CN105050566B - 具有外部智能的药物输送胶囊 - Google Patents
具有外部智能的药物输送胶囊 Download PDFInfo
- Publication number
- CN105050566B CN105050566B CN201380063998.3A CN201380063998A CN105050566B CN 105050566 B CN105050566 B CN 105050566B CN 201380063998 A CN201380063998 A CN 201380063998A CN 105050566 B CN105050566 B CN 105050566B
- Authority
- CN
- China
- Prior art keywords
- capsule
- medicament
- capsules
- triggering event
- activator
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
- A61J7/0076—Medicament distribution means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
- A61J7/04—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
- A61J7/0409—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers
- A61J7/0481—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers working on a schedule basis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
- A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
- G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
- G16H20/13—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered from dispensers
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16Z—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS, NOT OTHERWISE PROVIDED FOR
- G16Z99/00—Subject matter not provided for in other main groups of this subclass
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
- A61B2560/02—Operational features
- A61B2560/0266—Operational features for monitoring or limiting apparatus function
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/16—Details of sensor housings or probes; Details of structural supports for sensors
- A61B2562/162—Capsule shaped sensor housings, e.g. for swallowing or implantation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/07—Endoradiosondes
- A61B5/073—Intestinal transmitters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
- A61B5/6861—Capsules, e.g. for swallowing or implanting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J2200/00—General characteristics or adaptations
- A61J2200/70—Device provided with specific sensor or indicating means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
- A61J7/04—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
- A61J7/0409—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers
- A61J7/0418—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers with electronic history memory
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
- A61J7/04—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
- A61J7/0409—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers
- A61J7/0427—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers with direct interaction with a dispensing or delivery system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
- A61K51/1258—Pills, tablets, lozenges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D83/00—Containers or packages with special means for dispensing contents
- B65D83/04—Containers or packages with special means for dispensing contents for dispensing annular, disc-shaped, or spherical or like small articles, e.g. tablets or pills
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D83/00—Containers or packages with special means for dispensing contents
- B65D83/04—Containers or packages with special means for dispensing contents for dispensing annular, disc-shaped, or spherical or like small articles, e.g. tablets or pills
- B65D83/0409—Containers or packages with special means for dispensing contents for dispensing annular, disc-shaped, or spherical or like small articles, e.g. tablets or pills the dispensing means being adapted for delivering one article, or a single dose, upon each actuation
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Primary Health Care (AREA)
- Epidemiology (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
Description
Claims (21)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261711627P | 2012-10-09 | 2012-10-09 | |
US61/711627 | 2012-10-09 | ||
PCT/US2013/061202 WO2014058605A1 (en) | 2012-10-09 | 2013-09-23 | Drug delivery capsules with external intelligence |
Publications (2)
Publication Number | Publication Date |
---|---|
CN105050566A CN105050566A (zh) | 2015-11-11 |
CN105050566B true CN105050566B (zh) | 2020-09-22 |
Family
ID=50477779
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201380063998.3A Expired - Fee Related CN105050566B (zh) | 2012-10-09 | 2013-09-23 | 具有外部智能的药物输送胶囊 |
Country Status (5)
Country | Link |
---|---|
US (2) | US9918904B2 (zh) |
EP (1) | EP2906175B1 (zh) |
JP (1) | JP6283677B2 (zh) |
CN (1) | CN105050566B (zh) |
WO (1) | WO2014058605A1 (zh) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9937124B2 (en) | 2014-09-11 | 2018-04-10 | International Business Machines Corporation | Microchip substance delivery devices having low-power electromechanical release mechanisms |
US10881788B2 (en) | 2015-10-30 | 2021-01-05 | International Business Machines Corporation | Delivery device including reactive material for programmable discrete delivery of a substance |
US10286198B2 (en) * | 2016-04-08 | 2019-05-14 | International Business Machines Corporation | Microchip medical substance delivery devices |
US20170347952A1 (en) * | 2016-06-06 | 2017-12-07 | Rainbow Medical Ltd. | Sensors for oral dosage forms |
JP2020524062A (ja) * | 2017-05-19 | 2020-08-13 | シャロン、ティドハー | 胃腸サンプルを収集するためのデバイスと方法 |
US11241562B2 (en) | 2018-03-13 | 2022-02-08 | Progenity, Inc. | Ingestible device with relatively large payload volume |
CN108338789B (zh) * | 2018-04-10 | 2023-12-19 | 上海臣邦医药科技股份有限公司 | 一种智能胶囊 |
US10835685B2 (en) * | 2018-05-30 | 2020-11-17 | Amgen Inc. | Thermal spring release mechanism for a drug delivery device |
US11160730B2 (en) * | 2018-06-11 | 2021-11-02 | Rightis Technology, LLC | Smart medication dispensing system and method |
GB201900780D0 (en) * | 2019-01-21 | 2019-03-06 | Vibrant Ltd | Device and method for delivering a flowable ingestible medicament into the gastrointestinal tract of a user |
KR20220016176A (ko) | 2019-05-29 | 2022-02-08 | 인큐브 랩스 엘엘씨 | 치료 제제를 투여하기 위한 장치 및 방법 |
JP7070806B2 (ja) * | 2019-11-07 | 2022-05-18 | 株式会社村田製作所 | 服用検知システムおよび服薬デバイス |
JP2023536760A (ja) * | 2020-08-08 | 2023-08-29 | ノボ・ノルデイスク・エー/エス | 内腔に挿入可能なカプセル |
FR3125962A1 (fr) * | 2021-08-05 | 2023-02-10 | La Valériane | Dispositif et système de dispensation de médicament |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4731765A (en) * | 1986-08-25 | 1988-03-15 | Cole George W | Medi minder |
US4844076A (en) * | 1988-08-26 | 1989-07-04 | The Johns Hopkins University | Ingestible size continuously transmitting temperature monitoring pill |
JPH0713715Y2 (ja) * | 1990-07-06 | 1995-04-05 | ミヤリサン株式会社 | 医療用カプセル |
US5217449A (en) * | 1990-12-11 | 1993-06-08 | Miyarisan Kabushiki Kaisha | Medical capsule and apparatus for activating the same |
US5860957A (en) | 1997-02-07 | 1999-01-19 | Sarcos, Inc. | Multipathway electronically-controlled drug delivery system |
US6764446B2 (en) * | 2000-10-16 | 2004-07-20 | Remon Medical Technologies Ltd | Implantable pressure sensors and methods for making and using them |
US6929636B1 (en) | 2000-11-08 | 2005-08-16 | Hewlett-Packard Development Company, L.P. | Internal drug dispenser capsule medical device |
CN101010114B (zh) * | 2004-08-27 | 2010-05-26 | 皇家飞利浦电子股份有限公司 | 电子遥控药丸和用于供应至少一种药物的系统 |
WO2006077528A2 (en) * | 2005-01-18 | 2006-07-27 | Koninklijke Philips Electronics, N.V. | Electronically controlled capsule |
US8021357B2 (en) * | 2005-05-27 | 2011-09-20 | Olympus Corporation | Body-insertable apparatus |
US8636172B2 (en) * | 2006-01-05 | 2014-01-28 | Lawrence A. Dunn | Devices, systems and methods for point-of-use medication control |
US8147482B2 (en) | 2006-06-20 | 2012-04-03 | MEDIMETRICS Personalized Drug Delivery B.V. | Electronic capsule for treating gastrointestinal disease |
RU2009123434A (ru) * | 2006-11-21 | 2010-12-27 | Конинклейке Филипс Электроникс Н.В. (Nl) | Желудочная электронная капсула и система диагностики или доставки лекарственного средства внутрь живого организма |
WO2008064428A1 (en) * | 2006-11-29 | 2008-06-05 | Bray Kenmar | Medicament dispensing device |
FR2927068B1 (fr) * | 2008-02-05 | 2012-12-07 | Lvmh Rech | Dispositif de distribution pour produit fluide et procede de distribution |
JP5681861B2 (ja) * | 2008-03-31 | 2015-03-11 | メディメトリクス ペルソナリズド ドルグ デリヴェリー ベー ヴェ | センサを有する嚥下型カプセルを作成する方法 |
JP5188880B2 (ja) * | 2008-05-26 | 2013-04-24 | オリンパスメディカルシステムズ株式会社 | カプセル型医療装置およびカプセル型医療装置の充電方法 |
JP4869312B2 (ja) * | 2008-10-06 | 2012-02-08 | オリンパス株式会社 | カプセル型医療装置 |
CN102209487B (zh) * | 2008-11-13 | 2013-12-18 | 奥林巴斯医疗株式会社 | 胶囊型医疗装置 |
JP5263742B2 (ja) * | 2009-01-26 | 2013-08-14 | 国立大学法人 筑波大学 | 服用者を見守る服薬確認システム |
EP2464413B1 (en) * | 2009-08-12 | 2013-10-16 | Medimetrics Personalized Drug Delivery B.V. | Medicine reservoir for drug delivery device |
EP2512321A1 (en) * | 2009-12-17 | 2012-10-24 | Koninklijke Philips Electronics N.V. | Swallowable capsule for monitoring a condition |
EP2571573A4 (en) * | 2010-03-17 | 2013-12-04 | Photopill Medical Ltd | PHOTOTHERAPY BY CAPSULE |
US8776802B2 (en) * | 2010-08-25 | 2014-07-15 | Brown University | Methods and systems for prolonged localization of drug delivery |
-
2013
- 2013-09-23 CN CN201380063998.3A patent/CN105050566B/zh not_active Expired - Fee Related
- 2013-09-23 WO PCT/US2013/061202 patent/WO2014058605A1/en active Application Filing
- 2013-09-23 US US14/434,548 patent/US9918904B2/en active Active
- 2013-09-23 EP EP13846079.5A patent/EP2906175B1/en active Active
- 2013-09-23 JP JP2015536790A patent/JP6283677B2/ja not_active Expired - Fee Related
-
2018
- 2018-02-02 US US15/887,371 patent/US20180271752A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2014058605A1 (en) | 2014-04-17 |
EP2906175B1 (en) | 2018-11-07 |
EP2906175A1 (en) | 2015-08-19 |
EP2906175A4 (en) | 2016-06-22 |
JP6283677B2 (ja) | 2018-02-21 |
CN105050566A (zh) | 2015-11-11 |
JP2015531298A (ja) | 2015-11-02 |
US20150272830A1 (en) | 2015-10-01 |
US9918904B2 (en) | 2018-03-20 |
US20180271752A1 (en) | 2018-09-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20180327 Address after: Heilbronn Applicant after: Storck 10 Co.,Ltd. Address before: American New York Applicant before: MEDIMETRICS PERSONALIZED DRUG DELIVERY |
|
TA01 | Transfer of patent application right | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20180627 Address after: American California Applicant after: Baozhenati Address before: Heilbronn Applicant before: Storck 10 Co.,Ltd. |
|
TA01 | Transfer of patent application right | ||
GR01 | Patent grant | ||
GR01 | Patent grant | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20200922 |
|
CF01 | Termination of patent right due to non-payment of annual fee |