CN104906429A - Cereal dietary fiber composition - Google Patents
Cereal dietary fiber composition Download PDFInfo
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- CN104906429A CN104906429A CN201510367943.2A CN201510367943A CN104906429A CN 104906429 A CN104906429 A CN 104906429A CN 201510367943 A CN201510367943 A CN 201510367943A CN 104906429 A CN104906429 A CN 104906429A
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Abstract
The invention belongs to the field of medicines, and discloses a cereal dietary fiber composition which is prepared from the following raw materials as active components in parts by weight: 20 parts of millet, 25 parts of corn, 18 parts of sorghum, 16 parts of aletris pauciflora, 15 parts of Indian rorippa herb, 20 parts of evergreen mucuna stems, 18 parts of cleistocalyx operculatus and15 parts of pandanus tectorius. The invention further discloses a preparation method which comprises steps of boiling with water, concentrating, performing alcohol precipitation, performing spray-drying or powdering, and mixing. The invention further discloses an application of the cereal dietary fiber composition in preparing healthcare products with a blood fat reduction function.
Description
Technical field
The present invention relates to pharmaceutical preparation, be specifically related to a kind of grain dietary fiber composition and method of making the same and application.
Background technology
Current domestic clinical conventional fat regulation medicine has Statins and Bei Te class, occupies an leading position with statins.Though Statins effectively can reduce serum cholesterol level, such medicine occurs relevant with fatefulue rhabdomyolysis, when particularly blood fat reducing is not up to standard, improves dosage and easily causes muscle changes; And the occurrence probability of rhabdomyolysis increases especially greatly when share with fibrate.In addition, the main component of some curative effect domestic good medicine fat regulation medicine is from Monas cuspurpureus Went (a kind of fungal microbe), and the natural statins in fact also containing suitable dosage, their safety also should be subject to medical attention.For this reason, need to develop the needs that more lipid-regulation medicines safely and effectively meet clinical treatment.Prevalence is high, and relapse rate height is the main feature of hyperlipidemia condition, the fat reducing health product of a kind of effective and safe of market in urgent need.
Summary of the invention
Goal of the invention: in order to solve the problem, the object of the present invention is to provide a kind of grain dietary fiber composition and method of making the same and application.
Technical scheme: the object of the invention is by following scheme realize:
A kind of grain dietary fiber compositions, the active component contained by it is prepared from by following raw materials in part by weight proportioning: Semen setariae 20 parts, Semen Maydis 25 parts, Sorghum vulgare Pers. 18 parts, Herba Aletridis Khasianae 16 parts, Indian Rorippa Herb 15 parts, Radix Seu Caulis Mucunae Sempervirentis 20 parts, Flos Cleistocalycis Operculati 18 parts, Pandanus tectorius 15 parts.
Described grain dietary fiber compositions, preparation method step is: get in above-mentioned corn Semen setariae, Semen Maydis, sorghum material feeding parcher, the bake and parch time is 5 minutes, and temperature is 80 DEG C, and bake and parch is to parching completely; Raw material good for bake and parch is sent into pulverizer, uses 40 eye mesh screens to pulverize, obtain corn powder for subsequent use; Separately get Herba Aletridis Khasianae, Indian Rorippa Herb, Radix Seu Caulis Mucunae Sempervirentis, Flos Cleistocalycis Operculati, the merging of Pandanus tectorius medical material, decoct with water twice, collecting decoction, being concentrated into 65 DEG C of relative densities is 1.10-1.20, adds ethanol, stirs, make alcohol content by volume percentage calculation reach 65-85%, leave standstill, filter, filtrate reduced in volume to 65 DEG C relative density is 1.20-1.30 and reclaims ethanol, by concentrated solution spraying dry, pulverize, mix with corn powder, pack and get final product.
Described grain dietary fiber compositions, in medical material preparation method, decocting condition is: amount of water is the 8-12 times amount of medical material weight for the first time, decocts 1-2h, and second time amount of water is the 6-10 times amount of medical material weight, decocts 1-2h.
Described grain dietary fiber compositions, in medical material preparation method, spray drying condition is: inlet temperature is 90-110 DEG C, and leaving air temp is 60-90 DEG C, and temperature of charge is 60-90 DEG C, and atomizing pressure is 0.2-0.5 MPa, and spray velocity is 1-10ml/s.
Described grain dietary fiber compositions reduces the application in blood fat health product in preparation.
Herba Aletridis Khasianae is Liliaceae Aletris plant Herba Aletridis Khasianae Aletris lanuginosa Bur.et Franch., with all herbal medicine.Autumn gathers, and cleans and dries.Tonify deficiency arresting sweating, hemostasis.For the empty hyperhidrosis of body, neurasthenia, hemoptysis of pulmonary tuberculosis, night sweat.
Indian Rorippa Herb is Cruciferae annual herb plant, eliminates the phlegm, cough-relieving.For chronic bronchitis.Antihypertensive diuretic, cooling blood for hemostasis.For dizziness, hypertension, urine heat is puckery unfavorable, hematuria, metrorrhagia leukorrhagia.The present invention is with all herbal medicine.
Radix Seu Caulis Mucunae Sempervirentis is pulse family Mucuna plant evergreen mucuna Mucuna sempervirens Hemsl., is used as medicine with root, stem and leaf.The whole year can adopt, and dries respectively.Blood circulation promoting and blood stasis dispelling, expelling wind and removing dampness, dredge the meridian passage.For traumatic injury, rheumatalgia, numbness, stimulate the menstrual flow, amenorrhea.The present invention is with all herbal medicine.
Flos Cleistocalycis Operculati is the alabastrum of myrtle water father-in-law.Latin name: Cleistocalyx operculatus (Roxb.) Merr.EtPerry, at the beginning of by the end of May to 6 month, pluck the spray with alabastrum, drench with water, stacking 3-5 days, alabastrum is come off naturally, shine to three one-tenth do, pile vexed 1-2 days again and shine again, later solarization 1 day, vexed 1 day, stay after doing, the remaining branch stalk of well sifted.Eliminating summer-heat from the exterior, drying, it is stagnant to disappear, anti-inflammatory anti-itch.
Pandanus tectorius, Classification system Pandanus tectorius Sol., Pandanaceae Pandanus, cold, fever, pain of eying covetously; Leaf bud can control rotten foot; Fruit can tonifying the spleen and stomach, reinforcing premodial qi, alcoholic intoxication. and cure mainly liver-heat asthenic fire, cirrhotic ascites, heatstroke etc., the present invention is used as medicine with root.
Beneficial effect: from theory of Chinese medical science, Herba Aletridis Khasianae, Indian Rorippa Herb are monarch drug, and Radix Seu Caulis Mucunae Sempervirentis, Flos Cleistocalycis Operculati are ministerial drug, and Pandanus tectorius is adjuvant, full side's heat-clearing and toxic substances removing, dyspepsia and intestinal stasis relieving, then with grain dietary fiber compatibility, for hyperlipidemia condition.
Detailed description of the invention
Form by the following examples, foregoing of the present invention is described in further detail again, but this should be interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to following example, all technology realized based on foregoing of the present invention all belong to scope of the present invention.
Embodiment 1: get Semen setariae 20g, Semen Maydis 25g, Sorghum vulgare Pers. 18g, Herba Aletridis Khasianae 16g, Indian Rorippa Herb 15g, Radix Seu Caulis Mucunae Sempervirentis 20g, Flos Cleistocalycis Operculati 18g, Pandanus tectorius 15g, preparation method step is: get in above-mentioned corn Semen setariae, Semen Maydis, sorghum material feeding parcher, the bake and parch time is 5 minutes, temperature is 80 DEG C, and bake and parch is to parching completely; Raw material good for bake and parch is sent into pulverizer, uses 40 eye mesh screens to pulverize, obtain corn powder for subsequent use; Separately get Herba Aletridis Khasianae, Indian Rorippa Herb, Radix Seu Caulis Mucunae Sempervirentis, Flos Cleistocalycis Operculati, the merging of Pandanus tectorius medical material, decoct with water twice, collecting decoction, being concentrated into 65 DEG C of relative densities is 1.10-1.20, adds ethanol, stirs, make alcohol content by volume percentage calculation reach 65-85%, leave standstill, filter, filtrate reduced in volume to 65 DEG C relative density is 1.20-1.30 and reclaims ethanol, by concentrated solution spraying dry, pulverize, mix with corn powder, pack and get final product.
Embodiment 2: grain dietary fiber compositions of the present invention reduces the pharmacodynamic study of blood fat
Laboratory animal: Kunming mouse, male, body weight 18-22g, Shanghai Slac Experimental Animal Co., Ltd. provides, production licence: SCXK (Shanghai) 2007-0005.
Experimental agents: prepare grain dietary fiber compositions by the preparation method of upper embodiment 1, obtains finished product 10 and wraps.Specification: 10g/ wraps (being equivalent to containing crude drug 10g)
Dosage: then press Mice Body restatement, low dosage, middle dosage and high dose are respectively 5g crude drug amount/kg, 10g crude drug amount/kg and 20g crude drug amount/kg.
Positive drug Zhibituo, by Chengdu buchu nine, great pharmaceutical factory produces, and lot number is 1205212, specification: every dress 0.24g.Patient uses generally each 5, every day 2 times, i.e. people's consumption per day 2.4g, and being equivalent to every 20g mice consumption is 2.4*0.0026=0.00624g, and calculate by per kilogram mice, namely positive drug group gives diabetes pill 0.312g/kg.
High lipid food: 10% yolk powder, 1.2% cholesterol, 10% Adeps Sus domestica, 78% normal feedstuff.
Main agents: T-CHOL (TC), triglyceride (TG), highly dense low lipoprotein cholesterol (HDL-C) and low density lipoprotein, LDL (LDL-C) measure test kit, Beijing Zhong Sheng bio-engineering corporation product.
Experimentation: select healthy mice 60, separates 10 at random as normal group, and all the other 50 mices, raise with high lipid food, normal water, modeling 14d, obtains model group.After model causes, be divided into 5 groups at random: model group, high dose group, middle dosage group, low dose group, positive drug zhibituo group, wherein 3 dosage groups, zhibituo groups are by above-mentioned dosage gastric infusion, Normal group and model group to the water of same volume, every morning 1 time, continuous 30d, get each Mus TC.TG of hematometry, HDL-C, LDL-C, each group of data represent with means standard deviation, carry out t test between group.The results are shown in Table 1
Table 1. grain dietary fiber compositions of the present invention is on the impact (n=10) of Experimental Hyperlipemia Mouse Blood ester level
Note: compare * p<0.05**<0.01 with model group; △ <0.05 △ △ <0.01 is compared with zhibituo group
Conclusion: each dosage group of grain dietary fiber compositions of the present invention can reduce Experimental Hyperlipemia Mouse Blood ester level, has reduction blood fat.
Claims (5)
1. a grain dietary fiber compositions, it is characterized in that, the active component contained by it is prepared from by following raw materials in part by weight proportioning: Semen setariae 20 parts, Semen Maydis 25 parts, Sorghum vulgare Pers. 18 parts, Herba Aletridis Khasianae 16 parts, Indian Rorippa Herb 15 parts, Radix Seu Caulis Mucunae Sempervirentis 20 parts, Flos Cleistocalycis Operculati 18 parts, Pandanus tectorius 15 parts.
2. grain dietary fiber compositions as claimed in claim 1, it is characterized in that, preparation method step is: get above-mentioned corn Semen setariae, Semen Maydis, sorghum material send in parcher, the bake and parch time is 5 minutes, and temperature is 80 DEG C, and bake and parch is to parching completely; Raw material good for bake and parch is sent into pulverizer, uses 40 eye mesh screens to pulverize, obtain corn powder for subsequent use; Separately get Herba Aletridis Khasianae, Indian Rorippa Herb, Radix Seu Caulis Mucunae Sempervirentis, Flos Cleistocalycis Operculati, the merging of Pandanus tectorius medical material, decoct with water twice, collecting decoction, being concentrated into 65 DEG C of relative densities is 1.10-1.20, adds ethanol, stirs, make alcohol content by volume percentage calculation reach 65-85%, leave standstill, filter, filtrate reduced in volume to 65 DEG C relative density is 1.20-1.30 and reclaims ethanol, by concentrated solution spraying dry, pulverize, mix with corn powder, pack and get final product.
3. grain dietary fiber compositions as claimed in claim 2, it is characterized in that, in medical material preparation method, decocting condition is: first time amount of water be the 8-12 times amount of medical material weight, decoct 1-2h, second time amount of water is the 6-10 times amount of medical material weight, decocts 1-2h.
4. grain dietary fiber compositions as claimed in claim 2, it is characterized in that, in medical material preparation method, spray drying condition is: inlet temperature is 90-110 DEG C, leaving air temp is 60-90 DEG C, temperature of charge is 60-90 DEG C, and atomizing pressure is 0.2-0.5 MPa, and spray velocity is 1-10ml/s.
5. grain dietary fiber compositions is reducing the application in blood fat health product as claimed in claim 1.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106237127A (en) * | 2016-06-29 | 2016-12-21 | 完美（中国）有限公司 | Corn fiber powder and production method thereof and purposes |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101366475A (en) * | 2008-09-12 | 2009-02-18 | 奥生平 | Various grains composite rice with steady quality and preparation method thereof |
| CN101449773A (en) * | 2007-11-28 | 2009-06-10 | 天津市中英保健食品有限公司 | Novel dietotherapy porridge and production technique thereof |
| CN101548740A (en) * | 2008-03-31 | 2009-10-07 | 王兆国 | Minor cereal rice and production process thereof |
| CN102960728A (en) * | 2012-12-12 | 2013-03-13 | 夏明华 | Dietetic therapy health maintenance composition |
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- 2015-06-28 CN CN201510367943.2A patent/CN104906429A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101449773A (en) * | 2007-11-28 | 2009-06-10 | 天津市中英保健食品有限公司 | Novel dietotherapy porridge and production technique thereof |
| CN101548740A (en) * | 2008-03-31 | 2009-10-07 | 王兆国 | Minor cereal rice and production process thereof |
| CN101366475A (en) * | 2008-09-12 | 2009-02-18 | 奥生平 | Various grains composite rice with steady quality and preparation method thereof |
| CN102960728A (en) * | 2012-12-12 | 2013-03-13 | 夏明华 | Dietetic therapy health maintenance composition |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106237127A (en) * | 2016-06-29 | 2016-12-21 | 完美（中国）有限公司 | Corn fiber powder and production method thereof and purposes |
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