CN104958188A - Composite ferment toothpaste and preparation method thereof - Google Patents
Composite ferment toothpaste and preparation method thereof Download PDFInfo
- Publication number
- CN104958188A CN104958188A CN201510313488.8A CN201510313488A CN104958188A CN 104958188 A CN104958188 A CN 104958188A CN 201510313488 A CN201510313488 A CN 201510313488A CN 104958188 A CN104958188 A CN 104958188A
- Authority
- CN
- China
- Prior art keywords
- toothpaste
- composite enzyme
- ferment
- enzyme toothpaste
- additive
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Cosmetics (AREA)
Abstract
The invention provides a composite ferment toothpaste and a preparation method thereof, and belongs to the technical field of daily use cleaning products. The composite ferment toothpaste mainly comprises, by mass, 40-50% of a humectant, 2-3% of a surfactant, 2-4% of a thickener, 35-50% of an additive, 1-5% of protein decomposition ferment, 0.1-2% of starch decomposition ferment, 0.1-2% of fat decomposition ferment, and the balance of water. The method is characterized in that all above raw materials are mixed in proportion, and are uniformly stirred to obtain the composite ferment toothpaste. The composite ferment toothpaste does not contain a rubbing agent or fluoride, and contains the protein decomposition ferment, the fat decomposition ferment and the starch decomposition ferment to realize tooth and oral cavity cleaning purposes. The preparation method of the composite ferment toothpaste has the advantages of simple process, suitableness for large scale production, easy obtaining of commercial raw materials, simple formula and low cost.
Description
Technical field
The present invention relates to daily cleaning articles for use technical field, in particular to a kind of composite enzyme toothpaste and preparation method thereof.
Background technology
Toothpaste is cleaning supplies conventional in daily life, has very long history.Along with the development of science and technology, technological equipment update and perfect, various types of toothpaste is come out one after another, quality and the class of product improve constantly, present toothpaste variety by single clean type toothpaste, develops into great variety of goods, diverse in function, the Mobyneb toothpaste of up to a hundred brands, meets the needs of different levels level of consumption.
Toothpaste is not the magic weapon of healthy tooth to select toothpaste first will know, the assistant product that it is just brushed teeth, and has friction effect and removes bacterial plaque, and clean polishing facing, makes the effect of oral cavity refreshing.The toothpaste that China uses is divided into ordinary toothpaste, fluoride dental cream and medicated toothpaste three major types.
The Main Ingredients and Appearance of ordinary toothpaste comprises abrasive, purificant, wetting agent, antiseptic, aromatic, has the effect that general toothpaste is total, if dental health situation is better, selects ordinary toothpaste.
But along with development in science and technology, it is found that fluoride can the effect of preventing decayed tooth, and facts have proved for many years, after fluoride and teeth contact, make easily to be formed not easily molten fluor-apatite by the apatite hydroxide of acid dissolve in dental tissue, thus improve the resistance to corrosion of tooth.There are some researches prove, conventional this toothpaste, morbidity of dental caries reduces about 40%.Fluoride has sodium fluoride, potassium fluoride, stannous fluoride and sodium monofluorophosphate.But know that fluorine is a kind of chronic noxious substance, fluorine does not participate in metabolism in vivo, can accumulate in vivo always, when fluorine intake is too much, can osteofluorosis be caused.National regulation, adding fluorine toothpaste free fluorine between 500-1500ppm, should pay special attention to, 3-4 year before unsuitable for children use because the toothpaste of 1/8-1/4 may be swallowed in stomach by them.
Medicated toothpaste is then add certain medicine on the basis of ordinary toothpaste, and when brushing teeth, toothpaste arrives in dental surface or around teeth environment, by the effect of medicine, reduces dental plaque, thus plays the effect of anti-dental caries and periodontal disease.Medicated toothpaste pole by the favor of people, and utilizes toothpaste to promote the medicine with prevention effects or therapeutic efficiency to be a kind of comparatively ideal mode.But medicated toothpaste also has its unfavorable aspect, first, toothpaste can not keep the long time in mouth, namely gargled, make medicine be difficult to play drug effect at short notice, and special medicament dosage also must be avoided stimulating soft tissue in mouth, thus enough valid density can not be brought up to, the effect of toothpaste itself, often hinder by dirt in mouth or limit by morphological characteristic, be thus difficult to reach the region of real morbidity.
They are two years old, medicine in toothpaste, often because standing time for a long time other chemical change occurs, lose original drug effect, active drug again Chang Yin is unsuitable for abnormal flavour and puts into toothpaste, also has the problem of drug resistance in addition, and these factors all show that the unsuitable life-time service of medicated toothpaste is a kind of, medicated toothpaste is a kind of imagination well, but the effect that really will reach prevention oral pathology needs to do some further investigations.
In prior art, conventional dentifrices is made up of abrasivus, wetting agent, thickening agent, foaming agent, aromatic, water and other additives, and wherein leading composition is all abrasivus, and cleaning action completes primarily of abrasivus.This cleaning mode of life-time service, can make injury of teeth, causes the adverse consequencess such as periodontal inflammation.Active matter sodium fluoride, stannous fluoride, sodium monofluorophosphate, zinc fluoride etc. are added with in toothpaste with fluoride.Fluorine also can have a negative impact to tooth and skeleton while cleaning teeth, dental fluorosis can make permanent teeth be Chalk color to buff, skeletal fluorosis then can destroy skeleton.Anti-inflammation drugs toothpaste on the basis of ordinary toothpaste, adds some antibacterials, as hibitane etc.These medicines generally all have antiphlogistic antibacterial effect, but life-time service easily causes normal flora imbalance in oral cavity.Also have the tooth paste product utilizing ferment enzyme as additive in prior art, but formula is too complicated, causes cost to increase, preparation technology is loaded down with trivial details, and due to additive numerous, have impact on the cleaning action of ferment enzyme itself on the contrary, the cleaning effect of tooth can not be ensured; Some utilizes ferment enzyme as the tooth paste product of additive, ferment toothpaste as described in patent 201410112255.7, it remains in fact the mode adopting abrasivus to clean or to add fluoride and completes and clean one's teeth, the limited use of ferment enzyme, same meeting injury of teeth, causes the adverse consequencess such as periodontal inflammation.
In view of this, special proposition the present invention.
Summary of the invention
The first object of the present invention is to provide a kind of composite enzyme toothpaste, described composite enzyme toothpaste have cleaning effect by force, effectively reduce friction, effectively reduce to adamantine injury, etc. advantage.
The second object of the present invention is the preparation method providing a kind of described composite enzyme toothpaste, and the method technique is simple, and originally can select commercially available convenient source, cost is low, is suitable for large-scale production.
In order to realize above-mentioned purpose of the present invention, spy by the following technical solutions:
A kind of composite enzyme toothpaste, described composite enzyme toothpaste mainly comprises the composition of following mass fraction:
Wetting agent 40%-50%, surfactant 2%-3%, thickening agent 2%-4%, additive 35%-50%, proteolytic enzyme 1%-5%, amylolysis ferment 0.1%-2%, lipase 0.1%-2%, surplus are water.
The present invention does not adopt conventional dentifrices to adopt the form of a large amount of abrasivus (calcium carbonate, calcium hydrogen phosphate, calcium pyrophosphate etc.); do not adopt fluorochemical; antibacterials (hibitane etc.) are not adopted yet; pass through special formulation; give full play to the effect of proteolytic enzyme, amylolysis ferment and lipase, effective cleaning teeth, reduce conventional friction agent to the physical friction of tooth; protection gingiva, and ferment itself can play the effect of anti-inflammation.
Breaks down proteins to most ultimate unit aminoacid, is called complete hydrolysis, will reach the hydrolysis of above-mentioned degree by proteolytic enzyme, being called limitation hydrolysis.The present invention utilizes this principle, removes protein matter residual on oral cavity and tooth.
Amylolysis ferment directly can make amylolysis, is hydrolyzed to glucose.Starch is water insoluble, and glucose is completely water-soluble, and the interpolation of this composition can remove the starchy material remained on oral cavity and tooth, prevents the generation of tartar.
Lipase is the enzyme that a class has multiple catalytic capability, can the hydrolysis of catalysis triglyceride and some other water-insoluble esters, alcoholysis, esterification, transesterification and esters reverse reaction reaction.Lipase removes the fats residuals in oral cavity, reaches cleaning oral cavity, the effect of tooth.
Sweeting agent preferably containing 0.5%-1% in described composite enzyme toothpaste, can select suitable consumption according to taste; Described sweeting agent be preferably in cyclohexylamine sulfonic acid sodium, saccharin sodium one or both, more preferably saccharin sodium.The sweet 300-500 of sweetness ratio sucrose of saccharin sodium doubly, is not decomposed in vivo, is excreted by kidney.
Edible essence preferably containing 1%-2% in described composite enzyme toothpaste, can select the edible essence of suitable taste as required.
Food coloring preferably containing 1%-2% in described composite enzyme toothpaste, can select appropriate color and consumption as required; Described food coloring is preferably food-level titanium dioxide.Food-level titanium dioxide is nontoxic, tasteless, white powder, water insoluble, be insoluble to solvent, be also insoluble to soda acid, stable performance, has whitening effect.
Described wetting agent is one or more in glycerol, sorbitol, xylitol, Polyethylene Glycol, is preferably sorbitol.Sorbitol aqueous solution is sticky shape transparency liquid, has optical activity, slightly sweet taste, has hygroscopicity, can dissolve various metals.
Described surfactant is sodium lauryl sulphate (K
12), one or more in sodium lauryl sulfate, 2-acyl-oxygen base key sodium sulfonate, be preferably sodium lauryl sulphate (K
12).Sodium lauryl sulphate be white or faint yellow powdery, water-soluble, to alkali and hard water insensitive.There is the foaming power of decontamination, emulsifying and excellence.It is a kind of nontoxic anion surfactant.
Described thickening agent is one or more in carboxymethyl cellulose (CMC), Cornu Cervi pectin, hydroxyethyl-cellulose, xanthan gum, guar gum, carrageenin, is preferably carboxymethyl cellulose (CMC).Carboxymethyl cellulose (CMC) odorless, tasteless, nontoxic, be soluble in cold water or its aqueous solution of hot water has the effects such as thickening, film forming, gluing, water tariff collection, colloid protection, emulsifying and suspension.
Described additive is Silica Using for Toothpaste.The feature of Silica Using for Toothpaste has good thixotropy and abrasion resistance.Fall slag problem because its good thixotropy effectively can solve the toothpaste of brushing teeth, meanwhile, because its abrasion resistance coefficient mates with tooth, decrease the wear intensity to tooth, and stable chemical nature, safety.In existing toothpaste industry is produced, most of dalcium biphosphate, precipitated calcium carbonate, aluminium oxide etc. are as filler, these materials exist as just implant at this mostly, and owing to have employed a large amount of phosphides, easily cause the rich phosphorus of water quality, cause secondary environmental pollution, moreover, the wearing coefficient of these materials differs too large with the wearing coefficient of tooth, excessive use can produce damage to tooth.And the selected modulation of wearing coefficient of Silica Using for Toothpaste foundation human teeth forms; And solve toothpaste use time easy conglomeration, fall the problems such as slag, through test prove, it has the wearing coefficient matched with tooth, decreases the wearing and tearing to tooth, adds the whiteness of tooth; And use the toothpaste of Silica Using for Toothpaste to carve in use to form pulpous state rapidly, not easily fall slag, the toothpaste dosage of at every turn brushing teeth is greatly reduced.
Described composite enzyme toothpaste preferably mainly comprises the composition of following mass fraction:
Wetting agent 45%-50%, surfactant 2%-2.5%, thickening agent 2.5%-3.5%, additive 35%-40%, proteolytic enzyme 2%-4%, amylolysis ferment 0.5%-1%, lipase 0.5%-1%, surplus are water;
Described composite enzyme toothpaste preferably mainly comprises the composition of following mass fraction further:
Wetting agent 47.5%, surfactant 2.2%, thickening agent 3%, additive 35%, proteolytic enzyme 3%, amylolysis ferment 1%, lipase 1%, surplus are water.
The preparation method of above-mentioned composite enzyme toothpaste, comprises the steps:
In proportion by each raw material mixing and stirring, obtain described composite enzyme toothpaste.
The method technique is simple, and be suitable for large-scale production, can adopt marketable material, raw material is easy to get, and formula is simple, and cost is low.
Compared with prior art, beneficial effect of the present invention is:
Composite enzyme toothpaste of the present invention does not use abrasivus and fluoride, but by adding protease in toothpaste, lipase, amylolysis ferment, reaches residual fat in cleaning teeth and oral cavity, starch, the effect of protein matter.Ferment class material can also play the effect of antiphlogistic antibacterial, and protection gingiva, reduces the generation of periodontal disease.The preparation method technique of composite enzyme toothpaste of the present invention is simple, and be suitable for large-scale production, can adopt marketable material, raw material is easy to get, and formula is simple, and cost is low.
Detailed description of the invention
Below in conjunction with embodiment, embodiment of the present invention are described in detail, but it will be understood to those of skill in the art that the following example only for illustration of the present invention, and should not be considered as limiting the scope of the invention.Unreceipted actual conditions person in embodiment, the condition of conveniently conditioned disjunction manufacturer suggestion is carried out.Agents useful for same or the unreceipted production firm person of instrument, be and can buy by commercially available the conventional products obtained.
Embodiment 1
A kind of composite enzyme toothpaste, described composite enzyme toothpaste mainly comprises the composition of following mass fraction:
Wetting agent 40%, surfactant 2%, thickening agent 2%, additive 35%, sweeting agent 0.5%, edible essence 1%, food coloring 1%, proteolytic enzyme 1%, amylolysis ferment 0.1%, lipase 0.1%, surplus are water.
Described wetting agent is sorbitol, surfactant is sodium lauryl sulphate (K
12), thickening agent is carboxymethyl cellulose (CMC), additive is Silica Using for Toothpaste, sweeting agent is saccharin sodium, food coloring is food-level titanium dioxide.
Embodiment 2
A kind of composite enzyme toothpaste, described composite enzyme toothpaste mainly comprises the composition of following mass fraction:
Wetting agent 40%, surfactant 3%, thickening agent 4%, additive 35%, sweeting agent 1%, edible essence 2%, food coloring 2%, proteolytic enzyme 5%, amylolysis ferment 2%, lipase 2%, surplus are water.
Described wetting agent is xylitol, surfactant is sodium lauryl sulfate, thickening agent is hydroxyethyl-cellulose, additive is Silica Using for Toothpaste, sweeting agent is cyclohexylamine sulfonic acid sodium, food coloring is food-level titanium dioxide.
Embodiment 3
A kind of composite enzyme toothpaste, described composite enzyme toothpaste mainly comprises the composition of following mass fraction:
Wetting agent 47.5%, surfactant 2.2%, thickening agent 3%, additive 35%, sweeting agent 0.5%, edible essence 1.2%, food coloring 1.5%, proteolytic enzyme 3%, amylolysis ferment 1%, lipase 1%, surplus are water.
Described wetting agent is sorbitol, surfactant is sodium lauryl sulphate (K
12), thickening agent is carboxymethyl cellulose (CMC), additive is Silica Using for Toothpaste, sweeting agent is saccharin sodium, food coloring is food-level titanium dioxide.
Embodiment 4
A kind of composite enzyme toothpaste, described composite enzyme toothpaste mainly comprises the composition of following mass fraction:
Wetting agent 45%, surfactant 2.5%, thickening agent 3.5%, additive 40%, sweeting agent 0.7%, edible essence 1.5%, food coloring 1.2%, proteolytic enzyme 2%, amylolysis ferment 0.5%, lipase 0.5%, surplus are water.
Described wetting agent is Polyethylene Glycol, surfactant is 2-acyl-oxygen base key sodium sulfonate, thickening agent is Cornu Cervi pectin, additive is Silica Using for Toothpaste, sweeting agent is cyclohexylamine sulfonic acid sodium, food coloring is food-level titanium dioxide.
Embodiment 5
A kind of composite enzyme toothpaste, described composite enzyme toothpaste mainly comprises the composition of following mass fraction:
Wetting agent 50%, surfactant 2%, thickening agent 2%, additive 40%, sweeting agent 0.5%, edible essence 1%, food coloring 1%, proteolytic enzyme 1%, amylolysis ferment 0.1%, lipase 0.1%, surplus are water.
Described wetting agent is sorbitol, surfactant is sodium lauryl sulfate, thickening agent is xanthan gum, additive is Silica Using for Toothpaste, sweeting agent is saccharin sodium, food coloring is food-level titanium dioxide.
Embodiment 6
A kind of composite enzyme toothpaste, described composite enzyme toothpaste mainly comprises the composition of following mass fraction:
Wetting agent 40%, surfactant 2%, thickening agent 2.2%, additive 50%, sweeting agent 0.5%, edible essence 1%, food coloring 1%, proteolytic enzyme 2%, amylolysis ferment 0.5%, lipase 0.5%, surplus are water.
Described wetting agent is glycerol, surfactant is 2-acyl-oxygen base key sodium sulfonate, thickening agent is guar gum, additive is Silica Using for Toothpaste, sweeting agent is cyclohexylamine sulfonic acid sodium, food coloring is food-level titanium dioxide.
Embodiment 7
A kind of composite enzyme toothpaste, described composite enzyme toothpaste mainly comprises the composition of following mass fraction:
Wetting agent 40%, surfactant 3%, thickening agent 4%, additive 35%, sweeting agent 1%, edible essence 2%, food coloring 2%, proteolytic enzyme 5%, amylolysis ferment 2%, lipase 2%, surplus are water.
Described wetting agent is xylitol, surfactant is sodium lauryl sulphate (K
12), thickening agent is carrageenin, additive is Silica Using for Toothpaste, sweeting agent is saccharin sodium, food coloring is food-level titanium dioxide.
Embodiment 8
A kind of composite enzyme toothpaste, described composite enzyme toothpaste mainly comprises the composition of following mass fraction:
Wetting agent 45%, surfactant 2%, thickening agent 2.5%, additive 40%, sweeting agent 0.7%, edible essence 1.5%, food coloring 1.5%, proteolytic enzyme 4%, amylolysis ferment 1%, lipase 1%, surplus are water.
Described wetting agent is Polyethylene Glycol, surfactant is sodium lauryl sulfate, thickening agent is carboxymethyl cellulose (CMC), additive is Silica Using for Toothpaste, sweeting agent is cyclohexylamine sulfonic acid sodium, food coloring is food-level titanium dioxide.
Embodiment 9
A kind of composite enzyme toothpaste, described composite enzyme toothpaste mainly comprises the composition of following mass fraction:
Wetting agent 45%, surfactant 2.5%, thickening agent 3.5%, additive 35%, sweeting agent 1%, edible essence 2%, food coloring 2%, proteolytic enzyme 2%, amylolysis ferment 0.5%, lipase 0.5%, surplus are water.
Described wetting agent is Polyethylene Glycol, surfactant is sodium lauryl sulfate, thickening agent is carboxymethyl cellulose (CMC), additive is Silica Using for Toothpaste, sweeting agent is cyclohexylamine sulfonic acid sodium, food coloring is food-level titanium dioxide.
Composite enzyme toothpaste the present invention prepared and other toothpaste of the prior art (wherein comparative example 1 is Chinese board that Uniliver (China) company limited produces excellently adds the white toothpaste with fluoride of strong tooth, comparative example 2 is produced for YUNNAN BAIYAO Group Co., Ltd Herba Menthae Rotundifoliae type medicated toothpaste, comparative example 3 mild mint flavored ferment toothpaste, the comparative example 4 of producing for Lion Corporation be the ferment toothpaste prepared according to patent 201410112255.7 embodiment 5 scheme) carry out result of use and compare, and result is as follows:
Table 1 toothpaste result of use comparative result
As can be seen from Table 1, composite enzyme toothpaste of the present invention, under the prerequisite that carrying out as active component and abrasivus not using fluoride rubs cleans one's teeth, ferment is played one's part to the full, high efficiency cleans one's teeth, cleaning of teeth effect is thorough, and the periodontal caused because of antibacterial or stimulation, not easily appears in life-time service composite enzyme toothpaste of the present invention.
Although illustrate and describe the present invention with specific embodiment, however it will be appreciated that can to make when not deviating from the spirit and scope of the present invention many other change and amendment.Therefore, this means to comprise all such changes and modifications belonged in the scope of the invention in the following claims.
Claims (10)
1. a composite enzyme toothpaste, is characterized in that, described composite enzyme toothpaste mainly comprises the composition of following mass fraction:
Wetting agent 40%-50%, surfactant 2%-3%, thickening agent 2%-4%, additive 35%-50%, proteolytic enzyme 1%-5%, amylolysis ferment 0.1%-2%, lipase 0.1%-2%, surplus are water.
2. a kind of composite enzyme toothpaste according to claim 1, it is characterized in that, also containing the sweeting agent of 0.5%-1% in described composite enzyme toothpaste, described sweeting agent be preferably in cyclohexylamine sulfonic acid sodium, saccharin sodium one or both, more preferably saccharin sodium.
3. a kind of composite enzyme toothpaste according to claim 1, is characterized in that, the edible essence also containing 1%-2% in described composite enzyme toothpaste.
4. a kind of composite enzyme toothpaste according to claim 1, is characterized in that, the food coloring also containing 1%-2% in described composite enzyme toothpaste, described food coloring is preferably food-level titanium dioxide.
5. a kind of composite enzyme toothpaste according to claim 1, is characterized in that, described wetting agent is one or more in glycerol, sorbitol, xylitol, Polyethylene Glycol, is preferably sorbitol.
6. a kind of composite enzyme toothpaste according to claim 1, is characterized in that, described surfactant is one or more in sodium lauryl sulphate, sodium lauryl sulfate, 2-acyl-oxygen base key sodium sulfonate, is preferably sodium lauryl sulphate.
7. a kind of composite enzyme toothpaste according to claim 1, is characterized in that, described thickening agent is one or more in carboxymethyl cellulose, Cornu Cervi pectin, hydroxyethyl-cellulose, xanthan gum, guar gum, carrageenin, is preferably carboxymethyl cellulose.
8. a kind of composite enzyme toothpaste according to claim 1, is characterized in that, described additive is Silica Using for Toothpaste.
9. a kind of composite enzyme toothpaste according to claim 1, is characterized in that, described composite enzyme toothpaste preferably mainly comprises the composition of following mass fraction:
Wetting agent 45%-50%, surfactant 2%-2.5%, thickening agent 2.5%-3.5%, additive 35%-40%, proteolytic enzyme 2%-4%, amylolysis ferment 0.5%-1%, lipase 0.5%-1%, surplus are water;
Described composite enzyme toothpaste preferably mainly comprises the composition of following mass fraction further:
Wetting agent 47.5%, surfactant 2.2%, thickening agent 3%, additive 35%, proteolytic enzyme 3%, amylolysis ferment 1%, lipase 1%, surplus are water.
10. the preparation method of a kind of composite enzyme toothpaste as described in as arbitrary in claim 1-9, is characterized in that, comprise the steps:
In proportion by each raw material mixing and stirring, obtain described composite enzyme toothpaste.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510313488.8A CN104958188A (en) | 2015-06-10 | 2015-06-10 | Composite ferment toothpaste and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510313488.8A CN104958188A (en) | 2015-06-10 | 2015-06-10 | Composite ferment toothpaste and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104958188A true CN104958188A (en) | 2015-10-07 |
Family
ID=54212407
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510313488.8A Pending CN104958188A (en) | 2015-06-10 | 2015-06-10 | Composite ferment toothpaste and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104958188A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107233268A (en) * | 2016-03-23 | 2017-10-10 | 姜培 | One kind release anion ferment energy toothpaste and preparation method thereof |
| CN108420761A (en) * | 2018-04-24 | 2018-08-21 | 凉山绿野山葵有限公司 | A kind of horseradish ferment toothpaste and preparation method thereof |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1031838A (en) * | 1963-09-03 | 1966-06-02 | Warner Lambert Pharmaceutical | Compositions for cleansing the oral cavity |
| GB1033229A (en) * | 1963-09-04 | 1966-06-22 | Iptor Pharmazeutische Praepara | Preparations for the care of the teeth |
| US4082841A (en) * | 1975-10-10 | 1978-04-04 | Lever Brothers Company | Dentifrice |
| CN1190579A (en) * | 1998-03-06 | 1998-08-19 | 曹家鑫 | Enzyme added tooth paste and preparing method thereof |
| CN1366875A (en) * | 2001-10-12 | 2002-09-04 | 天津蓝天集团股份有限公司 | Biological enzyme toothpaste |
| CN1771902A (en) * | 2005-11-04 | 2006-05-17 | 山东师范大学 | Multifunctional health toothpaste and its production process |
| CN1864661A (en) * | 2005-05-20 | 2006-11-22 | 远景生物科技（上海）有限公司 | A highly effective plaque-removing whitening toothpaste and method for making same |
-
2015
- 2015-06-10 CN CN201510313488.8A patent/CN104958188A/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1031838A (en) * | 1963-09-03 | 1966-06-02 | Warner Lambert Pharmaceutical | Compositions for cleansing the oral cavity |
| GB1033229A (en) * | 1963-09-04 | 1966-06-22 | Iptor Pharmazeutische Praepara | Preparations for the care of the teeth |
| US4082841A (en) * | 1975-10-10 | 1978-04-04 | Lever Brothers Company | Dentifrice |
| CN1190579A (en) * | 1998-03-06 | 1998-08-19 | 曹家鑫 | Enzyme added tooth paste and preparing method thereof |
| CN1366875A (en) * | 2001-10-12 | 2002-09-04 | 天津蓝天集团股份有限公司 | Biological enzyme toothpaste |
| CN1864661A (en) * | 2005-05-20 | 2006-11-22 | 远景生物科技（上海）有限公司 | A highly effective plaque-removing whitening toothpaste and method for making same |
| CN1771902A (en) * | 2005-11-04 | 2006-05-17 | 山东师范大学 | Multifunctional health toothpaste and its production process |
Non-Patent Citations (1)
| Title |
|---|
| 苇荭: "洁白健康的牙齿,多彩全效的牙膏——五大功能、十大品牌全方位解析", 《化学清洗》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107233268A (en) * | 2016-03-23 | 2017-10-10 | 姜培 | One kind release anion ferment energy toothpaste and preparation method thereof |
| CN108420761A (en) * | 2018-04-24 | 2018-08-21 | 凉山绿野山葵有限公司 | A kind of horseradish ferment toothpaste and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES2370639T3 (en) | ORAL COMPOSITION CONTAINING ENZYMES THAT HAS IMPROVED STABILITY. | |
| CN1750807B (en) | Anti-sensitivity, anti-caries, anti-staining, anti-plaque, ultra-mild oral hygiene agent | |
| CN101784255B (en) | Oral care strip or band and its use and production method | |
| LU86580A1 (en) | ANTI-SCALE TOOTHPASTE COMPOSITION BASED ON PYROPHOSPHATE, MANUFACTURING METHOD THEREOF AND USE THEREOF | |
| CN106963662B (en) | Color-changing toothpaste for children and preparation method and application thereof | |
| US4812306A (en) | Toothpaste or dental cream composition and method of preparing same | |
| CN101690699A (en) | Teeth-cleaning whitening toothpaste composition | |
| CN103068363B (en) | Means for removing tobacco tars and composition containing same | |
| CN108078802A (en) | A kind of toothpaste and preparation method thereof | |
| US5004596A (en) | Anhydrous toothpaste or dental cream composition | |
| CN111000772A (en) | New use of exocarpium Citri Grandis extract | |
| CN104958188A (en) | Composite ferment toothpaste and preparation method thereof | |
| CN107007503A (en) | A kind of bacteria inhibiting composition and its preparation method and application | |
| TWI396556B (en) | Oral treatment compositions containing anti-adhesion agent, antibacterial agent and incompatible compound | |
| US11723847B2 (en) | Dual component oral composition for enhancing remineralization of teeth | |
| CN103040640A (en) | Antiseptic toothpaste | |
| CN105125417A (en) | Fluoride-free, non-pigment and saccharin-sodium-free micro-foam type edible children toothpaste and preparation method thereof | |
| JP4937583B2 (en) | Oral composition | |
| CN1132567C (en) | Toothpaste | |
| US10813855B2 (en) | Oral care products and methods | |
| CN110279636A (en) | A kind of whitening promoting and tooth-building toothpaste and preparation method thereof | |
| Mason | Dental hygiene | |
| JPS59152317A (en) | Composition for oral cavity | |
| US20240148619A1 (en) | Dual component oral composition for enhancing remineralization of teeth | |
| JP3793625B2 (en) | Powder dentifrice composition |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20151007 |
|
| RJ01 | Rejection of invention patent application after publication |