CN105056108A - Traditional Chinese medicine for treating upper limb lymphedema after breast cancer operation - Google Patents
Traditional Chinese medicine for treating upper limb lymphedema after breast cancer operation Download PDFInfo
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- CN105056108A CN105056108A CN201510450285.3A CN201510450285A CN105056108A CN 105056108 A CN105056108 A CN 105056108A CN 201510450285 A CN201510450285 A CN 201510450285A CN 105056108 A CN105056108 A CN 105056108A
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Abstract
The invention relates to a traditional Chinese medicine for treating upper limb lymphedema after a breast cancer operation. The traditional Chinese medicine is prepared from the following raw herbal materials in weight proportion: 15 parts of earthworm, 30 parts of rhizoma curcumae, 30 parts of coix seed, 15 parts of fructus liquidambaris, 15 parts of old bottle gourd peel, 15 parts of loofah sponge, 15 parts of whole herb of salomonia cantoniensis, 15 parts of hiraute shiny bugleweed herb, and 30 parts of leaf of Japanese glorybower. Clinical experiment results show that by adopting the traditional Chinese medicine provided by the invention, the upper limb lymphedema after the breast cancer operation can be safely and effectively treated.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine being used for the treatment of Mammary cancer upper limb lymphedema.
Background technology
Lymphedema refers to soft tissue liquid subcutaneous fibrotic connective tissue proliferation after body surface repeated infection that some position lymph fluid backflow obstruction of body causes, adiposclerosis, if limbs then increase slightly, later stage pachyderma, coarse, tough and tensile as Corium elephatis, also known as " elephatiasis ".It is the postoperative more common complication of mammary cancer radical operation, the Crack cause of Mammary cancer upper limb lymphedema is a lot, relevant with following factors: axillary lymph node dissection mode is improper, remove that scope is excessive, tunica adventitia damage, post-operative infection, postoperative too early, excessive radiotherapy and advanced age, obesity etc.
Mammary cancer upper limb lymphedema belongs to the traditional Chinese medical science " edema ", " BI-syndrome involved the blood vessels " category.The traditional Chinese medical science is thought and is killd blood trouble vitality of pulse warp by golden sword in patient with breast cancer's art, in addition postoperative Radiotherapy chemotherapy consumption impairment of QI blood, make weakened body resistance person more empty, domination of pathogen person is more real, the unable promotion blood of the deficiency of vital energy, hematogenous blockage, venation block increases the weight of, menstruation disorder is then water, and the deficiency of vital energy cause water liquid can not compress and stagnating, the unboiled water in skin that overflows swells." so-called blood stasis person, namely changes and is unphysiologic blood, then not only the use of liquid of having lost blood, and be the poison of human body, namely must discharge in external, though a moment can not take it in ".Therefore, blood circulation promoting and blood stasis dispelling is effective rule for the treatment of of control Mammary cancer lymphedema complication.
Medical material present Research involved in the present invention is as follows:
Pheretima [another name] Lumbricus, cricket earthworm, bent worm, native Dan, red worm.[source] this product is the dry body of Ju Yin section animal Pheretima aspergillum, popular Pheretimatschiliensis, power simulation or the blind Pheretimatschiliensis of comb.Front one is practised and is claimed " LUMBRICUS ", practises title " Shanghai Pheretima " for latter three kinds.LUMBRICUS catches to autumn spring, and Shanghai Pheretima catches summer, cuts abdominal part open in time, and removing internal organs and silt are cleaned, dried or cold drying.[nature and flavor] are salty, cold.[return through] returns liver, spleen, urinary bladder channel.[function cures mainly] heat clearing away is calmed the frightened, and dredging collateral, relievings asthma, diuresis.For unconsciousness due to high fever, infantile convulsion is twitched, arthralgia, numb limbs and tense tendons, hemiplegia, dyspnea and cough due to lung-heat, oliguria edema, hypertension.[usage and dosage] takes orally: decoct soup, 4.5-9g.[attention] Deficiency and coldness of spleen and stomach should not take, and anemia of pregnant woman prohibits clothes.[extracts] " China's book on Chinese herbal medicine ".
Rhizoma Curcumae [another name] Curcuma wenyujin, Rhizoma Curcumae, radix zedoariae, Rhizoma Trillii Tschonoskii, smelly dung Rhizoma Zingiberis Recens.[source] this product is the dry rhizome of zingiberaceous plant Rhizoma Curcumae, Guangxi zedoary or RADIX CURCUMAE.The latter practises title " Curcuma wenyujin ".Winter, stem and leaf was excavated after withering, and cleaned, steamed or boil to the saturating heart, dry or remove fibrous root and impurity after cold drying.[nature and flavor] are pungent, bitter, temperature.[return through] returns liver, spleen channel.[function cures mainly] circulation of qi promoting removing blood stasis, removing food stagnancy pain relieving.For Dan abdominal mass mass in the abdomen, blood stasis amenorrhea, food stagnation distending pain; Early cervical carcinoma.[usage and dosage] takes orally: decoct soup, 6 ~ 12g.[attention] anemia of pregnant woman is forbidden.QI and blood deficiency, weakness of spleen and stomach is without the careful clothes of stagnant person.[extracts] " China's book on Chinese herbal medicine ".
Semen Coicis [another name] Semen Coicis, Semen Coicis, seed of Job's tears, ditch rice.[source] this product is the dry mature kernal of grass Semen Coicis.Tap plant during fruit maturation in autumn, dry, lay fruit, then dry, except decapsidate, yellowish-brown seed coat and impurity, collect kernel.[nature and flavor] are sweet, light, cool.[return through] returns spleen, stomach, lung meridian.[function cures mainly] spleen invigorating eliminating dampness by diuresis, eliminating impediment antidiarrheal, row is dense in heat clearing away.For edema, beriberi, dysuria, arthralgia chiefly caused by damp pathogen contracture, diarrhea due to hypofunction of the spleen, lung abscess, intestinal carbuncle; Verruca plana .[usage and dosage] for oral administration: decoct soup, 9 ~ 30g.[attention] spleen-constipation dyschezia and the careful clothes of pregnant woman.[extracts] " China's book on Chinese herbal medicine ".
Ball, sweetgum fruit, maple fruit, Nie Zi, wolf order, maple ball, wolves' eyes, maple ball, nine gaps in Fructus Liquidambaris [another name] maple reality, maple.[source] this product is the drying and ripening infructescence of Hamamelidaceae Plants Chinese sweet gum.Winter gathers after fruit maturation, removing impurity, dry.[nature and flavor] are bitter, flat.[return through] returns liver, kidney channel.[function cures mainly] dispelling, collateral-activating, diuretic stimulates the menstrual flow.For arthralgia, numbness contracture, edema distension, the few amenorrhea of breast.[usage and dosage] takes orally: decoct soup, 5 ~ 9g.[attention] all menorrhagia and contraindication in pregnancy.[extracts] " China's book on Chinese herbal medicine ".
Pericarpium Lagenariae (pericarpium Lagenariae sicerariae) [another name] old Pericarpium Lagenariae sicerariae wooden dipper, broken wooden dipper, lose wooden dipper, lose an a kind of edible gourd, calabash shell, Pericarpium Lagenariae sicerariae, old a kind of edible gourd shell.The aging fruit shell that [source] is cucurbitaceous plant calabash calabash courd and small gourd.Gather and store: calabash and calabash courd: the time of the year when autumn changes into winter takes aging fruit, cutting, removing flesh heart seed, smashes, dries.Small gourd: autumn clothes take shell to be yellow aging fruit, dry after scraping off outer thin skin with ceramics.[nature and flavor] sweet in the mouth; Bitter; Property is put down.[return through] returns Liver Channel.[function cures mainly] diuretic; Detumescence.Main edema; Expand.[usage and dosage] takes orally: decoct soup, 10 ~ 30g.[extracts] " China's book on Chinese herbal medicine ".
Retinervus Luffae Fructus [another name] Fructus Luffae net, Fructus Luffae shell, melon network, wadding melon pulp, sky sieve line, vegetable sponge, chalina, Hypericum perforatum L..[source] this product is the vascular bundle of the dry mature fruit of cucurbitaceous plant Fructus Luffae.Summer, season in autumn two fruit maturation, peel turns yellow, inner withered time pluck, removing crust and sarcocarp, clean, dry, removing seed.[nature and flavor] are sweet, flat.[return through] returns lung, stomach, Liver Channel.[function cures mainly] dredging collateral, invigorates blood circulation, dispels the wind.For arthralgia pain contracture, distending pain in the chest and hypochondrium, galactostasis.[usage and dosage] takes orally: decoct soup, 4.5 ~ 9g.[extracts] " China's book on Chinese herbal medicine ".
Herba Salomoniae Cantoniensis [another name] blows soul grass, Gong Ercao, one bowl of bubble, river wind, the Serpentis that passes by one's way, little greasy medicine, thin xanthate.[source] is the herb of milk wort tooth fruit grass, gathers and stores: herb of gathering in summer, autumn, cleans, using fresh herb or dry.[nature and flavor] taste is micro-pungent; Property is put down.[return through] enters the heart; Liver Channel.[function cures mainly] removing toxic substances and promoting subsidence of swelling; Eliminating stasis to stop pain.Main carbuncle skin infection; Innominate toxic swelling; Sore throat; Venom; Traumatic injury; Rheumatic arthritis; Toothache.[usage and dosage] takes orally: decoct soup, 3 ~ 10g.[attention] carbuncle has been burst and should not have been taken, and variola insufficiency of primordial QI can not play originator, should not take.[extracts] " China's book on Chinese herbal medicine ".
Herba Lycopi's [another name] lycopus lucidus, Rhizoma Lycopi Lucidi, Chinese artichoke, stalk Herba Lycopi .[source, side] this product is the dry aerial parts of labiate hair leaf lycopus lucidus.Tap when summer, autumn, stem and leaf was luxuriant, dry.[nature and flavor] are bitter, pungent, tepor.[return through] returns liver, spleen channel.[function cures mainly] blood circulation promoting and blood stasis dispelling, line water detumescence.For menoxenia, amenorrhea, dysmenorrhea, postnatal blood stasis is suffered from abdominal pain, edema.[usage and dosage] takes orally: decoct soup, 6 ~ 12g.[attention] is without the careful clothes of blood stasis person.[extracts] " China's book on Chinese herbal medicine ".
The red Aeschna melanictera leaf of Folium Clerodendri japonici [another name].[source] is the leaf of dicotyledon medicine Verenaceae Zhi Wu Cheng paulownia.Gather and store: the whole year all can adopt, and dries, grinding into powder or using fresh herb.[nature and flavor] are pungent; Sweet; Flat.[return through] returns liver; Spleen channel.[function cures mainly] dispels the wind; Dissipating blood stasis; Removing toxic substances and promoting subsidence of swelling.Main migraine; Traumatic injury congestive edema; Carbuncle sore tumefacting virus.[usage and dosage] takes orally: decoct soup, 9 ~ 30g.[extracts] " China's book on Chinese herbal medicine ".
Summary of the invention
The present invention aims to provide a kind of Chinese medicine being used for the treatment of Mammary cancer upper limb lymphedema, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing Mammary cancer upper limb lymphedema.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine being used for the treatment of Mammary cancer upper limb lymphedema, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Pheretima 15 parts, Rhizoma Curcumae 30 parts, Semen Coicis 30 parts, Fructus Liquidambaris 15 parts, Pericarpium Lagenariae (pericarpium Lagenariae sicerariae) 15 parts, Retinervus Luffae Fructus 15 parts, Herba Salomoniae Cantoniensis 15 parts, Herba Lycopi 15 Fen, Folium Clerodendri japonici 30 parts.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Outpatient service is collected and Mammary cancer upper limb lymphedema patient 101 example of being in hospital altogether in inventor in October, 2012 ~ 2013 between year October, be divided into treatment group 52 example and matched group 49 example at random, 21 ~ 68 years old treatment group age, 43 years old mean age; 20 ~ 65 years old matched group age, 41 years old mean age.2 groups of ages and course of disease comparing difference not statistically significant, have comparability.
Diagnostic criteria
Diagnostic criteria according to the meeting of national Mammary cancer upper limb lymphedema clinical speciality: on 10cm place, ancon and elbow, 10cm place measures its week footpath and strong side respectively and contrasts on suffering limb rasceta place, wrist.1. Mild edema: Zhou Jing below the 3cm thicker than strong side of ipsilateral upper limb, is limited to upper arm near-end more, often betides Post operation in a short time.2. intermediate edema: the Zhou Jing 3 ~ 6cm thicker than strong side of ipsilateral upper limb, the range effects of edema, to whole upper limb, comprises forearm and the back of the hand.3. severe edema: Zhou Jing more than the 6cm thicker than strong side of ipsilateral upper limb, skin is firmly tough, and edema involves whole upper limb and comprises finger, makes the whole upper arm of patient and shoulder mobility critical constraints.
2, test method
2.1 Therapeutic Method
The capsule that the oral the present invention for the treatment of group obtains according to specific embodiment 3, every day 3 times.Within 10th, be 1 course for the treatment of, treat 2 courses for the treatment of altogether.
The oral hydrochlorothiazide 50mg of matched group, every day 3 times is oral; Spironolactone 20mg, every day 3 times is oral.Within 10th, be 1 course for the treatment of, treat 2 courses for the treatment of altogether.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Clinic control: compare before and after treatment, after treatment, suffering limb Zhou Jing is close with strong limb.Edema extinction reaches or close to 100%;
Effective: Zhou Jing reduces, edema extinction > 50%;
Effective: Zhou Jing reduces, edema extinction < 50%;
Invalid: before and after treatment, edema is not improved.
3.2 therapeutic outcomes are in table 1.
Table 1 liang group comparitive study
Visible, the medicine that the present invention obtains can safe and effective treatment Mammary cancer upper limb lymphedema, has promotional value.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Embodiment 1
Take: Pheretima 15 grams, Rhizoma Curcumae 30 grams, Semen Coicis 30 grams, Fructus Liquidambaris 15 grams, Pericarpium Lagenariae (pericarpium Lagenariae sicerariae) 15 grams, Retinervus Luffae Fructus 15 grams, Herba Salomoniae Cantoniensis 15 grams, Herba Lycopi 15 Ke, Folium Clerodendri japonici 30 grams; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.
Be used for the treatment of Mammary cancer upper limb lymphedema.Oral, every bu Morning Afternoon Evening is taken for three times.
Embodiment 2
Take: Pheretima 15 grams, Rhizoma Curcumae 30 grams, Semen Coicis 30 grams, Fructus Liquidambaris 15 grams, Pericarpium Lagenariae (pericarpium Lagenariae sicerariae) 15 grams, Retinervus Luffae Fructus 15 grams, Herba Salomoniae Cantoniensis 15 grams, Herba Lycopi 15 Ke, Folium Clerodendri japonici 30 grams; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.
Be used for the treatment of Mammary cancer upper limb lymphedema.Oral, every bu Morning Afternoon Evening is taken for three times.
Embodiment 3
Take: Pheretima 15 grams, Rhizoma Curcumae 30 grams, Semen Coicis 30 grams, Fructus Liquidambaris 15 grams, Pericarpium Lagenariae (pericarpium Lagenariae sicerariae) 15 grams, Retinervus Luffae Fructus 15 grams, Herba Salomoniae Cantoniensis 15 grams, Herba Lycopi 15 Ke, Folium Clerodendri japonici 30 grams; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.
Be used for the treatment of Mammary cancer upper limb lymphedema.Oral, every bu Morning Afternoon Evening is taken for three times.
Claims (1)
1. one kind is used for the treatment of the Chinese medicine of Mammary cancer upper limb lymphedema, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Pheretima 15 parts, Rhizoma Curcumae 30 parts, Semen Coicis 30 parts, Fructus Liquidambaris 15 parts, Pericarpium Lagenariae (pericarpium Lagenariae sicerariae) 15 parts, Retinervus Luffae Fructus 15 parts, Herba Salomoniae Cantoniensis 15 parts, Herba Lycopi 15 Fen, Folium Clerodendri japonici 30 parts.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105232985A (en) * | 2015-10-29 | 2016-01-13 | 陈刚 | Traditional Chinese medicine for treating epileptiform neuralgia |
| CN107115416A (en) * | 2016-02-24 | 2017-09-01 | 天津禾盛医药技术开发有限公司 | Treat the traditional Chinese medicinal ointment and preparation method of Mammary cancer ipsilateral upper limb swelling |
| CN107320687A (en) * | 2017-07-15 | 2017-11-07 | 管志斌 | A kind of Chinese medicine preparation and preparation method for treating tumefaction of membrum superius after mammary cancer operation |
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| JP2013213015A (en) * | 2012-04-04 | 2013-10-17 | Morishita Jintan Co Ltd | Tie2 activating agent |
| CN103961659A (en) * | 2014-06-03 | 2014-08-06 | 丛宁 | Traditional Chinese medicine for treating lymphedema of upper limbs after breast cancer operation and preparation method thereof |
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2015
- 2015-07-28 CN CN201510450285.3A patent/CN105056108A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013213015A (en) * | 2012-04-04 | 2013-10-17 | Morishita Jintan Co Ltd | Tie2 activating agent |
| CN103961659A (en) * | 2014-06-03 | 2014-08-06 | 丛宁 | Traditional Chinese medicine for treating lymphedema of upper limbs after breast cancer operation and preparation method thereof |
Non-Patent Citations (1)
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| 刘真: "《别让乳腺癌盯上你》", 31 March 2015, 中国医药科技出版社 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105232985A (en) * | 2015-10-29 | 2016-01-13 | 陈刚 | Traditional Chinese medicine for treating epileptiform neuralgia |
| CN107115416A (en) * | 2016-02-24 | 2017-09-01 | 天津禾盛医药技术开发有限公司 | Treat the traditional Chinese medicinal ointment and preparation method of Mammary cancer ipsilateral upper limb swelling |
| CN107320687A (en) * | 2017-07-15 | 2017-11-07 | 管志斌 | A kind of Chinese medicine preparation and preparation method for treating tumefaction of membrum superius after mammary cancer operation |
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