CN104971280A - Foot bath powder for treating dermatophytosis and preparation method thereof - Google Patents
Foot bath powder for treating dermatophytosis and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a foot bath powder for treating dermatophytosis. The foot bath powder is prepared from the following medicinal raw materials in parts by weight: 9-15 parts of Sessile Stemona root, 7-14 parts of jewelweed, 10-16 parts of Actinostemma lobatum, 12-18 parts of lalang grass rhizome, 9-17 parts of garden balsam stem, 11-16 parts of Twin-sorus Fern, 8-15 parts of dried watercress, 9-16 parts of towel gourd juice, 7-13 parts of pyrolusite, 10-13 parts of nakedflower beautyberry branchlet and leaf, 8-12 parts of citron, 9-13 parts of broomcorn millet stalk, 11-15 parts of Garden Erphorbia Herb and 9-12 parts of fenugreek. The foot bath powder disclosed by the invention has the beneficial effects that the used materials are all traditional Chinese medicine materials, the curative effect is outstanding, no side effect can be generated, and the foot bah powder is simple in preparation and is economical and convenient; the traditional Chinese medicine raw materials effectively achieve the effects of clearing away heat, removing dampness, removing toxicity and destroying intestinal worms through dialectic compatibility of medicines, the active ingredients are stable, the effect is long-lasting and the shelf life is long.
Description
Technical field
The present invention relates to traditional Chinese medicine field.Particularly relate to a kind of lavipeditum powder and method for making thereof for the treatment of beriberi.
Background technology
Beriberi, formal name used at school tinea pedis is that fungal infection causes, and its skin lesion is first one-sided (i.e. single foot) generation often, just infects to offside after several weeks or several months.Vesicle mainly appears at toe abdomen and toe side, and be most commonly between three or four toes, vola also can occur, for dark in property phlysis, can be fused into bulla gradually.The skin lesion of tinea pedis has a feature, i.e. clear border, can gradually to external expansion.Because of PD or scratch, erosion, sepage can be there is, even bacteriological infection, occur pustule etc.In China, the sickness rate of tinea pedis is also quite high.Do not have sebaceous gland between the vola of people and toe, thus lack the fatty acid suppressing skin filamentous fungi, physiological defense function is poor, and the sweat gland of skin at these positions is very abundant, perspire many, poor, the locally damp warm of air circulation, is conducive to the growth of filamentous fungi in addition.In addition, vola area skin horny layer is thicker, and the keratin in horny layer is the abundant nutrition material of fungus, is conducive to the growth of fungus.The morbidity of tinea pedis is also relevant with living habit.Some people does not note the situation of foot sanitation and hygiene and footgear, for fungus provides good breeding site.
Beriberi is a kind of common multiple diseases, is to cause due to various fungal infection.According to clinical manifestation, beriberi is broadly divided into vesicle, erosive type and squama keratinization type three types.1. vesicle: mostly occur in summer, symptom is between toe, sufficient edge, vola occur grain of rice size deeply in property vesicle, and evacuate or distribute in groups, bleb wall is thicker, and content is thorough clearly, not easily breaks.Dry desquamation after a few days, mutually merges and forms kerionic vesicle, tear bleb wall off, visible honeycomb substrate and the rotten to the corn face of cerise, violent pruritus.2. erosive type: show as local horny layer of epidermis and macerate and turn white.Constantly rub during owing to walking about exfoliation, exposes the rotten to the corn face of cerise; Between severe patient toe seam, toe abdomen and vola intersection skin all can involve, acute pruritus, is mainly between 3,4,5 toes stitch, is common in hyperhidrosis person.3. squama keratinization type: symptom is vola, sufficient edge, heel portion skin keratin thicken, coarse, desquamation, and squama slabbing or little point-like, come off repeatedly.Winter toe seam between skin occur crack, summer produces vesicle, has pain.Chang Yin scratches and causes secondary infection, the illness such as concurrent pustule ulcer, lymphangitis, lymphadenitis, cellulitis, erysipelas, septicemia.Clinical diagnosis is easier to, and it is more difficult to effect a radical cure.
Application publication number CN104644836A(application number 201310602890.9) Chinese invention patent document disclose a kind of athlete foot powder being used for the treatment of beriberi, be made up of following weight parts raw material: Radix Sophorae Flavescentis 20-30; Cortex Dictamni 20-30; Herba Portulacae 15-20; Herba Plantaginis 15-20; Cortex Phellodendri 10-15; Rhizoma Atractylodis 10-15; Spice 0.01-0.02.Application publication number CN104474368A(application number 201410699907.1) Chinese invention patent document disclose a kind of medicine for the treatment of beriberi, be made up of the raw material of following weight parts: Radix Scutellariae 10-15, Radix Arnebiae (Radix Lithospermi) 8-12, Fructus Forsythiae 8-12, Semen Coicis 12-18, Flos Lonicerae 10-15, Flos Gardeniae 6-12, Radix Angelicae Sinensis 10-15, dried Alumen 6-12, Calomelas 6-12; Radix Scutellariae 8-12, Radix Angelicae Dahuricae 8-12, Radix Rehmanniae 8-12, Rhizoma Coptidis 10-15, Radix Angelicae Sinensis 10-15, Radix Sophorae Flavescentis 6-12, Herba Houttuyniae 6-10, dried Alumen 10-15, Calomelas 10-15, Adeps sus domestica 120-180.Application publication number CN102908395A(application number 201110221293.2) Chinese invention patent document disclose a kind of athlete foot powder, be made up of following raw material: Gypsum Fibrosum 5-20, Alumen 10-20, Radix Glycyrrhizae 10-20, Flos Caryophylli 5-15, Radix Angelicae Dahuricae 5-15, Pulvis Talci 5-8, sofril 2-4, Margarita powder 1-3.
Current Western medicine is with Drug therapys such as antibiotics, and effect is undesirable, can only relief of symptoms, and namely drug withdrawal recurs, and does not reach radical cure object.The clinical effectiveness of Chinese medicine or prescription is all undesirable, or function singleness, or effect slowly.
Summary of the invention
For the deficiencies in the prior art, the object of the present invention is to provide a kind of lavipeditum powder and method for making for the treatment of beriberi, adopt medical material comparatively common in the localities as raw material, with low cost.Medicine can go directly patient part by the present invention, effectively ensures curative effect, reaches the object for the treatment of both the principal and secondary aspects of a disease, and more after also not easily recur, there is therapeutic effect good, have no side effect, the advantage that treatment cost is low.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
Treat a lavipeditum powder for beriberi, be prepared from by following bulk drugs, be weight portion: Radix Stemonae 9-15; Flos seu Radix Impatientis nolitangeris 7-14; Herba Actinstemmatis Lobati 10-16; Rhizoma Imperatae 12-18; Herba speranskiae tuberculatae 9-17; Diplazium lanceum (Thunb) 11-16; Herba Nasturth officinalis 8-15; It Luo Shui 9-16; Pyrolusitum 7-13; Folium et Ramulus Callicarpae nudiflorae 10-13; Fructus Citri 8-12; Caulis Panici miliacei 9-13; Herba Euphoubiae Hirtae 11-15; Semen Trigonellae 9-12.
In preferred scheme, Radix Stemonae 10.5-13.5; Flos seu Radix Impatientis nolitangeris 9-12; Herba Actinstemmatis Lobati 12-14; Rhizoma Imperatae 14-16; Herba speranskiae tuberculatae 11-15; Diplazium lanceum (Thunb) 12.5-14.5; Herba Nasturth officinalis 10-13; It Luo Shui 11-14; Pyrolusitum 9-11; Folium et Ramulus Callicarpae nudiflorae 11-12; Fructus Citri 9-11; Caulis Panici miliacei 10-12; Herba Euphoubiae Hirtae 12-14; Semen Trigonellae 10-11.
Be more preferably, the Radix Stemonae 12; Flos seu Radix Impatientis nolitangeris 10.5; Herba Actinstemmatis Lobati 13; Rhizoma Imperatae 15; Herba speranskiae tuberculatae 13; Diplazium lanceum (Thunb) 13.5; Herba Nasturth officinalis 11.5; It Luo Shui 12.5; Pyrolusitum 10; Folium et Ramulus Callicarpae nudiflorae 11.5; Fructus Citri 10; Caulis Panici miliacei 11; Herba Euphoubiae Hirtae 13; Semen Trigonellae 10.5.
Treat a preparation method for the lavipeditum powder of beriberi, step is as follows:
(1) Semen Trigonellae is eluriated clean with clear water, first be placed in Chinese liquor to soak 10-16 hour (be preferably placed in Chinese liquor and soak 12-14 hour), taking-up is dried, and then turns in steamer, slow fire heating is steamed to well-done, finally be placed in parch container, slow fire heats, and fries extremely to making sound, in yellow, taking-up cools, and is ground into fine powder, for subsequent use; Pyrolusitum is placed in charcoal fire, and intense fire is forged red, is placed in rice vinegar cancellation, and repeat 3-7 time (preferably repeating 4-6 time), cooling, porphyrize powder is for subsequent use;
(2) Flos seu Radix Impatientis nolitangeris, Herba Actinstemmatis Lobati, Fructus Citri, Folium et Ramulus Callicarpae nudiflorae and Caulis Panici miliacei are placed in traditional Chinese medicine drying machine, in 55-65 DEG C of dry 25-45 minute (being preferable over 58-62 DEG C of dry 30-40 minute), then adjust the temperature to 40-50 DEG C of dry 1-3 hour (preferably adjusting the temperature to 43-47 DEG C of dry 1.5-2.5 hour), slightly cool, be placed in pulverizer and be ground into fine powder, for subsequent use;
(3) by the Radix Stemonae, Rhizoma Imperatae, Herba speranskiae tuberculatae, Diplazium lanceum (Thunb), Herba Nasturth officinalis and Herba Euphoubiae Hirtae are placed in medicine pot, add cold water to powder 3-5cm, intense fire heated and boiled, turn slow fire boiling three times, first time decocts 42-54 minute (preferably first time decocts 46-50 minute), second time and third time decoct 22-40 minute (preferably second time and third time decoct 26-36 minute respectively) respectively, merge three decocting liquids, filter, Tian Luoshui is added in filtrate, mixing, be evaporated to paste, be cooled to room temperature, ethanol is added in thick paste, leave standstill, filter, distilling under reduced pressure is extremely without alcohol taste, vacuum drying gets dry extract, let cool, porphyrize, for subsequent use,
(4) by step (1)-(3) process after raw material medicated powder mixing, sieve, dry heat sterilization 35-55 minute (preferred dry heat sterilization 40-50 minute), according to 20-30g/ bag metering (preferably according to the metering of 23-27g/ bag) subpackage and get final product.
Above-mentioned a kind of preparation method for the treatment of the lavipeditum powder of beriberi, preferred scheme is, in step (1), the number of degrees of Chinese liquor are 42 °-65 ° (number of degrees of preferred Chinese liquor are 45 °-60 °, and the number of degrees of the Chinese liquor be more preferably are 55 °).
Above-mentioned a kind of preparation method for the treatment of the lavipeditum powder of beriberi, preferred scheme is, in step (3), the mass concentration of ethanol is the mass concentration of the preferred ethanol of 70%-90%(is 75%-85%, and the mass concentration of the ethanol be more preferably is 80%).
Above-mentioned a kind of preparation method for the treatment of the lavipeditum powder of beriberi, preferred scheme is, in step (3), the mass ratio of ethanol and thick paste is the mass ratio of the preferred ethanol of 1:2-4(and thick paste is 1:2.5-3.5, and the ethanol be more preferably and the mass ratio of thick paste are 1:3).
Above-mentioned a kind of preparation method for the treatment of the lavipeditum powder of beriberi, preferred scheme is, leaves standstill 22-30 hour (preferred standing 24-28 hour, what be more preferably leaves standstill 26 hours) in step (3).
Above-mentioned a kind of preparation method for the treatment of the lavipeditum powder of beriberi, preferred scheme is, the middle 55-95 mesh sieve excessively of step (4) (preferred 65-85 mesh sieve excessively, mistake 75 mesh sieve be more preferably).
Above-mentioned a kind of preparation method for the treatment of the lavipeditum powder of beriberi, preferred scheme is, in step (4), the temperature of dry heat sterilization is 78-96 DEG C (temperature of preferred dry heat sterilization is 82-92 DEG C, and the temperature of the dry heat sterilization be more preferably is 87 DEG C).
The pharmacological effect of each crude drug is respectively:
The Radix Stemonae: base is former: be the tuber of Stemonaceae plant Radix stemonae japonicae, Radix Stemonae or radix stemonae tuberosae etc.Pharmacological action: 1. antibacterial action: during in vitro tests the Radix Stemonae (kind is not identified) decoct and the immersion of radix stemonae tuberosae ethanol to various pathogens as streptococcus pneumoniae, beta hemolysis type streptococcus, meningococcus, staphylococcus aureus, Staphylococcus albus and dysentery bacterium, Bacillus typhi, Salmonella paratyphi, escherichia coli, Bacillus proteus, diphtheria corynebacterium, pneumobacillus, bacillus pestis, anthrax bacillus, bacillus subtilis, and vibrio cholera, Bacillus tuberculosis etc. have bacteriostasis in various degree; 2. insecticidal action: the infusion of Radix stemonae japonicae and other kind of Radix Stemonae (kind is not identified) and ethanol immersion, all has killing action to mosquitos and flies larva, head louse, clothing louse and Cimex bedbug etc.The high concentration Radix Stemonae (kind fail to understand) in vitro and can kill Mus pinworm.Nature and flavor: sweetness and bitterness, tepor.Gui Jing: enter lung meridian.Function cures mainly: gentle lung qi, cough-relieving, parasite killing.Control cough due to wind and cold, pertussis, pulmonary tuberculosis, old cough with asthma, ascarid, enterobiasis, skin scabies, eczema.
Flos seu Radix Impatientis nolitangeris: base is former: be flower or the root of Balsaminaceae plant Flos seu Radix Impatientis nolitangeris.Chemical analysis: flower is containing neoxathin and taraxanthin, and the latter proves a mixture by analysis, interior based on phylloxanthin epoxide, separately has butterfly prunus mume (sieb.) sieb.et zucc. xanthin, Herba Ranunculi Japonici xanthin chrysanthemaxanthin and corpus luteum furan element.Nature and flavor: sweet in the mouth; Warm in nature.Function cures mainly: promoting blood flow to regulate menstruation; Apparent wind dehumidifies.Main menoxenia; Dysmenorrhea; Amenorrhea; Traumatic injury; Rheumatic arthralgia; Beriberi swells and ache; Eczema scrotum; Tinea skin ulcer; Impetigo.
Herba Actinstemmatis Lobati: base is former: be leaf or the seed of cucurbitaceous plant Herba Actinstemmatis Lobati.Chemical analysis: seed fatty oily 25 ~ 29%, carbohydrate 13.28%, ash 2.95%, crude fibre 0.89%.Fatty oil is semi-drying, wherein containing solid fatty acid 12.78%.Nature and flavor: bitter in the mouth; Cold in nature.Gui Jing: return kidney; Urinary bladder channel.Function cures mainly: inducing diuresis to remove edema; Heat-clearing and toxic substances removing.Main edema; Tympanites; Infantile malnutrition; Eczema; Skin infection; Venom.
Rhizoma Imperatae: base is former: this product is the dry rhizome of grass Herba Imperatae.Nature and flavor: sweet, cold.Gui Jing: return lung, stomach, urinary bladder channel.Effect: cooling blood for hemostasis, clearing away heat and promoting diuresis.Cure mainly: spit blood for heat in blood. epistaxis, hematuria, calentura excessive thirst, jaundice, edema, the puckery pain of pyretic stranguria; Acute nephritis edema.
Herba speranskiae tuberculatae: base is former: be the herb of euphorbia plant speranskia tuberculata.Chemical analysis: the germination twig of Impatientis is containing indole-3-acetonitrile.Stem contains Kaempferol-glycoside, Quercetin-3-glycoside, forms stricture of vagina India element-3-glycoside, cyanidin-3-glycoside.Leaf is containing 1,2,4-trihydroxynaphthalene-4-glycoside and the Arabic glucoside of the close phenol-3-of nimbecetin and mountain.Impatientis herb, containing P-hydroxybenzoic acid, gentisic acid, ferulic acid, P-coumaric acid, sinapic acid, caffeic acid, separately contains scopoletin.Leaf is containing cinnamate derivative, the Arabic glucoside of kaempferol-3-and kaempferol.Stem is containing kaempferol-3-glycoside, Quercetin, pelargonin, cyanidin, Herba delphinii grandiflori florigen.Nature and flavor: pungent; Warm in nature.Gui Jing: lung; Liver Channel.Function cures mainly: expelling wind and removing dampness; Relaxing muscles and tendons to promote blood circulation; Dissipating blood stasis for subsidence of swelling; Removing toxic substances ophthalmalgia.Main air pain of dampness syndrome; Muscles and bones contracture; The disturbance of lower legs due to pathogenic cold and dampness; Lumbar strain; Paralysis; Amenorrhea; Eczema scrotum; Furuncle toxic swelling.
Diplazium lanceum (Thunb): base is former: be the herb of the single leaf Diplazium donianum (Mett.) Tard. Blet. of Athyriaceae plant.Nature and flavor: bitter; Puckery; Be slightly cold; Nontoxic.Gui Jing: lung; Kidney channel.Function cures mainly: stop blooding treating stranguria; Heat-clearing and toxic substances removing.Main hemoptysis; Stranguria; Hematuria; Infantile malnutrition; Tinea pedis.
Herba Nasturth officinalis: base is former: be the herb of crucifer Nasturtium officinale.Chemical analysis: herb containing glucose Nasturtium officinale element and vitamin A, 13, C, protein, fat, saccharide (glucose, sucrose, fructose), organic acid.Also containing volatile ingredient: phenylpropyl alcohol eyeball, the pungent eyeball of 8-methyl mercapto, 9-methyl mercapto pelargonitrile, 3-butene nitrile, 7-methyl mercapto heptonitrile, benzene acetonitrile.Seed contains erucic acid, glucosinolates.Pharmacological action: 1. Nutrition: be imbued with vitamin A, C, D, thus nutritious.2. zest: seed also containing mustard oil, has intense stimulus.3. bacteriostasis: its aqueous extract can suppress the growth of escherichia coli, but to staphylococcus aureus then without effect.4. to stimulate the menstrual flow effect: herb can disturb embedding of ovum and gestation according to cloud, have the green water cress eating and boil to stimulate the menstrual flow, to miscarry abroad, contraception person.5. antagonist: the juice of squeezing can, to the tobaccoism of anti-rabbit, dog, be the antagonist of the latter.Nature and flavor: sweet; Cool; Light.Gui Jing: lung meridian.Function cures mainly: lung heat clearing; Removing heat from blood; Diuresis; Removing toxic substances.Main lung-heat type cough; Vitamin C deficiency; Inflammation of urinary system; Furunculosis pain is swollen; Skin pruritus.
It Luo Shui: base is former: be the juice in cucurbitaceous plant Fructus Luffae or Guangdong Fructus Luffae fragrant plant.Chemical analysis: Sucus Luffae contains Saponin, mucus, xylan, fat, protein, vitamin B and C etc.Nature and flavor: sweet in the mouth; Micro-hardship; Cold nature.Function cures mainly: heat-clearing and toxic substances removing; Relieving cough and resolving phlegm.Main lung abscess; Consumptive lung disease; Cough with asthma; Pulmonary tuberculosis; Summertime skin sore rash; Acne; Scald.
Pyrolusitum: base is former: be the Ore of oxide-based mineral pyrolusite.Chemical analysis: be mainly manganese dioxide (MnO
2), wherein manganese 63.1%, oxygen 36.8%.In addition, the still impurity such as iron content, cobalt, nickel.Nature and flavor: sweet; Flat; Salty; Cold; Nontoxic.Gui Jing: kidney; Liver Channel.Function cures mainly: blood stasis removing stops blooding; Reducing swelling and alleviating pain; Promoting tissue regeneration and ulcer healing.Main traumatic injury; Incised wound is hemorrhage; Carbuncle skin infection; Burn due to hot liquid or fire.
Folium et Ramulus Callicarpae nudiflorae: base is former: be the leaf with twig of Verbenaceae Callicarpa nudiflora.Chemical analysis: leaf is containing flavone, tannin, volatile oil and sugar etc.The effective ingredient that stops blooding in leaf is a kind of polysaccharide, can obtain arabinose, galactose etc. after acid hydrolysis.Pharmacological action: 1. anastalsis.2. on the impact of smooth muscle: Callicarpa nudiflora herb extracting solution has excitation to mice intestine in vitro, exempt from ear perfusion and can make vasoconstriction, it can by caused by mechanical pressure and vasoconstriction to gastral anastalsis.3. antibacterial action: Callicarpa nudiflora herb decoct in vitro has good bacteriostasis to staphylococcus aureus, Bacillus typhi, also has certain bacteriostasis to paracolon, bacterium flexneri, wherein better with flower, leaf effect.In addition leukocytic phagocytosis is promoted in addition.Nature and flavor: puckery micro-arduous; Flat.Gui Jing: heart channel.Function cures mainly: dissipating blood stasis stops blooding; Removing toxic substances and promoting subsidence of swelling.Main epistaxis; Hemoptysis; Spit blood; Have blood in stool; Traumatic injury congestive edema; Traumatic hemorrhage; Burn due to hot liquid or fire; Sore festers.
Fructus Citri: base is former: be rutaceae citron or fragrant round mature fruit.Pharmacological action: contained volatile oil has gentle stimulation to gastrointestinal tract, can promote to wriggle and digestive juice secretion in the intestines and stomach, get rid of enteral pneumatosis, and have phlegm-dispelling functions.1. antiinflammatory action: the hesperidin contained by this product to Cavia porcellus for want of vitamin C and cause eyes bulbar conjunctiva intravascular cells cohesion and capillary resistance reduce be improved effect, the cohesion of horse blood cell can be reduced.2. antivirus action: before hesperidin adds vesicle Stomatovirus, is put in mice fibrocyte in the hesperidin of 200 μ g/ml and hatches process in advance, can Cell protection not by virus infraction about 24 hours.Anticipate the infection of Hela cell energy flu-prevention virus.But its antiviral activity can eliminate by hyaluronidase.3. other effect: hesperidin has prevention cold injury and suppresses the aldehyde reductase effect of rat lens.Obacunone has the effect strengthening isolated rabbit intestinal tension force and amplitude.Nature and flavor: pungent; Bitter; Acid; Temperature.Gui Jing: liver; Lung; Spleen channel.Function cures mainly: regulating QI and lowering the adverseness; The chest stuffiness relieving reduces phlegm.Main breast abdominal distention is vexed; Distending pain over the hypochondrium; Cough with copious phlegm.
Caulis Panici miliacei: base is former: the stem stalk of grass broomcorn millet.Nature and flavor: pungent; Heat; Slightly poisonous.Function cures mainly: inducing diuresis to remove edema; Hemostasis; Removing toxic substances.Main dysuria; Edema; Hematuria during pregnancy; Foot gas; A bitter a kind of edible gourd is poisoning.
Herba Euphoubiae Hirtae: base is former: be herb or the whole herb with root of euphorbia plant Ramulus et Folium Bauhiniae Faberi.Chemical analysis: herb is containing freidelin, and β-Amyrin, hentriacontane, cupreol, again containing taraxerol, taraxerone, chondrillasterol, stigmasterol, Jambul alcohol, bark is plain, rhamnetin-3-rhamnoside.Stem contains freidelin, triacontanol, hentriacontanol, taraxerol, hentriacontane, β-Amyrin etc.Leaf is containing gallic acid, quercitrin, arbutin, 3,4-bis--O-gallic acid quininic acid, 2,4,6-tri--O-gallic acid-D-Glucose and 1,2,3,4,6-five-O-gallic acid-β-D-Glucose.Fresh flowers is containing benzoaric acid.Pharmacological action: Female guinea pigs gives Herba Euphoubiae Hirtae before period of sexual maturity, can make mammary gland accelerate to grow and lactogenic.It also has some diuresis, catharsis effect; Without antibacterial action, meaning 1:5-1:60 is also had to have some antibacterial action person.Nature and flavor: pungent; Acid; Frightened; Mild toxicity.Gui Jing: lung; Liver Channel.Function cures mainly: heat-clearing and toxic substances removing; Dampness removing is antipruritic; Lactogenesis.Main lung abscess; Acute mastitis; Dysentery; Have loose bowels; Pyretic stranguria; Hematuria; Eczema; Tinea pedis; Skin pruritus; Furuncle swelling toxin; Ulcerative gingivitis; Puerperal lactation deficiency.
Semen Trigonellae: base is former: be the seed of leguminous plant Semen Trigonellae.Chemical analysis: seed is containing alkaloids such as erythricine, carpaine, choline, trigonellines, and ruscogenin is diosgenin, Yamogenin and a small amount of gitogenin, trace Tigogenin mainly.Still isolate vitexin, vitexin-7-glycoside, orientin or the Arabic glucoside of isorientin, glucose rhamnose two glucoside of flavone, the flavonoid such as Quercetin, luteolin.Pharmacological action: trigonelline be it is generally acknowledged without pharmacological action; But also someone reports that it is in neuromuscular specimen, can reduce neural duration, be then first reduce to increase afterwards to the duration of muscle.Have lactogenic composition in the oil of seed, this composition is not containing iodine, nitrogen, sulfur, and without any gonadotropic Effect, the seed after deoiling contains the stodgy viscose glue of 50%, therefore has some catharsis effect.Seed also has and slight drives the effect of gutstring worm.Nature and flavor: bitter, temperature.Gui Jing: enter kidney, Liver Channel.Function cures mainly: kidney-replenishing, dispelling cold and dampness.Control colic of cold type, abdomen side of body distension, the disturbance of lower legs due to pathogenic cold and dampness, the soreness of waist of suffering from a deficiency of the kidney, sexual impotence.
Technical advantage of the present invention is also embodied in:
1,selected materials is all Chinese medicine material, and curative effect is remarkable, has no side effect, and has and prepares simple, economy feature easily.
2,raw material of Chinese medicine of the present invention is through dialectical compatibility, thus effective effect playing its removing damp-heat, removing toxic substances parasite killing, active ingredient is stablized, persistent, long shelf-life.
3,medicine source is easy to get, with low cost, can relieve patient ' s burden.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
embodiment 1treat a lavipeditum powder for beriberi, be prepared from by following bulk drugs, be weight portion (every part of 10g): the Radix Stemonae 9 parts; Flos seu Radix Impatientis nolitangeris 7 parts; Herba Actinstemmatis Lobati 10 parts; Rhizoma Imperatae 12 parts; Herba speranskiae tuberculatae 9 parts; Diplazium lanceum (Thunb) 11 parts; Herba Nasturth officinalis 8 parts; It Luo Shui 9 parts; Pyrolusitum 7 parts; Folium et Ramulus Callicarpae nudiflorae 10 parts; Fructus Citri 8 parts; Caulis Panici miliacei 9 parts; Herba Euphoubiae Hirtae 11 parts; Semen Trigonellae 9 parts.
A kind of preparation method for the treatment of the lavipeditum powder of beriberi is:
(1) Semen Trigonellae is eluriated clean with clear water, and be first placed in 42 ° of Chinese liquor and soak 10 hours, taking-up is dried, and then turns in steamer, slow fire heats steaming to well-done, is finally placed in parch container, and slow fire heats, and fries extremely to making sound, in yellow, taking-up cools, and is ground into fine powder, for subsequent use; Pyrolusitum is placed in charcoal fire, and intense fire is forged red, is placed in rice vinegar cancellation, repeats 3 times, cooling, and porphyrize powder is for subsequent use;
(2) Flos seu Radix Impatientis nolitangeris, Herba Actinstemmatis Lobati, Fructus Citri, Folium et Ramulus Callicarpae nudiflorae and Caulis Panici miliacei are placed in traditional Chinese medicine drying machine, in 55 DEG C of dryings 25 minutes, then adjust the temperature to 40 DEG C of dryings 1 hour, slightly cool, are placed in pulverizer and are ground into fine powder, for subsequent use;
(3) by the Radix Stemonae, Rhizoma Imperatae, Herba speranskiae tuberculatae, Diplazium lanceum (Thunb), Herba Nasturth officinalis and Herba Euphoubiae Hirtae are placed in medicine pot, add cold water to powder 3-5cm, intense fire heated and boiled, turn slow fire boiling three times, first time decocts 42 minutes, second time and third time decoct 22 minutes respectively, merge three decocting liquids, filter, Tian Luoshui is added in filtrate, mixing, be evaporated to paste, be cooled to room temperature, the ethanol (mass ratio of ethanol and thick paste is 1:2) that mass concentration is 70% is added in thick paste, leave standstill 22 hours, filter, distilling under reduced pressure is extremely without alcohol taste, vacuum drying gets dry extract, let cool, porphyrize, for subsequent use,
(4) the raw material medicated powder mixing after being processed step (1)-(3), crosses 55 mesh sieves, 78 DEG C of dry heat sterilizations 35 minutes, according to 20g/ bag metering, distributing, packaging and get final product.
The using method of gained lavipeditum powder of the present invention is: the warm water getting one bag of lavipeditum powder 1000-1500 milliliter about 40-45 DEG C is dissolved in basin, soaks and suffers from foot 30-40 minute, once a day, and seven days courses for the treatment of.
Model case: Wu XX, man, 55 years old, peasant.Patient's readme: suffer from beriberi and have a surplus for 5 years, during each outbreak, pruritus is hard to bear, and biped toe plays vesicle, skin festers because scratching, desquamation.Used the Drug therapy such as beriberi liquor, daktarin once, remission after medication, but recurred after drug withdrawal.Suffer from recent years to find always and thoroughly cure beriberi less than good recipe.Mentioned the worries of oneself afterwards when chatting with neighbours, by the agency of comes my institute on June 20th, 2011 and attempts treatment.Check: patient's biped toe festers, flowing water, pruritus, desquamation.Red tongue, yellow and greasy fur, wiry and frequent pulse, fungus microscope examination is positive.Be diagnosed as beriberi.
Use a kind of lavipeditum powder for the treatment of beriberi of the present embodiment gained, using method: the warm water getting one bag of lavipeditum powder 1000-1500 milliliter about 40-45 DEG C is dissolved in basin, soak and suffer from foot 30-40 minute, once a day, seven days courses for the treatment of.After treating two courses for the treatment of, patient is conscious, and pruritus alleviates, and skin symptom is clearly better, and continue two courses for the treatment of of use, pruritus thoroughly disappears, and rotten position skin recovers normal gradually, negative fungal examination.Patient fully recovers.Pay a return visit after half a year, without recurrence.
embodiment 2treat a lavipeditum powder for beriberi, be prepared from by following bulk drugs, be weight portion (every part of 10g): the Radix Stemonae 15 parts; Flos seu Radix Impatientis nolitangeris 14 parts; Herba Actinstemmatis Lobati 16 parts; Rhizoma Imperatae 18 parts; Herba speranskiae tuberculatae 17 parts; Diplazium lanceum (Thunb) 16 parts; Herba Nasturth officinalis 15 parts; It Luo Shui 16 parts; Pyrolusitum 13 parts; Folium et Ramulus Callicarpae nudiflorae 13 parts; Fructus Citri 12 parts; Caulis Panici miliacei 13 parts; Herba Euphoubiae Hirtae 15 parts; Semen Trigonellae 12 parts.
A kind of preparation method for the treatment of the lavipeditum powder of beriberi is:
(1) Semen Trigonellae is eluriated clean with clear water, and be first placed in 65 ° of Chinese liquor and soak 16 hours, taking-up is dried, and then turns in steamer, slow fire heats steaming to well-done, is finally placed in parch container, and slow fire heats, and fries extremely to making sound, in yellow, taking-up cools, and is ground into fine powder, for subsequent use; Pyrolusitum is placed in charcoal fire, and intense fire is forged red, is placed in rice vinegar cancellation, repeats 7 times, cooling, and porphyrize powder is for subsequent use;
(2) Flos seu Radix Impatientis nolitangeris, Herba Actinstemmatis Lobati, Fructus Citri, Folium et Ramulus Callicarpae nudiflorae and Caulis Panici miliacei are placed in traditional Chinese medicine drying machine, in 65 DEG C of dryings 45 minutes, then adjust the temperature to 50 DEG C of dryings 3 hours, slightly cool, are placed in pulverizer and are ground into fine powder, for subsequent use;
(3) by the Radix Stemonae, Rhizoma Imperatae, Herba speranskiae tuberculatae, Diplazium lanceum (Thunb), Herba Nasturth officinalis and Herba Euphoubiae Hirtae are placed in medicine pot, add cold water to powder 3-5cm, intense fire heated and boiled, turn slow fire boiling three times, first time decocts 54 minutes, second time and third time decoct 40 minutes respectively, merge three decocting liquids, filter, Tian Luoshui is added in filtrate, mixing, be evaporated to paste, be cooled to room temperature, the ethanol (mass ratio of ethanol and thick paste is 1:4) that mass concentration is 90% is added in thick paste, leave standstill 30 hours, filter, distilling under reduced pressure is extremely without alcohol taste, vacuum drying gets dry extract, let cool, porphyrize, for subsequent use,
(4) the raw material medicated powder mixing after being processed step (1)-(3), crosses 95 mesh sieves, 96 DEG C of dry heat sterilizations 55 minutes, according to 30g/ bag metering, distributing, packaging and get final product.
The using method of gained lavipeditum powder of the present invention is: the warm water getting one bag of lavipeditum powder 1000-1500 milliliter about 40-45 DEG C is dissolved in basin, soaks and suffers from foot 30-40 minute, once a day, and seven days courses for the treatment of.
embodiment 3treat a lavipeditum powder for beriberi, be prepared from by following bulk drugs, be weight portion (every part of 10g): the Radix Stemonae 10.5 parts; Flos seu Radix Impatientis nolitangeris 9 parts; Herba Actinstemmatis Lobati 12 parts; Rhizoma Imperatae 14 parts; Herba speranskiae tuberculatae 11 parts; Diplazium lanceum (Thunb) 12.5 parts; Herba Nasturth officinalis 10 parts; It Luo Shui 11 parts; Pyrolusitum 9 parts; Folium et Ramulus Callicarpae nudiflorae 11 parts; Fructus Citri 9 parts; Caulis Panici miliacei 10 parts; Herba Euphoubiae Hirtae 12 parts; Semen Trigonellae 10 parts.
A kind of preparation method for the treatment of the lavipeditum powder of beriberi is:
(1) Semen Trigonellae is eluriated clean with clear water, and be first placed in 45 ° of Chinese liquor and soak 12 hours, taking-up is dried, and then turns in steamer, slow fire heats steaming to well-done, is finally placed in parch container, and slow fire heats, and fries extremely to making sound, in yellow, taking-up cools, and is ground into fine powder, for subsequent use; Pyrolusitum is placed in charcoal fire, and intense fire is forged red, is placed in rice vinegar cancellation, repeats 4 times, cooling, and porphyrize powder is for subsequent use;
(2) Flos seu Radix Impatientis nolitangeris, Herba Actinstemmatis Lobati, Fructus Citri, Folium et Ramulus Callicarpae nudiflorae and Caulis Panici miliacei are placed in traditional Chinese medicine drying machine, in 58 DEG C of dryings 30 minutes, then adjust the temperature to 43 DEG C of dryings 1.5 hours, slightly cool, are placed in pulverizer and are ground into fine powder, for subsequent use;
(3) by the Radix Stemonae, Rhizoma Imperatae, Herba speranskiae tuberculatae, Diplazium lanceum (Thunb), Herba Nasturth officinalis and Herba Euphoubiae Hirtae are placed in medicine pot, add cold water to powder 3-5cm, intense fire heated and boiled, turn slow fire boiling three times, first time decocts 46 minutes, second time and third time decoct 26 minutes respectively, merge three decocting liquids, filter, Tian Luoshui is added in filtrate, mixing, be evaporated to paste, be cooled to room temperature, the ethanol (mass ratio of ethanol and thick paste is 1:2.5) that mass concentration is 75% is added in thick paste, leave standstill 24 hours, filter, distilling under reduced pressure is extremely without alcohol taste, vacuum drying gets dry extract, let cool, porphyrize, for subsequent use,
(4) the raw material medicated powder mixing after being processed step (1)-(3), crosses 65 mesh sieves, 82 DEG C of dry heat sterilizations 40 minutes, according to 23g/ bag metering, distributing, packaging and get final product.
The using method of gained lavipeditum powder of the present invention is: the warm water getting one bag of lavipeditum powder 1000-1500 milliliter about 40-45 DEG C is dissolved in basin, soaks and suffers from foot 30-40 minute, once a day, and seven days courses for the treatment of.
Model case: king XX, female, 63 years old, teacher.Patient's readme: double-legged toe, vola skin pruritus are existing has a surplus for 3 years, attempts the multiple method treatment of application always, but all fails thoroughly to cure.Especially after edible pungent stimulation food, aggravation, pruritus aggravation at night.During summer, the state of an illness is heavier, alleviates to symptom during winter.Household seeks good medicine for it always and wishes thoroughly to break away from disease, but has no resolution always.Introduce through friend afterwards, have the attitude of trying in arms and carry out my institute's inspection treatment on July 18th, 2012.Check: patient's biped, interphalangeal erosion, to chap, vola desquamation, microscopy fungus is positive.Be diagnosed as beriberi.
Use a kind of lavipeditum powder for the treatment of beriberi of the present embodiment gained, using method: the warm water getting one bag of lavipeditum powder 1000-1500 milliliter about 40-45 DEG C is dissolved in basin, soak and suffer from foot 30-40 minute, once a day, seven days courses for the treatment of.After treating two courses for the treatment of, patient is conscious, and pruritus alleviates, and rotten to the corn, symptom of chapping alleviates, and continue two courses for the treatment of of use, pruritus thoroughly disappears, and chaps, rotten to the corn place skin recovers normal, negative fungal examination gradually.Patient fully recovers.Pay a return visit after half a year, without recurrence.
embodiment 4treat a lavipeditum powder for beriberi, be prepared from by following bulk drugs, be weight portion (every part of 10g): the Radix Stemonae 13.5 parts; Flos seu Radix Impatientis nolitangeris 12 parts; Herba Actinstemmatis Lobati 14 parts; Rhizoma Imperatae 16 parts; Herba speranskiae tuberculatae 15 parts; Diplazium lanceum (Thunb) 14.5 parts; Herba Nasturth officinalis 13 parts; It Luo Shui 14 parts; Pyrolusitum 11 parts; Folium et Ramulus Callicarpae nudiflorae 12 parts; Fructus Citri 11 parts; Caulis Panici miliacei 12 parts; Herba Euphoubiae Hirtae 14 parts; Semen Trigonellae 11 parts.
A kind of preparation method for the treatment of the lavipeditum powder of beriberi is:
(1) Semen Trigonellae is eluriated clean with clear water, and be first placed in 60 ° of Chinese liquor and soak 14 hours, taking-up is dried, and then turns in steamer, slow fire heats steaming to well-done, is finally placed in parch container, and slow fire heats, and fries extremely to making sound, in yellow, taking-up cools, and is ground into fine powder, for subsequent use; Pyrolusitum is placed in charcoal fire, and intense fire is forged red, is placed in rice vinegar cancellation, repeats 6 times, cooling, and porphyrize powder is for subsequent use;
(2) Flos seu Radix Impatientis nolitangeris, Herba Actinstemmatis Lobati, Fructus Citri, Folium et Ramulus Callicarpae nudiflorae and Caulis Panici miliacei are placed in traditional Chinese medicine drying machine, in 62 DEG C of dryings 40 minutes, then adjust the temperature to 47 DEG C of dryings 2.5 hours, slightly cool, are placed in pulverizer and are ground into fine powder, for subsequent use;
(3) by the Radix Stemonae, Rhizoma Imperatae, Herba speranskiae tuberculatae, Diplazium lanceum (Thunb), Herba Nasturth officinalis and Herba Euphoubiae Hirtae are placed in medicine pot, add cold water to powder 3-5cm, intense fire heated and boiled, turn slow fire boiling three times, first time decocts 50 minutes, second time and third time decoct 36 minutes respectively, merge three decocting liquids, filter, Tian Luoshui is added in filtrate, mixing, be evaporated to paste, be cooled to room temperature, the ethanol (mass ratio of ethanol and thick paste is 1:3.5) that mass concentration is 85% is added in thick paste, leave standstill 28 hours, filter, distilling under reduced pressure is extremely without alcohol taste, vacuum drying gets dry extract, let cool, porphyrize, for subsequent use,
(4) the raw material medicated powder mixing after being processed step (1)-(3), crosses 85 mesh sieves, 92 DEG C of dry heat sterilizations 50 minutes, according to 27g/ bag metering, distributing, packaging and get final product.
The using method of gained lavipeditum powder of the present invention is: the warm water getting one bag of lavipeditum powder 1000-1500 milliliter about 40-45 DEG C is dissolved in basin, soaks and suffers from foot 30-40 minute, once a day, and seven days courses for the treatment of.
embodiment 5treat a lavipeditum powder for beriberi, be prepared from by following bulk drugs, be weight portion (every part of 10g): the Radix Stemonae 12 parts; Flos seu Radix Impatientis nolitangeris 10.5 parts; Herba Actinstemmatis Lobati 13 parts; Rhizoma Imperatae 15 parts; Herba speranskiae tuberculatae 13 parts; Diplazium lanceum (Thunb) 13.5 parts; Herba Nasturth officinalis 11.5 parts; It Luo Shui 12.5 parts; Pyrolusitum 10 parts; Folium et Ramulus Callicarpae nudiflorae 11.5 parts; Fructus Citri 10 parts; Caulis Panici miliacei 11 parts; Herba Euphoubiae Hirtae 13 parts; Semen Trigonellae 10.5 parts.
A kind of preparation method for the treatment of the lavipeditum powder of beriberi is:
(1) Semen Trigonellae is eluriated clean with clear water, and be first placed in 55 ° of Chinese liquor and soak 13 hours, taking-up is dried, and then turns in steamer, slow fire heats steaming to well-done, is finally placed in parch container, and slow fire heats, and fries extremely to making sound, in yellow, taking-up cools, and is ground into fine powder, for subsequent use; Pyrolusitum is placed in charcoal fire, and intense fire is forged red, is placed in rice vinegar cancellation, repeats 5 times, cooling, and porphyrize powder is for subsequent use;
(2) Flos seu Radix Impatientis nolitangeris, Herba Actinstemmatis Lobati, Fructus Citri, Folium et Ramulus Callicarpae nudiflorae and Caulis Panici miliacei are placed in traditional Chinese medicine drying machine, in 60 DEG C of dryings 35 minutes, then adjust the temperature to 45 DEG C of dryings 2 hours, slightly cool, are placed in pulverizer and are ground into fine powder, for subsequent use;
(3) by the Radix Stemonae, Rhizoma Imperatae, Herba speranskiae tuberculatae, Diplazium lanceum (Thunb), Herba Nasturth officinalis and Herba Euphoubiae Hirtae are placed in medicine pot, add cold water to powder 3-5cm, intense fire heated and boiled, turn slow fire boiling three times, first time decocts 48 minutes, second time and third time decoct 31 minutes respectively, merge three decocting liquids, filter, Tian Luoshui is added in filtrate, mixing, be evaporated to paste, be cooled to room temperature, the ethanol (mass ratio of ethanol and thick paste is 1:3) that mass concentration is 80% is added in thick paste, leave standstill 26 hours, filter, distilling under reduced pressure is extremely without alcohol taste, vacuum drying gets dry extract, let cool, porphyrize, for subsequent use,
(4) the raw material medicated powder mixing after being processed step (1)-(3), crosses 75 mesh sieves, 87 DEG C of dry heat sterilizations 45 minutes, according to 25g/ bag metering, distributing, packaging and get final product.
The using method of gained lavipeditum powder of the present invention is: the warm water getting one bag of lavipeditum powder 1000-1500 milliliter about 40-45 DEG C is dissolved in basin, soaks and suffers from foot 30-40 minute, once a day, and seven days courses for the treatment of.
test example:a kind of clinical practice for the treatment of the lavipeditum powder (embodiment 5) of beriberi of gained of the present invention:
1 data and method
1.1 physical data
Choose in October, 2010 in JIUYUE ,-2013 and carry out 346 routine beriberi patients of my institute treatment.Age 11-73 year, wherein male patient totally 179 example, female patient totally 167 example, the course of disease is the longest 9 years, the shortest 2 months.Wherein vesicle 127 example, erosive type 113 example, squama keratinization type 106 example.
1.2 clinical manifestation
(1) vesicle: between toe, sufficient edge, vola occur grain of rice size deeply in property vesicle, and evacuate or distribute in groups, bleb wall is thicker, and content is thorough clearly, not easily breaks.Dry desquamation after a few days, mutually merges and forms kerionic vesicle, tear bleb wall off, visible honeycomb substrate and the rotten to the corn face of cerise, violent pruritus.(2) erosive type: show as local horny layer of epidermis and macerate and turn white.Constantly rub during owing to walking about exfoliation, exposes the rotten to the corn face of cerise; Between severe patient toe seam, toe abdomen and vola intersection skin all can involve, acute pruritus, is mainly between 3,4,5 toes stitch.(3) squama keratinization type: symptom is vola, sufficient edge, heel portion skin keratin thicken, coarse, desquamation, and squama slabbing or little point-like, come off repeatedly.Winter toe seam between skin occur crack, summer produces vesicle, has pain.
1.3 Therapeutic Method
All patients are divided into experimental group and treatment group randomly, and two groups of patients are through statistical procedures in sex, age, the course of disease, and no statistical significance (P > 0.05), has comparability.Wherein experimental group uses a kind of lavipeditum powder for the treatment of beriberi of gained of the present invention, and using method is: the warm water getting one bag of lavipeditum powder 1000-1500 milliliter about 40-45 DEG C is dissolved in basin, soaks and suffers from foot 30-40 minute, once a day, and seven days courses for the treatment of.Matched group and experimental group, under identical time and environment, use the medicine (as Lan Meishu, Terbinafine hydrochloride emulsifiable paste, daktarin etc.) of other treatment scabies.Observe four courses for the treatment of of treatment altogether.
1.4 efficacy assessment standard
Cure: after treatment, clinical symptoms and sign disappear completely, and the direct microscopy of fungus or cultivation are negative, observe two months without recurrence;
Effective: after treatment, skin lesion symptom and pruritus degree obviously alleviate, the direct microscopy feminine gender of fungus or cultivation are negative;
Effective: after treatment, skin lesion and pruritis are alleviated to some extent, and the direct microscopy of fungus or cultivation are positive;
Invalid: after treatment, symptom and sign are without change or aggravation.
Total effective rate=(curing number of cases+effective number of cases+effectively number of cases)/total inspection case load × 100%.
1.5 therapeutic outcome
The therapeutic outcome of experimental group and matched group patient is as shown in table 1:
Table 1: the therapeutic outcome of two groups of patients compares
Therapeutic effect: experimental group cures 164 examples (71.3%), effective 37 examples (16.1%), effective 26 examples (11.3%), invalid 3 examples (1.3%), total effective rate is 98.7%, and matched group total effective rate is 77.6%, from result, the curative effect of medicine of the present invention is used obviously to be better than other conventional medication.
Scientific formulation of the present invention is reasonable, and wherein the Radix Stemonae has effect that is antibacterial, parasite killing; Flos seu Radix Impatientis nolitangeris expelling wind and removing dampness; Herba Actinstemmatis Lobati inducing diuresis to remove edema, heat-clearing and toxic substances removing; Herba Nasturth officinalis lung heat clearing, removing heat from blood, diuresis, removing toxic substances; The hemostasis of pyrolusitum blood stasis removing, reducing swelling and alleviating pain, promoting tissue regeneration and ulcer healing; The hemostasis of Folium et Ramulus Callicarpae nudiflorae dissipating blood stasis, removing toxic substances and promoting subsidence of swelling; Herba Euphoubiae Hirtae heat-clearing and toxic substances removing, dampness removing are antipruritic; Semen Trigonellae kidney-replenishing, dispelling cold and dampness.Full side's compatibility is precise and appropriate, and curative effect is obvious.All medicines also have the effect of clearing away heat and cooling blood, killing parasites for relieving itching while being used in reducing swelling and alleviating pain.In experimental group, total effective rate can reach 98.7%, and matched group is only 77.6%.
Finally it should be noted that, embodiment is the detailed description of the invention of optimum of the present invention, be not limited to the present invention, although with reference to previous embodiment to invention has been detailed description, for a person skilled in the art, it still can be modified to the technical scheme described in foregoing embodiments, or carries out equivalent replacement to wherein portion of techniques feature.Within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (10)
1. treat a lavipeditum powder for beriberi, it is characterized in that, be prepared from by following bulk drugs, be weight portion: Radix Stemonae 9-15; Flos seu Radix Impatientis nolitangeris 7-14; Herba Actinstemmatis Lobati 10-16; Rhizoma Imperatae 12-18; Herba speranskiae tuberculatae 9-17; Diplazium lanceum (Thunb) 11-16; Herba Nasturth officinalis 8-15; It Luo Shui 9-16; Pyrolusitum 7-13; Folium et Ramulus Callicarpae nudiflorae 10-13; Fructus Citri 8-12; Caulis Panici miliacei 9-13; Herba Euphoubiae Hirtae 11-15; Semen Trigonellae 9-12.
2. a kind of lavipeditum powder for the treatment of beriberi as claimed in claim 1, is characterized in that, be prepared from by following bulk drugs, be weight portion: Radix Stemonae 10.5-13.5; Flos seu Radix Impatientis nolitangeris 9-12; Herba Actinstemmatis Lobati 12-14; Rhizoma Imperatae 14-16; Herba speranskiae tuberculatae 11-15; Diplazium lanceum (Thunb) 12.5-14.5; Herba Nasturth officinalis 10-13; It Luo Shui 11-14; Pyrolusitum 9-11; Folium et Ramulus Callicarpae nudiflorae 11-12; Fructus Citri 9-11; Caulis Panici miliacei 10-12; Herba Euphoubiae Hirtae 12-14; Semen Trigonellae 10-11.
3. a kind of lavipeditum powder for the treatment of beriberi as claimed in claim 1, is characterized in that, be prepared from by following bulk drugs, be weight portion: the Radix Stemonae 12; Flos seu Radix Impatientis nolitangeris 10.5; Herba Actinstemmatis Lobati 13; Rhizoma Imperatae 15; Herba speranskiae tuberculatae 13; Diplazium lanceum (Thunb) 13.5; Herba Nasturth officinalis 11.5; It Luo Shui 12.5; Pyrolusitum 10; Folium et Ramulus Callicarpae nudiflorae 11.5; Fructus Citri 10; Caulis Panici miliacei 11; Herba Euphoubiae Hirtae 13; Semen Trigonellae 10.5.
4. a kind of preparation method for the treatment of the lavipeditum powder of beriberi as described in claim 1-3, it is characterized in that, step is as follows:
(1) Semen Trigonellae is eluriated clean with clear water, first be placed in Chinese liquor to soak 10-16 hour (be preferably placed in Chinese liquor and soak 12-14 hour), taking-up is dried, and then turns in steamer, slow fire heating is steamed to well-done, finally be placed in parch container, slow fire heats, and fries extremely to making sound, in yellow, taking-up cools, and is ground into fine powder, for subsequent use; Pyrolusitum is placed in charcoal fire, and intense fire is forged red, is placed in rice vinegar cancellation, and repeat 3-7 time (preferably repeating 4-6 time), cooling, porphyrize powder is for subsequent use;
(2) Flos seu Radix Impatientis nolitangeris, Herba Actinstemmatis Lobati, Fructus Citri, Folium et Ramulus Callicarpae nudiflorae and Caulis Panici miliacei are placed in traditional Chinese medicine drying machine, in 55-65 DEG C of dry 25-45 minute (being preferable over 58-62 DEG C of dry 30-40 minute), then adjust the temperature to 40-50 DEG C of dry 1-3 hour (preferably adjusting the temperature to 43-47 DEG C of dry 1.5-2.5 hour), slightly cool, be placed in pulverizer and be ground into fine powder, for subsequent use;
(3) by the Radix Stemonae, Rhizoma Imperatae, Herba speranskiae tuberculatae, Diplazium lanceum (Thunb), Herba Nasturth officinalis and Herba Euphoubiae Hirtae are placed in medicine pot, add cold water to powder 3-5cm, intense fire heated and boiled, turn slow fire boiling three times, first time decocts 42-54 minute (preferably first time decocts 46-50 minute), second time and third time decoct 22-40 minute (preferably second time and third time decoct 26-36 minute respectively) respectively, merge three decocting liquids, filter, Tian Luoshui is added in filtrate, mixing, be evaporated to paste, be cooled to room temperature, ethanol is added in thick paste, leave standstill, filter, distilling under reduced pressure is extremely without alcohol taste, vacuum drying gets dry extract, let cool, porphyrize, for subsequent use,
(4) by step (1)-(3) process after raw material medicated powder mixing, sieve, dry heat sterilization 35-55 minute (preferred dry heat sterilization 40-50 minute), according to 20-30g/ bag metering (preferably according to the metering of 23-27g/ bag) subpackage and get final product.
5. a kind of preparation method for the treatment of the lavipeditum powder of beriberi according to claim 4, is characterized in that, in step (1), the number of degrees of Chinese liquor are 42 °-65 ° (number of degrees of preferred Chinese liquor are 45 °-60 °, and the number of degrees of the Chinese liquor be more preferably are 55 °).
6. a kind of preparation method for the treatment of the lavipeditum powder of beriberi according to claim 4, it is characterized in that, in step (3), the mass concentration of ethanol is the mass concentration of the preferred ethanol of 70%-90%(is 75%-85%, and the mass concentration of the ethanol be more preferably is 80%).
7. a kind of preparation method for the treatment of the lavipeditum powder of beriberi according to claim 4, it is characterized in that, in step (3), the mass ratio of ethanol and thick paste is the mass ratio of the preferred ethanol of 1:2-4(and thick paste is 1:2.5-3.5, and the ethanol be more preferably and the mass ratio of thick paste are 1:3).
8. a kind of preparation method for the treatment of the lavipeditum powder of beriberi according to claim 4, is characterized in that, leaves standstill 22-30 hour (preferred standing 24-28 hour, what be more preferably leaves standstill 26 hours) in step (3).
9. a kind of preparation method for the treatment of the lavipeditum powder of beriberi according to claim 4, is characterized in that, the middle 55-95 mesh sieve excessively of step (4) (preferred 65-85 mesh sieve excessively, mistake 75 mesh sieve be more preferably).
10. a kind of preparation method for the treatment of the lavipeditum powder of beriberi according to claim 4, it is characterized in that, in step (4), the temperature of dry heat sterilization is 78-96 DEG C (temperature of preferred dry heat sterilization is 82-92 DEG C, and the temperature of the dry heat sterilization be more preferably is 87 DEG C).
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| 孙莹等: "手足癣临床病案分析105例", 《中国当代医药》 * |
| 李雪松等: "中药熏洗治疗手足癣感染疗效观察", 《吉林中医药》 * |
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