CN104800774A - Compound for improving sleeping quality and application thereof - Google Patents
Compound for improving sleeping quality and application thereof Download PDFInfo
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- CN104800774A CN104800774A CN201510250650.6A CN201510250650A CN104800774A CN 104800774 A CN104800774 A CN 104800774A CN 201510250650 A CN201510250650 A CN 201510250650A CN 104800774 A CN104800774 A CN 104800774A
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- quintessence oil
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- radix curcumae
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Abstract
The invention provides a compound for improving sleeping quality. The compound is prepared from the following raw materials in proportion by weight: 2 to 8 parts of lavender essential oil, 2 to 8 parts of tulip essential oil, 1 to 5 parts of rosemary essential oil and 1 to 5 parts of jasmine essential oil. The invention also provides the application of the compound. The sleeping quality is reduced by discomfort of a human body, but the sleeping quality can be improved by the compound, the using effect of the compound is more obvious than that of single essential oil in the compound, and the application range of the compound is wider; the compound has better effect on symptoms, such as insomnia, dreaminess, wakeful state and easiness in waking at midnight, caused by discomfort of the human body; the essential oils are compatible and are matched with one another to be used, a synergistic interaction effect is achieved, an essential oil formula is subjected to inhalation administration at a nasal splint, and the compound is more simple and convenient in use and is portable.
Description
Technical field
The present invention relates to a kind of compositions improving sleep quality.
Background technology
Sleep is a kind of spontaneous and reversible quiescent condition that higher vertebrate periodically occurs, the brief interruption that the reactivity that showing as body stimulates to external world reduces and realizes.The time in all one's life nearly 1/3 of people is spent in sleep.When people are in sleep state, the brain of people and health can be made to obtain having a rest, rest and reorganize and recovering, and appropriate sleep contributes to the daily working and learning of people.Science improves sleep quality, is the guarantee of the normal work and study life of people.
Current commercially available quintessence oil kind is many, is generally folk prescription quintessence oil, and most consumer is unfamiliar with allotment quintessence oil, and applicable surface is narrower.
Summary of the invention
The object of the present invention is to provide a kind of compositions improving sleep quality.Another object of the present invention is to the purposes that said composition is provided.
Present invention also offers a kind of compositions improving sleep quality, it is prepared from by the raw material of following weight proportioning:
Herba Lysimachiae foenum-graeci quintessence oil: 2-8 part, Radix Curcumae quintessence oil: 2-8 part, rosemary ethereal oil 1-5 part, jasmin quintessence oil 1-5 part.
Further preferably, it is prepared from by the raw material of following weight proportioning:
Herba Lysimachiae foenum-graeci quintessence oil: 5 parts, Radix Curcumae quintessence oil: 5 parts, rosemary ethereal oil 3 parts, jasmin quintessence oil 2 parts.
Wherein, described Herba Lysimachiae foenum-graeci quintessence oil, Radix Curcumae quintessence oil, rosemary ethereal oil, jasmin quintessence oil be respectively by lavandula angustifolia, Radix Curcumae, Herba Rosmarini Officinalis, jasmine is raw material, adopts the volatile oil that steam distillation, low polar organic solvent extraction method or carbon dioxide supercritical extraction method prepare.
Wherein, it is active component by described raw material, adds the preparation that adjuvant conventional in pharmacy or health product or complementary composition are prepared from.
Wherein, described preparation is aerosol, spray, fumigating agent, Nasal inhalant.
Present invention also offers the purposes of described compositions in the medicine or health product of preparation raising sleep quality.
Wherein, described medicine or health product be used for the treatment of, prevent or improve insomnia, dreaminess, keep alert while in bed, midnight easily wakes up the medicine of symptom or health product.
In present composition raw material prescription, jasmin quintessence oil is a kind of active drug for the treatment of severe psychiatric and constraining, and can console nerve, sets up a kind of self-confident, has sensation that is optimistic and euphoria, can regain one's vigor.Rosemary ethereal oil can control headache, very beneficial to respiratory system, declines very effective to the sleep quality caused that had some setbacks by headache, respiratory system.Radix Curcumae quintessence oil promoting flow of QI and blood, heart fire-clearing upset-relieving, improve in insomnia because QI and blood does not freely cause and dream and faint from fear.The emotion of Herba Lysimachiae foenum-graeci quintessence oil energy propitiator, has good effect to negative psychological state, and energy centre of equilibrium is neural, reduces hypertension, adjustment is breathed, and help enters sleep.
Stagnation resolving in Radix Curcumae, promoting flow of QI and blood, improve health, Herba Rosmarini Officinalis specially controls the sleep quality decline because headache, head discomfort cause, lavandula angustifolia can reduce blood pressure, to be still in night excited central nervous system adjust breathing and Herba Rosmarini Officinalis coordinate, effect is better, jasmin quintessence oil can loosen mood, also has certain help to respiratory problems.
The present composition can improve because of various uncomfortable and the sleep quality that causes declines, and the effect be used alone than folk prescription quintessence oil a certain in compositions is more obvious, and the scope of application is wider; To insomnia, the dreaminess of multiple uncomfortable initiation, keep alert while in bed, midnight the symptom such as Yi Xing all have better effect; Various quintessence oil compatibility uses, and has the effect of Synergistic, and essential oil is used for nose clip inhalation, use easier, be easy to carry.
Obviously, according to foregoing of the present invention, according to ordinary technical knowledge and the customary means of this area, not departing under the present invention's above-mentioned basic fundamental thought prerequisite, the amendment of other various ways, replacement or change can also be made.
The detailed description of the invention of form by the following examples, is described in further detail foregoing of the present invention again.But this should be interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to following example.All technology realized based on foregoing of the present invention all belong to scope of the present invention.
Detailed description of the invention
The various quintessence oils that the present invention uses, can obtain by buying commercially available prod, conventional essential oil extraction method also can be adopted to be prepared, as steam distillation, low polar organic solvent extraction method, supercritical carbon dioxide extraction method etc.The various quintessence oil of extraction by steam distillation is adopted in the present invention:
After lavandula angustifolia coarse crushing, cross 40 mesh sieves, lavandula angustifolia coarse powder is put into boiler, adds 8 times of water loggings in pot and cross the bed of material, distill 4 hours, from collection liquid, be separated volatilization oil reservoir, obtain Herba Lysimachiae foenum-graeci quintessence oil.
After Radix Curcumae coarse crushing, cross 40 mesh sieves, Radix Curcumae coarse powder is put into boiler, adds 12 times of water loggings in pot and cross the bed of material, distill 5 hours, from collection liquid, be separated volatilization oil reservoir, obtain Radix Curcumae quintessence oil.
After Herba Rosmarini Officinalis coarse crushing, Herba Rosmarini Officinalis coarse powder puts into boiler, adds 15 times of water loggings and cross the bed of material in pot, soaks 3 hours, distills 4 hours, is separated volatilization oil reservoir, obtains rosemary ethereal oil from collection liquid.
Be placed on sealing flower stand with jasmine, Flos Jasmini Sambac layer is continued to flow through with wet air, the gas convulsion with aromatic substance flowed out is sent in adsorption tower, the mixture " face cream " of 3 parts of axunges and 2 part of 2 Adeps Bovis seu Bubali is placed in order to adsorb aromatic substance in tower, after having adsorbed, add dehydrated alcohol, in " face cream ", volatile oil is proposed, decompression recycling ethanol, obtains jasmin quintessence oil.
The preparation of embodiment 1 present composition
Herba Lysimachiae foenum-graeci quintessence oil: 5g, Radix Curcumae quintessence oil: 5g, rosemary ethereal oil: 3g, jasmin quintessence oil: 2g.After each quintessence oil mixing, obtain the present composition.
With average 0.3cm
3activated carbon granule absorption quintessence oil to full, each nose clip is joined 2.
Wear nasal cavity medicine applicator before sleeping every day, wear to sleep end, average 6-8 hour.
After absorbent charcoal carrier absorption quintessence oil, be positioned over nasal cavity front portion, carry out auxiliary treatment with suction-type method.
Beneficial effect of the present invention is proved below by way of concrete Ergonomy test.
The efficacy test of test example 1 present composition
Accept standard for medical treatment: sleep quality immunocompromised patients is totally 108 examples.
The symptom that patient occurs comprises insomnia, dreaminess, keeps alert while in bed, midnight easily wakes up.
Test example 2 medicament composing prescription screening test of the present invention
(1) contrast groups 1:
Radix Curcumae quintessence oil: 5 parts, rosemary ethereal oil: 3 parts, jasmin quintessence oil: 2 parts
Nasal cavity medicine applicator is prepared, every consumption per day 1 (using dosage is identical with of the present invention group) according to embodiment 1 method.
Nasal cavity medicine applicator prepared by contrast groups 1 and embodiment 1 is treated 30 people respectively, and it the results are shown in following table:
Table 1 pharmaceutical composition and contrast groups are on the impact of patient's insomnia
(2) contrast groups 2:
Herba Lysimachiae foenum-graeci quintessence oil: 5 parts, rosemary ethereal oil: 3 parts, jasmin quintessence oil: 2 parts
Nasal cavity medicine applicator is prepared, every consumption per day 1 (using dosage is identical with of the present invention group) according to embodiment 1 method.
Nasal cavity medicine applicator prepared by contrast groups 2 and embodiment 1 is treated 30 people respectively, and it the results are shown in following table:
Table 2 pharmaceutical composition and contrast groups are on the impact of patient's insomnia
(3) contrast groups 3:
Herba Lysimachiae foenum-graeci quintessence oil: 5 parts, Radix Curcumae quintessence oil: 5 parts, jasmin quintessence oil: 2 parts
Nasal cavity medicine applicator is prepared, every consumption per day 1 (using dosage is identical with of the present invention group) according to embodiment 1 method.
Nasal cavity medicine applicator prepared by contrast groups 3 and embodiment 1 is treated 30 people respectively, and it the results are shown in following table:
Table 3 pharmaceutical composition and contrast groups are on the impact of patient's insomnia
(4) contrast groups 4:
Herba Lysimachiae foenum-graeci quintessence oil: 5 parts, Radix Curcumae quintessence oil: 5 parts, rosemary ethereal oil: 3 parts
Nasal cavity medicine applicator is prepared, every consumption per day 1 (using dosage is identical with of the present invention group) according to embodiment 1 method.
Nasal cavity medicine applicator prepared by contrast groups 4 and embodiment 1 is treated 30 people respectively, and it the results are shown in following table:
Table 4 pharmaceutical composition and contrast groups are on the impact of patient's insomnia
Test example 3 medicine of the present invention and folk prescription quintessence oil comparative efficacy test
Embodiment 1: mixed essential oil 5g
Contrast groups 1: Herba Lysimachiae foenum-graeci quintessence oil 5g
Contrast groups 2: rosemary ethereal oil 5g
Contrast groups 3: Radix Curcumae quintessence oil 5g
Contrast groups 4: jasmin quintessence oil 5g
Nasal cavity medicine applicator is prepared, the every consumption per day of each group 1 according to embodiment 1 method.(using dosage is identical with of the present invention group).
Nasal cavity medicine applicator prepared by contrast groups 1,2,3,4 and embodiment 1 is treated 20 people respectively, and it the results are shown in following table:
Table 5 pharmaceutical composition and contrast groups are on the impact of all kinds of insomnia of patient
Experimental result shows, four kinds of specific compatibilities of prescription of the present invention, compared with being used alone, the effect be used alone with folk prescription quintessence oil is more remarkable, has synergistic function.
Claims (7)
1. improve a compositions for sleep quality, it is characterized in that: it is prepared from by the raw material of following weight proportioning:
Herba Lysimachiae foenum-graeci quintessence oil: 2-8 part, Radix Curcumae quintessence oil: 2-8 part, rosemary ethereal oil 1-5 part, jasmin quintessence oil 1-5 part.
2. compositions according to claim 1, is characterized in that: it is prepared from by the raw material of following weight proportioning:
Herba Lysimachiae foenum-graeci quintessence oil: 5 parts, Radix Curcumae quintessence oil: 5 parts, rosemary ethereal oil 3 parts, jasmin quintessence oil 2 parts.
3. compositions according to claim 1 and 2, it is characterized in that: described Herba Lysimachiae foenum-graeci quintessence oil, Radix Curcumae quintessence oil, rosemary ethereal oil, jasmin quintessence oil be respectively by lavandula angustifolia, Radix Curcumae, Herba Rosmarini Officinalis, jasmine is raw material, adopts the volatile oil that steam distillation, low polar organic solvent extraction method or carbon dioxide supercritical extraction method prepare.
4. the compositions according to claim 1-3 any one, is characterized in that: it is active component by described raw material, adds the preparation that adjuvant conventional in pharmacy or health product or complementary composition are prepared from.
5. compositions according to claim 4, is characterized in that: described preparation is aerosol, spray, fumigating agent, Nasal inhalant.
6. the purposes of compositions described in Claims 1 to 5 any one in the medicine or health product of preparation raising sleep quality.
7. purposes according to claim 6, is characterized in that: described medicine or health product be used for the treatment of, prevent or improve insomnia, dreaminess, keep alert while in bed, midnight easily wakes up the medicine of symptom or health product.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201510250650.6A CN104800774B (en) | 2015-05-15 | 2015-05-15 | A kind of composition for improving sleep quality and application thereof |
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| CN201510250650.6A CN104800774B (en) | 2015-05-15 | 2015-05-15 | A kind of composition for improving sleep quality and application thereof |
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| CN104800774A true CN104800774A (en) | 2015-07-29 |
| CN104800774B CN104800774B (en) | 2018-05-18 |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105239198A (en) * | 2015-09-30 | 2016-01-13 | 丹阳市超超服饰有限公司 | Production technology of oil-resistant non-woven fabric capable of improving sleep quality |
| CN113842417A (en) * | 2020-11-10 | 2021-12-28 | 深圳蔚多科技有限公司 | Herbal formula for relieving and helping sleep and preparation method |
| CN115887559A (en) * | 2022-04-29 | 2023-04-04 | 福建省海乐威生物工程有限公司 | Jasmine composition for helping sleep and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1743633A1 (en) * | 2004-04-06 | 2007-01-17 | Taiyokagaku Co., Ltd. | Sleep-improving composition |
| CN102670012A (en) * | 2011-03-10 | 2012-09-19 | 陈登 | Insomnia-curing herb-filled pillow |
-
2015
- 2015-05-15 CN CN201510250650.6A patent/CN104800774B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1743633A1 (en) * | 2004-04-06 | 2007-01-17 | Taiyokagaku Co., Ltd. | Sleep-improving composition |
| CN102670012A (en) * | 2011-03-10 | 2012-09-19 | 陈登 | Insomnia-curing herb-filled pillow |
Non-Patent Citations (4)
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| 《读者参考从书》编辑部: "《活出诗意》", 31 October 2014 * |
| 李雪琴: "《吃出你的天才记忆力》", 30 April 2013 * |
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| 黄惠琦等: "《0到100岁的经络芳疗》", 31 July 2009 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105239198A (en) * | 2015-09-30 | 2016-01-13 | 丹阳市超超服饰有限公司 | Production technology of oil-resistant non-woven fabric capable of improving sleep quality |
| CN113842417A (en) * | 2020-11-10 | 2021-12-28 | 深圳蔚多科技有限公司 | Herbal formula for relieving and helping sleep and preparation method |
| CN115887559A (en) * | 2022-04-29 | 2023-04-04 | 福建省海乐威生物工程有限公司 | Jasmine composition for helping sleep and preparation method thereof |
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| CN104800774B (en) | 2018-05-18 |
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