CN104922602A - Traditional Chinese medicine for treating coronary heart disease combination dyslipidemia - Google Patents
Traditional Chinese medicine for treating coronary heart disease combination dyslipidemia Download PDFInfo
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Abstract
The invention belongs to the technical field of medicine, and particularly relates to traditional Chinese medicine for treating coronary heart disease combination dyslipidemia. The traditional Chinese medicine is composed of, by weight, 11-19 parts of morinda officinalis, 11-19 parts of amomum tsao-ko, eight to 16 parts of fructus amomi, five to 13 parts of bulbiferous stonecrop, two to four parts of caesalpinia cucullata, two to four parts of panus conchatus, eight to 16 parts of radix scrophulariae, eight to 16 parts of codonopsis pilosula, five to 13 parts of root-bark of seguin argyreia, five to 13 parts of parmelia tinctourium, five to 13 parts of radix curcuma, eight to 16 parts of fructus aurantii, eight to 16 parts of fructus lycii and five to 13 parts of radix glycyrrhizae. The traditional Chinese medicine has the effects of tonifying qi and warming yang, dispelling cold and removing stasis and achieving pain or numbness removal and tongmai. The blood lipid level of a patient suffering from the coronary heart disease combination dyslipidemia can be remarkably improved, and the clinical curative effect is remarkable.
Description
Technical field
The invention belongs to medical art, be specifically related to a kind of Chinese medicine for the treatment of coronary artery disease complicated dyslipidemia.
Background technology
Coronary heart disease and coronary atherosclerotic heart disease, mean that coronary atherosclerosis makes that lumen of vessels is blocked, blood supply causes myocardial ischemia for hypoxgia, anoxia and the heart disease that causes.Data is had to show, dyslipidemia and coronary heart disease close, coronary heart disease occurs and harm is increased with serum total cholesterol (TC) level and increase, and high triglyceride (TG) mass formed by blood stasis can cause that low density lipoprotein, LDL (LDL-C) level raises, high density lipoprotein (HDL-C) level reduces.Therefore, blood fat level of sufferers with coronary heart disease is regulated and controled, effectively can control conditions of patients, reduce case fatality rate.
Have not yet to see the medicine being exclusively used in coronary artery disease complicated dyslipidemia.
Summary of the invention
Technical problem to be solved by this invention avoids the weak point existing for above-mentioned prior art, provides a kind of Chinese medicine for the treatment of coronary artery disease complicated dyslipidemia, and this Chinese medicine can significantly improve coronary artery disease complicated dyslipidemia blood lipid, and clinical efficacy is remarkable.
The present invention is achieved through the following technical solutions:
Treat a Chinese medicine for coronary artery disease complicated dyslipidemia, be made up of the Chinese medicine of following weight portion:
Radix Morindae Officinalis 11-19 part, Fructus Tsaoko 11-19 part, Fructus Amomi 8-16 part, Bulbiferous Stonecrop 5-13 part, Radix Zanthoxyli Spinifolii 2-4 part, light leather ear 2-4 part, Radix Scrophulariae 8-16 part, Radix Codonopsis 8-16 part, Cortex Argyreiae Seguinii Radicis 5-13 part, Parmelia saxatilis Ach. 5-13 part, Rhizoma Curcumae Longae 5-13 part, Fructus Aurantii 8-16 part, Fructus Lycii 8-16 part, Radix Glycyrrhizae 5-13 part.
Preferably, the Chinese medicine of above-mentioned treatment coronary artery disease complicated dyslipidemia, is made up of the Chinese medicine of following weight portion:
Radix Morindae Officinalis 13-17 part, Fructus Tsaoko 13-17 part, Fructus Amomi 10-14 part, Bulbiferous Stonecrop 7-11 part, Radix Zanthoxyli Spinifolii 2.5-3.5 part, light leather ear 2.5-3.5 part, Radix Scrophulariae 10-14 part, Radix Codonopsis 10-14 part, Cortex Argyreiae Seguinii Radicis 7-11 part, Parmelia saxatilis Ach. 7-11 part, Rhizoma Curcumae Longae 7-11 part, Fructus Aurantii 10-14 part, Fructus Lycii 10-14 part, Radix Glycyrrhizae 7-11 part.
Preferred, the Chinese medicine of above-mentioned treatment coronary artery disease complicated dyslipidemia, is made up of the Chinese medicine of following weight portion:
Radix Morindae Officinalis 15 parts, Fructus Tsaoko 15 parts, Fructus Amomi 12 parts, Bulbiferous Stonecrop 9 parts, Radix Zanthoxyli Spinifolii 3 parts, light leather 3 parts, ear, Radix Scrophulariae 12 parts, Radix Codonopsis 12 parts, Cortex Argyreiae Seguinii Radicis 9 parts, Parmelia saxatilis Ach. 9 parts, 9 parts, Rhizoma Curcumae Longae, Fructus Aurantii 12 parts, Fructus Lycii 12 parts, 9 parts, Radix Glycyrrhizae.
In each Chinese medicine for the treatment of coronary artery disease complicated dyslipidemia of the present invention:
Bulbiferous Stonecrop bulbil Herba Sedi Linearis, Herba Sedi Bulbiferi, derive from Crassulaceae sengreen Sedumviviparum Sedum bulbiferum Makino, with all herbal medicine.Nature and flavor are pungent, puckery, temperature.Function cold expelling, regulates the flow of vital energy, pain relieving, preventing the attack (or recurrence) of malaria.For abdominal pain due to retention of food, rheumatism is paralysed, malaria.
Radix Zanthoxyli Spinifolii another name Radix Zanthoxyli Planispini, Radix Zanthoxyli Spinifolii, seed of Zanthoxylum armatum DC.(Z.Planispinum Sieb.et Zucc.) root.The root bark of rutaceae Fructus Zanthoxyli Plansipini or root.The whole year can adopt.Acrid in the mouth, warm in nature.Function is dispeled the wind, cold expelling, invigorates blood circulation, pain relieving.Control headache flu, cough, vomit and diarrhoea, rheumatic arthritis, traumatic injury, toothache.
Light leather ear another name purple leather ear is Bai Mo section fungus conchoidal leather ear Panus conchatus (Bull.ex Fr.) Fr. [Agaricus conchatus Bull.ex Fr.; Panus torulosus (Pers.) Fr.var.comchatus Karst.] sporophore.Function wind-evil dispelling and cold-evil expelling; Relaxing muscles and tendons and activating QI and blood in the collateral.Main lumbago and skelalgia; Numb hand and foot; Grain does not relax; Tic of the limbs.
Cortex Argyreiae Seguinii Radicis another name Pueraria lobata, traumatic injury king, rattan Radix Dipsaci, white cattle rattan, flour water bird, carry on the back rattan in vain, root bark or Herb that Flos Calystegiae sepii rattan, Caulis Fibraureae are dicotyledon scammonia section plant Cortex Argyreiae Seguinii Radicis Argyreia seguinii (Le.vl.) Van.ex Levl. [Lettsomia seguinii Levl.].Micro-puckery; Temperature.Enter the heart; Lung meridian.Function qi-supplementing, blood-engendering; Dissipating blood stasis stops blooding.Main blood deficiency is dizzy; Fracture; Hemorrhage due to internal injury
Parmelia saxatilis Ach. another name stone tongue, breast flower, lichens, road Garrick.Derive from lichens Flos Mume clothing section Flos Mume clothing platymiscium lichen Parmelia saxatilis Ach., be used as medicine with thallus.Sweet, cold.Can heat of the diaphragm clearly, diuresis, dissipating phlegm for eliminating goiter, improving eyesight of enriching blood, benefit god increases marrow.
Other medicines record in Chinese Pharmacopoeia 2010 editions 1.
The ratio of above weight proportion is through that science screening obtains, and for especial patient, as serious symptom or mild, fat or modest patient, can the proportioning of amount of corresponding adjustment composition, and increase or reduce being no more than 100%, drug effect is substantially constant.
The weight portion of said medicine, if in units of g, the normally consumption of 1 dose.
The indication of Chinese medicine of the present invention: be used for the treatment of coronary artery disease complicated dyslipidemia.
The taboo item of Chinese medicine of the present invention: the fasting for the treatment of period in a medicine is greasy, raw and cold, the smelling of fish or mutton, irritant and stodgy food.
Coronary artery disease complicated dyslipidemia blood samples of patients is dense, glutinous, solidifying, poly-, is similar to the turbid blood stasis of expectorant in Chinese medicine, can belongs to the category such as " blood stasis syndrome ", " phlegm syndrome ", " BI-syndrome involved the blood vessels ".Accumulate in the dirty YANG QI deficiency of liver,spleen,kidney three and phlegm-damp, qi depression to blood stasis, phlegm and blood stasis, be the pathogenesis basis of primary disease, belong to the card of deficiency in origin and excess in superficiality.Doctor thinks, this card gas, blood, yin, yang are all empty, and based on deficiency of heart-QI, though show as, cold coagulation, the stagnation of QI, expectorant are turbid, blood stasis, but based on blood stasis, therefore should with QI invigorating warming YANG, treating rheumatism arteries and veins for primary treatment scheme.
In Chinese medicine of the present invention, Radix Morindae Officinalis, Fructus Tsaoko, Fructus Amomi warming and recuperating the spleen and kidney, temperature help heart-yang, Bulbiferous Stonecrop, Radix Zanthoxyli Spinifolii, light leather ear dispelling cold by warming the meridian, and spleen is warmed up in Fructus Lycii the kidney invigorating, help Radix Morindae Officinalis altogether, Fructus Tsaoko rouses oneself yang-energy, a surname's venting QI-blood; Radix Scrophulariae, Radix Codonopsis, Parmelia saxatilis Ach., Cortex Argyreiae Seguinii Radicis benefiting qi and nourishing blood grow the heart-yin, Rhizoma Curcumae Longae, the blood stasis dispelling of Fructus Aurantii blood-activating and qi-promoting lead to strongly fragrant, reduce phlegm the chest stuffiness relieving, Radix Glycyrrhizae mend coordinating the actions of various ingredients in a prescription.All medicines share, and play QI invigorating warming YANG, capable stagnant, the treating rheumatism feeling pulse effect of cold expelling altogether.
We's compatibility is reasonable, and all medicines share plays QI invigorating warming YANG, capable stagnant, the treating rheumatism feeling pulse effect of cold expelling altogether.Can significantly improve coronary artery disease complicated dyslipidemia blood lipid, clinical efficacy is remarkable.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further described, so that those skilled in the art more understands the present invention, but does not therefore limit the present invention.
Embodiment 1
Treat a Chinese medicine for coronary artery disease complicated dyslipidemia, each crude drug weight proportion is as follows:
Radix Morindae Officinalis 15g, Fructus Tsaoko 15g Fructus Amomi 12g, Bulbiferous Stonecrop 9g, Radix Zanthoxyli Spinifolii 3g, light leather ear 3g, Radix Scrophulariae 12g, Radix Codonopsis 12g, Cortex Argyreiae Seguinii Radicis 9g, Parmelia saxatilis Ach. 9g, Rhizoma Curcumae Longae 9g, Fructus Aurantii 12g, Fructus Lycii 12g, Radix Glycyrrhizae 9g.
Embodiment 2
Treat a Chinese medicine for coronary artery disease complicated dyslipidemia, each crude drug weight proportion is as follows:
Radix Morindae Officinalis 13-17 part, Fructus Tsaoko 13-17 part, Fructus Amomi 10-14 part, Bulbiferous Stonecrop 7-11 part, Radix Zanthoxyli Spinifolii 2.5-3.5 part, light leather ear 2.5-3.5 part, Radix Scrophulariae 10-14 part, Radix Codonopsis 10-14 part, Cortex Argyreiae Seguinii Radicis 7-11 part, Parmelia saxatilis Ach. 7-11 part, Rhizoma Curcumae Longae 7-11 part, Fructus Aurantii 10-14 part, Fructus Lycii 10-14 part, Radix Glycyrrhizae 7-11 part.
Embodiment 3
Treat a Chinese medicine for coronary artery disease complicated dyslipidemia, each crude drug weight proportion is as follows:
Radix Morindae Officinalis 13 parts, Fructus Tsaoko 17 parts, Fructus Amomi 10 parts, Bulbiferous Stonecrop 11 parts, Radix Zanthoxyli Spinifolii 2.5 parts, light leather 3.5 parts, ear, Radix Scrophulariae 10 parts, Radix Codonopsis 14 parts, Cortex Argyreiae Seguinii Radicis 7 parts, Parmelia saxatilis Ach. 11 parts, 7 parts, Rhizoma Curcumae Longae, Fructus Aurantii 14 parts, Fructus Lycii 10 parts, 11 parts, Radix Glycyrrhizae.
Embodiment 4
Treat a Chinese medicine for coronary artery disease complicated dyslipidemia, each crude drug weight proportion is as follows:
Radix Morindae Officinalis 19 parts, Fructus Tsaoko 11 parts, Fructus Amomi 16 parts, Bulbiferous Stonecrop 5 parts, Radix Zanthoxyli Spinifolii 4 parts, light leather 2 parts, ear, Radix Scrophulariae 16 parts, Radix Codonopsis 8 parts, Cortex Argyreiae Seguinii Radicis 13 parts, Parmelia saxatilis Ach. 5 parts, 13 parts, Rhizoma Curcumae Longae, Fructus Aurantii 8 parts, Fructus Lycii 16 parts, 5 parts, Radix Glycyrrhizae.
Embodiment 5
Treat a Chinese medicine for coronary artery disease complicated dyslipidemia, each crude drug weight proportion is as follows:
Radix Morindae Officinalis 11 parts, Fructus Tsaoko 19 parts, Fructus Amomi 8 parts, Bulbiferous Stonecrop 13 parts, Radix Zanthoxyli Spinifolii 2 parts, light leather 4 parts, ear, Radix Scrophulariae 8 parts, Radix Codonopsis 16 parts, Cortex Argyreiae Seguinii Radicis 5 parts, Parmelia saxatilis Ach. 13 parts, 5 parts, Rhizoma Curcumae Longae, Fructus Aurantii 16 parts, Fructus Lycii 8 parts, 13 parts, Radix Glycyrrhizae.
Carried out clinical pharrnacokinetics experiment to the Chinese medicine for the treatment of coronary artery disease complicated dyslipidemia of the present invention, Details as Follows:
1 data and method
1.1 physical data
Select coronary artery disease complicated dyslipidemia patient 74 example, all with reference to name and the diagnostic criteria of ischemic heart desease, and the diagnostic criteria of Blood Lipid Abnormality in Chinese Adults guideline of prevention and treatment hyperlipemia is made a definite diagnosis.Wherein man 42 example, female 32 example; Age 42-65 years old, year mean age (53.63 ± 0.61); Course of disease 2-14, average course of disease (8.43 ± 0.95) year.Above-mentioned patient is divided into observation group and matched group at random, often organize each 37 examples, two groups of patients are through statistical analysis in sex, age, the course of disease, the state of an illness etc., and difference is all not remarkable, not statistically significant (P>0.05), has comparability.
1.2 Therapeutic Method matched groups adopt the medicines such as nitrate esters medicine, medicament for resisting platelet aggregation, calcium antagonist to carry out conventional therapy.Observation group gives Chinese medicine of the present invention on this basis, prescription: Radix Morindae Officinalis 15g, Fructus Tsaoko 15g Fructus Amomi 12g, Bulbiferous Stonecrop 9g, Radix Zanthoxyli Spinifolii 3g, light leather ear 3g, Radix Scrophulariae 12g, Radix Codonopsis 12g, Cortex Argyreiae Seguinii Radicis 9g, Parmelia saxatilis Ach. 9g, Rhizoma Curcumae Longae 9g, Fructus Aurantii 12g, Fructus Lycii 12g, Radix Glycyrrhizae 9g.Decoction, 1 dose/d, a point morning and evening takes for twice; Within 2 weeks, be 1 course for the treatment of, totally 2 courses for the treatment of, interval 5d between the course for the treatment of.The blood lipid levels such as two groups of patients serums TC, TG, LDL-C, HDL-C are detected respectively before and after treatment.
1.3 statistical analysis adopt SPSS17.0 statistics software to carry out analyzing and processing, and all detection data all adopt x ± S to represent, compare between group and adopt inspection, P<0.05 is that difference has statistical significance.
2 results
Before treatment, the blood lipid levels such as two groups of patients TC, TG, LDL-C, HDL-C are all comparatively similar, there was no significant difference (P>0.05); After treatment terminates, two groups of patient TC, TG, LDL-C levels all have reduction in various degree, the rising in various degree of HDL-C level, observation group patient These parameters is improved particularly remarkable, and concurrent control group front with treatment compares, and all has significant difference (P<0.05).In Table l.
Claims (3)
1. treat a Chinese medicine for coronary artery disease complicated dyslipidemia, be made up of the Chinese medicine of following weight portion:
Radix Morindae Officinalis 11-19 part, Fructus Tsaoko 11-19 part, Fructus Amomi 8-16 part, Bulbiferous Stonecrop 5-13 part, Radix Zanthoxyli Spinifolii 2-4 part, light leather ear 2-4 part, Radix Scrophulariae 8-16 part, Radix Codonopsis 8-16 part, Cortex Argyreiae Seguinii Radicis 5-13 part, Parmelia saxatilis Ach. 5-13 part, Rhizoma Curcumae Longae 5-13 part, Fructus Aurantii 8-16 part, Fructus Lycii 8-16 part, Radix Glycyrrhizae 5-13 part.
2. the Chinese medicine for the treatment of coronary artery disease complicated dyslipidemia according to claim 1, is characterized in that, is made up of the Chinese medicine of following weight portion:
Radix Morindae Officinalis 13-17 part, Fructus Tsaoko 13-17 part, Fructus Amomi 10-14 part, Bulbiferous Stonecrop 7-11 part, Radix Zanthoxyli Spinifolii 2.5-3.5 part, light leather ear 2.5-3.5 part, Radix Scrophulariae 10-14 part, Radix Codonopsis 10-14 part, Cortex Argyreiae Seguinii Radicis 7-11 part, Parmelia saxatilis Ach. 7-11 part, Rhizoma Curcumae Longae 7-11 part, Fructus Aurantii 10-14 part, Fructus Lycii 10-14 part, Radix Glycyrrhizae 7-11 part.
3. the Chinese medicine for the treatment of treatment coronary artery disease complicated dyslipidemia according to claim 2, is characterized in that, be made up of the Chinese medicine of following weight portion:
Radix Morindae Officinalis 15 parts, Fructus Tsaoko 15 parts, Fructus Amomi 12 parts, Bulbiferous Stonecrop 9 parts, Radix Zanthoxyli Spinifolii 3 parts, light leather 3 parts, ear, Radix Scrophulariae 12 parts, Radix Codonopsis 12 parts, Cortex Argyreiae Seguinii Radicis 9 parts, Parmelia saxatilis Ach. 9 parts, 9 parts, Rhizoma Curcumae Longae, Fructus Aurantii 12 parts, Fructus Lycii 12 parts, 9 parts, Radix Glycyrrhizae.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109589401A (en) * | 2019-01-29 | 2019-04-09 | 上海葆颐康医药科技有限公司 | A kind of tcm product and preparation method thereof for treating coronary heart disease |
Citations (2)
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| WO2012020422A1 (en) * | 2010-08-09 | 2012-02-16 | Interdisciplinary School Of Indian System Of Medicine | A novel herbal formulation advocated for the prevention and management of coronary heart disease |
| CN102552793A (en) * | 2012-02-16 | 2012-07-11 | 陈琳 | Chinese medicinal composition for treating unstable angina pectoris derived from aged coronary heart disease |
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2015
- 2015-07-08 CN CN201510396467.7A patent/CN104922602A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012020422A1 (en) * | 2010-08-09 | 2012-02-16 | Interdisciplinary School Of Indian System Of Medicine | A novel herbal formulation advocated for the prevention and management of coronary heart disease |
| CN102552793A (en) * | 2012-02-16 | 2012-07-11 | 陈琳 | Chinese medicinal composition for treating unstable angina pectoris derived from aged coronary heart disease |
Non-Patent Citations (1)
| Title |
|---|
| 张燕辉: "瓜蒌薤白白酒汤治疗冠心病合并血脂异常患者37例临床疗效观察", 《中国民族民间医药》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109589401A (en) * | 2019-01-29 | 2019-04-09 | 上海葆颐康医药科技有限公司 | A kind of tcm product and preparation method thereof for treating coronary heart disease |
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