CN104923185A - 用于清除h-n-大分子病毒的医用吸附树脂 - Google Patents

用于清除h-n-大分子病毒的医用吸附树脂 Download PDF

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CN104923185A
CN104923185A CN201510291604.0A CN201510291604A CN104923185A CN 104923185 A CN104923185 A CN 104923185A CN 201510291604 A CN201510291604 A CN 201510291604A CN 104923185 A CN104923185 A CN 104923185A
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resin
virus
macromolecular
eliminating
adsorption resin
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CN104923185B (zh
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于杰
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Weihai Weigaoyangquan Biological Co ltd
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TIANJIN YANGQUAN MEDICAL DEVICES CO Ltd
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3627—Degassing devices; Buffer reservoirs; Drip chambers; Blood filters
    • A61M1/3633—Blood component filters, e.g. leukocyte filters
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2220/00—Aspects relating to sorbent materials
    • B01J2220/40—Aspects relating to the composition of sorbent or filter aid materials
    • B01J2220/48—Sorbents characterised by the starting material used for their preparation
    • B01J2220/4812—Sorbents characterised by the starting material used for their preparation the starting material being of organic character

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
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  • Life Sciences & Earth Sciences (AREA)
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  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • External Artificial Organs (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

用于清除H-N-大分子病毒的医用吸附树脂，其特征在于：是在树脂碳链中嵌入金属元素的新结构树脂。

Description

用于清除H-N-大分子病毒的医用吸附树脂
技术领域
 本发明属于医用吸附树脂。
背景技术
目前还没有通过血液净化疗法，用于清除血液中H-N-类大分子病毒的医用树脂。
发明内容
本发明是已经获得授权通知的申请号为:201310347458.x,申请日为：2013.08.12，发明名称为：《苯乙烯系树脂的新结构产品，制备方法及其用途》的分案申请，本发明的内容是该申请案中的用途部分分案。
本发明医用吸附树脂，是在苯乙烯系树脂碳链中嵌入金属元素的新结构树脂，嵌入的金属元素是铁离子；采用的苯乙烯系新结构树脂的孔径0-200nm，其中含140-200nm孔径的树脂不低于60%。
本发明树脂可有效的清除患者体内过量的中、大分子毒物，对中分子和中大分子的病毒H-N-在临床验证中获得了很好的效果，对抢救由病毒引发的突发性流行疾病（H1N1，H7N9,SARS)是非常有效的治疗方法和抢救措施。已经有临床病例的个案。
本发明树脂对葡萄膜炎患者血液中的白介素1、6、18,有吸附作用,可以缓解甚至治愈葡萄膜炎疾患。
本发明的树脂可对血液内的过量的炎症因子；白介素、肿瘤坏死因子、甲状旁腺素、内皮素、肾素、血管紧张素、高胰岛素等都有着针对性的吸附清除作用。

Claims (1)

1.用于清除H-N-大分子病毒的医用吸附树脂，其特征在于：是在树脂碳链中嵌入金属元素的新结构树脂，嵌入的金属元素是铁离子；采用的苯乙烯系新结构树脂的孔径0-200nm,其中含140-200nm孔径的树脂不低于60%。
CN201510291604.0A 2013-08-12 2013-08-12 用于清除h‑n‑大分子病毒的医用吸附树脂 Active CN104923185B (zh)

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CN201310347458.XA CN103483487B (zh) 2013-08-01 2013-08-12 苯乙烯系树脂的新结构产品、制备方法及其用途

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CN201510120605.9A Active CN104689804B (zh) 2013-08-12 2013-08-12 用于吸附血液中艾滋病毒分子的苯乙烯系树脂
CN201510291617.8A Pending CN104857015A (zh) 2013-08-12 2013-08-12 用于脱瘾、解毒的苯乙烯系新结构吸附树脂
CN201510156544.1A Active CN104815628B (zh) 2013-08-12 2013-08-12 一种改性苯乙烯—二乙烯苯大孔吸附树脂的用途
CN201510291604.0A Active CN104923185B (zh) 2013-08-12 2013-08-12 用于清除h‑n‑大分子病毒的医用吸附树脂
CN201510291616.3A Pending CN104887700A (zh) 2013-08-12 2013-08-12 用于清除梅毒、性病致病因子的医用吸附树脂
CN201510291618.2A Pending CN104922147A (zh) 2013-08-12 2013-08-12 清除高胆固醇的新结构医用树脂
CN201510291587.0A Pending CN104887699A (zh) 2013-08-12 2013-08-12 用于清除阻碍神经传导因子的医用吸附树脂
CN201510120428.4A Active CN104689803B (zh) 2013-08-12 2013-08-12 用于吸附血液中肝炎病毒的苯乙烯系树脂
CN201510291602.1A Active CN104941607B (zh) 2013-08-12 2013-08-12 用于清除血液中高β2微球蛋白的苯乙烯系树脂吸附剂
CN201510120761.5A Active CN104667897B (zh) 2013-08-12 2013-08-12 用于吸附血液中高内毒素的苯乙烯系树脂

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CN201510291617.8A Pending CN104857015A (zh) 2013-08-12 2013-08-12 用于脱瘾、解毒的苯乙烯系新结构吸附树脂
CN201510156544.1A Active CN104815628B (zh) 2013-08-12 2013-08-12 一种改性苯乙烯—二乙烯苯大孔吸附树脂的用途

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CN201510291618.2A Pending CN104922147A (zh) 2013-08-12 2013-08-12 清除高胆固醇的新结构医用树脂
CN201510291587.0A Pending CN104887699A (zh) 2013-08-12 2013-08-12 用于清除阻碍神经传导因子的医用吸附树脂
CN201510120428.4A Active CN104689803B (zh) 2013-08-12 2013-08-12 用于吸附血液中肝炎病毒的苯乙烯系树脂
CN201510291602.1A Active CN104941607B (zh) 2013-08-12 2013-08-12 用于清除血液中高β2微球蛋白的苯乙烯系树脂吸附剂
CN201510120761.5A Active CN104667897B (zh) 2013-08-12 2013-08-12 用于吸附血液中高内毒素的苯乙烯系树脂

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CN104689804B (zh) * 2013-08-12 2016-03-02 天津市阳权医疗器械有限公司 用于吸附血液中艾滋病毒分子的苯乙烯系树脂
US20180185492A1 (en) * 2015-07-09 2018-07-05 Jie Yu Micro-nano medical adsorbent resin powder material
CN107789691A (zh) * 2016-09-07 2018-03-13 天津市阳权医疗器械有限公司 专用于治疗内毒素血症的一次性使用血液灌流器
CN108031454B (zh) * 2017-12-19 2021-08-13 陈荣胜 具备物理特异选择性的血液净化吸附剂及其制备方法
CN113262762B (zh) * 2021-05-06 2023-04-21 西安蓝深新材料科技股份有限公司 一种血液灌流用吸附材料及其制备方法
CN114085829B (zh) * 2021-11-18 2023-08-11 军事科学院军事医学研究院环境医学与作业医学研究所 一种环境介质中病毒高效富集方法

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CN104941607A (zh) 2015-09-30
CN104815628B (zh) 2017-08-11
CN104941607B (zh) 2017-02-01
CN104815628A (zh) 2015-08-05
CN104689803A (zh) 2015-06-10
CN104923185B (zh) 2017-10-24
CN104887699A (zh) 2015-09-09
CN104689803B (zh) 2016-03-02
CN104887700A (zh) 2015-09-09
CN104689804A (zh) 2015-06-10
CN104922147A (zh) 2015-09-23
CN104689804B (zh) 2016-03-02
CN104667897B (zh) 2016-03-02
CN104667897A (zh) 2015-06-03

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