CN104857446B - It is a kind of to treat cardiopathic Chinese medicine and preparation method thereof - Google Patents
It is a kind of to treat cardiopathic Chinese medicine and preparation method thereof Download PDFInfo
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Abstract
Cardiopathic Chinese medicine is treated the present invention provides a kind of, the cardiopathic Chinese medicine for the treatment of is that 30 50g of grass-leaved sweetflag, 5 12g of Chinese cassia tree, 3 30g of rheum officinale, 1 10g of Schisandra chinensis, 2 10g of agaric, 1 8g of Chinese yam, 30 50g of ilex pubescens, 1 5g of styrax, 5 15g of fructus cannabis, 1 10g of Radix Curcumae and 1 15g of lotus seeds are formed by raw material.Chinese cassia tree, rheum officinale, ilex pubescens in the cardiopathic Chinese medicine for the treatment of provided by the invention have effects that warming meridian, promoting blood circulation dredge arteries and veins, can play the role of dredging the scattered stasis of blood, so as to improve the blood supply (oxygen) of brain tissue；Grass-leaved sweetflag, Chinese yam have effects that distend the blood vessels, so as to improve the blood flow for entering heart；Schisandra chinensis, fructus cannabis, lotus seeds have effects that calming heart, QI invigorating, mental-tranquilization, can hold the mind, reduce palpitaition；Radix Curcumae have effects that promoting blood circulation, promoting qi circulation and removing obstruction in the collateral, can eliminate it is uncomfortable in chest pained caused by heart disease, solve the problems, such as treatment heart disease weak curative effect.
Description
Technical field
The present invention relates to the field of Chinese medicines, more specifically, are related to a kind for the treatment of cardiopathic Chinese medicine and preparation method thereof.
Background technology
Heart disease is a kind of relatively common circulation system disease, and the circulatory system is by heart, blood vessel and adjusts blood circulation
Neurohumor organizational composition, therefore circulation system disease is also referred to as cardiovascular disease, wherein the most common with heart disease.Heart disease
Be divided into congenital heart disease and acquired heart disease, wherein congenital heart disease be due to heart in foetal period dysplasia
It is caused；Acquired heart disease is caused by being acted on by external or body internal factor after being born, such as coronary atherosclerotic
Heart disease, rheumatic heart disease, hypertensive cardiopathy, cor pulmonale and hemopathic heart disease etc., wherein hypertension
It is cardiopathic Etiological in recent years.Heart disease is frequently accompanied by palpitaition, expiratory dyspnea, cough, spitting of blood, pectoralgia in breaking-out
Etc. symptoms, and have abnormal heart sound, arrhythmia cordis, cacosphyxia etc..The patient's disability having a heart disease gives family
Serious burden is brought with individual.
It is mostly currently on the market Western medicine as cardiopathic drug is treated, though Western medicine drug effect is fast, there are human bodies to be easy
Generation drug resistance, drug have the shortcomings that toxicity, drug easily cause arrhythmia cordis, because being unable to preferably treat heart
Disease.Chinese medicine has a lot as treatment cardiotropic formulation, but that there are pharmacological properties mostly is single, can not integrally improve body, effect list
One, the problem of weak curative effect, drug purification, processing complexity etc., thus limit development of the Chinese medicine in treatment heart disease.
Invention content
Cardiopathic Chinese medicine and preparation method thereof is treated the object of the present invention is to provide a kind of, to solve described in background technology
Treatment heart disease weak curative effect the problem of.
In order to solve the above technical problem, the present invention provides following technical solutions：
A kind of to treat cardiopathic Chinese medicine, the cardiopathic Chinese medicine material for the treatment of is grass-leaved sweetflag 30-50g, Chinese cassia tree 5-
12g, rheum officinale 3-30g, Schisandra chinensis 1-10g, agaric 2-10g, Chinese yam 1-8g, ilex pubescens 30-50g, styrax 1-5g, fructus cannabis 5-
15g, Radix Curcumae 1-10g and lotus seeds 1-15g.
Preferably, the cardiopathic Chinese medicine material for the treatment of is grass-leaved sweetflag 40-50g, Chinese cassia tree 8-12g, rheum officinale 20-30g, five
Taste 1-3g, agaric 4-10g, Chinese yam 3-8g, ilex pubescens 40-50g, styrax 1-3g, fructus cannabis 9-15g, Radix Curcumae 3-10g and lotus
Sub- 6-15g.
Preferably, the cardiopathic Chinese medicine material of the treatment be grass-leaved sweetflag 50g, Chinese cassia tree 12g, rheum officinale 30g, Schisandra chinensis 1g,
Agaric 10g, Chinese yam 8g, ilex pubescens 50g, styrax 1g, fructus cannabis 15g, Radix Curcumae 10g and lotus seeds 15g.
A kind of preparation method of preparation method that treating cardiopathic Chinese medicine includes：
S01：By grass-leaved sweetflag, Chinese cassia tree, rheum officinale, Schisandra chinensis, agaric, Chinese yam, ilex pubescens, styrax, fructus cannabis, Radix Curcumae and lotus
Sub- impurity elimination is cleaned, dries, is spare；
S02：It weighs to raw material according to the ratio in formula；
S03：By the grass-leaved sweetflag after weighing, Chinese cassia tree, rheum officinale, Schisandra chinensis, agaric, Chinese yam, ilex pubescens, styrax, fructus cannabis,
Radix Curcumae and lotus seeds are added to the water decoction three times, obtain three parts of decoction liquors；
S04：Three parts of decoction liquors in step S03 are merged, and are filtered, herb liquid is obtained；
S05：By herb liquid heating, concentration, dry, grinding, traditional Chinese medicine powder is obtained.
Preferably, in the step S03：First time amount of water is 8 times of raw material gross weight, is decocted 3 hours；After filtering,
In filter residue plus water, second of amount of water decocted are 5 times of raw material gross weight, are decocted 2 hours；After filtering, water is added in filter residue, the
The amount of water decocted three times is 3 times of raw material gross weight, is decocted 1 hour.
Each raw material act as in the cardiopathic Chinese medicine for the treatment of provided by the invention：
Grass-leaved sweetflag：Essential Oil of Acorus tatarinowii (beta-Asarone) plays the role of making coronary vasodilation under a certain concentration, clinical
It is usually used in the treatment that coronary heart disease, pulmonary heart disease etc. belong to the stagnant obstruction of qi in the chest person of phlegm foul smell.
Chinese cassia tree：Acrid flavour, sweet, extremely hot in nature have the effect of mends fire supporing yang, guiding fire to origin, eliminating cold to stop pain, warming meridian, main
Control labor product it is deficient, tidal air is few, and action is panted, palpitation with fear of having a guilty conscience, and dry throat lip is dry.《The formulary of peaceful benevolent dispensary》Described in Chinese cassia tree tool
There are blood-enrich, the effect of mental-tranquilization.
Rheum officinale：Bitter, it is cold in nature, it is nontoxic, have and purge heat logical intestines, the effect of removing pattogenic heat from the blood and toxic material from the body, dispelling stasis of blood and stimulating the menstrual flow, cure mainly hypertension,
Hyperlipidemia and artery sclerosis.
Schisandra chinensis：It is sour, sweet, it is warm-natured, there is the effect of convergence astringent method, supplementing qi and promoting the production of body fluid, tonifying kidney and calming nerves, cure mainly void of coughing long
Asthma, emission, enuresis frequent micturition, endless diarrhea, spontaneous sweating, injury thirst, Heat Diabetes, palpitation and insomnia.
Agaric：It is sweet in flavor, it is mild-natured, there is benefiting qi and nourishing blood, moistening lung to stop blooding, decompression the effect of anticancer, cures mainly Qi and blood deficiency, and four
Limb is twitched, chronic cough of deficiency lung, is spat blood, and is spitted blood, bleeding from five sense organs or subcutaneous tissue, bloody flux, hemorrhoid hemorrhage, woman uterine bleeding, high blood pressure, constipation, fundus hemorrhage,
Sub- Cervical cancer, carcinoma of vagina, traumatic injury.
Chinese yam：Sweet, flat, nontoxic, contained dopamine has expansion blood vessel, improves sanguimotor critical function.
Ilex pubescens：With clearing heat and detoxicating, the effect of blood circulation and channel invigorating, anemopyretic cold is cured mainly, dyspnea and cough due to lung-heat, laryngeal edema is flat
Peach body is scorching, dysentery, coronary heart disease, the hemiplegia caused by cerebrovascular accident, Buerger's disease, erysipelas, scald, centrality view
Film inflammation, uveitis and skin acute suppurative inflammation, coronary arteriosclerotic cardiopathy, acute myocardial infarction, blood column close
Plug property vasculitis；Burn, pernio are controlled in external application.
Styrax：With opening surreptitiously clear god, the effect of the promoting flow of qi and blood circulation, analgesic, apoplexy coma due to blocking of the respiratory system is cured mainly, bstruction of the circulation of vital energy is fainted cruelly, middle evils be confused
Fan, trusted subordinate's pain, postpartum anemic fainting, child convulsion.
Fructus cannabis：It is sweet in flavor, it is mild-natured, there is the effect of beneficial spleen qi-restoratives of energy, nourishing yin to moisten dryness, defaecation, cure mainly tinea pedis and swell and ache, is physically weak
Early ageing, insufficiency of heart yin, palpitation and restlessness, deficiency of blood Tianjin wound, dry constipation of intestines etc..
Radix Curcumae：It is pungent, bitter, it trembles with fear, with the effect of promoting blood circulation and stopping pain, promoting qi circulation and removing obstruction in the collateral, clear away heart-fire cool blood, normalizing gallbladder to cure jaundice, cures mainly chest side of body
Shouting pain, chest impediment and cardialgia, closed dysmenorrhea, swollen breasts, pyreticosis coma, epilepsy are gone mad, blood-head tells nosebleed, jaundice.
Lotus seeds：It is sweet in flavor, puckery, it is mild-natured, there is the effect of tonifying spleen and stopping diarrhea, stop-band, the puckery essence of kidney-nourishing, mental-tranquilization, cure mainly spleen deficiency
Diarrhea, under, seminal emission, palpitation and insomnia.
There is warming meridian, promoting blood circulation to dredge arteries and veins for Chinese cassia tree, rheum officinale, ilex pubescens in the cardiopathic Chinese medicine for the treatment of provided by the invention
The effect of, it can play the role of dredging the scattered stasis of blood, so as to improve the blood supply and oxygen supply of brain tissue；Grass-leaved sweetflag, Chinese yam have make
The effect of blood vessel dilatation, so as to improve the blood flow for entering heart；Schisandra chinensis, fructus cannabis, lotus seeds have calming heart, QI invigorating,
The effect of mental-tranquilization, can hold the mind, reduce palpitaition；Radix Curcumae has effects that promoting blood circulation, promoting qi circulation and removing obstruction in the collateral, can eliminate heart
Uncomfortable in chest pained caused by disease, therefore, each raw material in the present invention passes through reasonable compatibility, and it is distinctive to give full play to each raw material itself
While performance and effect, the complementation between having taken into account, drug effect complements each other, disease treatment significant effect,
And have no toxic side effect, solve the problems, such as treatment heart disease weak curative effect.
Description of the drawings
To describe the technical solutions in the embodiments of the present invention more clearly, make required in being described below to embodiment
Attached drawing is briefly described, it should be apparent that, for those of ordinary skills, do not making the creative labor
Under the premise of, it can also be obtained according to these attached drawings other attached drawings.
Fig. 1 is the preparation flow figure of the cardiopathic Chinese medicine for the treatment of provided in an embodiment of the present invention.
Specific implementation mode
Cardiopathic Chinese medicine for the treatment of provided in an embodiment of the present invention and preparation method thereof, solves treatment heart disease weak curative effect
The problem of.
In order to make those skilled in the art more fully understand the technical solution in the embodiment of the present invention, and make of the invention real
The above objects, features, and advantages for applying example can be more obvious and easy to understand, below in conjunction with the accompanying drawings to the technology in the embodiment of the present invention
Scheme is described in further detail.
The preparation method of the cardiopathic Chinese medicine for the treatment of provided by the invention please refers to attached drawing 1, the preparation method of each embodiment
Unanimously, here, only the preparation method of embodiment 1 is described, the preparation method is the same as that of Example 1 for remaining embodiment.
Embodiment 1
The constituent of the cardiopathic Chinese medicine for the treatment of provided in an embodiment of the present invention is：
Grass-leaved sweetflag 50g, Chinese cassia tree 12g, rheum officinale 30g, Schisandra chinensis 1g, agaric 10g, Chinese yam 8g, ilex pubescens 50g, styrax 1g,
Fructus cannabis 15g, Radix Curcumae 10g, lotus seeds 15g.
The preparation method of the cardiopathic Chinese medicine for the treatment of provided in an embodiment of the present invention includes：
S01：By grass-leaved sweetflag, Chinese cassia tree, rheum officinale, Schisandra chinensis, agaric, Chinese yam, ilex pubescens, styrax, fructus cannabis, Radix Curcumae and lotus
Son removal impurity, cleans up, is then placed in drying box and dries, spare；
S02：It weighs to raw material according to the ratio in formula；
S03：By the grass-leaved sweetflag after weighing, Chinese cassia tree, rheum officinale, Schisandra chinensis, agaric, Chinese yam, ilex pubescens, styrax, fructus cannabis,
Radix Curcumae and lotus seeds are added to the water decoction three times, and the amount of water decocted for the first time is 8 times of raw material gross weight, is decocted 3 hours；Filtering
Afterwards, it is 5 times of raw material gross weight that water, second of amount of water decocted are added in filter residue, is decocted 2 hours；After filtering, add in filter residue
Water, the amount of water that third time decocts are 3 times of raw material gross weight, decoct 1 hour, obtain three parts of decoction liquors；
S04：Three parts of decoction liquors in step S03 are merged, and filter out impurity, obtain herb liquid；
S05：It is heated at being 70 DEG C in temperature by herb liquid, and stirs concentration, ground after dry in drying box, in obtaining
Medicinal powder.
Embodiment 2
The constituent of the cardiopathic Chinese medicine for the treatment of provided in an embodiment of the present invention is：
Grass-leaved sweetflag 30g, Chinese cassia tree 5g, rheum officinale 20g, Schisandra chinensis 10g, agaric 4g, Chinese yam 3g, ilex pubescens 40g, styrax 3g,
Fructus cannabis 9g, Radix Curcumae 3g, lotus seeds 1g.
The preparation method is the same as that of Example 1 for the cardiopathic Chinese medicine for the treatment of provided in an embodiment of the present invention.
Embodiment 3
The constituent of the cardiopathic Chinese medicine for the treatment of provided in an embodiment of the present invention is：
Grass-leaved sweetflag 40g, Chinese cassia tree 8g, rheum officinale 3g, Schisandra chinensis 3g, agaric 2g, Chinese yam 1g, ilex pubescens 30g, styrax 5g, fire
Edestan 5g, Radix Curcumae 1g, lotus seeds 6g.
The preparation method is the same as that of Example 1 for the cardiopathic Chinese medicine for the treatment of provided in an embodiment of the present invention.
Embodiment 4
The constituent of the cardiopathic Chinese medicine for the treatment of provided in an embodiment of the present invention is：
Grass-leaved sweetflag 35g, Chinese cassia tree 10g, rheum officinale 15g, Schisandra chinensis 5g, agaric 8g, Chinese yam 5g, ilex pubescens 45g, styrax 2g,
Fructus cannabis 10g, Radix Curcumae 5g, lotus seeds 7g.
The preparation method is the same as that of Example 1 for the cardiopathic Chinese medicine for the treatment of provided in an embodiment of the present invention.
Embodiment 5
The constituent of the cardiopathic Chinese medicine for the treatment of provided in an embodiment of the present invention is：
Grass-leaved sweetflag 45g, Chinese cassia tree 7g, rheum officinale 25g, Schisandra chinensis 7g, agaric 7g, Chinese yam 6g, ilex pubescens 35g, styrax 4g, fire
Edestan 8g, Radix Curcumae 4g, lotus seeds 8g.
The preparation method is the same as that of Example 1 for the cardiopathic Chinese medicine for the treatment of provided in an embodiment of the present invention.
Clinical test
1, case selection
Test group：It is 50, age 35-65 Sui, 55 years old average, course of disease 2-10；
Control group：It is 50, age 35-65 Sui, 55 years old average, course of disease 2-10.
The degrees of symptoms of test group and two groups of cases of control group is almost the same, and no significant difference is comparable.
2, administering mode
Test group：The cardiopathic Chinese medicine for the treatment of prepared using the embodiment of the present invention 1, twice daily, warm water is taken after mixing it with water after meal,
A month as a course for the treatment of, and two courses for the treatment of are used continuously；
Control group：Oral nitroglycerin class drug, three times a day, warm water is taken after mixing it with water after meal, and a month as a course for the treatment of, is continuously made
With two courses for the treatment of.
3, clinical symptoms
Palpitaition, weak, aversion to cold and cold limbs, feeling of oppression and pain in the chest, dark tongue quality, has ecchymosis, thready and hesitant pulse, pale complexion, insomnia more at shortness of breath
Dream, dysphoria in chestpalms-soles, dryness of the mouth and throat, constipation etc..
4, diagnostic criteria
4.1 recovery from illness：Clinical symptoms completely disappear；
4.2 effective：Clinical symptoms disappear substantially；
4.3 effectively：Clinical symptom relief；
4.4 invalid：Clinical symptoms are substantially unchanged；
5, test result
The comparison of the effect of test group and control group is shown in Table 1.
1 test result of table
| Number of cases | It cures | It is effective | Effectively | In vain | Cure rate | It is efficient | |
| Test group | 50 | 35 | 9 | 4 | 2 | 70% | 96% |
| Control group | 50 | 24 | 8 | 11 | 7 | 48% | 86% |
It can be seen from Table 1 that heart disease can be significantly treated using the cardiopathic Chinese medicine for the treatment of provided by the invention,
Clinical application proves that efficient is 96%, cure rate 70%, compared with the control group, test group treatment is cardiopathic efficient and cures
Rate is relatively high, it can be said that Chinese cassia tree, rheum officinale, the ilex pubescens in the bright cardiopathic Chinese medicine for the treatment of provided by the invention have temperature
The effect of arteries and veins is dredged in qualcomm meridian, promoting blood circulation, can play the role of dredging the scattered stasis of blood, so as to improve the blood supply and oxygen supply of brain tissue；Stone
Calamus, Chinese yam have effects that distend the blood vessels, so as to improve the blood flow for entering heart；Schisandra chinensis, fructus cannabis, lotus seeds
Have effects that calming heart, QI invigorating, mental-tranquilization, the mind can be held, reduces palpitaition；Radix Curcumae has the work(of promoting blood circulation, promoting qi circulation and removing obstruction in the collateral
Effect, can eliminate uncomfortable in chest pained caused by heart disease, and further relating to the cardiopathic Chinese medicine for the treatment of provided by the invention can be effective
Heart disease is treated on ground, and is had no toxic side effect.
The embodiments of the present invention described above are not intended to limit the scope of the present invention.It is any in the present invention
Spirit and principle within made by modifications, equivalent substitutions and improvements etc., should all be included in the protection scope of the present invention.
Claims (5)
1. a kind for the treatment of cardiopathic Chinese medicine, which is characterized in that the cardiopathic Chinese medicine material of the treatment be grass-leaved sweetflag 30-50g,
Chinese cassia tree 5-12g, rheum officinale 3-30g, Schisandra chinensis 1-10g, agaric 2-10g, Chinese yam 1-8g, ilex pubescens 30-50g, styrax 1-5g, fire
Edestan 5-15g, Radix Curcumae 1-10g and lotus seeds 1-15g.
2. the cardiopathic Chinese medicine for the treatment of according to claim 1, which is characterized in that the cardiopathic Chinese medicine material for the treatment of
For grass-leaved sweetflag 40-50g, Chinese cassia tree 8-12g, rheum officinale 20-30g, Schisandra chinensis 1-3g, agaric 4-10g, Chinese yam 3-8g, ilex pubescens 40-
50g, styrax 1-3g, fructus cannabis 9-15g, Radix Curcumae 3-10g and lotus seeds 6-15g.
3. the cardiopathic Chinese medicine for the treatment of according to claim 2, which is characterized in that the cardiopathic Chinese medicine material for the treatment of
For grass-leaved sweetflag 50g, Chinese cassia tree 12g, rheum officinale 30g, Schisandra chinensis 1g, agaric 10g, Chinese yam 8g, ilex pubescens 50g, styrax 1g, fructus cannabis
15g, Radix Curcumae 10g and lotus seeds 15g.
4. a kind of preparation method for treating cardiopathic Chinese medicine, which is characterized in that the cardiopathic Chinese medicinal preparation method for the treatment of
Including：
S01：Grass-leaved sweetflag, Chinese cassia tree, rheum officinale, Schisandra chinensis, agaric, Chinese yam, ilex pubescens, styrax, fructus cannabis, Radix Curcumae and lotus seeds are gone
It is miscellaneous, clean, drying, it is spare；
S02：It weighs to raw material according to any ratio in claim 1-3；
S03：By the grass-leaved sweetflag after weighing, Chinese cassia tree, rheum officinale, Schisandra chinensis, agaric, Chinese yam, ilex pubescens, styrax, fructus cannabis, Radix Curcumae
It is added to the water decoction three times with lotus seeds, obtains three parts of decoction liquors；
S04：Three parts of decoction liquors in step S03 are merged, and are filtered, herb liquid is obtained；
S05：By herb liquid heating, concentration, dry, grinding, traditional Chinese medicine powder is obtained.
5. the preparation method of the cardiopathic Chinese medicine for the treatment of according to claim 4, which is characterized in that the step S03
In：
First time amount of water is 8 times of raw material gross weight, is decocted 3 hours；After filtering, in filter residue plus water, second of decoction add
Water is 5 times of raw material gross weight, is decocted 2 hours；After filtering, in filter residue plus water, the amount of water that third time decocts are that raw material is total
3 times of weight decoct 1 hour.
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| "正交试验优选通脑精胶囊的提取工艺";陈浩等;《中国实验方剂学杂志》;20090531;第15卷(第5期);第30-32页 * |
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