CN105031193A - Tablet for treating influenza and preparation method thereof - Google Patents
Tablet for treating influenza and preparation method thereof Download PDFInfo
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- CN105031193A CN105031193A CN201510481971.7A CN201510481971A CN105031193A CN 105031193 A CN105031193 A CN 105031193A CN 201510481971 A CN201510481971 A CN 201510481971A CN 105031193 A CN105031193 A CN 105031193A
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Abstract
The invention discloses a tablet for treating influenza and a preparation method thereof, and belongs to the technical field of traditional Chinese medicine preparation. The tablet comprises starch, gypsum, crystal sugar, honey, magnesium stearate and a traditional Chinese medicine preparation. The tablet is prepared through the steps of crude product preparing, drying, sterilizing and the like. The tablet for treating the influenza integrates the effects of multiple traditional Chinese medicines, can achieve the effects of clearing heat, removing toxicity, inhibiting acute inflammation, eliminating phlegm, inhibiting bacteria, resisting virus and the like, and is rapid to take the effects, significant in treatment effect, safe and stable in medicine effect, high in cure rate and free of any side effects; the tablet is sterilized at high temperature under high pressure and is short in time, good in effect and long in preservation time.
Description
[technical field]
The invention belongs to Chinese drug preparation technique field, be specifically related to a kind of tablet for the treatment of flu and preparation method thereof.
[background technology]
Flu is a kind of commonly encountered diseases, many caused by Respirovirus, be wherein main viral with coronavirus and rhinovirus, clinical manifestation is its feature mainly with nasal obstruction, watery nasal discharge, cough, headache, aversion to cold, heating, general malaise etc., the whole year all can fall ill, especially common with spring.Meanwhile, flu is a kind of self-healing property disease, and the course of disease is generally seven days, and therefore, the quality of coldrex curative effect, is largely embodied in its onset speed.Present treatment flu Western medicine, mostly be symptomatic treatment, cure the symptoms, not the disease, therapeutic effect is limited, and has lethargy, the side effect such as listless, irritated after drug administration, and Western medicine price is costly.A lot of research shows that Chinese medicine is in treatment viral disease (as influenza A, atypical pneumonia), than Western medicine advantageously.
Theory of Chinese medical science is thought: catch a cold caused by being invaded by exogenous pathogen, the disease being located in the exterior, belongs to the sign of the traditional Chinese medical science, treats appropriate to the occasionly to disperse its table, it is generally acknowledged disease Shang Biao person, should relieving the exterior syndrome by diaphoresis eliminating evil.The Chinese medicine cold-treating preparation that current pharmaceutical factory produces, mostly is cool cold medicine, based on heat-clearing and toxic substances removing (as Radix Isatidis, summer Sang Ju Yin, silver-colored chrysanthemum common cold tablet etc.).This Chinese medicine cold-treating preparation is only applicable to the middle and advanced stage of anemopyretic cold or anemofrigid cold and has entered other diseases that inner heat-transformation becomes raw, and its onset is slow, and in body, good and evil hand over the time of striving long, after healing, vapour losses is many, and namely immunity, resistance decline, cause physical weakness, easily infect other diseases.At present some Chinese medicines with antivirus action are used alone effect and not obvious, but for the compound preparation of Coritab, current research fewer, the compound preparation of minority be also all formula simple, lack effectively, onset is slow, is difficult to the compound recipe advantageous effect realizing compound Chinese medicinal preparation.Therefore, share of Effect of Anti cold Chinese medicine, the compound recipe tablet producing effective anti-flu is significant.
[summary of the invention]
The invention provides a kind of tablet for the treatment of flu and preparation method thereof, the undesirable problem of curative effect is there is to solve the tablet for the treatment of flu in prior art, the present invention combines plurality of Chinese effect, can play suppress acute inflammation, eliminate the phlegm, the effect such as antibacterial, antiviral, the onset of this tablet treatment flu is rapid, evident in efficacy, and drug effect safety and stability, cure rate are high, without any side effects.
For solving above technical problem, the present invention by the following technical solutions:
A kind of tablet for the treatment of flu, in units of weight portion, comprise following raw material: starch 500-1500 part, Gypsum Fibrosum 200-600 part, crystal sugar 100-300 part, Mel 100-300 part, magnesium stearate 100-300 part, Chinese medicine preparation 200-400 part, described Chinese medicine preparation comprises following raw material: Pericarpium Citri Reticulatae 16-32 part, Radix Puerariae 16-32 part, Ramulus Cinnamomi 16-32 part, Rhizoma Et Radix Notopterygii 16-32 part, withered stalk 16-32 part, Herba Schizonepetae 12-24 part, Folium Perillae 12-24 part, Radix Bupleuri 12-24 part, Radix Saposhnikoviae 12-24 part, Rhizoma Chuanxiong 12-24 part, Radix Angelicae Dahuricae 8-16 part, Radix Rehmanniae 8-16 part, Rhizoma Atractylodis 8-16 part, Bulbus Fritillariae Cirrhosae 8-16 part, Cortex Fraxini 8-16 part, Pheretima 4-8 part, Herba Houttuyniae 4-8 part, Herba Asari 4-8 part, Radix Glycyrrhizae 4-8 part, Flos Lonicerae 4-8 part.
Preferably, the tablet of described treatment flu is in units of weight portion, comprise following raw material: starch 700-1300 part, Gypsum Fibrosum 300-500 part, crystal sugar 150-250 part, Mel 150-250 part, magnesium stearate 150-250 part, Chinese medicine preparation 250-350 part, described Chinese medicine preparation comprises following raw material: Pericarpium Citri Reticulatae 20-28 part, Radix Puerariae 20-28 part, Ramulus Cinnamomi 20-28 part, Rhizoma Et Radix Notopterygii 20-28 part, withered stalk 20-28 part, Herba Schizonepetae 15-21 part, Folium Perillae 15-21 part, Radix Bupleuri 15-21 part, Radix Saposhnikoviae 15-21 part, Rhizoma Chuanxiong 15-21 part, Radix Angelicae Dahuricae 10-14 part, Radix Rehmanniae 10-14 part, Rhizoma Atractylodis 10-14 part, Bulbus Fritillariae Cirrhosae 10-14 part, Cortex Fraxini 10-14 part, Pheretima 5-7 part, Herba Houttuyniae 5-7 part, Herba Asari 5-7 part, Radix Glycyrrhizae 5-7 part, Flos Lonicerae 5-7 part.
Preferably, the tablet of described treatment flu is in units of weight portion, comprise following raw material: starch 1000 parts, 400 parts, Gypsum Fibrosum, 200 parts, crystal sugar, Mel 200 parts, magnesium stearate 200 parts, Chinese medicine preparation 300 parts, described Chinese medicine preparation comprises following raw material: Pericarpium Citri Reticulatae 24 parts, Radix Puerariae 24 parts, Ramulus Cinnamomi 24 parts, Rhizoma Et Radix Notopterygii 24 parts, 24 parts, withered stalk, Herba Schizonepetae 18 parts, Folium Perillae 18 parts, Radix Bupleuri 18 parts, Radix Saposhnikoviae 18 parts, Rhizoma Chuanxiong 18 parts, the Radix Angelicae Dahuricae 12 parts, 12 parts, the Radix Rehmanniae, Rhizoma Atractylodis 12 parts, Bulbus Fritillariae Cirrhosae 12 parts, Cortex Fraxini 12 parts, Pheretima 6 parts, Herba Houttuyniae 6 parts, Herba Asari 6 parts, 6 parts, Radix Glycyrrhizae, Flos Lonicerae 6 parts.
The present invention also provides a kind of preparation method for the treatment of the tablet of flu, comprises the following steps:
S1, crude product are produced: the starch of described ratio, Gypsum Fibrosum, crystal sugar, Mel, magnesium stearate, Chinese medicine preparation mixing, add 200-1000 part water and make lamellar after stirring, the tablet crude product of obtained treatment flu;
S2, oven dry, sterilizing: the tablet crude product of the treatment flu that step S1 is obtained is dried, after sterilizing, the tablet of obtained treatment flu.
Preferably, the temperature of drying in step S2 is 80-100 DEG C, dries to water content≤6%, and the pressure of sterilizing is 210-230KPa, and the temperature of sterilizing is 134-136 DEG C, and the time of sterilizing is 6-8min.
Preferably, the preparation method of Chinese medicine preparation described in step S1 comprises the following steps:
S11: Pericarpium Citri Reticulatae, Radix Puerariae, Ramulus Cinnamomi, Rhizoma Et Radix Notopterygii, withered stalk, Herba Schizonepetae, Folium Perillae, Radix Bupleuri, Radix Saposhnikoviae, Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, the Radix Rehmanniae, Rhizoma Atractylodis, Bulbus Fritillariae Cirrhosae, Cortex Fraxini, Pheretima, Herba Houttuyniae, Herba Asari, Radix Glycyrrhizae, Flos Lonicerae are extracted medicinal liquid in ultrasonic assistant ethanol extraction FAXIA, the condition extracted is: solid-liquid ratio is 1:8-16, ultrasonic power is 120-180W, concentration of alcohol is 50%-80%, Extracting temperature is 40-70 DEG C, and extraction time is 30-90min;
S12: by extraction medical filtration obtained for step S11, be condensed into paste;
S13: dried by paste obtained for step S12, pulverize, sieve, sterilizing, obtains described Chinese medicine preparation.
Preferably, extracting concentration of liquid medicine in step S12 becomes paste to relative density to be 1.1-1.3.
Preferably, the condition of drying in step S13 is: dry to water content≤6% at 90-105 DEG C.
Preferably, the condition of sieving in step S13 is: cross 200-400 object sieve.
Preferably, in step S13, the condition of sterilizing is: temperature is 134-136 DEG C, and pressure is 210-230KPa, and the time is 4-6min.
Chinese medicine preparation pharmacology of the present invention is as follows:
Pericarpium Citri Reticulatae has effect such as ventilation spleen invigorating, drying dampness to eliminate phlegm, the greasy lasting of solution, stopping nausea and vomiting by lowering the adverse flow of QI etc., can cure cold, generate heat, distension and fullness of the chest and abdomen, anorexia, vomiting hiccup, the symptom such as cough with copious phlegm.
Radix Puerariae has expelling pathogenic factors from muscles for reducing heat, deliver examine, the effect such as promoting the production of body fluid to quench thirst, yang invigorating antidiarrheal, fever caused by exogenous pathogens can be controlled, rigidity pain on the head and nape, measles go out the symptoms such as smooth, epidemic febrile disease is thirsty, diabetes from the beginning of, rash.
Ramulus Cinnamomi has expelling cold and relieving exterior syndrome, help heart-yang and, the effect such as resolving fluid-retention with drugs of warm nature, the symptoms such as anemofrigid cold, harmonizing yingfen and weifen, expelling pathogenic factors from muscles hidroschesis can be controlled.
Rhizoma Et Radix Notopterygii has the effect such as expelling pathogenic wind from the body surface, removing dampness pain relieving, cures mainly the diseases such as the heating of cold, aversion to cold, headache, rheumatic arthralgia.
The effects such as withered stalk has lung qi dispersing, sore-throat relieving, eliminates the phlegm, evacuation of pus, cure mainly the diseases such as cough with copious phlegm, laryngopharynx swelling and pain, lung abscess vomiting pus, fullness in the chest and hypochondriac pain, dysentery stomachache, uroschesis.
The effects such as Herba Schizonepetae has dispeling the wind, induces sweat, rash, hemostasis, can cure cold, generate heat, have a headache, eye itching, cough, the disease such as laryngopharynx swelling and pain.
Folium Perillae has effect such as cold expelling, relieving QI stagnancy in the stomach of inducing sweat, and can control anemofrigid cold, disease such as cough vomiting and nausea, vomiting during pregnancy etc.
Radix Bupleuri have induce sweat bring down a fever, the effect such as dispersing the stagnated live-QI to relieve the stagnation of QI, elevate a turnable ladder yang-energy, the diseases such as fever caused by exogenous pathogens, alternate attack of chill and fever, malaria, hypochondriac pain due to stagnation of liverQI, mammary swelling, headache dizziness can be controlled.
Radix Saposhnikoviae has the effects such as expelling pathogenic wind from the body surface, removing damp and stopping pain, soothing the liver spasmolytic, cures mainly the diseases such as affection of exogenous wind-cold, headache stiffness of the nape, dizzy dusk puckery, anemofrigid-damp arthralgia.
Rhizoma Chuanxiong has the effect such as blood-activating and qi-promoting, wind-expelling pain-stopping, can control headache, rheumatic arthralgia, menoxenia, amenorrhea dysmenorrhea, lump in the abdomen stomachache, disease such as the breast side of body twinge, tumbling and swelling etc.
The effects such as the Radix Angelicae Dahuricae has wind-damp dispelling, evacuation of pus of invigorating blood circulation, granulation promoting pain relieving, can control the diseases such as headache, toothache, nasal sinusitis, hemorrhoidal hamorrhage anal fistula, leucorrhea with red and white discharge, ulcer sores, skin pruritus.
The Radix Rehmanniae has the effects such as heat clearing and blood cooling, enriching yin and nourishing kidney, promoting the production of body fluid to quench thirst, can control the diseases such as hectic fever due to YIN-deficiency consumptive disease heat, throat pain, sputum mixed with blood.
Rhizoma Atractylodis have expelling wind and removing dampness, the effect such as drying damp and strengthening spleen, can control that seasonal epidemic pathogens is caught a cold, vomits, had loose bowels, the symptom such as dysentery, malaria, phlegm retention, edema, anemofrigid-damp arthralgia, flaccidity of the lower limbs.
Bulbus Fritillariae Cirrhosae has the effects such as nourishing the lung to arrest cough, can cure cold, the symptom such as acute tracheitis, bronchitis, pulmonary tuberculosis.
Cortex Fraxini has the effects such as heat clearing and damp drying, liver heat removing and eyesight improving, antiasthmatic-antitussive, can cure cold, the symptom such as acute bronchitis, pneumonia.
Pheretima has the effects such as heat clearing away, suppressing the hyperactive liver, Zhichuan, dredging collateral, cures mainly the symptoms such as high heat agitation, infantile convulsion tic, dyspnea and cough due to lung-heat, accumulation of heat urine retention.
Herba Houttuyniae has the effect such as heat-clearing and toxic substances removing, inducing diuresis to remove edema, can cure cold, pneumonia, lung abscess, hematodiarrhoea, malaria, edema, gonorrhea, the symptom such as leucorrhea.
Herba Asari have dispel the wind, the effect such as cold expelling, the symptoms such as air-cooled headache, nasal sinusitis, toothache, phlegm retention cough with dyspnea, rheumatic arthralgia can be controlled.
Radix Glycyrrhizae has removing toxic substances, eliminates the phlegm, pain relieving, spasmolytic, the effect such as anticancer, can cure cold, have a fever, cough, cardio palmus shape.
Flos Lonicerae has the effect such as heat-clearing and toxic substances removing, dispelling wind and heat pathogens, cures mainly red and swollen heat pain, affection due to external wind and heat, epidemic febrile disease from the beginning of, the symptom such as toxic-heat and blood stasis, summer-heat excessive thirst, laryngopharynx swelling and pain.
The present invention has following beneficial effect:
(1) the present invention combines Pericarpium Citri Reticulatae, Radix Puerariae, Ramulus Cinnamomi, Rhizoma Et Radix Notopterygii, withered stalk, Herba Schizonepetae, Folium Perillae, Radix Bupleuri, Radix Saposhnikoviae, Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, the Radix Rehmanniae, Rhizoma Atractylodis, Bulbus Fritillariae Cirrhosae, Cortex Fraxini, Pheretima, Herba Houttuyniae, Herba Asari, Radix Glycyrrhizae, Flos Lonicerae plurality of Chinese effect, heat-clearing and toxic substances removing can be played, suppress acute inflammation, eliminate the phlegm, the effect such as antibacterial, antiviral, the onset of this tablet treatment flu is rapid, evident in efficacy, and drug effect safety and stability, cure rate are high, without any side effects;
(2) tablet of the present invention carries out sterilizing at high temperature under high pressure, and the time is short, effective, the holding time is long;
(3) tablet manufacturing method of the present invention is simple to operate, and production cost is low, is conducive to applying.
[detailed description of the invention]
Be specifically described below in conjunction with specific embodiment.
Embodiment 1
A kind of tablet for the treatment of flu, in units of weight portion, comprise following raw material: starch 500 parts, 200 parts, Gypsum Fibrosum, 100 parts, crystal sugar, Mel 100 parts, magnesium stearate 100 parts, Chinese medicine preparation 200 parts, described Chinese medicine preparation comprises following raw material: Pericarpium Citri Reticulatae 16 parts, Radix Puerariae 16 parts, Ramulus Cinnamomi 16 parts, Rhizoma Et Radix Notopterygii 16 parts, 16 parts, withered stalk, Herba Schizonepetae 12 parts, Folium Perillae 12 parts, Radix Bupleuri 12 parts, Radix Saposhnikoviae 12 parts, Rhizoma Chuanxiong 12 parts, the Radix Angelicae Dahuricae 8 parts, 8 parts, the Radix Rehmanniae, Rhizoma Atractylodis 8 parts, Bulbus Fritillariae Cirrhosae 8 parts, Cortex Fraxini 8 parts, Pheretima 4 parts, Herba Houttuyniae 4 parts, Herba Asari 4 parts, 4 parts, Radix Glycyrrhizae, Flos Lonicerae 4 parts.
The preparation method of the tablet of described treatment flu, comprises the following steps:
S1, crude product are produced: the starch of described ratio, Gypsum Fibrosum, crystal sugar, Mel, magnesium stearate, Chinese medicine preparation mixing, add 200 parts of water and make lamellar after stirring, the tablet crude product of obtained treatment flu;
S2, oven dry, sterilizing: it is 6% that the tablet crude product that the treatment that step S1 obtains is caught a cold is dried to water content at temperature is 80 DEG C, and be 210KPa at pressure, temperature is 134 DEG C, and the time is under 8min after sterilizing, the tablet of obtained treatment flu.
The preparation method of above-mentioned Chinese medicine preparation, comprises the following steps:
S11: Pericarpium Citri Reticulatae, Radix Puerariae, Ramulus Cinnamomi, Rhizoma Et Radix Notopterygii, withered stalk, Herba Schizonepetae, Folium Perillae, Radix Bupleuri, Radix Saposhnikoviae, Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, the Radix Rehmanniae, Rhizoma Atractylodis, Bulbus Fritillariae Cirrhosae, Cortex Fraxini, Pheretima, Herba Houttuyniae, Herba Asari, Radix Glycyrrhizae, Flos Lonicerae are extracted medicinal liquid in ultrasonic assistant ethanol extraction FAXIA, the condition extracted is: solid-liquid ratio is 1:8, ultrasonic power is 120W, concentration of alcohol is 50%, Extracting temperature is 40 DEG C, and extraction time is 90min;
S12: by extraction medical filtration obtained for step S11, to be condensed into paste to relative density be 1.1;
S13: drying to water content at 90 DEG C by paste obtained for step S12 is 6%, crosses 200 object sieves after pulverizing, be finally 134 DEG C the powder of the gained that sieves in temperature, pressure is 210KPa, and the time is sterilizing under 6min, obtained Chinese medicine preparation.
Embodiment 2
A kind of tablet for the treatment of flu, in units of weight portion, comprise following raw material: starch 1500 parts, 600 parts, Gypsum Fibrosum, 300 parts, crystal sugar, Mel 300 parts, magnesium stearate 300 parts, Chinese medicine preparation 400 parts, described Chinese medicine preparation comprises following raw material: Pericarpium Citri Reticulatae 32 parts, Radix Puerariae 32 parts, Ramulus Cinnamomi 32 parts, Rhizoma Et Radix Notopterygii 32 parts, 32 parts, withered stalk, Herba Schizonepetae 24 parts, Folium Perillae 24 parts, Radix Bupleuri 24 parts, Radix Saposhnikoviae 24 parts, Rhizoma Chuanxiong 24 parts, the Radix Angelicae Dahuricae 16 parts, 16 parts, the Radix Rehmanniae, Rhizoma Atractylodis 16 parts, Bulbus Fritillariae Cirrhosae 16 parts, Cortex Fraxini 16 parts, Pheretima 8 parts, Herba Houttuyniae 8 parts, Herba Asari 8 parts, 8 parts, Radix Glycyrrhizae, Flos Lonicerae 8 parts.
The preparation method of the tablet of described treatment flu, comprises the following steps:
S1, crude product are produced: the starch of described ratio, Gypsum Fibrosum, crystal sugar, Mel, magnesium stearate, Chinese medicine preparation mixing, add 1000 parts of water and make lamellar after stirring, the tablet crude product of obtained treatment flu;
S2, oven dry, sterilizing: it is 5% that the tablet crude product that the treatment that step S1 obtains is caught a cold is dried to water content at temperature is 100 DEG C, and be 230KPa at pressure, temperature is 136 DEG C, and the time is under 6min after sterilizing, the tablet of obtained treatment flu.
The preparation method of above-mentioned Chinese medicine preparation, comprises the following steps:
S11: Pericarpium Citri Reticulatae, Radix Puerariae, Ramulus Cinnamomi, Rhizoma Et Radix Notopterygii, withered stalk, Herba Schizonepetae, Folium Perillae, Radix Bupleuri, Radix Saposhnikoviae, Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, the Radix Rehmanniae, Rhizoma Atractylodis, Bulbus Fritillariae Cirrhosae, Cortex Fraxini, Pheretima, Herba Houttuyniae, Herba Asari, Radix Glycyrrhizae, Flos Lonicerae are extracted medicinal liquid in ultrasonic assistant ethanol extraction FAXIA, the condition extracted is: solid-liquid ratio is 1:16, ultrasonic power is 180W, concentration of alcohol is 80%, Extracting temperature is 70 DEG C, and extraction time is 50min;
S12: by extraction medical filtration obtained for step S11, to be condensed into paste to relative density be 1.3;
S13: drying to water content at 100 DEG C by paste obtained for step S12 is 5%, crosses 400 object sieves after pulverizing, be finally 135 DEG C the powder of the gained that sieves in temperature, pressure is 220KPa, and the time is sterilizing under 5min, obtained Chinese medicine preparation
Embodiment 3
A kind of tablet for the treatment of flu, in units of weight portion, comprise following raw material: starch 1000 parts, 400 parts, Gypsum Fibrosum, 200 parts, crystal sugar, Mel 200 parts, magnesium stearate 200 parts, Chinese medicine preparation 300 parts, described Chinese medicine preparation comprises following raw material: Pericarpium Citri Reticulatae 24 parts, Radix Puerariae 24 parts, Ramulus Cinnamomi 24 parts, Rhizoma Et Radix Notopterygii 24 parts, 24 parts, withered stalk, Herba Schizonepetae 18 parts, Folium Perillae 18 parts, Radix Bupleuri 18 parts, Radix Saposhnikoviae 18 parts, Rhizoma Chuanxiong 18 parts, the Radix Angelicae Dahuricae 12 parts, 12 parts, the Radix Rehmanniae, Rhizoma Atractylodis 12 parts, Bulbus Fritillariae Cirrhosae 12 parts, Cortex Fraxini 12 parts, Pheretima 6 parts, Herba Houttuyniae 6 parts, Herba Asari 6 parts, 6 parts, Radix Glycyrrhizae, Flos Lonicerae 6 parts.
The preparation method of the tablet of described treatment flu, comprises the following steps:
S1, crude product are produced: the starch of described ratio, Gypsum Fibrosum, crystal sugar, Mel, magnesium stearate, Chinese medicine preparation mixing, add 600 parts of water and make lamellar after stirring, the tablet crude product of obtained treatment flu;
S2, oven dry, sterilizing: it is 4% that the tablet crude product that the treatment that step S1 obtains is caught a cold is dried to water content at temperature is 90 DEG C, and be 220KPa at pressure, temperature is 135 DEG C, and the time is under 7min after sterilizing, the tablet of obtained treatment flu.
The preparation method of above-mentioned Chinese medicine preparation, comprises the following steps:
S11: Pericarpium Citri Reticulatae, Radix Puerariae, Ramulus Cinnamomi, Rhizoma Et Radix Notopterygii, withered stalk, Herba Schizonepetae, Folium Perillae, Radix Bupleuri, Radix Saposhnikoviae, Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, the Radix Rehmanniae, Rhizoma Atractylodis, Bulbus Fritillariae Cirrhosae, Cortex Fraxini, Pheretima, Herba Houttuyniae, Herba Asari, Radix Glycyrrhizae, Flos Lonicerae are extracted medicinal liquid in ultrasonic assistant ethanol extraction FAXIA, the condition extracted is: solid-liquid ratio is 1:12, ultrasonic power is 160W, concentration of alcohol is 60%, Extracting temperature is 50 DEG C, and extraction time is 30min;
S12: by extraction medical filtration obtained for step S11, to be condensed into paste to relative density be 1.2;
S13: drying to water content at 105 DEG C by paste obtained for step S12 is 4%, crosses 300 object sieves after pulverizing, be finally 136 DEG C the powder of the gained that sieves in temperature, pressure is 30KPa, and the time is sterilizing under 4min, obtained Chinese medicine preparation.
Embodiment 4
A kind of tablet for the treatment of flu, in units of weight portion, comprise following raw material: starch 700 parts, 300 parts, Gypsum Fibrosum, 150 parts, crystal sugar, Mel 150 parts, magnesium stearate 150 parts, Chinese medicine preparation 250 parts, described Chinese medicine preparation comprises following raw material: Pericarpium Citri Reticulatae 20 parts, Radix Puerariae 20 parts, Ramulus Cinnamomi 20 parts, Rhizoma Et Radix Notopterygii 20 parts, 20 parts, withered stalk, Herba Schizonepetae 15 parts, Folium Perillae 15 parts, Radix Bupleuri 15 parts, Radix Saposhnikoviae 15 parts, Rhizoma Chuanxiong 15 parts, the Radix Angelicae Dahuricae 10 parts, 10 parts, the Radix Rehmanniae, Rhizoma Atractylodis 10 parts, Bulbus Fritillariae Cirrhosae 10 parts, Cortex Fraxini 10 parts, Pheretima 5 parts, Herba Houttuyniae 5 parts, Herba Asari 5 parts, 5 parts, Radix Glycyrrhizae, Flos Lonicerae 5 parts.
The preparation method of the tablet of described treatment flu, comprises the following steps:
S1, crude product are produced: the starch of described ratio, Gypsum Fibrosum, crystal sugar, Mel, magnesium stearate, Chinese medicine preparation mixing, add 500 parts of water and make lamellar after stirring, the tablet crude product of obtained treatment flu;
S2, oven dry, sterilizing: it is 6% that the tablet crude product that the treatment that step S1 obtains is caught a cold is dried to water content at temperature is 80 DEG C, and be 210KPa at pressure, temperature is 134 DEG C, and the time is under 8min after sterilizing, the tablet of obtained treatment flu.
The preparation method of above-mentioned Chinese medicine preparation, comprises the following steps:
S11: Pericarpium Citri Reticulatae, Radix Puerariae, Ramulus Cinnamomi, Rhizoma Et Radix Notopterygii, withered stalk, Herba Schizonepetae, Folium Perillae, Radix Bupleuri, Radix Saposhnikoviae, Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, the Radix Rehmanniae, Rhizoma Atractylodis, Bulbus Fritillariae Cirrhosae, Cortex Fraxini, Pheretima, Herba Houttuyniae, Herba Asari, Radix Glycyrrhizae, Flos Lonicerae are extracted medicinal liquid in ultrasonic assistant ethanol extraction FAXIA, the condition extracted is: solid-liquid ratio is 1:10, ultrasonic power is 140W, concentration of alcohol is 70%, Extracting temperature is 60 DEG C, and extraction time is 70min;
S12: by extraction medical filtration obtained for step S11, to be condensed into paste to relative density be 1.1;
S13: drying to water content at 95 DEG C by paste obtained for step S12 is 6%, crosses 200 object sieves after pulverizing, be finally 134 DEG C the powder of the gained that sieves in temperature, pressure is 210KPa, and the time is sterilizing under 6min, obtained Chinese medicine preparation.
Embodiment 5
A kind of tablet for the treatment of flu, in units of weight portion, comprise following raw material: starch 1300 parts, 500 parts, Gypsum Fibrosum, 250 parts, crystal sugar, Mel 250 parts, magnesium stearate 250 parts, Chinese medicine preparation 350 parts, described Chinese medicine preparation comprises following raw material: Pericarpium Citri Reticulatae 28 parts, Radix Puerariae 28 parts, Ramulus Cinnamomi 28 parts, Rhizoma Et Radix Notopterygii 28 parts, 28 parts, withered stalk, Herba Schizonepetae 21 parts, Folium Perillae 21 parts, Radix Bupleuri 21 parts, Radix Saposhnikoviae 21 parts, Rhizoma Chuanxiong 21 parts, the Radix Angelicae Dahuricae 14 parts, 14 parts, the Radix Rehmanniae, Rhizoma Atractylodis 14 parts, Bulbus Fritillariae Cirrhosae 14 parts, Cortex Fraxini 14 parts, Pheretima 7 parts, Herba Houttuyniae 7 parts, Herba Asari 7 parts, 7 parts, Radix Glycyrrhizae, Flos Lonicerae 7 parts.
The preparation method of the tablet of described treatment flu, comprises the following steps:
S1, crude product are produced: the starch of described ratio, Gypsum Fibrosum, crystal sugar, Mel, magnesium stearate, Chinese medicine preparation mixing, add 800 parts of water and make lamellar after stirring, the tablet crude product of obtained treatment flu;
S2, oven dry, sterilizing: it is 5% that the tablet crude product that the treatment that step S1 obtains is caught a cold is dried to water content at temperature is 100 DEG C, and be 230KPa at pressure, temperature is 136 DEG C, and the time is under 6min after sterilizing, the tablet of obtained treatment flu.
The preparation method of above-mentioned Chinese medicine preparation, comprises the following steps:
S11: Pericarpium Citri Reticulatae, Radix Puerariae, Ramulus Cinnamomi, Rhizoma Et Radix Notopterygii, withered stalk, Herba Schizonepetae, Folium Perillae, Radix Bupleuri, Radix Saposhnikoviae, Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, the Radix Rehmanniae, Rhizoma Atractylodis, Bulbus Fritillariae Cirrhosae, Cortex Fraxini, Pheretima, Herba Houttuyniae, Herba Asari, Radix Glycyrrhizae, Flos Lonicerae are extracted medicinal liquid in ultrasonic assistant ethanol extraction FAXIA, the condition extracted is: solid-liquid ratio is 1:14, ultrasonic power is 150W, concentration of alcohol is 50%, Extracting temperature is 60 DEG C, and extraction time is 60min;
S12: by extraction medical filtration obtained for step S11, to be condensed into paste to relative density be 1.3;
S13: drying to water content at 105 DEG C by paste obtained for step S12 is 5%, crosses 400 object sieves after pulverizing, be finally 136 DEG C the powder of the gained that sieves in temperature, pressure is 230KPa, and the time is sterilizing under 4min, obtained Chinese medicine preparation.
As follows through clinical test results: treatment cold patients 108 example, male 57 example, women 51 example, the age be 10-80 year, usage is: the tablet taking embodiment 3, every day three times, be 1-3 sheet g, consumption takes the circumstances into consideration to add and subtract dosage according to the concrete condition of patient at every turn, it within two days, is a course for the treatment of, take observe the curative effect after two courses for the treatment of, recovery from illness 92 example, accounts for 85.19%; Effective 7 examples, account for 6.48%; Take a turn for the better 6 examples, accounts for 5.56%; Invalid 3 examples, account for 2.78%; Total effective rate reaches 97.22%, and after two course of therapy, the shapes such as patient's nasal obstruction, heating, watery nasal discharge, headache all have clear improvement or fully recover, and patient is without any untoward reaction.
Above content can not assert that the present invention specifically implements to be confined to these explanations; for general technical staff of the technical field of the invention; do not departing under concept thereof of the present invention; some simple deduction or replace can also be made, all should be considered as belonging to the scope of patent protection that the present invention is determined by submitted to claims.
Claims (10)
1. treat the tablet of flu for one kind, it is characterized in that, in units of weight portion, comprise following raw material: starch 500-1500 part, Gypsum Fibrosum 200-600 part, crystal sugar 100-300 part, Mel 100-300 part, magnesium stearate 100-300 part, Chinese medicine preparation 200-400 part, described Chinese medicine preparation comprises following raw material: Pericarpium Citri Reticulatae 16-32 part, Radix Puerariae 16-32 part, Ramulus Cinnamomi 16-32 part, Rhizoma Et Radix Notopterygii 16-32 part, withered stalk 16-32 part, Herba Schizonepetae 12-24 part, Folium Perillae 12-24 part, Radix Bupleuri 12-24 part, Radix Saposhnikoviae 12-24 part, Rhizoma Chuanxiong 12-24 part, Radix Angelicae Dahuricae 8-16 part, Radix Rehmanniae 8-16 part, Rhizoma Atractylodis 8-16 part, Bulbus Fritillariae Cirrhosae 8-16 part, Cortex Fraxini 8-16 part, Pheretima 4-8 part, Herba Houttuyniae 4-8 part, Herba Asari 4-8 part, Radix Glycyrrhizae 4-8 part, Flos Lonicerae 4-8 part.
2. the tablet for the treatment of flu according to claim 1, it is characterized in that, in units of weight portion, comprise following raw material: starch 700-1300 part, Gypsum Fibrosum 300-500 part, crystal sugar 150-250 part, Mel 150-250 part, magnesium stearate 150-250 part, Chinese medicine preparation 250-350 part, described Chinese medicine preparation comprises following raw material: Pericarpium Citri Reticulatae 20-28 part, Radix Puerariae 20-28 part, Ramulus Cinnamomi 20-28 part, Rhizoma Et Radix Notopterygii 20-28 part, withered stalk 20-28 part, Herba Schizonepetae 15-21 part, Folium Perillae 15-21 part, Radix Bupleuri 15-21 part, Radix Saposhnikoviae 15-21 part, Rhizoma Chuanxiong 15-21 part, Radix Angelicae Dahuricae 10-14 part, Radix Rehmanniae 10-14 part, Rhizoma Atractylodis 10-14 part, Bulbus Fritillariae Cirrhosae 10-14 part, Cortex Fraxini 10-14 part, Pheretima 5-7 part, Herba Houttuyniae 5-7 part, Herba Asari 5-7 part, Radix Glycyrrhizae 5-7 part, Flos Lonicerae 5-7 part.
3. the tablet for the treatment of flu according to claim 2, it is characterized in that, in units of weight portion, comprise following raw material: starch 1000 parts, 400 parts, Gypsum Fibrosum, 200 parts, crystal sugar, Mel 200 parts, magnesium stearate 200 parts, Chinese medicine preparation 300 parts, described Chinese medicine preparation comprises following raw material: Pericarpium Citri Reticulatae 24 parts, Radix Puerariae 24 parts, Ramulus Cinnamomi 24 parts, Rhizoma Et Radix Notopterygii 24 parts, 24 parts, withered stalk, Herba Schizonepetae 18 parts, Folium Perillae 18 parts, Radix Bupleuri 18 parts, Radix Saposhnikoviae 18 parts, Rhizoma Chuanxiong 18 parts, the Radix Angelicae Dahuricae 12 parts, 12 parts, the Radix Rehmanniae, Rhizoma Atractylodis 12 parts, Bulbus Fritillariae Cirrhosae 12 parts, Cortex Fraxini 12 parts, Pheretima 6 parts, Herba Houttuyniae 6 parts, Herba Asari 6 parts, 6 parts, Radix Glycyrrhizae, Flos Lonicerae 6 parts.
4. the preparation method of the tablet of the treatment flu according to any one of claim 1-3, is characterized in that, comprise the following steps:
S1, crude product are produced: the starch of described ratio, Gypsum Fibrosum, crystal sugar, Mel, magnesium stearate, Chinese medicine preparation mixing, add 200-1000 part water and make lamellar after stirring, the tablet crude product of obtained treatment flu;
S2, oven dry, sterilizing: the tablet crude product of the treatment flu that step S1 is obtained is dried, after sterilizing, the tablet of obtained treatment flu.
5. the preparation method of the tablet for the treatment of flu according to claim 4, it is characterized in that, the temperature of drying in step S2 is 80-100 DEG C, dry to water content≤6%, the pressure of sterilizing is 210-230KPa, and the temperature of sterilizing is 134-136 DEG C, and the time of sterilizing is 6-8min.
6. the preparation method of the tablet for the treatment of flu according to claim 4, it is characterized in that, the preparation method of Chinese medicine preparation described in step S1 comprises the following steps:
S11: Pericarpium Citri Reticulatae, Radix Puerariae, Ramulus Cinnamomi, Rhizoma Et Radix Notopterygii, withered stalk, Herba Schizonepetae, Folium Perillae, Radix Bupleuri, Radix Saposhnikoviae, Rhizoma Chuanxiong, the Radix Angelicae Dahuricae, the Radix Rehmanniae, Rhizoma Atractylodis, Bulbus Fritillariae Cirrhosae, Cortex Fraxini, Pheretima, Herba Houttuyniae, Herba Asari, Radix Glycyrrhizae, Flos Lonicerae are extracted medicinal liquid in ultrasonic assistant ethanol extraction FAXIA, the condition extracted is: solid-liquid ratio is 1:8-16, ultrasonic power is 120-180W, concentration of alcohol is 50%-80%, Extracting temperature is 40-70 DEG C, and extraction time is 30-90min;
S12: by extraction medical filtration obtained for step S11, be condensed into paste;
S13: dried by paste obtained for step S12, pulverize, sieve, sterilizing, obtains described Chinese medicine preparation.
7. the preparation method of the tablet for the treatment of flu according to claim 6, is characterized in that, extract concentration of liquid medicine and become paste to relative density to be 1.1-1.3 in step S12.
8. the preparation method of the tablet for the treatment of flu according to claim 6, it is characterized in that, the condition of drying in step S13 is: dry to water content≤6% at 90-105 DEG C.
9. the preparation method of the tablet for the treatment of flu according to claim 6, it is characterized in that, the condition of sieving in step S13 is: cross 200-400 object sieve.
10. the preparation method of the tablet for the treatment of flu according to claim 6, it is characterized in that, in step S13, the condition of sterilizing is: temperature is 134-136 DEG C, and pressure is 210-230KPa, and the time is 4-6min.
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107823613A (en) * | 2017-12-07 | 2018-03-23 | 白石磊 | A kind of external application body lotion |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20070005950A (en) * | 2005-07-05 | 2007-01-11 | 이인경 | Method for preparing of mushroom culture material fortified gamma-aminobutyric acid |
| CN101254255A (en) * | 2008-04-11 | 2008-09-03 | 刘宗升 | Traditional Chinese medicine preparation for curing cold |
| CN102614286A (en) * | 2012-04-25 | 2012-08-01 | 平阴县孔村卫生院 | Medicine for treating cold and preparation method for medicine |
-
2015
- 2015-08-07 CN CN201510481971.7A patent/CN105031193A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20070005950A (en) * | 2005-07-05 | 2007-01-11 | 이인경 | Method for preparing of mushroom culture material fortified gamma-aminobutyric acid |
| CN101254255A (en) * | 2008-04-11 | 2008-09-03 | 刘宗升 | Traditional Chinese medicine preparation for curing cold |
| CN102614286A (en) * | 2012-04-25 | 2012-08-01 | 平阴县孔村卫生院 | Medicine for treating cold and preparation method for medicine |
Non-Patent Citations (1)
| Title |
|---|
| 窦志强: "荆防败毒散加减治疗甲型H1N1流感8例", 《中医药信息》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107823613A (en) * | 2017-12-07 | 2018-03-23 | 白石磊 | A kind of external application body lotion |
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