CN105054045A - Calcium tablet special for children and preparation method of calcium tablet - Google Patents
Calcium tablet special for children and preparation method of calcium tablet Download PDFInfo
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- CN105054045A CN105054045A CN201510590225.1A CN201510590225A CN105054045A CN 105054045 A CN105054045 A CN 105054045A CN 201510590225 A CN201510590225 A CN 201510590225A CN 105054045 A CN105054045 A CN 105054045A
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- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 title claims abstract description 44
- 239000011575 calcium Substances 0.000 title claims abstract description 44
- 229910052791 calcium Inorganic materials 0.000 title claims abstract description 44
- 238000002360 preparation method Methods 0.000 title claims abstract description 18
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims abstract description 75
- 239000000843 powder Substances 0.000 claims abstract description 72
- 235000001674 Agaricus brunnescens Nutrition 0.000 claims abstract description 47
- 150000001875 compounds Chemical class 0.000 claims abstract description 41
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims abstract description 28
- 229910000019 calcium carbonate Inorganic materials 0.000 claims abstract description 14
- 241000167854 Bourreria succulenta Species 0.000 claims abstract description 13
- 239000004375 Dextrin Substances 0.000 claims abstract description 13
- 229920001353 Dextrin Polymers 0.000 claims abstract description 13
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 13
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims abstract description 13
- 229920002774 Maltodextrin Polymers 0.000 claims abstract description 13
- 239000005913 Maltodextrin Substances 0.000 claims abstract description 13
- 235000019693 cherries Nutrition 0.000 claims abstract description 13
- 235000019425 dextrin Nutrition 0.000 claims abstract description 13
- 239000008103 glucose Substances 0.000 claims abstract description 13
- 229940035034 maltodextrin Drugs 0.000 claims abstract description 13
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 13
- 244000234623 Coprinus comatus Species 0.000 claims abstract description 11
- 235000004439 Coprinus comatus Nutrition 0.000 claims abstract description 11
- 244000252132 Pleurotus eryngii Species 0.000 claims abstract description 11
- 235000001681 Pleurotus eryngii Nutrition 0.000 claims abstract description 11
- 239000002994 raw material Substances 0.000 claims abstract description 11
- 238000002156 mixing Methods 0.000 claims description 20
- 239000000203 mixture Substances 0.000 claims description 17
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 claims description 15
- 235000020985 whole grains Nutrition 0.000 claims description 15
- 239000002245 particle Substances 0.000 claims description 13
- 239000008213 purified water Substances 0.000 claims description 12
- 240000006794 Volvariella volvacea Species 0.000 claims description 11
- 238000000034 method Methods 0.000 claims description 9
- 241000233866 Fungi Species 0.000 claims description 7
- 239000000463 material Substances 0.000 claims description 6
- DKHJWWRYTONYHB-UHFFFAOYSA-N CPP Chemical compound OC(=O)C(C)OC1=CC=C(Cl)C=C1 DKHJWWRYTONYHB-UHFFFAOYSA-N 0.000 claims description 5
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 claims description 5
- 239000005025 cast polypropylene Substances 0.000 claims description 5
- 238000005469 granulation Methods 0.000 claims description 5
- 230000003179 granulation Effects 0.000 claims description 5
- 239000008188 pellet Substances 0.000 claims description 5
- 238000005453 pelletization Methods 0.000 claims description 5
- 239000012856 weighed raw material Substances 0.000 claims description 5
- 244000003416 Asparagus officinalis Species 0.000 claims description 4
- 235000005340 Asparagus officinalis Nutrition 0.000 claims description 4
- 238000010298 pulverizing process Methods 0.000 claims description 2
- 238000010521 absorption reaction Methods 0.000 abstract description 5
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 abstract description 2
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 abstract description 2
- 150000001720 carbohydrates Chemical class 0.000 abstract description 2
- 230000036737 immune function Effects 0.000 abstract description 2
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract description 2
- 239000011777 magnesium Substances 0.000 abstract description 2
- 229910052749 magnesium Inorganic materials 0.000 abstract description 2
- 239000011707 mineral Substances 0.000 abstract description 2
- 102000004169 proteins and genes Human genes 0.000 abstract description 2
- 108090000623 proteins and genes Proteins 0.000 abstract description 2
- 229930003231 vitamin Natural products 0.000 abstract description 2
- 229940088594 vitamin Drugs 0.000 abstract description 2
- 235000013343 vitamin Nutrition 0.000 abstract description 2
- 239000011782 vitamin Substances 0.000 abstract description 2
- 239000011701 zinc Substances 0.000 abstract description 2
- 229910052725 zinc Inorganic materials 0.000 abstract description 2
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 abstract 2
- 240000006499 Flammulina velutipes Species 0.000 abstract 1
- 235000016640 Flammulina velutipes Nutrition 0.000 abstract 1
- 235000001715 Lentinula edodes Nutrition 0.000 abstract 1
- 240000000599 Lentinula edodes Species 0.000 abstract 1
- 108010001441 Phosphopeptides Proteins 0.000 abstract 1
- 241000222350 Pleurotus Species 0.000 abstract 1
- 235000014633 carbohydrates Nutrition 0.000 abstract 1
- 239000005018 casein Substances 0.000 abstract 1
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 abstract 1
- 235000021240 caseins Nutrition 0.000 abstract 1
- 235000019359 magnesium stearate Nutrition 0.000 abstract 1
- 235000010755 mineral Nutrition 0.000 abstract 1
- 235000018102 proteins Nutrition 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 235000013305 food Nutrition 0.000 description 7
- 239000000047 product Substances 0.000 description 4
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 description 3
- 239000004472 Lysine Substances 0.000 description 3
- 229930003316 Vitamin D Natural products 0.000 description 3
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 235000016709 nutrition Nutrition 0.000 description 3
- 235000019166 vitamin D Nutrition 0.000 description 3
- 239000011710 vitamin D Substances 0.000 description 3
- 150000003710 vitamin D derivatives Chemical class 0.000 description 3
- 229940046008 vitamin d Drugs 0.000 description 3
- 230000009286 beneficial effect Effects 0.000 description 2
- 238000002372 labelling Methods 0.000 description 2
- 239000000314 lubricant Substances 0.000 description 2
- 235000012054 meals Nutrition 0.000 description 2
- 238000012216 screening Methods 0.000 description 2
- OILXMJHPFNGGTO-UHFFFAOYSA-N (22E)-(24xi)-24-methylcholesta-5,22-dien-3beta-ol Natural products C1C=C2CC(O)CCC2(C)C2C1C1CCC(C(C)C=CC(C)C(C)C)C1(C)CC2 OILXMJHPFNGGTO-UHFFFAOYSA-N 0.000 description 1
- RQOCXCFLRBRBCS-UHFFFAOYSA-N (22E)-cholesta-5,7,22-trien-3beta-ol Natural products C1C(O)CCC2(C)C(CCC3(C(C(C)C=CCC(C)C)CCC33)C)C3=CC=C21 RQOCXCFLRBRBCS-UHFFFAOYSA-N 0.000 description 1
- OQMZNAMGEHIHNN-UHFFFAOYSA-N 7-Dehydrostigmasterol Natural products C1C(O)CCC2(C)C(CCC3(C(C(C)C=CC(CC)C(C)C)CCC33)C)C3=CC=C21 OQMZNAMGEHIHNN-UHFFFAOYSA-N 0.000 description 1
- 206010006956 Calcium deficiency Diseases 0.000 description 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- DNVPQKQSNYMLRS-NXVQYWJNSA-N Ergosterol Natural products CC(C)[C@@H](C)C=C[C@H](C)[C@H]1CC[C@H]2C3=CC=C4C[C@@H](O)CC[C@]4(C)[C@@H]3CC[C@]12C DNVPQKQSNYMLRS-NXVQYWJNSA-N 0.000 description 1
- 244000068988 Glycine max Species 0.000 description 1
- 235000010469 Glycine max Nutrition 0.000 description 1
- IMQLKJBTEOYOSI-GPIVLXJGSA-N Inositol-hexakisphosphate Chemical compound OP(O)(=O)O[C@H]1[C@H](OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@@H]1OP(O)(O)=O IMQLKJBTEOYOSI-GPIVLXJGSA-N 0.000 description 1
- 244000017020 Ipomoea batatas Species 0.000 description 1
- 235000002678 Ipomoea batatas Nutrition 0.000 description 1
- IMQLKJBTEOYOSI-UHFFFAOYSA-N Phytic acid Natural products OP(O)(=O)OC1C(OP(O)(O)=O)C(OP(O)(O)=O)C(OP(O)(O)=O)C(OP(O)(O)=O)C1OP(O)(O)=O IMQLKJBTEOYOSI-UHFFFAOYSA-N 0.000 description 1
- 241000206607 Porphyra umbilicalis Species 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 235000019606 astringent taste Nutrition 0.000 description 1
- 230000003185 calcium uptake Effects 0.000 description 1
- MWKXCSMICWVRGW-UHFFFAOYSA-N calcium;phosphane Chemical compound P.[Ca] MWKXCSMICWVRGW-UHFFFAOYSA-N 0.000 description 1
- 239000010949 copper Substances 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 235000018823 dietary intake Nutrition 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- DNVPQKQSNYMLRS-SOWFXMKYSA-N ergosterol Chemical compound C1[C@@H](O)CC[C@]2(C)[C@H](CC[C@]3([C@H]([C@H](C)/C=C/[C@@H](C)C(C)C)CC[C@H]33)C)C3=CC=C21 DNVPQKQSNYMLRS-SOWFXMKYSA-N 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 238000005461 lubrication Methods 0.000 description 1
- 235000018977 lysine Nutrition 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 239000002366 mineral element Substances 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 235000008935 nutritious Nutrition 0.000 description 1
- 239000000467 phytic acid Substances 0.000 description 1
- 229940068041 phytic acid Drugs 0.000 description 1
- 235000002949 phytic acid Nutrition 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 235000019640 taste Nutrition 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention belongs to the technical field of calcium tablets, and particularly relates to a calcium tablet special for children and a preparation method of the calcium tablet. The calcium tablet is prepared from raw material components in parts by weight: 410 to 450 parts of calcium carbonate, 1.5 to 2.5 parts of casein phosphopeptides, 590 to 610 parts of glucose, 78 to 82 parts of dextrin, 5 to 10 parts of cherry essence, 17 parts of citric acid, 3 parts of water, 6.1 parts of edible alcohol, 44 to 50 parts of maltodextrin, 10 to 14 parts of magnesium stearate and 50 to 70 parts of compound mushroom powder, wherein the compound mushroom powder is prepared from pleurotus eryngii powder, volvaria volvacea powder, lentinus edodes powder, coprinus comatus powder, pleurotus geesteranus powder and flammulina velutipes powder in a certain mass ratio. The compound mushroom powder is rich in protein, carbohydrate, vitamins and mineral substances such as calcium, magnesium and zinc, the rapid absorption of calcium can be promoted, and the immunologic function of children can be increased.
Description
Technical field
The invention belongs to the preparation field of calcium tablet, be specifically related to a kind of children special-purpose calcium tablet and preparation method thereof.
Background technology
The calcareous crowd to each age group has important trophism.According to the result of national nutrition survey in 2002, the most obvious with calcium deficiency in our people's diet nutritional intake.Along with the raising of living standards of the people, the demand of people to supplementary calcium food and calcium preparation increases day by day.The meals composition of China is based on plant food, and calcium content is few, and the abundant food of calcium content is few, and calcium phosphorus ratio is seriously inverted, and is unfavorable for absorbing of calcium, has that phytic acid content is high etc. is multiplely unfavorable for the factor that calcium uptake utilizes in meals simultaneously.And a lot of children exist defect particular about food, cause calcium and nutritional labeling insufficiency of intake, impact is grown normally.
Though the food of numerous commercial ca preparation and strengthening calcium is had existing, most ofs expensive, and taste liking not by children, be difficult to popularization, and the effect of supplemented calcium of most products itself and absorption rate are also required study.
The mushroom classes such as pleurotus eryngii, straw mushroom, White mushroom, coprinus comatus are nutritious, are rich in the mineral matter such as protein, carbohydrate, vitamin and calcium, magnesium, copper, zinc, can improve the immunologic function of human body, promote the absorption of calcium, supplement each nutritional labeling needed for children.
Summary of the invention
The object of the invention is to for the deficiencies in the prior art, a kind of children special-purpose calcium tablet and preparation method thereof is provided.The compound mushroom powder of amino acid, microorganism and various mineral element is rich in the present invention by adding in calcium tablet, be conducive to children physique and intelligence development, and promote the absorption of calcium, impart calcium tablet health-care effect, is suitable for 4 ~ 13 years old children and eats.
For achieving the above object, the present invention adopts following technical scheme:
A kind of children special-purpose calcium tablet, by weight, its raw material consists of: 410 ~ 450 parts, calcium carbonate, CPP 1.5 ~ 2.5 parts, glucose 590 ~ 610 parts, 78 ~ 82 parts, dextrin, cherry essence 5 ~ 10 parts, citric acid 17 parts, purified water 3 parts, edible alcohol 6.1 parts, maltodextrin 44 ~ 50 parts, dolomol 10 ~ 14 parts, 50 ~ 70 parts, compound mushroom powder.
Described children special-purpose calcium tablet, by weight, its raw material composition is preferably: 435 parts, calcium carbonate, CPP 1.9 parts, glucose 600 parts, 80.8 parts, dextrin, cherry essence 7 parts, citric acid 17 parts, purified water 3 parts, edible alcohol 6.1 parts, maltodextrin 46.3 parts, dolomol 12 parts, 50 parts, compound mushroom powder.
Its composition of described compound mushroom powder is counted by weight: 10 ~ 12 parts, pleurotus eryngii powder, 5 ~ 7 parts, straw mushroom powder, mushroom powder 15 ~ 20 parts, 12 ~ 16 parts, coprinus comatus powder, pleurotusgeesteranuspowder powder 3 ~ 5 parts, golden needle fungus 9 ~ 13 parts.
Its composition of described compound mushroom powder is preferably by weight: 10 parts, pleurotus eryngii powder, 7 parts, straw mushroom powder, mushroom powder 20 parts, 14 parts, coprinus comatus powder, pleurotusgeesteranuspowder powder 5 parts, golden needle fungus 13 parts.
The method processed of described compound mushroom powder is: be 6% ~ 10% by fresh pleurotus eryngii, straw mushroom, mushroom, coprinus comatus, elegant precious mushroom, asparagus sun cured to moisture content, crosses 100 mesh sieves, mix in proportion after pulverizing respectively, obtained compound mushroom powder.
A preparation method for children special-purpose calcium tablet as above, comprises the following steps:
(1) prepare burden: weighed raw material respectively by formula rate; After load weighted calcium carbonate, CPP, glucose, maltodextrin, dextrin mixing 20min, obtained compound;
(2) solution preparation: citric acid purified water dissolved, adds edible alcohol and is deployed into citric acid solution;
(3) mixing granulation: the compound that step (1) is obtained is placed in efficient wet granulator, adds citric acid solution, by the operation of efficient wet granulator S.O.P., makes 16 object wet granulars;
(4) dry: first open HighefficientFluidbeddrier, more slowly sent in HighefficientFluidbeddrier by wet granular, temperature controls at 65 DEG C, and vapor tension control, at 0.15MPa, is dried to pellet moisture and is down to less than 5%;
(5) whole grain: the efficient pelletizing machine of dried particle is passed through the whole grain of 14 mesh sieve;
(6) always mix: the material after whole grain is added in two-dimensional motion mixer, add compound mushroom powder, dolomol, cherry essence, mixing 10min;
(7) compressing tablet: the hopper that the particle after mixing is placed in rotary tablet machine is carried out compressing tablet, in tableting processes, every 30min survey sheet is heavy once, controls every sheet at 1.20-1.25g/ sheet.
beneficial effect of the present invention is:
1) the present invention adds compound mushroom powder in calcium tablet, and in the edible mushroom such as straw mushroom, asparagus, lysine content enriches, and lysine is conducive to children physique and intelligence development, and asparagus is called " increasing intelligence mushroom " especially in Japan; Compound mushroom powder is made an addition in calcium tablet, effectively can improve lysine content, be conducive to children physique and intelligence development;
2) the present invention adds compound mushroom powder in calcium tablet, be conducive to the absorptivity improving calcium, this is because mushroom vitamin D content is up to 128 international units, it is 8 times of laver, 7 times of sweet potato, 21 times of soybean, under solar drying, ergosterol changes more vitamin D into, and vitamin D can promote the absorption to calcium; Improve the absorptivity of calcium;
3) in screening this product formulation procedures, be studied from many aspects such as the advantageous feature of raw material legitimacy, security, raw material, add the astringent taste that compound mushroom powder is conducive to covering calcium carbonate, make the mouthfeel of this product better, more welcome by children.
Detailed description of the invention
The present invention's the following example further illustrates the present invention, but protection scope of the present invention is not limited to the following example.
embodiment 1
A kind of children special-purpose calcium tablet, its raw material consists of: calcium carbonate 435g, CPP 1.9g, glucose 600g, dextrin 80.8g, cherry essence 7g, citric acid 17g, purified water 3g, edible alcohol 6.1g, maltodextrin 46.3g, dolomol 12g, compound mushroom powder 50g;
Its composition of compound mushroom powder is counted by weight: 10 parts, pleurotus eryngii powder, 7 parts, straw mushroom powder, mushroom powder 20 parts, 14 parts, coprinus comatus powder, pleurotusgeesteranuspowder powder 5 parts, golden needle fungus 13 parts;
Preparation method, concrete steps are:
(1) prepare burden: weighed raw material respectively by formula rate; After load weighted calcium carbonate, CPP, glucose, maltodextrin, dextrin mixing 20min, obtained compound;
(2) solution preparation: citric acid purified water dissolved, adds edible alcohol and is deployed into citric acid solution;
(3) mixing granulation: the compound that step (1) is obtained is placed in efficient wet granulator, adds citric acid solution, by the operation of efficient wet granulator S.O.P., makes 16 object wet granulars;
(4) dry: first open HighefficientFluidbeddrier, more slowly sent in HighefficientFluidbeddrier by wet granular, temperature controls at 65 DEG C, and vapor tension control, at 0.15MPa, is dried to pellet moisture and is down to less than 5%;
(5) whole grain: the efficient pelletizing machine of dried particle is passed through the whole grain of 14 mesh sieve;
(6) always mix: the material after whole grain is added in two-dimensional motion mixer, add compound mushroom powder, dolomol, cherry essence, mixing 10min;
(7) compressing tablet: the hopper that the particle after mixing is placed in rotary tablet machine is carried out compressing tablet, in tableting processes, every 30min survey sheet is heavy once, controls every sheet at 1.20-1.25g/ sheet, makes 1000.
embodiment 2
A kind of children special-purpose calcium tablet, its raw material consists of: calcium carbonate 410g, CPP 1.5g, glucose 610g, dextrin 78g, cherry essence 5g, citric acid 17g, purified water 3g, edible alcohol 6.1g, maltodextrin 47.4g, dolomol 12g, compound mushroom powder 69.1g;
Its composition of compound mushroom powder is counted by weight: 12 parts, pleurotus eryngii powder, 5 parts, straw mushroom powder, mushroom powder 18 parts, 16 parts, coprinus comatus powder, pleurotusgeesteranuspowder powder 3 parts, golden needle fungus 9 parts;
Preparation method, concrete steps are:
(1) prepare burden: weighed raw material respectively by formula rate; After load weighted calcium carbonate, CPP, glucose, maltodextrin, dextrin mixing 20min, obtained compound;
(2) solution preparation: citric acid purified water dissolved, adds edible alcohol and is deployed into citric acid solution;
(3) mixing granulation: the compound that step (1) is obtained is placed in efficient wet granulator, adds citric acid solution, by the operation of efficient wet granulator S.O.P., makes 16 object wet granulars;
(4) dry: first open HighefficientFluidbeddrier, more slowly sent in HighefficientFluidbeddrier by wet granular, temperature controls at 65 DEG C, and vapor tension control, at 0.15MPa, is dried to pellet moisture and is down to less than 5%;
(5) whole grain: the efficient pelletizing machine of dried particle is passed through the whole grain of 14 mesh sieve;
(6) always mix: the material after whole grain is added in two-dimensional motion mixer, add compound mushroom powder, dolomol, cherry essence, mixing 10min;
(7) compressing tablet: the hopper that the particle after mixing is placed in rotary tablet machine is carried out compressing tablet, in tableting processes, every 30min survey sheet is heavy once, controls every sheet at 1.20-1.25g/ sheet, makes 1000,1.25g/ sheet.
embodiment 3
A kind of children special-purpose calcium tablet, its raw material consists of: calcium carbonate 435.4g, CPP 2.5g, glucose 590g, dextrin 82g, cherry essence 10g, citric acid 17g, purified water 3g, edible alcohol 6.1g, maltodextrin 44g, dolomol 10g, compound mushroom powder 59.1g;
Its composition of described compound mushroom powder is counted by weight: 11 parts, pleurotus eryngii powder, 7 parts, straw mushroom powder, mushroom powder 15 parts, 12 parts, coprinus comatus powder, pleurotusgeesteranuspowder powder 5 parts, golden needle fungus 9 parts;
Preparation method, concrete steps are:
(1) prepare burden: weighed raw material respectively by formula rate; After load weighted calcium carbonate, CPP, glucose, maltodextrin, dextrin mixing 20min, obtained compound;
(2) solution preparation: citric acid purified water dissolved, adds edible alcohol and is deployed into citric acid solution;
(3) mixing granulation: the compound that step (1) is obtained is placed in efficient wet granulator, adds citric acid solution, by the operation of efficient wet granulator S.O.P., makes 16 object wet granulars;
(4) dry: first open HighefficientFluidbeddrier, more slowly sent in HighefficientFluidbeddrier by wet granular, temperature controls at 65 DEG C, and vapor tension control, at 0.15MPa, is dried to pellet moisture and is down to less than 5%;
(5) whole grain: the efficient pelletizing machine of dried particle is passed through the whole grain of 14 mesh sieve;
(6) always mix: the material after whole grain is added in two-dimensional motion mixer, add compound mushroom powder, dolomol, cherry essence, mixing 10min;
(7) compressing tablet: the hopper that the particle after mixing is placed in rotary tablet machine is carried out compressing tablet, in tableting processes, every 30min survey sheet is heavy once, controls every sheet at 1.20-1.25g/ sheet, makes 1000.
The eating method of this product and amount: chew food, 4 ~ 13 years old children, every day 2 (1.25g/ sheet).
conditional filtering:
1)the consumption of citric acid and essence is on the impact of mouthfeel
The consumption of table 1 citric acid and essence is on the impact of mouthfeel
2) screening of lubricant quantity
Raw materials particles adds a certain amount of material with lubrication before compressing tablet, to increase the mobility of particle, reduces the friction between particle and punch die, is beneficial to tablet to release nib, makes the dosage of tablet accurate, unilateral bright and clean attractive in appearance.Lubricity, the Adhesion Resistance of various lubricant, fluidity is helped respectively to have pluses and minuses.The most frequently used is dolomol.When dolomol consumption is the 0.8-1% of sheet weight, effect is best.
Table 2 dolomol consumption is on the impact of compressing tablet
3) efficacy assessments
table 34 ~ 13 year old children's invented food calcium takes in information slip
The foregoing is only preferred embodiment of the present invention, all equalizations done according to the present patent application the scope of the claims change and modify, and all should belong to covering scope of the present invention.
Claims (6)
1. a children special-purpose calcium tablet, is characterized in that: by weight, and its raw material consists of: 410 ~ 450 parts, calcium carbonate, CPP 1.5 ~ 2.5 parts, glucose 590 ~ 610 parts, 78 ~ 82 parts, dextrin, cherry essence 5 ~ 10 parts, citric acid 17 parts, purified water 3 parts, edible alcohol 6.1 parts, maltodextrin 44 ~ 50 parts, dolomol 10 ~ 14 parts, 50 ~ 70 parts, compound mushroom powder.
2. children special-purpose calcium tablet according to claim 1, is characterized in that: by weight, and its raw material consists of: 435 parts, calcium carbonate, CPP 1.9 parts, glucose 600 parts, 80.8 parts, dextrin, cherry essence 7 parts, citric acid 17 parts, purified water 3 parts, edible alcohol 6.1 parts, maltodextrin 46.3 parts, dolomol 12 parts, 50 parts, compound mushroom powder.
3. children special-purpose calcium tablet according to claim 1, is characterized in that: its composition of described compound mushroom powder is counted by weight: 10 ~ 12 parts, pleurotus eryngii powder, 5 ~ 7 parts, straw mushroom powder, mushroom powder 15 ~ 20 parts, 12 ~ 16 parts, coprinus comatus powder, pleurotusgeesteranuspowder powder 3 ~ 5 parts, golden needle fungus 9 ~ 13 parts.
4. children special-purpose calcium tablet according to claim 3, is characterized in that: its composition of described compound mushroom powder is counted by weight: 10 parts, pleurotus eryngii powder, 7 parts, straw mushroom powder, mushroom powder 20 parts, 14 parts, coprinus comatus powder, pleurotusgeesteranuspowder powder 5 parts, golden needle fungus 13 parts.
5. the children special-purpose calcium tablet according to claim 3 or 4, it is characterized in that: the method processed of described compound mushroom powder is: be 6% ~ 10% by fresh pleurotus eryngii, straw mushroom, mushroom, coprinus comatus, elegant precious mushroom, asparagus sun cured to moisture content, 100 mesh sieves are crossed after pulverizing respectively, mix in proportion, obtained compound mushroom powder.
6. a preparation method for children special-purpose calcium tablet as claimed in claim 1, is characterized in that: comprise the following steps:
(1) prepare burden: weighed raw material respectively by formula rate; After load weighted calcium carbonate, CPP, glucose, maltodextrin, dextrin mixing 20min, obtained compound;
(2) solution preparation: citric acid purified water dissolved, adds edible alcohol and is deployed into citric acid solution;
(3) mixing granulation: the compound that step (1) is obtained is placed in efficient wet granulator, adds citric acid solution, by the operation of efficient wet granulator S.O.P., makes 16 object wet granulars;
(4) dry: first open HighefficientFluidbeddrier, more slowly sent in HighefficientFluidbeddrier by wet granular, temperature controls at 65 DEG C, and vapor tension control, at 0.15MPa, is dried to pellet moisture and is down to less than 5%;
(5) whole grain: the efficient pelletizing machine of dried particle is passed through the whole grain of 14 mesh sieve;
(6) always mix: the material after whole grain is added in two-dimensional motion mixer, add compound mushroom powder, dolomol, cherry essence, mixing 10min;
(7) compressing tablet: the hopper that the particle after mixing is placed in rotary tablet machine is carried out compressing tablet, in tableting processes, every 30min survey sheet is heavy once, controls every sheet at 1.20-1.25g/ sheet.
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| CN106722991A (en) * | 2016-12-21 | 2017-05-31 | 赣州天润药业有限公司 | A kind of calcium tablet and preparation method thereof |
| CN107996796A (en) * | 2017-12-29 | 2018-05-08 | 宣城柏维力生物工程有限公司 | A kind of sea algae calcium pressed candy and preparation method thereof |
| CN109846901A (en) * | 2019-04-03 | 2019-06-07 | 江西安顺堂生物科技有限公司 | It is a kind of to promote bone growth, anti-caries, the preparation and preparation process for supplementing calcium |
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