CN104800783A - Traditional Chinese medicine essential oil for relieving fatigue and preparation method of traditional Chinese medicine essential oil - Google Patents
Traditional Chinese medicine essential oil for relieving fatigue and preparation method of traditional Chinese medicine essential oil Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine essential oil for relieving fatigue. The traditional Chinese medicine essential oil is prepared from the following bulk drug substances in parts by mass: 9-16 parts of rhizoma gastrodiae, 5-10 parts of eriobotrya seguinii, 10-20 parts of pogostemon cablin, 8-16 parts of fructus psoraleae, 4-9 parts of raspberry, 9-16 parts of asarum sieboldii, 8-12 parts of dried ginger, 6-10 parts of leptochloa chinensis, 8-12 parts of parasitic loranthus, 9-16 parts of gardenia jasminoides, and an appropriate amount of each of melissa essential oil, spearmint essential oil, rosemary essential oil and sweet almond oil. According to the traditional Chinese medicine essential oil for relieving fatigue and the preparation method of the traditional Chinese medicine essential oil, the Chinese medicinal herbs and the natural extracting essential oils are adopted as the raw materials, so that toxic and stimulating substances are not contained, side effects on human bodies after long-term use are not caused, people are not addicted, and high safety and efficacy are achieved; besides, the contained essential oils do not generate other dangerous chemical substances after being mixed, therefore a fresh and cool fragrance is achieved, qi and blood flow freely and fatigue nerves of human bodies are fully activated through circulation of channels and collaterals.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of essential oil of traditional Chinese medicine and preparation method of fatigue alleviating.
Background technology
Along with the quickening of people's rhythm of life and the abundant of entertainment life; the sleep quality of people declines; time of having a rest is considerably reduced; many youngsters are often stayed up late work or amusement; tired, the phenomenon such as to feel sleepy easily is there is when causing them to work by day; so not only affect work efficiency, sometimes even can crisis life, the accident that China causes because of fatigue driving every year accounts for more than 40% of total vehicle accident.Moment keeps the state of visual cognitive ability, can avoid many errors that may occur in living and accident.There are many beverages with effect of refreshing oneself in the market, as happy tiger, red cattle etc., generally the compositions such as caffeine can be added in these beverages, can excited human central nervous, fatigue alleviating, but take for a long time or in a large number and can damage human body, easily produce dependence, therefore the how refreshment when fatigue, becomes a major issue.
Publication number CN 101990973 A(application number 201010564460.9) Chinese invention patent document disclose a kind of refreshing tea, it is made up of the water of following weight portion and Chinese crude drug: water 4000, Chinese crude drug 205; Wherein said Chinese crude drug comprises the raw material of following weight portion: Semen Lablab Album 10, RADIX PUERARIAE 30, Rhizoma Cyperi (processed) 10, Herba Solani Nigri 30, and Fructus Schisandrae Chinensis 10 carries Radix Ophiopogonis 5, Fructus Ligustri Lucidi 15 processed, Herba Menthae 15, Herba Agrimoniae 30, Radix Panacis Quinquefolii or Radix Pseudostellariae or Radix Ginseng 30, and white sugar 20.Publication number CN 101732458 B(application number 201010104195.6) Chinese invention patent document disclose a kind of refreshment resisting fatigue compound essential Oil and containing the wet paper towel of this quintessence oil, this compound essential Oil is prepared from by the raw material of following weight: menthol 20-50 part, fragrant cananga caul-fat 0.5-2 part, Oleum lavandula angustifolia 15-25 part, Herba Rosmarini Officinalis leaf oil 3-10 part, oleum Citri sinensis 20-30 part, cineole 15-25 part, petit grain lemon oil 20-40 part, Oleum menthae 0.1-0.2 part, Oleum Caryophylli 20-50 part, Oleum Menthae Rotundifoliae 30-55 part.Publication number CN 102793772 B(application number 201210325526.8) Chinese invention patent document disclose a kind of plants essential oil with functions of refreshing brain and restoring consciousness, be made up of the raw material of following parts by weight: Flos Rosae Rugosae volatile oil 4-8 part, Herba Agastaches Rugosae volatile oil 5-10 part, volatile oil of Radix Aucklandiae 6-12 part, Herba Menthae Haplocalycis volatile oil 3-9 part, Folium Perillae volatile oil 2-10 part.
At present, traditional mode of refreshing oneself comprises drinks pick-me-up as strong tea, coffee and functional drinks etc., and this type of mode takes effect slowly, and is not all can obtain this kind of beverage under all occasions.Therefore, develop a safe and effective, easy to carry, without the preparation of refreshing oneself of place and time restriction, have important practical significance.
Summary of the invention
For the defect of prior art, the object of this invention is to provide easy to use, be easy to carry, the essential oil of traditional Chinese medicine of a kind of fatigue alleviating of instant effect and preparation method.
Technical scheme of the present invention is:
An essential oil of traditional Chinese medicine for fatigue alleviating, is prepared from primarily of following bulk drugs, is mass parts: Rhizoma Gastrodiae 9-16; Folium Rhododendri Anthopogonoidis 5-10; Herba Pogostemonis 10-20; Fructus Psoraleae 8-16; Fructus Rubi 4-9; Herba Asari 9-16; Rhizoma Zingiberis 8-12; Semen Euphorbiae 6-10; Herba Taxilli 8-12; Fructus Gardeniae 9-16; Herba Melissae officinalis essential oil, Mentha viridis L quintessence oil, rosemary ethereal oil and Semen pruni armeniacae oil are in right amount each.
In preferred scheme, Rhizoma Gastrodiae 9-16; Folium Rhododendri Anthopogonoidis 5-10; Herba Pogostemonis 10-20; Fructus Psoraleae 8-16; Fructus Rubi 4-9; Herba Asari 9-16; Rhizoma Zingiberis 8-12; Semen Euphorbiae 6-10; Herba Taxilli 8-12; Fructus Gardeniae 9-16; Herba Melissae officinalis essential oil, Mentha viridis L quintessence oil, rosemary ethereal oil and Semen pruni armeniacae oil are in right amount each.
Be more preferably, Rhizoma Gastrodiae 9-16; Folium Rhododendri Anthopogonoidis 5-10; Herba Pogostemonis 10-20; Fructus Psoraleae 8-16; Fructus Rubi 4-9; Herba Asari 9-16; Rhizoma Zingiberis 8-12; Semen Euphorbiae 6-10; Herba Taxilli 8-12; Fructus Gardeniae 9-16; Herba Melissae officinalis essential oil, Mentha viridis L quintessence oil, rosemary ethereal oil and Semen pruni armeniacae oil are in right amount each.
The preparation method of the essential oil of traditional Chinese medicine of described a kind of fatigue alleviating is:
(1) get Semen Euphorbiae to clean, frustrate and shell, put into frying pan, intense fire heats, and fries to savory effusion, and spray clear water, takes out, dry;
(2) Fructus Psoraleae is cleaned, mix thoroughly with saline, put into pot and steam thoroughly, take out, dry;
(3) Herba Pogostemonis and Fructus Gardeniae are picked clean impurity, with step (1) (2) made crude drug, pulverized 40 mesh sieves together, and then dropped into supercritical CO
2in the extraction kettle of abstraction instrument, at pressure 22MPa, temperature 60 C, CO
2flow is 0.6m
3under the condition of/h, extraction 3-5h(is preferred, extraction 4h), extraction obtains volatile oil A;
(4) Rhizoma Gastrodiae, Folium Rhododendri Anthopogonoidis, Fructus Rubi, Herba Asari, Rhizoma Zingiberis and Herba Taxilli are cleaned, dry, pulverized 40-80 mesh sieve (preferred, to pulverize 60 mesh sieves), soaked, then vapor distillation is carried out, collect distillate, add ether (volume ratio of distillate and ether is 2:1) and extract, get upper oil phase, then add anhydrous sodium sulfate drying, obtain volatile oil B;
(5) made to step (3) (4) volatile oil A and volatile oil B mix homogeneously are obtained volatile oil 1, add Herba Melissae officinalis essential oil, Mentha viridis L quintessence oil, rosemary ethereal oil while stirring successively again, mix homogeneously, finally again mixed liquor is joined in Semen pruni armeniacae oil, stir 20 minutes, leave standstill 30 minutes, filter, obtain essential oil of traditional Chinese medicine.
The preparation method of the essential oil of traditional Chinese medicine of described a kind of fatigue alleviating, the concentration of step (2) saline is that 15%-30%(is preferred, and the concentration of saline is 20%-25%; Be more preferably, the concentration of saline is 22.5%).
The preparation method of the essential oil of traditional Chinese medicine of described a kind of fatigue alleviating, step (4) amount of water by immersion crude drug quality 9-13 doubly (preferred, amount of water by 10-12 times of immersions crude drug quality; Be more preferably, amount of water by 11 times of immersion crude drug quality).
The preparation method of the essential oil of traditional Chinese medicine of described a kind of fatigue alleviating, step (4) is soaked and (preferably, is soaked 3-5 hour in 2-6 hour; Be more preferably, soak 4 hours).
The preparation method of the essential oil of traditional Chinese medicine of described a kind of fatigue alleviating, step (4) vapor distillation extracts 6-10 hour, and (preferred, vapor distillation extracts 7-9 hour; Be more preferably, vapor distillation extracts 8 hours).
The preparation method of the essential oil of traditional Chinese medicine of described a kind of fatigue alleviating, the mass ratio of step (5) made traditional medicine volatile oil and Herba Melissae officinalis essential oil, Mentha viridis L quintessence oil, rosemary ethereal oil and Semen pruni armeniacae oil is (0.6-0.9): (0.4-0.6): (1.2-1.6): (0.7-1.3): (3-4).
The preparation method of the essential oil of traditional Chinese medicine of described a kind of fatigue alleviating, the mass ratio of step (5) made traditional medicine volatile oil and Herba Melissae officinalis essential oil, Mentha viridis L quintessence oil, rosemary ethereal oil and Semen pruni armeniacae oil is (0.7-0.8): (0.45-0.55): (1.3-1.5): (0.9-1.1): (3.2-3.8) (preferred, the mass ratio of made traditional medicine volatile oil and Herba Melissae officinalis essential oil, Mentha viridis L quintessence oil, rosemary ethereal oil and Semen pruni armeniacae oil is 0.75:0.5:1.4:1.0:3.5).
Provided by the invention have concurrently refresh oneself and the compound essential Oil of sterilizing effect easy to use, be easy to carry.In addition, excellent results of the present invention also shows:
1, the present invention adopts Chinese medicinal plant and natural extraction quintessence oil to be raw material, and not containing malicious pungent, life-time service can not have side effects to human body, not additive, safe and effective;
2, can not produce other dangerous chemicals after quintessence oil mixing contained by the present invention, fragrance is clearly insulted ice-cold, is circulated by meridians, unimpeded QI and blood, and full activation human-body fatigue is neural.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
embodiment 1an essential oil of traditional Chinese medicine for fatigue alleviating, is prepared from (every part of 10g) primarily of following bulk drugs: 9 parts, Rhizoma Gastrodiae; Folium Rhododendri Anthopogonoidis 5 parts; Herba Pogostemonis 10 parts; Fructus Psoraleae 8 parts; Fructus Rubi 4 parts; Herba Asari 9 parts; Rhizoma Zingiberis 8 parts; Semen Euphorbiae 6 parts; Herba Taxilli 8 parts; Fructus Gardeniae 9 parts; Herba Melissae officinalis essential oil (purchased from Jishui County docile citizens under a new regime or alien rulerss' medicinal flavours oil refinery, specification 1000ml, article No. 12221); Mentha viridis L quintessence oil (purchased from Guangzhou Ming Tai trade Co., Ltd, specification 1kg, article No. BE061); Rosemary ethereal oil (purchased from Guangzhou Pin Ding Chemical Industry Science Co., Ltd, specification 1kg, article No. WB-038) and Semen pruni armeniacae oil (purchased from Guangzhou Pin Ding Chemical Industry Science Co., Ltd, specification 1kg, article No. VD-003-A) in right amount each.
The preparation method of the essential oil of traditional Chinese medicine of above-mentioned a kind of fatigue alleviating is:
(1) get Semen Euphorbiae to clean, frustrate and shell, put into frying pan, intense fire heats, and fries to savory effusion, and spray clear water, takes out, dry;
(2) Fructus Psoraleae is cleaned, mix thoroughly with the saline that concentration is 15%, put into pot and steam thoroughly, take out, dry;
(3) Herba Pogostemonis and Fructus Gardeniae are picked clean impurity, with step (1) (2) made crude drug, pulverized 40 mesh sieves together, and then dropped into supercritical CO
2in the extraction kettle of abstraction instrument, at pressure 22MPa, temperature 60 C, CO
2flow is 0.6m
3under the condition of/h, extraction 3h, extraction obtains volatile oil A;
(4) Rhizoma Gastrodiae, Folium Rhododendri Anthopogonoidis, Fructus Rubi, Herba Asari, Rhizoma Zingiberis and Herba Taxilli are cleaned, dry, pulverized 40 mesh sieves, soak 2 hours (amount of water by 9 times of immersion crude drug quality), then carry out vapor distillation and extract 6 hours, collect distillate, add ether (volume ratio of distillate and ether is 2:1) to extract, get upper oil phase, then add anhydrous sodium sulfate drying, obtain volatile oil B;
(5) made to step (3) (4) volatile oil A and volatile oil B mix homogeneously are obtained volatile oil 1, add Herba Melissae officinalis essential oil, Mentha viridis L quintessence oil, rosemary ethereal oil while stirring successively again, mix homogeneously, finally again mixed liquor is joined (volatile oil 1: Herba Melissae officinalis essential oil: Mentha viridis L quintessence oil: rosemary ethereal oil: Semen pruni armeniacae oil=0.6:0.4:1.2:0.7:3 is mass ratio) in Semen pruni armeniacae oil, stir 20 minutes, leave standstill 30 minutes, filter, obtain essential oil of traditional Chinese medicine.
embodiment 2an essential oil of traditional Chinese medicine for fatigue alleviating, is prepared from (every part of 10g) primarily of following bulk drugs: 16 parts, Rhizoma Gastrodiae; Folium Rhododendri Anthopogonoidis 10 parts; Herba Pogostemonis 20 parts; Fructus Psoraleae 16 parts; Fructus Rubi 9 parts; Herba Asari 16 parts; Rhizoma Zingiberis 12 parts; Semen Euphorbiae 10 parts; Herba Taxilli 12 parts; Fructus Gardeniae 16 parts; Herba Melissae officinalis essential oil (purchased from Jishui County docile citizens under a new regime or alien rulerss' medicinal flavours oil refinery, specification 1000ml, article No. 12221); Mentha viridis L quintessence oil (purchased from Guangzhou Ming Tai trade Co., Ltd, specification 1kg, article No. BE061); Rosemary ethereal oil (purchased from Guangzhou Pin Ding Chemical Industry Science Co., Ltd, specification 1kg, article No. WB-038) and Semen pruni armeniacae oil (purchased from Guangzhou Pin Ding Chemical Industry Science Co., Ltd, specification 1kg, article No. VD-003-A) in right amount each.
A kind of preparation method of essential oil of traditional Chinese medicine of fatigue alleviating is:
(1) get Semen Euphorbiae to clean, frustrate and shell, put into frying pan, intense fire heats, and fries to savory effusion, and spray clear water, takes out, dry;
(2) Fructus Psoraleae is cleaned, mix thoroughly with the saline that concentration is 30%, put into pot and steam thoroughly, take out, dry;
(3) Herba Pogostemonis and Fructus Gardeniae are picked clean impurity, with step (1) (2) made crude drug, pulverized 40 mesh sieves together, and then dropped into supercritical CO
2in the extraction kettle of abstraction instrument, at pressure 22MPa, temperature 60 C, CO
2flow is 0.6m
3under the condition of/h, extraction 5h, extraction obtains volatile oil A;
(4) Rhizoma Gastrodiae, Folium Rhododendri Anthopogonoidis, Fructus Rubi, Herba Asari, Rhizoma Zingiberis and Herba Taxilli are cleaned, dry, pulverized 80 mesh sieves, soak 6 hours (amount of water by 13 times of immersion crude drug quality), then carry out vapor distillation and extract 10 hours, collect distillate, add ether (volume ratio of distillate and ether is 2:1) to extract, get upper oil phase, then add anhydrous sodium sulfate drying, obtain volatile oil B;
(5) made to step (3) (4) volatile oil A and volatile oil B mix homogeneously are obtained volatile oil 1, add Herba Melissae officinalis essential oil, Mentha viridis L quintessence oil, rosemary ethereal oil while stirring successively again, mix homogeneously, finally again mixed liquor is joined (volatile oil 1: Herba Melissae officinalis essential oil: Mentha viridis L quintessence oil: rosemary ethereal oil: Semen pruni armeniacae oil=0.9:0.6:1.6:1.3:4 is mass ratio) in Semen pruni armeniacae oil, stir 20 minutes, leave standstill 30 minutes, filter, obtain essential oil of traditional Chinese medicine.
Typical case: xxx, man, 36 years old.Under summer high-temperature, long-duration driving vehicle, attention cannot high concentration, occurs tried out tired, once tries drink strong tea to refresh oneself and smoking refreshment, but of long duration, poor effect.Essential oil of traditional Chinese medicine of the present invention after being introduced, in being the use of the essential oil of traditional Chinese medicine of a kind of fatigue alleviating of the present embodiment gained, when sleepy, brains is tired, opens to cover to smell under nose and hear a moment, then wiping temple, after wiping, sleepy, tired disappearance, mental restoration, visual cognitive ability, can traveling be absorbed in, avoid fatigue driving.
embodiment 3an essential oil of traditional Chinese medicine for fatigue alleviating, is prepared from (every part of 10g) primarily of following bulk drugs: 11 parts, Rhizoma Gastrodiae; Folium Rhododendri Anthopogonoidis 6 parts; Herba Pogostemonis 12 parts; Fructus Psoraleae 10 parts; Fructus Rubi 5 parts; Herba Asari 11 parts; Rhizoma Zingiberis 9 parts; Semen Euphorbiae 7 parts; Herba Taxilli 9 parts; Fructus Gardeniae 11 parts; Herba Melissae officinalis essential oil (purchased from Jishui County docile citizens under a new regime or alien rulerss' medicinal flavours oil refinery, specification 1000ml, article No. 12221); Mentha viridis L quintessence oil (purchased from Guangzhou Ming Tai trade Co., Ltd, specification 1kg, article No. BE061); Rosemary ethereal oil (purchased from Guangzhou Pin Ding Chemical Industry Science Co., Ltd, specification 1kg, article No. WB-038) and Semen pruni armeniacae oil (purchased from Guangzhou Pin Ding Chemical Industry Science Co., Ltd, specification 1kg, article No. VD-003-A) in right amount each.
A kind of preparation method of essential oil of traditional Chinese medicine of fatigue alleviating is:
(1) get Semen Euphorbiae to clean, frustrate and shell, put into frying pan, intense fire heats, and fries to savory effusion, and spray clear water, takes out, dry;
(2) Fructus Psoraleae is cleaned, mix thoroughly with the saline that concentration is 20%, put into pot and steam thoroughly, take out, dry;
(3) Herba Pogostemonis and Fructus Gardeniae are picked clean impurity, with step (1) (2) made crude drug, pulverized 40 mesh sieves together, and then dropped into supercritical CO
2in the extraction kettle of abstraction instrument, at pressure 22MPa, temperature 60 C, CO
2flow is 0.6m
3under the condition of/h, extraction 3h, extraction obtains volatile oil A;
(4) Rhizoma Gastrodiae, Folium Rhododendri Anthopogonoidis, Fructus Rubi, Herba Asari, Rhizoma Zingiberis and Herba Taxilli are cleaned, dry, pulverized 40 mesh sieves, soak 3 hours (amount of water by 10 times of immersion crude drug quality), then carry out vapor distillation and extract 7 hours, collect distillate, add ether (volume ratio of distillate and ether is 2:1) to extract, get upper oil phase, then add anhydrous sodium sulfate drying, obtain volatile oil B;
(5) made to step (3) (4) volatile oil A and volatile oil B mix homogeneously are obtained volatile oil 1, add Herba Melissae officinalis essential oil, Mentha viridis L quintessence oil, rosemary ethereal oil while stirring successively again, mix homogeneously, finally again mixed liquor is joined (volatile oil 1: Herba Melissae officinalis essential oil: Mentha viridis L quintessence oil: rosemary ethereal oil: Semen pruni armeniacae oil=0.7:0.45:1.3:0.9:3.2 is mass ratio) in Semen pruni armeniacae oil, stir 20 minutes, leave standstill 30 minutes, filter, obtain essential oil of traditional Chinese medicine.
Typical case: xxx, female, 16 years old.Enter a higher school and enter the high school-after, owing to will go up early self-study at night, do not have enough sleep, frequent classroom sleeping, is called the roll by teacher, and school grade glides, and mood is low, and shrink into oneself few speech.Once tried the multiple method controlling drowsiness, resisting fatigue, but effect is all not good.
The essential oil of traditional Chinese medicine of a kind of fatigue alleviating of rear use the present embodiment gained, when sleepy, brains is tired, open to cover and smell news for a moment under nose, then wiping temple, after wiping, sleepiness and the tired disappearance at once of brains, can absorbedly pay attention to the class, the study concentrated on, after attend class and again do not have sleepy mistake, school grade improves.
embodiment 4an essential oil of traditional Chinese medicine for fatigue alleviating, is prepared from (every part of 10g) primarily of following bulk drugs: 14 parts, Rhizoma Gastrodiae; Folium Rhododendri Anthopogonoidis 9 parts; Herba Pogostemonis 18 parts; Fructus Psoraleae 14 parts; Fructus Rubi 8 parts; Herba Asari 14 parts; Rhizoma Zingiberis 11 parts; Semen Euphorbiae 9 parts; Herba Taxilli 11 parts; Fructus Gardeniae 14 parts; Herba Melissae officinalis essential oil (purchased from Jishui County docile citizens under a new regime or alien rulerss' medicinal flavours oil refinery, specification 1000ml, article No. 12221); Mentha viridis L quintessence oil (purchased from Guangzhou Ming Tai trade Co., Ltd, specification 1kg, article No. BE061); Rosemary ethereal oil (purchased from Guangzhou Pin Ding Chemical Industry Science Co., Ltd, specification 1kg, article No. WB-038) and Semen pruni armeniacae oil (purchased from Guangzhou Pin Ding Chemical Industry Science Co., Ltd, specification 1kg, article No. VD-003-A) in right amount each.
A kind of preparation method of essential oil of traditional Chinese medicine of fatigue alleviating is:
(1) get Semen Euphorbiae to clean, frustrate and shell, put into frying pan, intense fire heats, and fries to savory effusion, and spray clear water, takes out, dry;
(2) Fructus Psoraleae is cleaned, mix thoroughly with the saline that concentration is 25%, put into pot and steam thoroughly, take out, dry;
(3) Herba Pogostemonis and Fructus Gardeniae are picked clean impurity, with step (1) (2) made crude drug, pulverized 40 mesh sieves together, and then dropped into supercritical CO
2in the extraction kettle of abstraction instrument, at pressure 22MPa, temperature 60 C, CO
2flow is 0.6m
3under the condition of/h, extraction 5h, extraction obtains volatile oil A;
(4) Rhizoma Gastrodiae, Folium Rhododendri Anthopogonoidis, Fructus Rubi, Herba Asari, Rhizoma Zingiberis and Herba Taxilli are cleaned, dry, pulverized 80 mesh sieves, soak 5 hours (amount of water by 12 times of immersion crude drug quality), then carry out vapor distillation and extract 9 hours, collect distillate, add ether (volume ratio of distillate and ether is 2:1) to extract, get upper oil phase, then add anhydrous sodium sulfate drying, obtain volatile oil B;
(5) made to step (3) (4) volatile oil A and volatile oil B mix homogeneously are obtained volatile oil 1, add Herba Melissae officinalis essential oil, Mentha viridis L quintessence oil, rosemary ethereal oil while stirring successively again, mix homogeneously, finally again mixed liquor is joined (volatile oil 1: Herba Melissae officinalis essential oil: Mentha viridis L quintessence oil: rosemary ethereal oil: Semen pruni armeniacae oil=0.8:0.55:1.5:1.1:3.8 is mass ratio) in Semen pruni armeniacae oil, stir 20 minutes, leave standstill 30 minutes, filter, obtain essential oil of traditional Chinese medicine.
embodiment 5an essential oil of traditional Chinese medicine for fatigue alleviating, is prepared from (every part of 10g) primarily of following bulk drugs: 12.5 parts, Rhizoma Gastrodiae; Folium Rhododendri Anthopogonoidis 7.5 parts; Herba Pogostemonis 15 parts; Fructus Psoraleae 12 parts; Fructus Rubi 6.5 parts; Herba Asari 12.5 parts; Rhizoma Zingiberis 10 parts; Semen Euphorbiae 8 parts; Herba Taxilli 10 parts; Fructus Gardeniae 12.5 parts; Herba Melissae officinalis essential oil (purchased from Jishui County docile citizens under a new regime or alien rulerss' medicinal flavours oil refinery, specification 1000ml, article No. 12221); Mentha viridis L quintessence oil (purchased from Guangzhou Ming Tai trade Co., Ltd, specification 1kg, article No. BE061); Rosemary ethereal oil (purchased from Guangzhou Pin Ding Chemical Industry Science Co., Ltd, specification 1kg, article No. WB-038) and Semen pruni armeniacae oil (purchased from Guangzhou Pin Ding Chemical Industry Science Co., Ltd, specification 1kg, article No. VD-003-A) in right amount each.
A kind of preparation method of essential oil of traditional Chinese medicine of fatigue alleviating is:
(1) get Semen Euphorbiae to clean, frustrate and shell, put into frying pan, intense fire heats, and fries to savory effusion, and spray clear water, takes out, dry;
(2) Fructus Psoraleae is cleaned, mix thoroughly with the saline that concentration is 22.5%, put into pot and steam thoroughly, take out, dry;
(3) Herba Pogostemonis and Fructus Gardeniae are picked clean impurity, with step (1) (2) made crude drug, pulverized 40 mesh sieves together, and then dropped into supercritical CO
2in the extraction kettle of abstraction instrument, at pressure 22MPa, temperature 60 C, CO
2flow is 0.6m
3under the condition of/h, extraction 4h, extraction obtains volatile oil A;
(4) Rhizoma Gastrodiae, Folium Rhododendri Anthopogonoidis, Fructus Rubi, Herba Asari, Rhizoma Zingiberis and Herba Taxilli are cleaned, dry, pulverized 60 mesh sieves, soak 4 hours (amount of water by 11 times of immersion crude drug quality), then carry out vapor distillation and extract 8 hours, collect distillate, add ether (volume ratio of distillate and ether is 2:1) to extract, get upper oil phase, then add anhydrous sodium sulfate drying, obtain volatile oil B;
(5) made to step (3) (4) volatile oil A and volatile oil B mix homogeneously are obtained volatile oil 1, add Herba Melissae officinalis essential oil, Mentha viridis L quintessence oil, rosemary ethereal oil while stirring successively again, mix homogeneously, finally again mixed liquor is joined in Semen pruni armeniacae oil (volatile oil 1: Herba Melissae officinalis essential oil: Mentha viridis L quintessence oil: rosemary ethereal oil: Semen pruni armeniacae oil=0.75:0.5:1.4:1.0:3.5 is mass ratio), stir 20 minutes, leave standstill 30 minutes, filter, obtain essential oil of traditional Chinese medicine.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Rhizoma Gastrodiae: base is former: be the rhizome of orchid Rhizoma Gastrodiae.Nature and flavor: sweet are flat.Gui Jing: return Liver Channel.Function cures mainly: suppressing the hyperactive liver to relieve the wind syndrome relieving convulsion.Dizzy for having a headache, numb limbs and tense tendons, infantile convulsion, epilepsy clonus, tetanus.
Folium Rhododendri Anthopogonoidis: base is former: be the leaf of ericad Rhododendron.Nature and flavor: pungent, bitter, slightly warm in nature.Function cures mainly: eliminate the phlegm, and cough-relieving is relievingd asthma.Main cough, asthma, abundant expectoration.
Herba Pogostemonis: base is former: be the aerial parts of labiate Herba Pogostemonis.Nature and flavor: pungent, tepor.Gui Jing: return spleen, stomach, lung meridian.Function cures mainly: eliminating turbid pathogen with aromatics, and appetizing preventing or arresting vomiting, delivers expelling summer-heat.For turbid damp obstructing in middle-JIAO, gastral cavity painful abdominal mass is vomitted, and heat-damp in summer asthenia is not uncomfortable in chestly relaxed, and cold-damp closes summer-heat, and stomachache is vomited and diarrhoea, nasosinusitis headache.
Fructus Psoraleae: base is former: be the fruit of legumes psoraleae.Nature and flavor: pungent, bitter, temperature.Gui Jing: return kidney, spleen channel.Function cures mainly: warming the kidney to activate YANG, improving inspiration by invigorating kidney-QI, antidiarrheal.For impotence and seminal emission, enuresis frequent micturition, chills and pain of the waist and kness, suffers from a deficiency of the kidney and breathes heavily, Diarrhoea; External curing vitiligo, alopecia areata.
Fructus Rubi: base is former: be the immature fruit of rosaceous plant Fructus Rubi, rubus coreanus etc.Nature and flavor: sweet, sour, temperature.Gui Jing: return kidney, urinary bladder channel.Function cures mainly: kidney tonifying, controlling nocturnal emission with astringent drugs, reducing urination.For enuresis due to deficiency of the kidney, frequent micturition, impotence and premature ejaculation, emission and spermatorrhea.
Herba Asari: base is former: be the whole herb with root of aristolochiaceae plant Herba Asari or magnificent Herba Asari.Nature and flavor: pungent, temperature.Gui Jing: GUIXIN, lung, kidney channel.Function cures mainly: expelling wind and cold, understand things pain-stopping, warming the lung to resolve fluid-retention.For anemofrigid cold, headache, toothache, nasal obstruction nasal sinusitis, rheumatic arthralgia, phlegm retention is breathed with cough.
Rhizoma Zingiberis: base is former: be the dry rhizome of zingiber.Nature and flavor: pungent, hot.Gui Jing: return spleen, stomach, kidney, the heart, lung meridian.Function cures mainly: Rhizoma Zingiberis warming spleen and stomach for dispelling cold, and recuperating depleted YANG is promoted blood circulation, dampness expectorant.For coldness and pain in the epigastrium, vomiting is had loose bowels, and cold extremities faint pulse, phlegm retention is breathed with cough.
Semen Euphorbiae: base is former: be the seed of euphorbia plant Euphorbia lathyris.Nature and flavor: pungent, warm; Poisonous.Gui Jing: return liver, kidney, large intestine channel.Function cures mainly: detumescence of relieving oedema or abdominal distension through diuresis or purgation, removing blood stasis eliminating mass.For edema, phlegm retention, stagnant distension, constipation and anuresis, blood stasis amenorrhea; External treatment stubborn dermatitis, warty vegetation.
Herba Taxilli: base is former: be the branch and leaf of Loranthaceae plant Herba Visci, Herba Taxilli or loranthus yadoriki etc.Nature and flavor: bitter, sweet, flat.Gui Jing: return liver, kidney channel.Function cures mainly: invigorating the liver and kidney, bone and muscle strengthening, wind-damp dispelling, antiabortive unit.For rheumatic arthralgia, soreness of the waist and knees, muscles and bones is unable, metrorrhagia through many, blood leaking in gestation, frequent fetal movement; Hypertension.
Fructus Gardeniae: base is former: be the fruit of Maguireothamnus speciosus Fructus Gardeniae.Nature and flavor: bitter, cold.Gui Jing: GUIXIN, lung, tri-jiao channel.Function cures mainly: fruit: pathogenic fire purging relieving restlessness, clearing away heat and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.Vexed for calentura, jaundice dark coloured urine, blood strangury and dry pain, heat in blood tells nosebleed, conjunctival congestion and swelling pain, pathogenic fire,toxin and furuncles; External treatment bruise pain.
Herba Melissae officinalis essential oil: be extract a kind of light lemon yellow liquid quintessence oil from Herba Melissae officinalis, pure and fresh fragrant and sweet, there is a taste for Fructus Citri Limoniae.The main place of production is at France, coratian.Herba Melissae officinalis essential oil has extraordinary effect of calming the nerves; Also be the most frequently usedly treat one of irritated quintessence oil, treatment skin or respiratory tract aspect anaphylaxis are all very effective, instill several Herba Melissae officinalis essential oil, can reach the object of meridians of invigorating blood circulation in the hot water of foot bath, can also reach the effect removing beriberi foot odor.Herba Melissae officinalis essential oil abnormal smells from the patient makes people calm and gives pleasure to please to rouse oneself, the body and mind disease caused for melancholia and anxiety etc. and vegetative dystonie.Can effectively anthelmintic, reduce by mosquito bite, can load in bottle, with distilled water diluting, be sprayed in the environment of needs and carry out pre-mosquito proof.
Mentha viridis L quintessence oil: faint yellow to slight green, fragrance band is sweet, and have fresh Herba Menthae fragrance, gentleness is not pungent.Can be used as the anesthetis of local, can treat spasm, have convergence, can get rid of the intestines and stomach intestinal inflatable, decongest, help digest, diuresis, eliminate the phlegm, make people excited and accelerate to fully recover after being ill, having can stem-winding ability, can help alleviate tired and relax dejected.
Rosemary ethereal oil: rosemary ethereal oil is a kind of colourless to faint yellow volatile liquid.Primary efficacy: 1, skin curative effect: rosemary ethereal oil has very strong contraction, tightens lax skin, also can alleviate the situation of hyperemia, swelling; The dandruff can be improved, stimulating hair growth.2, psychological effect: activating brain cell, makes sanity, memory reinforcing; Improve nervous emotion, have pent-up feeling and drowsiness; People can be allowed alive, and strengthening soul, tool improves and excitation.3, physiology curative effect: Herba Rosmarini Officinalis is the stimulant of a kind of cardiac tonic and heart, make hypotension recover normal, the effect of regulating anemia is also fine; Also helpful to lungs, flu, asthma, chronic bronchitis and influenza can be improved; Alleviate hepatitis and liver cirrhosis, and cholelithiasis, jaundice, bile duct obstruction; Strengthen digestive function, improve colitis, dyspepsia, flatulence and stomachache.4, therapeutic efficiency: 1. rosemary ethereal oil has the effect shown to brain and central nervous system, can also remove distracting thoughts and inspire intelligence.Good stimulation is also had to brain, can memory reinforcing.2. it contributes to treatment headache, migraine, neuralgia, mental fatigue and neurasthenia, effect of the antisepsis and sterilization of rosemary ethereal oil is particularly useful for intestinal infection, dysentery symptom, alleviate dyspepsia, flatulence, coordinate the symptom that liver does not accommodate jaundice, alleviate because of arthritis, rheumatism and the wind-induced pain of pain.3. it also contributes to treating arteriosclerosis, cardiopalmus, poor circulation and varicosis.4. effect of rosemary ethereal oil diuresis is conducive to reducing the menstrual phase moisture volume of holding, is also beneficial to and reduces fat and lose weight.5. for respiratory system, it is effective in cure to the cough of asthma, bronchitis, mucositis sinusitis and a sound.6. because it has astriction, positive effect is had to lax skin.Its stimulation is conducive to the growth adjusting scalp functional disorder and promote hair.
Semen pruni armeniacae oil: in aromatotherapy massage, this vegetable oil is one of the most frequently used base oil.Because it has good ductility, be easy to be absorbed by the skin, contribute to making skin soft and smooth property, and there is no greasy feeling.Faint yellow, taste is very soft, has lubricity but very salubrious.1, easily absorb, containing enriching vitamin, there is the magical effect of nourishing with moisturizing, releive and antianaphylactic effect.It is the splendid vegetable oil of a kind of skin care and moisturizing effect, for dry skin or cause the uncomfortable problem of skin extremely helpful because of climate change, can Promote cell's growth, be applicable to dry, responsive, inflammation and lacklustre skin, it is a kind of natural wetting agent.Rich in mineral substances, protein and various vitamin, be the splendid vegetable oil of a kind of skin care and moisturizing effect, be applicable to various skin quality.It effectively can alleviate skin and to itch phenomenon, eliminates red and swollen, dry and inflammation.2, the sagging gland of the brain of hormonal system, thymus and adrenal gland can be stimulated, promote cell turnover; 3, Semen pruni armeniacae oil can make skin recover smooth soft and fine, if life-time service can eliminate striae gravidarum effectively; 4, because Semen pruni armeniacae oil is very gentle, therefore connecting baby can use, and in addition for the myalgia that hyperkinesia causes, if can strengthen cell band oxygen function with Semen pruni armeniacae oil massage, allaying tiredness and carbonic acid are accumulated, and have analgesia and abirritant effect; 4, quite soft, the lubrication of almond oil, least greasy base oil, have all can be complementary with any plant characteristic, also there is the ultraviolet effect of isolation.
test example 1the clinical practice of the essential oil of traditional Chinese medicine (embodiment 5) of a kind of fatigue alleviating of gained of the present invention:
In March ,-2014 in June, 2013, screening 247 routine drivers as object of study, wherein women 68 example, male 179 example, age 20-47 year, 33.6 ± 3.8 years old mean age, driving age 2-15.
Patient is divided into two groups at random, experimental group 155 example and matched group 92 routine, two groups in sex, age, driving age, driving vehicle etc. without significant difference (P > 0.05), there is comparability.Whenever tired, sleepy, tired, experimental group uses products obtained therefrom of the present invention, directly smells suction, or wipes in temple, Fengchi acupoint and Yintang acupoint, and matched group experimenter drinks the routines such as strong tea, coffee, red cattle and to refresh oneself beverage.Observe statistics two groups of experimenter's results of use.
Experimental result: after using products obtained therefrom of the present invention when experimental group Drowsy drivers, fatigue, brains is regained consciousness at once, in high spirits, tiredness disappears, and effective percentage is 100%, drinks beverage of refreshing oneself when matched group Drowsy drivers, fatigue, only there is the people of 63%, brains recovers clear-headed, and fatigue is eased, and other people then cannot keep clear-headed continuation to drive.Illustrate that products obtained therefrom of the present invention has good fatigue alleviating, refreshment effect.
Chinese crude drug used in the present invention has the Rhizoma Gastrodiae of endogenous wind stopping relieving convulsion, the Herba Pogostemonis of eliminating phlegm and relieving asthma, the Fructus Psoraleae of warming the kidney to activate YANG, the Fructus Rubi of kidney tonifying, the Herba Asari of expelling wind and cold, the Rhizoma Zingiberis of warming spleen and stomach for dispelling cold, relieve oedema or abdominal distension through diuresis or purgation detumescence Semen Euphorbiae, the Herba Taxilli of bone and muscle strengthening, the Fructus Gardeniae of pathogenic fire purging relieving restlessness, make people calm and the happy Herba Melissae officinalis essential oil rouse oneself of joy, stem-winding Mentha viridis L quintessence oil, activating brain cell, make sanity, memory reinforcing, improve nervous emotion, have pent-up feeling and drowsiness rosemary ethereal oil, easily be absorbed by the skin, the Semen pruni armeniacae oil of lubrication, different materials is reasonably combined, not only use safety is relieved, also has good relieving brain fatigue, inspire enthusiasm, the effect of emotion of releiving.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.
Claims (10)
1. an essential oil of traditional Chinese medicine for fatigue alleviating, is characterized in that, is prepared from primarily of following bulk drugs, is mass parts: Rhizoma Gastrodiae 9-16; Folium Rhododendri Anthopogonoidis 5-10; Herba Pogostemonis 10-20; Fructus Psoraleae 8-16; Fructus Rubi 4-9; Herba Asari 9-16; Rhizoma Zingiberis 8-12; Semen Euphorbiae 6-10; Herba Taxilli 8-12; Fructus Gardeniae 9-16; Herba Melissae officinalis essential oil, Mentha viridis L quintessence oil, rosemary ethereal oil and Semen pruni armeniacae oil are in right amount each.
2. the essential oil of traditional Chinese medicine of a kind of fatigue alleviating as claimed in claim 1, is characterized in that, Rhizoma Gastrodiae 11-14; Folium Rhododendri Anthopogonoidis 6-9; Herba Pogostemonis 12-18; Fructus Psoraleae 10-14; Fructus Rubi 5-8; Herba Asari 11-14; Rhizoma Zingiberis 9-11; Semen Euphorbiae 7-9; Herba Taxilli 9-11; Fructus Gardeniae 11-14; Herba Melissae officinalis essential oil, Mentha viridis L quintessence oil, rosemary ethereal oil and Semen pruni armeniacae oil are in right amount each.
3. the essential oil of traditional Chinese medicine of a kind of fatigue alleviating as claimed in claim 1, is characterized in that, Rhizoma Gastrodiae 12.5; Folium Rhododendri Anthopogonoidis 7.5; Herba Pogostemonis 15; Fructus Psoraleae 12; Fructus Rubi 6.5; Herba Asari 12.5; Rhizoma Zingiberis 10; Semen Euphorbiae 8; Herba Taxilli 10; Fructus Gardeniae 12.5; Herba Melissae officinalis essential oil, Mentha viridis L quintessence oil, rosemary ethereal oil and Semen pruni armeniacae oil are in right amount each.
4. the preparation method of the essential oil of traditional Chinese medicine of a kind of fatigue alleviating as described in as arbitrary in claim 1-3, it is characterized in that, step is:
(1) get Semen Euphorbiae to clean, frustrate and shell, put into frying pan, intense fire heats, and fries to savory effusion, and spray clear water little Xu, takes out, dry;
(2) Fructus Psoraleae is cleaned, mix thoroughly with saline, put into pot and steam thoroughly, take out, dry;
(3) Herba Pogostemonis and Fructus Gardeniae are picked clean impurity, with step (1) (2) made crude drug, pulverized 40 mesh sieves together, and then dropped into supercritical CO
2in the extraction kettle of abstraction instrument, at pressure 22MPa, temperature 60 C, CO
2flow is 0.6m
3under the condition of/h, extraction 3-5h(is preferred, extraction 4h), extraction obtains volatile oil A;
(4) Rhizoma Gastrodiae, Folium Rhododendri Anthopogonoidis, Fructus Rubi, Herba Asari, Rhizoma Zingiberis and Herba Taxilli are cleaned, dry, pulverized 40-80 mesh sieve (preferred, to pulverize 60 mesh sieves), soaked, then vapor distillation is carried out, collect distillate, add ether (volume ratio of distillate and ether is 2:1) and extract, get upper oil phase, then add anhydrous sodium sulfate drying, obtain volatile oil B;
(5) made to step (3) (4) volatile oil A and volatile oil B mix homogeneously are obtained volatile oil 1, add Herba Melissae officinalis essential oil, Mentha viridis L quintessence oil, rosemary ethereal oil while stirring successively again, mix homogeneously, finally again mixed liquor is joined in Semen pruni armeniacae oil, stir 20 minutes, leave standstill 30 minutes, filter, obtain essential oil of traditional Chinese medicine.
5. the preparation method of the essential oil of traditional Chinese medicine of a kind of fatigue alleviating as claimed in claim 4, is characterized in that, the concentration of step (2) saline is that 15%-30%(is preferred, and the concentration of saline is 20%-25%; Be more preferably, the concentration of saline is 22.5%).
6. the preparation method of the essential oil of traditional Chinese medicine of a kind of fatigue alleviating as claimed in claim 4, is characterized in that, step (4) amount of water by immersion crude drug quality 9-13 doubly (preferred, amount of water by 10-12 times of immersions crude drug quality; Be more preferably, amount of water by 11 times of immersion crude drug quality).
7. the preparation method of the essential oil of traditional Chinese medicine of a kind of fatigue alleviating as claimed in claim 4, is characterized in that, step (4) is soaked and (preferably, soaked 3-5 hour in 2-6 hour; Be more preferably, soak 4 hours).
8. the preparation method of the essential oil of traditional Chinese medicine of a kind of fatigue alleviating as claimed in claim 4, is characterized in that, step (4) vapor distillation extracts 6-10 hour, and (preferred, vapor distillation extracts 7-9 hour; Be more preferably, vapor distillation extracts 8 hours).
9. the preparation method of the essential oil of traditional Chinese medicine of a kind of fatigue alleviating as claimed in claim 4, it is characterized in that, the made volatile oil 1 of step (5) is (0.6-0.9) with the mass ratio of Herba Melissae officinalis essential oil, Mentha viridis L quintessence oil, rosemary ethereal oil and Semen pruni armeniacae oil: (0.4-0.6): (1.2-1.6): (0.7-1.3): (3-4).
10. the preparation method of the essential oil of traditional Chinese medicine of a kind of fatigue alleviating as claimed in claim 4, it is characterized in that, the made volatile oil 1 of step (5) is (0.7-0.8) with the mass ratio of Herba Melissae officinalis essential oil, Mentha viridis L quintessence oil, rosemary ethereal oil and Semen pruni armeniacae oil: (0.45-0.55): (1.3-1.5): (0.9-1.1): (3.2-3.8) (preferred, made volatile oil 1 is 0.75:0.5:1.4:1.0:3.5 with the mass ratio of Herba Melissae officinalis essential oil, Mentha viridis L quintessence oil, rosemary ethereal oil and Semen pruni armeniacae oil).
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