CN103536790A - Traditional Chinese medicine for treating acute icteric hepatitis - Google Patents

Abstract

The invention discloses a traditional Chinese medicine for treating acute icteric hepatitis. The traditional Chinese medicine is prepared from oriental wormwood, lalang grass rhizome, honeysuckle, fructus forsythiae, ramulus acaciae, pigeonpea, root bark of the peony tree, rhizoma menispermi, white atractylodes rhizome, radix bupleuri and liquorice. The traditional Chinese medicine can be applied to treatment of the acute icteric hepatitis in clinical.

Description

A kind of Chinese medicine for the treatment of acute icterohepatitis

Technical field

The invention belongs to technical field of Chinese medicines, especially relate to a kind of Chinese medicine for the treatment of acute icterohepatitis.

Background technology

Acute icterohepatitis is one of common clinically infectious disease of the digestive tract.Clinical manifestation is that onset urgency, loss of appetite, epigastric discomfort, hepatic region have tenderness and percussion pain.The treatment of acute icterohepatitis does not have specific medicine, emphasizes nutritional support and early stage strictly lying up, and to symptom, goes down and can increase gradually activity, is aided with suitable medicine.Through inventor's long-term practice, draw, Chinese medicine is controlled acute icterohepatitis and is had better effect, obtains good effect.

Summary of the invention

The object of the present invention is to provide the Chinese medicine of the treatment acute icterohepatitis that a kind of therapeutic effect is good, effective percentage is high, human body is had no side effect.

The present invention, according to Chinese medical theory, utilizes the property of medicine of Chinese medicine uniqueness, adopts Herba Artemisiae Scopariae, Rhizoma Imperatae, Flos Lonicerae, Fructus Forsythiae, Catechu, Semen Cajani, Cortex Moutan, Rhizoma Menispermi, the Rhizoma Atractylodis Macrocephalae, Radix Bupleuri, Radix Glycyrrhizae according to certain compatibility requirement, through being processed into.

Preparing Chinese medicine of the present invention is made by following raw material medicaments: Herba Artemisiae Scopariae 20-40 part, Rhizoma Imperatae 20-40 part, Flos Lonicerae 20-40 part, Fructus Forsythiae 20-40 part, Catechu 15-25 part, Semen Cajani 15-25 part, Cortex Moutan 15-25 part, Rhizoma Menispermi 15-25 part, Rhizoma Atractylodis Macrocephalae 8-15 part, Radix Bupleuri 8-15 part, Radix Glycyrrhizae 8-15 part.

Optimum weight part of raw material of Chinese medicine medicine of the present invention is: 30 parts of Herba Artemisiae Scopariaes, 30 parts of Rhizoma Imperataes, 30 parts of Flos Loniceraes, 30 parts of Fructus Forsythiaes, 20 parts of Catechu, 20 parts of Semen Cajanis, 20 parts of Cortex Moutans, 20 parts of Rhizoma Menispermis, 10 parts of the Rhizoma Atractylodis Macrocephalaes, 10 parts of Radix Bupleuri, 10 parts, Radix Glycyrrhizae.

The pharmacological action of Chinese medicine of the present invention is as follows:

Herba Artemisiae Scopariae: bitter, pungent, be slightly cold.Return spleen, stomach, liver, gallbladder meridian.Clearing away damp-heat, jaundice eliminating subcutaneous ulcer.For jaundice oliguria, eczema pruritus; Infectious jaundice type hepatitis.

Rhizoma Imperatae: sweet, cold.Return stomach, lung, the heart, urinary bladder channel.Cooling blood for hemostasis, clearing away heat and promoting production of body fluid, inducing diuresis for treating stranguria syndrome.Clinical in jaundice, heat in blood is hemorrhage, calentura excessive thirst, gastric heat vomiting, dyspnea and cough due to lung-heat, the puckery pain of dribbling urination, the diseases such as edema.

Flos Lonicerae: sweet, cold, return lung, the heart, stomach warp.Heat-clearing and toxic substances removing, dispelling wind and heat pathogens.For carbuncle furuncle, toxic-heat and blood stasis.

Fructus Forsythiae: bitter, be slightly cold, return lung, the heart, gallbladder meridian.Heat-clearing and toxic substances removing, eliminating carbuncle eliminating stagnation.For carbuncle sore tumefacting virus, scrofula sucutaneous nodule.

Catechu: bitter, cool.GUIXIN, lung meridian.Removing dampness sore, hemostasis analgesic therapy, removing heat-phlegm.For skin infection, burst and do not hold back for a long time, eczema flowing water, aphtha, spitting of blood, spits blood, and hematuria, has blood in stool, metrorrhagia, traumatic hemorrhage, hemorrhoid carbuncle, the diseases such as phlegm-heat cough.

Semen Cajani: pungent, puckery, flat.Return liver, spleen channel.Dampness removing, detumescence, dissipating blood stasis, hemostasis.For rheumatic arthralgia, traumatic injury, epistaxis, has blood in stool, furuncle toxic swelling, prolonged lochia, edema, icterohepatitis etc.

Cortex Moutan: arduous, cool, be slightly cold.GUIXIN, sweet, kidney, lung meridian.Heat clearing away, promoting blood circulation to remove blood stasis.For the epidemic febrile disease pathogenic heat attacking blood system in febrile diseases, tell nosebleed, deficiency of YIN osteopyrexia and fever, amenorrhea due to stagnation of blood, dysmenorrhea, carbuncle sore tumefacting virus, falls and flutters the pain of injury, rheumatism pyretic arthralgia etc.

Rhizoma Menispermi: bitter, cold, slightly poisonous.Return lung, stomach, large intestine channel.Heat-clearing and toxic substances removing, reducing swelling and alleviating pain, dampness removing.For laryngopharynx swelling and pain, cough due to lung-heat, mumps, dysentery, jaundice, rheumatic arthralgia, swelling and pain of hemorrhoid, snake bite and insect sting etc.

The Rhizoma Atractylodis Macrocephalae: bitter, sweet, warm.Return spleen, stomach warp.Air making-up and spleen enlivening, dampness diuretic, hidroschesis, antiabortive.For deficiency of spleen-QI and stomach-QI, transporting is unable, anorexia and loose stool, and distension and fullness in the abdomen, insufficiency of the spleen water retention, and be phlegm retention, edema, dysuria, frequent fetal movement etc.

Radix Bupleuri: bitter, pungent, be slightly cold, return liver, gallbladder meridian.Evacuation is brought down a fever, dispersing the stagnated live-QI to relieve the stagnation of QI.For stagnation of QI due to depression of the liver, pain in chest and hypochondrium.

Radix Glycyrrhizae: sweet, flat, GUIXIN, lung, spleen, stomach warp.QI invigorating invigorating middle warmer, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, the mediation property of medicine.For severe palpitation, the irregularly intermittent and regularly intermittent pulse of deficiency of heart-QI, pathopyretic ulcer, laryngopharynx swelling and pain.

Chinese medicine of the present invention was in 2006 to 2011 the routine patients of clinical observation acute icterohepatitis 95, and clinical report is as follows:

1, physical data

In 95 routine patients, age 17-62 year, 5 days average times of morbidity, 44.3 years old mean age.

2, diagnostic criteria

It is the diagnostic criteria of this programme that the < < new Chinese medicine guideline of clinical investigations > > that Ministry of Health of the People's Republic of China formulates (1993 first volume) is take in diagnostic criteria, and its particular content is as follows:

1) Chinese medical discrimination

Yellow skin and eye, yellow distinct, generate heat thirsty, abdominal part distension, xerostomia and hardship is indigestion and loss of appetite, nausea and vomiting, oliguria, constipation, yellowish fur pulse condition stringy and rapid pulse.

Main symptom: (1) yellow skin and eye, yellow distinct, generate heat thirsty; (2) indigestion and loss of appetite; (3) nausea and vomiting; (4) yellow and greasy fur; (5) wiry and frequent pulse.Inferior card: (1) xerostomia and hardship; (2) abdominal part distension; (3) oliguria with reddish urine; (4) constipation.

All possess any one in main symptom (1) and (2), (3), (4), (5), or in main symptom and inferior card, any binomial all can belong to assertive evidence.

2) Western medicine diagnose standard

(1) Clinical typing diagnostic criteria

Acute icterohepatitis: all acute onsets, the hepatitis symptom, sign and the chemical examination that have are in various degree abnormal, and serum total bilirubin (SB) is more than 17.1 μ mol/L, and urine bilirubin is positive, and get rid of the jaundice that other reasons causes, diagnosable is acute icterohepatitis.

3, Therapeutic Method

3.1 prescriptions: Herba Artemisiae Scopariae 30g, Rhizoma Imperatae 30g, Flos Lonicerae 30g, Fructus Forsythiae 30g, Catechu 20g, Semen Cajani 20g, Cortex Moutan 20g, Rhizoma Menispermi 20g, Rhizoma Atractylodis Macrocephalae 10g, Radix Bupleuri 10g, Radix Glycyrrhizae 10g.

3.2 methods of preparation and use: said medicine routinely technique is made decoction, every day 2 times, 7 days are a course for the treatment of at 1 dose of oral every day.

4, therapeutic outcome:

4.1 formulate with reference to < < Chinese medicine Clinical Researches of New Drugs guideline > >:

Recovery from illness: transference cure, skin, yellow sclera and sign disappear, and liver function recovery is normal, and serum total bilirubin is down to below 17 μ mol/L;

Effective: symptom obviously changes, skin, yellow sclera and sign take a favorable turn, and serum total bilirubin drops to 17-25.5 μ mol/L; Effective: symptom makes moderate progress, skin, yellow sclera and sign take a turn for the better, and serum total bilirubin drops to 25.6-34 μ mol/L; Invalid: symptom is without improvement, sign, serum total bilirubin is unchanged, even increase the weight of.

4.2 results: in 95 routine patients, 73 examples of fully recovering (76.8%), effective 16 examples (16.8%), effective 3 examples (3.2%), invalid 3 examples (3.2%), total effective rate is 96.8%.

5, model case

5.1 are permitted certain, female, 37 years old, because of occur together heat 3 days of unable 1 week companion's xanthochromia of anorexia, time have right flank portion dull pain uncomfortable, the nausea of feeling sick, yellow urine, normally, red tongue tongue is greasy in vain for stool, slippery and rapid pulse is diagnosed as acute icterohepatitisshock.Take medicine of the present invention, 1 dose of every day, after 1 course for the treatment of, symptom is clearly better, sclera, xanthochromia is clearly better, continue to take 1 the course for the treatment of xanthochromia and transference cure, blood test liver function is normal, serum total bilirubin 17 μ mol/L, recovery from illness, follows up a case by regular visits to after 1 year without recurrence.

5.2 Guo, man, 46 years old, there is fever with aversion to cold in patient before 1 week, nausea and vomiting continues and sees skin, yellow sclera, bright and lustrous, gastral cavilty distension, inappetence, total bilirubin 28 μ mol/L.Swelling under liver right flank, pain.Red tongue, yellow and greasy fur, wiry and frequent pulse, treasure is broken as acute icterohepatitis.Take medicine of the present invention, treat 1 course for the treatment of, symptom obviously alleviates, and continues to take 2 courses for the treatment of, and total bilirubin is 16.8 μ mol/L recoveries from illness, follows up a case by regular visits to without recurrence after half a year.

The specific embodiment

Embodiment 1, and a kind of Chinese medicine for the treatment of acute icterohepatitis is to be made by Herba Artemisiae Scopariae 20g, Rhizoma Imperatae 20g, Flos Lonicerae 20g, Fructus Forsythiae 20g, Catechu 15g, Semen Cajani 15g, Cortex Moutan 15g, Rhizoma Menispermi 15g, Rhizoma Atractylodis Macrocephalae 8g, Radix Bupleuri 8g, Radix Glycyrrhizae 8g.

Embodiment 2, and a kind of Chinese medicine for the treatment of acute icterohepatitis is to be made by Herba Artemisiae Scopariae 30g, Rhizoma Imperatae 30g, Flos Lonicerae 30g, Fructus Forsythiae 30g, Catechu 20g, Semen Cajani 20g, Cortex Moutan 20g, Rhizoma Menispermi 20g, Rhizoma Atractylodis Macrocephalae 10g, Radix Bupleuri 10g, Radix Glycyrrhizae 10g.

Embodiment 3, and a kind of Chinese medicine for the treatment of acute icterohepatitis is to be made by Herba Artemisiae Scopariae 40g, Rhizoma Imperatae 40g, Flos Lonicerae 40g, Fructus Forsythiae 40g, Catechu 25g, Semen Cajani 25g, Cortex Moutan 25g, Rhizoma Menispermi 25g, Rhizoma Atractylodis Macrocephalae 15g, Radix Bupleuri 15g, Radix Glycyrrhizae 15g.

Claims (2)

1. treat a Chinese medicine for acute icterohepatitis, it is characterized in that it is to be made by following raw material medicaments:

Herba Melasmatis arvensis 30-50 part, ten liang of leaf 20-40 parts, Rabdosia stracheyi(Benth.ex Hook.f.)Hara[Plectranthus stracheyi Benth.ex Hook.f. 20-40 part, Flos Lonicerae 20-40 part, Rhizoma Angiopteridis Officinalis 20-40 part, Catechu 15-25 part, Semen Cajani 15-25 part, Rhizoma Menispermi 15-25 part, Radix Et Rhizoma Rhei 10-20 part, Pericarpium Arecae 10-20 part, Rhizoma Atractylodis Macrocephalae 8-15 part, Radix Glycyrrhizae 8-15 part.

2. Chinese medicine according to claim 1, is characterized in that it is to be made by following raw material medicaments:

30 parts, 40 parts, ten liang leaves of Herba Melasmatis arvensis, 30 parts of Rabdosia stracheyi(Benth.ex Hook.f.)Hara[Plectranthus stracheyi Benth.ex Hook.f., 30 parts of Flos Loniceraes, 30 parts of Rhizoma Angiopteridis Officinaliss, 20 parts of Catechu, 20 parts of Semen Cajanis, 20 parts of Rhizoma Menispermis, 15 parts of Radix Et Rhizoma Rhei, 15 parts of Pericarpium Arecae, 10 parts of the Rhizoma Atractylodis Macrocephalaes, 10 parts, Radix Glycyrrhizae.