CN104840302A

CN104840302A - Dressing containing punched adhesive film and its manufacturing method

Info

Publication number: CN104840302A
Application number: CN201410265857.6A
Authority: CN
Inventors: 金原逸; 梁经模; 朴昶奭; 权重其; 徐民基; 权五亨
Original assignee: WONBIOGEN CO Ltd
Current assignee: WONBIOGEN CO Ltd
Priority date: 2014-02-18
Filing date: 2014-06-13
Publication date: 2015-08-19
Also published as: KR101426740B1

Abstract

The present invention relates to a dressing material laminated with an adhesive film and to a method for manufacturing the same and, more particularly, to a dressing material laminated with an adhesive film and to a method for manufacturing the same in which the adhesive film having multiple punched through-holes or a film having multiple punched through-holes is laminated on one outer side surface of the dressing material which is used for wound dressing so that injury exacerbation can be effectively prevented, healing can be performed quickly, and secondary damage can be effectively prevented.

Description

Lamination has dressing and the manufacture method thereof of bonding film

Technical field

The present invention relates to dressing and manufacture method thereof that lamination has bonding film, relate to dressing and manufacture method thereof that a kind of lamination with following feature has bonding film in more detail, by perforation have the bonding film of multiple through hole or perforation have the frlml laminating of multiple through hole in be used for repairing wound dressing outside one side, effectively can prevent the damage of wound, also its healing speed can be accelerated, in addition, can effectively avoid two degree injured.

Background technology

The process of wound, as the basis of medical science, has very long history.According to Historical Data Data About, B.C. 5000 start, and use animal oil or Mel, Cotton Gossypii and be used for the treatment of wound.Along with the development of history, the treatment technology of wound also there occurs a lot of change and progress.

Deliver from zoologist Winter in 1962 and kept percentage of wetted soil that wound is carried out dried wound and generate the method for dry crusts (crust), after more contributing to the research paper healed a wound, prove always and highlight the effectiveness of moist wounds process.Wound healing (Wet dressing) method under the body fluid do not gone out wound carries out processed or withering wet environment, is proved to be as the current method being easy to treat wound.

Desirable dressing must can keep the wet environment between wound and dressing, has suitable absorbability and poisture-penetrability, and, prevent wound surface dry, and do not cause periphery normal skin to macerate (festering).Further, there is the functions such as ventilative, to prevent outside antibacterial infection, when changing, must can not make the damaged such as cambium because being bonded at wound surface.In addition, Wound healing state can easily be observed, and nonirritant, easy use is also Eco-power, can become desirable dressing.Even to this day, also the research and development of ongoing effort always meet the dressing of whole above-mentioned ideal conditions.

Current, the kind of the main repair in trauma dressing used is as follows.Utilize the foam dressing of polyurethane or utilize the foam dressing of the natural polymers such as poly-glucosamine, the thin film by hydrogel, hydrocolloid, natural and synthesis macromolecule manufacture, the non-woven fabrics of fibrous structure by natural and synthesis macromolecule manufacture or the dressing etc. of fabric shape to be well used, but truth still there is either large or small problem.In various repair in trauma dressing, the dressing of foam form is the most conventional, shows the maximum problem of this product by typoiogical classification.

First, for polyurethane foam dressing, be divided into: the foam dressing be made up of foam itself; Wound surface contact layer is formed the self adhesive dressing of adhesive phase; With the self adhesive dressing etc. of bonding film.At this, for the foam dressing be made up of foam itself, because of the exudate absorption ability at initial stage or infiltration rate outstanding, wherein also conventional.

For the initial stage wound that exudate produces in a large number, there is not large problem, but to reduce and wound becomes dry mid-term and later stage at exudate, form a part for the foam of foam dressing because being bonded on wound, and stay and become by-product, there is the problem removed, a part for newly-generated new tissue occurring sometimes because being bonded at the problem that foam dressing comes off.

Recently, develop and use wound surface contact layer acrylic compounds or silicone based binding agent etc. being formed at foam, and improving the dressing of the problems referred to above.This wound surface contact layer is formed with certain thickness acrylic acid or silicone adhesive, has and be effectively used in the advantages such as minor wound.Relevant to it, during with reference to prior art, refer in No. 10-1073048, Ebrean Registered Patent: the binding agent adding the cooperations such as silicone adhesive, acryloid cement, reaction suppressor is formed as 20 ~ 95 μm of thickness on the wound surface contact floor of foam dressing, improve the technology of the product of convenience.

But, prior art as above because adhesive layer being formed at surface contact layer front, although be suitable for the surgical wound etc. producing a small amount of exudate, for generation as burn or a large amount of exudate such as decubital ulcer, and the wound of the large exudate of viscosity, use and there is restriction.

Further, be also present in following problem: time in foam dressing binding agent being applied directly to cellular structure, very possible blocking is for the pore absorbing exudate, and binding agents etc. permeate between this pore, thus, a large amount of uses exceed the binding agent of needs, add manufacturing cost.

In addition, for the dressing only manufactured by foam itself, also describe: in order to foam of dismantling from wound surface, or the cambium newly grown is not brought up because dismantling foam, heat and pressure are applied to the thin film of physics perforation, and make its lamination in the wound surface contact layer of foam dressing, and the product manufactured.

But have following problem: this manufacturing process is more loaded down with trivial details, and and the thin film of non-concurrent lamination perforation and the technology of foam dressing, thus, increase manufacturing cost.

Prior art document

Patent documentation

The polyurethane foam dressing that No. 10-1073048th, (patent documentation 1) Ebrean Registered Patent (2011.10.12, bulletin) ' viscosity is outstanding and manufacture method thereof '

Summary of the invention

Technical task

The present invention researches and develops for solving existing issue described above, object of the present invention is the dressing that provides a kind of lamination and have bonding film and manufacture method thereof, it is characterized in that: there is the bonding film of multiple through hole in the suitable hole of outer coversheet of the wound surface contact layer of repair in trauma dressing, effectively can prevent the damage of wound, also its healing speed is accelerated, and, can effectively prevent two degree injured.

Technical scheme

In order to realize object as above, the present invention proposes technical solution as described below.

First, dressing of the present invention, is characterized in that: by the absorber for absorption exudate; And the protective film in lamination face is thereon formed, have the vertical bonding film forming multiple through hole at the bottom surface lamination of described absorber, the bottom surface of described bonding film is formed with peeling paper.

At this, described bonding film is the area corresponding with the bottom surface of described absorber, is only formed with the vertical thin film forming multiple through hole, or also can be included in the adhesive layer of bottom surface.

And, the invention provides the dressing manufacture method that a kind of lamination has bonding film, it is characterized in that, comprise the steps: vertically to be formed with multiple through hole and foam at the certain thickness Foamex of applied atop of the bonding film of bottom surface attachment peeling paper, thus, bonding film forms absorber;

Before the absorber of described foaming formation hardens completely, carry out drying adhere to protective film on described absorber after, thus, form protecting film layer on the absorbent body.

Advantageous effects

According to the repair in trauma dressing that the invention provides a kind of lamination and be formed with the bonding film of multiple through hole.

The invention provides a kind of repair in trauma dressing using multiple material to have the laminate adhesive film of various material and form.

Especially, the present invention also tool has the following advantages: compared with existing invention, provide a kind of repair in trauma dressing of neomorph, by new and technique efficiently, greatly improve the problem of existing product, and, in substance characteristics, also more outstanding than the dressing of the high price manufactured by existing method, and be easily fabricated to all size or form.

Accompanying drawing explanation

Fig. 1 is the basic comprising figure of dressing of the present invention;

Fig. 2 is another pie graph of dressing of the present invention;

Fig. 3 is the another pie graph of dressing of the present invention;

Fig. 4 is the ground plan of the dressing of Fig. 1;

Fig. 5 is the ground plan of the dressing of Fig. 2, Fig. 3.

Reference numeral explanation

5: peeling paper 10: absorber

20: thin film 30: adhesive layer

40: protective film 50: the 2 peeling paper

60: bonding film P: through hole

Detailed description of the invention

Below, the technical scheme of the present invention of effect described above is had to illustrate in greater detail with reference to accompanying drawing to expection.

Fig. 1 is the pie graph of the dressing of one embodiment of the invention, by the absorber (10) absorbing exudate; The protective film (40) in lamination face thereon; Form at the bonding film (60) of the bottom surface lamination of described absorber (10), described bonding film (60) be vertically formed with multiple through hole (p).Outer field protective film (40) and bonding film (60) also can comprise peeling paper (50) and peeling paper (5) respectively.

At this, described bonding film (60), be formed as the area corresponding with the bottom surface of described absorber (10), also be included in bottom surface and apply certain thickness binding agent and the adhesive layer (30) formed, further, together multiple through hole is formed by perforator perforated vertical with this adhesive layer.Further, its bottom surface is attached with peeling paper (50) with outermost layer.

Described peeling paper (5) when presenting the peeling paper of fissility, can use any one for the kind according to used binding agent.

Having described peeling paper (5) at lamination and bore a hole has on the bonding film (60) of multiple through hole (p); coating Foamex and foaming and form absorber (10), and on described absorber (10) lamination protective film (40).Described Foamex, preferably, use mixes with certain proportion by the polyurethane prepolymer of isocyanate-terminated (terminated) and foamable compositions and the Foamex carrying out high-speed stirred and manufacture.

Now; preferably; the protective film (40) in described absorber (10) and lamination face thereon; by outside punching press; be caught to be attached to bonding film (60), more specifically, the protective film (40) being coated with the 2nd peeling paper (50) be attached to above absorber (10); making the pressure roller by circle, being formed by making to be formed as certain gap (gap).

The absorber (10) formed by described Foamex has porous and absorbability, plays the effect absorbing and store exudate.Form absorber (10) to by described Foamex, and the process of lamination protective film (40) further illustrates above.First; be coated on Foamex above bonding film (60) through the tens seconds time to a few minutes; stopping is foamed and the absorber (10) formed starts solidification; before thoroughly solidifying; on absorber (10) after lamination protective film (protective film (40) at the 2nd peeling paper applied atop); after treating to solidify completely; remove the 2nd peeling paper (50), form the repair in trauma dressing that lamination has the form of protective film (40) and bonding film (60).

Fig. 2 is another embodiment of dressing of the present invention, by the absorber (10) absorbing exudate; The protective film (40) of lamination above absorber (10); Form at the bonding film being vertically formed with multiple through hole (p) of the bottom surface lamination of described absorber (10), in this embodiment, illustrated described bonding film (60) is only made up of thin film (20) in FIG, does not have adhesive layer.Outer field protective film (40) and bonding film (60) also can comprise as outermost peeling paper (50) peeling paper (5).Now, equally preferably, according to the kind of thin film used, described peeling paper (5) is can lamination peeling paper (5) and the thin film (peeling paper (5) of the material of 20 well.

And; the dressing of described Fig. 2 refers at lamination on described peeling paper (5) and on perforated thin film (20); by to being undertaken mixing by the polyurethane prepolymer of isocyanate-terminated (terminated) and foamable compositions and high-speed stirred and the Foamex that manufactures; be formed at above perforated thin layer (20) with certain thickness; form absorber (10); and by protective film (40) lamination above described absorber (10), the lamination of described protective film (40) is identical with to the explanation of Fig. 1.

Fig. 3 is the another structure chart of dressing of the present invention, by the absorber (10) absorbing exudate; The protective film (40) of lamination above absorber (10); Form at the bonding film being vertically formed with multiple through hole (p) of the bottom surface lamination of described absorber (10),

Described bonding film (60) is formed as the area corresponding with the bottom surface of described absorber (10), be formed with the certain thickness binding agent of coating and the adhesive layer (30) that formed above it, together form multiple through hole by perforator perforated vertical with this adhesive layer.Further, its bottom surface also comprises with the peeling paper (5) of outermost layer attachment.

The dressing of described Fig. 3 is also identical with Fig. 1 and 2, above perforated adhesive layer (30) on the thin film (20) being formed at described perforation, will by the polyurethane prepolymer of isocyanates (isocyanate) end-blocking and foamable compositions, carry out mixing with certain proportion and the Foamex of high-speed stirred is coated on being formed at above the perforated adhesive layer (30) above thin film (20), form absorber (10), protective film (40) is formed at above described absorber (10), the forming process of described protective film is identical with Fig. 1 and Fig. 2.

As mentioned above, Fig. 1, 2, the absorber (10) used in 3 is recited as and is formed by Foamex, but the absorbent material of the fabric that described absorber (10) also can be formed by natural and synthetic fibers or non-woven fabrics form is formed, by fabric that described absorber (10) is formed as being formed by natural and synthetic fibers or non-woven fabrics form, make to absorb exudate by the through hole (p) of the perforation of described absorber (10), and prevent existing issue and namely prevent two degree injuredly (to form the foam of dressing and be bonded at wound, cambium clings dressing and comes off).

Fig. 4 is the ground plan of the dressing of display Fig. 1, and Fig. 5 is the ground plan of the dressing of display Fig. 2 and 3, and described bottom surface is direct contact portion with wound surface.

In the present invention, described thin film (20) uses the thin film manufactured by macromolecular material, most preferably, uses polyurethane, polyethylene, polypropylene, polyvinyl chloride, the materials such as thin film and synthetic fibers such as polyethylene terephthalate.

Further, form the binding agent of described adhesive layer (30), use acrylic acid, organosilicon, PUR or the material such as hydrocolloid, hydrogel.Preferably, formed by acrylic, organic silica-based macromolecule, use the binding agent of the some forms be formed as in hydrocolloid, hydrogel.

Further, described absorber (10) is made up of the water absorbing material formed a certain in foam, hydrocolloid, hydrogel.Preferably, polyurethane foam is used to be described absorber.Or the hygroscopicity fibre that described absorber (10) is formed by natural or synthesis macromolecule is formed, or is formed as the form of wrapping fibrous cloth.Such as, the non-woven fabrics by viscose glue and polyester fiber blending is used as described absorber.

Below, the described key element of the present invention of formation is further illustrated.

The polyurethane prepolymer of synthesizing isocyanate end-blocking

Concrete synthetic method, carries out with the method for the proposition in No. 10-0985969, the Ebrean Registered Patent of the applicant, synthesizes with the match ratio that table 1 shows below.

[table 1]

Manufacture foamable compositions

Concrete fitting method, carries out with the method proposed in the Ebrean Registered Patent 10-0985969 of the applicant, and has manufactured synthetic with the match ratio that table 2 shows below.

[table 2]

Classification	Use level (g)
		Deionized water (DIW)	2,000
Carboxylic methyl cellulose	40
		F-68	20
Glycerol	100
		Total manufacture (g)	2,160

Synthesis moisture-permeability waterproof polyurethane and manufacture thin film

The synthesis of moisture-permeability waterproof polyurethane resin and the manufacture of thin film, carry out with the method proposed in the Ebrean Registered Patent 10-0985969 of the applicant, and the thickness of manufactured moisture-permeability waterproof polyurethane film is 20 μm.

The manufacture of bonding film and perforation

In the present invention, employ polyurethane material, the manufacture of thin film (20) is carried out with the method proposed in the Ebrean Registered Patent 10-0985969 of the applicant.

The thickness of the thin film (20) manufactured is 20 μm, described thin film (20) uses silicone adhesive, has carried out front coating, finally, manufactures and makes adhesive layer (30) be 80 μm.Afterwards, in order to bore a hole, the method according to proposing in the Korean Application Patent 10-2013-0156187 of the applicant is bored a hole, and finally, has manufactured the bonding film being formed with through hole (p) (60).

The manufacture of thin film and perforation

In the present invention, described thin film (20) employs polyurethane material, and the manufacture of synthesis and thin film is carried out with the method proposed in the Ebrean Registered Patent 10-0985969 of the applicant.The thickness of the thin layer (20) manufactured is 20 μm, afterwards, in order to bore a hole, bore a hole with the method proposed in No. 10-2013-0156187, the Korean Application Patent of the applicant, finally having manufactured perforation is round-shaped thin film (20).

< dressing Production Example 1>

(1) on the bonding film (60) of described perforation; by the Foamex of described manufacture; namely; isocyanate-terminated polyurethane prepolymer 50 weight portion and foamable compositions 50 weight portion; stir 10 seconds with 3000RPM and the Foamex formed; above the bonding film (60) being coated on described perforation with certain thickness; form absorber (10), and the 2nd peeling paper (50) that will be coated with protective film (40) is formed in above it by circular roller bearing.

(2) after described (1) step; the absorber (10) formed by described Foamex is after about 5 minutes; carry out cured; afterwards; removal is coated with the 2nd peeling paper (50) of protective film (40); then in 40 DEG C of baking boxs, carry out dried and the maturation of 5 minutes, finally manufacture the structure shown in Fig. 1.The substance characteristics of the dressing according to said method manufactured measures with the method shown below, below table 3 show determination test result.

1. trap (%)

Dressing is chosen for 3cm × 3cm size, and places 24 hours at normal temperatures, measure initial stage weight (A) afterwards, infiltrate in 37 DEG C of distilled water and take care of taking-up after 24 hours, wiping surperficial moisture, then determine weight (B).Mathematical expression below is finally utilized to calculate.

Trap (%)=(B-A)/A × 100

2. the infiltration rate of absorbed layer

On experiment thin slice, move down on the position of about 2cm, utilize after pipette sops up the distillation of about 0.5cc, measure distilled water by the time till the complete Surface absorption from dressing.Measure 20 places altogether, show its meansigma methods.

3. moisture permeability

Utilize constant temperature and humidity instrument (SAMHEUNG INSTRUMENT, SH-CTH150), measure according to water vapo(u)r transmission standard A STME96-94 (weightening finish method), now the temperature of constant temperature and humidity instrument is set as 37 DEG C ± 2, and relative humidity set is 80% ± 5.

4. the mensuration of wound healing effect

The body weight of birth after 6 ~ 8 weeks is used to be the mouse of 250 ~ 300g and to test.Intraperitoneal anesthesia has been carried out with pentobarbital (Nembutal) mouse.Do not do the supply of endotracheal intubation or oxygen in addition, make spontaneously to breathe room air.Wipe the hair at the positions such as waist off and with depilator, hair removed completely, with polyvidone and ethanol, operative site being carried out disinfection afterwards, and carried out aseptic operation as much as possible.

Afterwards, back is formed 100 π mm ²skin injury, then cleaning wound site with normal saline, and use dry gauze wiping, then adhere to about wider than the dressing of wound site 1cm, and covered two gauzes in the above, in order to prevent dressing from coming off, having carried out fixing simply.

After completing described dressing, dressing has been changed on the 3rd, 6,9,12,15, the break-off of the degree generate the epithelization of the skin lesion sites through certain hour and the more cambium of change dressings, utilizes optical microscope to carry out biopsy, determines wound healing effect.

< dressing Production Example 2>

(1) on the thin film (20) of described perforation; by the Foamex of described manufacture; namely; the Foamex manufactured with polyurethane prepolymer 50 weight portion of 3000RPM stirring isocyanate-terminated (terminated) and foamable compositions 50 weight portion; be coated on the thin film (20) of described perforation with certain thickness, formed by circular roller bearing together with the 2nd peeling paper (50) being coated with protective film (40).

(2) after described (1) step; after having spent about 5 minutes; carry out cured; then the 2nd peeling paper (50) being coated with protective film (40) is removed; dry in 40 DEG C of baking boxs and maturation 5 minutes, has finally manufactured structure as shown in Figure 2 again.To the substance characteristics of the dressing according to said method manufactured, measure according to illustrative method in described Production Example 1, and table 3 below shows the result of the test of mensuration.

< dressing Production Example 3>

(1) on the adhesive layer (30) of the bonding film (60) of described perforation, lamination by the non-woven fabrics (Nan Yang non-woven fabrics, thickness 2mm) of viscose glue and polyester blended, and utilizes mangle to carry out lamination.

(2) in order to the upper layer part of the product manufactured in described (1) forms protective film (40); be formed with the back side of bonding film (60); aligning is coated on the protective film (40) of the 2nd peeling paper (50), and 100 DEG C of warm-up mills are set as that pressure is 2kg/cm ², speed is 1m/min, and by rear lamination, finally manufactured the product of form as shown in Figure 3.To the substance characteristics of the dressing according to said method manufactured, measure according to illustrative method in described Production Example 1, and table 3 below shows the result of the test of mensuration.

< comparative example 1>

(1) Foamex polyurethane prepolymer 50 weight portion of isocyanate-terminated (terminated) of described manufacture and foamable compositions 50 weight portion being stirred 10 minutes and be manufactured with 3000RPM; be coated in be coated with silicon peeling paper (5) above; form absorber (10), formed by circular roller bearing together with the 2nd peeling paper (50) being coated with protective film (40) above it.

(2) after described (1) step; after about 5 minutes; carry out cured; removal is coated with the 2nd peeling paper (50) of protective film (40); dry in 40 DEG C of baking boxs and maturation 5 minutes, has manufactured the product that non-lamination has the thin film (20) of perforation and the bonding film (60) of perforation again.The substance characteristics of the dressing according to said method manufactured, measures according to illustrative method in described Production Example 1, and table 3 below shows the result of the test of mensuration.

< comparative example 2>

(1) Foamex polyurethane prepolymer 50 weight portion of isocyanate-terminated (terminated) of described manufacture and foamable compositions 50 weight portion being stirred 10 minutes and be manufactured with 3000RPM; be coated in above the peeling paper (5) being coated with silicon with certain thickness, and formed by circular roller bearing together with the 2nd peeling paper (50) being coated with protective film (40).

(2) after described (1) step; after about 5 minutes; carry out cured; removal is coated with the 2nd peeling paper (50) of protective film (40); dry in 40 DEG C of baking boxs and maturation 5 minutes, has manufactured the product that non-lamination has the thin film (20) of perforation and the bonding film (60) of perforation again.

(3) the wound surface contact layer coating of the product manufactured in described (2) by silicone adhesive is 80 μm of thickness, and afterwards in hot air drying processor, and at 110 DEG C, cured 10 minutes, has manufactured product.

To the substance characteristics of the dressing according to said method manufactured, measure according to illustrative method in described Production Example 1, and table 3 below shows the result of the test of mensuration.

< comparative example 3>

Employ the non-woven fabrics proposed in dressing Production Example 3; in order to the upper layer part at non-woven fabrics forms protecting film layer (40); mutual aligning is coated on the protective film (40) of the 2nd peeling paper (50), is 2kg/cm by the warm-up mill setting pressure of 100 DEG C ², speed is 1m/min, and makes it pass through, and then carried out lamination.

After lamination described above, remove the 2nd peeling paper (50), manufacture the product that non-lamination has the thin film (20) of perforation or the bonding rete (60) of perforation.To the substance characteristics of the dressing according to said method manufactured, measure according to illustrative method in described Production Example 1, and table 3 below shows the result of the test of mensuration.

[table 3]

*: condition=37 DEG C, 80%RH

*: existing product

◎: outstanding zero: good ◇: general ×: very poor

As shown in table 3, when observation lamination has the Production Example 2 of the Production Example 1 of the bonding film of perforation (60), a laminate film (20) and does not do the comparative example 1 of any lamination, recognize trap and infiltration rate, moisture permeability etc. not by the impact of form, its measured value is certain.

And, the situation of Production Example 3, comparative example 3 too, change the kind of absorber (10) too, the situation of product that is that have a bonding film of perforation (60) for lamination and non-lamination, trap, infiltration rate, moisture permeability etc. are not by the impact of form, and its measured value is certain.

But, as shown in the situation of comparative example 2, recognize that, with the product manufactured by prior art, trap, infiltration rate, moisture permeability etc., relatively compared with the product of other Production Example, significantly reduce.

As representative of the present invention, even if lamination perforation has the bonding film (60,20) of multiple through hole (p), also can not lose or weaken the essential important function of wound dressing, and retain its function, also improve the convenience of use, and support the existing issue etc. that can improve and mention in this description.

Especially, the situation of animal clinical experimental result Production Example 1,2, absorb a large amount of exudate of wound initial stage generation well, and, do not occur in the period that middle and late stage exudate becomes dry, because foam is bonded at wound surface, and the dregs of foam are bonded at wound surface or cause the situation of damage of the cambium newly grown.

Correspondingly thereto, the situation of comparative example 2, at a large amount of initial stage producing exudate, the speed absorbing exudate is slow, there occurs the situation that a part of exudate overflows, especially, observes because moisture permeability is low, and the phenomenon that wound surface festers occurs.

The situation of comparative example 1, the function ratio comparative example 2 of absorption and management exudate is more outstanding, but repeatedly observe, more mid-term of tailing off of trend exudate and the later stage, more can cause because foam is bonded at wound surface, and cause the dregs of foam to be bonded at wound surface, or when changing, because cambium is bonded on foam, and cause two degree of injured situations.

The situation of comparative example 3, the dressing of original non-woven fabrics form is for be bonded at wound surface tightly, and cause the structure of two degree of injured problems, but as Production Example 3, when lamination has bonding film (60) of perforation, when comparing with the comparative example 3 not carrying out lamination, can recognize: be loosely bonded at wound surface, in wound healing effect, Production Example 3 is also more outstanding than comparative example 3.

According to described embodiment, describe the present invention, but also embodiment described in not according to limits scope of the present invention, in the scope not departing from technological thought of the present invention, can carry out various distortion.

Industrial applicibility

Wound dressing of the present invention utilizes the water absorbing material etc. of non-woven fabrics and fabric or the paper etc. comprised manufactured by foam (foam), hydrocolloid, hydrogel, synthetic fibers, and be fabricated to the wound dressing of various form, and be widely used in medical treatment or non-medical.

Claims

1. lamination has a dressing for bonding film, it is characterized in that:

By the absorber absorbing exudate; The protective film in lamination face thereon; Form at the bonding film being vertically formed with multiple through hole of the bottom surface lamination of described absorber, it is characterized in that:

Described absorber is under the state of the bottom surface of described bonding film attachment peeling paper, the formation of foaming at the certain thickness Foamex of the applied atop of described bonding film.

2. lamination according to claim 1 has the dressing of bonding film, it is characterized in that:

Described bonding film is also included in the adhesive layer that bottom surface is formed, and, together form multiple through hole by perforator perforated vertical with this adhesive layer.

3. lamination according to claim 1 has the dressing of bonding film, it is characterized in that:

Described bonding film is formed by a certain in polyurethane, polyethylene, polypropylene, polyvinyl chloride, polyethylene terephthalate.

4. lamination according to claim 1 has the dressing of bonding film, it is characterized in that:

Described protective film is formed by a certain in polyurethane, polyethylene, polypropylene, polyvinyl chloride, polyethylene terephthalate.

5. lamination according to claim 2 has the dressing of bonding film, it is characterized in that:

For the binding agent forming described adhesive layer, formed by acrylic compounds or silicone based macromolecule, and be formed as a certain form in PUR, hydrocolloid, hydrogel.

6. lamination according to claim 1 and 2 has the dressing of bonding film, it is characterized in that:

Also comprise in the bottom surface of described bonding film with the peeling paper of outermost layer attachment.

7. lamination according to claim 1 has the dressing of bonding film, it is characterized in that:

Described absorber is made up of polyurethane foam.

8. lamination according to claim 1 and 2 has the dressing of bonding film, it is characterized in that:

The cross sectional shape of described through hole be comprise circular or polygonal in a certain shape.

9. lamination has a dressing manufacture method for bonding film, it is characterized in that,

Comprise the steps:

Vertically be formed with multiple through hole and foam at the certain thickness Foamex of applied atop of the bonding film of bottom surface attachment peeling paper, thus, bonding film forming absorber;

10. lamination according to claim 9 has the dressing manufacture method of bonding film, it is characterized in that:

Described Foamex, end is formed by isocyanate-terminated polyurethane prepolymer and foamable compositions mixed at high speed.

11. lamination according to claim 9 have the dressing manufacture method of bonding film, it is characterized in that:

Described bonding film is also included in the adhesive layer that bottom surface is formed, and, the multiple through hole of vertical formation under the state comprising described adhesive layer, and, also comprise in the bottom surface of described bonding film with the described peeling paper of outermost layer attachment.