CN105055990A - Nerve-calming and depression-relieving medicine and preparation method thereof - Google Patents
Nerve-calming and depression-relieving medicine and preparation method thereof Download PDFInfo
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Abstract
The invention relates to a nerve-calming and depression-relieving medicine and a preparation method thereof. The nerve-calming and depression-relieving medicine consists of the following components in parts by mass: 20-30 parts of cinnabar, 20-30 parts of lucid ganoderma, 15-25 parts of cortex albiziae, 15-25 parts of fossil fragments, 10-18 parts of uncaria tomentosa, 8-15 parts of radix ephedrae, 5-12 parts of light wheat, 5-12 parts of rhizoma rehmanniae, 2-8 parts of coix seed, 2-7 parts of radix angelicae, 1-5 parts of blackend swallowwort root, 1-5 parts of radix scrophulariae and 1-5 parts of tomatin. The nerve-calming and depression-relieving medicine provided by the invention has functions of calming nerve, relieving depression and arresting sweating, and has good effects of treating insomnia and relieving depression; and meanwhile, the medicine can be also used for treating symptoms of spontaneous perspiration and night sweat after sleep, so as to improve people's sleep quality.
Description
Technical field
The present invention relates to body care articles for use technical field, particularly relate to one and to calm the nerves resolving depression medicine and preparation method thereof.
Background technology
Along with modern social development is more and more faster, the mental pressure of people is also increasing, and the pressure from various aspects usually makes that people have difficulty in going to sleep, lassitude, has had a strong impact on normal rest, work and life.Probably cause depression when situation is serious, the emotion of patients with depression can from depressed to extremely grieved, and depression of feeling oneself inferior is even pessimistic and worldweary, can have suicidal attempt or behavior.Once suffer from depression, consequence is hardly imaginable.
The kind of existing resolving depression medicine of calming the nerves is a lot of on the market at present, but it is calmed the nerves, resolving depression effect is not high, and cure rate is on the low side, the spontaneous perspiration produced when simultaneously can not treat sleep, the symptom of night sweat.Such as Chinese invention patent (the patent No. 201410335844.1, applying date 2014.07.15) disclose one and to calm the nerves resolving depression Chinese medicine composition, its effective ingredient is prepared from primarily of the raw material of following weight portion: Herba Dendrobii 1 ~ 40 part, Semen Ziziphi Spinosae 5 ~ 40 parts, 2 ~ 40 parts, Poria, Bulbus Lilii 2 ~ 40 parts, Arillus Longan 1 ~ 20 part, 1 ~ 20 part, Fructus Jujubae.Resolving depression Chinese medicine composition of calming the nerves of the present invention is safe, nontoxic, effectively can improve insomnia, and have the antidepressant effect being better than existing Western medicine.
Summary of the invention
the technical problem solved:poor for existing resolving depression medicine therapeutic effect of calming the nerves, not possess treatment spontaneous perspiration, night sweat symptom shortcoming, the invention provides one and to calm the nerves resolving depression medicine and preparation method thereof.
technical scheme:one is calmed the nerves resolving depression medicine, in mass parts containing following composition: 20 ~ 30 parts, Cinnabaris, and Ganoderma 20 ~ 30 parts, Cortex Albiziae 15 ~ 25 parts, Os Draconis 15 ~ 25 parts, Ramulus Uncariae Cum Uncis 10 ~ 18 parts, Radix Ephedrae 8 ~ 15 parts, Fructus Tritici Levis 5 ~ 12 parts, Radix Rehmanniae 5 ~ 12 parts, Semen Coicis 2 ~ 8 parts, the Radix Angelicae Dahuricae 2 ~ 7 parts, Radix Cynanchi Atrati 1 ~ 5 part, Radix Scrophulariae 1 ~ 5 part, licopersicin 1 ~ 5 part.
One described above is calmed the nerves resolving depression medicine, in mass parts containing following composition: 22 ~ 28 parts, Cinnabaris, and Ganoderma 22 ~ 28 parts, Cortex Albiziae 18 ~ 23 parts, Os Draconis 16 ~ 22 parts, Ramulus Uncariae Cum Uncis 12 ~ 15 parts, Radix Ephedrae 9 ~ 14 parts, Fructus Tritici Levis 6 ~ 11 parts, Radix Rehmanniae 7 ~ 12 parts, Semen Coicis 3 ~ 7 parts, the Radix Angelicae Dahuricae 3 ~ 6 parts, Radix Cynanchi Atrati 2 ~ 4 parts, Radix Scrophulariae 2 ~ 4 parts, licopersicin 2 ~ 4 parts.
One described above is calmed the nerves resolving depression medicine, in mass parts containing following composition: 24 parts, Cinnabaris, and Ganoderma 24 parts, Cortex Albiziae 20 parts, Os Draconis 17 parts, Ramulus Uncariae Cum Uncis 13 parts, Radix Ephedrae 10 parts, Fructus Tritici Levis 7 parts, Radix Rehmanniae 8 parts, Semen Coicis 4 parts, the Radix Angelicae Dahuricae 4 parts, Radix Cynanchi Atrati 2.5 parts, Radix Scrophulariae 2.5 parts, licopersicin 2.5 parts.
One described above is calmed the nerves resolving depression medicine, in mass parts containing following composition: 25 parts, Cinnabaris, and Ganoderma 25 parts, Cortex Albiziae 21 parts, Os Draconis 19 parts, Ramulus Uncariae Cum Uncis 14 parts, Radix Ephedrae 12 parts, Fructus Tritici Levis 8.5 parts, Radix Rehmanniae 8.5 parts, Semen Coicis 5 parts, the Radix Angelicae Dahuricae 4.5 parts, Radix Cynanchi Atrati 3 parts, Radix Scrophulariae 3 parts, licopersicin 3 parts.
The preparation method of a kind of resolving depression medicine of calming the nerves described above, the preparation process of the method is as follows:
The first step: Cinnabaris, Ganoderma, Cortex Albiziae, Os Draconis, Ramulus Uncariae Cum Uncis, Radix Ephedrae, Fructus Tritici Levis, Radix Rehmanniae, Semen Coicis, the Radix Angelicae Dahuricae, Radix Cynanchi Atrati, Radix Scrophulariae are cleaned up, fine powder is ground to form respectively after drying, fine powder is crossed 70 ~ 90 mesh sieves, then mix homogeneously, load tea bag;
Second step: by tea bag the 1st use 8 ~ 10 times of soak by water 4 ~ 6h, the 2nd, with 4 ~ 6 times of soak by water 2 ~ 3h, merges 2 decocting liquids, filters and obtains filtrate;
3rd step: add 80 ~ 90% ethanol with filtrate equivalent in filtrate, stirs, and leaves standstill 15-19h, gets supernatant, and after recovery ethanol, the relative density be evaporated to 50 ~ 60 DEG C time is the thick paste of 1.1;
4th step: by thick paste after licopersicin mix homogeneously, makes pill or ointment, is resolving depression medicine of calming the nerves.
In the first step described above, fine powder is crossed 80 mesh sieves.
By tea bag the 1st use 9 times of soak by water 5h in second step described above, the 2nd with 5 times of soak by water 2.5h.
In filtrate, add 85% ethanol with filtrate equivalent in the 3rd step described above, stir, leave standstill 17h, get supernatant, after recovery ethanol, the relative density be evaporated to 55 DEG C time is the thick paste of 1.1.
beneficial effect:one provided by the invention is calmed the nerves resolving depression medicine and preparation method thereof, this resolving depression medical instrument of calming the nerves have calm the nerves, effect of resolving depression, hidroschesis, there is effect of good Cure for insomnia and alleviate depression, effectively can also treat the symptom of spontaneous perspiration after falling asleep, night sweat simultaneously, improve the sleep quality of people.
Detailed description of the invention
embodiment 1
One is calmed the nerves resolving depression medicine, in mass parts containing following composition: 20 parts, Cinnabaris, and Ganoderma 20 parts, Cortex Albiziae 15 parts, Os Draconis 15 parts, Ramulus Uncariae Cum Uncis 10 parts, Radix Ephedrae 8 parts, Fructus Tritici Levis 5 parts, Radix Rehmanniae 5 parts, Semen Coicis 2 parts, the Radix Angelicae Dahuricae 2 parts, Radix Cynanchi Atrati 1 part, Radix Scrophulariae 1 part, licopersicin 1 part.
Calm the nerves the preparation method of resolving depression medicine, the preparation process of the method is as follows:
The first step: Cinnabaris, Ganoderma, Cortex Albiziae, Os Draconis, Ramulus Uncariae Cum Uncis, Radix Ephedrae, Fructus Tritici Levis, Radix Rehmanniae, Semen Coicis, the Radix Angelicae Dahuricae, Radix Cynanchi Atrati, Radix Scrophulariae are cleaned up, grind to form fine powder respectively after drying, crosses 70 mesh sieves, then mix homogeneously by fine powder, load tea bag;
Second step: by tea bag the 1st use 8 times of soak by water 4h, the 2nd, with 4 times of soak by water 2h, merges 2 decocting liquids, filters and obtains filtrate;
3rd step: add 80% ethanol with filtrate equivalent in filtrate, stirs, and leaves standstill 15h, gets supernatant, and after recovery ethanol, the relative density be evaporated to 50 DEG C time is the thick paste of 1.1;
4th step: by thick paste after licopersicin mix homogeneously, makes pill or ointment, is resolving depression medicine of calming the nerves.
embodiment 2
One is calmed the nerves resolving depression medicine, in mass parts containing following composition: 30 parts, Cinnabaris, and Ganoderma 30 parts, Cortex Albiziae 25 parts, Os Draconis 25 parts, Ramulus Uncariae Cum Uncis 18 parts, Radix Ephedrae 15 parts, Fructus Tritici Levis 12 parts, Radix Rehmanniae 12 parts, Semen Coicis 8 parts, the Radix Angelicae Dahuricae 7 parts, Radix Cynanchi Atrati 5 parts, Radix Scrophulariae 5 parts, licopersicin 5 parts.
Calm the nerves the preparation method of resolving depression medicine, the preparation process of the method is as follows:
The first step: Cinnabaris, Ganoderma, Cortex Albiziae, Os Draconis, Ramulus Uncariae Cum Uncis, Radix Ephedrae, Fructus Tritici Levis, Radix Rehmanniae, Semen Coicis, the Radix Angelicae Dahuricae, Radix Cynanchi Atrati, Radix Scrophulariae are cleaned up, grind to form fine powder respectively after drying, crosses 90 mesh sieves, then mix homogeneously by fine powder, load tea bag;
Second step: by tea bag the 1st use 10 times of soak by water 6h, the 2nd, with 6 times of soak by water 3h, merges 2 decocting liquids, filters and obtains filtrate;
3rd step: add 90% ethanol with filtrate equivalent in filtrate, stirs, and leaves standstill 19h, gets supernatant, and after recovery ethanol, the relative density be evaporated to 60 DEG C time is the thick paste of 1.1;
4th step: by thick paste after licopersicin mix homogeneously, makes pill or ointment, is resolving depression medicine of calming the nerves.
embodiment 3
One is calmed the nerves resolving depression medicine, in mass parts containing following composition: 28 parts, Cinnabaris, and Ganoderma 28 parts, Cortex Albiziae 23 parts, Os Draconis 22 parts, Ramulus Uncariae Cum Uncis 15 parts, Radix Ephedrae 14 parts, Fructus Tritici Levis 11 parts, Radix Rehmanniae 12 parts, Semen Coicis 7 parts, the Radix Angelicae Dahuricae 6 parts, Radix Cynanchi Atrati 4 parts, Radix Scrophulariae 4 parts, licopersicin 4 parts.
Calm the nerves the preparation method of resolving depression medicine, the preparation process of the method is as follows:
The first step: Cinnabaris, Ganoderma, Cortex Albiziae, Os Draconis, Ramulus Uncariae Cum Uncis, Radix Ephedrae, Fructus Tritici Levis, Radix Rehmanniae, Semen Coicis, the Radix Angelicae Dahuricae, Radix Cynanchi Atrati, Radix Scrophulariae are cleaned up, grind to form fine powder respectively after drying, crosses 80 mesh sieves, then mix homogeneously by fine powder, load tea bag;
Second step: by tea bag the 1st use 9 times of soak by water 5h, the 2nd, with 5 times of soak by water 2.5h, merges 2 decocting liquids, filters and obtains filtrate;
3rd step: add 85% ethanol with filtrate equivalent in filtrate, stirs, and leaves standstill 17h, gets supernatant, and after recovery ethanol, the relative density be evaporated to 55 DEG C time is the thick paste of 1.1;
4th step: by thick paste after licopersicin mix homogeneously, makes pill or ointment, is resolving depression medicine of calming the nerves.
embodiment 4
One is calmed the nerves resolving depression medicine, in mass parts containing following composition: 24 parts, Cinnabaris, and Ganoderma 24 parts, Cortex Albiziae 20 parts, Os Draconis 17 parts, Ramulus Uncariae Cum Uncis 13 parts, Radix Ephedrae 10 parts, Fructus Tritici Levis 7 parts, Radix Rehmanniae 8 parts, Semen Coicis 4 parts, the Radix Angelicae Dahuricae 4 parts, Radix Cynanchi Atrati 2.5 parts, Radix Scrophulariae 2.5 parts, licopersicin 2.5 parts.
Calm the nerves the preparation method of resolving depression medicine, the preparation process of the method is as follows:
The first step: Cinnabaris, Ganoderma, Cortex Albiziae, Os Draconis, Ramulus Uncariae Cum Uncis, Radix Ephedrae, Fructus Tritici Levis, Radix Rehmanniae, Semen Coicis, the Radix Angelicae Dahuricae, Radix Cynanchi Atrati, Radix Scrophulariae are cleaned up, grind to form fine powder respectively after drying, crosses 80 mesh sieves, then mix homogeneously by fine powder, load tea bag;
Second step: by tea bag the 1st use 9 times of soak by water 5h, the 2nd, with 5 times of soak by water 2.5h, merges 2 decocting liquids, filters and obtains filtrate;
3rd step: add 85% ethanol with filtrate equivalent in filtrate, stirs, and leaves standstill 17h, gets supernatant, and after recovery ethanol, the relative density be evaporated to 55 DEG C time is the thick paste of 1.1;
4th step: by thick paste after licopersicin mix homogeneously, makes pill or ointment, is resolving depression medicine of calming the nerves.
embodiment 5
One is calmed the nerves resolving depression medicine, in mass parts containing following composition: 25 parts, Cinnabaris, and Ganoderma 25 parts, Cortex Albiziae 21 parts, Os Draconis 19 parts, Ramulus Uncariae Cum Uncis 14 parts, Radix Ephedrae 12 parts, Fructus Tritici Levis 8.5 parts, Radix Rehmanniae 8.5 parts, Semen Coicis 5 parts, the Radix Angelicae Dahuricae 4.5 parts, Radix Cynanchi Atrati 3 parts, Radix Scrophulariae 3 parts, licopersicin 3 parts.
Calm the nerves the preparation method of resolving depression medicine, the preparation process of the method is as follows:
The first step: Cinnabaris, Ganoderma, Cortex Albiziae, Os Draconis, Ramulus Uncariae Cum Uncis, Radix Ephedrae, Fructus Tritici Levis, Radix Rehmanniae, Semen Coicis, the Radix Angelicae Dahuricae, Radix Cynanchi Atrati, Radix Scrophulariae are cleaned up, grind to form fine powder respectively after drying, crosses 80 mesh sieves, then mix homogeneously by fine powder, load tea bag;
Second step: by tea bag the 1st use 9 times of soak by water 5h, the 2nd, with 5 times of soak by water 2.5h, merges 2 decocting liquids, filters and obtains filtrate;
3rd step: add 85% ethanol with filtrate equivalent in filtrate, stirs, and leaves standstill 17h, gets supernatant, and after recovery ethanol, the relative density be evaporated to 55 DEG C time is the thick paste of 1.1;
4th step: by thick paste after licopersicin mix homogeneously, makes pill or ointment, is resolving depression medicine of calming the nerves.
comparative example 1
Patent of invention publication number is that the patent of CN104127698A comprises following content:
Calm the nerves the Chinese medicine composition of melancholy-relieving effect, its effective ingredient is prepared from primarily of the raw material of following weight: Herba Dendrobii 2g, Semen Ziziphi Spinosae 10g, Poria 8g, Bulbus Lilii 5g, Arillus Longan 3g, Fructus Jujubae 3g.
A granule obtained by above-mentioned resolving depression Chinese medicine composition of calming the nerves, it is prepared from by the raw material of following weight:
Major ingredient: above-mentioned Chinese medicine composition;
Adjuvant: Mel 10g, sucrose 2g.
The preparation method of above-mentioned granule, comprise the steps: that Herba Dendrobii, Semen Ziziphi Spinosae, Poria, Bulbus Lilii are cured respectively at 60 ~ 80 DEG C by (1), after remove portion moisture, mixed powder is broken into coarse powder; (2) Arillus Longan, Fructus Jujubae are cured respectively at 60 ~ 80 DEG C, after remove portion moisture, join successively in step (1) described coarse powder, mix homogeneously, progressively pulverizes, and crosses 200 mesh sieves, obtains mixed powder; (3) by sucrose drying and crushing at 60 ~ 80 DEG C, and cross 80 mesh sieves, join in step (2) described mixed powder, then add Mel 10g, obtain mixed material; (4) spraying adds the ethanol being equivalent to described mixed material weight 5%, and granulation, dry, 20 order granulate, obtain described granule.
What embodiment 1-5 prepared calm the nerves, and resolving depression medical instrument has good calms the nerves, effect of resolving depression, and has the effect of hidroschesis, and effectively can treat the symptom of cardiopalmus, insomnia, unhappiness, depression and spontaneous perspiration, night sweat, cure rate is higher than 88%.
What comparative example 1 prepared calm the nerves resolving depression otherwise there is effect of hidroschesis, and cure rate only has 80%.
Above the embodiment of the present invention is described in detail, for one of ordinary skill in the art, according to the thought of the embodiment of the present invention, all will change in specific embodiments and applications, in sum, this description should not be construed as limitation of the present invention.
Claims (8)
1. to calm the nerves a resolving depression medicine, to it is characterized in that in mass parts containing following composition: 20 ~ 30 parts, Cinnabaris, Ganoderma 20 ~ 30 parts, Cortex Albiziae 15 ~ 25 parts, Os Draconis 15 ~ 25 parts, Ramulus Uncariae Cum Uncis 10 ~ 18 parts, Radix Ephedrae 8 ~ 15 parts, Fructus Tritici Levis 5 ~ 12 parts, Radix Rehmanniae 5 ~ 12 parts, Semen Coicis 2 ~ 8 parts, the Radix Angelicae Dahuricae 2 ~ 7 parts, Radix Cynanchi Atrati 1 ~ 5 part, Radix Scrophulariae 1 ~ 5 part, licopersicin 1 ~ 5 part.
2. one according to claim 1 is calmed the nerves resolving depression medicine, to it is characterized in that in mass parts containing following composition: 22 ~ 28 parts, Cinnabaris, Ganoderma 22 ~ 28 parts, Cortex Albiziae 18 ~ 23 parts, Os Draconis 16 ~ 22 parts, Ramulus Uncariae Cum Uncis 12 ~ 15 parts, Radix Ephedrae 9 ~ 14 parts, Fructus Tritici Levis 6 ~ 11 parts, Radix Rehmanniae 7 ~ 12 parts, Semen Coicis 3 ~ 7 parts, the Radix Angelicae Dahuricae 3 ~ 6 parts, Radix Cynanchi Atrati 2 ~ 4 parts, Radix Scrophulariae 2 ~ 4 parts, licopersicin 2 ~ 4 parts.
3. one according to claim 1 is calmed the nerves resolving depression medicine, to it is characterized in that in mass parts containing following composition: 24 parts, Cinnabaris, Ganoderma 24 parts, Cortex Albiziae 20 parts, Os Draconis 17 parts, Ramulus Uncariae Cum Uncis 13 parts, Radix Ephedrae 10 parts, Fructus Tritici Levis 7 parts, Radix Rehmanniae 8 parts, Semen Coicis 4 parts, the Radix Angelicae Dahuricae 4 parts, Radix Cynanchi Atrati 2.5 parts, Radix Scrophulariae 2.5 parts, licopersicin 2.5 parts.
4. one according to claim 1 is calmed the nerves resolving depression medicine, to it is characterized in that in mass parts containing following composition: 25 parts, Cinnabaris, Ganoderma 25 parts, Cortex Albiziae 21 parts, Os Draconis 19 parts, Ramulus Uncariae Cum Uncis 14 parts, Radix Ephedrae 12 parts, Fructus Tritici Levis 8.5 parts, Radix Rehmanniae 8.5 parts, Semen Coicis 5 parts, the Radix Angelicae Dahuricae 4.5 parts, Radix Cynanchi Atrati 3 parts, Radix Scrophulariae 3 parts, licopersicin 3 parts.
5. the preparation method of a kind of resolving depression medicine of calming the nerves as claimed in claim 1, is characterized in that the preparation process of the method is as follows:
The first step: Cinnabaris, Ganoderma, Cortex Albiziae, Os Draconis, Ramulus Uncariae Cum Uncis, Radix Ephedrae, Fructus Tritici Levis, Radix Rehmanniae, Semen Coicis, the Radix Angelicae Dahuricae, Radix Cynanchi Atrati, Radix Scrophulariae are cleaned up, fine powder is ground to form respectively after drying, fine powder is crossed 70 ~ 90 mesh sieves, then mix homogeneously, load tea bag;
Second step: by tea bag the 1st use 8 ~ 10 times of soak by water 4 ~ 6h, the 2nd, with 4 ~ 6 times of soak by water 2 ~ 3h, merges 2 decocting liquids, filters and obtains filtrate;
3rd step: add 80 ~ 90% ethanol with filtrate equivalent in filtrate, stirs, and leaves standstill 15-19h, gets supernatant, and after recovery ethanol, the relative density be evaporated to 50 ~ 60 DEG C time is the thick paste of 1.1;
4th step: by thick paste after licopersicin mix homogeneously, makes pill or ointment, is resolving depression medicine of calming the nerves.
6. the preparation method of a kind of resolving depression medicine of calming the nerves according to claim 5, is characterized in that: in the described first step, fine powder is crossed 80 mesh sieves.
7. the preparation method of a kind of resolving depression medicine of calming the nerves according to claim 5, is characterized in that: by tea bag the 1st use 9 times of soak by water 5h in described second step, and the 2nd with 5 times of soak by water 2.5h.
8. the preparation method of a kind of resolving depression medicine of calming the nerves according to claim 5, it is characterized in that: in filtrate, in the 3rd described step, add 85% ethanol with filtrate equivalent, stir, leave standstill 17h, get supernatant, after recovery ethanol, the relative density be evaporated to 55 DEG C time is the thick paste of 1.1.
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