CN105153535A - Preparation method of medical tracheal intubation polypropylene material - Google Patents

Preparation method of medical tracheal intubation polypropylene material Download PDF

Info

Publication number
CN105153535A
CN105153535A CN201510370936.8A CN201510370936A CN105153535A CN 105153535 A CN105153535 A CN 105153535A CN 201510370936 A CN201510370936 A CN 201510370936A CN 105153535 A CN105153535 A CN 105153535A
Authority
CN
China
Prior art keywords
parts
preparation
polypropylene material
mixing
medical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201510370936.8A
Other languages
Chinese (zh)
Inventor
吕少波
李卓才
李苏杨
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Suzhou Jonathan New Materials Technology Co Ltd
Original Assignee
Suzhou Jonathan New Materials Technology Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suzhou Jonathan New Materials Technology Co Ltd filed Critical Suzhou Jonathan New Materials Technology Co Ltd
Priority to CN201510370936.8A priority Critical patent/CN105153535A/en
Publication of CN105153535A publication Critical patent/CN105153535A/en
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L23/00Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers
    • C08L23/02Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers not modified by chemical after-treatment
    • C08L23/10Homopolymers or copolymers of propene
    • C08L23/12Polypropene
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08KUse of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K2201/00Specific properties of additives
    • C08K2201/011Nanostructured additives
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2203/00Applications
    • C08L2203/02Applications for biomedical use
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2203/00Applications
    • C08L2203/18Applications used for pipes
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2205/00Polymer mixtures characterised by other features
    • C08L2205/02Polymer mixtures characterised by other features containing two or more polymers of the same C08L -group
    • C08L2205/025Polymer mixtures characterised by other features containing two or more polymers of the same C08L -group containing two or more polymers of the same hierarchy C08L, and differing only in parameters such as density, comonomer content, molecular weight, structure
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2205/00Polymer mixtures characterised by other features
    • C08L2205/03Polymer mixtures characterised by other features containing three or more polymers in a blend
    • C08L2205/035Polymer mixtures characterised by other features containing three or more polymers in a blend containing four or more polymers in a blend

Abstract

The invention discloses a preparation method of a medical tracheal intubation polypropylene material. The method includes the steps of: 1. adding all components into a mixer according to weight part, mixing the materials evenly to obtain a main material; 2. adding assistants into the main material obtained in step 1, and mixing the substances evenly to obtain a mixture; 3. adding the mixture obtained in step 2 into a double-screw extruder, mixing the substances evenly, and performing melt extrusion so as to obtain a strip blend; and 4. cooling, dicing and splitting the strip blend obtained in step 3, thus obtaining the medical tracheal intubation polypropylene material. The preparation method provided by the invention has the advantages of short process, simple operation, low cost, environmental friendliness and high economic benefits. Compared with the prior art, the medical tracheal intubation polypropylene material prepared by the method provided by the invention has excellent biocompatibility and safety superior to the performance of related products existing on the market.

Description

A kind of preparation method of Medical trachea cannula polypropylene material
Technical field
The invention belongs to polymeric material field, relate to a kind of preparation method of Medical trachea cannula polypropylene material.
Technical background
Plastics, as a kind of very important material, are widely applied at medicine and hygiene fields.It both can be made into disposable medical instrument as dropping bottle, syringe etc., can be used for again non-once medical facilities as gauger, surgery instrument etc., and medical plastic field is current plastics industry one of market having development potentiality most.
Along with the sustainable growth of population in the world quantity, particularly aging populations and the increase of number suffering from chronic disease, facilitate the sustainable growth of medical services market, special medical apparatus obtains widespread demand.Due to macromolecular material excellent specific property and also can reduce costs, at present, medical treatment product and apparatus are from large-scale diagnostic instrments, disposable medical article so that meticulous artificial organ all be unable to do without macromolecular material, and macromolecular material becomes one of important raw and processed materials of medical treatment product and apparatus gradually.And at present, in respiratory system field, the plastics relevant to respirator are one of fields that plastic applications is the most concentrated in medicine equipment, trachea cannula uses one of maximum plastics in medical instruments field, and these goods are mostly prepared from by materials such as polyethylene, polyvinyl chloride, polypropylene, rubber.Trachea cannula refers to that the technology by a special endotracheal tube inserts tracheae through glottis is called trachea cannula, and this technology can attract for airway patency, ventilation oxygen-supplying, respiratory tract and prevent from inhaling etc. by mistake provide top condition.Emergency trachea intubation technique has become cardiopulmonary resuscitation and with the important measures in the Severe acute disease patient rescue process of respiratory dysfunction.Endotracheal intubation is important rescue technology conventional in rescue service, most widely used general, the most effective one of means the most efficiently in management of respiratory, be the basic skills that medical worker must skillfully grasp, vital effect is played to rescue patient vitals, reduction case fatality rate.And can the tracheal strips secretory product of sucking-off in time or foreign matter, prevent foreign matter from entering respiratory tract, keep respiratory passage unblocked, carry out effective artificial or mechanical ventilation, in time whether direct relation that the success of rescuing becomes no, can patient the prognosis situation of safe transit and patient to prevent patient's anoxic and carbon dioxide retention trachea cannula.The product of this class is the easily-consumed products that quantity is larger, and China consumes the value of this series products every year at about several hundred million yuans, and market is very huge.Current China can autonomous production respirator and associated plastic goods thereof, but due to factors such as product finenesses, product is mainly used in small and medium-sized cities and vast Rural areas or outlet, and mainly apply as metropolitan markets such as Beijing-Tianjin Shanghai or external imported product, therefore the market space is still very large.Due to contact with liquid or and human contact, the basic demand of medical grade plastic materials has chemical stability and biological safety.In simple terms, the moiety in plastic material can not be separated out and enter liquid or human body, can not cause toxicity and the damage of histoorgan, is nontoxic to human body.For improving blood compatibility, the histocompatibility of goods, need the modifying surface to goods.The plastic tool anti-infection property of interposing catheter and life-time service is also one of research and development direction of current medical grade plastic materials.In sum, a kind of property separated out is low, security is high Medical trachea cannula plastic material is badly in need of providing to be this area technical problem urgently to be resolved hurrily.
Summary of the invention
The object of the invention is to for the deficiencies in the prior art, a kind of preparation method of Medical trachea cannula polypropylene material is provided.
The object of the invention is to be achieved through the following technical solutions: a kind of preparation method of Medical trachea cannula polypropylene material, said method comprising the steps of: the 1st step, by weight, by polypropylene 80-90 part, ethylene-propylene rubber(EPR) 14-20 part, polyvinylpyrrolidone 2-5 part, silicon rubber 30-40 part, tributyl citrate 2-6 part, magnesium borate crystal whisker 2-7 part, ethene-α-ethylene-octene copolymer 5-8 part, stearic acid 4-8 part, divinyl tetramine 2-6 part, toughner 3-8 part, dispersion agent 5-20 part, light calcium carbonate 12-20 part, antiseptic-germicide is 2-6 part, primary ammonium phosphate is 2-5 part, HACC is 2-5 part, polyvinyl chloride is 25-36 part, diethyl phthalate is 2-6 part, clorafin is 2-5 part and polyamide resin is that 8-18 part adds in mixer, major ingredient is obtained after mixing,
2nd step, in the 1st step gained major ingredient, add antiseptic-germicide 7-9 part, toughner 6-8 part and dispersion agent 6-9 part, after mixing, obtain mixture; 3rd step, add in twin screw extruder by the 2nd step gained mixture, screw speed is 400-450r/min, after mixing, melt extrudes and obtains strip blend; 4th step, by the 3rd step gained strip blend cooling after pelletizing split, to obtain final product.
Described extrusion temperature is 260-300 DEG C.
Described antiseptic-germicide is nano silver inorganic antimicrobial agent or primary ammonium phosphate.
Described toughner is grafting maleic anhydride with ethylene propylene terpolymer.
Described dispersion agent is the one in polyethylene wax, oxidized polyethlene wax, polyamide wax.
The present invention has following beneficial effect: preparation method's flow process of the present invention is shorter, simple to operate, and cost is low, environmentally friendly, high financial profit.Compared with prior art, the Medical trachea cannula polypropylene material that the method for the invention provides is prepared has excellent biocompatibility and security, be all better than the performance of existing related products on the market, and its intensity is high, good mechanical property.
Embodiment
embodiment 1
A kind of preparation method of Medical trachea cannula polypropylene material, said method comprising the steps of: the 1st step, by weight, by polypropylene 80 parts, 14 parts, ethylene-propylene rubber(EPR), polyvinylpyrrolidone 2 parts, 30 parts, silicon rubber, tributyl citrate 2 parts, magnesium borate crystal whisker 2 parts, ethene-α-ethylene-octene copolymer 5 parts, stearic acid 4 parts, divinyl tetramine 2 parts, toughner 3 parts, dispersion agent 5 parts, light calcium carbonate 12 parts, antiseptic-germicide is 2 parts, primary ammonium phosphate is 2 parts, HACC is 2 parts, polyvinyl chloride is 25 parts, diethyl phthalate is 2 parts, clorafin is that 2 parts and polyamide resin are 8 parts and add in mixer, major ingredient is obtained after mixing,
2nd step, in the 1st step gained major ingredient, add antiseptic-germicide 7 parts, toughner 6 parts and dispersion agent 6 parts, after mixing, obtain mixture; 3rd step, add in twin screw extruder by the 2nd step gained mixture, screw speed is 400-450r/min, after mixing, melt extrudes and obtains strip blend; 4th step, by the 3rd step gained strip blend cooling after pelletizing split, to obtain final product.
Described extrusion temperature is 260-300 DEG C.
Described antiseptic-germicide is nano silver inorganic antimicrobial agent or primary ammonium phosphate.
Described toughner is grafting maleic anhydride with ethylene propylene terpolymer.
Described dispersion agent is the one in polyethylene wax, oxidized polyethlene wax, polyamide wax.
embodiment 2
A kind of preparation method of Medical trachea cannula polypropylene material, said method comprising the steps of: the 1st step, by weight, by polypropylene 90 parts, 20 parts, ethylene-propylene rubber(EPR), polyvinylpyrrolidone 5 parts, 40 parts, silicon rubber, tributyl citrate 6 parts, magnesium borate crystal whisker 7 parts, ethene-α-ethylene-octene copolymer 8 parts, stearic acid 8 parts, divinyl tetramine 6 parts, toughner 8 parts, dispersion agent 20 parts, light calcium carbonate 20 parts, antiseptic-germicide is 6 parts, primary ammonium phosphate is 5 parts, HACC is 5 parts, polyvinyl chloride is 36 parts, diethyl phthalate is 6 parts, clorafin is that 5 parts and polyamide resin are 18 parts and add in mixer, major ingredient is obtained after mixing,
2nd step, in the 1st step gained major ingredient, add antiseptic-germicide 9 parts, toughner 8 parts and dispersion agent 9 parts, after mixing, obtain mixture; 3rd step, add in twin screw extruder by the 2nd step gained mixture, screw speed is 400-450r/min, after mixing, melt extrudes and obtains strip blend; 4th step, by the 3rd step gained strip blend cooling after pelletizing split, to obtain final product.
Described extrusion temperature is 260-300 DEG C.
Described antiseptic-germicide is nano silver inorganic antimicrobial agent or primary ammonium phosphate.
Described toughner is grafting maleic anhydride with ethylene propylene terpolymer.
Described dispersion agent is the one in polyethylene wax, oxidized polyethlene wax, polyamide wax.
embodiment 3
A kind of preparation method of Medical trachea cannula polypropylene material, said method comprising the steps of: the 1st step, by weight, by polypropylene 85 parts, 18 parts, ethylene-propylene rubber(EPR), polyvinylpyrrolidone 4 parts, 35 parts, silicon rubber, tributyl citrate 4 parts, magnesium borate crystal whisker 5 parts, ethene-α-ethylene-octene copolymer 6 parts, stearic acid 6 parts, divinyl tetramine 4 parts, toughner 6 parts, dispersion agent 16 parts, light calcium carbonate 15 parts, antiseptic-germicide is 5 parts, primary ammonium phosphate is 4 parts, HACC is 4 parts, polyvinyl chloride is 29 parts, diethyl phthalate is 4 parts, clorafin is that 4 parts and polyamide resin are 13 parts and add in mixer, major ingredient is obtained after mixing,
2nd step, in the 1st step gained major ingredient, add antiseptic-germicide 8 parts, toughner 7 parts and dispersion agent 7 parts, after mixing, obtain mixture; 3rd step, add in twin screw extruder by the 2nd step gained mixture, screw speed is 400-450r/min, after mixing, melt extrudes and obtains strip blend; 4th step, by the 3rd step gained strip blend cooling after pelletizing split, to obtain final product.
Described extrusion temperature is 260-300 DEG C.
Described antiseptic-germicide is nano silver inorganic antimicrobial agent or primary ammonium phosphate.
Described toughner is grafting maleic anhydride with ethylene propylene terpolymer.
Described dispersion agent is the one in polyethylene wax, oxidized polyethlene wax, polyamide wax.
The above, it is only preferred embodiment of the present invention, not any pro forma restriction is done to the present invention, although the present invention discloses as above with preferred embodiment, but and be not used to limit the present invention, any those skilled in the art, do not departing within the scope of technical solution of the present invention, make a little change when the technology contents of above-mentioned announcement can be utilized or be modified to the Equivalent embodiments of equivalent variations, in every case be the content not departing from technical solution of the present invention, according to any simple modification that technical spirit of the present invention is done above embodiment, equivalent variations and modification, all still belong in the scope of technical solution of the present invention.

Claims (5)

1. the preparation method of a Medical trachea cannula polypropylene material, it is characterized in that, said method comprising the steps of: the 1st step, by weight, by polypropylene 80-90 part, ethylene-propylene rubber(EPR) 14-20 part, polyvinylpyrrolidone 2-5 part, silicon rubber 30-40 part, tributyl citrate 2-6 part, magnesium borate crystal whisker 2-7 part, ethene-α-ethylene-octene copolymer 5-8 part, stearic acid 4-8 part, divinyl tetramine 2-6 part, toughner 3-8 part, dispersion agent 5-20 part, light calcium carbonate 12-20 part, antiseptic-germicide is 2-6 part, primary ammonium phosphate is 2-5 part, HACC is 2-5 part, polyvinyl chloride is 25-36 part, diethyl phthalate is 2-6 part, clorafin is 2-5 part and polyamide resin is that 8-18 part adds in mixer, major ingredient is obtained after mixing,
2nd step, in the 1st step gained major ingredient, add antiseptic-germicide 7-9 part, toughner 6-8 part and dispersion agent 6-9 part, after mixing, obtain mixture; 3rd step, add in twin screw extruder by the 2nd step gained mixture, screw speed is 400-450r/min, after mixing, melt extrudes and obtains strip blend; 4th step, by the 3rd step gained strip blend cooling after pelletizing split, to obtain final product.
2. the preparation method of a kind of Medical trachea cannula polypropylene material according to claim 1, is characterized in that, described extrusion temperature is 260-300 DEG C.
3. the preparation method of a kind of Medical trachea cannula polypropylene material according to claim 1, is characterized in that, described antiseptic-germicide is nano silver inorganic antimicrobial agent or primary ammonium phosphate.
4. the preparation method of a kind of Medical trachea cannula polypropylene material according to claim 1, it is characterized in that, described toughner is grafting maleic anhydride with ethylene propylene terpolymer.
5. the preparation method of a kind of Medical trachea cannula polypropylene material according to claim 1, is characterized in that, described dispersion agent is the one in polyethylene wax, oxidized polyethlene wax, polyamide wax.
CN201510370936.8A 2015-06-30 2015-06-30 Preparation method of medical tracheal intubation polypropylene material Pending CN105153535A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201510370936.8A CN105153535A (en) 2015-06-30 2015-06-30 Preparation method of medical tracheal intubation polypropylene material

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201510370936.8A CN105153535A (en) 2015-06-30 2015-06-30 Preparation method of medical tracheal intubation polypropylene material

Publications (1)

Publication Number Publication Date
CN105153535A true CN105153535A (en) 2015-12-16

Family

ID=54794605

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201510370936.8A Pending CN105153535A (en) 2015-06-30 2015-06-30 Preparation method of medical tracheal intubation polypropylene material

Country Status (1)

Country Link
CN (1) CN105153535A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106188907A (en) * 2016-08-30 2016-12-07 何仁英 A kind of biological material being applicable to flexible pipe for medical purpose and preparation method thereof
CN107434877A (en) * 2017-07-07 2017-12-05 闫盛 A kind of sheath tube material and preparation method thereof
CN108285581A (en) * 2018-03-02 2018-07-17 付主枝 A kind of preparation method and applications of medical polypropylene composite material

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106188907A (en) * 2016-08-30 2016-12-07 何仁英 A kind of biological material being applicable to flexible pipe for medical purpose and preparation method thereof
CN107434877A (en) * 2017-07-07 2017-12-05 闫盛 A kind of sheath tube material and preparation method thereof
CN108285581A (en) * 2018-03-02 2018-07-17 付主枝 A kind of preparation method and applications of medical polypropylene composite material

Similar Documents

Publication Publication Date Title
CN104961969A (en) Method for preparing polypropylene material for medical bronchial catheter
CN105017680A (en) Preparation method of polyvinyl chloride material used for medical trachea cannulas
CN105153535A (en) Preparation method of medical tracheal intubation polypropylene material
CN103554624B (en) The preparation method of antibacterial polyvinyl resin
CN105218964B (en) Antibacterial polyvinyl chloride material and its preparation method and application
CN106366426B (en) A kind of platelet rich plasma extraction and the separation gel system purified and preparation method thereof
CN104961955A (en) Method for preparing polyethylene material for medical trachea cannula
CN101361991A (en) Slowly released type antibiotic medical catheter and preparation method thereof
CN107501803A (en) A kind of trachea cannula pvc material and preparation method thereof
CN104941006A (en) Preparation method of composite material for joint prosthesis
US20210162159A1 (en) Scent infused nasal cannula and methods of use and fabrication thereof
CN104961958A (en) Preparation method of polyethylene material for artificial joint
CN104962002A (en) Preparation method for polyvinyl chloride material for medical mask
CN105017679A (en) Preparation method of polyvinyl chloride material used for medical bronchial catheters
CN104448618A (en) Composite material for medical plastic products and preparation method thereof
CN105175849A (en) Plastic packaging material for injection powder and preparation process thereof
CN105153534A (en) Preparation method for polypropylene material used for medical mask
CN106751556A (en) A kind of ventilative membrane material
CN104961956A (en) Preparation method for polyethylene material for medical mask
CN104961954A (en) Method for preparing polyethylene material for medical bronchial catheter
CN109735042A (en) A kind of medical AMTPS material, medical instrument and preparation method
CN105131472A (en) Preparation method of anti-fogging medical film having sterilizing function
CN104974489A (en) Preparation method for polyglycolic acid material used for artificial nerve conduit
CN106398009A (en) Anti-corrosion antibacterial medical rubber and preparation method thereof
DE69531249T2 (en) Hoses made of polyetherester modified with ionomer for the transport of medical and similar liquids

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20151216

RJ01 Rejection of invention patent application after publication