CN104921947B - Medical or health care product hard capsule mixed filling system and its control method - Google Patents

Medical or health care product hard capsule mixed filling system and its control method Download PDF

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Publication number
CN104921947B
CN104921947B CN201510232576.5A CN201510232576A CN104921947B CN 104921947 B CN104921947 B CN 104921947B CN 201510232576 A CN201510232576 A CN 201510232576A CN 104921947 B CN104921947 B CN 104921947B
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station
capsule
medicament
injection
medical
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CN104921947A (en
Inventor
贾毅
何福银
朱光耀
刘树天
汤红新
栾国利
王平
葛永龙
赵丹宇
刘金丹
唐欣
庞煜磊
周鹏飞
赵泰
孙国臣
王关波
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JINWAN GROUP CO Ltd DANDONG
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JINWAN GROUP CO Ltd DANDONG
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Abstract

The present invention relates to a kind of medical or health care product hard capsules to mix fill system and its control method, main control unit receives the fluid injection station signal of detection unit acquisition, output end is connected with the control circuit of the control circuit of main motor, the control circuit of vacuum pump and execution unit respectively, the mechanical turntable of the output axis connection capsule liquid injection system of main motor;Method are as follows: the container of corresponding station is prepared enough into required medicament;Each equipment starting;Mechanical turntable separates capsule body, the cap in module hole in dispensing station;If detecting that capsule body exists in module, mechanical turntable fortune does intermittently staying in fluid injection station and note solid or semisolid station, realizes the injection of corresponding medicament;Mechanical turntable completes the function of each station through inspection rejects position, gluing position, compression position, finished product guiding and mold cleaning station.The present invention is reequiped using existing system, realizes the mixed filling of various medicaments, is realized the suspension mixed injection of liquid and is sealed, saves a large amount of equipment and update cost.

Description

Medical or health care product hard capsule mixed filling system and its control method
Technical field
The present invention relates to a kind of medical or health care product capsule mixing filling technique, specifically a kind of medical or health cares Product mix fill system and its control method with hard capsule.
Background technique
Domestic production capsule is broadly divided into two major classes at present: 1) hard capsule: solid or semisolid is filled in hard rubber It is made in capsule;2) soft capsule: oil-based liquid is closed in soft capsule without the liquid mixing suspension of dissolution to capsule material In.
It is big with the investment of health care our factory with soft capsule fill liquid pharmaceutical factory, need to put into flexible glue Tibetan household slave when producing soft capsule Producing line and bottle placer, and hard Capsules filling machine need to be only purchased with hard Capsules fill liquid.
Soft capsule single cannot produce in production, during producing soft capsule, soft capsule and it is filling will be simultaneously It carries out, technique and complex procedures, high production cost.
If it is considered that the process for completing above-mentioned complexity using hard capsule stowage unit, then existing hard capsule filling system Equipment is unable to satisfy complicated technique requirement, and system is needed to rectify and improve.
Summary of the invention
It single cannot be produced in production for soft capsule in the prior art, technique and complex procedures, production cost The deficiencies of high, the technical problem to be solved in the present invention is to provide the medical or health care product ebonites that a kind of low cost, process simplify Capsule mixing fill system and its control method.
In order to solve the above technical problems, the technical solution adopted by the present invention is that:
Medical or health care product hard capsule mixed filling system of the invention, including main control unit, main motor, vacuum pump, Detection unit and execution unit, wherein main control unit receives the fluid injection station signal of detection unit acquisition, main control unit Output end be connected respectively with the control circuit of the control circuit of main motor, the control circuit of vacuum pump and execution unit, it is main The output shaft of motor connects the mechanical turntable of capsule liquid injection system by intermittent box.
Also there is human and machine interface unit, carry out both-way communication connection with main control unit.
The execution unit includes fluid injection control solenoid valve, note solid or semisolid control solenoid valve and the control of interior gluing Solenoid valve is respectively arranged in the power pipeline of fluid injection, note cream and interior glue stations.
The power pipeline has air pressure pump, is connected to by pneumatic pipeline with the pneumatic input port of each metering pump, each The output end of metering pump passes through piping connection to each liquid injecting mouth, each note cream mouth and each interior coating nozzle respectively.
Mechanical turntable includes multiple stations, respectively dispensing station, detection station, fluid injection station, note solid or semisolid Station, gluing station, compresses station, finished product guiding station and mold cleaning station at inspection rejects station, and mechanical turntable is in main motor And in each station intermittently staying under the action of intermittent box, the device being equipped in each station realizes corresponding function.
The detection unit includes at least four road sense channels, detects the signal in place of at least four capsules respectively;Fluid injection Device has at least four reservoir channels;Infusing cream device has at least four note cream channels.
The control method of medical or health care product hard capsule mixed filling system of the invention the following steps are included:
Device power, system initialization;
Corresponding station is selected according to production needs, and the container of corresponding station is prepared enough into required medicament;
Main control unit controls vacuum pump startup;Start metering pump, air pressure pump;
Main control unit control main motor starting, rotates mechanical turntable after vacuum pump stable operation;
In dispensing station, machinery selects and recommends fork and the capsule in capsule hopper is sent into mechanical turntable upper module hole, using true Sky pump negative pressure separates capsule body, the cap in module hole;
Main motor control turntable turns to detection station, by whether having capsule body in detection unit detection module hole;
If detecting that capsule body exists in module, mechanical turntable is run to fluid injection station and note solid or semisolid work Intermittently staying is done in position, starts the solenoid valve of injection device on corresponding station, and the device being equipped in each station realizes corresponding medicine The injection of agent;
Mechanical turntable continues to run, clear through inspection rejects station, gluing station, compression station, finished product guiding station and mold The function of each station is completed in science and engineering position, realizes a medicament stowing operation.
If detection unit does not detect the capsule body in module hole, on corresponding station, the solenoid valve of injection device is not Starting, without injecting the operation of medicament.
The container of corresponding station is prepared enough into required medicament are as follows: dose liquid in the injection device container of corresponding fluid injection station Medicament doses paste medicament, pellet medicament, water-honeyed pill medicament or piece in the injection device container of note solid or semisolid station Agent.
Glue, i.e. the gluing electromagnetism of the corresponding glue stations of the main control unit timing controlled station are carried out in gluing station Valve, which is opened, carries out glue.
The invention has the following beneficial effects and advantage:
1. the present invention is reequiped using existing hard Capsules solid or semisolid fill system, realize various The mixed filling of medicament, including the filling process that should could be completed in soft capsule fill system, to original hard Capsules The transformation that system carries out equipment component is just able to satisfy technique requirement, realizes the suspension mixed injection of liquid and seals, saves A large amount of equipment updates cost.
2. the sealing technology of hard Capsules is changed to internal sealed by external seal formula for the first time by the present invention, eliminate outer close Seal strip has lacked sealing joint strip bonding process in production, has saved work efficiency and cost.
3. the present invention by main motor control a mechanical turntable can realize the fluid injection to hard Capsules, infuse cream, The injection for injecting all kinds of dosage forms such as pellet, water-honeyed pill or tablet substantially increases the production efficiency of filling product.
Detailed description of the invention
Fig. 1 is present system block diagram;
Fig. 2 is control method flow chart of the present invention;
Fig. 3 is motor control schematic diagram in the present invention;
Fig. 4 is fluid injection control principle drawing in the present invention;
Fig. 5 is that cream control principle drawing is infused in the present invention;
Fig. 6 is fluid injection and note cream solenoid valve wiring diagram in the present invention;
Fig. 7 is that capsule detection principle diagram is lacked in the present invention.
Specific embodiment
The present invention is further elaborated with reference to the accompanying drawings of the specification.
As shown in Figure 1, present invention one kind medical or health care product hard capsule mixed filling system, including main control unit, Main motor, vacuum pump, detection unit and execution unit, wherein main control unit receives the fluid injection station letter of detection unit acquisition Number, the control with the control circuit of main motor, the control circuit of vacuum pump and execution unit respectively of the output end of main control unit Circuit processed is connected, and the output shaft of main motor connects the mechanical turntable of capsule liquid injection system by intermittent box.
In the present invention, main control unit uses PLC (Siemens, CPU224XP), main motor (Tianjin speed reducer factory, OL90S/4BRE20ME, 1:11.57 motor 415V 1.1KW) output axis connection capsule liquid injection system mechanical turntable, work as master When electric motor starting, drives mechanical turntable to turn to each station and carry out intermittently staying.In the present embodiment, vacuum pump (Siemens Nahsi Nurse 2BV2061-ONC02-2P;415V 1.45KW) use negative-pressure adsorption function, will select and recommend fork be sent into module hole in capsule body, Cap separation.Detection unit includes at least four road sense channels, and the present embodiment is four tunnels, and each road is all made of optic fibre detector as inspection Element is surveyed, whether the capsule body for detecting capsule particle has been admitted in lower module hole.Electric control theory figure such as Fig. 3,4 institutes Show.
As shown in fig. 6, execution unit includes fluid injection control solenoid valve, note solid or semisolid control solenoid valve and interior painting Glue controls solenoid valve, is respectively arranged in the power pipeline of fluid injection, note cream and interior glue stations.Each solenoid valve in execution unit Movement is opened and closed under the control of main control unit, completes fluid injection, note cream, note pellet, water filling in corresponding station coupled system Honeyed bolus, note tablet and and gluing operation.Wherein, note cream control principle drawing is as shown in Figure 5.
Power pipeline has air pressure pump, is connected to by pneumatic pipeline with the pneumatic input port of each metering pump, each metering The output end of pump passes through respective line respectively and is connected to each liquid injecting mouth, each note cream mouth and each interior coating nozzle.
As shown in fig. 7, detection unit includes at least four road sense channels, the present embodiment is using optoelectronic switch as detection member Part detects (scarce capsule) signal in place of at least four capsules respectively;Priming device has at least four reservoir channels;Infuse cream device With at least four note cream channels.
In the present embodiment, liquid injecting mouth, note cream mouth and interior coating nozzle are four, the capsule in corresponding four lower module holes Body, each liquid injecting mouth, note cream mouth pass through respective line respectively and are connected with the delivery outlet of metering pump, and four liquid injecting mouths use one Metering pump.
Mechanical turntable includes multiple stations, respectively dispensing station, detection station, fluid injection station, note solid or semisolid Station, gluing station, compresses station, finished product guiding station and mold cleaning station at inspection rejects station, and mechanical turntable is in main motor And in each station intermittently staying under the action of intermittent box, the device being equipped in each station realizes corresponding function.Wherein send Station, inspection rejects station, compression station, finished product guiding station and the corresponding device of mold cleaning station pass through mechanical structure and control Its completion acted.
Also there is human and machine interface unit, carry out both-way communication connection with main control unit.Man-machine interface uses touch screen (Siemens TP170B 7), staff can directly operate on the screen, and parameter setting and monitoring are modified in interface needed for calling Equipment running status.
As shown in Fig. 2, medical or health care product hard capsule mixed filling system the control method of the present invention includes following step It is rapid:
Device power, system initialization;
Corresponding station is selected according to production needs, and the container of corresponding station is prepared enough into required medicament;
Main control unit controls vacuum pump startup;Start metering pump, air pressure pump;
Main control unit control main motor starting, rotates mechanical turntable after vacuum pump stable operation;
In dispensing station, machinery selects and recommends fork and the capsule in capsule hopper is sent into mechanical turntable upper module hole, using true Sky pump negative pressure separates capsule body, the cap in module hole;
Main motor control turntable turns to detection station, by whether having capsule body in detection unit detection module hole;
If detecting that capsule body exists in module, mechanical turntable is run to fluid injection station and note solid or semisolid work Intermittently staying is done in position, starts the solenoid valve of injection device on corresponding station, and the device being equipped in each station realizes corresponding medicine The injection of agent;
Mechanical turntable continues to run, clear through inspection rejects station, gluing station, compression station, finished product guiding station and mold The function of each station is completed in science and engineering position, realizes a medicament stowing operation.
If detection unit does not detect the capsule body in module hole, on corresponding station, the solenoid valve of injection device is not Starting, without injecting the operation of medicament.
In order to adapt to the needs of production, before system starting, the container of corresponding station is prepared enough into required medicament, according to glue The dosage form of capsule product doses liquid preparation in the injection device container of corresponding fluid injection station, in note solid or semisolid station Injection device container in dose paste medicament, pellet medicament, water-honeyed pill medicament or tablet, it can realize the note of single formulation Enter, the mixing filling, fluid injection and the mixing filling for infusing cream of mixing filling, fluid injection and the water-honeyed pill of fluid injection and pellet also may be implemented And fluid injection and the mixing of tablet are filled.
The method of the present invention further includes glue step, carries out glue, i.e. the main control unit timing controlled work in gluing station The gluing solenoid valve of the corresponding glue stations in position, which is opened, carries out glue, to guarantee the glue-spread of the fitting sealing of gluing operating point.
In the present embodiment, after equipment starts and initializes, main control unit, that is, PLC first controls vacuum pump startup, and 2 seconds After start main motor, starting air pressure pump and metering pump (can individually manually boot and also be opened by controlling program in main control unit It is dynamic), rotate mechanical turntable by main motor operation start, under the action of intermittent box, mechanical turntable does interval in each station It stops;In dispensing station, machinery selects and recommends fork and is respectively fed to capsule every four in capsule hopper in four module holes for one group, Capsule body, cap in module hole are separated using vacuum pump negative pressure, i.e., capsule body is placed in lower module hole, capsule cap is placed in upper mold In block hole;Main motor control turntable turns to detection station (detection of 4 paths), whether determines in lower module hole (4 paths) There is capsule body, exists if detecting capsule body in lower module hole, when turntable is run to fluid injection station, solenoid valve control metering Pump (the present embodiment is pumped using HighPower) pushes in liquid or lotion injection capsule body.HighPower pump is equivalent to cylinder, solenoid valve control Gas source is opened, and HighPower pump is acted, and is connected on liquid container on HighPower pump.Otherwise, it is detected in lower module hole if detected There is no then solenoid valves not to work for capsule body, works without fluid injection, and liquid can inject in HighPower pump conduit (HighPower pump conduit band Have function of measuring), it therefore, can accurate quantitative analysis injection liquid or lotion;After completing fluid injection, mechanical turntable goes to note solid or half Solid station carries out corresponding at this time if capsule product needs to infuse cream, note pellet, water filling honeyed bolus or note tablet in the station The injection of medicament, then inspection rejects station, rejects underproof capsule, then goes to gluing station, to guarantee the set of gluing operating point The glue-spread of sealing is closed, glue is coated in the inside of capsule cap by the present invention by coating nozzle, then carries out capsule compressing station Body, cap, which fasten, compresses operation, exports finished capsule product through finished product guiding station, and carry out cleaning operation in module cleaning station, with Guarantee the smooth of next circulation process.
If capsule product is not required to fluid injection, without the container in fluid injection station for interior filling medicament, priming device is motionless Make, mechanical turntable is still by the suitable operation for turning to next bit and carrying out other stations.Similarly if being not required to injection cream, pellet, water Honeyed bolus or tablet, then without inserting corresponding medicament in the container of solid or semisolid station.In the present invention, to send work Position, inspection rejects station compress the operation of station, finished product guiding station and mold cleaning station by completing by mechanical device.
The present invention for the first time should be in soft capsule using the realization of existing hard Capsules solid or semisolid fill system The liquid injection process that liquid injection system could be completed, the transformation for carrying out equipment component to original hard Capsules system are just able to satisfy work Skill requirement realizes the suspension mixed injection of liquid and carries out interior sealing.

Claims (4)

1. a kind of control method of medical or health care product hard capsule mixed filling system, it is characterised in that the following steps are included:
Device power, system initialization;
Corresponding station is selected according to production needs, and the container of corresponding station is prepared enough into required medicament;
Main control unit controls vacuum pump startup;Start metering pump, air pressure pump;
Main control unit control main motor starting, rotates mechanical turntable after vacuum pump stable operation;
In dispensing station, machinery selects and recommends fork and the capsule in capsule hopper is sent into mechanical turntable upper module hole, utilizes vacuum pump Negative pressure separates capsule body, the cap in module hole;
Main motor control turntable turns to detection station, by whether having capsule body in detection unit detection module hole;
If detecting that capsule body exists in module, mechanical turntable runs to fluid injection station and note solid or semisolid station and does Intermittently staying starts the solenoid valve of injection device on corresponding station, and the device being equipped in each station realizes corresponding medicament Injection;
Mechanical turntable continues to run, and through inspection rejects station, gluing station, compresses station, finished product guiding station and mold cleaning work The function of each station is completed in position, realizes a medicament stowing operation.
2. the according to claim 1 medical or health care product control method of hard capsule mixed filling system, it is characterised in that: If detection unit does not detect the capsule body in module hole, the solenoid valve of injection device does not start on corresponding station, no Carry out the operation of injection medicament.
3. the according to claim 1 medical or health care product control method of hard capsule mixed filling system, it is characterised in that: The container of corresponding station is prepared enough into required medicament are as follows: liquid preparation is dosed in the injection device container of corresponding fluid injection station, It infuses in the injection device container of solid or semisolid station and doses paste medicament, pellet medicament, water-honeyed pill medicament or tablet.
4. the according to claim 1 medical or health care product control method of hard capsule mixed filling system, it is characterised in that: Gluing station carry out glue, i.e. the gluing solenoid valve of the corresponding glue stations of the main control unit timing controlled station open into Row glue.
CN201510232576.5A 2015-05-07 2015-05-07 Medical or health care product hard capsule mixed filling system and its control method Active CN104921947B (en)

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4656066A (en) * 1982-12-20 1987-04-07 Warner-Lambert Company Apparatus and method for sealing capsules
JP2004351033A (en) * 2003-05-30 2004-12-16 ▲高▼田 ▲寛▼治 Method and device for producing uneven millicapsule and microcapsule
CN101721313A (en) * 2009-12-16 2010-06-09 丹东金丸集团有限公司 Program control full-automatic capsule filling machine
CN203303349U (en) * 2013-06-13 2013-11-27 海门市新港医药科技有限公司 Powder capsule filling machine
CN204766541U (en) * 2015-05-07 2015-11-18 丹东金丸集团有限公司 Medical or for health products mixed filling system of ebonite bag

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030194428A1 (en) * 2002-04-10 2003-10-16 Miller Frederick H. Process for encapsulating multi-phase, multi-compartment capsules

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4656066A (en) * 1982-12-20 1987-04-07 Warner-Lambert Company Apparatus and method for sealing capsules
JP2004351033A (en) * 2003-05-30 2004-12-16 ▲高▼田 ▲寛▼治 Method and device for producing uneven millicapsule and microcapsule
CN101721313A (en) * 2009-12-16 2010-06-09 丹东金丸集团有限公司 Program control full-automatic capsule filling machine
CN203303349U (en) * 2013-06-13 2013-11-27 海门市新港医药科技有限公司 Powder capsule filling machine
CN204766541U (en) * 2015-05-07 2015-11-18 丹东金丸集团有限公司 Medical or for health products mixed filling system of ebonite bag

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