CN1049600C - Chinese herbal medicine oral liquor for curing wind-heat common cold and its preparing method - Google Patents

Abstract

The present invention relates to a yaohuang oral liquid and a preparation method thereof, wherein the yaohuang oral liquid is a t traditional Chinese medicinal. The yaohuang oral liquid is characterized in that traditional Chinese medicinal materials of bupleurum root and scutellaria root are adopted as raw materials, the effective components of bupleurum root volatile oil, saikosaponin, baicalin, etc. are extracted from the raw materials, and the effective components are purified, compounded with liquid, sterilized and packaged by filling to obtain the yaohuang oral liquid. When the yaohuang oral liquid is used for treating wind-heat type common colds, the total clinical effective rate is 93.40%, and the rate of returning body temperature to normal within 48 hours reaches 60.40%; the total clinical effective rate for the main symptoms of the wind-heat type common colds, such as fevers, headaches, pharyngalgia, stuffy noses, rhinorrhea, whole body malaise, etc. is more than 86%; the yaohuang oral liquid has no adverse reaction in the process of clinical observation and is a novel medicine for treating wind-heat type common colds, which has obvious effect and high curative effect.

Description

A kind of Chinese medicine oral liquid and preparation method for the treatment of anemopyretic cold

The invention belongs to a kind of Chinese medicine preparation, especially treat the yellow oral liquid of bavin of anemopyretic cold.

Influenza is commonly encountered diseases, frequently-occurring disease clinically, also is the principal disease that threatens human health.Nosetiology confirms that the flu more than 90% is a viral infection, and western medicine effects such as use antibiotics are all undesirable, and therefore, using the treatment by Chinese herbs influenza is present research direction.The tradition traditional Chinese medical science thinks that flu is a kind of clinical common disease, and wherein anemopyretic cold is particularly common.When having some inkling of a cold, adopt " cold-pungent and diaphoretic prescriptions " more, but flu increase the weight of to outside pathogenic factor in the exterior is arranged, in when interior-heat is arranged, often need give " expelling pathogenic factors from muscles for reducing heat " class Chinese medicine.But this type of Chinese patent medicine extremely lacks at present.

The purpose of this invention is to provide a kind of quick-acting, Chinese medicine oral liquid efficiently for the treatment of anemopyretic cold.The present invention utilizes the hot pathogenic wind-heat that looses of Radix Bupleuri, reconciling superficies and interior, resolving depression soothing liver-QI; Be aided with Radix Scutellariae heat clearing and damp drying, eliminating fire and detoxication, clearing heat secreting bile, two medicine mutual reinforcements between are usefulness, receive the merit of clearing away heat and expelling pathogen in the exterior altogether.Pharmacodynamics shows that the present invention can obviously reduce the hyperpyrexia that rabbit is caused by typhoid fever, paratyphoid vaccine, and can obviously suppress the growth and breeding of influenza A virus and Influenza B virus; Significantly alleviate mice ear, and can suppress the growth of rat agar granuloma, tangible antiinflammatory action is arranged, alpha streptococcus, group B streptococcus, micrococcus catarrhalis, streptococcus pneumoniae etc. are all had the obvious suppression effect.

Yellow oral liquid of bavin of the present invention and preparation method thereof: it is characterized in that producing the yellow oral liquid of 1000 milliliters of bavins, required pharmaceutical formulation contains Radix Bupleuri 500-600 gram, Radix Scutellariae 450-550 gram, sodium benzoate 2.5-3 gram.Process for preparing medicine: Radix Scutellariae is decocted with water twice, and each 1 hour, collecting decoction filtered, and filtrate adds sulphuric acid and transfers PH to 2, leaves standstill, and the leaching precipitation, with an amount of washing with alcohol after drying, standby; With Radix Bupleuri steam distillation volatile matter distillation oil, the aqueous solution after distillation device is in addition placed; Medicinal residues extracting in water secondary, 2 hours for the first time, 1 hour for the second time, to filter, filtrate concentrates, and concentrated solution adds ethanol, makes pure content reach 60%, cold preservation (2-2 ℃) 24 hours; Filter, reclaim ethanol, concentrated solution, add Radix Scutellariae extract, adjust PH but, add water to volume, cold preservation 48 hours is filtered, and adds the Radix Bupleuri volatile oil distillate, sucrose, sodium benzoate, fill, sterilization.

Using method of the present invention: every day three times, each 1-2 props up.

Characteristics of the present invention and effect are; The yellow oral liquid of bavin of the present invention has clearing away heat and expelling pathogen in the exterior, the effect of the hot wind heat of loosing.Clinically cure mainly the heating that causes by anemopyretic cold, the whole body is uncomfortable, diseases such as headache and dizziness, laryngopharynx swelling and pain.Show that through three tame hospital clinical observed results the yellow oral liquid treatment anemopyretic cold of bavin of the present invention total effective rate reaches 93.4%, wherein total obvious effective rate is 60.38%; The temperature recovery natural rate of interest reaches 60.4% in 48 hours; For the heating of anemopyretic cold primary symptom, headache, pharyngalgia, nasal obstruction watery nasal discharge, the uncomfortable clinical aggregate efficiency in the whole body all more than 86%.Have rapid-actionly, it is fast to bring down a fever, and not repeatedly, improves the rapid characteristics of symptom after bringing down a fever.In the clinical observation process, do not see untoward reaction, safe in utilization, be that a kind of curative effect is reliable, the new drug of quick-acting treatment flu efficiently.

Embodiment:

Get Radix Bupleuri 550g, Radix Scutellariae 500g places Radix Scutellariae in the extraction pot, decocts with water secondary, and each 1 hour, collecting decoction filtered, and filtrate adds sulphuric acid and transfers PH to 2, leaves standstill, and the leaching precipitation is washed after drying in right amount with ethanol, and is standby; Radix Bupleuri is put in the extraction pot, and with steam distillation volatile matter distillation oil, the aqueous solution after distillation device is in addition placed; Medicinal residues extracting in water secondary, 2 hours for the first time, 1 hour for the second time, filter, filtrate concentrates, and concentrated solution adds ethanol, make to contain alcohol amount and reach 60%, cold preservation (2-2 ℃) 24 hours is filtered, reclaim ethanol, get concentrated solution, add Radix Scutellariae extract, adjust pH value, add water to volume, cold preservation 48 hours (2-2 ℃); Filter, add the Radix Bupleuri volatile oil distillate, sucrose 150g, sodium benzoate 3g adds water to 1000ml, stir evenly, fill, sterilization, the yellow oral liquid of bavin of the present invention.

Claims (1)

1. the yellow oral liquid of bavin for the treatment of anemopyretic cold is characterized in that producing the yellow oral liquid of 1000 milliliters of bavins, and required pharmaceutical formulation contains Radix Bupleuri 500-600 gram, Radix Scutellariae 450-550 gram, sucrose 100-150 gram, sodium benzoate 2-3 gram, above process for preparing medicine: with the Radix Scutellariae person's secondary that adds the decocting, each 1 hour, filter, filtrate adds sulphuric acid and transfers PH to 2, leaves standstill, the leaching precipitation is with an amount of washing with alcohol after drying; Behind the Radix Bupleuri volatile matter distillation oil, decoct with water secondary, 2 hours for the first time, 1 hour for the second time, to filter, filtrate concentrates, and concentrated solution adds ethanol to be made and contains the alcohol amount and reach 60%, cold preservation 24 hours (2-2 ℃); Filter, reclaim ethanol, add Radix Scutellariae extract, adjust pH value, add water-cooled and hide 48 hours (2-2 ℃) to the greatest extent; Filter, add the Radix Bupleuri volatile oil distillate, add sucrose, sodium benzoate, fill, sterilization.