CN105056010A - Agentia for treating arrhythmia and making method - Google Patents
Agentia for treating arrhythmia and making method Download PDFInfo
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Abstract
The invention discloses agentia for treating arrhythmia. The agentia is composed of, by weight, 12-18 parts of angelica sinensis, 10-16 parts of rhodobryum roseum, 8-13 parts of cynanchum amplexicaule, 6-12 parts of sinuate tickclover herbs, 9-13 parts of acorus gramineus, 8-12 parts of crocus sativus, 10-13 parts of roots of clerodendron cyrtophyllum turcz, 11-15 parts of choerospondias axillaries, 9-14 parts of epiphyllum, 7-12 parts of callicarpa longissima, 10-14 parts of cassia twigs, 9-15 parts of malt, 7-13 parts of bauhinia championii, 10-16 parts of ophiopogon roots and 8-14 parts of perny false fairybells rhizome. The agentia is effective in treatment, low in untoward effect and high in safety. The agentia is developed by combining the traditional Chinese medicine principle with the clinical experiences in many years. The agentia has the effects of tonifying qi and yin, calming the heart, promoting circulation of qi and the like. The agentia is wide in medicine source, low in cost and free of economical burden after being taken for a long time.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to the ARR medicament of a kind for the treatment of and method for making.
Background technology
Arrhythmia is because the exciting exception of sinuatrial node or excitement result from beyond sinuatrial node; exciting conduction slowly, retardance or through abnormal passage conduction, namely the origin of cardiomotility and (or) conductive impairment cause frequency and (or) the allorhythmia of heartbeat.Arrhythmia is one group of disease important in cardiovascular disease.It can be fallen ill separately and also can occur together with cardiovascular diseases.Can break out and cause sudden death, also sustainablely involving heart and exhaustion.Slight arrhythmia is without obvious clinical manifestation, and heavier arrhythmia can cause cardiopalmus, uncomfortable in chest, dizzy, hypotension, perspiration, and fainting appears in severe patient, Adams Stokes syndrome, even dies suddenly.Clinical manifestation is different because types of arrhythmia is different.Drug therapy is ARR primary treatments.By the application of general medicine based on oral.The rule of clinical application is that selection is with strong points according to ARR mechanism, and curative effect is the little medicine of untoward reaction obviously.
Publication No. CN104173916A(application number 201410361176.X) Chinese patent literature disclose one and treat ARR Chinese medicine preparation, raw medicinal material is Radix Angelicae Sinensis 10 parts, Radix Paeoniae Rubra 10 parts, 9 parts, Flos Carthami, succinum 8 parts, RADIX CURCUMAE 9 parts, Rhizoma Chuanxiong 9 parts, SHIXIAO SAN 8 parts, Radix Bupleuri 10 parts, Fructus Aurantii 12 parts respectively.Publication No. CN104645014A(application number 201310600804.0) Chinese patent literature disclose one and treat ARR Chinese medicine formula, constituent is: Radix Salviae Miltiorrhizae, Caulis Spatholobi, Radix Codonopsis are each, Rhizoma Corydalis, Flos Carthami, Radix Ophiopogonis, Fructus Schisandrae Chinensis, Poria, Radix Glycyrrhizae.Publication No. CN104758553A(application number 201510182945.4) Chinese patent literature disclose one and be used for the treatment of ARR Chinese medicine, medical material comprises: Bulbus Allii Macrostemonis 10 parts, Radix Ginseng 10 parts, Fructus Schisandrae Chinensis 15 parts, 25 parts, the Radix Rehmanniae, Radix Angelicae Sinensis 10 parts, Ramulus Cinnamomi 10 parts, Poria cum Radix Pini 12 parts, Bai Ren 15 parts, Radix Polygalae 10 parts.
Western medicine arrhythmia does not destroy arrhythogenic pathological tissue; diseased region myocardium cellular electrophysiologicalsensor performance such as conduction velocity and (or) refractory stage length is only made to change to some extent; long-term taking all has adverse side effect in various degree; serious caused ventricular arrhythmia or heart block and fatal; comparatively speaking; Chinese traditional treatment safety and stability; side effect is less; traditional Chinese medical science formula at present about this disease for the treatment of also has many; but curative effect difference is larger; thus, needs are had to work out the reliable traditional Chinese medical science formula of a kind of determined curative effect.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide that a kind of curative effect is reliable, the ARR medicament for the treatment of of effect stability and method for making.
Technical scheme of the present invention is:
The ARR medicament of a kind for the treatment of, is prepared from primarily of following bulk drugs, is mass parts: Radix Angelicae Sinensis 12-18, Rhodobryum roseum Limpr. 10-16, Radix Cynanchi Amplexicaulis 8-13, Herba Desmodii sequacis 6-12, Rhizoma Acori Graminei 9-13, Stigma Croci 8-12, Radix Clerodenri Cyrtophylli 10-13, Fructus Choerospondiatis 11-15, Flos Epiphylli Oxypetali 9-14, Caulis te Folium Callicarpae Longissimae 7-12, Ramulus Cinnamomi 10-14, Fructus Hordei Germinatus 9-15, Caulis Bauhihiae Championii 7-13, Radix Ophiopogonis 10-16, Rhizoma disporopsis pernyi 8-14.
In preferred scheme, Radix Angelicae Sinensis 14-16, Rhodobryum roseum Limpr. 12-14, Radix Cynanchi Amplexicaulis 9-12, Herba Desmodii sequacis 8-10, Rhizoma Acori Graminei 10-12, Stigma Croci 9-11, Radix Clerodenri Cyrtophylli 11-12, Fructus Choerospondiatis 12-14, Flos Epiphylli Oxypetali 10-13, Caulis te Folium Callicarpae Longissimae 8-11, Ramulus Cinnamomi 11-13, Fructus Hordei Germinatus 10-14, Caulis Bauhihiae Championii 9-11, Radix Ophiopogonis 12-14, Rhizoma disporopsis pernyi 10-12.
Be more preferably, Radix Angelicae Sinensis 15, Rhodobryum roseum Limpr. 13, Radix Cynanchi Amplexicaulis 10.5, Herba Desmodii sequacis 9, Rhizoma Acori Graminei 11, Stigma Croci 10, Radix Clerodenri Cyrtophylli 11.5, Fructus Choerospondiatis 13, Flos Epiphylli Oxypetali 11.5, Caulis te Folium Callicarpae Longissimae 9.5, Ramulus Cinnamomi 12, Fructus Hordei Germinatus 12, Caulis Bauhihiae Championii 10, Radix Ophiopogonis 13, Rhizoma disporopsis pernyi 11.
Described one cures ARR medicament, and be made into pharmaceutically acceptable capsule, its preparation method is:
(1) get Rhodobryum roseum Limpr. sucrose solution on the rocks to boil, the amount of crystal sugar water is 2 times of Rhodobryum roseum Limpr. quality, boils when exhausting to water, takes out, dries, dry in the air cool;
(2) by Fructus Hordei Germinatus and Radix Ophiopogonis, clean, be placed in frying pan, add propagandize hotly to crude drug surface yellowish-brown time, mix thoroughly with Sucus Zingberis, treat juice exhaust take out, dry;
(3) get Stigma Croci and add yellow wine and refined honey is mixed thoroughly, moistening, load and steam in cup, Steam by water bath exhausts to soup, Guan Huo, cools, and takes out, dries, pulverize together with step (1) (2) made crude drug;
(4) Radix Angelicae Sinensis, Radix Cynanchi Amplexicaulis, Herba Desmodii sequacis, Rhizoma Acori Graminei, Radix Clerodenri Cyrtophylli, Fructus Choerospondiatis, Flos Epiphylli Oxypetali, Caulis te Folium Callicarpae Longissimae, Ramulus Cinnamomi, Caulis Bauhihiae Championii and Rhizoma disporopsis pernyi roguing are cleaned, decoct with water three times, first time big fire boils 30 minutes, second time big fire boils 25 minutes, third time big fire boils 20 minutes, filter, collect filtrate, merge three gained filtrates;
(5) join in step (4) made filtrate by step (3) made medicated powder, concentrated, dry, pulverize, incapsulate, every capsules loads medicated powder 0.35g, obtains capsule.
Described a kind of preparation method curing ARR drug capsule agent, step (4) decocts with water the 6-8 that institute's amount of water is boiled crude drug quality at every turn, and doubly (preferred, the 6.5-7.5 that institute's amount of water is boiled crude drug quality is doubly; Be more preferably, institute's amount of water is 7 times of boiled crude drug quality).
Described one cures ARR medicament, and be made into pharmaceutically acceptable powder, its preparation method is:
(1) get Rhodobryum roseum Limpr. sucrose solution on the rocks to boil, the amount of crystal sugar water is 2 times of Rhodobryum roseum Limpr. quality, boils when exhausting to water, takes out, dries, dry in the air cool;
(2) by Fructus Hordei Germinatus and Radix Ophiopogonis, clean, be placed in frying pan, add propagandize hotly to crude drug surface yellowish-brown time, mix thoroughly with Sucus Zingberis, treat juice exhaust take out, dry;
(3) get Stigma Croci and add yellow wine and refined honey is mixed thoroughly, moistening, load and steam in cup, Steam by water bath exhausts to soup, Guan Huo, cools, and takes out, dries, pulverize together with step (1) (2) made crude drug;
(4) Radix Angelicae Sinensis, Radix Cynanchi Amplexicaulis, Herba Desmodii sequacis, Rhizoma Acori Graminei, Radix Clerodenri Cyrtophylli, Fructus Choerospondiatis, Flos Epiphylli Oxypetali, Caulis te Folium Callicarpae Longissimae, Ramulus Cinnamomi, Caulis Bauhihiae Championii and Rhizoma disporopsis pernyi roguing are cleaned, decoct with water three times, decoct with water 7 times that institute's amount of water is boiled crude drug quality at every turn, first time big fire boils 30 minutes, second time big fire boils 25 minutes, and third time big fire boils 20 minutes, filters, collect filtrate, merge three gained filtrates;
(5) by step (4) made filtrate, concentrated, dry, pulverize, medicated powder stirring and evenly mixing made with step (3), obtains powder.
Described a kind of preparation method curing ARR medicament powder, step (3) was pulverized 100-180 mesh sieve and (preferably, was pulverized 120-160 mesh sieve; Be more preferably, pulverized 140 mesh sieves).
Described one cures ARR medicament, and be made into pharmaceutically acceptable decoction, its preparation method is:
(1) get Rhodobryum roseum Limpr. sucrose solution on the rocks to boil, the amount of crystal sugar water is 5 times of Rhodobryum roseum Limpr. quality, boils when reducing by half to water, filters, and collects filtrate;
(2) by Fructus Hordei Germinatus and Radix Ophiopogonis, clean, be placed in frying pan, add propagandize hotly to crude drug surface yellowish-brown time, mix thoroughly with Sucus Zingberis, treat juice exhaust take out, dry;
(3) get Stigma Croci and add yellow wine and refined honey is mixed thoroughly, moistening, load and steam in cup, Steam by water bath exhausts to soup, Guan Huo, cools, and takes out, dries, and pulverizes, makes medicated powder;
(4) Radix Angelicae Sinensis, Radix Cynanchi Amplexicaulis, Herba Desmodii sequacis, Rhizoma Acori Graminei, Radix Clerodenri Cyrtophylli, Fructus Choerospondiatis, Flos Epiphylli Oxypetali, Caulis te Folium Callicarpae Longissimae, Ramulus Cinnamomi, Caulis Bauhihiae Championii and Rhizoma disporopsis pernyi roguing are cleaned, decoct with water together with step (2) made crude drug, first time big fire is boiled rear little fire and is decocted 30-38 minute (preferably, little fire decocts 34 minutes), second time big fire is boiled rear little fire and is decocted, and decocts 7 times that amount of water is boiled crude drug quality for twice, filters, collect, and merge twice gained filtrate;
(5) step (1) and step (4) made filtrate are merged, add step (3) made medicated powder, mixing, obtains decoction.
Described a kind of preparation method curing ARR medicament decoction, the big fire of step (4) second time is boiled rear little fire and is decocted 22-30 minute (preferred, little fire decocts 26 minutes).
Described one cures ARR medicament, and be made into pharmaceutically acceptable pill, its preparation method is:
(1) get Rhodobryum roseum Limpr. sucrose solution on the rocks to boil, the amount of crystal sugar water is 2 times of Rhodobryum roseum Limpr. quality, boils when exhausting to water, takes out, dries, dry in the air cool;
(2) by Fructus Hordei Germinatus and Radix Ophiopogonis, clean, be placed in frying pan, add propagandize hotly to crude drug surface yellowish-brown time, mix thoroughly with Sucus Zingberis, treat juice exhaust take out, dry;
(3) get Stigma Croci and add yellow wine and refined honey is mixed thoroughly, moistening, load and steam in cup, Steam by water bath exhausts to soup, Guan Huo, cools, and takes out, dries, pulverize together with step (1) (2) made crude drug;
(4) Radix Angelicae Sinensis, Radix Cynanchi Amplexicaulis, Herba Desmodii sequacis, Rhizoma Acori Graminei, Radix Clerodenri Cyrtophylli, Fructus Choerospondiatis, Flos Epiphylli Oxypetali, Caulis te Folium Callicarpae Longissimae, Ramulus Cinnamomi, Caulis Bauhihiae Championii and Rhizoma disporopsis pernyi roguing are cleaned, decoct with water three times, decoct with water 7 times that institute's amount of water is boiled crude drug quality at every turn, first time big fire boils 30 minutes, second time big fire boils 25 minutes, and third time big fire boils 20 minutes, filters, collect filtrate, merge three gained filtrates;
(5) by step (4) made filtrate, concentrated, dry, pulverize, medicated powder stirring and evenly mixing made with step (3), add water and generally make ball, obtain pill.
Described a kind of preparation method curing ARR medicament pill, step (5) was pulverized 80-140 mesh sieve and (preferably, was pulverized 100-120 mesh sieve; Be more preferably, pulverized 110 mesh sieves).
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Radix Angelicae Sinensis: base is former: be the root of umbelliferae angelica.Nature and flavor: sweet, acrid, warm.Gui Jing: return liver, the heart, spleen channel.Function cures mainly: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.
Rhodobryum roseum Limpr.: base is former: be the herb of the red great Ye moss of Bryaceae plant.Nature and flavor: pungent, bitter are flat.Function cures mainly: tranquilizing by nourishing the heart, liver heat removing and eyesight improving.For severe palpitation, neurasthenia, conjunctival congestion and swelling pain is controlled in external.
Radix Cynanchi Amplexicaulis: base is former: be root or the herb of asclepiadaceae plant Radix Cynanchi Amplexicaulis.Nature and flavor: micro-hardship are flat, nontoxic.Function cures mainly: heat clearing away, wind-damp dispelling, subduing swelling and detoxicating.Control acute gastroenteritis, acute hepatitis, rheumatalgia, migraine, have blood in stool, carbuncle, eczema.
Herba Desmodii sequacis: base is former: be the herb of leguminous plant ripple leaf Desmodium racemosum Thunb..Nature and flavor: micro-bitterness are flat, nontoxic.Gui Jing: Liver Channel.Function cures mainly: clearing away heat-fire, blood circulation promoting and blood stasis dispelling, sore.The hot conjunctival congestion of main air, retention of placenta, blood stasis amenorrhea, burn.
Rhizoma Acori Graminei: base is former: be the rhizome of South, sky section phytobezoar Rhizoma Acori Graminei.Nature and flavor: pungent, bitter, temperature.Gui Jing: GUIXIN, stomach warp.Function cures mainly: removing dampness is whetted the appetite, eliminating phlegm of having one's ideas straightened out, refreshment Fructus Alpiniae Oxyphyllae.Not hungry for gastral cavity painful abdominal mass, a mouthful dysentery of keeping silent, coma epilepsy, forgetful deafness.
Stigma Croci: base is former: be the stigma of irides Stigma Croci.Nature and flavor: property is put down, sweet in the mouth.Gui Jing: the heart, Liver Channel.Function cures mainly: blood circulation promoting and blood stasis dispelling, removing pathogenic heat from blood and toxic substance from the body, resolving stagnation for tranquilization., palpitation with fear vexed for amenorrhea lump in the abdomen, postpartum stagnation, maculae caused by violent heat pathogen, melancholy painful abdominal mass is gone mad.
Radix Clerodenri Cyrtophylli: base is former: be the root of Verbenaceae Herba Diclipterae Chinensis.Nature and flavor: bitter, cold.Function cures mainly: heat clearing away, and removing toxic substances, dispels the wind, dehumidifying.Control encephalitis b, epidemic encephalitis, the high heat of flu, headache, enteritis, dysentery, jaundice, toothache, epistaxis, laryngopharynx swelling and pain.
Fructus Choerospondiatis: base is former: be fresh fruit or the pit of Anacardiaceae plant Fructus Choerospondiatis.Nature and flavor: sour and astringent are cool.Function cures mainly: removing toxic substances, convergence, pain relieving, hemostasis.For burn and scald, traumatic hemorrhage, psoriasis.
Flos Epiphylli Oxypetali: base is former: be the flower of Cactaeous plants Flos Epiphylli Oxypetali.Nature and flavor: flat, light.Function cures mainly: lung heat clearing, and cough-relieving is reduced phlegm.Control heart peratodynia, spit blood, be most suitable for pulmonary tuberculosis.
Caulis te Folium Callicarpae Longissimae: base is former: be the leaf of Verbenaceae Caulis te Folium Callicarpae Longissimae.Nature and flavor: pungent, temperature.Function cures mainly: expelling wind and cold, sterilization of invigorating blood circulation.Dispelling the wind and dampness pathogens osteodynia, cough due to wind and cold, abdominal pain due to accumulation of cold, innominate toxic swelling, traumatic injury.
Ramulus Cinnamomi: base is former: be the twig of canella Cortex Cinnamomi.Nature and flavor: acrid, sweet, warm.Gui Jing: GUIXIN, lung, urinary bladder channel.Function cures mainly: diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the flat gas that spins.For anemofrigid cold, coldness and pain in the epigastrium, cold in blood amenorrhea, arthralgia, phlegm retention, edema, cardiopalmus, renal mass.
Fructus Hordei Germinatus: base is former: be the Fructus Hordei Vulgaris caryopsis germinateed.Nature and flavor: sweet, tepor.Gui Jing: enter spleen, stomach warp.Function cures mainly: help digestion, and in, the therapeutic method to keep the adverse QI flowing downwards.Control food stagnation not disappear, distension and fullness in the abdomen, inappetence, vomiting is had loose bowels, and mammary swelling does not disappear.
Caulis Bauhihiae Championii: base is former: be the stem of leguminous plant Caulis Bauhiniae Championii.Nature and flavor: toil are flat, nontoxic.Function cures mainly: dispel the wind, blood stasis removing, pain relieving.Dispelling the wind and dampness pathogens osteodynia, traumatic injury synthetism.
Radix Ophiopogonis: base is former: be the tuber of liliaceous plant dwarf lilyturf.Nature and flavor: sweet micro-hardship, cold.Gui Jing: enter lung, stomach, heart channel.Function cures mainly: YIN nourishing and the production of body fluid promoting, and lung moistening clears away heart-fire.For dryness of the lung dry cough.Chronic consumptive disease is coughed, and Tianjin wound is thirsty, and vexed insomnia, interior-heat is quenched one's thirst, dryness of the intestine constipation, pharyngeal diphtheria.
Rhizoma disporopsis pernyi: base is former: be the rhizome of the false cantonese fairy bells of liliaceous plant sword-like leave.Nature and flavor: sweet are flat.Function cures mainly: nourishing YIN and moistening the lung, promoting the production of body fluid to quench thirst.Hyperhidrosis is coughed, xerostomia, puerperal asthenia for void.
It is simple that one provided by the invention cures ARR medicament preparation method, and taking convenience, is easy to carry.In addition, excellent results of the present invention also shows:
1, good effect of the present invention, untoward reaction is low, and safety is high, can clinical expansion;
2, this prescription is developed in conjunction with Chinese medicine principle by clinical experience for many years, the effect such as have supplementing QI and nourishing YIN, mind calming is promoted blood circulation;
3, medicine source of the present invention is wide, and cost is low, and long-term taking is without financial burden.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
embodiment 1the ARR medicament of a kind for the treatment of, is prepared from (every part of 10g) primarily of following bulk drugs: Radix Angelicae Sinensis 12 parts, Rhodobryum roseum Limpr. 10 parts, Radix Cynanchi Amplexicaulis 8 parts, Herba Desmodii sequacis 6 parts, Rhizoma Acori Graminei 9 parts, Stigma Croci 8 parts, Radix Clerodenri Cyrtophylli 10 parts, Fructus Choerospondiatis 11 parts, Flos Epiphylli Oxypetali 9 parts, Caulis te Folium Callicarpae Longissimae 7 parts, Ramulus Cinnamomi 10 parts, 9 parts, Fructus Hordei Germinatus, Caulis Bauhihiae Championii 7 parts, Radix Ophiopogonis 10 parts, Rhizoma disporopsis pernyi 8 parts.
Above-mentioned a kind of preparation method curing ARR drug capsule agent is:
(1) get Rhodobryum roseum Limpr. sucrose solution on the rocks to boil, the amount of crystal sugar water is 2 times of Rhodobryum roseum Limpr. quality, boils when exhausting to water, takes out, dries, dry in the air cool;
(2) by Fructus Hordei Germinatus and Radix Ophiopogonis, clean, be placed in frying pan, add propagandize hotly to crude drug surface yellowish-brown time, mix thoroughly with Sucus Zingberis, treat juice exhaust take out, dry;
(3) get Stigma Croci and add yellow wine and refined honey is mixed thoroughly, moistening, load and steam in cup, Steam by water bath exhausts to soup, Guan Huo, cools, and takes out, dries, pulverize together with step (1) (2) made crude drug;
(4) Radix Angelicae Sinensis, Radix Cynanchi Amplexicaulis, Herba Desmodii sequacis, Rhizoma Acori Graminei, Radix Clerodenri Cyrtophylli, Fructus Choerospondiatis, Flos Epiphylli Oxypetali, Caulis te Folium Callicarpae Longissimae, Ramulus Cinnamomi, Caulis Bauhihiae Championii and Rhizoma disporopsis pernyi roguing are cleaned, decoct with water three times, decoct with water 7 times that institute's amount of water is boiled crude drug quality at every turn, first time big fire boils 30 minutes, second time big fire boils 25 minutes, and third time big fire boils 20 minutes, filters, collect filtrate, merge three gained filtrates;
(5) join in step (4) made filtrate by step (3) made medicated powder, concentrated, dry, pulverize, incapsulate, every capsules loads medicated powder 0.35g, obtains capsule.
embodiment 2the ARR medicament of a kind for the treatment of, is prepared from (every part of 10g) primarily of following bulk drugs: Radix Angelicae Sinensis 18 parts, Rhodobryum roseum Limpr. 16 parts, Radix Cynanchi Amplexicaulis 13 parts, Herba Desmodii sequacis 12 parts, Rhizoma Acori Graminei 13 parts, Stigma Croci 12 parts, Radix Clerodenri Cyrtophylli 13 parts, Fructus Choerospondiatis 15 parts, Flos Epiphylli Oxypetali 14 parts, Caulis te Folium Callicarpae Longissimae 12 parts, Ramulus Cinnamomi 14 parts, 15 parts, Fructus Hordei Germinatus, Caulis Bauhihiae Championii 13 parts, Radix Ophiopogonis 16 parts, Rhizoma disporopsis pernyi 14 parts.
A kind of preparation method curing ARR medicament powder is:
(1) get Rhodobryum roseum Limpr. sucrose solution on the rocks to boil, the amount of crystal sugar water is 2 times of Rhodobryum roseum Limpr. quality, boils when exhausting to water, takes out, dries, dry in the air cool;
(2) by Fructus Hordei Germinatus and Radix Ophiopogonis, clean, be placed in frying pan, add propagandize hotly to crude drug surface yellowish-brown time, mix thoroughly with Sucus Zingberis, treat juice exhaust take out, dry;
(3) get Stigma Croci and add yellow wine and refined honey is mixed thoroughly, moistening, load and steam in cup, Steam by water bath exhausts to soup, Guan Huo, cools, and takes out, dries, pulverized 140 mesh sieves together with step (1) (2) made crude drug;
(4) Radix Angelicae Sinensis, Radix Cynanchi Amplexicaulis, Herba Desmodii sequacis, Rhizoma Acori Graminei, Radix Clerodenri Cyrtophylli, Fructus Choerospondiatis, Flos Epiphylli Oxypetali, Caulis te Folium Callicarpae Longissimae, Ramulus Cinnamomi, Caulis Bauhihiae Championii and Rhizoma disporopsis pernyi roguing are cleaned, decoct with water three times, decoct with water 7 times that institute's amount of water is boiled crude drug quality at every turn, first time big fire boils 30 minutes, second time big fire boils 25 minutes, and third time big fire boils 20 minutes, filters, collect filtrate, merge three gained filtrates;
(5) by step (4) made filtrate, concentrated, dry, pulverize, medicated powder stirring and evenly mixing made with step (3), obtains powder.
Model case: xxx, man, 43 years old.Medical history: ventricular premature contraction 5 years, nearly half a year often feels sensation of oppression and faint pain in the chest, and cardiopalmus is had palpitation, and breathes hard, weak, sleep disorder, dream is many, and increase the weight of two weeks, examination in hospital, body of the tongue is dim, yellow fur, the thin string of rapid pulse, pulse frequency 112 times/min, occasionally has premature beat, and electrocardiogram display tachycardia, is diagnosed as cardiopalmus.
Take the present embodiment gained one and cure ARR medicament powder, each 4-6g, every day 3 times, warm boiled water, 10 days courses for the treatment of.After taking a course for the treatment of, cardiopalmus is nervous to be improved, and pulse frequency is down to 96 times/min, after taking two courses for the treatment of, sleep recovers normal, and cardiopalmus is had palpitation, breathe hard, weak obvious improvement, after taking three courses for the treatment of, malaise symptoms is eliminated substantially, consolidate after taking two courses for the treatment of, all diseases of patient disappear entirely, and pulse frequency is down to 58-63 time/min, patient fully recovers, and follows up a case by regular visits to and do not recur after 1 year.
embodiment 3the ARR medicament of a kind for the treatment of, is prepared from (every part of 10g) primarily of following bulk drugs: Radix Angelicae Sinensis 14 parts, Rhodobryum roseum Limpr. 12 parts, Radix Cynanchi Amplexicaulis 9 parts, Herba Desmodii sequacis 8 parts, Rhizoma Acori Graminei 10 parts, Stigma Croci 9 parts, Radix Clerodenri Cyrtophylli 11 parts, Fructus Choerospondiatis 12 parts, Flos Epiphylli Oxypetali 10 parts, Caulis te Folium Callicarpae Longissimae 8 parts, Ramulus Cinnamomi 11 parts, 10 parts, Fructus Hordei Germinatus, Caulis Bauhihiae Championii 9 parts, Radix Ophiopogonis 12 parts, Rhizoma disporopsis pernyi 10 parts.
A kind of preparation method curing ARR medicament decoction is:
(1) get Rhodobryum roseum Limpr. sucrose solution on the rocks to boil, the amount of crystal sugar water is 5 times of Rhodobryum roseum Limpr. quality, boils when reducing by half to water, filters, and collects filtrate;
(2) by Fructus Hordei Germinatus and Radix Ophiopogonis, clean, be placed in frying pan, add propagandize hotly to crude drug surface yellowish-brown time, mix thoroughly with Sucus Zingberis, treat juice exhaust take out, dry;
(3) get Stigma Croci and add yellow wine and refined honey is mixed thoroughly, moistening, load and steam in cup, Steam by water bath exhausts to soup, Guan Huo, cools, and takes out, dries, and pulverizes, makes medicated powder;
(4) Radix Angelicae Sinensis, Radix Cynanchi Amplexicaulis, Herba Desmodii sequacis, Rhizoma Acori Graminei, Radix Clerodenri Cyrtophylli, Fructus Choerospondiatis, Flos Epiphylli Oxypetali, Caulis te Folium Callicarpae Longissimae, Ramulus Cinnamomi, Caulis Bauhihiae Championii and Rhizoma disporopsis pernyi roguing are cleaned, decoct with water together with step (2) made crude drug, first time big fire is boiled rear little fire and is decocted 34 minutes, second time big fire is boiled rear little fire and is decocted 26 minutes, decoct 7 times that amount of water is boiled crude drug quality for twice, filter, collect, and merge twice gained filtrate;
(5) step (1) and step (4) made filtrate are merged, add step (3) made medicated powder, mixing, obtains decoction.
Model case: xxx, man, 56 years old.Main suit: often to supper, normal sense cardiopalmus was had palpitation, palpitating speed, and it is dizzy that companion is slight because of caused by fatigue in nearly two months, the whole body is weak, spontaneous perspiration, poor appetite, examination in hospital, light red tongue, white and thin fur, weak pulse and counting, electrocardiogram display arrhythmia, heart rate 118/min, is diagnosed as cardiopalmus.
Take the present embodiment gained one and cure ARR medicament decoction, adopt every day 3 times, each 300-400ml, warm, 10 days courses for the treatment of.After taking one week, spirit takes a turn for the better, and weakly alleviates, and cardiopalmus seizure frequency of having palpitation reduces, and after taking two courses for the treatment of, patient mental is good, and have palpitation without cardiopalmus, heart rate returns to 60-65/min, and patient's recovery from illness, two courses for the treatment of are taken in rear consolidation, follow up a case by regular visits to and do not recur after 1 year.
embodiment 4the ARR medicament of a kind for the treatment of, is prepared from (every part of 10g) primarily of following bulk drugs: Radix Angelicae Sinensis 16 parts, Rhodobryum roseum Limpr. 14 parts, Radix Cynanchi Amplexicaulis 12 parts, Herba Desmodii sequacis 10 parts, Rhizoma Acori Graminei 12 parts, Stigma Croci 11 parts, Radix Clerodenri Cyrtophylli 12 parts, Fructus Choerospondiatis 14 parts, Flos Epiphylli Oxypetali 13 parts, Caulis te Folium Callicarpae Longissimae 11 parts, Ramulus Cinnamomi 13 parts, 14 parts, Fructus Hordei Germinatus, Caulis Bauhihiae Championii 11 parts, Radix Ophiopogonis 14 parts, Rhizoma disporopsis pernyi 12 parts.
A kind of preparation method curing ARR medicament pill is:
(1) get Rhodobryum roseum Limpr. sucrose solution on the rocks to boil, the amount of crystal sugar water is 2 times of Rhodobryum roseum Limpr. quality, boils when exhausting to water, takes out, dries, dry in the air cool;
(2) by Fructus Hordei Germinatus and Radix Ophiopogonis, clean, be placed in frying pan, add propagandize hotly to crude drug surface yellowish-brown time, mix thoroughly with Sucus Zingberis, treat juice exhaust take out, dry;
(3) get Stigma Croci and add yellow wine and refined honey is mixed thoroughly, moistening, load and steam in cup, Steam by water bath exhausts to soup, Guan Huo, cools, and takes out, dries, pulverize together with step (1) (2) made crude drug;
(4) Radix Angelicae Sinensis, Radix Cynanchi Amplexicaulis, Herba Desmodii sequacis, Rhizoma Acori Graminei, Radix Clerodenri Cyrtophylli, Fructus Choerospondiatis, Flos Epiphylli Oxypetali, Caulis te Folium Callicarpae Longissimae, Ramulus Cinnamomi, Caulis Bauhihiae Championii and Rhizoma disporopsis pernyi roguing are cleaned, decoct with water three times, decoct with water 7 times that institute's amount of water is boiled crude drug quality at every turn, first time big fire boils 30 minutes, second time big fire boils 25 minutes, and third time big fire boils 20 minutes, filters, collect filtrate, merge three gained filtrates;
(5) by step (4) made filtrate, concentrated, dry, pulverize 110 mesh sieves, medicated powder stirring and evenly mixing made with step (3), and added water and generally make ball, obtain pill.
Model case: xxx, female, 32 years old.Main suit: often feel shortness of breath and palpitation in nearly four months, does not uncomfortable in chestly relax, companion's dripping sweat, increase the weight of after fatigue, nearly two weeks exacerbation of symptoms, increased frequency that palpitation of the heart comes on, in bed can because of uncomfortable in chest and awake, spiritlessness and weakness, loss of appetite, examination in hospital, enlarged tongue is tender, and matter redness is light, white and thin fur, slow pulse is weak, electrocardiogram display sinus bradycardia, heart rate 46 times/min, other every inspections are all normal, are diagnosed as cardiopalmus.
Take the present embodiment gained one and cure ARR medicament pill, adopt every day 3 times, each 4, with warm water delivery service, 10 days courses for the treatment of.After taking a course for the treatment of, cardiopalmus, breathe hard, uncomfortable in chestly obviously to alleviate, attack times and time decreased, heart rate accelerates, and after taking three courses for the treatment of, all diseases disappear entirely, and heart rate recovers normal, and patient fully recovers, and two courses for the treatment of are taken in rear consolidation, follow up a case by regular visits to and do not recur after 1 year.
embodiment 5the ARR medicament of a kind for the treatment of, is prepared from (every part of 10g) primarily of following bulk drugs: Radix Angelicae Sinensis 15 parts, Rhodobryum roseum Limpr. 13 parts, Radix Cynanchi Amplexicaulis 10.5 parts, Herba Desmodii sequacis 9 parts, Rhizoma Acori Graminei 11 parts, Stigma Croci 10 parts, Radix Clerodenri Cyrtophylli 11.5 parts, Fructus Choerospondiatis 13 parts, Flos Epiphylli Oxypetali 11.5 parts, Caulis te Folium Callicarpae Longissimae 9.5 parts, Ramulus Cinnamomi 12 parts, 12 parts, Fructus Hordei Germinatus, Caulis Bauhihiae Championii 10 parts, Radix Ophiopogonis 13 parts, Rhizoma disporopsis pernyi 11 parts.
A kind of preparation method curing ARR drug capsule agent is:
(1) get Rhodobryum roseum Limpr. sucrose solution on the rocks to boil, the amount of crystal sugar water is 2 times of Rhodobryum roseum Limpr. quality, boils when exhausting to water, takes out, dries, dry in the air cool;
(2) by Fructus Hordei Germinatus and Radix Ophiopogonis, clean, be placed in frying pan, add propagandize hotly to crude drug surface yellowish-brown time, mix thoroughly with Sucus Zingberis, treat juice exhaust take out, dry;
(3) get Stigma Croci and add yellow wine and refined honey is mixed thoroughly, moistening, load and steam in cup, Steam by water bath exhausts to soup, Guan Huo, cools, and takes out, dries, pulverize together with step (1) (2) made crude drug;
(4) Radix Angelicae Sinensis, Radix Cynanchi Amplexicaulis, Herba Desmodii sequacis, Rhizoma Acori Graminei, Radix Clerodenri Cyrtophylli, Fructus Choerospondiatis, Flos Epiphylli Oxypetali, Caulis te Folium Callicarpae Longissimae, Ramulus Cinnamomi, Caulis Bauhihiae Championii and Rhizoma disporopsis pernyi roguing are cleaned, decoct with water three times, decoct with water 7 times that institute's amount of water is boiled crude drug quality at every turn, first time big fire boils 30 minutes, second time big fire boils 25 minutes, and third time big fire boils 20 minutes, filters, collect filtrate, merge three gained filtrates;
(5) join in step (4) made filtrate by step (3) made medicated powder, concentrated, dry, pulverize, incapsulate, every capsules loads medicated powder 0.35g, obtains capsule.
test example 1gained one of the present invention cures the clinical practice of ARR medicament (embodiment 5):
In January ,-2014 in October, 2012, in the patient of 5 heart internal medicine in hospital diagnosis and treatment, filter out patient 328 example, wherein women 161 example, male 167 example, age 45-67 year, the mean age (54.7 ± 3.2) year, course of disease 0.5-5, average course of disease (2.8 ± 0.4) year.All patients are all diagnosed as arrhythmia through electrocardiogram and 24h dynamic ecg recordings examination.Get rid of the factor institute proarrhythmia such as acid base imbalance and electrolyte disturbance, digitalism, hypotension, cardiogenic shock, II to III degree heart block, sick sinus syndrome and severe sinus bradycardia in body.
Patient is divided into two groups at random, experimental group 185 example and matched group 143 routine, two groups in sex, age, the course of disease, the state of an illness etc. without significant difference (P > 0.05), there is comparability.Experimental group takes products obtained therefrom of the present invention, taken three times a day, each 2-4 (adjusting to some extent depending on concrete condition), 10 days courses for the treatment of, treats 4 courses for the treatment of continuously.Matched group takes other medicine as conventional medication such as heart nourishing palpitation stabilizing capsule, TONGMAIYANGXINWAN, sharp heart balls.Period in a medicine carries out Continuous Observation to two groups of patients, record symptom and change.
Curative effect situation criterion: effective: the symptoms such as arrhythmia disappear substantially, duration of seizure and number of times reduce more than 90%, and electrocardiogram and ambulatory electrocardiogram recover normal substantially; Effective: the symptoms such as arrhythmia take a turn for the better, duration of seizure and number of times reduce more than 50%, and electrocardiogram makes moderate progress, and is tending towards normal; Invalid: the symptoms such as arrhythmia are not improved or increase the weight of, Electrocardioscopy is unchanged or increase the weight of.
Table 1 liang group patient treatment situation contrast
Through treatment, two groups of patient treatment situations are as shown in table 1, therefrom known experimental group, effective 123 examples, effective 54 examples, total effective rate is 95.7%, matched group, effective 62 examples, effective 51 examples, total effective rate is 79.0%, it can thus be appreciated that the therapeutic effect of experimental group is better than matched group.In therapeutic process, experimental group has 3 routine patients to occur dizziness, and vomiting appears in 1 example, and after drug withdrawal, symptom disappears automatically, and matched group has 4 routine patients to occur bradycardia, and 1 example occurs dizzy.Above-mentioned symptom is all comparatively light, and the damage of internal organs does not occur.
The present invention selects Chinese angelica blood supplementing to invigorate blood circulation, Rhodobryum roseum Limpr. tranquilizing by nourishing the heart, Radix Cynanchi Amplexicaulis heat-clearing and toxic substances removing, Herba Desmodii sequacis's clearing away heat-fire, Rhizoma Acori Graminei refreshment Fructus Alpiniae Oxyphyllae, Stigma Croci resolving stagnation for tranquilization, Radix Clerodenri Cyrtophylli expelling wind and removing dampness, Fructus Choerospondiatis removing toxic substances hemostasis, Flos Epiphylli Oxypetali relieving cough and resolving phlegm, Caulis te Folium Callicarpae Longissimae expelling wind and cold, Ramulus Cinnamomi promoting the flow of QI-blood by warming the meridian, Fructus Hordei Germinatus help digestion and in, Caulis Bauhihiae Championii dispels the wind blood stasis dispelling, Radix Ophiopogonis YIN nourishing and the production of body fluid promoting, Rhizoma disporopsis pernyi nourishing YIN and moistening the lung, various plants medical material share, and compatibility is precise and appropriate, the effect such as can play supplementing QI and nourishing YIN, mind calming is promoted blood circulation.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.
Claims (10)
1. cure an ARR medicament, it is characterized in that, be prepared from primarily of following bulk drugs, be mass parts: Radix Angelicae Sinensis 12-18, Rhodobryum roseum Limpr. 10-16, Radix Cynanchi Amplexicaulis 8-13, Herba Desmodii sequacis 6-12, Rhizoma Acori Graminei 9-13, Stigma Croci 8-12, Radix Clerodenri Cyrtophylli 10-13, Fructus Choerospondiatis 11-15, Flos Epiphylli Oxypetali 9-14, Caulis te Folium Callicarpae Longissimae 7-12, Ramulus Cinnamomi 10-14, Fructus Hordei Germinatus 9-15, Caulis Bauhihiae Championii 7-13, Radix Ophiopogonis 10-16, Rhizoma disporopsis pernyi 8-14.
2. the ARR medicament of a kind for the treatment of as claimed in claim 1, it is characterized in that, Radix Angelicae Sinensis 14-16, Rhodobryum roseum Limpr. 12-14, Radix Cynanchi Amplexicaulis 9-12, Herba Desmodii sequacis 8-10, Rhizoma Acori Graminei 10-12, Stigma Croci 9-11, Radix Clerodenri Cyrtophylli 11-12, Fructus Choerospondiatis 12-14, Flos Epiphylli Oxypetali 10-13, Caulis te Folium Callicarpae Longissimae 8-11, Ramulus Cinnamomi 11-13, Fructus Hordei Germinatus 10-14, Caulis Bauhihiae Championii 9-11, Radix Ophiopogonis 12-14, Rhizoma disporopsis pernyi 10-12 is (preferred, Radix Angelicae Sinensis 15, Rhodobryum roseum Limpr. 13, Radix Cynanchi Amplexicaulis 10.5, Herba Desmodii sequacis 9, Rhizoma Acori Graminei 11, Stigma Croci 10, Radix Clerodenri Cyrtophylli 11.5, Fructus Choerospondiatis 13, Flos Epiphylli Oxypetali 11.5, Caulis te Folium Callicarpae Longissimae 9.5, Ramulus Cinnamomi 12, Fructus Hordei Germinatus 12, Caulis Bauhihiae Championii 10, Radix Ophiopogonis 13, Rhizoma disporopsis pernyi 11).
3. the one as described in as arbitrary in claim 1-2 cures ARR medicament, and it is characterized in that, be made into pharmaceutically acceptable capsule, its preparation method is:
(1) get Rhodobryum roseum Limpr. sucrose solution on the rocks to boil, the amount of crystal sugar water is 2 times of Rhodobryum roseum Limpr. quality, boils when exhausting to water, takes out, dries, dry in the air cool;
(2) by Fructus Hordei Germinatus and Radix Ophiopogonis, clean, be placed in frying pan, add propagandize hotly to crude drug surface yellowish-brown time, mix thoroughly with Sucus Zingberis, treat juice exhaust take out, dry;
(3) get Stigma Croci and add yellow wine and refined honey is mixed thoroughly, moistening, load and steam in cup, Steam by water bath exhausts to soup, Guan Huo, cools, and takes out, dries, pulverize together with step (1) (2) made crude drug;
(4) Radix Angelicae Sinensis, Radix Cynanchi Amplexicaulis, Herba Desmodii sequacis, Rhizoma Acori Graminei, Radix Clerodenri Cyrtophylli, Fructus Choerospondiatis, Flos Epiphylli Oxypetali, Caulis te Folium Callicarpae Longissimae, Ramulus Cinnamomi, Caulis Bauhihiae Championii and Rhizoma disporopsis pernyi roguing are cleaned, decoct with water three times, first time big fire boils 30 minutes, second time big fire boils 25 minutes, third time big fire boils 20 minutes, filter, collect filtrate, merge three gained filtrates;
(5) join in step (4) made filtrate by step (3) made medicated powder, concentrated, dry, pulverize, incapsulate, every capsules loads medicated powder 0.35g, obtains capsule.
4. a kind of preparation method curing ARR drug capsule agent as claimed in claim 3, it is characterized in that, step (4) decocts with water the 6-8 that institute's amount of water is boiled crude drug quality at every turn, and doubly (preferred, the 6.5-7.5 that institute's amount of water is boiled crude drug quality doubly; Be more preferably, institute's amount of water is 7 times of boiled crude drug quality).
5. the one as described in as arbitrary in claim 1-2 cures ARR medicament, and it is characterized in that, be made into pharmaceutically acceptable powder, its preparation method is:
(1) get Rhodobryum roseum Limpr. sucrose solution on the rocks to boil, the amount of crystal sugar water is 2 times of Rhodobryum roseum Limpr. quality, boils when exhausting to water, takes out, dries, dry in the air cool;
(2) by Fructus Hordei Germinatus and Radix Ophiopogonis, clean, be placed in frying pan, add propagandize hotly to crude drug surface yellowish-brown time, mix thoroughly with Sucus Zingberis, treat juice exhaust take out, dry;
(3) get Stigma Croci and add yellow wine and refined honey is mixed thoroughly, moistening, load and steam in cup, Steam by water bath exhausts to soup, Guan Huo, cools, and takes out, dries, pulverize together with step (1) (2) made crude drug;
(4) Radix Angelicae Sinensis, Radix Cynanchi Amplexicaulis, Herba Desmodii sequacis, Rhizoma Acori Graminei, Radix Clerodenri Cyrtophylli, Fructus Choerospondiatis, Flos Epiphylli Oxypetali, Caulis te Folium Callicarpae Longissimae, Ramulus Cinnamomi, Caulis Bauhihiae Championii and Rhizoma disporopsis pernyi roguing are cleaned, decoct with water three times, decoct with water 7 times that institute's amount of water is boiled crude drug quality at every turn, first time big fire boils 30 minutes, second time big fire boils 25 minutes, and third time big fire boils 20 minutes, filters, collect filtrate, merge three gained filtrates;
(5) by step (4) made filtrate, concentrated, dry, pulverize, medicated powder stirring and evenly mixing made with step (3), obtains powder.
6. a kind of preparation method curing ARR medicament powder as claimed in claim 5, is characterized in that, step (3) was pulverized 100-180 mesh sieve and (preferably, pulverized 120-160 mesh sieve; Be more preferably, pulverized 140 mesh sieves).
7. the one as described in as arbitrary in claim 1-2 cures ARR medicament, and it is characterized in that, be made into pharmaceutically acceptable decoction, its preparation method is:
(1) get Rhodobryum roseum Limpr. sucrose solution on the rocks to boil, the amount of crystal sugar water is 5 times of Rhodobryum roseum Limpr. quality, boils when reducing by half to water, filters, and collects filtrate;
(2) by Fructus Hordei Germinatus and Radix Ophiopogonis, clean, be placed in frying pan, add propagandize hotly to crude drug surface yellowish-brown time, mix thoroughly with Sucus Zingberis, treat juice exhaust take out, dry;
(3) get Stigma Croci and add yellow wine and refined honey is mixed thoroughly, moistening, load and steam in cup, Steam by water bath exhausts to soup, Guan Huo, cools, and takes out, dries, and pulverizes, makes medicated powder;
(4) Radix Angelicae Sinensis, Radix Cynanchi Amplexicaulis, Herba Desmodii sequacis, Rhizoma Acori Graminei, Radix Clerodenri Cyrtophylli, Fructus Choerospondiatis, Flos Epiphylli Oxypetali, Caulis te Folium Callicarpae Longissimae, Ramulus Cinnamomi, Caulis Bauhihiae Championii and Rhizoma disporopsis pernyi roguing are cleaned, decoct with water together with step (2) made crude drug, first time big fire is boiled rear little fire and is decocted 30-38 minute (preferably, little fire decocts 34 minutes), second time big fire is boiled rear little fire and is decocted, and decocts 7 times that amount of water is boiled crude drug quality for twice, filters, collect, and merge twice gained filtrate;
(5) step (1) and step (4) made filtrate are merged, add step (3) made medicated powder, mixing, obtains decoction.
8. a kind of preparation method curing ARR medicament decoction as claimed in claim 7, is characterized in that, the big fire of step (4) second time is boiled rear little fire and decocted 22-30 minute (preferred, little fire decocts 26 minutes).
9. the one as described in as arbitrary in claim 1-2 cures ARR medicament, and it is characterized in that, be made into pharmaceutically acceptable pill, its preparation method is:
(1) get Rhodobryum roseum Limpr. sucrose solution on the rocks to boil, the amount of crystal sugar water is 2 times of Rhodobryum roseum Limpr. quality, boils when exhausting to water, takes out, dries, dry in the air cool;
(2) by Fructus Hordei Germinatus and Radix Ophiopogonis, clean, be placed in frying pan, add propagandize hotly to crude drug surface yellowish-brown time, mix thoroughly with Sucus Zingberis, treat juice exhaust take out, dry;
(3) get Stigma Croci and add yellow wine and refined honey is mixed thoroughly, moistening, load and steam in cup, Steam by water bath exhausts to soup, Guan Huo, cools, and takes out, dries, pulverize together with step (1) (2) made crude drug;
(4) Radix Angelicae Sinensis, Radix Cynanchi Amplexicaulis, Herba Desmodii sequacis, Rhizoma Acori Graminei, Radix Clerodenri Cyrtophylli, Fructus Choerospondiatis, Flos Epiphylli Oxypetali, Caulis te Folium Callicarpae Longissimae, Ramulus Cinnamomi, Caulis Bauhihiae Championii and Rhizoma disporopsis pernyi roguing are cleaned, decoct with water three times, decoct with water 7 times that institute's amount of water is boiled crude drug quality at every turn, first time big fire boils 30 minutes, second time big fire boils 25 minutes, and third time big fire boils 20 minutes, filters, collect filtrate, merge three gained filtrates;
(5) by step (4) made filtrate, concentrated, dry, pulverize, medicated powder stirring and evenly mixing made with step (3), add water and generally make ball, obtain pill.
10. a kind of preparation method curing ARR medicament pill as claimed in claim 9, is characterized in that, step (5) was pulverized 80-140 mesh sieve and (preferably, pulverized 100-120 mesh sieve; Be more preferably, pulverized 110 mesh sieves).
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004149494A (en) * | 2002-11-01 | 2004-05-27 | Morinaga & Co Ltd | Capsinoid-containing composition |
| CN104758587A (en) * | 2015-03-26 | 2015-07-08 | 赵世明 | Traditional Chinese medicine composition for treating arrhythmia |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004149494A (en) * | 2002-11-01 | 2004-05-27 | Morinaga & Co Ltd | Capsinoid-containing composition |
| CN104758587A (en) * | 2015-03-26 | 2015-07-08 | 赵世明 | Traditional Chinese medicine composition for treating arrhythmia |
Non-Patent Citations (1)
| Title |
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| 辛丽等: "中药抗心律失常作用机制的临床研究概况", 《中国老年学杂志》 * |
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Address after: 810000 Qinghai Province, Eastern District of Xining City Garden No. 21 North Street, building 3, Oriental Pearl 2-501 Applicant after: Huo Tongyan Address before: 250000 Shandong, Ji'nan, East Industrial and Commercial Road Flyover District No. 13 Applicant before: Huo Tongyan |
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