CN104857583A - Medical intracardiac pump device - Google Patents

Medical intracardiac pump device Download PDF

Info

Publication number
CN104857583A
CN104857583A CN201510190152.7A CN201510190152A CN104857583A CN 104857583 A CN104857583 A CN 104857583A CN 201510190152 A CN201510190152 A CN 201510190152A CN 104857583 A CN104857583 A CN 104857583A
Authority
CN
China
Prior art keywords
incubated
parts
hours
pump housing
ceramic material
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201510190152.7A
Other languages
Chinese (zh)
Inventor
傅风荣
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN201510190152.7A priority Critical patent/CN104857583A/en
Publication of CN104857583A publication Critical patent/CN104857583A/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/20—Type thereof
    • A61M60/205—Non-positive displacement blood pumps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/10—Location thereof with respect to the patient's body
    • A61M60/122—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
    • A61M60/126—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel
    • A61M60/148—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel in line with a blood vessel using resection or like techniques, e.g. permanent endovascular heart assist devices
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B35/00—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
    • C04B35/01—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on oxide ceramics
    • C04B35/46—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on oxide ceramics based on titanium oxides or titanates
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B35/00—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
    • C04B35/01—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on oxide ceramics
    • C04B35/48—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on oxide ceramics based on zirconium or hafnium oxides, zirconates, zircon or hafnates
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B35/00—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
    • C04B35/515—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on non-oxide ceramics
    • C04B35/56—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on non-oxide ceramics based on carbides or oxycarbides
    • C04B35/5607—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on non-oxide ceramics based on carbides or oxycarbides based on refractory metal carbides
    • C04B35/5611—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on non-oxide ceramics based on carbides or oxycarbides based on refractory metal carbides based on titanium carbides
    • C—CHEMISTRY; METALLURGY
    • C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
    • C22C—ALLOYS
    • C22C14/00—Alloys based on titanium

Landscapes

  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Ceramic Engineering (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Chemistry (AREA)
  • Materials Engineering (AREA)
  • Mechanical Engineering (AREA)
  • Manufacturing & Machinery (AREA)
  • Cardiology (AREA)
  • Structural Engineering (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Vascular Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Composite Materials (AREA)
  • Metallurgy (AREA)
  • Structures Of Non-Positive Displacement Pumps (AREA)

Abstract

The invention discloses a medical intracardiac pump device which comprises a pump body and an impeller mounted in the pump body, wherein the pump body comprises a cast titanium alloy pump body, a zirconia ceramic material layer on the outer surface of the pump body, and a titanium oxide ceramic material layer on the inner surface of the pump body; the impeller comprises a cast titanium alloy impeller body and a titanium carbide ceramic material layer on the outer surface of the cast titanium alloy impeller body. According to the situation that the pump body is in contact with different types of human body cells at different speeds, the inner surface and outer surface of the pump body are coated with the titanium oxide ceramic material layer and zirconia ceramic material layer respectively to improve the compatibility between the material and blood.

Description

A kind of medical intracardiac pump device
Technical field
The present invention relates to a kind of medical intracardiac pump device, belongs to implantable pump, belongs to technical field of medical instruments.
Background technology
Clinically, the patient for heart failure needs to treat by artificial mechanical's auxiliary device usually.Heart assistance therapy equipment main at present has blood pump.The existing blood pump in home and abroad mainly implantable auxiliary blood pump, confirmed blood pump is to the damage of blood constituent mainly haemolysis and thrombosis two kinds, and the former refers to erythrocytic breaking, and causes intracellular hemoglobin to dissociate in blood plasma; The latter refers to that platelet is assembled after being activated, and is deposited on blood contacting surface.Haemolysis and thrombosis all can cause the physiologic derangement of receptor, crisis life time serious.The existing pump housing and impeller material have been difficult to meet the performance requirement such as anti-hemolysis and antithrombotic.
Summary of the invention
The present invention is exactly that a kind of technique proposed for the problems referred to above is simple, cost is low, anti-hemolysis and the good medical intracardiac pump device of antithrombotic property.
A kind of medical intracardiac pump device, it impeller comprising a pump housing and be installed on pump body, the pump housing comprises: the zirconium oxide series ceramic material layer of the cast titanium alloy pump housing, pump housing outer surface and the titanium oxide base ceramic material layer of pump housing inner surface, impeller comprises the titanium carbide series ceramic material layer on cast titanium alloy impeller and cast titanium alloy impeller outer surface
It is characterized in that, cast titanium alloy pump housing chemical composition is (weight): Fe:10-12 ﹪, Al:8-9 ﹪, Si:5-6 ﹪, Zn:2-3 ﹪, Mg 1-2 ﹪, Y:0.3-0.4 ﹪, Cu:0.8-0.9 ﹪, Cd:0.2-0.3 ﹪, Zr:0.07-0.08 ﹪, V:0.06-0.07 ﹪, B:0.08-0.09 ﹪, surplus is Ti and inevitable impurity;
Cast titanium alloy pump housing preparation method: comprise the following steps: according to aforementioned proportion alloyage, alloy material melting, cast: smelting temperature: 1810-1820 DEG C, pouring temperature is 1750-1760 DEG C; After the demoulding, the pump housing obtained is heat-treated: first heated by the pump housing, is warming up to 900 DEG C, heating rate 300 DEG C/h, be incubated 5 hours, after be cooled to 600 DEG C, rate of temperature fall 100 DEG C/h, be incubated 7 hours, after be warming up to 750 DEG C, heating rate 100 DEG C/h, be incubated 3 hours, after be again cooled to 400 DEG C, rate of temperature fall 50 DEG C/h, be incubated 8 hours, after be again cooled to 200 DEG C, rate of temperature fall 40 DEG C/h, be incubated 5 hours, rear air cooling is to room temperature
Afterwards pickling and Passivation Treatment are carried out to pump housing surface, wherein:
Pickle consists of (weight): take 98% dense H 2sO 410-35 part, HCL 1-10 part of 36.5%, propanoic acid 5-10 part, ethylenediamine 1-5 part, alkyl imidazoline quaternary ammonium salt 10-15 part; Water 10-20 part;
Passivating solution consists of (weight): polyimides 1-3 part, 2-(3,4-epoxycyclohexyl) ethyl trimethoxy silane 4-10 part, N-(2-amino-ethyl)-3-amino propyl methyl dimethoxysilane 8-15 part, Sodium fluoroborate 10-13 part, sulphuric acid 1-4 part, dialkyl dithiophosphoric acid oxygen molybdenum 20-25 part, water 25-35 part;
Coated with zirconia series ceramic material is carried out to pump housing outer surface after passivation; Zirconium oxide series ceramic material layer is formed by being coated in pump housing outer surface, zirconium oxide series ceramic material layer thickness 0.4mm, zirconium oxide series ceramic material composition of layer comprises (weight): zirconium oxide 70-80 part, titanium boride 30-40 part, tungsten carbide 20-30 part, silicon oxide 1-2 part, the pump housing after coating is heated, be warming up to 800 DEG C, heating rate 250 DEG C/h, be incubated 5 hours, after be cooled to 600 DEG C, rate of temperature fall 100 DEG C/h, is incubated 4 hours, after be again cooled to 300 DEG C, rate of temperature fall 75 DEG C/h, be incubated 8 hours, rear air cooling is to room temperature
Afterwards coated with titanium oxide series ceramic material is carried out to pump housing inner surface, titanium oxide base ceramic material layer is formed by being coated in pump housing inner surface, titanium oxide base ceramic material layer thickness 0.5mm, titanium oxide base ceramic material composition of layer comprises (weight): titanium oxide 50-60 part, titanium nitride 20-30 part, chromium carbide 5-10 part, silicon oxide 1-2 part, the pump housing after coating is heated, be warming up to 700 DEG C, heating rate 200 DEG C/h, be incubated 3 hours, after be cooled to 500 DEG C, rate of temperature fall 100 DEG C/h, be incubated 7 hours, after be again cooled to 200 DEG C, rate of temperature fall 50 DEG C/h, be incubated 10 hours, rear air cooling is to room temperature, obtain the final pump housing,
Cast titanium alloy impeller chemical composition is (weight): Fe:10-15 ﹪, Al:10-13 ﹪, Si:5-10 ﹪, Zn:1-5 ﹪, La:0.5-0.8 ﹪, Cu:0.8-1 ﹪, Mg0.5-0.7 ﹪, Ag0.5-0.7 ﹪, Cd:0.3-0.5 ﹪, Zr:0.05-0.08 ﹪, V:0.01-0.02 ﹪, B:0.02-0.03 ﹪, surplus is Ti and inevitable impurity;
Cast titanium alloy impeller preparation method: comprise the following steps: according to aforementioned proportion alloyage, alloy material melting, cast: smelting temperature: 1810-1820 DEG C, pouring temperature is 1750-1760 DEG C; After the demoulding, the impeller obtained is heat-treated: first heated by impeller, is warming up to 900 DEG C, heating rate 300 DEG C/h, be incubated 5 hours, after be cooled to 600 DEG C, rate of temperature fall 100 DEG C/h, be incubated 7 hours, after be warming up to 750 DEG C, heating rate 100 DEG C/h, be incubated 3 hours, after be again cooled to 400 DEG C, rate of temperature fall 50 DEG C/h, be incubated 8 hours, after be again cooled to 200 DEG C, rate of temperature fall 40 DEG C/h, be incubated 5 hours, rear air cooling is to room temperature
Afterwards pickling and Passivation Treatment are carried out to impeller surface, wherein:
Pickle consists of (weight): take 98% dense H 2sO 410-35 part, HCL 1-10 part of 36.5%, propanoic acid 5-10 part, ethylenediamine 1-5 part, alkyl imidazoline quaternary ammonium salt 10-15 part; Water 10-20 part;
Passivating solution consists of (weight): polyimides 1-3 part, 2-(3,4-epoxycyclohexyl) ethyl trimethoxy silane 4-10 part, N-(2-amino-ethyl)-3-amino propyl methyl dimethoxysilane 8-15 part, Sodium fluoroborate 10-13 part, sulphuric acid 1-4 part, dialkyl dithiophosphoric acid oxygen molybdenum 20-25 part, water 25-35 part;
Shelling-out of titanium carbide series ceramic material is carried out to the impeller after passivation, titanium carbide series ceramic material layer is formed by being coated in impeller surface, titanium carbide series ceramic material layer thickness 0.4mm, titanium carbide series ceramic material composition of layer comprises (weight): titanium carbide 40-50 part, titanium nitride 10-15 part, chromium carbide 8 parts, silicon oxide 3-5 part, impeller after coating is heated, be warming up to 700 DEG C, heating rate 200 DEG C/h, be incubated 3 hours, after be cooled to 500 DEG C, rate of temperature fall 100 DEG C/h, be incubated 7 hours, after be again cooled to 200 DEG C, rate of temperature fall 50 DEG C/h, be incubated 10 hours, rear air cooling is to room temperature, obtain final impeller.
The medical intracardiac pump device of described one, cast titanium alloy pump housing chemical composition is: Fe:10 ﹪, Al:8 ﹪, Si:5 ﹪, Zn:2 ﹪, Mg 1 ﹪, Y:0.3 ﹪, Cu:0.8 ﹪, Cd:0.2 ﹪, Zr:0.07 ﹪, V:0.06 ﹪, B:0.08 ﹪, surplus is Ti and inevitable impurity.
The medical intracardiac pump device of described one, cast titanium alloy pump housing chemical composition is: Fe:12 ﹪, Al:9 ﹪, Si:6 ﹪, Zn:3 ﹪, Mg 2 ﹪, Y:0.4 ﹪, Cu:0.9 ﹪, Cd:0.3 ﹪, Zr:0.08 ﹪, V:0.07 ﹪, B:0.09 ﹪, surplus is Ti and inevitable impurity.
The medical intracardiac pump device of described one, cast titanium alloy pump housing chemical composition is: Fe:11 ﹪, Al:8.5 ﹪, Si:5.5 ﹪, Zn:2.5 ﹪, Mg 1.5 ﹪, Y:0.35 ﹪, Cu:0.85 ﹪, Cd:0.25 ﹪, Zr:0.075 ﹪, V:0.065 ﹪, B:0.085 ﹪, surplus is Ti and inevitable impurity.
The medical intracardiac pump device of described one, cast titanium alloy impeller chemical composition is (weight): Fe:10 ﹪, Al:10 ﹪, Si:5 ﹪, Zn:1 ﹪, La:0.5 ﹪, Cu:0.8 ﹪, Mg0.5 ﹪, Ag0.5 ﹪, Cd:0.3 ﹪, Zr:0.05 ﹪, V:0.01 ﹪, B:0.02 ﹪, surplus is Ti and inevitable impurity.
The medical intracardiac pump device of described one, cast titanium alloy impeller chemical composition is (weight): Fe:15 ﹪, Al:13 ﹪, Si:10 ﹪, Zn:5 ﹪, La:0.8 ﹪, Cu:1 ﹪, Mg0.7 ﹪, Ag0.7 ﹪, Cd:0.5 ﹪, Zr:0.08 ﹪, V:0.02 ﹪, B:0.03 ﹪, surplus is Ti and inevitable impurity.
The medical intracardiac pump device of described one, cast titanium alloy impeller chemical composition is (weight): Fe:13 ﹪, Al:11 ﹪, Si:7 ﹪, Zn:3 ﹪, La:0.6 ﹪, Cu:0.9 ﹪, Mg 0.6 ﹪, Ag 0.6 ﹪, Cd:0.4 ﹪, Zr:0.06 ﹪, V:0.015 ﹪, B:0.025 ﹪, surplus is Ti and inevitable impurity.
The medical intracardiac pump device of described one, zirconium oxide series ceramic material composition of layer comprises (weight): zirconium oxide 75 parts, titanium boride 35 parts, tungsten carbide 25 parts, silicon oxide 1.5 parts.
The medical intracardiac pump device of described one, titanium oxide base ceramic material composition of layer comprises (weight): titanium oxide 55 parts, titanium nitride 25 parts, chromium carbide 7 parts, silicon oxide 1.5 parts.
The medical intracardiac pump device of described one, titanium carbide series ceramic material composition of layer comprises (weight): titanium carbide 45 parts, titanium nitride 13 parts, chromium carbide 8 parts, silicon oxide 4 parts.
A kind of manufacture method of medical intracardiac pump device, it impeller comprising a pump housing and be installed on pump body, the pump housing comprises: the zirconium oxide series ceramic material layer of the cast titanium alloy pump housing, pump housing outer surface and the titanium oxide base ceramic material layer of pump housing inner surface, impeller comprises the titanium carbide series ceramic material layer on cast titanium alloy impeller and cast titanium alloy impeller outer surface
It is characterized in that, cast titanium alloy pump housing chemical composition is (weight): Fe:10-12 ﹪, Al:8-9 ﹪, Si:5-6 ﹪, Zn:2-3 ﹪, Mg 1-2 ﹪, Y:0.3-0.4 ﹪, Cu:0.8-0.9 ﹪, Cd:0.2-0.3 ﹪, Zr:0.07-0.08 ﹪, V:0.06-0.07 ﹪, B:0.08-0.09 ﹪, surplus is Ti and inevitable impurity;
Cast titanium alloy pump housing preparation method: comprise the following steps: according to aforementioned proportion alloyage, alloy material melting, cast: smelting temperature: 1810-1820 DEG C, pouring temperature is 1750-1760 DEG C; After the demoulding, the pump housing obtained is heat-treated: first heated by the pump housing, is warming up to 900 DEG C, heating rate 300 DEG C/h, be incubated 5 hours, after be cooled to 600 DEG C, rate of temperature fall 100 DEG C/h, be incubated 7 hours, after be warming up to 750 DEG C, heating rate 100 DEG C/h, be incubated 3 hours, after be again cooled to 400 DEG C, rate of temperature fall 50 DEG C/h, be incubated 8 hours, after be again cooled to 200 DEG C, rate of temperature fall 40 DEG C/h, be incubated 5 hours, rear air cooling is to room temperature
Afterwards pickling and Passivation Treatment are carried out to pump housing surface, wherein:
Pickle consists of (weight): take 98% dense H 2sO 410-35 part, HCL 1-10 part of 36.5%, propanoic acid 5-10 part, ethylenediamine 1-5 part, alkyl imidazoline quaternary ammonium salt 10-15 part; Water 10-20 part;
Passivating solution consists of (weight): polyimides 1-3 part, 2-(3,4-epoxycyclohexyl) ethyl trimethoxy silane 4-10 part, N-(2-amino-ethyl)-3-amino propyl methyl dimethoxysilane 8-15 part, Sodium fluoroborate 10-13 part, sulphuric acid 1-4 part, dialkyl dithiophosphoric acid oxygen molybdenum 20-25 part, water 25-35 part;
Coated with zirconia series ceramic material is carried out to pump housing outer surface after passivation; Zirconium oxide series ceramic material layer is formed by being coated in pump housing outer surface, zirconium oxide series ceramic material layer thickness 0.4mm, zirconium oxide series ceramic material composition of layer comprises (weight): zirconium oxide 70-80 part, titanium boride 30-40 part, tungsten carbide 20-30 part, silicon oxide 1-2 part, the pump housing after coating is heated, be warming up to 800 DEG C, heating rate 250 DEG C/h, be incubated 5 hours, after be cooled to 600 DEG C, rate of temperature fall 100 DEG C/h, is incubated 4 hours, after be again cooled to 300 DEG C, rate of temperature fall 75 DEG C/h, be incubated 8 hours, rear air cooling is to room temperature
Afterwards coated with titanium oxide series ceramic material is carried out to pump housing inner surface, titanium oxide base ceramic material layer is formed by being coated in pump housing inner surface, titanium oxide base ceramic material layer thickness 0.5mm, titanium oxide base ceramic material composition of layer comprises (weight): titanium oxide 50-60 part, titanium nitride 20-30 part, chromium carbide 5-10 part, silicon oxide 1-2 part, the pump housing after coating is heated, be warming up to 700 DEG C, heating rate 200 DEG C/h, be incubated 3 hours, after be cooled to 500 DEG C, rate of temperature fall 100 DEG C/h, be incubated 7 hours, after be again cooled to 200 DEG C, rate of temperature fall 50 DEG C/h, be incubated 10 hours, rear air cooling is to room temperature, obtain the final pump housing,
Cast titanium alloy impeller chemical composition is (weight): Fe:10-15 ﹪, Al:10-13 ﹪, Si:5-10 ﹪, Zn:1-5 ﹪, La:0.5-0.8 ﹪, Cu:0.8-1 ﹪, Mg0.5-0.7 ﹪, Ag0.5-0.7 ﹪, Cd:0.3-0.5 ﹪, Zr:0.05-0.08 ﹪, V:0.01-0.02 ﹪, B:0.02-0.03 ﹪, surplus is Ti and inevitable impurity;
Cast titanium alloy impeller preparation method: comprise the following steps: according to aforementioned proportion alloyage, alloy material melting, cast: smelting temperature: 1810-1820 DEG C, pouring temperature is 1750-1760 DEG C; After the demoulding, the impeller obtained is heat-treated: first heated by impeller, is warming up to 900 DEG C, heating rate 300 DEG C/h, be incubated 5 hours, after be cooled to 600 DEG C, rate of temperature fall 100 DEG C/h, be incubated 7 hours, after be warming up to 750 DEG C, heating rate 100 DEG C/h, be incubated 3 hours, after be again cooled to 400 DEG C, rate of temperature fall 50 DEG C/h, be incubated 8 hours, after be again cooled to 200 DEG C, rate of temperature fall 40 DEG C/h, be incubated 5 hours, rear air cooling is to room temperature
Afterwards pickling and Passivation Treatment are carried out to impeller surface, wherein:
Pickle consists of (weight): take 98% dense H 2sO 410-35 part, HCL 1-10 part of 36.5%, propanoic acid 5-10 part, ethylenediamine 1-5 part, alkyl imidazoline quaternary ammonium salt 10-15 part; Water 10-20 part;
Passivating solution consists of (weight): polyimides 1-3 part, 2-(3,4-epoxycyclohexyl) ethyl trimethoxy silane 4-10 part, N-(2-amino-ethyl)-3-amino propyl methyl dimethoxysilane 8-15 part, Sodium fluoroborate 10-13 part, sulphuric acid 1-4 part, dialkyl dithiophosphoric acid oxygen molybdenum 20-25 part, water 25-35 part;
Shelling-out of titanium carbide series ceramic material is carried out to the impeller after passivation, titanium carbide series ceramic material layer is formed by being coated in impeller surface, titanium carbide series ceramic material layer thickness 0.4mm, titanium carbide series ceramic material composition of layer comprises (weight): titanium carbide 40-50 part, titanium nitride 10-15 part, chromium carbide 8 parts, silicon oxide 3-5 part, impeller after coating is heated, be warming up to 700 DEG C, heating rate 200 DEG C/h, be incubated 3 hours, after be cooled to 500 DEG C, rate of temperature fall 100 DEG C/h, be incubated 7 hours, after be again cooled to 200 DEG C, rate of temperature fall 50 DEG C/h, be incubated 10 hours, rear air cooling is to room temperature, obtain final impeller.
Described pump housing inner surface can touch the part on pump body surface when to be blood inner by pump, pump housing remainder is pump housing outer surface.
Foregoing invention content is relative to the beneficial effect of prior art: 1) composition of titanium alloy is simple; 2) titanium alloy of this composition is carried out to the surface treatment procedure of pickling and passivation, avoid occurring the problems such as any surperficial stain, make acquisition surface clean and tidy; 3) by the inner surface of the pump housing that do not coexist according to the pump housing contact kind of human body cell and speed and outer surface titanium oxide base ceramic material and zirconium oxide series ceramic material layer, material and blood compatibility is improved.5) by the surface-coated titanium carbide series ceramic material of the pump housing that do not coexist in the kind and speed that contact human body cell according to impeller, anti-hemolysis and antithrombotic property is improved.
Detailed description of the invention
In order to there be understanding clearly to technical characteristic of the present invention, object and effect, now describe the specific embodiment of the present invention in detail.
Embodiment 1
A kind of medical intracardiac pump device, it impeller comprising a pump housing and be installed on pump body, the pump housing comprises: the zirconium oxide series ceramic material layer of the cast titanium alloy pump housing, pump housing outer surface and the titanium oxide base ceramic material layer of pump housing inner surface, impeller comprises the titanium carbide series ceramic material layer on cast titanium alloy impeller and cast titanium alloy impeller outer surface
It is characterized in that, cast titanium alloy pump housing chemical composition is (weight): Fe:10 ﹪, Al:8 ﹪, Si:5 ﹪, Zn:2 ﹪, Mg 1 ﹪, Y:0.3 ﹪, Cu:0.8 ﹪, Cd:0.2 ﹪, Zr:0.07 ﹪, V:0.06 ﹪, B:0.08 ﹪, surplus is Ti and inevitable impurity;
Cast titanium alloy pump housing preparation method: comprise the following steps: according to aforementioned proportion alloyage, alloy material melting, cast: smelting temperature: 1810 DEG C, pouring temperature is 1750 DEG C; After the demoulding, the pump housing obtained is heat-treated: first heated by the pump housing, is warming up to 900 DEG C, heating rate 300 DEG C/h, be incubated 5 hours, after be cooled to 600 DEG C, rate of temperature fall 100 DEG C/h, be incubated 7 hours, after be warming up to 750 DEG C, heating rate 100 DEG C/h, be incubated 3 hours, after be again cooled to 400 DEG C, rate of temperature fall 50 DEG C/h, be incubated 8 hours, after be again cooled to 200 DEG C, rate of temperature fall 40 DEG C/h, be incubated 5 hours, rear air cooling is to room temperature
Afterwards pickling and Passivation Treatment are carried out to pump housing surface, wherein:
Pickle consists of (weight): take 98% dense H 2sO 410 parts, the HCL of 36.5% 1 part, propanoic acid 5 parts, ethylenediamine 1 part, alkyl imidazoline quaternary ammonium salt 10 parts; 10 parts, water;
Passivating solution consists of (weight): polyimides 1 part, 2-(3,4-epoxycyclohexyl) ethyl trimethoxy silane 4 parts, N-(2-amino-ethyl)-3-amino propyl methyl dimethoxysilane 8 parts, Sodium fluoroborate 10 parts, 1 part, sulphuric acid, dialkyl dithiophosphoric acid oxygen molybdenum 20 parts, 25 parts, water;
Coated with zirconia series ceramic material is carried out to pump housing outer surface after passivation; Zirconium oxide series ceramic material layer is formed by being coated in pump housing outer surface, zirconium oxide series ceramic material layer thickness 0.4mm, zirconium oxide series ceramic material composition of layer comprises (weight): zirconium oxide 70 parts, titanium boride 30 parts, tungsten carbide 20 parts, silicon oxide 1 part, the pump housing after coating is heated, be warming up to 800 DEG C, heating rate 250 DEG C/h, be incubated 5 hours, after be cooled to 600 DEG C, rate of temperature fall 100 DEG C/h, is incubated 4 hours, after be again cooled to 300 DEG C, rate of temperature fall 75 DEG C/h, be incubated 8 hours, rear air cooling is to room temperature
Afterwards coated with titanium oxide series ceramic material is carried out to pump housing inner surface, titanium oxide base ceramic material layer is formed by being coated in pump housing inner surface, titanium oxide base ceramic material layer thickness 0.5mm, titanium oxide base ceramic material composition of layer comprises (weight): titanium oxide 50 parts, titanium nitride 20 parts, chromium carbide 5 parts, silicon oxide 1 part, the pump housing after coating is heated, be warming up to 700 DEG C, heating rate 200 DEG C/h, be incubated 3 hours, after be cooled to 500 DEG C, rate of temperature fall 100 DEG C/h, be incubated 7 hours, after be again cooled to 200 DEG C, rate of temperature fall 50 DEG C/h, be incubated 10 hours, rear air cooling is to room temperature, obtain the final pump housing,
Cast titanium alloy impeller chemical composition is (weight): Fe:10 ﹪, Al:10 ﹪, Si:5 ﹪, Zn:1 ﹪, La:0.5 ﹪, Cu:0.8 ﹪, Mg0.5 ﹪, Ag0.5 ﹪, Cd:0.3 ﹪, Zr:0.05 ﹪, V:0.01 ﹪, B:0.02 ﹪, surplus is Ti and inevitable impurity;
Cast titanium alloy impeller preparation method: comprise the following steps: according to aforementioned proportion alloyage, alloy material melting, cast: smelting temperature: 1810 DEG C, pouring temperature is 1750 DEG C; After the demoulding, the impeller obtained is heat-treated: first heated by impeller, is warming up to 900 DEG C, heating rate 300 DEG C/h, be incubated 5 hours, after be cooled to 600 DEG C, rate of temperature fall 100 DEG C/h, be incubated 7 hours, after be warming up to 750 DEG C, heating rate 100 DEG C/h, be incubated 3 hours, after be again cooled to 400 DEG C, rate of temperature fall 50 DEG C/h, be incubated 8 hours, after be again cooled to 200 DEG C, rate of temperature fall 40 DEG C/h, be incubated 5 hours, rear air cooling is to room temperature
Afterwards pickling and Passivation Treatment are carried out to impeller surface, wherein:
Pickle consists of (weight): take 98% dense H 2sO 410 parts, the HCL of 36.5% 1 part, propanoic acid 5 parts, ethylenediamine 1 part, alkyl imidazoline quaternary ammonium salt 10 parts; 10 parts, water;
Passivating solution consists of (weight): polyimides 1 part, 2-(3,4-epoxycyclohexyl) ethyl trimethoxy silane 4 parts, N-(2-amino-ethyl)-3-amino propyl methyl dimethoxysilane 8 parts, Sodium fluoroborate 10 parts, 1 part, sulphuric acid, dialkyl dithiophosphoric acid oxygen molybdenum 20 parts, 25 parts, water;
Shelling-out of titanium carbide series ceramic material is carried out to the impeller after passivation; Titanium carbide series ceramic material layer is formed by being coated in impeller surface, titanium carbide series ceramic material layer thickness 0.4mm, titanium carbide series ceramic material composition of layer comprises (weight): titanium carbide 40 parts, titanium nitride 10 parts, chromium carbide 8 parts, silicon oxide 3 parts, impeller after coating is heated, be warming up to 700 DEG C, heating rate 200 DEG C/h, be incubated 3 hours, after be cooled to 500 DEG C, rate of temperature fall 100 DEG C/h, is incubated 7 hours, after be again cooled to 200 DEG C, rate of temperature fall 50 DEG C/h, be incubated 10 hours, rear air cooling, to room temperature, obtains final impeller.
Embodiment 2
A kind of medical intracardiac pump device, it impeller comprising a pump housing and be installed on pump body, the pump housing comprises: the zirconium oxide series ceramic material layer of the cast titanium alloy pump housing, pump housing outer surface and the titanium oxide base ceramic material layer of pump housing inner surface, impeller comprises the titanium carbide series ceramic material layer on cast titanium alloy impeller and cast titanium alloy impeller outer surface
It is characterized in that, cast titanium alloy pump housing chemical composition is (weight): Fe:12 ﹪, Al:9 ﹪, Si:6 ﹪, Zn:3 ﹪, Mg 2 ﹪, Y:0.4 ﹪, Cu:0.9 ﹪, Cd:0.3 ﹪, Zr:0.08 ﹪, V:0.07 ﹪, B:0.09 ﹪, surplus is Ti and inevitable impurity;
Cast titanium alloy pump housing preparation method: comprise the following steps: according to aforementioned proportion alloyage, alloy material melting, cast: smelting temperature: 1820 DEG C, pouring temperature is 1760 DEG C; After the demoulding, the pump housing obtained is heat-treated: first heated by the pump housing, is warming up to 900 DEG C, heating rate 300 DEG C/h, be incubated 5 hours, after be cooled to 600 DEG C, rate of temperature fall 100 DEG C/h, be incubated 7 hours, after be warming up to 750 DEG C, heating rate 100 DEG C/h, be incubated 3 hours, after be again cooled to 400 DEG C, rate of temperature fall 50 DEG C/h, be incubated 8 hours, after be again cooled to 200 DEG C, rate of temperature fall 40 DEG C/h, be incubated 5 hours, rear air cooling is to room temperature
Afterwards pickling and Passivation Treatment are carried out to pump housing surface, wherein:
Pickle consists of (weight): take 98% dense H 2sO 435 parts, the HCL of 36.5% 10 parts, propanoic acid 10 parts, ethylenediamine 5 parts, alkyl imidazoline quaternary ammonium salt 15 parts; 20 parts, water;
Passivating solution consists of (weight): polyimides 3 parts, 2-(3,4-epoxycyclohexyl) ethyl trimethoxy silane 10 parts, N-(2-amino-ethyl)-3-amino propyl methyl dimethoxysilane 15 parts, Sodium fluoroborate 13 parts, 4 parts, sulphuric acid, dialkyl dithiophosphoric acid oxygen molybdenum 25 parts, 35 parts, water;
Coated with zirconia series ceramic material is carried out to pump housing outer surface after passivation; Zirconium oxide series ceramic material layer is formed by being coated in pump housing outer surface, zirconium oxide series ceramic material layer thickness 0.4mm, zirconium oxide series ceramic material composition of layer comprises (weight): zirconium oxide 80 parts, titanium boride 40 parts, tungsten carbide 30 parts, silicon oxide 2 parts, the pump housing after coating is heated, be warming up to 800 DEG C, heating rate 250 DEG C/h, be incubated 5 hours, after be cooled to 600 DEG C, rate of temperature fall 100 DEG C/h, is incubated 4 hours, after be again cooled to 300 DEG C, rate of temperature fall 75 DEG C/h, be incubated 8 hours, rear air cooling is to room temperature
Afterwards coated with titanium oxide series ceramic material is carried out to pump housing inner surface, titanium oxide base ceramic material layer is formed by being coated in pump housing inner surface, titanium oxide base ceramic material layer thickness 0.5mm, titanium oxide base ceramic material composition of layer comprises (weight): titanium oxide 60 parts, titanium nitride 30 parts, chromium carbide 10 parts, silicon oxide 2 parts, the pump housing after coating is heated, be warming up to 700 DEG C, heating rate 200 DEG C/h, be incubated 3 hours, after be cooled to 500 DEG C, rate of temperature fall 100 DEG C/h, be incubated 7 hours, after be again cooled to 200 DEG C, rate of temperature fall 50 DEG C/h, be incubated 10 hours, rear air cooling is to room temperature, obtain the final pump housing,
Cast titanium alloy impeller chemical composition is (weight): Fe:15 ﹪, Al:13 ﹪, Si:10 ﹪, Zn:5 ﹪, La:0.8 ﹪, Cu:1 ﹪, Mg0.7 ﹪, Ag0.7 ﹪, Cd:0.5 ﹪, Zr:0.08 ﹪, V:0.02 ﹪, B:0.03 ﹪, surplus is Ti and inevitable impurity;
Cast titanium alloy impeller preparation method: comprise the following steps: according to aforementioned proportion alloyage, alloy material melting, cast: smelting temperature: 1820 DEG C, pouring temperature is 1760 DEG C; After the demoulding, the impeller obtained is heat-treated: first heated by impeller, is warming up to 900 DEG C, heating rate 300 DEG C/h, be incubated 5 hours, after be cooled to 600 DEG C, rate of temperature fall 100 DEG C/h, be incubated 7 hours, after be warming up to 750 DEG C, heating rate 100 DEG C/h, be incubated 3 hours, after be again cooled to 400 DEG C, rate of temperature fall 50 DEG C/h, be incubated 8 hours, after be again cooled to 200 DEG C, rate of temperature fall 40 DEG C/h, be incubated 5 hours, rear air cooling is to room temperature
Afterwards pickling and Passivation Treatment are carried out to impeller surface, wherein:
Pickle consists of (weight): take 98% dense H 2sO 435 parts, the HCL of 36.5% 10 parts, propanoic acid 10 parts, ethylenediamine 5 parts, alkyl imidazoline quaternary ammonium salt 15 parts; 20 parts, water;
Passivating solution consists of (weight): polyimides 3 parts, 2-(3,4-epoxycyclohexyl) ethyl trimethoxy silane 10 parts, N-(2-amino-ethyl)-3-amino propyl methyl dimethoxysilane 15 parts, Sodium fluoroborate 13 parts, 4 parts, sulphuric acid, dialkyl dithiophosphoric acid oxygen molybdenum 25 parts, 35 parts, water;
Shelling-out of titanium carbide series ceramic material is carried out to the impeller after passivation; Titanium carbide series ceramic material layer is formed by being coated in impeller surface, titanium carbide series ceramic material layer thickness 0.4mm, titanium carbide series ceramic material composition of layer comprises (weight): titanium carbide 50 parts, titanium nitride 15 parts, chromium carbide 8 parts, silicon oxide 5 parts, impeller after coating is heated, be warming up to 700 DEG C, heating rate 200 DEG C/h, be incubated 3 hours, after be cooled to 500 DEG C, rate of temperature fall 100 DEG C/h, is incubated 7 hours, after be again cooled to 200 DEG C, rate of temperature fall 50 DEG C/h, be incubated 10 hours, rear air cooling, to room temperature, obtains final impeller.
Embodiment 3
A kind of medical intracardiac pump device, it impeller comprising a pump housing and be installed on pump body, the pump housing comprises: the zirconium oxide series ceramic material layer of the cast titanium alloy pump housing, pump housing outer surface and the titanium oxide base ceramic material layer of pump housing inner surface, impeller comprises the titanium carbide series ceramic material layer on cast titanium alloy impeller and cast titanium alloy impeller outer surface
It is characterized in that, cast titanium alloy pump housing chemical composition is (weight): Fe:11 ﹪, Al:8.5 ﹪, Si:5.5 ﹪, Zn:2.5 ﹪, Mg 1.5 ﹪, Y:0.35 ﹪, Cu:0.85 ﹪, Cd:0.25 ﹪, Zr:0.075 ﹪, V:0.065 ﹪, B:0.085 ﹪, surplus is Ti and inevitable impurity;
Cast titanium alloy pump housing preparation method: comprise the following steps: according to aforementioned proportion alloyage, alloy material melting, cast: smelting temperature: 1815 DEG C, pouring temperature is 1755 DEG C; After the demoulding, the pump housing obtained is heat-treated: first heated by the pump housing, is warming up to 900 DEG C, heating rate 300 DEG C/h, be incubated 5 hours, after be cooled to 600 DEG C, rate of temperature fall 100 DEG C/h, be incubated 7 hours, after be warming up to 750 DEG C, heating rate 100 DEG C/h, be incubated 3 hours, after be again cooled to 400 DEG C, rate of temperature fall 50 DEG C/h, be incubated 8 hours, after be again cooled to 200 DEG C, rate of temperature fall 40 DEG C/h, be incubated 5 hours, rear air cooling is to room temperature
Afterwards pickling and Passivation Treatment are carried out to pump housing surface, wherein:
Pickle consists of (weight): take 98% dense H 2sO 420 parts, the HCL of 36.5% 5 parts, propanoic acid 7 parts, ethylenediamine 3 parts, alkyl imidazoline quaternary ammonium salt 13 parts; 15 parts, water;
Passivating solution consists of (weight): polyimides 2 parts, 2-(3,4-epoxycyclohexyl) ethyl trimethoxy silane 7 parts, N-(2-amino-ethyl)-3-amino propyl methyl dimethoxysilane 12 parts, Sodium fluoroborate 11 parts, 2 parts, sulphuric acid, dialkyl dithiophosphoric acid oxygen molybdenum 23 parts, 30 parts, water;
Coated with zirconia series ceramic material is carried out to pump housing outer surface after passivation; Zirconium oxide series ceramic material layer is formed by being coated in pump housing outer surface, zirconium oxide series ceramic material layer thickness 0.4mm, zirconium oxide series ceramic material composition of layer comprises (weight): zirconium oxide 75 parts, titanium boride 35 parts, tungsten carbide 25 parts, silicon oxide 1.5 parts, the pump housing after coating is heated, be warming up to 800 DEG C, heating rate 250 DEG C/h, be incubated 5 hours, after be cooled to 600 DEG C, rate of temperature fall 100 DEG C/h, is incubated 4 hours, after be again cooled to 300 DEG C, rate of temperature fall 75 DEG C/h, be incubated 8 hours, rear air cooling is to room temperature
Afterwards coated with titanium oxide series ceramic material is carried out to pump housing inner surface, titanium oxide base ceramic material layer is formed by being coated in pump housing inner surface, titanium oxide base ceramic material layer thickness 0.5mm, titanium oxide base ceramic material composition of layer comprises (weight): titanium oxide 55 parts, titanium nitride 25 parts, chromium carbide 7 parts, silicon oxide 1.5 parts, the pump housing after coating is heated, be warming up to 700 DEG C, heating rate 200 DEG C/h, be incubated 3 hours, after be cooled to 500 DEG C, rate of temperature fall 100 DEG C/h, be incubated 7 hours, after be again cooled to 200 DEG C, rate of temperature fall 50 DEG C/h, be incubated 10 hours, rear air cooling is to room temperature, obtain the final pump housing,
Cast titanium alloy impeller chemical composition is (weight): Fe:13 ﹪, Al:12 ﹪, Si:7 ﹪, Zn:3 ﹪, La:0.6 ﹪, Cu:0.9 ﹪, Mg0.6 ﹪, Ag0.6 ﹪, Cd:0.4 ﹪, Zr:0.06 ﹪, V:0.015 ﹪, B:0.025 ﹪, surplus is Ti and inevitable impurity;
Cast titanium alloy impeller preparation method: comprise the following steps: according to aforementioned proportion alloyage, alloy material melting, cast: smelting temperature: 1815 DEG C, pouring temperature is 1755 DEG C; After the demoulding, the impeller obtained is heat-treated: first heated by impeller, is warming up to 900 DEG C, heating rate 300 DEG C/h, be incubated 5 hours, after be cooled to 600 DEG C, rate of temperature fall 100 DEG C/h, be incubated 7 hours, after be warming up to 750 DEG C, heating rate 100 DEG C/h, be incubated 3 hours, after be again cooled to 400 DEG C, rate of temperature fall 50 DEG C/h, be incubated 8 hours, after be again cooled to 200 DEG C, rate of temperature fall 40 DEG C/h, be incubated 5 hours, rear air cooling is to room temperature
Afterwards pickling and Passivation Treatment are carried out to impeller surface, wherein:
Pickle consists of (weight): take 98% dense H 2sO 420 parts, the HCL of 36.5% 5 parts, propanoic acid 7 parts, ethylenediamine 3 parts, alkyl imidazoline quaternary ammonium salt 13 parts; 15 parts, water;
Passivating solution consists of (weight): polyimides 2 parts, 2-(3,4-epoxycyclohexyl) ethyl trimethoxy silane 7 parts, N-(2-amino-ethyl)-3-amino propyl methyl dimethoxysilane 12 parts, Sodium fluoroborate 11 parts, 3 parts, sulphuric acid, dialkyl dithiophosphoric acid oxygen molybdenum 23 parts, 30 parts, water;
Shelling-out of titanium carbide series ceramic material is carried out to the impeller after passivation; Titanium carbide series ceramic material layer is formed by being coated in impeller surface, titanium carbide series ceramic material layer thickness 0.4mm, titanium carbide series ceramic material composition of layer comprises (weight): titanium carbide 45 parts, titanium nitride 13 parts, chromium carbide 8 parts, silicon oxide 4 parts, impeller after coating is heated, be warming up to 700 DEG C, heating rate 200 DEG C/h, be incubated 3 hours, after be cooled to 500 DEG C, rate of temperature fall 100 DEG C/h, is incubated 7 hours, after be again cooled to 200 DEG C, rate of temperature fall 50 DEG C/h, be incubated 10 hours, rear air cooling, to room temperature, obtains final impeller.
Embodiment 4
A kind of medical intracardiac pump device, it impeller comprising a pump housing and be installed on pump body, the pump housing comprises: the zirconium oxide series ceramic material layer of the cast titanium alloy pump housing, pump housing outer surface and the titanium oxide base ceramic material layer of pump housing inner surface, impeller comprises the titanium carbide series ceramic material layer on cast titanium alloy impeller and cast titanium alloy impeller outer surface
It is characterized in that, cast titanium alloy pump housing chemical composition is (weight): Fe:10.2 ﹪, Al:8.4 ﹪, Si:5.1 ﹪, Zn:2.3 ﹪, Mg 1.3 ﹪, Y:0.34 ﹪, Cu:0.83 ﹪, Cd:0.22 ﹪, Zr:0.071 ﹪, V:0.061 ﹪, B:0.083 ﹪, surplus is Ti and inevitable impurity;
Cast titanium alloy pump housing preparation method: comprise the following steps: according to aforementioned proportion alloyage, alloy material melting, cast: smelting temperature: 1814 DEG C, pouring temperature is 1752 DEG C; After the demoulding, the pump housing obtained is heat-treated: first heated by the pump housing, is warming up to 900 DEG C, heating rate 300 DEG C/h, be incubated 5 hours, after be cooled to 600 DEG C, rate of temperature fall 100 DEG C/h, be incubated 7 hours, after be warming up to 750 DEG C, heating rate 100 DEG C/h, be incubated 3 hours, after be again cooled to 400 DEG C, rate of temperature fall 50 DEG C/h, be incubated 8 hours, after be again cooled to 200 DEG C, rate of temperature fall 40 DEG C/h, be incubated 5 hours, rear air cooling is to room temperature
Afterwards pickling and Passivation Treatment are carried out to pump housing surface, wherein:
Pickle consists of (weight): take 98% dense H 2sO 412 parts, the HCL of 36.5% 2 parts, propanoic acid 6 parts, ethylenediamine 2 parts, alkyl imidazoline quaternary ammonium salt 11 parts; 11 parts, water;
Passivating solution consists of (weight): polyimides 1.3 parts, 2-(3,4-epoxycyclohexyl) ethyl trimethoxy silane 5 parts, N-(2-amino-ethyl)-3-amino propyl methyl dimethoxysilane 9 parts, Sodium fluoroborate 10.4 parts, 2 parts, sulphuric acid, dialkyl dithiophosphoric acid oxygen molybdenum 21 parts, 26 parts, water;
Coated with zirconia series ceramic material is carried out to pump housing outer surface after passivation; Zirconium oxide series ceramic material layer is formed by being coated in pump housing outer surface, zirconium oxide series ceramic material layer thickness 0.4mm, zirconium oxide series ceramic material composition of layer comprises (weight): zirconium oxide 71 parts, titanium boride 32 parts, tungsten carbide 22 parts, silicon oxide 1.2 parts, the pump housing after coating is heated, be warming up to 800 DEG C, heating rate 250 DEG C/h, be incubated 5 hours, after be cooled to 600 DEG C, rate of temperature fall 100 DEG C/h, is incubated 4 hours, after be again cooled to 300 DEG C, rate of temperature fall 75 DEG C/h, be incubated 8 hours, rear air cooling is to room temperature
Afterwards coated with titanium oxide series ceramic material is carried out to pump housing inner surface, titanium oxide base ceramic material layer is formed by being coated in pump housing inner surface, titanium oxide base ceramic material layer thickness 0.5mm, titanium oxide base ceramic material composition of layer comprises (weight): titanium oxide 51 parts, titanium nitride 22 parts, chromium carbide 6 parts, silicon oxide 1.4 parts, the pump housing after coating is heated, be warming up to 700 DEG C, heating rate 200 DEG C/h, be incubated 3 hours, after be cooled to 500 DEG C, rate of temperature fall 100 DEG C/h, be incubated 7 hours, after be again cooled to 200 DEG C, rate of temperature fall 50 DEG C/h, be incubated 10 hours, rear air cooling is to room temperature, obtain the final pump housing,
Cast titanium alloy impeller chemical composition is (weight): Fe:11 ﹪, Al:11 ﹪, Si:6 ﹪, Zn:2 ﹪, La:0.6 ﹪, Cu:0.82 ﹪, Mg0.53 ﹪, Ag0.4 ﹪, Cd:0.33 ﹪, Zr:0.052 ﹪, V:0.011 ﹪, B:0.021 ﹪, surplus is Ti and inevitable impurity;
Cast titanium alloy impeller preparation method: comprise the following steps: according to aforementioned proportion alloyage, alloy material melting, cast: smelting temperature: 1811 DEG C, pouring temperature is 1752 DEG C; After the demoulding, the impeller obtained is heat-treated: first heated by impeller, is warming up to 900 DEG C, heating rate 300 DEG C/h, be incubated 5 hours, after be cooled to 600 DEG C, rate of temperature fall 100 DEG C/h, be incubated 7 hours, after be warming up to 750 DEG C, heating rate 100 DEG C/h, be incubated 3 hours, after be again cooled to 400 DEG C, rate of temperature fall 50 DEG C/h, be incubated 8 hours, after be again cooled to 200 DEG C, rate of temperature fall 40 DEG C/h, be incubated 5 hours, rear air cooling is to room temperature
Afterwards pickling and Passivation Treatment are carried out to impeller surface, wherein:
Pickle consists of (weight): take 98% dense H 2sO 413 parts, the HCL of 36.5% 2 parts, propanoic acid 6 parts, ethylenediamine 2 parts, alkyl imidazoline quaternary ammonium salt 11 parts; 11 parts, water;
Passivating solution consists of (weight): polyimides 1.1 parts, 2-(3,4-epoxycyclohexyl) ethyl trimethoxy silane 5 parts, N-(2-amino-ethyl)-3-amino propyl methyl dimethoxysilane 9 parts, Sodium fluoroborate 10.3 parts, 1.1 parts, sulphuric acid, dialkyl dithiophosphoric acid oxygen molybdenum 21 parts, 26 parts, water;
Shelling-out of titanium carbide series ceramic material is carried out to the impeller after passivation, titanium carbide series ceramic material layer is formed by being coated in impeller surface, titanium carbide series ceramic material layer thickness 0.4mm, titanium carbide series ceramic material composition of layer comprises (weight): titanium carbide 41 parts, titanium nitride 11 parts, chromium carbide 8 parts, silicon oxide 3.2 parts, impeller after coating is heated, be warming up to 700 DEG C, heating rate 200 DEG C/h, be incubated 3 hours, after be cooled to 500 DEG C, rate of temperature fall 100 DEG C/h, be incubated 7 hours, after be again cooled to 200 DEG C, rate of temperature fall 50 DEG C/h, be incubated 10 hours, rear air cooling is to room temperature, obtain final impeller.
Embodiment 5
A kind of medical intracardiac pump device, it impeller comprising a pump housing and be installed on pump body, the pump housing comprises: the zirconium oxide series ceramic material layer of the cast titanium alloy pump housing, pump housing outer surface and the titanium oxide base ceramic material layer of pump housing inner surface, impeller comprises the titanium carbide series ceramic material layer on cast titanium alloy impeller and cast titanium alloy impeller outer surface
It is characterized in that, cast titanium alloy pump housing chemical composition is (weight): Fe:11.7 ﹪, Al:8.8 ﹪, Si:5.9 ﹪, Zn:2.6 ﹪, Mg 1.7 ﹪, Y:0.36 ﹪, Cu:0.87 ﹪, Cd:0.28 ﹪, Zr:0.079 ﹪, V:0.066 ﹪, B:0.089 ﹪, surplus is Ti and inevitable impurity;
Cast titanium alloy pump housing preparation method: comprise the following steps: according to aforementioned proportion alloyage, alloy material melting, cast: smelting temperature: 1816 DEG C, pouring temperature is 1757 DEG C; After the demoulding, the pump housing obtained is heat-treated: first heated by the pump housing, is warming up to 900 DEG C, heating rate 300 DEG C/h, be incubated 5 hours, after be cooled to 600 DEG C, rate of temperature fall 100 DEG C/h, be incubated 7 hours, after be warming up to 750 DEG C, heating rate 100 DEG C/h, be incubated 3 hours, after be again cooled to 400 DEG C, rate of temperature fall 50 DEG C/h, be incubated 8 hours, after be again cooled to 200 DEG C, rate of temperature fall 40 DEG C/h, be incubated 5 hours, rear air cooling is to room temperature
Afterwards pickling and Passivation Treatment are carried out to pump housing surface, wherein:
Pickle consists of (weight): take 98% dense H 2sO 433 parts, the HCL of 36.5% 9 parts, propanoic acid 9 parts, ethylenediamine 4 parts, alkyl imidazoline quaternary ammonium salt 14 parts; 19 parts, water;
Passivating solution consists of (weight): polyimides 2.8 parts, 2-(3,4-epoxycyclohexyl) ethyl trimethoxy silane 9 parts, N-(2-amino-ethyl)-3-amino propyl methyl dimethoxysilane 14 parts, Sodium fluoroborate 12.8 parts, 3.8 parts, sulphuric acid, dialkyl dithiophosphoric acid oxygen molybdenum 24 parts, 33 parts, water;
Coated with zirconia series ceramic material is carried out to pump housing outer surface after passivation; Zirconium oxide series ceramic material layer is formed by being coated in pump housing outer surface, zirconium oxide series ceramic material layer thickness 0.4mm, zirconium oxide series ceramic material composition of layer comprises (weight): zirconium oxide 77 parts, titanium boride 38 parts, tungsten carbide 29 parts, silicon oxide 1.8 parts, the pump housing after coating is heated, be warming up to 800 DEG C, heating rate 250 DEG C/h, be incubated 5 hours, after be cooled to 600 DEG C, rate of temperature fall 100 DEG C/h, is incubated 4 hours, after be again cooled to 300 DEG C, rate of temperature fall 75 DEG C/h, be incubated 8 hours, rear air cooling is to room temperature
Afterwards coated with titanium oxide series ceramic material is carried out to pump housing inner surface, titanium oxide base ceramic material layer is formed by being coated in pump housing inner surface, titanium oxide base ceramic material layer thickness 0.5mm, titanium oxide base ceramic material composition of layer comprises (weight): titanium oxide 58 parts, titanium nitride 27 parts, chromium carbide 9 parts, silicon oxide 1.7 parts, the pump housing after coating is heated, be warming up to 700 DEG C, heating rate 200 DEG C/h, be incubated 3 hours, after be cooled to 500 DEG C, rate of temperature fall 100 DEG C/h, be incubated 7 hours, after be again cooled to 200 DEG C, rate of temperature fall 50 DEG C/h, be incubated 10 hours, rear air cooling is to room temperature, obtain the final pump housing,
Cast titanium alloy impeller chemical composition is (weight): Fe:14 ﹪, Al:12.7 ﹪, Si:9 ﹪, Zn:4 ﹪, La:0.7 ﹪, Cu:0.98 ﹪, Mg0.67 ﹪, Ag0.66 ﹪, Cd:0.45 ﹪, Zr:0.076 ﹪, V:0.018 ﹪, B:0.027 ﹪, surplus is Ti and inevitable impurity;
Cast titanium alloy impeller preparation method: comprise the following steps: according to aforementioned proportion alloyage, alloy material melting, cast: smelting temperature: 1816 DEG C, pouring temperature is 1757 DEG C; After the demoulding, the impeller obtained is heat-treated: first heated by impeller, is warming up to 900 DEG C, heating rate 300 DEG C/h, be incubated 5 hours, after be cooled to 600 DEG C, rate of temperature fall 100 DEG C/h, be incubated 7 hours, after be warming up to 750 DEG C, heating rate 100 DEG C/h, be incubated 3 hours, after be again cooled to 400 DEG C, rate of temperature fall 50 DEG C/h, be incubated 8 hours, after be again cooled to 200 DEG C, rate of temperature fall 40 DEG C/h, be incubated 5 hours, rear air cooling is to room temperature
Afterwards pickling and Passivation Treatment are carried out to impeller surface, wherein:
Pickle consists of (weight): take 98% dense H 2sO 432 parts, the HCL of 36.5% 8 parts, propanoic acid 8 parts, ethylenediamine 4 parts, alkyl imidazoline quaternary ammonium salt 14 parts; 19 parts, water;
Passivating solution consists of (weight): polyimides 2.8 parts, 2-(3,4-epoxycyclohexyl) ethyl trimethoxy silane 8 parts, N-(2-amino-ethyl)-3-amino propyl methyl dimethoxysilane 14 parts, Sodium fluoroborate 12.7 parts, 3.5 parts, sulphuric acid, dialkyl dithiophosphoric acid oxygen molybdenum 24 parts, 32 parts, water;
Shelling-out of titanium carbide series ceramic material is carried out to the impeller after passivation, titanium carbide series ceramic material layer is formed by being coated in impeller surface, titanium carbide series ceramic material layer thickness 0.4mm, titanium carbide series ceramic material composition of layer comprises (weight): titanium carbide 46 parts, titanium nitride 14 parts, chromium carbide 8 parts, silicon oxide 4.7 parts, impeller after coating is heated, be warming up to 700 DEG C, heating rate 200 DEG C/h, be incubated 3 hours, after be cooled to 500 DEG C, rate of temperature fall 100 DEG C/h, be incubated 7 hours, after be again cooled to 200 DEG C, rate of temperature fall 50 DEG C/h, be incubated 10 hours, rear air cooling is to room temperature, obtain final impeller.

Claims (10)

1. a medical intracardiac pump device, it impeller comprising a pump housing and be installed on pump body, the pump housing comprises: the zirconium oxide series ceramic material layer of the cast titanium alloy pump housing, pump housing outer surface and the titanium oxide base ceramic material layer of pump housing inner surface, impeller comprises the titanium carbide series ceramic material layer on cast titanium alloy impeller and cast titanium alloy impeller outer surface
It is characterized in that, cast titanium alloy pump housing chemical composition is (percentage by weight): Fe:10-12 ﹪, Al:8-9 ﹪, Si:5-6 ﹪, Zn:2-3 ﹪, Mg 1-2 ﹪, Y:0.3-0.4 ﹪, Cu:0.8-0.9 ﹪, Cd:0.2-0.3 ﹪, Zr:0.07-0.08 ﹪, V:0.06-0.07 ﹪, B:0.08-0.09 ﹪, surplus is Ti and inevitable impurity;
Cast titanium alloy pump housing preparation method: comprise the following steps: according to aforementioned proportion alloyage, alloy material melting, cast: smelting temperature: 1810-1820 DEG C, pouring temperature is 1750-1760 DEG C; After the demoulding, the pump housing obtained is heat-treated: first heated by the pump housing, is warming up to 900 DEG C, heating rate 300 DEG C/h, be incubated 5 hours, after be cooled to 600 DEG C, rate of temperature fall 100 DEG C/h, be incubated 7 hours, after be warming up to 750 DEG C, heating rate 100 DEG C/h, be incubated 3 hours, after be again cooled to 400 DEG C, rate of temperature fall 50 DEG C/h, be incubated 8 hours, after be again cooled to 200 DEG C, rate of temperature fall 40 DEG C/h, be incubated 5 hours, rear air cooling is to room temperature
Afterwards pickling and Passivation Treatment are carried out to pump housing surface, wherein:
Pickle consists of (weight): take 98% dense H 2sO 410-35 part, HCL 1-10 part of 36.5%, propanoic acid 5-10 part, ethylenediamine 1-5 part, alkyl imidazoline quaternary ammonium salt 10-15 part; Water 10-20 part;
Passivating solution consists of (weight): polyimides 1-3 part, 2-(3,4-epoxycyclohexyl) ethyl trimethoxy silane 4-10 part, N-(2-amino-ethyl)-3-amino propyl methyl dimethoxysilane 8-15 part, Sodium fluoroborate 10-13 part, sulphuric acid 1-4 part, dialkyl dithiophosphoric acid oxygen molybdenum 20-25 part, water 25-35 part;
Coated with zirconia series ceramic material is carried out to pump housing outer surface after passivation; Zirconium oxide series ceramic material layer is formed by being coated in pump housing outer surface, zirconium oxide series ceramic material layer thickness 0.4mm, zirconium oxide series ceramic material composition of layer comprises (weight): zirconium oxide 70-80 part, titanium boride 30-40 part, tungsten carbide 20-30 part, silicon oxide 1-2 part, the pump housing after coating is heated, be warming up to 800 DEG C, heating rate 250 DEG C/h, be incubated 5 hours, after be cooled to 600 DEG C, rate of temperature fall 100 DEG C/h, is incubated 4 hours, after be again cooled to 300 DEG C, rate of temperature fall 75 DEG C/h, be incubated 8 hours, rear air cooling is to room temperature
Afterwards coated with titanium oxide series ceramic material is carried out to pump housing inner surface, titanium oxide base ceramic material layer is formed by being coated in pump housing inner surface, titanium oxide base ceramic material layer thickness 0.5mm, titanium oxide base ceramic material composition of layer comprises (weight): titanium oxide 50-60 part, titanium nitride 20-30 part, chromium carbide 5-10 part, silicon oxide 1-2 part, the pump housing after coating is heated, be warming up to 700 DEG C, heating rate 200 DEG C/h, be incubated 3 hours, after be cooled to 500 DEG C, rate of temperature fall 100 DEG C/h, be incubated 7 hours, after be again cooled to 200 DEG C, rate of temperature fall 50 DEG C/h, be incubated 10 hours, rear air cooling is to room temperature, obtain the final pump housing,
Cast titanium alloy impeller chemical composition is (percentage by weight): Fe:10-15 ﹪, Al:10-13 ﹪, Si:5-10 ﹪, Zn:1-5 ﹪, La:0.5-0.8 ﹪, Cu:0.8-1 ﹪, Mg0.5-0.7 ﹪, Ag0.5-0.7 ﹪, Cd:0.3-0.5 ﹪, Zr:0.05-0.08 ﹪, V:0.01-0.02 ﹪, B:0.02-0.03 ﹪, surplus is Ti and inevitable impurity;
Cast titanium alloy impeller preparation method: comprise the following steps: according to aforementioned proportion alloyage, alloy material melting, cast: smelting temperature: 1810-1820 DEG C, pouring temperature is 1750-1760 DEG C; After the demoulding, the impeller obtained is heat-treated: first heated by impeller, is warming up to 900 DEG C, heating rate 300 DEG C/h, be incubated 5 hours, after be cooled to 600 DEG C, rate of temperature fall 100 DEG C/h, be incubated 7 hours, after be warming up to 750 DEG C, heating rate 100 DEG C/h, be incubated 3 hours, after be again cooled to 400 DEG C, rate of temperature fall 50 DEG C/h, be incubated 8 hours, after be again cooled to 200 DEG C, rate of temperature fall 40 DEG C/h, be incubated 5 hours, rear air cooling is to room temperature
Afterwards pickling and Passivation Treatment are carried out to impeller surface, wherein:
Pickle consists of (weight): take 98% dense H 2sO 410-35 part, HCL 1-10 part of 36.5%, propanoic acid 5-10 part, ethylenediamine 1-5 part, alkyl imidazoline quaternary ammonium salt 10-15 part; Water 10-20 part;
Passivating solution consists of (weight): polyimides 1-3 part, 2-(3,4-epoxycyclohexyl) ethyl trimethoxy silane 4-10 part, N-(2-amino-ethyl)-3-amino propyl methyl dimethoxysilane 8-15 part, Sodium fluoroborate 10-13 part, sulphuric acid 1-4 part, dialkyl dithiophosphoric acid oxygen molybdenum 20-25 part, water 25-35 part;
Shelling-out of titanium carbide series ceramic material is carried out to the impeller after passivation, titanium carbide series ceramic material layer is formed by being coated in impeller surface, titanium carbide series ceramic material layer thickness 0.4mm, titanium carbide series ceramic material composition of layer comprises (weight): titanium carbide 40-50 part, titanium nitride 10-15 part, chromium carbide 8 parts, silicon oxide 3-5 part, impeller after coating is heated, be warming up to 700 DEG C, heating rate 200 DEG C/h, be incubated 3 hours, after be cooled to 500 DEG C, rate of temperature fall 100 DEG C/h, be incubated 7 hours, after be again cooled to 200 DEG C, rate of temperature fall 50 DEG C/h, be incubated 10 hours, rear air cooling is to room temperature, obtain final impeller.
2. a kind of medical intracardiac pump device as claimed in claim 1, cast titanium alloy pump housing chemical composition is: Fe:10 ﹪, Al:8 ﹪, Si:5 ﹪, Zn:2 ﹪, Mg 1 ﹪, Y:0.3 ﹪, Cu:0.8 ﹪, Cd:0.2 ﹪, Zr:0.07 ﹪, V:0.06 ﹪, B:0.08 ﹪, surplus is Ti and inevitable impurity.
3. a kind of medical intracardiac pump device as claimed in claim 1, cast titanium alloy pump housing chemical composition is: Fe:12 ﹪, Al:9 ﹪, Si:6 ﹪, Zn:3 ﹪, Mg 2 ﹪, Y:0.4 ﹪, Cu:0.9 ﹪, Cd:0.3 ﹪, Zr:0.08 ﹪, V:0.07 ﹪, B:0.09 ﹪, surplus is Ti and inevitable impurity.
4. a kind of medical intracardiac pump device as claimed in claim 1, cast titanium alloy pump housing chemical composition is: Fe:11 ﹪, Al:8.5 ﹪, Si:5.5 ﹪, Zn:2.5 ﹪, Mg 1.5 ﹪, Y:0.35 ﹪, Cu:0.85 ﹪, Cd:0.25 ﹪, Zr:0.075 ﹪, V:0.065 ﹪, B:0.085 ﹪, surplus is Ti and inevitable impurity.
5. a kind of medical intracardiac pump device as claimed in claim 1, cast titanium alloy impeller chemical composition is (weight): Fe:10 ﹪, Al:10 ﹪, Si:5 ﹪, Zn:1 ﹪, La:0.5 ﹪, Cu:0.8 ﹪, Mg0.5 ﹪, Ag0.5 ﹪, Cd:0.3 ﹪, Zr:0.05 ﹪, V:0.01 ﹪, B:0.02 ﹪, surplus is Ti and inevitable impurity.
6. a kind of medical intracardiac pump device as claimed in claim 1, cast titanium alloy impeller chemical composition is (weight): Fe:15 ﹪, Al:13 ﹪, Si:10 ﹪, Zn:5 ﹪, La:0.8 ﹪, Cu:1 ﹪, Mg0.7 ﹪, Ag0.7 ﹪, Cd:0.5 ﹪, Zr:0.08 ﹪, V:0.02 ﹪, B:0.03 ﹪, surplus is Ti and inevitable impurity.
7. the manufacture method of a kind of medical intracardiac pump device as claimed in claim 1, cast titanium alloy impeller chemical composition is (weight): Fe:13 ﹪, Al:11 ﹪, Si:7 ﹪, Zn:3 ﹪, La:0.6 ﹪, Cu:0.9 ﹪, Mg 0.6 ﹪, Ag 0.6 ﹪, Cd:0.4 ﹪, Zr:0.06 ﹪, V:0.015 ﹪, B:0.025 ﹪, surplus is Ti and inevitable impurity.
8. the manufacture method of a kind of medical intracardiac pump device as claimed in claim 1, zirconium oxide series ceramic material composition of layer comprises (weight): zirconium oxide 75 parts, titanium boride 35 parts, tungsten carbide 25 parts, silicon oxide 1.5 parts.
9. the manufacture method of a kind of medical intracardiac pump device as claimed in claim 1, titanium oxide base ceramic material composition of layer comprises (weight): titanium oxide 55 parts, titanium nitride 25 parts, chromium carbide 7 parts, silicon oxide 1.5 parts.
10. a kind of medical intracardiac pump device as claimed in claim 1, titanium carbide series ceramic material composition of layer comprises (weight): titanium carbide 45 parts, titanium nitride 13 parts, chromium carbide 8 parts, silicon oxide 4 parts.
CN201510190152.7A 2015-04-21 2015-04-21 Medical intracardiac pump device Pending CN104857583A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201510190152.7A CN104857583A (en) 2015-04-21 2015-04-21 Medical intracardiac pump device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201510190152.7A CN104857583A (en) 2015-04-21 2015-04-21 Medical intracardiac pump device

Publications (1)

Publication Number Publication Date
CN104857583A true CN104857583A (en) 2015-08-26

Family

ID=53904032

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201510190152.7A Pending CN104857583A (en) 2015-04-21 2015-04-21 Medical intracardiac pump device

Country Status (1)

Country Link
CN (1) CN104857583A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105400991A (en) * 2015-12-18 2016-03-16 常熟市中科电机有限公司 Motor

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5676632A (en) * 1989-12-21 1997-10-14 Smith & Nephew Richards, Inc. Ventricular assist devices of enhanced hemocompatibility
CN103331584A (en) * 2013-07-16 2013-10-02 富威科技（吴江）有限公司 Manufacturing technology of copper strip for photovoltaic solar device
CN104245975A (en) * 2011-11-10 2014-12-24 法国雷恩国立应用科学学院 Method for manufacturing a titanium alloy for biomedical devices

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5676632A (en) * 1989-12-21 1997-10-14 Smith & Nephew Richards, Inc. Ventricular assist devices of enhanced hemocompatibility
CN104245975A (en) * 2011-11-10 2014-12-24 法国雷恩国立应用科学学院 Method for manufacturing a titanium alloy for biomedical devices
CN103331584A (en) * 2013-07-16 2013-10-02 富威科技（吴江）有限公司 Manufacturing technology of copper strip for photovoltaic solar device

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105400991A (en) * 2015-12-18 2016-03-16 常熟市中科电机有限公司 Motor

Similar Documents

Publication Publication Date Title
CN104862528B (en) A kind of blood pump in operative cardiac
CN104771797A (en) Blood pump in heart
CN104762532B (en) A kind of acid and alkali-resistance chemical pump
CN106151467B (en) A kind of aluminium alloy gear box
CN106086523A (en) A kind of vane type fire pump of corrosion-resistant high-temperature antiscale low cost
CN105063538B (en) A kind of high aluminium thermal spraying solid core wire material and preparation method and application
CN104762528A (en) Impeller for medical apparatus blood pump
CN104857583A (en) Medical intracardiac pump device
CN104740705A (en) Implantable blood pump body of medical mechanism
CN104740704A (en) Medical mechanical micro-power pump for treating cardiovascular disease
CN107267821A (en) A kind of knife handle weld jig
CN104740706A (en) Blood pump of medical mechanism
CN104740701A (en) Medical cardiac pump body
CN104745904A (en) Oil delivery pump for oil refinery
CN104831121B (en) A kind of cardiovascular power pump
CN105385862B (en) A kind of preparation method of medical artifucial limb
CN101838762B (en) High-hardness corrosion resistant 7000 series aluminum alloy and production method thereof
CN104862527A (en) Medical heart pump impeller
CN114225120B (en) Degradable pure magnesium or magnesium alloy oral biological barrier film and preparation method thereof
CN105756992A (en) Anti-corrosion, anti-abrasion, high-temperature-resistant, anti-scaling, low-cost and high-cleanliness water pump for automobile
CN101122042A (en) Method for preparing hydroxyapatite nano composite coat with gradient function
CN104806556A (en) Heat supply circulating water pump
CN115948676B (en) Self-adaptive implant for bone mass deficiency, titanium-zirconium-iron alloy and preparation method thereof
CN105163540A (en) Surface treatment method for die-casting aluminum alloy, die-casting aluminum alloy, and mobile terminal housing
CN104826176A (en) Orthopaedic medical instrument tibial bone plate

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
EXSB Decision made by sipo to initiate substantive examination
SE01 Entry into force of request for substantive examination
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20150826

WD01 Invention patent application deemed withdrawn after publication