CN104857198A - Traditional Chinese medicinal composition for treating kidney stone and application of composition - Google Patents

Traditional Chinese medicinal composition for treating kidney stone and application of composition Download PDF

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CN104857198A
CN104857198A CN201510335759.XA CN201510335759A CN104857198A CN 104857198 A CN104857198 A CN 104857198A CN 201510335759 A CN201510335759 A CN 201510335759A CN 104857198 A CN104857198 A CN 104857198A
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composition
calculus
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chinese medicine
medicine composition
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产俊涛
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Abstract

The invention discloses a traditional Chinese medicinal composition for treating kidney stone and application of the composition. The traditional Chinese medicinal composition is composed of flowers of india canna, quamoclit herb and dried prunus persica branches. The composition adopts the dried prunus persica branches capable of promoting blood circulation to remove meridian obstruction and removing toxin as a main medicinal material, and adopts the flowers of india canna capable of invigorating blood circulation and stopping bleeding as an auxiliary medicinal material; moreover, the quamoclit herb capable of clearing heat and removing toxin, cooling blood, diminishing inflammation, and eliminating tumescence is added, and all the materials are used together and combined to provide the efficacies of invigorating blood circulation, stopping bleeding, dredging collaterals, diminishing inflammation, eliminating tumescence, removing toxin, and removing urinary calculus. The traditional Chinese medicinal composition has the efficacies of diminishing inflammation, eliminating tumescence, promoting blood circulation to remove blood stasis, stopping bleeding, killing pain, promoting the circulation of qi and removing stasis, promoting diuresis and removing urinary calculus, and is suitable for kidney stone patients suffering from the following symptoms: aching pain of the waist, fatigue of the whole body, unsmooth urination, cruenturesis and the like; the composition is obvious in curative effect, free of toxin and side effects, and low in cost, can obviously relieve the pain suffered by the kidney stone patients, alleviate spasm of the ureter and urethra, and promote the urinary function to become normal, and has the remarkable efficacies of removing urinary calculus and killing pain.

Description

A kind of Chinese medicine composition and application thereof being used for the treatment of renal calculus
Technical field
The present invention relates to medical art, specifically a kind of Chinese medicine composition and application thereof being used for the treatment of renal calculus.
Background technology
Renal calculus is a kind of frequently-occurring disease, commonly encountered diseases, clinical with renal colic and hematuria for cardinal symptom, often can cause urinary tract obstruction, and secondary infection.At present, the medicine of clinical treatment renal calculus is more, but due to the structure of kidney special, the effect of Drug therapy and the fossil lithodialysis function of medicine not satisfactory, most patient must not proceed to operative treatment then; And operative treatment is often with side effect such as drug allergy, operation wound is large, and treatment time is long, postoperative easy recurrence, and financial expenditure is large, brings serious economy and body burden to sufferer.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine composition and the application thereof that are used for the treatment of renal calculus, to solve the problem.
For achieving the above object, the invention provides following technical scheme:
Be used for the treatment of a Chinese medicine composition for renal calculus, be made up of Flos Cannae Indicae, cypress vine herb and Ramulus Persicae.
As the further scheme of the present invention: be made up of Flos Cannae Indicae 4-7 part, cypress vine herb 1-2 part and Ramulus Persicae 6-10 part according to the raw material of mass fraction.
The described Chinese medicine composition being used for the treatment of renal calculus is applied on the medicine of preparation treatment renal calculus.
As the further scheme of the present invention: described Chinese medicine composition is oral formulations.
As the further scheme of the present invention: described oral formulations is oral liquid, granule, pill or capsule.
Compared with prior art, the invention has the beneficial effects as follows: the present invention with the Ramulus Persicae of promoting blood circulation to remove obstruction in the collateral, removing toxic substances for principal agent, with the Flos Cannae Indicae of promoting blood circulation and hemostasis for accessory drugs, in addition the cypress vine herb of heat-clearing and toxic substances removing, removing heat from blood, anti-inflammation detumescence, all medicines share, and play promoting blood circulation and hemostasis, dredging collateral, antiinflammatory, detumescence, removing toxic substances, calculus removing effect altogether.The present invention has effect of anti-inflammation detumescence, blood circulation promoting and blood stasis dispelling, hemostasis and pain-relieving, promoting QI to circulate and dispersing the agglomeration of the pathogens, diuresis and expelling stone, is applicable to the renal calculus patient of the symptoms such as waist is ached, the whole body is weak, it is not smooth to urinate, hematuria, and evident in efficacy, has no side effect, with low cost; Compatibility science of the present invention, obviously can alleviate the pain of renal calculus patient, make ureter, the spasm of urethra alleviated, and impels urinary function normal, has significant calculus, pain palliation efficacy.
Detailed description of the invention
Below in conjunction with the embodiment of the present invention, be clearly and completely described the technical scheme in the embodiment of the present invention, obviously, described embodiment is only the present invention's part embodiment, instead of whole embodiments.Based on the embodiment in the present invention, those of ordinary skill in the art, not making the every other embodiment obtained under creative work prerequisite, belong to the scope of protection of the invention.
Embodiment 1
In the embodiment of the present invention, a kind of Chinese medicine composition being used for the treatment of renal calculus, is made up of Flos Cannae Indicae 4kg, cypress vine herb 1kg and Ramulus Persicae 10kg according to quality meter.
The described Chinese medicine composition being used for the treatment of renal calculus is oral liquid, and its preparation method is:
(1) take Flos Cannae Indicae, cypress vine herb and Ramulus Persicae by above-mentioned quality, clean decontamination, dry, be ground into graininess;
(2) the graininess medical material of step (1) is soaked 2h, the water surface covers medical material surface 3cm;
(3) pull soaked medical material out, decoct with water twice, add the water of 10 times amount of medical material total amount for the first time, decoct 4h, filter and obtain filtrate one and filtering residue one, filtrate one is for subsequent use; Second time adds the water of 8 times amount of medical material total amount in filtering residue one, decocts 2h, and filter and obtain filtrate two and filtering residue two, filtrate two is for subsequent use; Merge twice filtrate, again filter, when being concentrated into 90 DEG C, relative density is the concentrated solution of 1.1g/ml;
(4) concentrated solution is placed in cold preservation 24h under 0-3 DEG C of cryogenic conditions, then toward the filter aid kieselguhr wherein adding 0.3wt%, filters and obtain filtrate, again filtrate is concentrated into every milliliter containing 2.5g crude drug amount, be placed in cold preservation 24h under 0-3 DEG C of cryogenic conditions, filter, obtain oral liquid.
The instructions of taking of the Chinese medicine composition of the embodiment of the present invention: for oral administration, once a day, each 5ml 15 days is a course for the treatment of.
Embodiment 2
In the embodiment of the present invention, a kind of Chinese medicine composition being used for the treatment of renal calculus, is made up of Flos Cannae Indicae 7kg, cypress vine herb 1kg and Ramulus Persicae 6kg according to quality meter.
The described Chinese medicine composition being used for the treatment of renal calculus is granule, and its preparation method is:
(1) take Flos Cannae Indicae, cypress vine herb and Ramulus Persicae by above-mentioned quality, clean decontamination, dry, be ground into graininess;
(2) the graininess medical material of step (1) is soaked 2h, the water surface covers medical material surface 3cm;
(3) pull soaked medical material out, decoct with water three times, add the water of 10 times amount of medical material total amount for the first time, decoct 4h, filter and obtain filtrate one and filtering residue one, filtrate one is for subsequent use; Second time adds the water of 8 times amount of medical material total amount in filtering residue one, decocts 2h, and filter and obtain filtrate two and filtering residue two, filtrate two is for subsequent use; In filtering residue two, add the water of 6 times amount of medical material total amount for the third time, decoct 1h, filter and obtain filtrate three and filtering residue three, filtrate three is for subsequent use; Merging three filtrates, again filtering, through being evaporated to paste;
(4) get concentrated rear paste material, add appropriate dextrin, make granule, vacuum drying, sieve, be distributed into 1000 bags, obtain granule.
The instructions of taking of the Chinese medicine composition of the embodiment of the present invention: for oral administration, once a day, each 1 bag 15 days is a course for the treatment of.
Embodiment 3
In the embodiment of the present invention, a kind of Chinese medicine composition being used for the treatment of renal calculus, is made up of Flos Cannae Indicae 4kg, cypress vine herb 2kg and Ramulus Persicae 6kg according to quality meter.
The described Chinese medicine composition being used for the treatment of renal calculus is pill, and its preparation method is:
(1) take Flos Cannae Indicae, cypress vine herb and Ramulus Persicae by above-mentioned quality, clean decontamination, dry, be ground into graininess;
(2) the graininess medical material of step (1) is soaked 2h, the water surface covers medical material surface 3cm;
(3) pull soaked medical material out, decoct with water twice, add the water of 10 times amount of medical material total amount for the first time, decoct 4h, filter and obtain filtrate one and filtering residue one, filtrate is for subsequent use; Second time adds the water of 8 times amount of medical material total amount in filtering residue one, decocts 2h, and filter and obtain filtrate two and filtering residue two, filtrate two is for subsequent use; Merge twice filtrate, again filter, through being evaporated to paste;
(4) get concentrated rear paste material, add conventional pharmaceutical adjuvants, then technique makes pill routinely, totally 2000 balls.
The instructions of taking of the Chinese medicine composition of the embodiment of the present invention: for oral administration, once a day, each 2 balls 15 days are a course for the treatment of.
Embodiment 4
In the embodiment of the present invention, a kind of Chinese medicine composition being used for the treatment of renal calculus, is made up of Flos Cannae Indicae 7kg, cypress vine herb 2kg and Ramulus Persicae 6kg according to quality meter.
The described Chinese medicine composition being used for the treatment of renal calculus is capsule, and its preparation method is:
(1) take Flos Cannae Indicae, cypress vine herb and Ramulus Persicae by above-mentioned quality, clean decontamination, dry, be ground into graininess;
(2) the graininess medical material of step (1) is soaked 2h, the water surface covers medical material surface 3cm;
(3) pull soaked medical material out, decoct with water twice, add the water of 10 times amount of medical material total amount for the first time, decoct 4h, filter and obtain filtrate and filtering residue, filtrate is for subsequent use; Second time adds the water of 8 times amount of medical material total amount in filtering residue, decocts 2h, and filter and obtain filtrate and filtering residue, filtrate is for subsequent use; Merge twice filtrate, again filter, through being evaporated to paste;
(4) get concentrated rear paste material, add conventional pharmaceutical adjuvants, then technique makes capsule routinely, totally 3000.
The instructions of taking of the Chinese medicine composition of the embodiment of the present invention: for oral administration, once a day, each 3 15 days is a course for the treatment of.
Embodiment 5
In the embodiment of the present invention, a kind of Chinese medicine composition being used for the treatment of renal calculus, is made up of Flos Cannae Indicae 7kg, cypress vine herb 2kg and Ramulus Persicae 10kg according to quality meter.
The described Chinese medicine composition being used for the treatment of renal calculus is oral liquid, and its preparation method is:
(1) take Flos Cannae Indicae, cypress vine herb and Ramulus Persicae by above-mentioned quality, clean decontamination, dry, be ground into graininess;
(2) the graininess medical material of step (1) is soaked 2h, the water surface covers medical material surface 3cm;
(3) pull soaked medical material out, decoct with water three times, add the water of 10 times amount of medical material total amount for the first time, decoct 4h, filter and obtain filtrate one and filtering residue one, filtrate one is for subsequent use; Second time adds the water of 8 times amount of medical material total amount in filtering residue one, decocts 2h, and filter and obtain filtrate two and filtering residue two, filtrate two is for subsequent use; In filtering residue two, add the water of 6 times amount of medical material total amount for the third time, decoct 1h, filter and obtain filtrate three and filtering residue three, filtrate three is for subsequent use; Merge three filtrates, again filter, when being concentrated into 90 DEG C, relative density is the concentrated solution of 1.2g/ml;
(4) concentrated solution is placed in cold preservation 24h under 0-3 DEG C of cryogenic conditions, then toward the filter aid kieselguhr wherein adding 0.3wt%, filters and obtain filtrate, again filtrate is concentrated into every milliliter containing 2.5g crude drug amount, be placed in cold preservation 24h under 0-3 DEG C of cryogenic conditions, filter, obtain oral liquid.
The instructions of taking of the Chinese medicine composition of the embodiment of the present invention: for oral administration, once a day, each 5ml 15 days is a course for the treatment of.
According to Chinese medicine Historical Data Data About, pharmacologically active and the source of Chinese crude drug of the present invention are as follows:
Flos Cannae Indicae, cool in nature, sweet in the mouth, light, GUIXIN, spleen channel, have effect of promoting blood circulation and hemostasis.Main haematemesis; Epistaxis; Traumatic hemorrhage.Select the flower of Cannaceae herbaceos perennial Canna generalis Bailey.
Cypress vine herb: cold in nature, sweet in the mouth, has effect of heat-clearing and toxic substances removing, removing heat from blood, anti-inflammation detumescence.Cure mainly furuncle of external auditory meatus, anal fistula, venom.Select the annual weak voluble herb plant cypress vine Herb of Convolvulaceae.
Ramulus Persicae, property is put down, and bitter in the mouth, GUIXIN, stomach warp, have effect of promoting blood circulation to remove obstruction in the collateral, removing toxic substances, parasite killing.Main cardiac and abdominal pain, rheumatic arthritis, lumbago, traumatic injury, skin ulcer tinea.Select the shoot of the drying of rosaceous plant Fructus Persicae.
The present invention with the Ramulus Persicae of promoting blood circulation to remove obstruction in the collateral, removing toxic substances for principal agent, with the Flos Cannae Indicae of promoting blood circulation and hemostasis for accessory drugs, in addition the cypress vine herb of heat-clearing and toxic substances removing, removing heat from blood, anti-inflammation detumescence, all medicines share, and play promoting blood circulation and hemostasis, dredging collateral, antiinflammatory, detumescence, removing toxic substances, calculus removing effect altogether.The present invention has effect of anti-inflammation detumescence, blood circulation promoting and blood stasis dispelling, hemostasis and pain-relieving, promoting QI to circulate and dispersing the agglomeration of the pathogens, diuresis and expelling stone, is applicable to the renal calculus patient of the symptoms such as waist is ached, the whole body is weak, it is not smooth to urinate, hematuria, and evident in efficacy, has no side effect, with low cost; Compatibility science of the present invention, obviously can alleviate the pain of renal calculus patient, make ureter, the spasm of urethra alleviated, and impels urinary function normal, has significant calculus, pain palliation efficacy.
Animal acute toxicity test is carried out to foregoing invention embodiment, get Mouse and rat half and half, be divided into 5 groups, wherein first group of oral Chinese medicine composition of the present invention giving embodiment 1 preparation of 5000mg/kg, Chinese medicine composition of the present invention prepared by second group of oral embodiment 2 giving 5000mg/kg, Chinese medicine composition of the present invention prepared by the 3rd group of oral embodiment 3 giving 5000mg/kg, Chinese medicine composition of the present invention prepared by the 4th group of oral embodiment 4 giving 5000mg/kg, Chinese medicine composition of the present invention prepared by the 5th group of oral embodiment 5 giving 5000mg/kg, once a day, continue 7 days.To observation post administration 2 weeks, there is no dead mouse.The test dose adopted in animal acute toxicity test is all greater than more than 10 times of people's oral dose every day, and result shows this medicine and has no side effect.Therefore, clinical trial is carried out to the patient being diagnosed as renal calculus.
Clinical data:
1, clinical criteria.With reference to " the new Chinese medicine guideline of clinical investigations " first volume that in 1993 Ministry of Health of the People's Republic of China develops and publishes.1. medical history and symptom: the kidney having typical case to break out or ureteral colic, companion's naked eyes or microscopic hematuria; Or only have waist and belly dull pain, sour swollen discomfort, or there is calculus history; Bladder, calculus of urethra then have dysuria, and urine stream interrupts, urine retention and terminal hematuria etc.2. sign: pain or tenderness are kowtowed in acute attack Shi Shen district or ureter position; Giant hydronephrosis, renal abscess patient, can lay one's hand on and enclosed mass; Large vesical calculus often can be touched in per rectum touch; Hind urethra calculus, rectal touch can touch; Penis inspection can touch to obtain anterior urethra calculus.3. x-ray inspection: the lithangiuria of 95% develops on plain film, therefore plain film can show size, form, the number of calculus, and can stone composition according to a preliminary estimate.Plain film is negative, the person that still can not get rid of lithangiuria completely, excretory urography or ascending urography need be made, to understand the position that has that it's too late of calculus, and renal pelvis, renal calices, ureter anatomic form can be understood further, and with or without hydronephrosis and degree thereof, excess of the kidney matter thickness, renal function quality, upper urinary tract is with or without birth defect and other organic disease.4., after uroscopy: urine R-RBC often increases, especially angor outbreak or after motion, sometimes salt crystalloid can be there is, visible more leukocyte or pus cell during accompanying infection.5. ING inspection: existence and the degree thereof that can reflect renal function situation and upper urinary.6. ultrasound investigation: the degree of the existence of auxiliary diagnosis calculus and size thereof, position, hydrops.
2, case selection:
Case 200 example meeting above-mentioned clinical criteria is included in clinical trial altogether in, is divided into treatment group and matched group at random, treatment group and each 100 examples of matched group.Man 55 example, female 45 example in treatment group; Matched group man 60 example, female 40 example; Two groups of M-Fs, age size are all without significant difference.
3, medicament selection:
Treatment group takes Chinese medicine composition of the present invention, every day 1 time, and each 1 part, boiled water is decocted soup and taken; It within 15 days, is 1 course for the treatment of; Matched group takes allopurinol tablet, be grown up one time 1 ~ 3,2 ~ 3 times on the one, when half an hour ante cibum or stomachache attack, chew rear clothes.
4, curative effect determinate standard:
(1) cure: B ultrasonic display renal calculus is discharged, noresidue in body, and graft function is normal;
(2) effective: B ultrasonic display renal calculus reduces, and renal function obviously improves;
(3) effective: B ultrasonic display renal calculus reduces to some extent, renal function improves or worsens without continuation;
(4) invalid: symptom, sign are without improvement, and renal function is without improvement.
5, clinical test results:
Select in the treatment group of Chinese medicine composition of the present invention, cure 62 examples, effective 18 examples, effective 15 examples, invalid 5 examples, cure rate 62%, total effective rate 95%.
47 examples are cured, effective 17 examples, effective 18 examples, invalid 18 examples, cure rate 47%, total effective rate 82% in matched group.
Contrast therapy group and matched group, the cure rate for the treatment of group and total effective rate, apparently higher than matched group, illustrate that Chinese medicine composition of the present invention has significant effect for the treatment of renal calculus.
Model case
Case 1: Wei, man, 53 years old, people from Baoji.Patient suffered from renal calculus more than 2 years, and waist and abdominal part often understand paroxysmal pain, and after aggravating activities, pain will be shown effect sometimes, there will be lancinating pain time serious, and pain can be radiated to groin sometimes.Through ultrasound diagnosis, have 4, calculus in its kidney, wherein that maximum is 15mm × 6mm, and that minimum is 5mm × 3mm.After taking 1 course for the treatment of of Chinese medicine composition of the present invention, through ultrasound diagnosis, in its kidney, calculus becomes 3, and calculus obviously diminishes; Then after taking 1 course for the treatment of, through ultrasound diagnosis, in its kidney, calculus becomes 2, and calculus becomes less; After again taking 1 course for the treatment of, through ultrasound diagnosis, in its kidney, calculus is all discharged.Follow up a case by regular visits to half a year, have no recurrence.
Case 2: Wang, female, 58 years old, people from Xuzhou.Patient fell ill before half a year, and gnawing pains take no rest always for right side of body, and anti-inflammatory analgetic of taking medicine is invalid.Clinical diagnosis finds right ureter epimere calculus, and renal calculus, with slight hydrops.After taking 2 courses for the treatment of of Chinese medicine composition of the present invention, recovery from illness, ultrasound diagnosis, without calculus thing, follows up a case by regular visits to half a year, has no recurrence.
Case 3: Wang, female, 32 years old, Taian Shandong people.The frequent lumbago of patient, through ultrasound diagnosis, have 2 calculus in kidney, one of them calculus is 9mm × 6mm, and another is 8mm × 7mm, and after taking 1 course for the treatment of of Chinese medicine composition of the present invention, through ultrasound diagnosis, in its kidney, calculus is discharged substantially; After continuing to take 1 course for the treatment of, through ultrasound diagnosis, in its kidney, calculus is all discharged.Follow up a case by regular visits to half a year, have no recurrence.
Case 4: Wang, female, 43 years old, Lishui of Zhejiang people.Patient suffers from the ictal stomachache of interval, interrupt with urinating and urodynamic violent, while can accompany terminal hematuria, clinical diagnosis is renal calculus.After taking 2 courses for the treatment of of Chinese medicine composition of the present invention, the state of an illness alleviates to some extent; After continuing to take 2 courses for the treatment of, recovery from illness, follows up a case by regular visits to half a year, has no recurrence.
Case 5: Tang, female, 36 years old, Anhui people from Ningguo.Back lumbar part angor on the left of patient, and radiate to thigh root.Ultrasound diagnosis: the no echo area of visible 15mm × 25mm in left sinus renalis, left ureter epimere is expanded, the strong echo group of interior visible diameter 4mm, rear accompanying sound shadow.Routine urinalysis: albumen trace, erythrocyte 18-23/np, leukocyte 3-5/np, is diagnosed as calculus.After taking 1 course for the treatment of of Chinese medicine composition of the present invention, discharge the calculus of one piece of similar Semen Glycines size with urine; After continuing to take 3 courses for the treatment of, patients symptomatic, sign disappear, and X-ray, B ultrasonic display calculus shade disappears.
Case 6: Zhang, female, 29 years old, Ningbo of Zhejiang people.Patient suffers from renal calculus more than a year, and in ultrasound diagnosis kidney, calculus is 14mm × 12mm, calculus the smooth of the edge, and frequent lumbago, has some medicine when pain, and symptom can alleviate, and shows effect again after a while, and the state of an illness often repeatedly.After taking 1 course for the treatment of of Chinese medicine composition of the present invention, through ultrasound diagnosis, in its kidney, calculus is 9mm × 6mm, and lumbago obviously alleviates; Then after taking 2 courses for the treatment of, through ultrasound diagnosis, in its kidney, calculus is all discharged.
To those skilled in the art, obviously the invention is not restricted to the details of above-mentioned one exemplary embodiment, and when not deviating from spirit of the present invention or basic feature, the present invention can be realized in other specific forms.Therefore, no matter from which point, all should embodiment be regarded as exemplary, and be nonrestrictive, scope of the present invention is limited by claims instead of above-mentioned explanation, and all changes be therefore intended in the implication of the equivalency by dropping on claim and scope are included in the present invention.
In addition, be to be understood that, although this description is described according to embodiment, but not each embodiment only comprises an independently technical scheme, this narrating mode of description is only for clarity sake, those skilled in the art should by description integrally, and the technical scheme in each embodiment also through appropriately combined, can form other embodiments that it will be appreciated by those skilled in the art that.

Claims (5)

1. be used for the treatment of a Chinese medicine composition for renal calculus, it is characterized in that, be made up of Flos Cannae Indicae, cypress vine herb and Ramulus Persicae.
2. the Chinese medicine composition being used for the treatment of renal calculus according to claim 1, is characterized in that, is made up of Flos Cannae Indicae 4-7 part, cypress vine herb 1-2 part and Ramulus Persicae 6-10 part according to the raw material of mass fraction.
3. the Chinese medicine composition being used for the treatment of renal calculus is as claimed in claim 1 or 2 applied on the medicine of preparation treatment renal calculus.
4. the application being used for the treatment of the Chinese medicine composition of renal calculus according to claim 3, is characterized in that, described Chinese medicine composition is oral formulations.
5. the application being used for the treatment of the Chinese medicine composition of renal calculus according to claim 4, is characterized in that, described oral formulations is oral liquid, granule, pill or capsule.
CN201510335759.XA 2015-06-17 2015-06-17 Traditional Chinese medicinal composition for treating kidney stone and application of composition Pending CN104857198A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103550704A (en) * 2013-11-06 2014-02-05 李宏伟 Traditional Chinese medicine composition for treating kidney stones
CN104758437A (en) * 2015-03-19 2015-07-08 孙洋平 Traditional Chinese medicine composition for treating kidney stone, preparation method and application thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103550704A (en) * 2013-11-06 2014-02-05 李宏伟 Traditional Chinese medicine composition for treating kidney stones
CN104758437A (en) * 2015-03-19 2015-07-08 孙洋平 Traditional Chinese medicine composition for treating kidney stone, preparation method and application thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
易磊,牛林敬编著: "《肾病怎么吃速查手册》", 30 September 2013, 上海科学技术文献出版社 *

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Application publication date: 20150826