CN104027631A

CN104027631A - Traditional Chinese medicine preparation for treating liver depression and phlegm stagnation type cholecystitis

Info

Publication number: CN104027631A
Application number: CN201410221487.6A
Authority: CN
Inventors: 陈国明
Original assignee: Individual
Current assignee: Individual
Priority date: 2014-05-19
Filing date: 2014-05-19
Publication date: 2014-09-10

Abstract

The invention provides a traditional Chinese medicine preparation for treating liver depression and phlegm stagnation type cholecystitis. The traditional Chinese medicine preparation is prepared from radix bupleuri, caulis bambusae in taeniam, pericarpium citri reticulatae, ligusticum wallichii, loosestrife, loofah sponge, rhizoma cyperi and madder. The traditional Chinese medicine preparation can be clinically used for treating liver depression and phlegm stagnation type cholecystitis.

Description

A kind of Chinese drugs agentia for the treatment of stagnation of liver-QI expectorant stasis of blood type cholecystitis

Technical field

The invention belongs to technical field of Chinese medicines, especially relate to a kind of Chinese drugs agentia for the treatment of stagnation of liver-QI expectorant stasis of blood type cholecystitis.

Background technology

That chronic cholecystitis refers to is that gallbladder continues, the inflammatory process of outbreak repeatedly, and clinical manifestation is right Upper abdominal pain, or accompanies right shoulder back radiating pain, can accompany the indigestion symptoms such as nauseating, vomiting, belch, acid regurgitation, anorexia be greasy.Draw through inventor's long-term practice, Chinese medicine treating the liver stagnated phlegm stasis of blood type cholecystitis has better effect, obtains good effect.

Summary of the invention

The object of the present invention is to provide the Chinese drugs agentia of the treatment stagnation of liver-QI expectorant stasis of blood type cholecystitis that a kind of therapeutic effect is good, effective percentage is high, human body is had no side effect.

The present invention, according to Chinese medical theory, adopts Radix Bupleuri, Caulis Bambusae In Taenia, Pericarpium Citri Reticulatae, Rhizoma Chuanxiong, Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis), Retinervus Luffae Fructus, Rhizoma Cyperi, Radix Rubiae according to certain compatibility requirement, through being processed into.

Preparing Chinese drugs agentia of the present invention is made up of following raw material medicaments: Radix Bupleuri 20-40 part, Caulis Bambusae In Taenia 20-40 part, Pericarpium Citri Reticulatae 15-25 part, Rhizoma Chuanxiong 15-25 part, Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis) 15-25 part, Retinervus Luffae Fructus 15-25 part, Rhizoma Cyperi 10-20 part, Radix Rubiae 10-20 part.

Optimum weight part of Chinese drugs agentia crude drug of the present invention is: 30 parts of Radix Bupleuri, 30 parts of Caulis Bambusae In Taenia, 20 parts of Pericarpium Citri Reticulataes, 20 parts of Rhizoma Chuanxiongs, 20 parts of Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis), 20 parts of Retinervus Luffae Fructuss, 15 parts of Rhizoma Cyperis, 15 parts, Radix Rubiae.

The pharmacological action of Chinese medicine of the present invention is as follows:

Radix Bupleuri: bitter, pungent, be slightly cold, return liver, gallbladder meridian.Evacuation is brought down a fever, dispersing the stagnated live-QI to relieve the stagnation of QI.For stagnation of QI due to depression of the liver, pain in chest and hypochondrium.

Caulis Bambusae In Taenia: sweet, be slightly cold, attach to the lung and stomach meridians.Removing heat-phlegm, relieves restlessness and prevents vomiting.For cough or dysphoria and insomnia due to expectorant heat, gastropyretic vomiting etc.

Pericarpium Citri Reticulatae: acrid, bitter, warm, return spleen, stomach, lung meridian.Regulate the flow of vital energy in tune, stopping nausea and vomiting by lowering the adverse flow of QI, drying dampness to eliminate phlegm.Full vexed for chest and diaphragm, abdominal distention, anorexia, vomiting etc.

Rhizoma Chuanxiong: pungent, warm, return liver, gallbladder, heart channel.Blood-activating and qi-promoting, wind-expelling pain-stopping.For stagnation of QI and blood, rheumatic arthralgia.

Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis): bitter, pungent, flat.Return liver, spleen channel.Clearing away heat-damp and promoting diuresis, promoting blood circulation to remove blood stasis, removing toxicity for eliminating carbuncles.For edema, pyretic stranguria, jaundice, dysentery, rheumatism pyretic arthralgia, leukorrhagia, amenorrhea, traumatic injury, fracture, traumatic hemorrhage, acute mastitis, furuncle, the diseases such as venom.

Retinervus Luffae Fructus: sweet, flat.Return lung, stomach, Liver Channel.Dispelling wind and removing obstruction in the collateral, removing toxic substances is reduced phlegm.For rheumatic arthralgia, the thoracic obstruction, chest and hypochondrium etc.Rhizoma Cyperi: pungent, sweet, micro-hardship, flat.Return liver, tri-jiao channel.Regulate the flow of vital energy resolving depression, regulating menstruation, antiabortive.For distending pain over the hypochondrium, gastral cavity abdomen feeling of fullness pain, abdominal pain during menstruation etc.

Radix Rubiae: bitter, cold.GUIXIN, Liver Channel.Cooling blood for hemostasis, blood circulation promoting and blood stasis dispelling.Clinical in heat in blood spitting of blood, haematemesis, epistaxis, hematuria, has blood in stool, metrorrhagia, amenorrhea, postpartum stagnation stomachache, traumatic injury, rheumatic arthralgia, jaundice, carbuncle sore, hemorrhoid swell and wait disease.

Chinese drugs agentia of the present invention was in 2008 to 2012 clinical observation stagnation of liver-QI expectorant stasis of blood type cholecystitis 69 routine patients, and clinical report is as follows:

1, physical data

In 69 routine patients, age 17-68 year, the course of disease is many at 2 months to 5 years, 46.8 years old mean age.

2, diagnostic criteria

" traditional Chinese medical science disease Standardization of diagnosis and curative effect " that diagnosis basis State Administration of Traditional Chinese Medicine issues:

1. persistence upper right abdomen dull pain or sense of discomfort, or Ban You omoplate district pain; 2. there are the indigestion symptoms such as nauseating, belch, acid regurgitation, abdominal distention and scorching hot, the postemphasis of feed greasy food; 3. the course of disease is long, and the state of an illness has acute attack and alleviates feature alternately; 4. gallbladder area is carved with mild tenderness and is kowtowed pain; 5. in bile, mucus increases, and leukocyte is in heaps, positive bacterial culture; 6. the visible cholelithiasis of ultrasound diagnosis, thickening of capsule wall of gallbladder, gallbladder dwindles or is out of shape; 7. the visible cholelithiasis of cholecystography, gallbladder dwindles or is out of shape, and gallbladder contraction function is bad, or gallbladder develops thin.

Clinical symptoms: it is indefinite that hypochondriac pain is indistinctly walked to alter, connects and also pain of shoulder back, and hypochondriac pain is fixing at nightfall does not move, and happiness is sighed, and personality is suspicious, woman's menoxenia, and xerostomia hardship, purplish tongue gas, stringy and thready pulse, above symptom increases and decreases with feelings will quality.

3, Therapeutic Method

3.1 prescriptions: Radix Bupleuri 30g, Caulis Bambusae In Taenia 30g, Pericarpium Citri Reticulatae 20g, Rhizoma Chuanxiong 20g, Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis) 20g, Retinervus Luffae Fructus 20g, Rhizoma Cyperi 15g, Radix Rubiae 15g.

3.2 methods of preparation and use: said medicine routinely technique is made decoction, every day 2 times, 10 days were 1 course for the treatment of at 1 dose of oral every day.

4, therapeutic outcome:

4.1 formulate with reference to " Chinese medicine Clinical Researches of New Drugs guideline ":

Recovery from illness: the primary and secondary syndrome of this syndrome disappears, it is normal that ultrasound diagnosis gallbladder wall and contractile function recover, and gallbladder district pain disappears, and diet, digestion recover normal.Drug withdrawal 3 months is unchanged, follows up a case by regular visits to half a year above without recurrence;

Take a turn for the better: this syndrome primary and secondary syndrome improvement accounts for more than half, and ultrasound diagnosis gallbladder wall and contractile function have clear improvement, and gallbladder district tenderness is clearly better, and diet, digestion are clearly better;

Invalid: through treatment symptom, without alleviation, ultrasound diagnosis gallbladder wall and contractile function are without significant change, and every symptom is not improved.4.2 results: in 69 routine patients, recovery from illness 35 examples (50.7%), 26 examples that take a turn for the better (37.7%), invalid 8 examples (11.6%), total effective rate is 88.4%.

5. model case

5.1 bent certain, female, 39 years old, suffer from cholecystitis 3 years, when pain to the radiation of shoulder back, delayed menstrual cycle, inappetence, appetite reduces, body of the tongue has purple gas, thin lingual fur is slightly yellow greasy, stringy and thready pulse, above symptom increases and decreases with feelings will quality.Take medicine of the present invention, 1 dose of every day, after 2 courses for the treatment of, symptom is clearly better, and continues to take 3 courses for the treatment of, through B ultrasonic check, and gallbladder clear-cut, smooth, size and form is normal, and recovery from illness is followed up a case by regular visits to after 1 year without recurrence.

5.2 Qiu, man, 53 years old.Because upper right abdominal distention and pain once arrived certain hospital therapy, be diagnosed as acute cholecystitis, give intravenous drip levofloxacin, remission.After this often occur right Upper abdominal pain while not relaxing because of the greasy or feelings will of taking food, and to lower back radiation, companion feels sick, vomiting, reaches 2 years.Because occurring upper right abdomen dull pain after feed Carnis Sus domestica, abdominal distention, singultus, vomiting.The light tenderness of upper right abdomen, does not touch gallbladder, Murphy's sign (+).Take medicine of the present invention, treat 2 courses for the treatment of, symptom obviously alleviates, and continues to take 3 courses for the treatment of, and symptom and sign disappears, B ultrasonic check: gallbladder normal in size, wall is smooth, does not visit and stone-echo recovery from illness in capsule, follows up a case by regular visits to without recurrence after half a year.

5.3 grandsons, man, 40 years old.Suffer from cholecystitis 2 years.When medical, hypochondriac pain is indistinctly walked to alter indefinite, connects and also pain of shoulder back, and hypochondriac pain is fixing at nightfall does not move, xerostomia hardship, purplish tongue gas, stringy and thready pulse.Ultrasound diagnosis, cyst wall thickens, and volume increases, and gallbladder wall is rough and coarse.Take medicine of the present invention, treat 2 courses for the treatment of, symptom obviously alleviates, through B ultrasonic check, and gallbladder clear-cut, smooth, size and form normal, continues to take 2 courses for the treatment of, and recovery from illness is followed up a case by regular visits to after half a year without recurrence.

Detailed description of the invention

Embodiment 1, a kind of Chinese drugs agentia for the treatment of stagnation of liver-QI expectorant stasis of blood type cholecystitis, is to be made up of Radix Bupleuri 20g, Caulis Bambusae In Taenia 20g, Pericarpium Citri Reticulatae 15g, Rhizoma Chuanxiong 15g, Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis) 15g, Retinervus Luffae Fructus 15g, Rhizoma Cyperi 10g, Radix Rubiae 10g.

Embodiment 2, a kind of Chinese drugs agentia for the treatment of stagnation of liver-QI expectorant stasis of blood type cholecystitis, is to be made up of Radix Bupleuri 30g, Caulis Bambusae In Taenia 30g, Pericarpium Citri Reticulatae 20g, Rhizoma Chuanxiong 20g, Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis) 20g, Retinervus Luffae Fructus 20g, Rhizoma Cyperi 15g, Radix Rubiae 15g.

Embodiment 3, a kind of Chinese drugs agentia for the treatment of stagnation of liver-QI expectorant stasis of blood type cholecystitis, is to be made up of Radix Bupleuri 40g, Caulis Bambusae In Taenia 40g, Pericarpium Citri Reticulatae 25g, Rhizoma Chuanxiong 25g, Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis) 25g, Retinervus Luffae Fructus 25g, Rhizoma Cyperi 20g, Radix Rubiae 20g.

Claims

1. treat a Chinese drugs agentia for stagnation of liver-QI expectorant stasis of blood type cholecystitis, it is characterized in that it is to be made up of following raw material medicaments:

Radix Bupleuri 20-40 part, Caulis Bambusae In Taenia 20-40 part, Pericarpium Citri Reticulatae 15-25 part, Rhizoma Chuanxiong 15-25 part, Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis) 15-25 part, Retinervus Luffae Fructus 15-25 part, Rhizoma Cyperi 10-20 part, Radix Rubiae 10-20 part.

2. Chinese drugs agentia according to claim 1, is characterized in that it is to be made up of following raw material medicaments:

30 parts of Radix Bupleuri, 30 parts of Caulis Bambusae In Taenia, 20 parts of Pericarpium Citri Reticulataes, 20 parts of Rhizoma Chuanxiongs, 20 parts of Herba Lysimachiae Clethroids (Radix Seu Herba Lysimachiae Clethroidis), 20 parts of Retinervus Luffae Fructuss, 15 parts of Rhizoma Cyperis, 15 parts, Radix Rubiae.