CN104922381B - Gastric ulcer auxiliary treatment drink and preparation method thereof - Google Patents

Gastric ulcer auxiliary treatment drink and preparation method thereof Download PDF

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CN104922381B
CN104922381B CN201510318514.6A CN201510318514A CN104922381B CN 104922381 B CN104922381 B CN 104922381B CN 201510318514 A CN201510318514 A CN 201510318514A CN 104922381 B CN104922381 B CN 104922381B
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fresh lotus
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李旌
郭岚
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Abstract

The invention discloses a kind of gastric ulcer auxiliary treatment drink and preparation method thereof, active ingredient includes that the raw material of following parts by weight is made:Fresh lotus rhizome section 380~400, fresh lotus rhizome 260~280, fresh yam 180~200, fresh lotus pod 120~140, new lotus leaf 240~250, the fresh lotus seeds 70~80 of belt carcass, honey 360~380.Preparation method includes the following steps:A, new lotus leaf is added water to cook with cold water soak, is concentrated into concentrate;Low-temp storage 48 days~50 days;B, the fresh lotus seeds co-grinding of fresh lotus rhizome section, fresh lotus rhizome, fresh yam, fresh lotus pod, belt carcass dried will be cleaned;C, fermented honey is added in the slurries for obtaining step B;D, the step A concentrates obtained and step the C slurries obtained are mixed, then are sealed by fermentation.The present invention can solve the problem of that the drug of existing treatment gastric ulcer is taken for a long time influences patients ' life quality and service life to human body generation side effect.

Description

Gastric ulcer auxiliary treatment drink and preparation method thereof
Technical field
It is especially a kind of to digestive tract ulcers such as stomach and duodenums the present invention relates to alimentary canal auxiliary treatment technical field Patient has healht-care liquid of auxiliary therapeutic action and preparation method thereof.
Background technology
Canker or peptic ulcer are a kind of common disease of digestive tracts, can betide oesophagus, stomach or duodenum, Stomach-intestinal anastomosis mouth can be betided nearby or in the Meckel diverticulums containing stomach lining, because of gastric ulcer and duodenal ulcer It is most common, therefore general so-called peptic ulcer refers to gastric ulcer and duodenal ulcer.It bursts why it is referred to as digestibility Ulcer is because previously thinking that gastric ulcer and duodenal ulcer are since hydrochloric acid in gastric juice and pepsin form mucous membrane autodigestion , in fact hydrochloric acid in gastric juice and pepsin are one of the main reason for ulcer is formed, and also other reasons can form digestibility Ulcer.The treatment of canker is typically necessary even takes such as ulcerlmin, bismuth agent, 18-BETA-Glycyrrhetinic acid and antibiosis all the life for a long time Element, but curative effect and unstable, and lead to the discomfort of other organs of body, and it is also easy to produce drug resistance, cause other complication.In order to Reduce drug to human body toxic side effect, people begin one's study Chinese medicine treatment peptic ulcer, in numerous Chinese medicine preparations, although production Certain curative effect, but these Chinese medicine preparations are given birth to, or excessively strong or excessively cold, has been not suitable for patient and takes for a long time.Thus need research and development one It is kind without side-effects to human body, and various body organs and the system normal circulation of people can be balanced in treating disease Drink coordinates drug administration, to reduce the side effect that prolonged administration of drugs brings human body.
Invention content
Problem to be solved by this invention is to provide a kind of gastric ulcer auxiliary treatment drink and preparation method thereof, existing to solve There is the drug for the treatment of gastric ulcer to take the problem of generating side effect to human body, influencing patients ' life quality and service life for a long time.
To solve the above-mentioned problems, the technical scheme is that:Its active ingredient packet of this gastric ulcer auxiliary treatment drink The raw material for including following parts by weight is made:Fresh lotus rhizome section 380~400, fresh lotus rhizome 260~280, fresh yam 180~200, fresh lotus Room 120~140, new lotus leaf 240~250, the fresh lotus seeds 70~80 of belt carcass, honey 360~380.
Fresh lotus rhizome section, it is sweet in flavor, puckery, it is mild-natured;Return liver, lung, stomach, constitution is hard, and can dissipate can receive;Work(with astringing to arrest bleeding Effect.Among rhizoma nelumbinis convergence and can promoting blood circulation, hemostasis and without staying the disadvantage of the stasis of blood.Rhizoma nelumbinis can be used for treating haematemesis, bleeding from five sense organs or subcutaneous tissue etc. it is a variety of go out Blood trouble.Rhizoma nelumbinis is longer than hemostasis, and can dissipate the stasis of blood.It for bleeding from five sense organs or subcutaneous tissue, hemoptysis, spits blood, have blood in stool, hematuria and woman uterine bleeding, have to lose blood Hemostasis person is most appropriate.
Fresh lotus rhizome, sweet in flavor, cool in nature, main bowl spares is burnt, reposes, benefiting energy.Energy clearing heat and promoting fluid, cooling blood and hemostasis, scattered blood stasis.Ripe use Tepor can strengthen the spleen and stomach, antidiarrheal, beneficial blood, myogenic.Bowl spares is reposed, and all kinds of diseases and ailments are removed.Informal dress makes light of one's life by commiting suicide resistance to old, promotes longevity.Help ten Two passages through which vital energy circulates vim and vigour, the flat heat of sun in vivo cross Sheng, hyperactivity of fire.It lays one's heart bear kidney, thick stomach, solid essence, strengthening the bones and muscles, qi-restoratives damage, sharp knowledge, and remove Cold-dampness, only the splenic diarrhea protracted dysentery, the diseases such as non-menstrual period Massive Bleeding of woman.Eat excessive, fine motion gas raw.It smashs to pieces and cooks congee food with rice, make one Strong, steamed wheaten foods might as well.The dry puckery people that defecates cannot eat it.Lotus is the fruit of beneficial spleen.
New lotus leaf, nature and flavor are bitter, put down, Return liver, spleen, stomach, the heart channel of Hang-Shaoyin.There are the work(such as clearing summer-heat and damp, sending up the lucid yang, cooling blood and hemostasis Effect.Medicinal extract piece is made in the alkaloid and flavones of middle extraction, plays the role of reducing blood lipid and norcholesterol after clinical application, has been used for controlling Treat the illnesss such as hyperlipidemia, obesity, fatty liver.
Chinese yam property is sweet, and taste is flat, returns spleen, lung, kidney channel, tonifying spleen nourishing the stomach, engender liquid and benefic lung, the puckery essence of kidney tonifying, has nourishing strong, helps and disappear Change, hold back abnormal sweating, the effect of antidiarrheal, cures mainly insufficiency of the spleen diarrhoea, cough due to deficiency of the lung, gastric ulcer are quenched one's thirst, oliguria frequency, seminal emission, women is under And dyspeptic chronic enteritis.
Lotus pod, also known as:Lotus receptacle is the ripe holder of nymphaeaceae plant lotus.Bitter is puckery wet, returns the liver channel of foot-Jueyin, point Blood, controls metrorrhagia, menorrhalgia, blood under threatened abortion, abdominal pain due to blood stasis, postpartum retention of afterbirth, bloody flux, blood strangury, hemorrhoid rectal prolapse, and skin is wet Sore.Band medicine is controlled to dissipate the stasis of blood, it can preventing gastric ulcer.
Lotus seeds, sweet in flavor, puckery, mild-natured, returns spleen, kidney, the heart channel of Hang-Shaoyin.Has tonifying spleen and stopping diarrhea, stop-band, the puckery essence of kidney-nourishing, the work(of mental-tranquilization Effect.Lotus it is sweet in flavor, temperature and property is puckery, report the gas of clear virtue, obtain the taste of sowing and reaping, be the fruit of spleen.Soil is the mother of vigour, and mother-qi was both With, body fluid coordinates, and god is spontaneous, regard long it is resistance to old, with its beginning.Former times rules breakdown of the normal physiological coordination between the heart and the kidney by men, and internal lesion caused by overexertion gonorrhoea has the lotus seeds that clear away heart-fire Drink;Bushing kidney, benefiting essence-blood have auspicious lotus ball, all obtain this reason.
Honey, it is sweet in flavor;It is mild-natured;Converge to the spleen channel, stomach, lung channel, large intestine channel;Harmonizing the spleen and stomach;Relieving spasm to stop pain;It moistens the lung and relieve the cough;Profit Intestines defaecation;Moisturizing myogenic;Removing toxic substances.The empty pain of main gastral cavity abdomen;Xeropulmonary cough;Dry constipation of intestines;Hot eyes;Aphtha;Unhealing ulcer;Rubella scabies Itch;Scald;Rhagadia manus et pedis.Treat taste-blindness rate.
To solve the above-mentioned problems, technical scheme of the present invention further includes:The preparation side of this gastric ulcer auxiliary treatment drink Method includes the following steps:
A, by 240 parts~250 parts of new lotus leaf cold water soak 50 minutes~be filtered dry after sixty minutes, it is put into new lotus leaf weight 3 times of water of amount decocts, and decocts three times, and decocting time is 1.3 hours~1.5 hours three times, the decocting liquid that will be collected into three times Merge, it is 1.1~1.2 concentrates that relative density is concentrated at a temperature of 40 °C~50 DEG C;It is deposited at a temperature of being placed in -15 °C~-8 °C It puts 48 days~50 days;
B, 380 parts~400 parts of the fresh lotus rhizome section dried, 260 parts~280 parts of fresh lotus rhizome, 180 parts~200 will be cleaned The fresh yam of part, 120 parts~140 parts of fresh lotus pod, 70 parts~80 parts of the fresh lotus seeds of belt carcass are mixed to form mixture, are put into crushing In machine, the water co-grinding of 3.2~3.4 times of said mixtures is added into slurries, filtering, after filtering, in the slurries The diameter dimension of particle is between the mesh of 800 mesh~850;The water is mineral water or passes through the processed tap water of water factory;
C, the slurries that step B is obtained are added to 360 parts~380 parts of honey be put into container at a temperature of 25 °C~35 °C Fermentation 30 days, the gas during fermentation by container pressure when excessive are released;It is sealed fermentation 145 days~160 days, sealing later Fermentation temperature is 20 °C~30 °C;
D, the step A concentrates obtained and step the C slurries obtained are mixed, then are sealed by fermentation 60 days~90 days; Fermentation temperature is 20 °C~30 °C.The gastric ulcer auxiliary treatment drink so prepared, can be dilute according to personal taste and custom 50 times~10 times are released when beverage is drunk, taste acid is refreshing, such as drinks fruit juice, and the amount of drinking per Japan's gastric ulcer auxiliary treatment drink is 20 millis It rises, not more than 30 millimeters.
Using fresh lotus rhizome section and new lotus leaf as monarch drug in a prescription in this gastric ulcer auxiliary treatment drink, the pure and impure yin-nourishing dampness removing of cool blood is eliminated Ulcer, supplemented by the fresh lotus seeds of fresh lotus rhizome, belt carcass, fresh yam, nourishing stomach and spleen, while lean gas is supported, the sending up the lucid yang of new lotus leaf improves The immunity of organisms of people, promotes various metabolic functions, and honey sterilization disappears, and has not only reconciled hundred medicines, but also nourishing Johnson & Johnson, adjusts taste to mend The foundation of acquired constitution;We select the major part of lotus plant as primary raw material, and the entire plant of lotus flower is considered by ancient Chinese medicine The five-element give birth to the plant for balance of going out, and clearly without trembling with fear, mend and dry, five elements balancing, and be derived from nature food materials, can be long-term to eat for medicine It takes, the pharmacological property of no other Chinese medicine preparations is excessively strong excessively cold and generates harmful effect to body.
This method uses based on fresh plant lotus, is fermented into small molecule, the various metabolism in coordinated balance body, including sugared generation It thanks, while also decomposing drug residue, reduce the side effect of drug generated to human body;Special small big fresh lotus rhizome etc. is broken Grain, suspends in a liquid, beautiful and appetite has not only been increased, but also contain certain cellulose, to help the stomach of ulcers to disappear Helping digestion object, helps toxin expelling;Lotus leaf after cooking, can increase it is scorching, be conducive to human body, Chinese medicine be referred to as " fiery poison ", in special low temperature Lower storage is more than certain time, and with solution " fiery poison ", so that warm but not dry, suitable human body is largely taken for a long time.
Specific implementation mode
The embodiment of the present invention is described in further detail below:
Embodiment one:
Its active ingredient of this gastric ulcer auxiliary treatment drink includes that the raw material of following parts by weight is made:Fresh lotus rhizome section 380, Fresh lotus rhizome 260, fresh yam 190, fresh lotus pod 120, new lotus leaf 250, the fresh lotus seeds 75 of belt carcass, honey 370.
The preparation method of this gastric ulcer auxiliary treatment drink, includes the following steps:
A, 250 parts of new lotus leaf being filtered dry after sixty minutes with cold water soak, 3 times of water for being put into new lotus leaf weight decocts, It decocting three times, decocting time is followed successively by 1.5 hours, 1.4 hours, 1.3 hours three times, and the decocting liquid being collected into three times is merged, It is 1.1 concentrates that relative density is concentrated at a temperature of 40 °C~45 °C;It is stored 49 days at a temperature of being placed in -15 °C~-12 °C;B, To clean 380 parts of the fresh lotus rhizome section dried, 260 parts of fresh lotus rhizome, 190 parts of fresh yam, 120 parts of fresh lotus pod, 75 parts The fresh lotus seeds of belt carcass are mixed to form mixture, are put into pulverizer, and the water co-grinding for adding 3.3 times of said mixtures is slurried Liquid, the diameter dimension of the particle in slurries is between the mesh of 800 mesh~850;The water is mineral water;C, the slurry for obtaining step B Liquid 370 parts of honey of addition are put into container and ferment 30 days at a temperature of 25 °C~35 °C, when during fermentation that container pressure is excessive Gas release;It is sealed fermentation 145 days later, it is 20 °C~30 °C to be sealed by fermentation temperature;D, the concentration for obtaining step A The slurries mixing that liquid and step C are obtained, then be sealed by fermentation 80 days;Fermentation temperature is 20 °C~30 °C.So prepare Diabetes auxiliary treatment drink can dilute 50 times~10 times when beverage is drunk according to personal taste and custom, taste acid is refreshing, Fruit juice is such as drunk, the amount of drinking per Japan Diabetes auxiliary treatment drink is 20 milliliters, not more than 30 millimeters;It is also used as down Leavening when secondary preparation uses, and in step C, 0.5% to 1% this drink of slurries and honey total amount is added.
Embodiment two:
Its active ingredient of this gastric ulcer auxiliary treatment drink includes that the raw material of following parts by weight is made:Fresh lotus rhizome section 400, Fresh lotus rhizome 270, fresh yam 180, fresh lotus pod 140, new lotus leaf 245, the fresh lotus seeds 80 of belt carcass, honey 360.
The preparation method of this gastric ulcer auxiliary treatment drink, includes the following steps:
A, 245 parts of new lotus leaf being filtered dry with cold water soak after 55 minutes, 3 times of water for being put into new lotus leaf weight decocts, It decocting three times, decocting time is followed successively by 1.5 hours, 1.4 hours, 1.3 hours three times, and the decocting liquid being collected into three times is merged, It is 1.2 concentrates that relative density is concentrated at a temperature of 45 DEG C~50 DEG C;It is stored 48 days at a temperature of being placed in -12 °C~-8 °C;B, To clean 400 parts of the fresh lotus rhizome section dried, 270 parts of fresh lotus rhizome, 180 parts of fresh yam, 140 parts of fresh lotus pod, 80 parts The fresh lotus seeds of belt carcass are mixed to form mixture, are put into pulverizer, and the water co-grinding for adding 3.2 times of said mixtures is slurried Liquid, filtering, after filtering, the diameter dimension of the particle in the slurries is between the mesh of 800 mesh~850;The water is to pass through water factory Processed tap water;C, the slurries that step B is obtained are added to 360 parts of honey be put into container at a temperature of 25 °C~35 °C Fermentation 30 days, the gas during fermentation by container pressure when excessive are released;It is sealed fermentation 160 days later, is sealed by fermentation temperature Degree is 20 °C~30 °C;D, the step A concentrates obtained and step the C slurries obtained are mixed, then are sealed by fermentation 90 days; Fermentation temperature is 20 °C~30 °C.The diabetes auxiliary treatment drink so prepared, can be dilute according to personal taste and custom 50 times~10 times are released when beverage is drunk, taste acid is refreshing, such as drinks fruit juice, and the amount of drinking per Japan Diabetes auxiliary treatment drink is 20 millis It rises, not more than 30 millimeters;Leavening when being also used as preparing next time uses, and in step C, slurries and honey is added 0.5% to 1% this drink of total amount.
Embodiment three:
Its active ingredient of this gastric ulcer auxiliary treatment drink includes that the raw material of following parts by weight is made:Fresh lotus rhizome section 390, Fresh lotus rhizome 280, fresh yam 200, fresh lotus pod 130, new lotus leaf 240, the fresh lotus seeds 70 of belt carcass, honey 380.
The preparation method of this gastric ulcer auxiliary treatment drink, includes the following steps:
A, 240 parts of new lotus leaf being filtered dry after sixty minutes with cold water soak, 3 times of water for being put into new lotus leaf weight decocts, It decocting three times, decocting time is followed successively by 1.5 hours, 1.4 hours, 1.3 hours three times, and the decocting liquid being collected into three times is merged, It is 1.15 concentrates that relative density is concentrated at a temperature of 43 °C~46 DEG C;It is stored 50 days at a temperature of being placed in -15 °C~-10 °C; B, will clean dry 390 parts of fresh lotus rhizome section, 280 parts of fresh lotus rhizome, 200 parts of fresh yam, 130 parts of fresh lotus pod, 70 parts The fresh lotus seeds of belt carcass be mixed to form mixture, be put into pulverizer, add the water co-grindings of 3.4 times of said mixtures at Slurries, filtering, after filtering, the diameter dimension of the particle in the slurries is between the mesh of 800 mesh~850;The water is mineral water; It C, slurries that step B is obtained are added to 380 parts of honey are put into container and ferment 30 days at a temperature of 25 °C~35 °C, the fermentation phase Between gas of container pressure when excessive is released;It is sealed fermentation 160 days later, it is 20 °C~30 °C to be sealed by fermentation temperature; D, the step A concentrates obtained and step the C slurries obtained are mixed, then are sealed by fermentation 60 days;Fermentation temperature is 20 °C ~30 °C.The diabetes auxiliary treatment drink so prepared, according to personal taste and custom, can dilute 50 times~10 times and work as Beverage is drunk, and taste acid is refreshing, such as drinks fruit juice, and the amount of drinking per Japan Diabetes auxiliary treatment drink is 20 milliliters, not more than 30 millimeters;Leavening when being also used as preparing next time uses, in step C, be added the 0.5% of slurries and honey total amount to 1% this drink.
Embodiment one to embodiment three clinical observation on the therapeutic effect.
Case-data:All cases meet what digestive endoscopy branch of Chinese Medical Association in 2003 worked out《Chronic gastritis Endoscopic classification grade scale and treatment tentative opinion》Diagnostic criteria.Clinical symptoms:The upper abdomen of prolonged and repeated generation is full Bored, pain, belch, dry, noisy, pantothenic acid, gastroscope prompt have superficial gastric ulcer or rotten to the corn gastric ulcer or reflux stomach to burst Ulcer is diagnosed as patients w ith peptic ulcer disease 132, and experiment is participated in informed consent.
Two groups are randomly divided into, test group 70 awards drug therapy, and drug is LE Wei Tab, Ha Yaoji selected by drug therapy The smart product of medicine three is breathed out by group, on the basis of drug therapy, gives embodiment one to the drink of embodiment three, according to personal taste and Custom dilutes 50 times~10 times for oral administration, 20 milliliters of daily drink amounts;Control group 62, awards drug therapy, and selected drug is stomach Speed is happy, and the smart product of medicine three is breathed out by Harbin Pharmaceutical Group.
Treat 2 years time limits, 2 years observation periods.Two groups of patients are 76 people of male, and 56 people of women, the age is at 16 to 50 years old Between, test group average age 34 years old, control group average age 35 years old, treatment group anticipates with control group comparison, no statistical difference Justice(P > 0.05).
Treatment standard:Reference《Chinese medicine Clinical Researches of New Drugs guideline》It drafts.It cures:Clinical symptoms disappear, gastroscope inspection It looks into ulcer and surrounding inflammation all disappears, therapeutic index>95%;Effectively:Clinical symptoms are obviously improved, gastrocopy ulcer area 50% or more is reduced, therapeutic index >=30%;In vain:Clinical symptoms are without improvement, and gastrocopy ulcer surface is reduced not as good as 50%, curative effect Index<30%.
Table 1 is two groups of patient test's results contrasts
From table 1 it follows that test group cure rate is 88.57%, patient's recovery from illness, completely without adverse reaction, in 2 years Without recurrence, effective percentage is 11.43%, and patient is obviously improved upper abdomen in 30 days expires bored, pain, belch, dry, noisy, pantothenic acid Etc. symptoms, without recurrence in 2 years, the total effective rate of the sum of cure rate and effective percentage has reached 98%.Control group cure rate is 30.64%, effective percentage is 37.09%, inefficiency 32.26%.It is substantially better than control group to the therapeutic effect of visible test group. Illustrate that drink obtained by this method has significant curative effect to auxiliary treatment gastric ulcer.
Acute toxicity test:Larger dose and taken compared with long-term therapy, to the growth of rat without notable toxicity, to the brain of rat, The inspection of the chip forms such as the heart, liver, kidney has no that overt toxicity damage changes, and experiment is realized, by a process for preparing the stomaches come to burst Ulcer auxiliary treatment drink toxicity is very small.

Claims (1)

1. a kind of preparation method of gastric ulcer auxiliary treatment drink, it is characterised in that:Its active ingredient by following parts by weight original Material is made:Fresh lotus rhizome section 380~400, fresh lotus rhizome 260~280, fresh yam 180~200, fresh lotus pod 120~140, new lotus leaf 240~250, the fresh lotus seeds 70~80 of belt carcass, honey 360~380;
Include the following steps:
A, by 240 parts~250 parts of new lotus leaf cold water soak 50 minutes~be filtered dry after sixty minutes, the 3 of new lotus leaf weight are put into Water again decocts, and decocts three times, and decocting time is 1.3 hours~1.5 hours three times, and the decocting liquid being collected into three times is merged, It is 1.1~1.2 concentrates that relative density is concentrated at a temperature of 40 DEG C~50 DEG C;48 are stored at a temperature of being placed in -15 DEG C~-8 DEG C It~50 days;
B, will clean 380 parts~400 parts of the fresh lotus rhizome section dried, 260 parts~280 parts of fresh lotus rhizome, 180 parts~200 parts Fresh yam, 120 parts~140 parts of fresh lotus pod, 70 parts~80 parts of the fresh lotus seeds of belt carcass are mixed to form mixture, are put into pulverizer In, the water co-grinding of 3.2~3.4 times of said mixtures is added into slurries, is filtered, after filtering, in the slurries The diameter dimension of grain is between the mesh of 800 mesh~850;The water is mineral water or passes through the processed tap water of water factory;
It C, slurries that step B is obtained are added to 360 parts~380 parts of honey are put into container and ferment at a temperature of 25 DEG C~35 DEG C 30 days, the gas during fermentation by container pressure when excessive was released;It is sealed fermentation 145 days~160 days later, is sealed by fermentation Temperature is 20 DEG C~30 DEG C;
D, the step A concentrates obtained and step the C slurries obtained are mixed, then are sealed by fermentation 60 days~90 days;Fermentation Temperature is 20 DEG C~30 DEG C.
CN201510318514.6A 2015-06-11 2015-06-11 Gastric ulcer auxiliary treatment drink and preparation method thereof Expired - Fee Related CN104922381B (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1954698A (en) * 2005-10-28 2007-05-02 周怀志 Health-care food for regulating gastrointestinal tract function and its preparation process
CN102860478A (en) * 2012-07-08 2013-01-09 梁荫健 Canned Chinese yam and lotus root cake

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1954698A (en) * 2005-10-28 2007-05-02 周怀志 Health-care food for regulating gastrointestinal tract function and its preparation process
CN102860478A (en) * 2012-07-08 2013-01-09 梁荫健 Canned Chinese yam and lotus root cake

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