CN104888017A - Medicine for treating hepatitis B - Google Patents

Medicine for treating hepatitis B Download PDF

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Publication number
CN104888017A
CN104888017A CN201510339730.9A CN201510339730A CN104888017A CN 104888017 A CN104888017 A CN 104888017A CN 201510339730 A CN201510339730 A CN 201510339730A CN 104888017 A CN104888017 A CN 104888017A
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parts
herba
medicine
radix
herb
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王萧
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Abstract

The invention discloses a medicine for treating hepatitis B. The medicine comprises raw materials in parts by weight as follows: 20-30 parts of vietnamese sophora roots, 20-30 parts of stringy stonecrop herb, 20-30 parts of Indian buead, 10-20 parts of szechwan chinaberry fruit, 5-10 parts of lalang grass rhizomes, 10-20 parts of Chinese angelica, 20-30 parts of virgate wormwood herb, 20-30 parts of spreading hedyotis herb, 10-20 parts of corydalis yanhusuo, 3-8 parts of fortune eupatorium herb, 8-15 parts of medicated leaven, 10-20 parts of Chinese gentian, 5-15 parts of barbed skullcap herb, 6-12 parts of Chinese brake herb, 10-20 parts of rice-grain sprout, 3-9 parts of Chinese alangium roots, 10-20 parts of pubescent holly roots, 5-15 parts of saxifrage and 10-20 parts of Japanese cayratia herb. The medicine is low in treatment cost, easy to absorb and good in curative effect, takes effect quickly, can treat both symptom and root causes, does not have toxic or side effects and has a good curative effect on hepatitis B.

Description

A kind of medicine for the treatment of hepatitis B
Technical field
The present invention relates to a kind of medicine for the treatment of hepatitis B, belong to technical field of Chinese medicines.
Background technology
Hepatitis B is caused by hepatitis B virus (HBV), based on liver inflammatory pathological changes, and can cause a kind of disease of multiple organ injury.Hepatitis B is widely current in countries in the world, and main infringement child and person between twenty and fifty, small number of patients can be converted into liver cirrhosis or hepatocarcinoma.Therefore, it has become the worldwide disease of serious threat human health, a kind of disease that Ye Shi China current popular is the most extensive, hazardness is the most serious.Hepatitis B, without certain epizootic modeling, all can be fallen ill throughout the year, but belong to distributes more.Hepatitis B sickness rate is in the trend obviously increased in recent years.Hepatitis B pathogenesis is complicated, and symptom is obstinate, and delay is difficult, thus very big to the health hazard of the mankind.At present, the treatment of Western medicine to hepatitis B does not have breakthrough achievement, and mainly still rely on the Drug therapys such as interferon, vidarabine, thymosin, side effect is larger and costly, once relapse rate is high after drug withdrawal.The treatment of the traditional Chinese medical science to hepatitis B has advantageous advantage, thus market exists the Chinese medicine of a lot for the treatment of hepatitis B, but its therapeutic effect is not remarkable, and treatment cycle is long, easily recurs.So people are to effective treatment hepatitis B and the Chinese medicine had no side effect exists very large demand.
Summary of the invention
For problems of the prior art, the invention provides a kind of medicine for the treatment of hepatitis B.This pharmaceutical formulation is scientific and reasonable, effective to treating hepatitis B, and medical expense is low, short treating period, and has no side effect.
The present invention is by the following technical solutions:
A kind of medicine for the treatment of hepatitis B, it is characterized in that, it is made up of the crude drug of following weight portion: Radix Sophorae Tonkinensis 20-30 part, Herba Sedi 20-30 part, Poria 20-30 part, Fructus Toosendan 10-20 part, Rhizoma Imperatae 5-10 part, Radix Angelicae Sinensis 10-20 part, Herba Artemisiae Scopariae 20-30 part, Herba Hedyotidis Diffusae 20-30 part, Rhizoma Corydalis 10-20 part, Herba Eupatorii 3-8 part, Massa Medicata Fermentata 8-15 part, Radix Gentianae 10-20 part, Herba Scutellariae Barbatae 5-15 part, Herba Pteridis Multifidae 6-12 part, Fructus Setariae Germinatus 10-20 part, Radix Alangii 3-9 part, Radix Ilicis Pubescentis 10-20 part, Herba Saxifragae 5-15 part, Herba Cayatiae Japonicae 10-20 part.
Preferably, the medicine of described treatment hepatitis B is made up of the crude drug of following weight portion: Radix Sophorae Tonkinensis 25 parts, Herba Sedi 25 parts, Poria 20-30 part, Fructus Toosendan 15 parts, Rhizoma Imperatae 8 parts, Radix Angelicae Sinensis 15 parts, Herba Artemisiae Scopariae 25 parts, Herba Hedyotidis Diffusae 25 parts, Rhizoma Corydalis 15 parts, Herba Eupatorii 6 parts, Massa Medicata Fermentata 12 parts, Radix Gentianae 15 parts, Herba Scutellariae Barbatae 10 parts, Herba Pteridis Multifidae 9 parts, Fructus Setariae Germinatus 15 parts, Radix Alangii 6 parts, Radix Ilicis Pubescentis 15 parts, Herba Saxifragae 10 parts, Herba Cayatiae Japonicae 15 parts.
The preparation method of medicine of the present invention is as follows:
(1) take above-mentioned formula ratio material medicine according to quantity, add 800-1000ml cold water soak wherein after 1 hour, first to burn to boiling slow fire boiling again 30 minutes with intense fire, filter to obtain 1 filtered juice;
(2) continuing to add water 500ml decoction to seething with excitement latter 25 minutes in filtering residue, filtering to obtain 2 filtered juices;
(3) 1,2 filtered juice is merged heating is concentrated into 400ml.
The usage of medicine of the present invention and consumption: decocting is oral, a side is potion, potion on the one, one day twice, sooner or later within 1 hour after meal, respectively takes 200ml.10 days 1 courses for the treatment of, general 3-5 can cure a course for the treatment of, and patient with severe symptoms 6-8 can cure a course for the treatment of.
The pharmacological action of formula of the present invention is as follows:
Radix Sophorae Tonkinensis: bitter, cold.Attach to the lung and stomach meridians.There is heat-clearing and toxic substances removing, effect of detumescence sore-throat relieving.
Herba Sedi: sweet in the mouth, light, cool in nature.Return liver, gallbladder, small intestine meridian.There is dampness removing jaundice eliminating, effect of heat-clearing and toxic substances removing.
Poria: sweet in the mouth, light, property is put down.GUIXIN, lung, spleen, kidney channel.There is promoting diuresis to eliminate damp pathogen, spleen invigorating, effect of mind calming.
Fructus Toosendan: bitter, cold.Return liver, small intestinal, urinary bladder channel.There is soothing the liver expelling the heat-evil, promoting the circulation of QI to relieve pain, effect of parasite killing.
Rhizoma Imperatae: sweet, cold.Return lung, stomach, urinary bladder channel.There is cooling blood for hemostasis, effect of clearing away heat and promoting diuresis.
Radix Angelicae Sinensis: warm in nature, sweet in the mouth is pungent.GUIXIN, liver, spleen channel.There is benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturize effect of laxation.
Herba Artemisiae Scopariae: bitter in the mouth, pungent, cold nature.Return spleen, stomach, liver, gallbladder meridian.There is eliminating damp-heat, effect of promoting the function of the gallbladder to alleviate jaundice.
Herba Hedyotidis Diffusae: mildly bitter flavor, cold in nature.Stomach, large intestine, small intestine meridian.There is heat-clearing and toxic substances removing, effect that dampness removing is treating stranguria.
Rhizoma Corydalis: pungent, bitter, temperature.Return liver, spleen channel.Have and invigorate blood circulation, circulation of qi promoting, effect of pain relieving.
Herba Eupatorii: pungent, flat.Return spleen, stomach, lung meridian.Have removing dampness by means of aromatics, appetizing of being amusing, delivers effect of expelling summer-heat.
Massa Medicata Fermentata: sweet, acrid, warm.Return spleen, stomach warp.There is invigorating the spleen and regulating the stomach, effect of promoting digestion and removing stagnation.
Radix Gentianae: bitter in the mouth, cold in nature.Return lung, Liver Channel.There is heat clearing and damp drying, effect of eliminating pathogen in the liver gallbladder fire.
Herba Scutellariae Barbatae: acrid in the mouth, hardship, cold in nature.Return lung, liver, kidney channel.There is heat-clearing and toxic substances removing, effect of blood stasis dispelling diuresis.
Herba Pteridis Multifidae: bitter, cold.Return liver, stomach, lung, large intestine, urinary bladder channel.There is effect of anticancer, the removing damp-heat of relieving internal heat, cooling blood for hemostasis.
Fructus Setariae Germinatus: sweet, temperature.Return spleen, stomach warp.Have help digestion and in, effect of spleen benefiting and stimulating the appetite.
Radix Alangii: pungent, bitter, temperature.Return liver, kidney, heart channel.There is expelling wind and removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral, effect of scattered silt pain relieving.
Radix Ilicis Pubescentis: sweet, property is put down, nontoxic.Return lung, liver, large intestine channel.There is heat-clearing and toxic substances removing, effect of blood circulation and channel invigorating.
Herba Saxifragae: bitter, acrid, cold.There is heat-clearing and toxic substances removing, the effect of the removing heat from blood that dispels the wind.
Herba Cayatiae Japonicae: bitter, sour, cold.GUIXIN, liver, stomach three warp.There is clearing away heat-damp and promoting diuresis, effect of removing toxic substances and promoting subsidence of swelling.
Traditional medicine thinks that hepatitis B belongs to stagnation of liver-QI, hypochondriac pain, jaundice, pestilence, gathers category, and its cause of disease is got rid of evils in outward because positive QI-insufficiency is unable, causes the dark volt of epidemic disease poison and makes protracted inflammation not heal.Its pathogenesis is that the heresy of epidemic disease caused by damp-heat pathogen poison holds back volt taste, middle burnt stasis, production of fire due to stagnation of damp, cloudy liquid in consumer, and causes the hepatic and renal YIN deficiency; Its pathologic basis is the dirty imbalance of YIN and YANG of liver,spleen,kidney three, and pathogen stops up knot, damp and hot tired resistance qi depression to blood stasis.The medicine of the treatment hepatitis B that the present inventor sums up according to clinical experience and pharmaceutical research for many years, the all medicine reasonable compatibilities of this medicine, reach the effect regulating the dirty equilibrium between yin and yang of internal organs, heat-clearing and toxic substances removing, dispersing the stagnated live-QI to relieve the stagnation of QI, promoting blood circulation to remove blood stasis, replenishing QI to invigorate the spleen, promoting the function of the gallbladder to alleviate jaundice.Simultaneously Poria in pharmaceutical formulation of the present invention, Herba Artemisiae Scopariae also have effect of nourishing the liver, hepatoprotective, have significant effect to thoroughly curing hepatitis B.
The invention has the beneficial effects as follows: pharmaceutical formulation of the present invention is scientific and reasonable, each herbal medicine synergism that there is the effect regulating the dirty equilibrium between yin and yang of internal organs, heat-clearing and toxic substances removing, dispersing the stagnated live-QI to relieve the stagnation of QI, promoting blood circulation to remove blood stasis, replenishing QI to invigorate the spleen, promoting the function of the gallbladder to alleviate jaundice.Drug therapy cost of the present invention is low, be easy to absorption, instant effect, good effect, reach the object for the treatment of both the principal and secondary aspects of a disease, has no side effect, has good effect to treatment hepatitis B.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is described in further detail.
Embodiment 1
A kind of medicine for the treatment of hepatitis B, it is characterized in that, it is made up of the crude drug of following weight portion: Radix Sophorae Tonkinensis 20 parts, Herba Sedi 20 parts, 20 parts, Poria, Fructus Toosendan 10 parts, Rhizoma Imperatae 5 parts, Radix Angelicae Sinensis 10 parts, Herba Artemisiae Scopariae 20 parts, Herba Hedyotidis Diffusae 20 parts, Rhizoma Corydalis 10 parts, Herba Eupatorii 3 parts, Massa Medicata Fermentata 8 parts, Radix Gentianae 10 parts, Herba Scutellariae Barbatae 5 parts, Herba Pteridis Multifidae 6 parts, Fructus Setariae Germinatus 10 parts, Radix Alangii 3 parts, Radix Ilicis Pubescentis 10 parts, Herba Saxifragae 5 parts, Herba Cayatiae Japonicae 10 parts.
The preparation method of the present embodiment medicine is as follows:
(1) take above-mentioned formula ratio material medicine according to quantity, add 800-1000ml cold water soak wherein after 1 hour, first to burn to boiling slow fire boiling again 30 minutes with intense fire, filter to obtain 1 filtered juice;
(2) continuing to add water 500ml decoction to seething with excitement latter 25 minutes in filtering residue, filtering to obtain 2 filtered juices;
(3) 1,2 filtered juice is merged heating is concentrated into 400ml.
Embodiment 2
A kind of medicine for the treatment of hepatitis B, it is characterized in that, it is made up of the crude drug of following weight portion: Radix Sophorae Tonkinensis 30 parts, Herba Sedi 30 parts, 30 parts, Poria, Fructus Toosendan 20 parts, Rhizoma Imperatae 10 parts, Radix Angelicae Sinensis 20 parts, Herba Artemisiae Scopariae 30 parts, Herba Hedyotidis Diffusae 30 parts, Rhizoma Corydalis 20 parts, Herba Eupatorii 8 parts, Massa Medicata Fermentata 15 parts, Radix Gentianae 20 parts, Herba Scutellariae Barbatae 15 parts, Herba Pteridis Multifidae 12 parts, Fructus Setariae Germinatus 20 parts, Radix Alangii 9 parts, Radix Ilicis Pubescentis 20 parts, Herba Saxifragae 15 parts, Herba Cayatiae Japonicae 20 parts.
The preparation method of the present embodiment medicine is with embodiment 1.
Embodiment 3
A kind of medicine for the treatment of hepatitis B, it is characterized in that, it is made up of the crude drug of following weight portion: Radix Sophorae Tonkinensis 25 parts, Herba Sedi 25 parts, Poria 20-30 part, Fructus Toosendan 15 parts, Rhizoma Imperatae 8 parts, Radix Angelicae Sinensis 15 parts, Herba Artemisiae Scopariae 25 parts, Herba Hedyotidis Diffusae 25 parts, Rhizoma Corydalis 15 parts, Herba Eupatorii 6 parts, Massa Medicata Fermentata 12 parts, Radix Gentianae 15 parts, Herba Scutellariae Barbatae 10 parts, Herba Pteridis Multifidae 9 parts, Fructus Setariae Germinatus 15 parts, Radix Alangii 6 parts, Radix Ilicis Pubescentis 15 parts, Herba Saxifragae 10 parts, Herba Cayatiae Japonicae 15 parts.
The preparation method of the present embodiment medicine is with embodiment 1.
Embodiment 4
A kind of medicine for the treatment of hepatitis B, it is characterized in that, it is made up of the crude drug of following weight portion: Radix Sophorae Tonkinensis 28 parts, Herba Sedi 24 parts, 25 parts, Poria, Fructus Toosendan 18 parts, Rhizoma Imperatae 7 parts, Radix Angelicae Sinensis 15 parts, Herba Artemisiae Scopariae 22 parts, Herba Hedyotidis Diffusae 24 parts, Rhizoma Corydalis 12 parts, Herba Eupatorii 5 parts, Massa Medicata Fermentata 10 parts, Radix Gentianae 16 parts, Herba Scutellariae Barbatae 12 parts, Herba Pteridis Multifidae 10 parts, Fructus Setariae Germinatus 14 parts, Radix Alangii 5 parts, Radix Ilicis Pubescentis 14 parts, Herba Saxifragae 15 parts, Herba Cayatiae Japonicae 16 parts.
The preparation method of the present embodiment medicine is with embodiment 1.
Clinical practice example
1. clinical data: random selecting clinical hepatitis B patient 300 example, wherein acute hepatitis b 105 example, chronic viral hepatitis B 155 example, hbv-liver cirrhosis 40 example, the age 32-68 year.
2. diagnostic criteria:
Acute hepatitis b: occur without the explainable weak and symptom of digestive tract of other reasons, can have yellowish urine, eye Huang and Dermal icterus; Liver biochemistry inspection is abnormal, and mainly Serum ALT and AST raise, and serum bilirubin can be had to raise; HBsAg is positive; Tangible proof is had to show once to detect serum HBsAg feminine gender in 6 months; Anti-HBc IgM pg l:l more than 000; Liver histological meets acute viral hepatitis and changes; Convalescent serum HBsAg the moon turns, and Anti-HBsAg antibody sun turns.Meet above any one can make a definite diagnosis.
Chronic viral hepatitis B: still HBsAg was positive or find that the HBsAg positive was more than 6 months more than 6 months for acute HBV infection.HBsAg is positive, and the persistent period is not quite clear, and Anti-HBc Serum IgM is negative.The sign of patients with chronic liver as hepatic facies, liver palm, the pretty nevus regulating liver-QI of spider, splenomegaly etc.Serum ALT repeatedly or continue to raise, right plasma albumin reduces (or) globulin raises, or bilirubin rising etc.Liver pathology has the feature of graceful sexually transmitted disease (STD) virus hepatitis.The attached flight of steps leading to a palace hall of serum HBe Ag maybe can detect HBV DNA except other reasons causing ALT to raise.Can make a definite diagnosis for any 2 two or 3 above.
Hbv-liver cirrhosis: serum HBsAg is positive, or has clear and definite chronic viral hepatitis B medical history.Serum albumin reduces, or Serum ALT or AST raise, or serum bilirubin raises, with hypersplenism (platelet and (or) leukopenia), or clear and definite esophagus, varices of fundus of stomach, or hepatic encephalopathy or ascites.The imaging examinations such as abdominal part Type B is ultrasonic, CT or MRI have the typical performance of liver cirrhosis.Liver histological shows as diffuse fibrosis and pseudolobuli is formed.Meet above any 2 can make a definite diagnosis.
3. Therapeutic Method: use the embodiment of the present invention 3 gained medicine to carry out clinical treatment observation.Usage and consumption: decocting is oral, a side is potion, potion on the one, one day twice, sooner or later within 1 hour after meal, respectively takes 200ml.10 days 1 courses for the treatment of, general 3-5 can cure a course for the treatment of, and patient with severe symptoms 6-8 can cure a course for the treatment of.
4. curative effect determinate standard:
Cure: clinical symptoms, sign all disappear, liver function full recovery is normal, and B ultrasonic shows liver Non Apparent Abnormality, and routine blood test recovers normal, follows up a case by regular visits to more than 1 year without recurrence;
Effective: clinical symptoms, sign alleviate more than half or be clearly better, liver function part recovers normal;
Invalid: clinical symptoms, sign are all not improved.
5. therapeutic outcome: the results are shown in following table 1.
Case load Cure Effective Invalid Total effective rate %
Acute hepatitis b 105 65 39 1 99
Chronic viral hepatitis B 155 128 26 1 99.4
Hbv-liver cirrhosis 40 25 11 4 90
As can be seen from the above results, medicine of the present invention has good therapeutic effect to hepatitis B, it more than 99%, also reaches 90% to the total effective rate of hbv-liver cirrhosis to the treatment total effective rate of acute and chronic hepatitis B, because of but a kind of medicine for the treatment of hepatitis B well.

Claims (2)

1. treat the medicine of hepatitis B for one kind, it is characterized in that, it is made up of the crude drug of following weight portion: Radix Sophorae Tonkinensis 20-30 part, Herba Sedi 20-30 part, Poria 20-30 part, Fructus Toosendan 10-20 part, Rhizoma Imperatae 5-10 part, Radix Angelicae Sinensis 10-20 part, Herba Artemisiae Scopariae 20-30 part, Herba Hedyotidis Diffusae 20-30 part, Rhizoma Corydalis 10-20 part, Herba Eupatorii 3-8 part, Massa Medicata Fermentata 8-15 part, Radix Gentianae 10-20 part, Herba Scutellariae Barbatae 5-15 part, Herba Pteridis Multifidae 6-12 part, Fructus Setariae Germinatus 10-20 part, Radix Alangii 3-9 part, Radix Ilicis Pubescentis 10-20 part, Herba Saxifragae 5-15 part, Herba Cayatiae Japonicae 10-20 part.
2. the medicine for the treatment of hepatitis B according to claim 1, it is characterized in that, it is made up of the crude drug of following weight portion: Radix Sophorae Tonkinensis 25 parts, Herba Sedi 25 parts, Poria 20-30 part, Fructus Toosendan 15 parts, Rhizoma Imperatae 8 parts, Radix Angelicae Sinensis 15 parts, Herba Artemisiae Scopariae 25 parts, Herba Hedyotidis Diffusae 25 parts, Rhizoma Corydalis 15 parts, Herba Eupatorii 6 parts, Massa Medicata Fermentata 12 parts, Radix Gentianae 15 parts, Herba Scutellariae Barbatae 10 parts, Herba Pteridis Multifidae 9 parts, Fructus Setariae Germinatus 15 parts, Radix Alangii 6 parts, Radix Ilicis Pubescentis 15 parts, Herba Saxifragae 10 parts, Herba Cayatiae Japonicae 15 parts.
CN201510339730.9A 2015-06-18 2015-06-18 Medicine for treating hepatitis B Pending CN104888017A (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
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CN105311579A (en) * 2015-12-02 2016-02-10 陈晓黎 Traditional Chinese medicine composition for quickly treating hepatitis B

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Application publication date: 20150909