CN105031278A - Traditional Chinese medicine for treating filariasis - Google Patents
Traditional Chinese medicine for treating filariasis Download PDFInfo
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- CN105031278A CN105031278A CN201510535526.4A CN201510535526A CN105031278A CN 105031278 A CN105031278 A CN 105031278A CN 201510535526 A CN201510535526 A CN 201510535526A CN 105031278 A CN105031278 A CN 105031278A
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Abstract
The invention relates to a traditional Chinese medicine for treating filariasis. The traditional Chinese medicine is prepared from the following medicinal raw materials in parts by weight: 15 parts of asparagus, 10 parts of tongking pepper, 12 parts of mosla dianthera, 10 parts of lacerate wood fern rhizome or leaf, 3 parts of agalloch eaglewood, 25 parts of perfoliote knotweed herb, 5 parts of aconitum pseudostapfianum and 20 parts of indian zehneria herb. Clinical experiments prove that the traditional Chinese medicine can be used for treating filariasis safely and effectively.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine being used for the treatment of filaricide.
Background technology
Filaricide colonizes in human body by filaricide, by mosquitoes spread, be colonize in a kind of chronic infectious disease that the places such as human lymphoid's system, subcutaneous tissue, abdominal cavity, thoracic cavity, cardiovascular and pericardial cavity cause due to filaricide.Clinical manifestation is the lymphangitis of recurrent exerbation, lymphadenitis and heating with acute, chronic for lymphedema and elephatiasis etc. be main, particularly bancroftosis also can cause hydrocele of tunica vaginalis and chyluria etc.There is eosinophilia in slight fever, blood incubation period; Sometimes clinical manifestation is that pulmonary's eosinophilic granulocyte infiltrates syndrome, the symptoms such as the hot fear of cold that can occur together, cough uncomfortable in chest, asthma.
Pathogenesis: filaricide mostly occurs in the rainy season of area of heavy rainfull, now rain is wet more very, forces under sky summer-heat in addition, and ground wets upper steaming, so that damp and hot inclined Sheng, invade body, struggle between vital QI and pathogen, checks Wei Yang, to block mechanism of qi, and see the card such as fever with chills, cough uncomfortable in chest, notably strongly fragrant and heat-transformation, pyretic toxicity is partially contained and sees the card such as " red muscle is swollen ", " erysipelas ".Pathogenic factor delay is not gone, and The length of time will create dislike, and all kinds of diseases and ailments are by giving birth to.Damp and hot resistance network, three burnt heap soil or fertilizer over and around the rootss are stagnant, and water channel is obstructed, or deficiency of spleen and stomach, gasifies not all right, all can cause retention of water-damp, and overflowing is swollen in skin.Retention of damp-heat in the interior, spleen loses the duty of ascending the clear and descending the turbid or sinking of QI due to deficiency of the spleen, and suffering from a deficiency of the kidney can not store essential substances, then precise and tinyly see nebulousurine with letting out under drowning.
Medical material present Research involved in the present invention is as follows:
Asparagus [another name] Radix Asparagi Officinalis, mountain Herba Asparagi Setacei, Germinatus Phragmitis, Germinatus Phragmitis, Asparagus officinalis, Thallus Gracilariae.[source] is the tuber of liliaceous plant asparagus.Spring, autumn dig tuber, clean, and boiled water dries after scalding.[nature and flavor] slightly warm in nature, hides hardship, micro-pungent.[return through] returns kidney channel.[function cures mainly] lung moistening antitussive, eliminate the phlegm parasite killing.For cough due to lung-heat, kill infantile malnutrition worm; External treatment skin scabies and parasite.[usage and dosage] takes orally: decoct soup, 15 ~ 30g.[extracts] " China's book on Chinese herbal medicine ".
Herba Piperris Tonkinensis [another name] askew leaf orchid, little Herba Piperris Tonkinensis, large hemorrhoidal hamorrhage, ramie leaf beach wormwood.[source] Piperaceae Piper plant optical axis ramie leaf Betel, is used as medicine with root or Herb.The whole year can adopt, and section is dried.[nature and flavor] are pungent, temperature.[return through] Liver Channel.[function cures mainly] expelling wind and cold, eliminating stasis to stop pain.For flu, bones and muscles pain due to rheumatism, treating swelling and pain by traumatic injury, dysmenorrhea, amenorrhea, cold syndrome of the stomach pain; Poisonous snake, centipete bite are controlled in external.[usage and dosage] takes orally: decoct soup, 3 ~ 16g.[extracts] " China's book on Chinese herbal medicine ".
Mosla dianthera [another name] Herba Chenopodii, artificial fish perfume, wild Herba Moslae, miliaria alba grass, miliaria careless, the moon taste grass, the Flos Carthami moon taste grass, Rhizoma Zingiberis Recens mustard, Rabdosia stracheyi(Benth.ex Hook.f.)Hara[Plectranthus stracheyi Benth.ex Hook.f., mountain Perilla frutescens, flower thinning shepherd's purse be peaceful.The little seafood grass of the peaceful platymiscium of [source] Labiatae stone shepherd's purse, with all herbal medicine.Xia Qiu gathers, and cleans, using fresh herb or dry.[nature and flavor] are pungent, temperature.[return through] returns kidney, spleen two warp.[function cures mainly] is dispeled the wind and is delivered, and dampness removing is antipruritic.For headache due to common cold, tonsillitis, heatstroke, Peptic Ulcers, dysentery; Eczema is controlled in external, miliaria, skin pruritus, furuncle, centipete bite.[usage and dosage] takes orally: decoct soup, 9 ~ 15g.[extracts] " China's book on Chinese herbal medicine ".
The half of grass of Dryopteris lacera (Thunb.) O. Ktze. [another name], burr are yellow.The rhizome that [source] is Dryopteridaceae plant narrow top shield-fern and leaf.Gather and store: rhizome all can be gathered the whole year.Dig out afterwash, defoliation handle and fibrous root; Leaf children adopts time tender.Using fresh herb or dry.[nature and flavor] micro-hardship; Cool.[return through] spleen channel.[function cures mainly] heat clearing away; Invigorate blood circulation; Parasite killing.Main traumatic injury; Dysentery; Taeniasis.[usage and dosage] takes orally: decoct soup, 5 ~ 10g.[extracts] " China's book on Chinese herbal medicine ".
Gal is muttered, and perfume (or spice) [another name] agalloch eaglewood, fine jade are muttered, strange nanmu.The timber containing volume resin that [source] is Isolated From Thymelaeaceae Species Lignum Aquilariae Resinatum or the nearly root of Lignum Aquilariae Resinatum.Choose Lignum Aquilariae Resinatum medium oil (resin) foot, body constitution is heavy and timber stick that property is glutinous, its oil-containing of pruning is few and part that color is light.[nature and flavor] acrid in the mouth is peppery, and temperature is nontoxic.[return through] returns lung meridian.[function cures mainly] regulates the flow of vital energy, and pain relieving is sensible.Control and uncomfortable in chestly not relax, stagnation of QI pain, wind-phlegm is inaccessible.Merit victory Lignum Aquilariae Resinatum.[usage and dosage] takes orally: decoct soup, 1 ~ 3g.[extracts] " China's book on Chinese herbal medicine ".
Herba Polygoni cymosi [another name] Herba Lespedezae Cuneatae, colter thorn, river Pennisetum centrasiaticum Tzvel, ant grasshopper le, urgency are separated element, tiger Lei, ram's horn thorn, Herba Polygoni cymosi, She Yacao, are worn leaf knotweed.[source] passes through the herb of leaf knotweed for Polygonaceae arsesmart.Gather during summer fall planting strain riotous growth, dry.[nature and flavor] acid, cool.[return through] returns kidney, lung two warp.[function cures mainly] heat-clearing and toxic substances removing, inducing diuresis to remove edema.For upper respiratory tract infection, tracheitis, pertussis, acute tonsillitis, enteritis, dysentery, oedema due to nephritis; Herpes zoster is controlled in external, eczema, carbuncle furuncle and phyma poison, venom.[usage and dosage] takes orally: decoct soup, 25 ~ 30g.[extracts] " China's book on Chinese herbal medicine ".
Evil mind solution [source] medical material Ji Yuan: be the tuber of ranunculaceae plant Yulong Aconitum carmichjaelii Debx. and Aconitum pseudostapfianum W. T. Wang..Gather and store: summer, autumn excavate, and remove stem and leaf, cleaning, using fresh herb or dry.[nature and flavor] acrid in the mouth; Bitter; Warm in nature; [return through] enters Liver Channel.[function cures mainly] wind-damp dispelling; Pain relieving.Main air pain of dampness syndrome; Lumbago and skelalgia.[usage and dosage] takes orally: decoct soup, 3 ~ 5g.[extracts] " China's book on Chinese herbal medicine ".
Horse hail [another name] mouse load Fructus Benincasae, wild Fructus Momordicae charantiae, clasp grass, beautiful button.[source] medical material Ji Yuan: be the herb of cucurbitaceous plant Herba Zehneriae Indicae.Gather and store: summer, autumn gather, and dig tuber, removing mud and radicula, cleaning, cut sheet; Stem and leaf shreds, using fresh herb or dry.[nature and flavor] sweet in the mouth; Bitter; Cool in nature.[return through] lung; Liver; Spleen channel.[function cures mainly] heat-clearing and toxic substances removing; Dispersing swelling and dissipating binds; To reduce phlegm diuresis.Main carbuncle furuncle swells; Sucutaneous nodule scrofula; Laryngopharynx swelling and pain; Mumps; Stranguria caused by urinary stone; Dysuria; Skin eczema; Conjunctival congestion jaundice; Hemorrhoid complicated by anal fistula; Proctoptosis; Traumatic hemorrhage; Venom.[usage and dosage] takes orally: decoct soup, 15 ~ 30g.[extracts] " China's book on Chinese herbal medicine ".
Summary of the invention
The present invention aims to provide a kind of Chinese medicine being used for the treatment of filaricide, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing filaricide.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine being used for the treatment of filaricide, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: asparagus 15 parts, Herba Piperris Tonkinensis 10 parts, Mosla dianthera 12 parts, Dryopteris lacera (Thunb.) O. Ktze. 10 parts, gal mutter fragrant 3 parts, Herba Polygoni cymosi 25 parts, evil mind solution 5 parts, horse hail 20 parts.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Outpatient service is collected and filaricide patient 85 example of being in hospital altogether in inventor in October, 2012 ~ 2013 between year October, be divided into treatment group 45 example and matched group 40 example at random, treatment group man 28 example, female 17 example, 20 ~ 57 years old age; Matched group man 21 example, female 19 example, 18 ~ 68 years old age.2 groups of sexes, age and course of disease comparing difference not statistically significants, have comparability.
Diagnostic criteria
Diagnostic criteria according to the meeting of national filaricide clinical speciality:
Western medicine diagnose:
1. mosquito bite history is had in Endemic Area.
2. acute stage, shows as lymphangitis, lymphadenitis, erysipelas sample dermatitis, spermatitis, epididymitis, orchitis.Heating can, in periodically, also can cause pulmonary's eosinophil to infiltrate syndrome.
3. there is the symptom of lymph node and lymphatic vessel blocking, as lymph varix, hydrocele of tunica vaginalis, chyluria, elephatiasis etc. in chronic phase.
4. night thick smear method or concentration method find microfilariae of ohchocerciasis in blood around.
Also microfilariae of ohchocerciasis can be found in the liquid such as lymphatic vessel, scrotum hydrocele of tunica vaginalis, chyluria of varicose.
The lymphatic vessel tuberosity of parts of body or enlarged lymph node do biopsy can find adult (lymph node that groin is larger should not cut, in order to avoid increase the weight of lymphatic block and form lymphatic fistula).
5. to the suspected patient that can not find microfilariae of ohchocerciasis in blood, praziquantel can be tried out and do diagnostic treatment (praziquantel 1Omg/kg decoction being taken at a draught), then get tuberosity and find adult as check pathological section.
The traditional Chinese medical science is differentiated:
1. acute superficial lymphangitis: have skin injury, Herba Peristrophis Roxburghianae sample scorching hot pain in local has from bottom to top Xiang the feature of Xing core development, and local pain and tenderness are all more acute, and in blood, neutrophilic leukocytosis is main more.
2. epididymal tuberculosis: should differentiate mutually with epididymal tuberculosis with the tuberosity swelling at spermatic cord, scrotum place in early days.The latter's tuberosity, in epididymis, often sticks together, not bitterly, rare recurrent exerbation; And the tuberosity of filaricide often adheres on spermatic cord, epididymis, pain, has the feature of recurrent exerbation.
2, test method
2.1 Therapeutic Method
The capsule that the oral the present invention for the treatment of group obtains according to specific embodiment 3, every day 3 times.It within 7th, is a course for the treatment of.
The oral Hetrazan 200mg of matched group, points three times oral, within 7th, is a course for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Cure: symptom, sign disappear, and hemogram is normal; Blood examination microfilariae of ohchocerciasis 3 feminine genders.
Effective: chronic phase physical signs of patient stablize; Blood examination microfilariae of ohchocerciasis 3 feminine genders.
Invalid: symptom, sign, lab testing are without improvement.
3.2 therapeutic outcomes are in table 1.
Table 1 liang group comparitive study
| Group | n | Cure | Effectively | Invalid | Total effective rate (%) | Serious adverse reaction example |
| Treatment group | 45 | 9 | 31 | 5 | 88.89% | 0 |
| Matched group | 40 | 3 | 22 | 15 | 62.50% | 0 |
Visible, the medicine that the present invention obtains can safe and effective treatment filaricide, has promotional value.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Embodiment 1
Take: asparagus 15 grams, Herba Piperris Tonkinensis 10 grams, Mosla dianthera 12 grams, Dryopteris lacera (Thunb.) O. Ktze. 10 grams, gal mutter fragrant 3 grams, Herba Polygoni cymosi 25 grams, evil mind solution 5 grams, horse hail 20 grams; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.
Be used for the treatment of filaricide.Oral, every bu Morning Afternoon Evening is taken for three times.
Embodiment 2
Take: asparagus 15 grams, Herba Piperris Tonkinensis 10 grams, Mosla dianthera 12 grams, Dryopteris lacera (Thunb.) O. Ktze. 10 grams, gal mutter fragrant 3 grams, Herba Polygoni cymosi 25 grams, evil mind solution 5 grams, horse hail 20 grams; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.
Be used for the treatment of filaricide.Oral, every bu Morning Afternoon Evening is taken for three times.
Embodiment 3
Take: asparagus 15 grams, Herba Piperris Tonkinensis 10 grams, Mosla dianthera 12 grams, Dryopteris lacera (Thunb.) O. Ktze. 10 grams, gal mutter fragrant 3 grams, Herba Polygoni cymosi 25 grams, evil mind solution 5 grams, horse hail 20 grams; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.
Be used for the treatment of filaricide.Oral, every bu Morning Afternoon Evening is taken for three times.
Claims (4)
1. one kind is used for the treatment of the Chinese medicine of filaricide, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: asparagus 15 parts, Herba Piperris Tonkinensis 10 parts, Mosla dianthera 12 parts, Dryopteris lacera (Thunb.) O. Ktze. 10 parts, gal mutter fragrant 3 parts, Herba Polygoni cymosi 25 parts, evil mind solution 5 parts, horse hail 20 parts.
2. as claimed in claim 1 for the Chinese medicine of filaricide, it is characterized in that, its preparation method is: take: asparagus 15 parts, Herba Piperris Tonkinensis 10 parts, Mosla dianthera 12 parts, Dryopteris lacera (Thunb.) O. Ktze. 10 parts, gal mutter fragrant 3 parts, Herba Polygoni cymosi 25 parts, evil mind solution 5 parts, horse hail 20 parts; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 parts, obtains decoct; Above-mentioned part all refers to weight portion.
3. be used for the treatment of the Chinese medicine of filaricide as claimed in claim 1, it is characterized in that, its preparation method is: take: asparagus 15 parts, Herba Piperris Tonkinensis 10 parts, Mosla dianthera 12 parts, Dryopteris lacera (Thunb.) O. Ktze. 10 parts, gal mutter fragrant 3 parts, Herba Polygoni cymosi 25 parts, evil mind solution 5 parts, horse hail 20 parts; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, obtains powder; Above-mentioned part all refers to weight portion.
4. be used for the treatment of the Chinese medicine of filaricide as claimed in claim 1, it is characterized in that, its preparation method is: take: asparagus 15 parts, Herba Piperris Tonkinensis 10 parts, Mosla dianthera 12 parts, Dryopteris lacera (Thunb.) O. Ktze. 10 parts, gal mutter fragrant 3 parts, Herba Polygoni cymosi 25 parts, evil mind solution 5 parts, horse hail 20 parts; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, obtains capsule; Above-mentioned part all refers to weight portion.
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| CN201510535526.4A CN105031278A (en) | 2015-08-28 | 2015-08-28 | Traditional Chinese medicine for treating filariasis |
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| CN201510535526.4A CN105031278A (en) | 2015-08-28 | 2015-08-28 | Traditional Chinese medicine for treating filariasis |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5535055A (en) * | 1978-09-05 | 1980-03-11 | Isamu Oishi | Prevention of dog against filariasis |
| CN104161900A (en) * | 2013-05-18 | 2014-11-26 | 刘兴朋 | Traditional Chinese medicine for treating filariasis |
| CN104758440A (en) * | 2015-03-30 | 2015-07-08 | 淄博夸克医药技术有限公司 | Traditional Chinese medicine for treating ischialgia |
-
2015
- 2015-08-28 CN CN201510535526.4A patent/CN105031278A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5535055A (en) * | 1978-09-05 | 1980-03-11 | Isamu Oishi | Prevention of dog against filariasis |
| CN104161900A (en) * | 2013-05-18 | 2014-11-26 | 刘兴朋 | Traditional Chinese medicine for treating filariasis |
| CN104758440A (en) * | 2015-03-30 | 2015-07-08 | 淄博夸克医药技术有限公司 | Traditional Chinese medicine for treating ischialgia |
Non-Patent Citations (1)
| Title |
|---|
| 《健康大讲堂》编委会: "《<本草纲目>对症速查手册》", 31 May 2013, 黑龙江科学技术出版社 * |
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