CN104970258A - Compound feed additive with antioxidant function capable of relieving mycotoxicosis of piggy - Google Patents
Compound feed additive with antioxidant function capable of relieving mycotoxicosis of piggy Download PDFInfo
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- CN104970258A CN104970258A CN201510439716.6A CN201510439716A CN104970258A CN 104970258 A CN104970258 A CN 104970258A CN 201510439716 A CN201510439716 A CN 201510439716A CN 104970258 A CN104970258 A CN 104970258A
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Abstract
The invention discloses a compound feed additive with an antioxidant function capable of relieving mycotoxicosis of a piggy. The compound feed additive comprises the following components in percentage by weight: 1-2% of vitamin A, 3.23-4% of vitamin C, 5.11-6% of vitamin E, 3-4% of selenium yeast, 2-3% of grape seed proanthocyanidins and 81-85% of mixture of rice chaff and husks. The compound feed additive disclosed by the invention aims at a toxic mechanism of mycotoxin, selects a natural antioxidant as the raw material, adopts a reasonable compounding ratio of the components and has better relieving effects on oxidative injuries, structural damage and growth inhibition, which are caused by the mycotoxin, of intestinal tracts of an animal; besides, the compound feed additive with the antioxidant function, disclosed by the invention, has a better relieving effect on various animal toxic symptoms caused by the mycotoxin in the practice production; the components of the additive disclosed by the invention have the characteristics of safety and nutrition, micro nutritional substances in the feed cannot be adsorbed, and the breeding efficiency can be improved.
Description
Technical field
The present invention relates to a kind of feed addictive, particularly a kind of anti-oxidation function composite feed additive alleviating piglet mycotoxicosis.
Background technology
At present, feedstuff and mixed feed because of mycotoxin contamination be the emphasis that aquaculture is paid close attention to the harm that livestock and poultry are caused always.According to U.S. FAO (Food and AgricultureOrganization), about there are the crops of 25% in the whole world by mycotoxin contamination, about has the crops of 2% seriously to lose feeding value because of contaminated.Search for food by after the diet of mycotoxin contamination, breeding performonce fo animals decline, internal organs generation pathology, immunity reduce.At present, by adding mold toxin sorbent in feed, to reduce the absorption of animal to mycotoxin be apply maximum poison-removing methods in actual production.But adsorbent product Chinese pennisetum green bristlegrass is uneven on the market, and the broad spectrum activity of adsorbent own is poor, only has good adsorption effect to a kind of or two kinds of mycotoxins, and the micro-nutrient composition in possibility adsorption feed.In actual production, feedstuff and mixed feed often suffer the pollution of multiple mycotoxin, and adding adsorbent can not effectively adsorb whole mycotoxin.In addition, physics detoxification, chemical detoxication are because of trivial operations, on the destruction of feed nutrition material and affect the technological deficiencies such as feed palatability and cannot widely use in production practices.Using the biological detoxication method of enzymolysis and fermentable as novel detoxicating mycotoxin mode, although achieve some effects in detoxicating mycotoxin, but because the method is high to environmental requirement, cost is wayward, and the security of converted product needs to be investigated, be also difficult to promote the use of in actual production.Further, for mycotoxin entered cause poisoning in animal body when, above detoxicating mycotoxin method cannot alleviate poisoning symptom.Therefore, from toxicity of mycotoxins mechanism, develop efficient compound additive and seem particularly important.
Under normal physiological status, in animal body, the generation of active oxygen radical and removing are in dynamic equilibrium, and when oxygen radical in body produces too much or antioxidant ability of organism declines, this balance will be broken, and causes oxidative stress.Research shows, causes body oxidative stress may be one of mechanism of action of toxicity of mycotoxins.Therefore, in feed, add antioxidant may be the effective measures that mycotoxin animal is taken in protection.
Summary of the invention
Object of the present invention is exactly for the deficiencies in the prior art, from toxicity of mycotoxins mechanism, provides a kind of anti-oxidation function composite feed additive alleviating piglet mycotoxicosis, alleviates mycotoxin to piglet growth performance and enteron aisle structural damage.
The technical solution adopted for the present invention to solve the technical problems is:
Alleviate an anti-oxidation function composite feed additive for piglet mycotoxicosis, its component and mass percentage content are:
Described system chaff is as the carrier playing filling effect.
Above-described each nutrient has important effect for raising piglet oxidation resistance and maintenance enteron aisle structural integrity.
Vitamin A: the synthesis of involved in sugar albumen, maintains normal formation and the growth of epithelium, promotes cell proliferation and growth, be conducive to the reparation of mycotoxin stressed condition lower body; The synthesis of Promote immunity globulin, improves immunity of organisms, effectively alleviates the immunosupress that mycotoxin causes.
Vitamin E: as a kind of important liposoluble vitamin, by being immune against attacks with combined with radical Cell protection device film in location and cell, has synergy with vitamin C.
Vitamin C: as a kind of traditional natural, have very strong reduction, vitamin E radical reduction is become reduced form vitamin E, remove body free radical, the oxidative stress preventing mycotoxin from causing is to the damage of animal.
Yeast selenium: participate in glutathione peroxidase (G1utathione peroxidase as inorganic microelement important in body, GSH-px), the synthesis of sulfurtransferase and sulphur hydrogen reduction albumen, effectively can alleviate body oxidative stress and Apoptosis that mycotoxin causes.
Grape pip procyanidin: as a kind of natural materials with active phenolic hydroxyl structure, by phenolic hydroxyl group directly in conjunction with free radical, alleviates oxidative stress; Chelating diformazan iron ion reduces the hydroxy radical of Feton reaction generation to the damage of cell; Activities of antioxidant enzymes can also be improved to improve antioxidant ability of organism.
A kind of anti-oxidation function composite feed additive alleviating piglet mycotoxicosis of the present invention, its addition in feed is 3 kg/ton.
The invention has the beneficial effects as follows, the present invention is from toxicity of mycotoxins mechanism, select natural to be raw material, adopt rational component proportion, the animal intestinal oxidative damage caused for mycotoxin, structural deterioration and growth inhibition have good mitigation.Meanwhile, the animal poisoning symptom that anti-oxidation function composite feed additive of the present invention causes for multiple mycotoxin in practice production has good remission effect.Additive component of the present invention has the feature of safety, nutrition, can not trace nutrient in adsorption feed, can improve cultivation efficiency.
Detailed description of the invention
Below in conjunction with embodiment, invention is described further.
Alleviate an anti-oxidation function composite feed additive for piglet mycotoxicosis, its component and mass percentage content are:
Described system chaff is as the carrier playing filling effect.
A kind of anti-oxidation function composite feed additive alleviating piglet mycotoxicosis of the present invention, its addition in feed is 3 kg/ton.
Embodiment 1
Alleviate an anti-oxidation function composite feed additive for piglet mycotoxicosis, its component and mass percentage content are: vitamin A: 1.67%, vitamin C: 3.23%, vitamin E: 5.11%, yeast selenium: 3.33%, grape pip procyanidin: chaff of 2.63%, uniting: 84.03%.
In order to verify effect of the present invention, this invention shows below at the effect on pig farm, Sichuan:
By adding 0.3% additive of the present invention in containing mycotoxin (main containing AFB1 and fumonisins) piglet (body weight is at about 7.5kg) daily ration, the production performance of piglet and intestinal health situation all comparatively mycotoxin group are good.
This invention product of table 1 improves effect table to piglet growth performance
| Process | Mycotoxin group | Additive group |
| Test piglet head number | 30 | 30 |
| Average daily gain (g/d) | 407.45 | 412.07 |
| Average daily ingestion amount (g/d) | 690.38 | 673.58 |
| Feedstuff-meat ratio | 1.69 | 1.63 |
This invention product of table 2 improves effect table to piglet serum diamine oxidase (Diamine oxidase, DAO) activity
| Process | Mycotoxin group | Additive group |
| Test piglet head number | 30 | 30 |
| 15th day DAO activity (IU/L) | 128.89 | 120.28 |
| 30th day DAO activity (IU/L) | 126.62 a | 108.26 b |
This invention product of table 3 improves effect table to Jejunum of Piglets redox state
| Process | Mycotoxin group | Additive group |
| Test piglet head number | 30 | 30 |
| MDA (nmol/mg prot) | 0.69 a | 0.56 b |
| TAC (U/mg prot) | 0.22 b | 0.31 a |
| Superoxide dismutase (U/mg prot) | 121.78 b | 150.66 a |
| Glutathione peroxidase (U/mg prot) | 15.32 | 20.03 |
This invention product of table 4 improves effect table to Jejunum of Piglets Epithelial Cell Apoptosis
| Process | Mycotoxin group | Additive group |
| Test piglet head number | 30 | 30 |
| Apoptosis rate (%) | 9.17 a | 5.50 b |
Embodiment 2
Alleviate an anti-oxidation function composite feed additive for piglet mycotoxicosis, its component and mass percentage content are: vitamin A: 1%, vitamin C: 3.5%, vitamin E: 5.67%, yeast selenium: 3%, grape pip procyanidin: chaff of 2%, uniting: 84.83%.
In order to verify effect of the present invention, this invention shows below at the effect on pig farm, Sichuan:
By adding 0.3% additive of the present invention in containing mycotoxin (mainly containing AFB1, zearalenone, vomitoxin and T-2 toxin) piglet (body weight is at about 8kg) daily ration, the production performance of piglet and intestinal health situation all comparatively mycotoxin group are good.
This invention product of table 5 improves effect table to piglet growth performance
| Process | Mycotoxin group | Additive group |
| Test piglet head number | 36 | 36 |
| Average daily gain (g/d) | 411.87 | 432.80 |
| Average daily ingestion amount (g/d) | 683.79 | 679.42 |
| Feedstuff-meat ratio | 1.68 | 1.59 |
This invention product of table 6 improves effect table to Jejunum of Piglets redox state
| Process | Mycotoxin group | Additive group |
| Test piglet head number | 36 | 36 |
| MDA (nmol/mg prot) | 0.71 a | 0.55 b |
| TAC (U/mg prot) | 0.24 b | 0.37 a |
| Superoxide dismutase (U/mg prot) | 119.72 b | 148.29 a |
| Glutathione peroxidase (U/mg prot) | 19.36 b | 22.75 a |
Embodiment 3
Alleviate an anti-oxidation function composite feed additive for piglet mycotoxicosis, its component and mass percentage content are; Vitamin A: 2%, vitamin C: 4%, vitamin E: 6%, yeast selenium: 4%, grape pip procyanidin: chaff of 3%, uniting: 81%.
In order to verify effect of the present invention, this invention shows below at the effect on pig farm, Sichuan:
By adding 0.3% additive of the present invention in containing mycotoxin (main containing AFB1 and zearalenone) piglet (body weight is at about 8.5kg) daily ration, the production performance of piglet and intestinal health situation all comparatively mycotoxin group are good.
This invention product of table 7 improves effect table to piglet growth performance
| Process | Mycotoxin group | Additive group |
| Test piglet head number | 40 | 40 |
| Average daily gain (g/d) | 439.88 | 445.02 |
| Average daily ingestion amount (g/d) | 717.02 | 704.98 |
| Feedstuff-meat ratio | 1.64 | 1.59 |
This invention product of table 8 improves effect table to Jejunum of Piglets redox state
| Process | Mycotoxin group | Additive group |
| Test piglet head number | 40 | 40 |
| MDA (nmol/mg prot) | 0.71 a | 0.58 b |
| TAC (U/mg prot) | 0.29 b | 0.48 a |
| Superoxide dismutase (U/mg prot) | 117.39 b | 149.60 a |
| Glutathione peroxidase (U/mg prot) | 20.78 b | 24.14 a |
Application result shows: of the present inventionly a kind ofly alleviate anti-oxidation function composite feed additive mould in piglet mycotoxin, reduces the harm of mycotoxins in feed to piglet growth performance and intestinal health, improves cultivation efficiency.
Above-mentioned discussion and case study on implementation are only for illustrating specific embodiments of the present invention, and limit absolutely not its actual range, protection scope of the present invention is as the criterion with claims.
Claims (2)
1. alleviate an anti-oxidation function composite feed additive for piglet mycotoxicosis, it is characterized in that, its component and mass percentage content are:
Described system chaff is as the carrier playing filling effect.
2. a kind of anti-oxidation function composite feed additive alleviating piglet mycotoxicosis according to claim 1, its addition in feed is 3 kg/ton.
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Cited By (2)
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| CN107136334A (en) * | 2017-06-29 | 2017-09-08 | 中国科学院亚热带农业生态研究所 | A kind of feature compound feed additive for alleviating the poisoning of weanling pig vomitoxin |
| CN110724662A (en) * | 2019-08-08 | 2020-01-24 | 湖南农业大学 | Method for applying L-selenomethionine in animal cell antioxidation and product thereof |
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