CN104622643A - Medical negative-pressure adsorption dressing and application thereof - Google Patents

Medical negative-pressure adsorption dressing and application thereof Download PDF

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Publication number
CN104622643A
CN104622643A CN201510047724.6A CN201510047724A CN104622643A CN 104622643 A CN104622643 A CN 104622643A CN 201510047724 A CN201510047724 A CN 201510047724A CN 104622643 A CN104622643 A CN 104622643A
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China
Prior art keywords
negative
wound surface
pressure adsorption
medical dressing
dressing
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Pending
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CN201510047724.6A
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Chinese (zh)
Inventor
徐炜
唐献忠
张扬
吴宗明
蔡振宇
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Shanghai tongren hospital
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Shanghai tongren hospital
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Priority to CN201510047724.6A priority Critical patent/CN104622643A/en
Publication of CN104622643A publication Critical patent/CN104622643A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F13/02Adhesive bandages or dressings
    • A61F13/0203Adhesive bandages or dressings with fluid retention members
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F13/02Adhesive bandages or dressings
    • A61F13/0203Adhesive bandages or dressings with fluid retention members
    • A61F13/022Adhesive bandages or dressings with fluid retention members having more than one layer with different fluid retention characteristics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F13/02Adhesive bandages or dressings
    • A61F13/0203Adhesive bandages or dressings with fluid retention members
    • A61F13/0226Adhesive bandages or dressings with fluid retention members characterised by the support layer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00Bandages or dressings; Absorbent pads
    • A61F13/02Adhesive bandages or dressings
    • A61F13/023Adhesive bandages or dressings wound covering film layers without a fluid retention layer
    • A61F13/0243Adhesive bandages or dressings wound covering film layers without a fluid retention layer characterised by the properties of the skin contacting layer, e.g. air-vapor permeability
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M27/00Drainage appliance for wounds or the like, i.e. wound drains, implanted drains

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Otolaryngology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Materials For Medical Uses (AREA)

Abstract

The invention provides a medical negative-pressure adsorption dressing and application of the medical negative-pressure adsorption dressing in wound surface healing. The medical negative-pressure adsorption dressing is made of a sheet absorbent material, the sheet absorbent material comprises an absorbent layer of a three-dimensional interworking network structure and a wound surface contact face of a three-dimensional interworking network structure, wherein the wound surface contact face is loaded on at least one side of the absorbent layer, and a plurality of negative-pressure drainage holes penetrating through the thickness portion of the sheet absorbent material and a wound observing hole are formed in the sheet absorbent material. Due to the fact that the medical negative-pressure adsorption dressing is provided with the absorbent layer of the three-dimensional interworking network structure and the negative-pressure drainage holes, thick oozed pus or blood on the wound surface is wholly and rapidly absorbed into the dressing, a wet environment of the wound surface can be kept, cellulose or protein and other solid compositions in the ooze between the wound surface and the dressing are prevented from being left, bacteria and other microorganisms are prevented from breeding on the wound surface, the opportunities of wound surface infection are greatly decreased, the wound surface can directly heal without scabbing, and the wound surface healing time is greatly shortened.

Description

Negative-pressure adsorption medical dressing and application thereof
Technical field
The present invention relates to and a kind ofly to wound surface thickness transudate, there is good absorption, wound surface moist environment, wound surface can be kept for a long time can to skip the negative-pressure adsorption medical dressing of incrustation phase adhesion.
Background technology
Traditional wound healing generally uses gauze, powder formulation, spray, ointment, cream, sponginum etc., and major part, through absorbing the transudate of wound face, makes wound location dry, then heals.In recent years, find that the healing of wound dryness exists following problem: 1) wound surface local dehydration, forms incrustation, hinder epithelial creeping; 2) wound bioactive substance is lost, and healing rate is slow; 3) frequent more change dressings, makes wound surface local temperature decline, causes cell division growth rate to slow down; 4) the without hindrance impenetrability barrier of wound surface and the external world, the chance of infection increases; 5) wound healing time is long; 6) dressing and the adhesion of wound new granulation tissue, causes property damage occurs again during each more change dressings, makes patient pain.
1962, Britain doctor Winter confirms in zoopery, under wet environment, speed of wound healing is 2 times under dryness environment, simultaneously, wound local is moistening, can not incrustation be formed, and maintain the hypoxia of wound surface local microcirculation, be beneficial to the dissolving of slough and the proliferation and differentiation of cell, retain the active substance in transudate and promote that active substance discharges, creating the healing environment close to physiological status.The advantage of wound wet union may be summarized to be: 1) closure dressing, and infection chance declines; 2) local temperature is close to body temperature, and cell division growth rate is fast; 3) wound healing time is shortened; 4) dressing not with the adhesion of wound new granulation tissue.
The material of the advanced dressing of above-mentioned wound wet environment is provided to have: film dressing, foam dressing, hydrogel, bearing hydrocolloid dressing, the dressing of alginic acid salt, exist between these advanced dressing and wounds and interact, as absorbed transudate, allow gas exchange, for ecotopia is created in healing; Prevent external environment microorganism from invading, prevent wound infection; Self has activity, and can promote has active substance to play a role, with accelerating wound healing.
In above-mentioned advanced dressing, Japanese Patent Laid-Open No. Sho 58-87153 publication discloses the dressing of a kind of polyurethane film wound, and it has good retractility, but do not absorb the performance of transudate completely, therefore, during for oozing out the wound surface of transudate, hydrops is caused, need the step of carrying out draining, in addition, adhesion strength is too strong, when causing changing, with pain, regeneration skin can be lost.
Bearing hydrocolloid dressing contains hydrophilic colloid particle, has the absorbability of transudate, but wound face easily residual spawn when changing, and not easily observes wound face, when changing, also can produce adhesion and with pain.
PVA aerogel dressing be containing have an appointment 80% water, therefore, owing to maintaining moist environment, good cooling results, and the transparency good, be easy to wound observation, but almost there is no adhesion strength, must the auxiliary immobilization materials such as binder be had.
Japanese Patent Laid-Open 8-187280 publication discloses the dressing of a kind of alginic acid salt, such dressing has the absorbability of good hemostatic and transudate, but because transudate there will be gelation, so easily remain spawn when changing on wound surface, and be open, therefore for remaining moistening, preventing antibacterial from invading, preventing bacterial multiplication, must cover with thin-film material.
Summary of the invention
The present invention solves the aforementioned problems in the prior proposition.
The invention provides a kind of negative-pressure adsorption medical dressing and the application in wound healing thereof, because described negative-pressure adsorption medical dressing has liquid-adsorption layer and the negative pressure drainage hole of three-dimensional interworking network structure, the sepage of wound surface thickness or oozing of blood entirety promptly suck in dressing, wound surface moist environment can be kept, and to avoid between wound surface and adjuvant the residual of the solid constituent such as cellulose or protein in transudate, eliminate the cultivation of the microorganisms such as antibacterial on wound surface, greatly reduce the chance of traumatic infection, wound surface can skip the adhesion of incrustation phase, substantially reduce wound healing time.
For achieving the above object, the present invention is by the following technical solutions:
First aspect of the present invention is to provide a kind of negative-pressure adsorption medical dressing, this medical dressing is lamellar imbibition material, described lamellar imbibition material comprises the liquid-adsorption layer of three-dimensional interworking network structure and has the wound surface contact surface of three-dimensional interworking network structure at least one lateral load of this liquid-adsorption layer, described lamellar imbibition material is arranged several negative pressure drainage hole and the wound observation hole of running through its thickness.
In above-mentioned negative-pressure adsorption medical dressing, preferably, the side of described imbibition material is also provided with the medical translucent pad pasting of transparent viscose.
In above-mentioned negative-pressure adsorption medical dressing, preferably, described liquid-adsorption layer is compression high-hydroscopicity polyvinyl alcohol material layer.
In above-mentioned negative-pressure adsorption medical dressing, preferably, described three-dimensional interworking network structure has the aperture being not more than 50 μm, is more preferably the aperture being not more than 45 μm, such as the aperture of 20-40 μm.
In above-mentioned negative-pressure adsorption medical dressing, preferably, the water absorbent rate of described negative-pressure adsorption medical dressing is 10-40 times, is more preferably 10-35 doubly, and such as 15-30 doubly.
In above-mentioned negative-pressure adsorption medical dressing, preferably, the absorbent time of described negative-pressure adsorption medical dressing to 500 μ l normal saline is, within 18 seconds, be more preferably 5-15 second.
In above-mentioned negative-pressure adsorption medical dressing, preferably, the moisture permeability of described negative-pressure adsorption medical dressing is determined as 500-3000g/m by cup type method 2/ 24h, is more preferably 800-2500g/m 2/ 24h.
Second aspect of the present invention is to provide the method for a kind of medical dressing healing wound surface, and described method comprises the steps:
Step 1, provide above-mentioned negative-pressure adsorption medical dressing;
After step 2, debridement wound, cover on wound with the negative-pressure adsorption medical dressing of step 1, and the medical translucent pad pasting of the transparent viscose of tearing on described negative-pressure adsorption medical dressing, with this translucent pad pasting, described medical dressing is pasted and fixed on skin;
Step 3, at any time the wound observation hole passed through on negative-pressure adsorption medical dressing observe the healing state of wound or wound surface.
In the above-mentioned methods, use translucent pad pasting that wound surface is sealed, stop antibacterial to invade, eliminate the culture environment of the growth of microorganism such as antibacterial, effectively control bacteria breed, prevention traumatic infection.The healing state of wound or wound surface can be observed by wound observation hole at any time, eliminate the misery that sufferer opens scar, avoid repeatedly changing dressings, reduce patient's misery, Economy type medicine cost.
3rd aspect of the present invention is to provide the application of above-mentioned negative-pressure adsorption medical dressing in wound healing, described negative-pressure adsorption medical dressing is covered on the wound surface after debridement, because described negative-pressure adsorption medical dressing has liquid-adsorption layer and the negative pressure drainage hole of three-dimensional interworking network structure, the sepage of wound surface thickness or oozing of blood entirety promptly suck in dressing, and wound surface skips the adhesion of incrustation phase.
In above-mentioned application, described wound surface comprises transudate that iliacus film syndrome open decompression, acute trauma, actute infection, abscess and intestinal fistula cause or the large various wound surface of other liquid local flow, or skin-grafting, transfer musculo cutaneous flap or other wound surface caused of performing the operation.
The present invention adopts technique scheme, compared with prior art, has following technique effect:
A kind of negative-pressure adsorption medical dressing provided by the invention and the application in wound healing thereof, because described negative-pressure adsorption medical dressing has liquid-adsorption layer and the negative pressure drainage hole of three-dimensional interworking network structure, the sepage of wound surface thickness or oozing of blood entirety promptly suck in dressing, wound surface moist environment can be kept, and to avoid between wound surface and adjuvant the residual of the solid constituent such as cellulose or protein in transudate, eliminate the cultivation of the microorganisms such as antibacterial on wound surface, greatly reduce the chance of traumatic infection, wound surface can skip the adhesion of incrustation phase, substantially reduce wound healing time.
Accompanying drawing explanation
Fig. 1 is the top view of negative-pressure adsorption medical dressing of the present invention;
Fig. 2 is the sectional view of negative-pressure adsorption medical dressing of the present invention;
In figure, 1-negative-pressure adsorption medical dressing, 2-negative pressure drainage hole, 3-wound observation hole, 4-liquid-adsorption layer, 5-wound surface contact surface.
Detailed description of the invention
The invention provides a kind of negative-pressure adsorption medical dressing and application thereof.
Carry out detailed and concrete introduction below by specific embodiment to the present invention, to make better to understand the present invention, but following embodiment does not limit the scope of the invention.
Composition graphs 1 and Fig. 2, the invention provides a kind of negative-pressure adsorption medical dressing 1, this medical dressing 1 is lamellar imbibition material, described lamellar imbibition material comprises the liquid-adsorption layer 4 of three-dimensional interworking network structure and has the wound surface contact surface 5 of three-dimensional interworking network structure at least one lateral load of this liquid-adsorption layer, described lamellar imbibition material is arranged several negative pressure drainage hole 2 and the wound observation hole 3 of running through its thickness.
Wherein, the side of described imbibition material is also provided with the medical translucent pad pasting (not shown) of transparent viscose.
Wherein, described liquid-adsorption layer is compression high-hydroscopicity polyvinyl alcohol material layer.
In above-mentioned negative-pressure adsorption medical dressing, preferably, described three-dimensional interworking network structure has the aperture being not more than 50 μm, is more preferably the aperture being not more than 45 μm, such as the aperture of 20-40 μm.
In above-mentioned negative-pressure adsorption medical dressing, preferably, the water absorbent rate of described negative-pressure adsorption medical dressing is 10-40 times, is more preferably 10-35 doubly, and such as 15-30 doubly.
In above-mentioned negative-pressure adsorption medical dressing, preferably, the absorbent time of described negative-pressure adsorption medical dressing to 500 μ l normal saline is, within 18 seconds, be more preferably 5-15 second.
In above-mentioned negative-pressure adsorption medical dressing, preferably, the moisture permeability of described negative-pressure adsorption medical dressing is determined as 500-3000g/m by cup type method 2/ 24h, is more preferably 800-2500g/m 2/ 24h.
test example:
The comparative example 1-2 of negative-pressure adsorption medical dressing example 1-3 provided by the invention and commercially available dressing, according to following determination of test method water absorbent rate, rate of water absorption, moisture permeability.The value measured carries out the meansigma methods of 3 times respectively, and its testing result is as shown in table 1.
water absorbent rate:
In rustless steel container, put into the normal saline (0.9%NaCl) of about 10ml, test material is cut into the test film of 4*4cm, be sealed in container and preserve 8 hours, putting into the test film weight before container is m 1g (), the test film weight of taking out after 8 hours is m 2(g), water absorbent rate Q=(m 2-m 1)/m 1.
rate of water absorption:
At the normal saline (0.9%NaCl) of the surperficial 500 μ l that drip of test film, measure the time that liquid is completely absorbed.
moisture permeability:
Measure according to the cup type method of GB 1037-88.In glass container, put into about 10ml rectification water, test material is cut into the circular test film that diameter is 80mm, test film is covered the opening of glass container, with the thin film that paraffin does, glass container is sealed, measure weight W now 0.Then, leave standstill after 24 hours in the Constant Temperature and Humidity Chambers of 40 DEG C-75%, the weight W after Measurement accuracy lets cool 1, moisture permeability=(W 1-W 0) * 10 4/ A (g/m 2/ 24h), wherein A is the area (cm of glass container peristome 2).
Table 1 testing result
application examples:
The comparative example 1-2 of negative-pressure adsorption medical dressing example 1-3 provided by the invention and commercially available dressing is attached on 10 forearms having the patient of same degree wound surface, after 24 hours, pain condition when judging skin adherence and peel off.
skin adherence:
Determinating reference: 1, without peeling off; 2, half is peeled off; 3, peel off.
Result of determination is as shown in table 2.
Table 2 skin adherence result of determination
Example 1 Example 2 Example 3 Comparative example 1 Comparative example 2
Decision content 1 1 1 2 3
pain condition during stripping:
Determinating reference: 1, completely not bitterly; 2, not too pain perception is had; 3, pain.
Result of determination is as shown in table 3.
Pain condition result of determination when table 3 is peeled off
Example 1 Example 2 Example 3 Comparative example 1 Comparative example 2
Decision content 1 1 1 3 3
Be described in detail specific embodiments of the invention above, but it is just as example, the present invention is not restricted to specific embodiment described above.To those skilled in the art, any equivalent modifications that the present invention is carried out and substituting also all among category of the present invention.Therefore, equalization conversion done without departing from the spirit and scope of the invention and amendment, all should contain within the scope of the invention.

Claims (9)

1. a negative-pressure adsorption medical dressing, it is characterized in that, this medical dressing is lamellar imbibition material, described lamellar imbibition material comprises the liquid-adsorption layer of three-dimensional interworking network structure and has the wound surface contact surface of three-dimensional interworking network structure at least one lateral load of this liquid-adsorption layer, described lamellar imbibition material is arranged several negative pressure drainage hole and the wound observation hole of running through its thickness.
2. negative-pressure adsorption medical dressing according to claim 1, is characterized in that, the side of described imbibition material is also provided with the medical translucent pad pasting of transparent viscose.
3. negative-pressure adsorption medical dressing according to claim 1, is characterized in that, described liquid-adsorption layer is compression high-hydroscopicity polyvinyl alcohol material layer.
4. negative-pressure adsorption medical dressing according to claim 1, is characterized in that, described three-dimensional interworking network structure has the aperture being not more than 50 μm.
5. negative-pressure adsorption medical dressing according to claim 1, is characterized in that, the water absorbent rate of described negative-pressure adsorption medical dressing is 10-40 times.
6. negative-pressure adsorption medical dressing according to claim 1, is characterized in that, the absorbent time of described negative-pressure adsorption medical dressing to 500 μ l normal saline is within 18 seconds.
7. negative-pressure adsorption medical dressing according to claim 1, is characterized in that, the moisture permeability of described negative-pressure adsorption medical dressing is determined as 500-3000g/m by cup type method 2/ 24h.
8. the application of negative-pressure adsorption medical dressing in wound healing as claimed in claim 1, it is characterized in that, described negative-pressure adsorption medical dressing is covered on the wound surface after debridement, because described negative-pressure adsorption medical dressing has liquid-adsorption layer and the negative pressure drainage hole of three-dimensional interworking network structure, the sepage of wound surface thickness or oozing of blood entirety promptly suck in dressing, and wound surface skips the adhesion of incrustation phase.
9. application according to claim 8, it is characterized in that, described wound surface comprises transudate that iliacus film syndrome open decompression, acute trauma, actute infection, abscess and intestinal fistula cause or the large various wound surface of other liquid local flow, or skin-grafting, transfer musculo cutaneous flap or other wound surface caused of performing the operation.
CN201510047724.6A 2015-01-29 2015-01-29 Medical negative-pressure adsorption dressing and application thereof Pending CN104622643A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105126253A (en) * 2015-08-25 2015-12-09 兰红梅 Bone injury auxiliary rehabilitation treatment apparatus
CN107854218A (en) * 2017-12-12 2018-03-30 成都美益达医疗科技有限公司 A kind of disposable hydrocolloid antibacterial application
CN109620997A (en) * 2019-01-18 2019-04-16 万绵水 Liquefaction of fat wound healing functional dressings and preparation method thereof
CN110368537A (en) * 2019-08-01 2019-10-25 苏州爱得科技发展股份有限公司 A kind of negative pressure drainage device

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101959539A (en) * 2008-02-25 2011-01-26 帝国制药株式会社 Wound-covering hydrogel material
CN103876895A (en) * 2014-03-11 2014-06-25 朱新生 Liquid absorption wound dressing enabling wound surface to be observable
KR101426740B1 (en) * 2014-02-18 2014-08-05 주식회사 원바이오젠 Dressing containing punched adhesive film and its manufacturing method
CN104188760A (en) * 2014-08-29 2014-12-10 朱新生 Dressing for overall absorption of viscous exudates and blood
CN204542566U (en) * 2015-01-29 2015-08-12 上海市同仁医院 Negative-pressure adsorption medical dressing

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101959539A (en) * 2008-02-25 2011-01-26 帝国制药株式会社 Wound-covering hydrogel material
KR101426740B1 (en) * 2014-02-18 2014-08-05 주식회사 원바이오젠 Dressing containing punched adhesive film and its manufacturing method
CN103876895A (en) * 2014-03-11 2014-06-25 朱新生 Liquid absorption wound dressing enabling wound surface to be observable
CN104188760A (en) * 2014-08-29 2014-12-10 朱新生 Dressing for overall absorption of viscous exudates and blood
CN204542566U (en) * 2015-01-29 2015-08-12 上海市同仁医院 Negative-pressure adsorption medical dressing

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105126253A (en) * 2015-08-25 2015-12-09 兰红梅 Bone injury auxiliary rehabilitation treatment apparatus
CN107854218A (en) * 2017-12-12 2018-03-30 成都美益达医疗科技有限公司 A kind of disposable hydrocolloid antibacterial application
CN109620997A (en) * 2019-01-18 2019-04-16 万绵水 Liquefaction of fat wound healing functional dressings and preparation method thereof
CN110368537A (en) * 2019-08-01 2019-10-25 苏州爱得科技发展股份有限公司 A kind of negative pressure drainage device

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Application publication date: 20150520