CN104815299A - Traditional Chinese medicine for treating fatty liver - Google Patents
Traditional Chinese medicine for treating fatty liver Download PDFInfo
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- CN104815299A CN104815299A CN201510287060.0A CN201510287060A CN104815299A CN 104815299 A CN104815299 A CN 104815299A CN 201510287060 A CN201510287060 A CN 201510287060A CN 104815299 A CN104815299 A CN 104815299A
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Abstract
The invention relates to a traditional Chinese medicine for treating fatty liver. The traditional Chinese medicine for treating the fatty liver is prepared from the following raw herbal materials in parts by weight: 30 parts of artemisia capillaries, 30 parts of seed of longleaf xylosma, 6 parts of froggrass, 6 parts of toosendan fruit, 6 parts of rhizoma corydalis, 10 parts of trogopterus dung, 15 parts of indigo naturalis, 15 parts of Eupolyphoge sinensis and 6 parts of radix curcumae. The clinical experiment shows that the fatty liver can be safely and effectively treated by the traditional Chinese medicine.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine being used for the treatment of fatty liver.
Background technology
Fatty liver means athero in the hepatocyte that a variety of causes causes, and is common clinical manifestation.The fat content of normal liver accounts for 5% of liver weight in wet base, is mainly phospholipid (60%), triglyceride (20%) and a small amount of fatty acid, cholesterol and cholesteryl ester.When intrahepatic fat content exceedes 10% of liver weight in wet base, or when histologically more than 50% hepatocyte has a steatosis, claim fatty liver.Fatty liver is not an independently disease, and can be caused by many reasons.The Pathological of fatty liver only can have the thin steatosis of liver.Also Periportal fibrosis and inflammatory cell infiltration can be accompanied, or in fatty cirrhosis.Hepatic cell fattydegeneration also only can betide local and form Focal Fatty Liver.Motherland's medical science, without the name of disease of " fatty liver ", can belong to the category of " hypochondriac pain ", " gathering " etc.Most scholar thinks that its cause of disease is full of with surfeit delicious food savoury, insobriety, lying on bed for a long time sitting, the rich expectorant of body, it is relevant to experience Shi Re Bing Pian, disorder of emotion, weakness due to chronic disease etc.Motherland's medical science is thought, the most common cause of fatty liver is eating and drinking without temperance, and surfeit delicious food savoury, drinks wantonly, chronic stimulation, and excessive idleness moves less, obesity etc.These factors very easily cause liver spleen impaired, the liver failing to maintain the normal flow of QI, dysfunction of the spleen in transportation.Thus cause the turbid interior life of expectorant, qi depression to blood stasis, stagnation in liver meridian.Therefore clinical treatment is often with soothing liver and strengthening spleen, it is main that removing dampness removing food stagnancy eliminates the phlegm.Water wets, expectorant is turbid, blood stasis plays a crucial role in the generation evolution of fatty liver.
Medical material present Research involved in the present invention is as follows:
Herba Artemisiae Scopariae [another name] because of dirt, Ma Xian, mattress Gall Artemisia, Herba Artemisiae Scopariae, because of Herba Artemisiae Scopariae, capillary wormwood, floss Artemisia, spire Herba Artemisiae Annuae, smelly Artemisia, An Lvcao, grandmother Artemisia, Radix Rhapontici Artemisia.The young young stem and leaf that [source] is feverfew Herba Artemisiae Scopariae.Gather during seedling height about three cun in spring, removing impurity, removes earth, dries.[nature and flavor] toil, cool.[return through] enters liver, spleen, urinary bladder channel.[function cures mainly] clearing away heat-damp and promoting diuresis.Control jaundice due to damp-heat, dysuria, pruritus due to wind pathogen skin ulcer scabies.Join Fructus Gardeniae, Radix Et Rhizoma Rhei controls YANG jaundice; Join Radix Aconiti Lateralis Preparata, Rhizoma Zingiberis controls YIN jaundice.[usage and dosage] takes orally: decoct soup, 9 ~ 15g.Clothes are avoided in the damp and hot jaundice caused of [attention] unprovoked.[extracts] " China's book on Chinese herbal medicine ".
Break by a fall and strangle [another name] little Fructus Gleditsia acupuncture, lignumvitae, chisel tree.The leaf that [source] is Flacourtiaceae plant longleaf xylosma, thorn and seed.Gather and store: leaf, thorn all can be adopted the whole year; Gather during fruit maturation, dry; Leaf using fresh herb.[nature and flavor] bitter in the mouth; Puckery; Cold in nature.[return through] enters spleen, stomach, Liver Channel.[function cures mainly] clearing away heat-damp and promoting diuresis; Blood circulation promoting and blood stasis dispelling; Reducing swelling and alleviating pain; Lactogenic.Main jaundice; Edema; Traumatic injury; Fracture; Amenorrhea; Carbuncle sore tumefacting virus; Galactostasis; Skin ulcer tinea; Scrofula.[usage and dosage] takes orally: decoct soup, 6 ~ 12g.[attention] polyphagia consumption gas, damages tooth, easily hungry, on an empty stomach and thin and weak people or void avoid it after being ill.[extracts] " China's book on Chinese herbal medicine ".
Salicornia Bigelovii Torr. [another name] Cao Yanjiao, cramp dish, salt calabash, fat Herba Artemisiae grass, wax candle Herba Artemisiae, extra large fat person, Hai Jiacai.The herb of [source] chenopod salicornia europaeal.Gather and store: summer gathers in herb, cleaning and dry.[nature and flavor] bitter, sweet, flat.[return through] GUIXIN, liver, large intestine channel.[function cures mainly] suppressing the hyperactive liver; Diuresis; Blood pressure lowering.Main hypertension; Headache.[usage and dosage] takes orally: decoct soup, 9 ~ 15g.[extracts] " China's book on Chinese herbal medicine ".
Fructus Toosendan [another name] Fructus Toosendan, Fructus Toosendan are real.[source] this product is the dry mature fruit of Meliaceae plant Fructus Toosendan.Gather during fruit maturation in winter, removing impurity, dry.[nature and flavor] are bitter, cold.[return through] returns liver, small intestinal, urinary bladder channel.[function cures mainly] soothing liver-QI promoting the circulation of QI to relieve pain, anthelmintic.For the breast side of body, abdominal distention, colic, abdominal pain due to worm stagnation.[usage and dosage] takes orally: decoct soup, 4.5 ~ 9g.[attention] Deficiency and coldness of spleen and stomach person avoids clothes.Fructus Foeniculi makes .[take passages for it] " China's book on Chinese herbal medicine ".
Rhizoma Corydalis [another name] Rhizoma Corydalis element, Rhizoma Corydalis, Rhizoma Corydalis.[source] this product is the dry tuber of papaveraceae plant corydalis.Excavate when early summer stem and leaf is withered, removing fibrous root, cleans, and puts in boiling water and boils to during just without the white heart, take out, dry.[nature and flavor] are pungent, bitter, temperature.[return through] returns liver, spleen channel.[function cures mainly] invigorates blood circulation, promoting the circulation of QI, pain relieving.For the breast side of body, epigastric pain, amenorrhea dysmenorrhea, postpartum stagnation, tumbling and swelling.[usage and dosage] takes orally: decoct soup, 3-9g.[attention] anemia of pregnant woman is cautious use of.[extracts] " China's book on Chinese herbal medicine ".
Oletum Trogopterori [another name] Oletum Trogopterori, sugared Oletum Trogopterori, Oletum Trogopterori rice, Oletum Trogopterori block.[source] is flying squirrel section animal trogopterus xanthipes or the dry feces flying the little flying squirrel of murine.The whole year can be received and be adopted.By the Ex-all of the impurity such as sandstone, earth.[nature and flavor] are sweet, temperature.[return through] enters liver, spleen channel.[function cures mainly] promoting blood circulation to remove blood stasis, parch to black stops blooding.Have a pain for trusted subordinate's congestion, dysmenorrhea, blood stasis amenorrhea, puerperal abdominalgia with blood stasis; Parch to black controls metrostaxis; Traumatic injury is controlled in external, Serpentis, insect bite wound.[usage and dosage] takes orally: decoct soup, 3 ~ 6g.[attention] abdominal pain due to deficiency of blood, blood deficiency amenorrhea, puerpera dehematizes and too much faints, and fire of having had a guilty conscience is had a pain, the sick blood deficiency that belongs to without the stagnant person of the stasis of blood, all work as and avoid [extractss] " Chinese herbal ".
Indigo Naturalis [another name] indigo, indigo flower, indigo foam, Isatis indigotica Fort (Indigofera tinctoria L, Baphicanthus cusia (nees) Brem. Polygonum tinctorium Ait).[source] this product is acanthaceous vegetable acanthaceous indigo, the leaf of polygonaceae plant polygonum tinctorium ait. or cruciferae isatis or stem and leaf be through processing obtained dried powder or agglomerate.[nature and flavor] are salty, cold.[return through] returns Liver Channel.[function cures mainly] heat-clearing and toxic substances removing, removing heat from blood, arresting convulsion.For maculae caused by violent heat pathogen, heat in blood tells nosebleed, chest pain hemoptysis, aphtha, mumps, sore throat, pediatric epilepsy scared.[usage and dosage] takes orally: decoct soup, 6 ~ 15g.[attention] invasion by pathogenic cold person do not make.[extracts] " China's book on Chinese herbal medicine ".
Eupolyphaga Seu Steleophaga [another name] Eupolyphaga Seu Steleophaga, eupolyphaga, DIWUGUI, female ground beetle.[source] this product is the female worm dry body of Corydiidae insecticide eupolyphoge sinensis or Ji eupolyphoge sinensis.After seizure, put in boiling water and scald extremely, dry or dry.[nature and flavor] are salty, cold; [return through] returns Liver Channel.[function cures mainly] removing blood stasis with potent drugs blood, reuniting the fractured tendons and bones.For injured bone, blood stasis amenorrhea, lump in the abdomen mass in the abdomen.[usage and dosage] takes orally: decoct soup, 3 ~ 9g.[attention] anemia of pregnant woman is forbidden.[extracts] " China's book on Chinese herbal medicine ".
Radix Curcumae [another name] radix curcumae, white silk Radix Curcumae.[source] this product is the dried root of zingiberaceous plant RADIX CURCUMAE, Rhizoma Curcumae Longae, Guangxi zedoary or Rhizoma Curcumae.The above two practise title " RADIX CURCUMAE " and " Radix Curcuma " respectively, and all the other are practised by character difference and claim " osmanthus Radix Curcumae " or " green filament Radix Curcumae ".Winter, stem and leaf was excavated after withering, and removing silt and radicula, steam or boil to the saturating heart, dry.[nature and flavor] are pungent, bitter, cold.[return through] returns liver, the heart, lung meridian.[function cures mainly] regulating qi to disperse stagnation, heart fire-clearing upset-relieving, promoting the function of the gallbladder to alleviate jaundice.For amenorrhea dysmenorrhea, chest and abdomen swelling and pain, twinge, calentura coma, epilepsy is gone mad, jaundice dark coloured urine.[usage and dosage] takes orally: decoct soup, 3 ~ 9g.[attention] deficiency of YIN is lost blood and avoids clothes without qi depression to blood stasis person, the careful clothes of anemia of pregnant woman.[extracts] " China's book on Chinese herbal medicine ".
Summary of the invention
The present invention aims to provide a kind of Chinese medicine being used for the treatment of fatty liver, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing fatty liver.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine being used for the treatment of fatty liver, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Herba Artemisiae Scopariae 30 parts, break by a fall strangle 30 parts, Salicornia Bigelovii Torr. 6 parts, Fructus Toosendan 6 parts, Rhizoma Corydalis 6 parts, Oletum Trogopterori 10 parts, Indigo Naturalis 15 parts, Eupolyphaga Seu Steleophaga 15 parts, Radix Curcumae 6 parts.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Outpatient service is collected and Patients with Fatty Liver 96 example of being in hospital altogether in inventor in October, 2012 ~ 2013 between year October, be divided into treatment group 48 example and matched group 48 example at random, 62 ~ 75 years old treatment group age, 65.10 years old mean age; 63 ~ 77 years old matched group age, 65.82 years old mean age.2 groups of ages and course of disease comparing difference not statistically significant, have comparability.
Diagnostic criteria
Diagnostic criteria according to the meeting of national fatty liver clinical speciality: the 1. first kind: insidious onset, the course of disease is long, and the state of an illness is lighter.Show as uncomfortable liver area or dull pain, abdominal distention, feel sick, hepatomegaly, matter are slightly hard, have slight tenderness.The longitude changes such as liver function has SGPT to increase.Reversible after treatment.Be mainly seen in primary hyperlipoproteinemia II, VI, V type (hypertriglyceridemia), diabetes, chronic alcoholism etc.Below check to help and examine (1) B ultrasonic and see hepatomegaly, CT shows that liver density lowers in various degree, and severe patient liver CT is negative value, and liver parenchyma density is lower than vessel density in liver, and slight liver fat infiltrates impact inspection and not easily finds; (2) blood fat (triglyceride is main) often raises; (3) liver biopsy can be made a definite diagnosis.Fat vacuole is had in hepatocyte under light microscopic.
2. Equations of The Second Kind: onset is anxious, state of an illness weight, and jaundice, ascites, bleeding tendency, renal failure, encephalopathy etc. can occur.Liver function is obviously abnormal.See acute fatty liver of pregnancy, liver huge piece of property steatosis-Reye syndrome (ReYe syndrome), tetracycline poisoning etc.Acute fatty liver can be diagnosed according to the cause of disease and clinical manifestation (comprising protopathy performance).
2, test method
2.1 Therapeutic Method
The capsule that the oral the present invention for the treatment of group obtains according to specific embodiment 3, every day 3 times.8 courses for the treatment of Monday.
The each 100mg of the oral cianidanol of matched group, 3 times/day.8 courses for the treatment of Monday.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Clinic control: through ultrasound diagnosis, clinically with following standard for the standard of curative effect evaluation: liver morphology returns to normal level;
Effective: if occur light once or on take a turn for the better;
Effective: occur taking a turn for the better but light once under;
Invalid: fatty liver symptom is without improvement or increase the weight of gradually.
3.2 therapeutic outcomes are in table 1.
Table 1 liang group comparitive study
Visible, the medicine that the present invention obtains can safe and effective treatment fatty liver, has promotional value.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Embodiment 1
Take: Herba Artemisiae Scopariae 30 grams, break by a fall strangle 30 grams, Salicornia Bigelovii Torr. 6 grams, Fructus Toosendan 6 grams, Rhizoma Corydalis 6 grams, Oletum Trogopterori 10 grams, Indigo Naturalis 15 grams, Eupolyphaga Seu Steleophaga 15 grams, Radix Curcumae 6 grams; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.
Be used for the treatment of fatty liver.Oral, every bu Morning Afternoon Evening is taken for three times.
Embodiment 2
Take: Herba Artemisiae Scopariae 30 grams, break by a fall strangle 30 grams, Salicornia Bigelovii Torr. 6 grams, Fructus Toosendan 6 grams, Rhizoma Corydalis 6 grams, Oletum Trogopterori 10 grams, Indigo Naturalis 15 grams, Eupolyphaga Seu Steleophaga 15 grams, Radix Curcumae 6 grams; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.
Be used for the treatment of fatty liver.Oral, every bu Morning Afternoon Evening is taken for three times.
Embodiment 3
Take: Herba Artemisiae Scopariae 30 grams, break by a fall strangle 30 grams, Salicornia Bigelovii Torr. 6 grams, Fructus Toosendan 6 grams, Rhizoma Corydalis 6 grams, Oletum Trogopterori 10 grams, Indigo Naturalis 15 grams, Eupolyphaga Seu Steleophaga 15 grams, Radix Curcumae 6 grams; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.
Be used for the treatment of fatty liver.Oral, every bu Morning Afternoon Evening is taken for three times.
Claims (4)
1. one kind is used for the treatment of the Chinese medicine of fatty liver, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Herba Artemisiae Scopariae 30 parts, break by a fall strangle 30 parts, Salicornia Bigelovii Torr. 6 parts, Fructus Toosendan 6 parts, Rhizoma Corydalis 6 parts, Oletum Trogopterori 10 parts, Indigo Naturalis 15 parts, Eupolyphaga Seu Steleophaga 15 parts, Radix Curcumae 6 parts.
2. be used for the treatment of the Chinese medicine of fatty liver as claimed in claim 1, it is characterized in that, its preparation method is: take: Herba Artemisiae Scopariae 30 parts, break by a fall strangle 30 parts, Salicornia Bigelovii Torr. 6 parts, Fructus Toosendan 6 parts, Rhizoma Corydalis 6 parts, Oletum Trogopterori 10 parts, Indigo Naturalis 15 parts, Eupolyphaga Seu Steleophaga 15 parts, Radix Curcumae 6 parts; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 parts, obtains decoct; Above-mentioned part all refers to weight portion.
3. be used for the treatment of the Chinese medicine of fatty liver as claimed in claim 1, it is characterized in that, its preparation method is: take: Herba Artemisiae Scopariae 30 parts, break by a fall strangle 30 parts, Salicornia Bigelovii Torr. 6 parts, Fructus Toosendan 6 parts, Rhizoma Corydalis 6 parts, Oletum Trogopterori 10 parts, Indigo Naturalis 15 parts, Eupolyphaga Seu Steleophaga 15 parts, Radix Curcumae 6 parts; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, obtains powder; Above-mentioned part all refers to weight portion.
4. be used for the treatment of the Chinese medicine of fatty liver as claimed in claim 1, it is characterized in that, its preparation method is: take: Herba Artemisiae Scopariae 30 parts, break by a fall strangle 30 parts, Salicornia Bigelovii Torr. 6 parts, Fructus Toosendan 6 parts, Rhizoma Corydalis 6 parts, Oletum Trogopterori 10 parts, Indigo Naturalis 15 parts, Eupolyphaga Seu Steleophaga 15 parts, Radix Curcumae 6 parts; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, obtains capsule; Above-mentioned part all refers to weight portion.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105434935A (en) * | 2015-12-17 | 2016-03-30 | 山东省立医院 | Traditional Chinese medicine used for treating fatty liver |
| CN105560696A (en) * | 2016-02-24 | 2016-05-11 | 宋云飞 | Drug for treating fatty liver |
| CN106753751A (en) * | 2016-12-13 | 2017-05-31 | 青岛嘉瑞生物技术有限公司 | A kind of glasswort nutrition oil for alleviating fatty liver |
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| CN101612222A (en) * | 2008-06-27 | 2009-12-30 | 韩庆亮 | A kind of Chinese drugs agentia for the treatment of fatty liver |
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| CN101612222A (en) * | 2008-06-27 | 2009-12-30 | 韩庆亮 | A kind of Chinese drugs agentia for the treatment of fatty liver |
| CN102058843A (en) * | 2010-11-24 | 2011-05-18 | 荣成市港圆抽纱制品有限公司 | Chinese medicine composition for treating fatty liver |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105434935A (en) * | 2015-12-17 | 2016-03-30 | 山东省立医院 | Traditional Chinese medicine used for treating fatty liver |
| CN105560696A (en) * | 2016-02-24 | 2016-05-11 | 宋云飞 | Drug for treating fatty liver |
| CN106753751A (en) * | 2016-12-13 | 2017-05-31 | 青岛嘉瑞生物技术有限公司 | A kind of glasswort nutrition oil for alleviating fatty liver |
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Application publication date: 20150805 |