CN105017679A - Preparation method of polyvinyl chloride material used for medical bronchial catheters - Google Patents
Preparation method of polyvinyl chloride material used for medical bronchial catheters Download PDFInfo
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- CN105017679A CN105017679A CN201510370698.0A CN201510370698A CN105017679A CN 105017679 A CN105017679 A CN 105017679A CN 201510370698 A CN201510370698 A CN 201510370698A CN 105017679 A CN105017679 A CN 105017679A
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Abstract
The invention discloses a preparation method of a polyvinyl chloride material used for medical bronchial catheters. The preparation method comprises following steps: step 1, by weight, ingredients are delivered into a high speed mixer for 20 to 40min of stirring and mixing; and step 2, an obtained uniformly mixed material is delivered into a double-screw extruder for fusion, plasticizing, extrusion, and pelleting so as to obtain the polyvinyl chloride material. Preparation method flow is relatively short; operation is simple; cost is low; the preparation method is friendly to the environment, and is high in economic benefits. Compared with the prior art, the polyvinyl chloride material used for medical bronchial catheters possesses excellent biocompatibility and safety, and performance better than that of related products on the market.
Description
Technical field
The invention belongs to polymeric material field, relate to a kind of preparation method of medical bronchial catheter pvc material.
Technical background
Plastics, as a kind of very important material, are widely applied at medicine and hygiene fields.It both can be made into disposable medical instrument as dropping bottle, syringe etc., can be used for again non-once medical facilities as gauger, surgery instrument etc., and medical plastic field is current plastics industry one of market having development potentiality most.
Along with the sustainable growth of population in the world quantity, particularly aging populations and the increase of number suffering from chronic disease, facilitate the sustainable growth of medical services market, special medical apparatus obtains widespread demand.Due to macromolecular material excellent specific property and also can reduce costs, at present, medical treatment product and apparatus are from large-scale diagnostic instrments, disposable medical article so that meticulous artificial organ all be unable to do without macromolecular material, and macromolecular material becomes one of important raw and processed materials of medical treatment product and apparatus gradually.And at present, in respiratory system field, the plastics relevant to respirator are that plastics apply one of the most concentrated field in medicine equipment, bronchial catheter uses one of maximum plastics in medical instruments field, and these goods are mostly prepared from by materials such as polyethylene, polyvinyl chloride, polypropylene, rubber.The product of this class is the easily-consumed products that quantity is larger, and China consumes the value of this series products every year at about several hundred million yuans, and market is very huge.Current China can autonomous production respirator and associated plastic goods thereof, but due to factors such as product finenesses, product is mainly used in small and medium-sized cities and vast Rural areas or outlet, and mainly apply as metropolitan markets such as Beijing-Tianjin Shanghai or external imported product, therefore the market space is still very large.Due to contact with liquid or and human contact, the basic demand of medical grade plastic materials has chemical stability and biological safety.In simple terms, the moiety in plastic material can not be separated out and enter liquid or human body, can not cause toxicity and the damage of histoorgan, is nontoxic to human body.For improving blood compatibility, the histocompatibility of goods, need the modifying surface to goods.The plastic tool anti-infection property of interposing catheter and life-time service is also one of research and development direction of current medical grade plastic materials.In sum, a kind of property separated out is low, security is high medical bronchial catheter plastic material is badly in need of providing to be this area technical problem urgently to be resolved hurrily.
Summary of the invention
The object of the invention is to for the deficiencies in the prior art, a kind of preparation method of medical bronchial catheter pvc material is provided.
The object of the invention is to be achieved through the following technical solutions: a kind of preparation method of medical bronchial catheter pvc material, said method comprising the steps of: the 1st step, by weight, by polyvinyl chloride 60-70 part, polyamide resin is 8-18 part, ethylene-octene copolymer 40-50 part, tripoly phosphate sodium STPP 3-8 part, two maleinamic acid 6-12 part, 2-thiol group benzimidazolyl 4-11 part, ethene-α-ethylene-octene copolymer 11-16 part, diacetone alcohol 4-11 part, alumina-silicate ceramic fibre 11-21 part, Glacial acetic acid 3-8 part, nucleator 2.5-4.5 part, antiseptic-germicide 2-4 part, toughner 5-12 part, stearic acid 4-8 part and calcium carbonate 2-4 part are dropped in homogenizer, be uniformly mixed 20 ~ 40 minutes, 2nd step, the material mixed joined melting in twin screw extruder, plastify, extrude, granulation, to obtain final product.Described extrusion temperature is 140 ~ 160 DEG C.Described nucleator is (3,4-dimethyl two benzal) sorbyl alcohol or methylene-bis (2,4-di-tert-butyl-phenyl) phosphoric acid ester oxyaluminum salt.
Described toughner is grafting maleic anhydride with ethylene propylene terpolymer.
Described antiseptic-germicide is nano silver inorganic antimicrobial agent or primary ammonium phosphate.
The present invention has following beneficial effect: preparation method's flow process of the present invention is shorter, simple to operate, and cost is low, environmentally friendly, high financial profit.Compared with prior art, the medical bronchial catheter pvc material that the method for the invention provides is prepared has excellent biocompatibility and security, be all better than the performance of existing related products on the market, and its intensity is high, good mechanical property.
Embodiment
embodiment 1
A kind of preparation method of medical bronchial catheter pvc material, said method comprising the steps of: the 1st step, by weight, by polyvinyl chloride 60 parts, polyamide resin is 8 parts, ethylene-octene copolymer 40 parts, tripoly phosphate sodium STPP 3 parts, two maleinamic acid 6 parts, 2-thiol group benzimidazolyl 4 parts, ethene-α-ethylene-octene copolymer 11 parts, diacetone alcohol 4 parts, alumina-silicate ceramic fibre 11 parts, 3 parts, Glacial acetic acid, nucleator 2.5 parts, antiseptic-germicide 2 parts, toughner 5 parts, stearic acid 4 parts is with in calcium carbonate 2 parts of input homogenizers, be uniformly mixed 20 ~ 40 minutes, 2nd step, the material mixed joined melting in twin screw extruder, plastify, extrude, granulation, to obtain final product.Described extrusion temperature is 140 ~ 160 DEG C.Described nucleator is (3,4-dimethyl two benzal) sorbyl alcohol or methylene-bis (2,4-di-tert-butyl-phenyl) phosphoric acid ester oxyaluminum salt.
Described toughner is grafting maleic anhydride with ethylene propylene terpolymer.
Described antiseptic-germicide is nano silver inorganic antimicrobial agent or primary ammonium phosphate.
embodiment 2
A kind of preparation method of medical bronchial catheter pvc material, said method comprising the steps of: the 1st step, by weight, by polyvinyl chloride 70 parts, polyamide resin is 18 parts, ethylene-octene copolymer 50 parts, tripoly phosphate sodium STPP 8 parts, two maleinamic acid 12 parts, 2-thiol group benzimidazolyl 11 parts, ethene-α-ethylene-octene copolymer 16 parts, diacetone alcohol 11 parts, alumina-silicate ceramic fibre 21 parts, 8 parts, Glacial acetic acid, nucleator 4.5 parts, antiseptic-germicide 4 parts, toughner 12 parts, stearic acid 8 parts is with in calcium carbonate 4 parts of input homogenizers, be uniformly mixed 20 ~ 40 minutes, 2nd step, the material mixed joined melting in twin screw extruder, plastify, extrude, granulation, to obtain final product.Described extrusion temperature is 140 ~ 160 DEG C.Described nucleator is (3,4-dimethyl two benzal) sorbyl alcohol or methylene-bis (2,4-di-tert-butyl-phenyl) phosphoric acid ester oxyaluminum salt.
Described toughner is grafting maleic anhydride with ethylene propylene terpolymer.
Described antiseptic-germicide is nano silver inorganic antimicrobial agent or primary ammonium phosphate.
embodiment 3
A kind of preparation method of medical bronchial catheter pvc material, said method comprising the steps of: the 1st step, by weight, by polyvinyl chloride 65 parts, polyamide resin is 12 parts, ethylene-octene copolymer 45 parts, tripoly phosphate sodium STPP 6 parts, two maleinamic acid 8 parts, 2-thiol group benzimidazolyl 8 parts, ethene-α-ethylene-octene copolymer 13 parts, diacetone alcohol 7 parts, alumina-silicate ceramic fibre 17 parts, 6 parts, Glacial acetic acid, nucleator 4 parts, antiseptic-germicide 3 parts, toughner 8 parts, stearic acid 6 parts is with in calcium carbonate 3 parts of input homogenizers, be uniformly mixed 20 ~ 40 minutes, 2nd step, the material mixed joined melting in twin screw extruder, plastify, extrude, granulation, to obtain final product.Described extrusion temperature is 140 ~ 160 DEG C.Described nucleator is (3,4-dimethyl two benzal) sorbyl alcohol or methylene-bis (2,4-di-tert-butyl-phenyl) phosphoric acid ester oxyaluminum salt.
Described toughner is grafting maleic anhydride with ethylene propylene terpolymer.
Described antiseptic-germicide is nano silver inorganic antimicrobial agent or primary ammonium phosphate.
The above, it is only preferred embodiment of the present invention, not any pro forma restriction is done to the present invention, although the present invention discloses as above with preferred embodiment, but and be not used to limit the present invention, any those skilled in the art, do not departing within the scope of technical solution of the present invention, make a little change when the technology contents of above-mentioned announcement can be utilized or be modified to the Equivalent embodiments of equivalent variations, in every case be the content not departing from technical solution of the present invention, according to any simple modification that technical spirit of the present invention is done above embodiment, equivalent variations and modification, all still belong in the scope of technical solution of the present invention.
Claims (5)
1. the preparation method of a medical bronchial catheter pvc material, it is characterized in that, said method comprising the steps of: the 1st step, by weight, by polyvinyl chloride 60-70 part, polyamide resin is 8-18 part, ethylene-octene copolymer 40-50 part, tripoly phosphate sodium STPP 3-8 part, two maleinamic acid 6-12 part, 2-thiol group benzimidazolyl 4-11 part, ethene-α-ethylene-octene copolymer 11-16 part, diacetone alcohol 4-11 part, alumina-silicate ceramic fibre 11-21 part, Glacial acetic acid 3-8 part, nucleator 2.5-4.5 part, antiseptic-germicide 2-4 part, toughner 5-12 part, stearic acid 4-8 part and calcium carbonate 2-4 part are dropped in homogenizer, be uniformly mixed 20 ~ 40 minutes, 2nd step, the material mixed joined melting in twin screw extruder, plastify, extrude, granulation, to obtain final product.
2. the preparation method of a kind of medical bronchial catheter pvc material according to claim 1, it is characterized in that, described extrusion temperature is 140 ~ 160 DEG C.
3. the preparation method of a kind of medical bronchial catheter pvc material according to claim 1, it is characterized in that, described nucleator is (3,4-dimethyl two benzal) sorbyl alcohol or methylene-bis (2,4-di-tert-butyl-phenyl) phosphoric acid ester oxyaluminum salt.
4. the preparation method of a kind of medical bronchial catheter pvc material according to claim 1, it is characterized in that, described toughner is grafting maleic anhydride with ethylene propylene terpolymer.
5. the preparation method of a kind of medical bronchial catheter pvc material according to claim 1, it is characterized in that, described antiseptic-germicide is nano silver inorganic antimicrobial agent or primary ammonium phosphate.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510370698.0A CN105017679A (en) | 2015-06-30 | 2015-06-30 | Preparation method of polyvinyl chloride material used for medical bronchial catheters |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510370698.0A CN105017679A (en) | 2015-06-30 | 2015-06-30 | Preparation method of polyvinyl chloride material used for medical bronchial catheters |
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| CN105017679A true CN105017679A (en) | 2015-11-04 |
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| CN201510370698.0A Pending CN105017679A (en) | 2015-06-30 | 2015-06-30 | Preparation method of polyvinyl chloride material used for medical bronchial catheters |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106147084A (en) * | 2016-08-24 | 2016-11-23 | 安徽顺彤包装材料有限公司 | A kind of antibacterial medical packaging material and preparation method thereof |
| CN106280342A (en) * | 2016-08-30 | 2017-01-04 | 胡何辉 | A kind of PP composite material being applicable to medical infusion bags and preparation method thereof |
| CN113292787A (en) * | 2021-05-08 | 2021-08-24 | 华南理工大学 | Beta crystal form nucleating agent and preparation method and application thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104356536A (en) * | 2014-10-24 | 2015-02-18 | 苏州蔻美新材料有限公司 | Medical antibacterial hose and preparation method thereof |
| CN104371214A (en) * | 2014-10-28 | 2015-02-25 | 昆山艾士比高分子科技有限公司 | Antibacterial medical material |
| CN104371222A (en) * | 2014-11-07 | 2015-02-25 | 苏州维泰生物技术有限公司 | Medical composite antimicrobial tube and preparation method thereof |
| CN104725736A (en) * | 2013-12-23 | 2015-06-24 | 刘泽华 | Medical perfusion tube material |
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2015
- 2015-06-30 CN CN201510370698.0A patent/CN105017679A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104725736A (en) * | 2013-12-23 | 2015-06-24 | 刘泽华 | Medical perfusion tube material |
| CN104356536A (en) * | 2014-10-24 | 2015-02-18 | 苏州蔻美新材料有限公司 | Medical antibacterial hose and preparation method thereof |
| CN104371214A (en) * | 2014-10-28 | 2015-02-25 | 昆山艾士比高分子科技有限公司 | Antibacterial medical material |
| CN104371222A (en) * | 2014-11-07 | 2015-02-25 | 苏州维泰生物技术有限公司 | Medical composite antimicrobial tube and preparation method thereof |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106147084A (en) * | 2016-08-24 | 2016-11-23 | 安徽顺彤包装材料有限公司 | A kind of antibacterial medical packaging material and preparation method thereof |
| CN106280342A (en) * | 2016-08-30 | 2017-01-04 | 胡何辉 | A kind of PP composite material being applicable to medical infusion bags and preparation method thereof |
| CN113292787A (en) * | 2021-05-08 | 2021-08-24 | 华南理工大学 | Beta crystal form nucleating agent and preparation method and application thereof |
| CN113292787B (en) * | 2021-05-08 | 2022-04-08 | 华南理工大学 | Beta crystal form nucleating agent and preparation method and application thereof |
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Application publication date: 20151104 |
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