CN105055749A - Traditional Chinese medicine composition for treating chronic cholecystitis with syndrome of hepatic stagnation and spleen deficiency - Google Patents
Traditional Chinese medicine composition for treating chronic cholecystitis with syndrome of hepatic stagnation and spleen deficiency Download PDFInfo
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Abstract
A traditional Chinese medicine composition for treating chronic cholecystitis with syndrome of hepatic stagnation and spleen deficiency is prepared from the following substances: amaranthus spinosus, swertia bimaculata, jasminum grandiflorum, paraboea crassifolia, juncus amplifolius, calystegia hederacea, ocimum basilicum, polypodiaceae drynaria quercifolia, asiatic bilberry leaves, radix cynanchi auriculati, cassia mimosoides, herba ecliptae, lungwortlike lobaria herb and sago palm starch. The traditional Chinese medicine composition can be used for treating chronic cholecystitis with syndrome of hepatic stagnation and spleen deficiency clinically.
Description
Technical field
The invention belongs to field of traditional Chinese medicine technology, particularly relate to a kind of Chinese medicine composition for the treatment of liver-depression and spleen-insufficiency type chronic cholecystitis.
Background technology
Chronic cholecystitis is the gallbladder chronic inflammatory disease because some factors such as calculus or proliferation of fibrous tissue cause.Belong to the category of the traditional Chinese medical science " hypochondriac pain ".Its pathogenic factor mainly contain following some: 1. feelings will is unsuccessful, depressed emotion or rage impairing the liver, QI stagnation of the liver and galibladder, and catharsis is unfavorable, vapour lock network numbness, and causes hypochondriac pain.2. eating and drinking without temperance, surfeit delicious food or eating and drinking too much at one meal, so that damp and hot heresy is pented up in liver and gall, liver and gall is lost in free flow of qi, and causes hypochondriac pain.Primary disease lacks classical symptom, can have upper right abdomen in various degree or middle epigastrium pain, companion's Nausea and vomiting, and general without heating and jaundice, some patients can have no symptom.At present, the method for the treatment of chronic cholecystitis mainly contains: Chinese traditional treatment, western medical treatment etc.Western medical treatment needs long-term taking Cholagogue drug, and can not fundamentally cure this disease, and Chinese traditional treatment is effective method, from the cause of disease, dialectical treatmert, fundamentally can cure chronic cholecystitis.The chronic cholecystitis that the traditional Chinese medical science causes according to different reason, carries out Coryza Treated by Syndrome Differentiation in conjunction with clinical practice, is divided into by primary disease: qi stagnation and blood stasis type, liver gallbladder damp-heat type, liver-depression and spleen-insufficiency type, deficiency and exhaustion of liver-YIN type.At present, the Chinese medicine for the treatment of chronic cholecystitis has a lot, but the Chinese medicine being aimed at liver-depression and spleen-insufficiency type chronic cholecystitis is actually rare, and there is the defects such as cure rate is low.
Summary of the invention
The object of the present invention is to provide that a kind of therapeutic effect is good, effective percentage is high, Chinese medicine composition to the treatment liver-depression and spleen-insufficiency type chronic cholecystitis of human non-toxic's side effect.
The object of the present invention is achieved like this, according to Chinese medical theory, utilize the property of medicine Cai le Amaranthus mangostanus L. of Chinese medicine uniqueness, Herba Swertiae bimaculatae, Flos jasmini, thick leaf Herba Boeae Hygrometricae, Juncus amplifolius A. Camus, Rhizoma Calystegiae Hederaceae (Herba Calystegiae Hederaceae), Herba Ocimi (Herba Ocimi Pilosi), Drynaria quercifolia (L.) J. Sm., Folium Vaccinii Bracteati, Radix Cynanchi Auriculati, the short top of ferrum arrow, Herba Ecliptae, Lobaria pulmonaria (L.) Hoffm., Amylum Metroxyli sagu, according to certain compatibility requirement, pass through and are processed into.
Prepare Chinese medicine composition of the present invention and make: le Amaranthus mangostanus L. 30-50 part, Herba Swertiae bimaculatae 30-50 part, Flos jasmini 20-40 part, thick leaf Herba Boeae Hygrometricae 20-40 part, Juncus amplifolius A. Camus 20-40 part, Rhizoma Calystegiae Hederaceae (Herba Calystegiae Hederaceae) 20-40 part, Herba Ocimi (Herba Ocimi Pilosi) 15-25 part, Drynaria quercifolia (L.) J. Sm. 15-25 part, Folium Vaccinii Bracteati 15-25 part, Radix Cynanchi Auriculati 15-25 part by following raw material medicaments, ferrum arrow short top 9-15 part, Herba Ecliptae 9-15 part, Lobaria pulmonaria (L.) Hoffm. 9-15 part, Amylum Metroxyli sagu 9-15 part.
Optimum weight part of traditional Chinese medicinal composition raw materials of the present invention is: le Amaranthus mangostanus L. 40 parts, Herba Swertiae bimaculatae 40 parts, Flos jasmini 30 parts, thick leaf Herba Boeae Hygrometricae 30 parts, Juncus amplifolius A. Camus 30 parts, Rhizoma Calystegiae Hederaceae (Herba Calystegiae Hederaceae) 30 parts, Herba Ocimi (Herba Ocimi Pilosi) 20 parts, Drynaria quercifolia (L.) J. Sm. 20 parts, Folium Vaccinii Bracteati 20 parts, Radix Cynanchi Auriculati 20 parts, the short top of ferrum arrow 12 parts, Herba Ecliptae 12 parts, Lobaria pulmonaria (L.) Hoffm. 12 parts, Amylum Metroxyli sagu 12 parts.
The pharmacological action of Chinese medicine of the present invention is as follows:
Le Amaranthus mangostanus L.: sweet, is slightly cold.Cooling blood for hemostasis, eliminating damp-heat, removing toxicity for eliminating carbuncles.Cure mainly gastrorrhagia, have blood in stool, hemorrhoidal bleeding, cholecystitis, cholelithiasis, dysentery, diarrhea due to damp-heat, leukorrhagia, difficulty and pain in micturition, laryngopharynx swelling and pain, eczema, carbuncle, gingiva is rotten to the corn, venom.
Herba Swertiae bimaculatae: bitter, acrid, cold.Heat-clearing and toxic substances removing, depressed liver-energy dispersing and function of gallbladder promoting.Cure mainly acute hepatitis, chronic hepatitis, cholecystitis, cold, fever, laryngopharynx swelling and pain, gingival swelling and pain, urinary tract infection, gastroenteritis, dysentery, acute catarrhal conjunctivitis, oral aphthae in children.
Flos jasmini: flat, nontoxic.Soothing liver-QI for relieving depression, promoting the circulation of QI to relieve pain.The side of body rib gastral cavity abdomen cured mainly caused by stagnation of QI due to depression of the liver is had a pain, and dysentery is suffered from abdominal pain.
Thick leaf Herba Boeae Hygrometricae: sweet is flat.Strengthening by means of tonics, hemostasis, cough-relieving.Cure mainly liver insufficiency of the spleen weak, over-strained hemoptysis, internal injury is spat blood, pneumonopathy cough with asthma, leucorrhea, the diseases such as innominate toxic swelling.
Juncus amplifolius A. Camus: pungent, micro-hardship is flat.Regulating QI to relieve pain, regulating menstruation and activating blood.Cure mainly stagnation of QI due to depression of the liver, pain in chest and hypochondrium, menoxenia, metrorrhagia leukorrhagia.
Rhizoma Calystegiae Hederaceae (Herba Calystegiae Hederaceae): sweet, micro-hardship is flat.Spleen invigorating, dampness removing, regulating menstruation.Cure mainly weakness of the spleen and stomach, dyspepsia, infantile milk regurgitation, infantile malnutrition, five types of stranguria, leukorrhagia, menoxenia.
Herba Ocimi (Herba Ocimi Pilosi): pungent, temperature.Invigorating the spleen for eliminating dampness, expelling wind and activating blood circulation.Cure mainly dampness taste, indigestion and loss of appetite stomachache, vomiting and diarrhoea, fever caused by exogenous pathogens, menoxenia, traumatic injury, skin eczema.
Drynaria quercifolia (L.) J. Sm.: bitter, temperature.Wind-damp dispelling, the kidney invigorating symplectic bone, promoting blood circulation and hemostasis.Cure mainly arthromyodynia with the passing of time, Liver and kidney two is empty, lumbocrural pain, the contracture of muscle arteries and veins, tinnitus due to deficiency of the kidney, toothache, frequent micturition, traumatic injury, fracture, traumatic hemorrhage.
Folium Vaccinii Bracteati: sour, puckery is flat.GUIXIN, spleen, kidney channel.Benefit the intestines and stomach, nourishing the liver and kidney.Cure mainly deficiency of spleen-QI and stomach-QI, chronic diarrhea, few food; Deficiency of the liver and kindey, waist knee joint is weak, early whitening of beard and hair.
Radix Cynanchi Auriculati: sweet, micro-hardship, flat.Return liver,kidney,spleen, stomach warp.Invigorating the liver and kidney, bone and muscle strengthening, benefiting essence-blood, strengthening the spleen to promote digestion, detoxification sore treatment.Cure mainly soreness of waist and knee joint, impotence and seminal emission, dizziness and tinnitus, early whitening of beard and hair, palpitation and insomnia, inappetence, infantile malnutrition, puerperal, milk was rare, sore, carbuncle and painful swelling, venom.
The short top of ferrum arrow: micro-hardship is flat.Relieving dyspepsia, invigorating spleen to remove dampness.Cure mainly dyspepsia not disappear, infantile malnutrition, have loose bowels, edema, beriberi distension.
Herba Ecliptae: sweet, sour, cool.Return liver, kidney channel.Liver and kidney tonifying, cooling blood for hemostasis.Cure mainly deficiency of the liver and kindey, have a dizzy spell, early whitening of beard and hair, spit blood, spitting of blood, epistaxis, has blood in stool, dysentery, metrorrhagia, traumatic hemorrhage.
Lobaria pulmonaria (L.) Hoffm.: light, micro-hardship is flat.Return spleen, kidney channel.Spleen invigorating, diuretic, dispels the wind, antipruritic, antiinflammatory.Cure mainly dyspepsia, infantile malnutrition, ascariasis, abdominal distention, oedema due to nephritis, burn and scald, skin pruritus, innominate toxic swelling.
Amylum Metroxyli sagu: sweet, temperature.Warming middle-JIAO and strengthening the spleen.Control weakness of the spleen and stomach, dyspepsia.
The traditional Chinese medical science is thought, liver-depression and spleen-insufficiency type chronic cholecystitis many because of feelings will unsuccessful, depressed emotion or rage impairing the liver, QI stagnation of the liver and galibladder, catharsis is unfavorable, vapour lock network numbness, and causes hypochondriac pain; In addition surfeit delicious food or eating and drinking too much at one meal, thus damp and hot heresy is pented up in liver and gall, liver and gall is lost in free flow of qi, and causes hypochondriac pain.The cooling blood for hemostasis of le Amaranthus mangostanus L., clearing away heat-damp and promoting diuresis, removing toxicity for eliminating carbuncles in Ben Faming, Herba Swertiae bimaculatae heat-clearing and toxic substances removing, depressed liver-energy dispersing and function of gallbladder promoting are monarch drug; Flos jasmini soothing liver-QI for relieving depression, promoting the circulation of QI to relieve pain, thick leaf Herba Boeae Hygrometricae strengthening by means of tonics, hemostasis, cough-relieving, Juncus amplifolius A. Camus regulating QI to relieve pain, regulating menstruation and activating blood, Rhizoma Calystegiae Hederaceae (Herba Calystegiae Hederaceae) spleen invigorating, dampness removing, regulating menstruation are ministerial drug; Herba Ocimi (Herba Ocimi Pilosi) invigorating the spleen for eliminating dampness, expelling wind and activating blood circulation, Drynaria quercifolia (L.) J. Sm. wind-damp dispelling, the kidney invigorating symplectic bone, promoting blood circulation and hemostasis, Folium Vaccinii Bracteati benefit the intestines and stomach, nourishing the liver and kidney, Radix Cynanchi Auriculati invigorating the liver and kidney, bone and muscle strengthening, benefiting essence-blood, strengthening the spleen to promote digestion, detoxification sore treatment, the short top relieving dyspepsia of ferrum arrow, invigorating spleen to remove dampness, Herba Ecliptae liver and kidney tonifying, cooling blood for hemostasis, Lobaria pulmonaria (L.) Hoffm. spleen invigorating, diuretic, dispel the wind, antipruritic, antiinflammatory, Amylum Metroxyli sagu warming middle-JIAO and strengthening the spleen.Find through clinical practice, to liver-depression and spleen-insufficiency type chronic cholecystitis, there is unique curative effect, effect of cooling blood for hemostasis, clearing away heat-damp and promoting diuresis, depressed liver-energy dispersing and function of gallbladder promoting, soothing liver-QI for relieving depression, promoting the circulation of QI to relieve pain, strengthening the spleen to promote digestion, liver and kidney tonifying, relieving dyspepsia, warming middle-JIAO and strengthening the spleen, heat-clearing and toxic substances removing played altogether by all medicines, reaches the object for the treatment of liver-depression and spleen-insufficiency type chronic cholecystitis.
Chinese medicine composition of the present invention was in 2007 to 2012 the routine patients of clinical observation liver-depression and spleen-insufficiency type chronic cholecystitis 128, and clinical report is as follows:
1, physical data
In 128 routine patients, in age 18-65 year, the course of disease is many at 3 months to 8 years, 47.5 years old mean age.
2, diagnostic criteria
" Chinese medical disease Standardization of diagnosis and curative effect " that 2.1 diagnosis basis State Administration of Traditional Chinese Medicines issue:
persistence upper right abdomen dull pain or sense of discomfort, or Ban You omoplate district pain;
there are the indigestion symptoms such as nauseating, belch, acid regurgitation, abdominal distention and scorching hot, the postemphasis of feed greasy food;
the course of disease is long, and the state of an illness has acute attack and alleviates feature alternately;
gallbladder area is carved with mild tenderness and is kowtowed pain;
in bile, mucus increases, and leukocyte is in heaps, positive bacterial culture;
the visible cholelithiasis of ultrasound diagnosis, thickening of capsule wall of gallbladder, gallbladder reduces or is out of shape;
the visible cholelithiasis of cholecystography, gallbladder reduces or is out of shape, and gallbladder contraction function is bad, or gallbladder development is thin.
Clinical symptoms: side of body rib dull pain, dysphoria with feverish sensation in the chest palms and soles, hunger but having no desire to eat, thirst but no desire to drink, body of the tongue extra dry red wine no fur, thready and rapid pulse, double stagnation of liver-QI is then sighed, and holding under the arm damp and hotly has greasy coating, and blood stasis is shown in purple tongue.
2.2 exclusion standards:
age is under-18s or over-65s person;
the suppurative cholecystitis of acute gangrenous cholecystitis, acute obstruction, perforation of gallbladder peritonitis person;
gestation or women breast-feeding their children, be associated with severe primary disease, the psychotics such as cardiovascular, liver, kidney and hemopoietic system.
3, Therapeutic Method:
3.1 prescription: le Amaranthus mangostanus L. 40g, Herba Swertiae bimaculatae 40g, Flos jasmini 30g, thick leaf Herba Boeae Hygrometricae 30g, Juncus amplifolius A. Camus 30g, Rhizoma Calystegiae Hederaceae (Herba Calystegiae Hederaceae) 30g, Herba Ocimi (Herba Ocimi Pilosi) 20g, Drynaria quercifolia (L.) J. Sm. 20g, Folium Vaccinii Bracteati 20g, Radix Cynanchi Auriculati 20g, the short top 12g of ferrum arrow, Herba Ecliptae 12g, Lobaria pulmonaria (L.) Hoffm. 12g, Amylum Metroxyli sagu 12g.
3.2 methods of preparation and use: said medicine routinely technique makes decoction, every day 1 dose, every day 2 times 15 days was 1 course for the treatment of.
4, therapeutic outcome:
4.1 specify with reference to " Chinese medicine Clinical Researches of New Drugs guideline ":
Cure: the primary and secondary transference cure of this syndrome, ultrasound diagnosis gallbladder wall and contractile function recover normal, and gallbladder district pain disappears, and diet, digestion recover normal, and drug withdrawal 3 months is unchanged, follows up a case by regular visits to half a year more than without recurrence;
Take a turn for the better: the primary and secondary symptom improvement of this syndrome accounts for more than half, and ultrasound diagnosis gallbladder wall and contractile function have clear improvement, and gallbladder district pain is clearly better, and diet, digestion are clearly better;
Invalid: through treatment symptom without alleviation, ultrasound diagnosis gallbladder wall and contractile function are without significant change, and every symptom is not improved.
4.2 results: in 128 routine patients, cure 112 examples (87.5%), 10 examples that take a turn for the better (7.8%), and invalid 6 examples (4.7%), total effective rate is 95.3%.
5, model case
5.1 business, man, 49 years old.Patient once arrived certain hospital therapy because of upper right abdominal distention and pain, was diagnosed as acute cholecystitis, gave intravenous drip levofloxacin, remission.After this often because there is right Upper abdominal pain when the greasy or feelings will of taking food is not relaxed, and to lower back radiation, companion's Nausea and vomiting, reaches 2 years.Because there is upper right abdomen dull pain, abdominal distention, singultus after feed Carnis Sus domestica, vomiting.The light tenderness of upper right abdomen, does not touch gallbladder, Murphy's sign (+).Glutinous greasy dull in mouthful, inappetence, appetite reduces, urine xanthochromia, constipation.Ultrasound diagnosis: gallbladder wall hair, to thicken.Be diagnosed as liver-depression and spleen-insufficiency type chronic cholecystitis.Take medicine of the present invention, treat 2 courses for the treatment of, symptom obviously alleviates, and continues to take 3 courses for the treatment of, and symptom and sign disappears, and B ultrasonic is checked: gallbladder volume is normal, and wall is smooth, and recovery from illness is followed up a case by regular visits to after 1 year without recurrence.
5.2 peaceful certain, man, 38 years old.Patient closely hinders in food and drink, side of body rib dull pain, dysphoria with feverish sensation in the chest palms and soles, hunger but having no desire to eat, thirst but no desire to drink, body of the tongue extra dry red wine no fur, thready and rapid pulse.Ultrasound diagnosis: cyst wall edema, volume increases, and gallbladder wall is rough and coarse.Be diagnosed as liver-depression and spleen-insufficiency type chronic cholecystitis.Take medicine of the present invention, every day 1 dose, after 2 courses for the treatment of, B ultrasonic is checked: gallbladder clear-cut, smooth, and size and form is normal, continues to take 2 courses for the treatment of, recovery from illness, follows up a case by regular visits to after 1 year without recurrence.
5.3 Dong, female, 43 years old.Patient has chronic cholecystitis history more than 10 year, and outbreak when Chang Yu suffers from cold, tired, mind is not good, within the next few days because overworking and occurring coercing rib dull pain, shoulder and back ache, dysphoria with feverish sensation in the chest palms and soles, uneasy sleeping at night, hunger but having no desire to eat, xerostomia is drunk less, soreness of the waist and knees, the red no fur of tongue light, thready and rapid pulse.Ultrasound diagnosis: gallbladder 7.1cm*3.9cm, wall thickness 0.5cm is fuzzy in capsule.Be diagnosed as liver-depression and spleen-insufficiency type chronic cholecystitis.Take medicine of the present invention, every day 1 dose, after 2 courses for the treatment of, symptom is clearly better, and continues to take 3 courses for the treatment of, and through B ultrasonic check, gallbladder clear-cut, smooth, size and form are normal, and recovery from illness is followed up a case by regular visits to after 1 year without recurrence.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is further illustrated, and this embodiment following does not only limit the present invention for illustration of the present invention.
Embodiment 1, treat the Chinese medicine composition Shi You le Amaranthus mangostanus L. 30g of liver-depression and spleen-insufficiency type chronic cholecystitis, Herba Swertiae bimaculatae 30g, Flos jasmini 20g, thick leaf Herba Boeae Hygrometricae 20g, Juncus amplifolius A. Camus 20g, Rhizoma Calystegiae Hederaceae (Herba Calystegiae Hederaceae) 20g, Herba Ocimi (Herba Ocimi Pilosi) 15g, Drynaria quercifolia (L.) J. Sm. 15g, Folium Vaccinii Bracteati 15g, a Radix Cynanchi Auriculati 15g, the short top 9g of ferrum arrow, Herba Ecliptae 9g, Lobaria pulmonaria (L.) Hoffm. 9g, Amylum Metroxyli sagu 9g make.
Embodiment 2, treat the Chinese medicine composition Shi You le Amaranthus mangostanus L. 40g of liver-depression and spleen-insufficiency type chronic cholecystitis, Herba Swertiae bimaculatae 40g, Flos jasmini 30g, thick leaf Herba Boeae Hygrometricae 30g, Juncus amplifolius A. Camus 30g, Rhizoma Calystegiae Hederaceae (Herba Calystegiae Hederaceae) 30g, Herba Ocimi (Herba Ocimi Pilosi) 20g, Drynaria quercifolia (L.) J. Sm. 20g, Folium Vaccinii Bracteati 20g, a Radix Cynanchi Auriculati 20g, the short top 12g of ferrum arrow, Herba Ecliptae 12g, Lobaria pulmonaria (L.) Hoffm. 12g, Amylum Metroxyli sagu 12g make.
Embodiment 3, treat the Chinese medicine composition Shi You le Amaranthus mangostanus L. 50g of liver-depression and spleen-insufficiency type chronic cholecystitis, Herba Swertiae bimaculatae 50g, Flos jasmini 40g, thick leaf Herba Boeae Hygrometricae 40g, Juncus amplifolius A. Camus 40g, Rhizoma Calystegiae Hederaceae (Herba Calystegiae Hederaceae) 40g, Herba Ocimi (Herba Ocimi Pilosi) 25g, Drynaria quercifolia (L.) J. Sm. 25g, Folium Vaccinii Bracteati 25g, a Radix Cynanchi Auriculati 25g, the short top 15g of ferrum arrow, Herba Ecliptae 15g, Lobaria pulmonaria (L.) Hoffm. 15g, Amylum Metroxyli sagu 15g make.
Claims (2)
1. treat the Chinese medicine composition of liver-depression and spleen-insufficiency type chronic cholecystitis for one kind, it is characterized in that, it makes: le Amaranthus mangostanus L. 30-50 part, Herba Swertiae bimaculatae 30-50 part, Flos jasmini 20-40 part, thick leaf Herba Boeae Hygrometricae 20-40 part, Juncus amplifolius A. Camus 20-40 part, Rhizoma Calystegiae Hederaceae (Herba Calystegiae Hederaceae) 20-40 part, Herba Ocimi (Herba Ocimi Pilosi) 15-25 part, Drynaria quercifolia (L.) J. Sm. 15-25 part, Folium Vaccinii Bracteati 15-25 part, Radix Cynanchi Auriculati 15-25 part, ferrum arrow short top 9-15 part, Herba Ecliptae 9-15 part, Lobaria pulmonaria (L.) Hoffm. 9-15 part, Amylum Metroxyli sagu 9-15 part by following raw material medicaments.
2. Chinese medicine composition according to claim 1, it is characterized in that, it makes: le Amaranthus mangostanus L. 40 parts, Herba Swertiae bimaculatae 40 parts, Flos jasmini 30 parts, thick leaf Herba Boeae Hygrometricae 30 parts, Juncus amplifolius A. Camus 30 parts, Rhizoma Calystegiae Hederaceae (Herba Calystegiae Hederaceae) 30 parts, Herba Ocimi (Herba Ocimi Pilosi) 20 parts, Drynaria quercifolia (L.) J. Sm. 20 parts, Folium Vaccinii Bracteati 20 parts, Radix Cynanchi Auriculati 20 parts by following raw material medicaments, the short top of ferrum arrow 12 parts, Herba Ecliptae 12 parts, Lobaria pulmonaria (L.) Hoffm. 12 parts, Amylum Metroxyli sagu 12 parts.
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Application publication date: 20151118 |