 약물 주입 장치의 주입관을 대상체에 삽입시키기 위한 어플리케이터 및 이를 포함하는 약물 주입 시스템

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5527288A (en) * 1990-12-13 1996-06-18 Elan Medical Technologies Limited Intradermal drug delivery device and method for intradermal delivery of drugs
CN1571685A (zh) * 2001-09-12 2005-01-26 贝克顿迪肯森公司 用于药物传送的微针为基础的笔装置和使用该装置的方法
CN101801452A (zh) * 2007-08-06 2010-08-11 宁静制药公司 用于去氨加压素药物给送的方法和设备
US7828771B2 (en) * 2007-07-26 2010-11-09 Entra Pharmaceuticals, Inc. Systems and methods for delivering drugs
US20110022002A1 (en) * 2008-12-16 2011-01-27 Medtronic Minimed, Inc. Needle insertion systems and methods
US20110288526A1 (en) * 2008-11-07 2011-11-24 Min Wei Pen Needle Assembly For Intradermal Injection
CN102725019A (zh) * 2010-01-08 2012-10-10 威斯康星校友研究基金会 用于基于微针的药物递送设备的囊状装置

Family Cites Families (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0429842B1 (en) 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Device for the transdermal administration of protein or peptide drug
TW279133B (enExample) 1990-12-13 1996-06-21 Elan Med Tech
US5279544A (en) 1990-12-13 1994-01-18 Sil Medics Ltd. Transdermal or interdermal drug delivery devices
IE72524B1 (en) 1994-11-04 1997-04-23 Elan Med Tech Analyte-controlled liquid delivery device and analyte monitor
US6186982B1 (en) 1998-05-05 2001-02-13 Elan Corporation, Plc Subcutaneous drug delivery device with improved filling system
WO1999029365A1 (en) * 1997-12-11 1999-06-17 Alza Corporation Device for enhancing transdermal agent flux
KR100576583B1 (ko) 1997-12-22 2006-05-04 알자 코포레이션 서방성 약물 송달 장치용 속도 조절막
US5957895A (en) 1998-02-20 1999-09-28 Becton Dickinson And Company Low-profile automatic injection device with self-emptying reservoir
US6251079B1 (en) * 1998-09-30 2001-06-26 C. R. Bard, Inc. Transthoracic drug delivery device
AUPP985099A0 (en) 1999-04-20 1999-05-13 Usf Filtration And Separations Group Inc. Membrane filtration manifold system
US6623457B1 (en) 1999-09-22 2003-09-23 Becton, Dickinson And Company Method and apparatus for the transdermal administration of a substance
WO2001041863A1 (en) * 1999-12-10 2001-06-14 Alza Corporation Device and method for enhancing microprotrusion skin piercing
AU3403201A (en) 2000-02-10 2001-08-20 Power Paper Ltd. Drug delivery device and method
AU2001247721A1 (en) * 2000-03-23 2001-10-03 Antares Pharma, Inc. Single use disposable jet injector
US6537242B1 (en) * 2000-06-06 2003-03-25 Becton, Dickinson And Company Method and apparatus for enhancing penetration of a member for the intradermal sampling or administration of a substance
US6656147B1 (en) 2000-07-17 2003-12-02 Becton, Dickinson And Company Method and delivery device for the transdermal administration of a substance
US6855131B2 (en) * 2000-10-13 2005-02-15 Alza Corporation Microprotrusion member retainer for impact applicator
EP1471953B1 (en) 2001-09-21 2011-02-16 Valeritas, Inc. Gas pressure actuated microneedle arrays, and systems and methods relating to same
US7429258B2 (en) * 2001-10-26 2008-09-30 Massachusetts Institute Of Technology Microneedle transport device
US7858112B2 (en) 2002-02-28 2010-12-28 Lintec Corporation Percutaneous absorption system and percutaneous absorption method
US7115108B2 (en) 2002-04-02 2006-10-03 Becton, Dickinson And Company Method and device for intradermally delivering a substance
US6780171B2 (en) * 2002-04-02 2004-08-24 Becton, Dickinson And Company Intradermal delivery device
US7047070B2 (en) 2002-04-02 2006-05-16 Becton, Dickinson And Company Valved intradermal delivery device and method of intradermally delivering a substance to a patient
MXPA05000597A (es) * 2002-07-19 2005-04-28 3M Innovative Properties Co Dispositivos de microaguja y aparatos de administracion por microaguja.
EP1590034B1 (en) 2002-10-07 2014-05-14 Biovalve Technologies, Inc. Microneedle array patch
EP1475113A1 (en) 2003-05-08 2004-11-10 Novo Nordisk A/S External needle inserter
CN2657686Y (zh) * 2003-09-25 2004-11-24 李玉红 输液器针头助扎定位支架
ATE446111T1 (de) 2003-10-21 2009-11-15 Novo Nordisk As Innerer flüssigkeitskonnektor zur herstellung einer flüssigkeitsverbindung
KR20060099520A (ko) 2003-10-21 2006-09-19 노보 노르디스크 에이/에스 의료용 피부 장착 장치
EP1682203B1 (en) 2003-10-23 2010-01-06 Novo Nordisk A/S Medical injection device mountable to the skin
EP1682217A4 (en) 2003-11-13 2008-04-30 Alza Corp SYSTEM UDN PROCEDURE FOR THE TRANSDERMAL LEVY
ZA200604661B (en) * 2003-12-18 2008-05-28 Novo Nordisk As Nozzle device with skin stretching means
US7611481B2 (en) 2004-03-24 2009-11-03 Corium International, Inc. Transdermal delivery device
WO2006015299A2 (en) 2004-07-30 2006-02-09 Microchips, Inc. Multi-reservoir device for transdermal drug delivery and sensing
EP1790375A4 (en) 2004-08-12 2009-06-17 Hisamitsu Pharmaceutical Co TRANSDERMAL MEDICINE ADMINISTRATION WITH MICRONADEL
US7699802B2 (en) 2005-05-03 2010-04-20 Pharmajet, Inc. Needle-less injector
US7842008B2 (en) * 2005-11-21 2010-11-30 Becton, Dickinson And Company Intradermal delivery device
US20100209483A1 (en) 2005-12-21 2010-08-19 Richard Franklin Transdermal delivery of meptazinol
TW200800223A (en) 2005-12-21 2008-01-01 Shire Pharmaceuticals Inc Transdermal delivery of meptazinol
JPWO2007091608A1 (ja) 2006-02-10 2009-07-02 久光製薬株式会社 マイクロニードル付き経皮薬物投与装置
JP2007289482A (ja) * 2006-04-26 2007-11-08 Transcutaneous Technologies Inc 経皮投与装置
KR100886633B1 (ko) 2006-07-14 2009-03-04 호남석유화학 주식회사 전면부에 피부를 통해 체내로 전달하고자 하는 물질의 수용공간을 갖는 피부 침투용 미세 돌기 장치
WO2008083209A2 (en) 2006-12-29 2008-07-10 Amir Genosar Hypodermic drug delivery reservoir and apparatus
AU2008209537B2 (en) 2007-01-22 2013-01-31 Corium Pharma Solutions, Inc. Applicators for microneedle arrays
US20100121307A1 (en) 2007-08-24 2010-05-13 Microfabrica Inc. Microneedles, Microneedle Arrays, Methods for Making, and Transdermal and/or Intradermal Applications
US7911480B2 (en) 2007-10-08 2011-03-22 Via Technologies, Inc. Compression of multiple-sample-anti-aliasing tile data in a graphics pipeline
CN201216811Y (zh) 2008-06-19 2009-04-08 陈青山 透皮给药微针阵列与软性成形面膜的集成结构
US20110097393A1 (en) 2008-06-25 2011-04-28 US WorldMeade, LLC Skin Patches and Sustained-Release Formulations Comprising Lofexidine for Transdermal and Oral Delivery
CN101745177A (zh) 2008-11-28 2010-06-23 上海百星药业有限公司 一次性使用并拥有自身动力的给药装置
RU85338U1 (ru) * 2009-02-24 2009-08-10 Государственное образовательное учреждение высшего профессионального образования "Курский государственный технический университет" Устройство для трансдермальной доставки лекарственных средств
KR101030752B1 (ko) * 2009-04-09 2011-04-26 한국생명공학연구원 유체전달을 조절할 수 있는 마이크로 니들 유닛
WO2010126174A1 (en) 2009-05-01 2010-11-04 Nanbu Plastics Co., Ltd. Transdermal administration device
US10010706B2 (en) * 2009-07-31 2018-07-03 3M Innovative Properties Company Hollow microneedle arrays
BR112012003243B1 (pt) * 2009-08-11 2021-09-21 Neodyne Biosciences, Inc Sistemas para o tratamento de um paciente
WO2011075101A1 (en) * 2009-12-16 2011-06-23 Becton, Dickinson And Company Self-injection device
US20110172645A1 (en) 2010-01-08 2011-07-14 Ratio, Inc. Wearable drug delivery device including integrated pumping and activation elements
US20110172638A1 (en) 2010-01-08 2011-07-14 Ratio, Inc. Drug delivery device including multi-functional cover
US20110172609A1 (en) 2010-01-08 2011-07-14 Ratio, Inc. Microneedle component assembly for drug delivery device
US20110172637A1 (en) 2010-01-08 2011-07-14 Ratio, Inc. Drug delivery device including tissue support structure
JP5735773B2 (ja) * 2010-03-29 2015-06-17 シスメックス株式会社 生体成分分析方法及び生体成分分析装置
US9687641B2 (en) 2010-05-04 2017-06-27 Corium International, Inc. Method and device for transdermal delivery of parathyroid hormone using a microprojection array
AU2011248166B2 (en) 2010-05-04 2015-12-17 Corium Pharma Solutions, Inc. Applicators for microneedles
US8668675B2 (en) 2010-11-03 2014-03-11 Flugen, Inc. Wearable drug delivery device having spring drive and sliding actuation mechanism
US9017289B2 (en) 2010-11-03 2015-04-28 Covidien Lp Transdermal fluid delivery device
CN102671291B (zh) * 2011-03-14 2014-07-30 中国人民解放军军事医学科学院毒物药物研究所 基于渗透压为动力的可控微输注装置
CN202173684U (zh) * 2011-08-26 2012-03-28 吴翠岗 一种微针美容仪
CN202590041U (zh) * 2012-05-21 2012-12-12 王金峰 注射局部皮肤拉紧器
CN202740542U (zh) * 2012-08-06 2013-02-20 安徽理工大学 无针注射器的辅助注射装置

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5527288A (en) * 1990-12-13 1996-06-18 Elan Medical Technologies Limited Intradermal drug delivery device and method for intradermal delivery of drugs
CN1571685A (zh) * 2001-09-12 2005-01-26 贝克顿迪肯森公司 用于药物传送的微针为基础的笔装置和使用该装置的方法
US7828771B2 (en) * 2007-07-26 2010-11-09 Entra Pharmaceuticals, Inc. Systems and methods for delivering drugs
CN101801452A (zh) * 2007-08-06 2010-08-11 宁静制药公司 用于去氨加压素药物给送的方法和设备
US20110288526A1 (en) * 2008-11-07 2011-11-24 Min Wei Pen Needle Assembly For Intradermal Injection
US20110022002A1 (en) * 2008-12-16 2011-01-27 Medtronic Minimed, Inc. Needle insertion systems and methods
CN102725019A (zh) * 2010-01-08 2012-10-10 威斯康星校友研究基金会 用于基于微针的药物递送设备的囊状装置

Also Published As

Publication number Publication date
JP2016511679A (ja) 2016-04-21
KR102295456B1 (ko) 2021-08-27
CA2901568C (en) 2021-02-16
BR112015020328A2 (pt) 2017-07-18
KR20150126617A (ko) 2015-11-12
RU2622605C2 (ru) 2017-06-16
CN109621083B (zh) 2022-03-22
EP2961471A1 (en) 2016-01-06
KR102370538B1 (ko) 2022-03-07
MX360121B (es) 2018-10-03
JP6839223B2 (ja) 2021-03-03
CN105073179A (zh) 2015-11-18
KR20220034913A (ko) 2022-03-18
US20210170153A1 (en) 2021-06-10
AU2014222308B2 (en) 2018-11-08
JP2019162444A (ja) 2019-09-26
EP2961471B1 (en) 2023-10-25
US20150367117A1 (en) 2015-12-24
US10183156B2 (en) 2019-01-22
RU2015138281A (ru) 2017-03-20
AU2014222308A1 (en) 2015-09-24
US11883622B2 (en) 2024-01-30
MX2015011071A (es) 2015-10-29
CA2901568A1 (en) 2014-09-04
WO2014132240A1 (en) 2014-09-04
JP6522523B2 (ja) 2019-05-29
US10953211B2 (en) 2021-03-23
CN109621083A (zh) 2019-04-16
EP2961471A4 (en) 2017-04-05
BR112015020328B1 (pt) 2022-05-31
KR20210107180A (ko) 2021-08-31
KR102571835B1 (ko) 2023-08-30
US20190134369A1 (en) 2019-05-09

Similar Documents

Publication Publication Date Title
CN105073179B (zh) 经皮药物递送装置
JP2022103381A (ja) 経皮的薬物送達装置および方法
US7115108B2 (en) Method and device for intradermally delivering a substance
KR101497164B1 (ko) 마이크로 미세바늘 경피 전달 장치
KR20220110542A (ko) 마이크로니들을 갖는 유체 전달 기구
CN106535979A (zh) 透皮药物递送设备的控制器部分和方法
EP2961469A1 (en) Drug delivery device

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
TA01 Transfer of patent application right

Effective date of registration: 20190125

Address after: American California

Applicant after: Sorrento Therapeutics Inc.

Address before: Wisconsin

Applicant before: Kimberly-Clark Worldwide, Inc.

TA01 Transfer of patent application right
GR01 Patent grant
GR01 Patent grant